Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.Rete Testis: The network of channels formed at the termination of the straight SEMINIFEROUS TUBULES in the mediastinum testis. Rete testis channels drain into the efferent ductules that pass into the caput EPIDIDYMIS.Spermatogenesis: The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.Sertoli Cells: Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.Cryptorchidism: A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.Leydig Cells: Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.Spermatids: Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA.Spermatozoa: Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.Spermatogonia: Euploid male germ cells of an early stage of SPERMATOGENESIS, derived from prespermatogonia. With the onset of puberty, spermatogonia at the basement membrane of the seminiferous tubule proliferate by mitotic then meiotic divisions and give rise to the haploid SPERMATOCYTES.Epididymis: The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.Seminiferous Epithelium: The epithelium lining the seminiferous tubules composed of primary male germ cells (SPERMATOGONIA) and supporting SERTOLI CELLS. As SPERMATOGENESIS proceeds, the developing germ cells migrate toward the lumen. The adluminal compartment, the inner two thirds of the tubules, contains SPERMATOCYTES and the more advanced germ cells.Testicular Diseases: Pathological processes of the TESTIS.Testosterone: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.Spermatocytes: Male germ cells derived from SPERMATOGONIA. The euploid primary spermatocytes undergo MEIOSIS and give rise to the haploid secondary spermatocytes which in turn give rise to SPERMATIDS.Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.Sperm Count: A count of SPERM in the ejaculum, expressed as number per milliliter.Organ Size: The measurement of an organ in volume, mass, or heaviness.Spermatic Cord Torsion: The twisting of the SPERMATIC CORD due to an anatomical abnormality that left the TESTIS mobile and dangling in the SCROTUM. The initial effect of testicular torsion is obstruction of venous return. Depending on the duration and degree of cord rotation, testicular symptoms range from EDEMA to interrupted arterial flow and testicular pain. If blood flow to testis is absent for 4 to 6 h, SPERMATOGENESIS may be permanently lost.Infertility, Male: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.Germ Cells: The reproductive cells in multicellular organisms at various stages during GAMETOGENESIS.Orchitis: Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.Genitalia, Male: The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).Sexual Maturation: Achievement of full sexual capacity in animals and in humans.Scrotum: A cutaneous pouch of skin containing the testicles and spermatic cords.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Blood-Testis Barrier: A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Sex Differentiation: The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain.Organ Specificity: Characteristic restricted to a particular organ of the body, such as a cell type, metabolic response or expression of a particular protein or antigen.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Orchiectomy: The surgical removal of one or both testicles.Ovary: The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.Sex-Determining Region Y Protein: A transcription factor that plays an essential role in the development of the TESTES. It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors.Fertility: The capacity to conceive or to induce conception. It may refer to either the male or female.Seminal Vesicles: A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)DNA, Complementary: Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.Sex Determination Processes: The mechanisms by which the SEX of an individual's GONADS are fixed.Follicle Stimulating Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.Gonads: The gamete-producing glands, OVARY or TESTIS.Sertoli Cell Tumor: Gonadal neoplasm composed entirely of SERTOLI CELLS or may have a component of GRANULOSA CELLS. Some of the Sertoli cell tumors produce ESTROGEN or ANDROGENS, but seldom in sufficient quantity to cause clinical symptoms such as FEMINIZATION or masculinization (VIRILISM).In Situ Hybridization: A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.Orchiopexy: A surgical procedure in which an undescended testicle is sutured inside the SCROTUM in male infants or children to correct CRYPTORCHIDISM. Orchiopexy is also performed to treat TESTICULAR TORSION in adults and adolescents.Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Blotting, Northern: Detection of RNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Sperm Motility: Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.Luteinizing Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.Seminoma: A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)Testicular Hormones: Hormones produced in the testis.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Sperm Maturation: The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.Varicocele: A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.Spermatic Cord: Either of a pair of tubular structures formed by DUCTUS DEFERENS; ARTERIES; VEINS; LYMPHATIC VESSELS; and nerves. The spermatic cord extends from the deep inguinal ring through the INGUINAL CANAL to the TESTIS in the SCROTUM.Meiosis: A type of CELL NUCLEUS division, occurring during maturation of the GERM CELLS. Two successive cell nucleus divisions following a single chromosome duplication (S PHASE) result in daughter cells with half the number of CHROMOSOMES as the parent cells.Inhibins: Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectivelySOX9 Transcription Factor: A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; and male sex determination. Loss of function of the SOX9 transcription factor due to genetic mutations is a cause of CAMPOMELIC DYSPLASIA.Genes, sry: The primary testis-determining gene in mammalians, located on the Y CHROMOSOME. It codes for a high mobility group box transcription factor (TRANSCRIPTION FACTORS) which initiates the development of the TESTES from the embryonic GONADS.Diethylhexyl Phthalate: An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)
Blood supply and lymphatic drainage. Blood supply and lymphatic drainage of the testes and scrotum are distinct:. *The paired ... The blood-testis barrier. Large molecules cannot pass from the blood into the lumen of a seminiferous tubule due to the ... The original Latin word testis, "witness", was used in the firmly established legal principle "Testis unus, testis nullus" (one ... Hydrocele testis, swelling around testes caused by accumulation of clear liquid within a membranous sac, the testis usually ...
Bladder cancer Blood in urine. Prostate cancer Urgency, hesitancy and frequency while passing urine, bony pain. Testis cancer ... Blood cancer Bleeding manifestations including bleeding gums, bleeding from nose, blood in vomitus, blood in sputum, blood ... Blood investigations including haemoglobin, total leukocyte count, platelet count, peripheral smear, red cell indices. Bone ... Blood investigations including Lactate dehydrogenase (LDH), Serum Uric Acid, Renal Functions. Imaging tests like Computerised ...
Blood. 112 (4): 1413-23. doi:10.1182/blood-2007-07-104257. PMC 2967309 . PMID 18524993. Herrero AB, San Miguel J, Gutierrez NC ... Nikolova T, Christmann M, Kaina B (2009). "FEN1 is overexpressed in testis, lung and brain tumors". Anticancer Res. 29 (7): ...
1992). "Effect of activin A on globin gene expression in purified human erythroid progenitors". Blood. 79 (3): 773-81. PMID ... 1992). "Immunolocalization of inhibin alpha-subunit in the human testis. A light- and electron-microscopy study". Cell Tissue ...
The drug is highly lipophilic and able to cross the blood brain barrier at higher doses. COL-3 accumulates in higher ... concentration in heart tissue and testis. In clinical trials plasma protein binding has been shown to be high (~94,5%). Most ...
In addition the blood testis barrier provides architectural support and is composed of tight junction components such as ... These tight junctions form the blood testis barrier (BTB) and have been suggested to play a role in isolating differentiated ... Jul 2010). "Molecular dynamics of the blood-testis barrier components during murine spermatogenesis". Mol Reprod Dev. 77 (7): ... The testis GSC niche is built around a population of non-mitotic hub cells (a.k.a. niche cells), to which two populations of ...
... because the cerebral blood flow is inadequate to support synaptic function although there is still sufficient blood flow to ... This test-the apnoea test-is dangerous - and may prove lethal. Two doctors, of specified status and experience, are required to ... That being so, proper caution must be exercised in accepting a diagnosis of its permanent loss before all cerebral blood flow ... There is published evidence strongly suggestive of the persistence of brainstem blood pressure control in organ donors. A small ...
The blood-testis barrier separates the immune system and the developing spermatozoa. The tight junction between the Sertoli ... or immunological interactions across the blood-testis barrier. The concept has been used by fertility clinics to explain the ... cells form the blood-testis barrier but it is usually breached by physiological leakage. Not all sperms are protected by the ...
Blood. 117 (13): 3669-79. doi:10.1182/blood-2010-04-282350. PMID 21263153. Denny P, Swift S, Brand N, Dabhade N, Barton P, ... a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147-51. doi:10.1016/S0014-5793(00) ... Ashworth A (Jun 1992). "A conserved family of genes related to the testis determining gene, SRY". Nucleic Acids Research. 20 ( ... a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147-51. doi:10.1016/S0014-5793(00) ...
Blood. 99 (1): 275-81. doi:10.1182/blood.V99.1.275. PMID 11756182. Cai Y, Gao Y, Sheng Q, Miao S, Cui X, Wang L, Zong S, Koide ... SS (2002). "Characterization and potential function of a novel testis-specific nucleoporin BS-63". Mol. Reprod. Dev. 61 (1): ... Blood. 85 (6): 1435-41. PMID 7888665. "Entrez Gene: MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, ...
In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter. Spermatic cord Artery to ... The artery to the ductus deferens (deferential artery) is an artery in males that provides blood to the ductus deferens. The ... It accompanies the ductus deferens into the testis, where it anastomoses with the testicular artery. ... Scrotum and Testes: Layers of the Spermatic Cord". ...
Blood in urine.[31]. Prostate cancer. Urgency, hesitancy and frequency while passing urine, bony pain.[32]. Testis cancer. ... Blood cancer. Bleeding manifestations including bleeding gums, bleeding from nose, blood in vomitus, blood in sputum, blood ... Blood cancerEdit. Blood investigations including hemoglobin, total leukocyte count, platelet count, peripheral smear, red cell ... Swelling of testis, back pain, dyspnoea.[33]. Bone cancer. Pain and swelling of bones.[34]. Lymphoma. Fever, weight loss more ...
Spermatozoa are protected from the male's immune system by the blood-testis barrier. However, spermatozoa are deposited into ... Blood samples were taken twice a month, and booster injections were given when antibody titers declined below 50 ng/mL in women ... A novel family of protease inhibitors expressed in the epididymis and testis". Gene. 270: 93-102. doi:10.1016/s0378-1119(01) ... fish exposed to treated sewage effluents were found to have concentrations of the synthetic hormone levonorgestrel in blood ...
Mital, Payal; Hinton, Barry T.; Dufour, Jannette M. (2011-05-01). "The blood-testis and blood-epididymis barriers are more than ... its incompleteness at a region called the rete testis and (2) the presence of immunogenic molecules outside the blood-testis ... The blood-testis barrier is likely to contribute to the survival of sperm. However, it is believed in the field of testicular ... They create the Sertoli cell barrier, which complements the blood-testis barrier. The protection is ensured by tight junctions ...
However due to the presence of blood-testis barrier, chemotherapeutic agents are unable to reach the testis, hence in boys with ... The appendix testis is attached to the upper pole of the testis and found in the groove between the testis and the epididymis. ... In the testis, the seminiferous tubules converge to form the rete testes, which is located in the mediastinum testis. The rete ... Failure in the course of testes descent will result in undescended testes (Cryptorchidism). Undescended testis is found in 4% ...
It is able to cross the blood-testis barrier and blood-brain barrier. The oral LD50 of 3-chloro-1,2-propanediol is 152 mg/kg ...
This cools the blood heading to the testis, while reheating the returning blood. "Countercurrent" heat exchangers occur ... In species that have external testes (such as humans), the artery to the testis is surrounded by a mesh of veins called the ... Arteries to the skin carrying warm blood are intertwined with veins from the skin carrying cold blood, causing the warm ... The blood ascending the carotid arteries on its way to the brain, flows via a network of vessels where heat is discharged to ...
It has moderate expression in testis, larynx, nerve, blood, and adipose tissue sites. According to the Human Protein Atlas, ...
... its incompleteness at a region called the rete testis and (2) the presence of immunogenic molecules outside the blood-testis ... Neutrophils are white blood cells which are present in the blood but not normally in tissues. They move out from the blood into ... The blood-testis barrier is likely to contribute to the survival of sperm. However, it is believed in the field of testicular ... They originate from blood monocytes which move into the testis then mature into macrophages. In the rat, testicular macrophages ...
... 5 is not expressed in the kidney but in the testis. UT-B is widely expressed and has been studied in ... erythrocytes, kidney, intestine, and at the blood-brain barrier. The SLC14A1 gene codes for the UT-B protein. UT-B is expressed ...
... and HIV-infected white blood cells, thereby avoiding an immune response from the host organism. The blood-testis barrier, ... The blood-testis barrier is also important in preventing toxic substances from disrupting spermatogenesis. Fertilization relies ... prevents communication between the forming spermatozoa in the testis and the blood vessels (and immune cells circulating within ... Spermatozoa are produced in the seminiferous tubules of the testes in a process called spermatogenesis. Round cells called ...
... Messenger RNA has been detected in human pancreas, placenta, liver, testis, and heart. The expression in the heart ... Several ApO isoforms are expressed predominantly in blood vessels suggesting that ApO plays a role in vascular cell biology. ...
These sites include the brain, the anterior chamber of the eye, the testes and the fetus. These areas are protected by several ... Anatomical barriers can separate the lymphocytes from the antigen, an example is the central nervous system (the blood-brain- ... This can occur in the testes, for instance. ... and blood-tissue-barrier with tight junctions between ...
... testis, prostate, thyroid, breast, blood flow (Warsaw). Shana Penn; Jill Massino (24 November 2009). Gender Politics and ...
Additionally V1R are located in brain, testis, superior cervical ganglion, liver, blood vessels, and renal medulla. V1R is ... Vasopressin acts on medullary vasculature through V1R to reduce blood flow to inner medulla without affecting blood flow to ...
... the highest levels of acrylamide post-exposure are found in the blood, non-exposed skin, kidneys, liver, testes, and spleen. ... It has been shown in one study to cause an increase in blood acrylamide levels three-fold greater than any dietary factor. ... In animal models, exposure to acrylamide causes tumors in the adrenal glands, thyroid, lungs, and testes. Acrylamide is easily ...
blood vessel remodeling. •skeletal muscle tissue development. •respiratory gaseous exchange. •blood circulation. •cell ...
However, C15orf52 protein is relatively over-expressed in the colon, peripheral blood mononuclear cells, testis, and rectum. ...
Treatment of malposition testis (undescended testicle, cryptorchidism) with hormonal stimulation (costs for program #154403) ✔ ... complete blood count,\/li,\n\t\t,li,general urine analysis,\/li,\n\t\t,li,biochemical analysis of blood,\/li,\n\t\t,li, ... Malposition testis (undescended testicle, cryptorchidism) Total amount * Program [Description]. Treatment of malposition testis ... Treatment of malposition testis (undescended testicle, cryptorchidism) with hormonal stimulation (program ID: 154403) Head ...
Diagnostics of malposition testis (undescended testicle, cryptorchidism) (costs for program #227735) ✔ University Hospital ... complete blood count,\/li,\n\t\t,li,general urine analysis,\/li,\n\t\t,li,biochemical analysis of blood,\/li,\n\t\t,li, ... Malposition testis (undescended testicle, cryptorchidism) Total amount * Program [Description]. Diagnostics of malposition ... Diagnostics of malposition testis (undescended testicle, cryptorchidism) (program ID: 227735) Head Physician ...
Testes get their blood supply from 3 sources. They are testicular artery from abdominal aorta, artery to the vas from internal ... Testes get blood supply from testicular artery, cremasteric artery and artery to the vas deference. So ligation of testicular ... The internal inguinal ring was identified by slight traction on the testis from outside. The traction on the testis causes ... The goal of treatment of the varicocele is to obstruct the refluxing venous drainage to the testis. No accessory veins or vene ...
SPAG5 mRNA is predominantly expressed in testis in pachytene spermatocytes. This observation prompted us to evaluate the ... SPAG5 mRNA is predominantly expressed in testis in pachytene spermatocytes. This observation prompted us to evaluate the ... SPAG5 mRNA is over-expressed in peripheral blood leukocytes of patients with Downs syndrome and cryptorchidism. ... SPAG5 mRNA is over-expressed in peripheral blood leukocytes of patients with Downs syndrome and cryptorchidism. ...
The subsequent equalization of venous blood return and arterial blood pressure compromises the arterial flow resulting in ... A midscrotal incision was performed to gain access to both testes torsion was induced by twisting the testes 7200 in ... Testis was maintained in the torted position (T) for 1, 2, 3 and 4 hr in subgroups AT1+PM, AT2+PM, AT3+PM, and AT4+ PM (Group A ... Testis maintained in the torted position (T) for 1, 2, 3 and 4 hr in Group A (subgroups: AT1+PM, AT2+PM, AT3+PM, and AT4+PM). ...
Sperm are constantly being made in the testis. Sperm, once made in the testis, travel through a series of tubes called the ... The testicular artery supplies blood to the testicle and the testicular vein drains blood from the testicle. There maybe a ... A varicocele is dilated veins in the scrotum, often described as a "bag of worms". These veins carry blood from the testicle ... This is thought to be because the varicocele increases the temperature of the testis. ...
... an area of connective tissue at the back of the testis. The veins of the plexus ascend along the spermatic cord ... The plexus begins in the scrotum with veins arising from the mediastinum testis, ... mechanism to cool down the blood. The arteries supplying the testes run through the plexus where the blood is cooled from ... The plexus begins in the scrotum with veins arising from the mediastinum testis, an area of connective tissue at the back of ...
... which in turn regulates testosterone production in the testes. Low testosterone can also be caused by failure of the testes to ... Testosterone is a very important hormone which affects many functions of the body including metabolism, reproduction, red blood ... Testosterone is produced primarily in testes in men. Small amount of testosterone is also produced in the adrenal glands. ... In men who desire fertility, testosterone replacement therapy may affect fertility potential of the testes and a carefully ...
Blood-Testis Barrier: Medical Dictionary [home, info] *blood-testis barrier: online medical dictionary [home, info] *Blood- ... We found 7 dictionaries that include the word blood-testis barrier: General (2 matching dictionaries). *Blood-testis barrier: ... Blood-testis barrier: Legal dictionary [home, info] Computing (1 matching dictionary). *Blood-testis barrier: Encyclopedia [ ... Search for blood-testis barrier on Google or Wikipedia Search completed in 0.018 seconds.. Home Reverse Dictionary Customize ...
Blood-air barrier Blood-brain barrier Blood-ocular barrier Blood-retinal barrier Blood-thymus barrier Spermatogenesis Ganong. ... The blood-testis barrier is a physical barrier between the blood vessels and the seminiferous tubules of the animal testes. The ... The blood-testes barrier can be damaged by trauma to the testes (including torsion or impact), by surgery or as a result of ... This composition is maintained by blood-testis barrier. The barrier also protects the germ cells from blood-borne noxious ...
Regulation of the blood-testis barrier by a local axis in the testis: Role of laminin α2 in the basement membrane Authors: Ying ... mTORC1/rpS6 regulates blood-testis barrier (BTB) dynamics and spermatogenetic function in the testis in vivo Authors: Stephen Y ... Unlike most blood-tissue barriers, the blood-testis barrier has been found to be made up of specialized, extremely tight ... The blood-testis barrier is a physical barrier separating the testes from the bloodstream. The barrier can be breached, however ...
Damage to the integrity of the blood-testis barrier (BTB), which ensures spermatogenesis, was assessed by transmission electron ... Metformin alleviated the decrease in male fertility, decreased ectopic lipid deposition in the testis, and increased serum FSH ... In the testes of the oral metformin mice, the fluorescence intensity of ROS (. vs. , ) and concentration of MDA (. vs. , ) ... Metformin treatment resulted in a significant decrease of the expression level of NF-κB/p65 in the whole testis (. vs. and vs. ...
What is blood-testis barrier? Meaning of blood-testis barrier medical term. What does blood-testis barrier mean? ... Looking for online definition of blood-testis barrier in the Medical Dictionary? blood-testis barrier explanation free. ... blood-gas barrier alveolocapillary membrane.. blood-testis barrier a barrier separating the blood from the seminiferous tubules ... Blood-testis barrier and spermatogenesis: Lessons from geneticallymodified mice.. An in vivo study on adjudin and blood-testis ...
2008) An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during ... 2012) The blood-testis barrier and its implications for male contraception. Pharmacol Rev 64:16-64. ... Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat. Pearl P. Y. ... 2011) An in vitro system to study Sertoli cell blood-testis barrier dynamics. Methods Mol Biol 763:237-252. ...
... than in normal testis (0.5 pmol/mg protein). In the SCE testis neither blood-testis barrier development nor lumen formation are ... ABP is found in normal testis as early as 14 days postnatally (0.2 pmol/mg), at which time no blood-testis barrier is observed ... Androgen binding protein as a biochemical marker of formation of the blood-testis barrier.. Tindall DJ, Vitale R, Means AR. ... Indeed, ABP is not detectable in the epididymis until 18-20 days of age (1.0 pmol/mg) at which time blood-testis barrier ...
Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma. Blood, 97(5), 1508-1510. Accessed September 22, 2019. ... Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma. Seah H. Lim, Zhiqing Wang, Maurizio Chiriva-Internati ... Your Name) has forwarded a page to you from Blood Journal Message Body (Your Name) thought you would be interested in this ... Thank you for sharing this Blood Journal article.. NOTE: We request your email address only to inform the recipient that it was ...
This information is based on the routine use of this system in our laboratory to study the Sertoli cell blood-testis barrier in ... based on primary cultures of Sertoli cells isolated from rat testes has greatly facilitated the study of the blood-testis ... An in vitro system to study Sertoli cell blood-testis barrier dynamics. ... and the use of the Sertoli cell epithelium for monitoring the integrity of the Sertoli cell blood-testis barrier. ...
What is Blood-testis barrier? Meaning of Blood-testis barrier as a finance term. What does Blood-testis barrier mean in finance ... Definition of Blood-testis barrier in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Blood-testis barrier financial definition of Blood-testis barrier https://financial-dictionary.thefreedictionary.com/Blood- ... The blood-testis barrier is damaged, and the immune system becomes inoculated with testis antigens and anti-sperm antibodies ...
... the authors examined hemodynamic and histological changes in both testes after acute testicular torsion in neonatal piglets. ... Regional Blood Flow. Spermatic Cord Torsion / pathology*, physiopathology*. Swine. Testis / blood supply*, pathology*. ... The testes also were examined blindly with routine and electron microscopy. RESULTS: In group I, testicular blood flow ... Sham-operated animals showed no histological abnormality in either testis. In all torsion groups, the affected testis showed ...
Drug Transport Across the Blood-Testis and Blood-Epididymal Barriers (R61/R33 - Clinical Trial Not Allowed) PAR-18-853. NICHD ... Drug Transport Across the Blood-Testis and Blood-Epididymal Barriers (R61/R33 - Clinical Trial Not Allowed) ... These targets are not fully exposed to the systemic circulation due to the semi-permeable nature of the blood-testis barrier ( ... to elucidate the chemical features of non-native molecules that facilitate passage across the blood-testis and/or blood- ...
Nucleoside Transport at the Blood-Testis Barrier Studied with Primary-Cultured Sertoli Cells. Ryo Kato, Tomoji Maeda, Toshihiro ... Nucleoside Transport at the Blood-Testis Barrier Studied with Primary-Cultured Sertoli Cells. Ryo Kato, Tomoji Maeda, Toshihiro ... Nucleoside Transport at the Blood-Testis Barrier Studied with Primary-Cultured Sertoli Cells. Ryo Kato, Tomoji Maeda, Toshihiro ... Nucleoside Transport at the Blood-Testis Barrier Studied with Primary-Cultured Sertoli Cells ...
Zhai, J., Geng, X., Ding, T. et al. An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis ... Li N, Mruk DD, Cheng CY (2015) Actin binding proteins in blood-testis barrier function. Curr Opin Endocrinol Diabetes Obes 22: ... Wan HT, Mruk DD, Wong CK, Cheng CY (2014) Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier ... Because molecular mechanisms such as remodeling of the blood-testis barrier (BTB) play crucial roles in spermatogenesis, we ...
... claudin-11 is responsible for the formation of specific parallel TJ strands of the blood-testis barrier (BTB). Concerning the ... In mouse testis, claudin-11 is responsible for the formation of specific parallel TJ strands of the blood-testis barrier (BTB ... Claudin-11 Is Over-Expressed and Dislocated From the Blood-Testis Barrier in Sertoli Cells Associated With Testicular ...
... the blood-testis barrier (BTB) or Sertoli cell barrier created by specialized junctions between Sertoli cells near the basement ... In mammalian testes, the blood-testis barrier (BTB) or Sertoli cell barrier created by specialized junctions between Sertoli ... Blood-Testis Barrier*. Connexin 43 / physiology*. Homeostasis / physiology*. Humans. Male. Phenols / pharmacology. RNA ... Despite being one of the tightest blood-tissue barriers, the BTB has to restructure cyclically during spermatogenesis. A recent ...
Ratio of drug uptake in testes to blood in mdr1a knock-out mouse at 18.5 MBq, iv after 90 mins postinjection. ...
  • SPAG5 mRNA is over-expressed in peripheral blood leukocytes of patients with Down's syndrome and cryptorchidism. (unict.it)
  • This observation prompted us to evaluate the expression of SPAG5 gene in five DS men with cryptorchidism and five normal healthy men (controls) by quantitative real-time PCR in peripheral blood leukocytes. (unict.it)
  • In oncology, the experts treat patients with kidney cancer, prostate cancer, bladder cancer and with tumors of the posterior abdominal area, the testes and the ureter. (bookinghealth.com)
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