Blood Specimen Collection
Specimen Handling
Sensitivity and Specificity
Clinical Laboratory Techniques
Urine
Polymerase Chain Reaction
Reagent Kits, Diagnostic
Quality Control
Disease Outbreaks
Reproducibility of Results
Blood
Phlebotomy
Evaluation Studies as Topic
Blood Preservation
HIV Seroprevalence
Virology
Ehrlichia
Substance Abuse Detection
Cytomegalovirus
Gas Chromatography-Mass Spectrometry
Plasma
AIDS Serodiagnosis
Cytomegalovirus Infections
Bacteremia
Neonatal Screening
Data Collection
Ehrlichiosis
Neoplastic Cells, Circulating
Filtration
Centrifugation
False Positive Reactions
Prospective Studies
Fetal Blood
Seroepidemiologic Studies
Genotype
Case-Control Studies
Sequence Analysis, DNA
Immunosurveillance and the evaluation of national immunization programmes: a population-based approach. (1/1207)
Mass vaccination can change the epidemiological dynamics of infectious diseases. It may result in a limited persistence of natural and vaccine-induced immunity and a higher mean age of infection, which may lead to a greater risk of complications. The epidemiological situation should be monitored and immunosurveillance based on the assessment of specific antibodies against vaccine-preventable diseases in human serum is one of the tools. In order to estimate the immunity of the Dutch population reliably, a large-scale, population-based, collection of serum samples was established (8359 sera in a nation-wide sampling and 1589 sera from municipalities with low vaccine coverage). In contrast to collecting residual sera from laboratories, this approach gains extensive information by means of a questionnaire regarding the determinants of the immune status and the risk factors for the transmission of infectious diseases in general. The population-based approach gives a better guarantee that the data are representative than collecting sera from laboratories does. (+info)A method for collecting right coronary venous blood samples from conscious dogs. (2/1207)
This report describes for the first time a technique to collect right coronary venous blood samples from conscious dogs. Catheters, prepared from Micro-Renathane tubing, were surgically implanted in right ventricular superficial veins of three anesthetized dogs. Also implanted were an arterial catheter, a right coronary flow transducer, and a right coronary artery constrictor. The coronary catheter was introduced at a venous bifurcation so that its side holes were positioned above the bifurcation; both ends of the catheter were exteriorized. Heparinized saline was continuously infused through the venous catheter by a battery-powered pump. The dogs were maintained for 10-13 days after surgery, and all catheters remained patent. Multiple right coronary venous samples were collected from each dog. These samples were analyzed for venous oxygen tension (PvO2) under baseline conditions, with right coronary pressure reduced to 50 mmHg, and during the reactive hyperemia after release of the right coronary artery constriction. PvO2 was 27.7 +/- 1.0 mmHg at baseline, 23.4 +/- 1.0 mmHg during coronary artery constriction, and 34.3 +/- 1.5 mmHg during reactive hyperemia. These data and the position of the catheter at autopsy demonstrated that coronary venous blood had been sampled. (+info)Reducing bruising after venepuncture. (3/1207)
Bruising after venepuncture is undesirable. To verify an apparent increase in bruising after introducing a new venepuncture system in a small district general hospital and to improve the venepuncture service two prospective audits of the incidence and severity of bruising after venepuncture were performed in two groups of 100 consecutive inpatients undergoing venepuncture by phlebotomists. In the first audit bruising was detected in 45 patients, of whom 34(76%) had bruises > 100 mm2 in area. After modification of the technique, whereby the phlebotomists ensured that haemostasis had been attained before leaving the patient, bruising was significantly reduced, occurring in 25 patients only 9 of whom (36%) had bruises > 100mm2 in area (both p < 0.01) in the second audit. Monitoring of standards and simple modification of technique resulted in significant reduction in incidence and severity of bruising, improving the quality of the venepuncture service. (+info)Randomised controlled trial of paracetamol for heel prick pain in neonates. (4/1207)
AIM: To evaluate the effectiveness of paracetamol in decreasing the pain from heel prick. METHODS: A prospective randomised double blind placebo controlled trial was conducted of 75 term neonates undergoing heel prick. Sixty to 90 minutes before the procedure neonates received paracetamol orally in a dose of 20 mg/kg (group 1) or an equal volume of placebo (group 2). Heel prick was performed in a standardised manner. Pain assessments were made using per cent facial action (brow bulge, eye squeeze, and nasolabial fold (range 0-300%) and per cent of time spent crying (range 0-100%). RESULTS: Thirty eight neonates were enrolled in group 1 and 37 neonates in group 2. There were no significant differences in the demographic characteristics between groups. Mean gestational age was 39 (SD 1.4) vs 39.4 (SD 1.2) weeks, p = 0.86, mean birthweight 3.45 (SD 0.45) vs 3.44 (SD 0.42) kg; p = 0.31 for groups 1 and 2, respectively. Facial action pain scores did not differ between groups (143.5 (SD 54.2)% vs 131.1 (SD 59.6)%; p = 0.38). Cry scores also did not differ (29.4 (SD 19.9)% vs 26.8 (SD 20.2)%; p = 0.60). No adverse effects were observed. CONCLUSION: Paracetamol is ineffective for decreasing the pain from heel prick in term neonates. (+info)Stem cell mobilization with G-CSF alone in breast cancer patients: higher progenitor cell yield by delivering divided doses (2 x 5 microg/kg) compared to a single dose (1 x 10 microg/kg). (5/1207)
We investigated the schedule dependency of G-CSF (10 microg/kg) alone in mobilizing peripheral blood progenitor cells (PBPC) in breast cancer patients. After a median of three cycles (range, 2-6) of anthracycline-based chemotherapy, 49 patients with breast cancer (stage II/III, > or = 10+ Ln n = 36; locally advanced/inflammatory n = 8, stage IV (NED) n = 5) underwent PBPC collection after steady-state mobilization either with 1 x 10 microg/kg (n = 27) or with 2 x 5 microg/kg (n = 22) G-CSF daily for 4 consecutive days until completion of apheresis. Apheresis was started on day 5. Priming with 2 x 5 microg/kg resulted in a higher median number of CD34+ cells (5.8 vs 1.9 x 10(6)/kg, P = 0.003), MNC (6.6 vs 2.6 x 10(8)/kg, P < 0.001) and CFU-GM (6.5 vs 1.3 x 10(4)/kg, P = 0.001) in the first apheresis than with 1 x 10 microg/kg. Also the overall number of collected BFU-E was higher in the 2 x 5 microg group (9.2 vs 3.1 x 10(4)/kg; P = 0.01). After high-dose chemotherapy with cyclophosphamide/thiotepa/mitoxantrone (n = 46) hematopoietic engraftment with leukocyte count > 1.0/nl was reached in both groups after a median of 10 days (range, 8-15) and with platelets count > 50/nl after 12 (range, 9-40) and 13 days (range, 12-41), respectively. A threshold of > 2.5 x 10(6)/kg reinfused CD34+ cells ensured rapid platelet engraftment (12 vs 17 days; P = 0.12). Therefore, the target of collecting > 2.5 x 10(6) CD34+ cells was achieved in 21/27 (80%) patients of the 1 x 10 microg group and in 21/22 (95%) patients of the 2 x 5 microg/kg group with a median of two aphereses (range, 1-4). None in the 10 microg/kg group, but 6/22 (28%) patients in the 2 x 5 microg/kg group required only one apheresis procedure, resulting in fewer apheresis procedures in the 2 x 5 microg/kg group (mean, 1.8 vs 2.3, P = 0.01). These results demonstrate that priming with 10 microg/kg G-CSF alone is well tolerated and effective in mobilizing sufficient numbers of CD34+ cells in breast cancer patients and provide prompt engraftment after CTM high-dose chemotherapy. G-CSF given 5 microg/kg twice daily (2 x 5 microg) leads to a higher harvest of CD34+ cells and required fewer apheresis procedures than when given 10 microg/kg once daily (1 x 10 microg). (+info)Optimal timing for processing and cryopreservation of umbilical cord haematopoietic stem cells for clinical transplantation. (6/1207)
Some of the factors that may influence the number and quality of cord blood haematopoietic progenitor cells available for transplantation have been investigated including site of collection, delayed processing after collection and cryopreservation protocol. We used the granulocyte-macrophage progenitor (CFU-GM) and erythroid burst-forming unit (BFU-E) assays to quantify progenitors. The capacity of CFU-GM to produce secondary colonies was used as a measure of progenitor cell quality. We found that: (1) there were no significant differences in total nucleated cells (TNC), mononuclear cells (MNC), CFU-GM or BFU-E numbers in paired specimens from the umbilical vein or veins at the base of the placenta. The potential of the CFU-GM to produce secondary colonies from the two sites was similar; (2) storing cord blood at room temperature or at 4 degrees C resulted in a significant reduction in progenitor cell numbers beyond 9 h; and (3) cryopreservation following either controlled rate freezing or passive cooling reduced MNC numbers, viability and CFU-GM survival insignificantly but the potential of CFU-GM to produce secondary colonies was significantly reduced post cryopreservation (P = 0.04). We conclude that the yield of CB progenitor cells is not affected by the site of collection, but is adversely affected by delays between collection and cryopreservation. Furthermore, cryopreservation reduced the CFU-GM potential to produce secondary colonies. Measures of progenitor cell quality as well as quantity may be relevant to assessing CB blood collections. (+info)Ultrasound study of heel to calcaneum depth in neonates. (7/1207)
AIM: To investigate whether it would be safe to extend the currently recommended area of sampling to the whole heel in neonates. METHODS: Eighty newborn infants were studied, weight range 0.56 to 4.34 kg, gestation 24 to 42 weeks. Ultrasound scanning was used to measure the shortest distance between the skin and the perichondrium of the calcaneum. RESULTS: The shortest depth of perichondrium was in the centre of the heel and ranged from 3 to 8 mm. In 78 of the 80 infants the distance was 4 mm or more. There was a small but significant positive correlation with weight. CONCLUSIONS: Standard automated lancets for preterm use that puncture to a depth of 2.4 mm may be safely used anywhere over the plantar surface of the heel. The posterior aspect of the heel should be avoided. Reducing the density of heel pricks should reduce the associated pain. (+info)Evaluation of renal function from 99mTc-MAG3 renography without blood sampling. (8/1207)
To develop a camera-based method for evaluating renal function with 99mTc-mercaptoacetyltriglycine (MAG3), we examined the relationship between various renogram parameters and 99mTc-MAG3 clearance. METHODS: Twenty-one patients underwent renal scintigraphy with 99mTc-MAG3. Eighty 3-s frames were obtained after the bolus injection of 250 MBq tracer, followed by the collection of 52 30-s frames. Regions of interest were drawn for the kidneys, perirenal background areas and subrenal background areas, and background-subtracted renograms were generated. Renal accumulation at 0.5-1.5, 0.5-2, 1-2, 1-2.5 and 1.5-2.5 min after tracer arrival in the kidney was calculated as area under the background-subtracted renogram, and percent renal uptake was obtained after correction for soft-tissue attenuation and injected dose. The slope of the renogram was determined for the same segments used in calculating area under the renogram, and slope index was computed as slope corrected for attenuation and injected dose. Percent renal uptakes and slope indices were correlated by linear regression analysis with 99mTc-MAG3 clearance measured using a single blood sampling method. RESULTS: Among the values of percent renal uptake, the value obtained at 1.5-2.5 min using the perirenal background correlated best with 99mTc-MAG3 clearance. The slope index at 0.5-1.5 or 0.5-2 min using the subrenal background provided better accuracy than percent renal uptake for predicting clearance. There were no substantial differences in the relative function of the right kidney between the methods using percent renal uptake and slope index. CONCLUSION: 99mTc-MAG3 clearance can be assessed with acceptable accuracy by a camera-based method. The method based on the slope of the renogram may replace the one based on the area under the renogram in evaluating renal function from 99mTc-MAG3 renograms. (+info)The symptoms of chlamydia infections can vary depending on the location of the infection. In genital infections, symptoms may include:
* Discharge from the penis or vagina
* Painful urination
* Abnormal bleeding or spotting
* Painful sex
* Testicular pain in men
* Pelvic pain in women
In eye infections, symptoms can include:
* Redness and swelling of the eye
* Discharge from the eye
* Pain or sensitivity to light
In respiratory infections, symptoms may include:
* Cough
* Fever
* Shortness of breath or wheezing
If left untreated, chlamydia infections can lead to serious complications, such as pelvic inflammatory disease (PID) in women and epididymitis in men. Chlamydia infections can also increase the risk of infertility and other long-term health problems.
Chlamydia infections are typically diagnosed through a physical examination, medical history, and laboratory tests such as a nucleic acid amplification test (NAAT) or a culture test. Treatment for chlamydia infections typically involves antibiotics, which can effectively cure the infection. It is important to note that sexual partners of someone with a chlamydia infection should also be tested and treated, as they may also have the infection.
Prevention methods for chlamydia infections include safe sex practices such as using condoms and dental dams, as well as regular screening and testing for the infection. It is important to note that chlamydia infections can be asymptomatic, so regular testing is crucial for early detection and treatment.
In conclusion, chlamydia is a common sexually transmitted bacterial infection that can cause serious complications if left untreated. Early detection and treatment are key to preventing long-term health problems and the spread of the infection. Safe sex practices and regular screening are also important for preventing chlamydia infections.
CMV infections are more common in people with weakened immune systems, such as those with HIV/AIDS, cancer, or taking immunosuppressive drugs after an organ transplant. In these individuals, CMV can cause severe and life-threatening complications, such as pneumonia, retinitis (inflammation of the retina), and gastrointestinal disease.
In healthy individuals, CMV infections are usually mild and may not cause any symptoms at all. However, in some cases, CMV can cause a mononucleosis-like illness with fever, fatigue, and swollen lymph nodes.
CMV infections are diagnosed through a combination of physical examination, blood tests, and imaging studies such as CT scans or MRI. Treatment is generally not necessary for mild cases, but may include antiviral medications for more severe infections. Prevention strategies include avoiding close contact with individuals who have CMV, practicing good hygiene, and considering immunoprophylaxis (prevention of infection through the use of immune globulin) for high-risk individuals.
Overall, while CMV infections can be serious and life-threatening, they are relatively rare in healthy individuals and can often be treated effectively with supportive care and antiviral medications.
Bacteremia can occur when bacteria enter the bloodstream through various means, such as:
* Infected wounds or surgical sites
* Injecting drug use
* Skin infections
* Respiratory tract infections
* Urinary tract infections
* Endocarditis (infection of the heart valves)
The symptoms of bacteremia can vary depending on the type of bacteria and the severity of the infection. Some common symptoms include:
* Fever
* Chills
* Headache
* Muscle aches
* Weakness
* Confusion
* Shortness of breath
Bacteremia is diagnosed by blood cultures, which involve collecting blood samples and inserting them into a specialized container to grow the bacteria. Treatment typically involves antibiotics and supportive care, such as intravenous fluids and oxygen therapy. In severe cases, hospitalization may be necessary to monitor and treat the infection.
Prevention measures for bacteremia include:
* Practicing good hygiene, such as washing hands regularly
* Avoiding sharing personal items like toothbrushes or razors
* Properly cleaning and covering wounds
* Getting vaccinated against infections that can lead to bacteremia
* Following proper sterilization techniques during medical procedures
Overall, bacteremia is a serious condition that requires prompt medical attention to prevent complications and ensure effective treatment.
Symptoms of ehrlichiosis typically begin within one to two weeks after the tick bite and may include fever, headache, muscle pain, joint pain, and rash. In severe cases, the infection can spread to the bloodstream and cause more serious complications, such as respiratory distress, liver failure, and kidney failure.
Ehrlichiosis is diagnosed through a combination of physical examination, medical history, and laboratory tests, including a polymerase chain reaction (PCR) test to detect the bacterial DNA in the blood. Treatment typically involves antibiotics, such as doxycycline or azithromycin, which are effective against the bacteria that cause ehrlichiosis.
Prevention of ehrlichiosis primarily involves avoiding tick habitats and using tick-repellent clothing and insecticides to prevent tick bites. Early detection and treatment of ehrlichiosis can help reduce the risk of serious complications and improve outcomes for infected individuals.
These cells are typically small and irregular in shape and may have different surface markers than normal cells. They can travel through the bloodstream and potentially establish new tumors in other parts of the body. The presence of NCCs in the blood can be an early sign of cancer metastasis and can provide important diagnostic and prognostic information.
NCCs can be detected using various techniques, such as the CellSearch system, which uses a combination of magnetic and fluorescent markers to capture and identify CTCs in the blood. The detection and characterization of NCCs are becoming increasingly important in the management of cancer patients, particularly those with solid tumors like breast, prostate, and colorectal cancer.
Neoplastic cells circulating can be used for various purposes, including:
1. Diagnosis: The presence of NCCs in the blood can help confirm a cancer diagnosis and identify specific types of cancer.
2. Prognosis: The number and characteristics of NCCs can provide information about the aggressiveness of the cancer and the likelihood of metastasis.
3. Monitoring treatment response: The presence or absence of NCCs in the blood during treatment can indicate whether the therapy is effective or not.
4. Detection of minimal residual disease (MRD): NCCs can be used to detect small numbers of cancer cells that may remain after treatment, which can be an indicator of potential relapse.
5. Liquid biopsy: NCCs can be analyzed for genetic mutations and other molecular markers, providing valuable information for personalized medicine.
HIV (human immunodeficiency virus) infection is a condition in which the body is infected with HIV, a type of retrovirus that attacks the body's immune system. HIV infection can lead to AIDS (acquired immunodeficiency syndrome), a condition in which the immune system is severely damaged and the body is unable to fight off infections and diseases.
There are several ways that HIV can be transmitted, including:
1. Sexual contact with an infected person
2. Sharing of needles or other drug paraphernalia with an infected person
3. Mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Blood transfusions ( although this is rare in developed countries due to screening processes)
5. Organ transplantation (again, rare)
The symptoms of HIV infection can be mild at first and may not appear until several years after infection. These symptoms can include:
1. Fever
2. Fatigue
3. Swollen glands in the neck, armpits, and groin
4. Rash
5. Muscle aches and joint pain
6. Night sweats
7. Diarrhea
8. Weight loss
If left untreated, HIV infection can progress to AIDS, which is a life-threatening condition that can cause a wide range of symptoms, including:
1. Opportunistic infections (such as pneumocystis pneumonia)
2. Cancer (such as Kaposi's sarcoma)
3. Wasting syndrome
4. Neurological problems (such as dementia and seizures)
HIV infection is diagnosed through a combination of blood tests and physical examination. Treatment typically involves antiretroviral therapy (ART), which is a combination of medications that work together to suppress the virus and slow the progression of the disease.
Prevention methods for HIV infection include:
1. Safe sex practices, such as using condoms and dental dams
2. Avoiding sharing needles or other drug-injecting equipment
3. Avoiding mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Post-exposure prophylaxis (PEP), which is a short-term treatment that can prevent infection after potential exposure to the virus
5. Pre-exposure prophylaxis (PrEP), which is a daily medication that can prevent infection in people who are at high risk of being exposed to the virus.
It's important to note that HIV infection is manageable with proper treatment and care, and that people living with HIV can lead long and healthy lives. However, it's important to be aware of the risks and take steps to prevent transmission.
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06/14/2021: Lab Alert: Sodium Citrate Blood Specimen Collection Tubes in Short Supply
Browsing Meeting reports by Subject "Blood Specimen Collection"
NOT-HL-13-174: Notice of Availability of Specimens from Two Blood Donor Biorepository Collections
Home Blood Test Kits, Home Blood Specimen Collection Kits
Use of filter paper for the collection and analysis of human whole blood specimens
Use of filter paper for the collection and analysis of human whole blood specimens - PubMed
Postmortem Blood Urine Specimen Kit | Evidence Collection Kits | Forensic Supplies | Sirchie
Self-collection of Blood Specimens in Clinical Trials
Subjects: Blood Specimen Collection - Digital Collections - National Library of Medicine Search Results
GP41Ed7: Collecting Diagnostic Venous Blood Specimens
NHANES 2013-2014 Laboratory Data Overview
Serum Calcium: Reference Range, Interpretation, Collection and Panels
Table 5 - Misdiagnosis of Clostridioides difficile Infections by Standard-of-Care Specimen Collection and Testing among...
Subjects: Blood Specimen Collection - Digital Collections - National Library of Medicine Search Results
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CBC With Platelet, No Differential | Diagnostic Testing | Clinical Laboratory
UGT1A1 Gene Polymorphism (TA Repeat) (17813X) | Rady Children's Hospital
Fecal Occult Blood Test - StatPearls - NCBI Bookshelf
Lipid Profile (Triglycerides): Reference Range, Interpretation, Collection and Panels
Specimen Collection Instructions For Surgeons - Pediatric Neurosurgery | UCLA Health
Specimen Collection and Transport Containers - Specimen Collection - Clinical Laboratory - Medical Supplies - Departments |...
Laboratory Testing Services Manual - Guidelines for Specimen Collection and Submission | Texas DSHS
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按主题浏览023rd session: Guam, 27 September - 5 October 1972
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Clinical Laboratory Core - NIDDK
Laboratory32
- This paradigm involves sending specimen collection devices directly to patients, who then collect their own blood specimen and send it to a laboratory for testing. (appliedclinicaltrialsonline.com)
- Most of the time a central laboratory sets up a study database, and creates specimen collection kits that are study, investigator, and visit specific, and include requisitions and shipping materials. (appliedclinicaltrialsonline.com)
- From there the processes diverge in that self-collection kits may be sent directly to a patient's home instead of an investigator or home care specialist, and patients take on the process of collecting, potentially processing, and shipping samples back to the laboratory. (appliedclinicaltrialsonline.com)
- Currently, most laboratory tests approved by regulatory authorities are primarily based on venous blood and not capillary blood used by the devices described above. (appliedclinicaltrialsonline.com)
- NHANES collects biological specimens (biospecimens) for laboratory analysis to provide detailed information about participants' health and nutritional status. (cdc.gov)
- After completing the 24-hour urine collection, participants were instructed to collect these two full voids at home in separate specimen cups and mail them back to the contract laboratory. (cdc.gov)
- Each MEC had a laboratory containing a bio-hood, complete blood count (CBC) and differential analyzer, two centrifuges, refrigerators, and freezers. (cdc.gov)
- The DSHS Laboratory routinely updates specimen submission forms. (texas.gov)
- New versions of updated specimen submission forms with pre-populated submitter information are mailed to active submitters of the DSHS Laboratory. (texas.gov)
- For more information on how to obtain DSHS Laboratory Specimen Submission Forms, including current samples of specimen submission forms and instructions, please visit the DSHS submission form information found at https://www.dshs.texas.gov/laboratory-services/laboratory-testing-services-manual-forms-laboratory-fee-schedule Note that the sample submission forms (with watermarks) found at the link above are not to be submitted with specimens. (texas.gov)
- An important contributing factor to specimen testing success at the DSHS Laboratory is receiving correctly labeled, satisfactory specimens from our submitters. (texas.gov)
- When an unsat specimen is identified, laboratory staff will notify the submitter and in certain cases request another specimen be submitted for testing. (texas.gov)
- The laboratory provides educational resources (such as this guidance) to submitters to maximize the number of testable specimens we receive. (texas.gov)
- More testable specimens arriving at the laboratory mean more prompt and accurate detection and diagnosis of diseases and disorders for Texans. (texas.gov)
- Appropriate shipping of the specimen to the laboratory for testing. (texas.gov)
- Please exercise care when submitting specimens to the laboratory and in requesting tests. (texas.gov)
- To request a copy of the Specimen Collection and Shipping Manifest form for urine and blood specimens, please contact the Emergency Response Branch's Incident Response Laboratory at [email protected]. (cdc.gov)
- A blood culture is a laboratory test to check for bacteria or other germs in a blood sample. (medlineplus.gov)
- Patel R. The clinician and the microbiology laboratory: test ordering, specimen collection, and result interpretation. (medlineplus.gov)
- The Laboratory performs extensive validation of all assays before conducting routine sample analyses of clinical specimens. (nih.gov)
- Additionally, the Laboratory works to reduce costs of assays by centralizing the purchase of common supplies used in specimen analyses and by taking advantage of bulk purchasing discounts. (nih.gov)
- The Laboratory recently purchased a new specimen-tracking database. (nih.gov)
- This web-based tool is customizable and provides quick, reliable, and accurate accounting for clinical specimens stored with the Clinical Laboratory Core. (nih.gov)
- Label all bottles with surname, forename, date of birth and hospital number, source and date of sample collection to ensure accurate identification of sample by laboratory. (epsom-sthelier.nhs.uk)
- A serum specimen should ideally accompany PCR test requests for any patient not recently tested in our laboratory. (sutterhealth.org)
- We can only bill the hospital, doctor or laboratory where the specimen originated. (sutterhealth.org)
- Please be informed that if patient's check does not clear or if credit card payment has been declined, the ordering physician/laboratory where specimens originated will be responsible for the charges. (sutterhealth.org)
- 11) reported that the preanalytical phase had 46-68% of the total laboratory errors, and most of those errors were encountered during blood sample collection. (who.int)
- In the preanalytical stage, venous blood collection is critical because it affects laboratory results. (who.int)
- Facilities should have procedures in place that track and support the timely arrival of newborn screening specimens to the contract laboratory. (sd.gov)
- Due to the impact of the COVID 19 pandemic in NS, Nova Scotia Health's Laboratory Services are required to ensure there is adequate physical distancing for blood collection services. (nshealth.ca)
- Specimens are drawn with a heel prick, and the blood spotted on a special filter paper collection kit which is sent to the laboratory for testing. (oregon.gov)
Serum13
- This Notice from the National Heart, Lung, and Blood Institute (NHLBI) is to announce the availability of specimens collected from two Retrovirus Epidemiology Donor Study population-based biorepository collections: the General Serum Repository (GSR) and General Leukocyte Plasma Repository (GLPR). (nih.gov)
- The GSR was collected between 1991 and 1994 and consists of serum from 508,151 blood donations. (nih.gov)
- We have found via correlation studies, that some analytes may require redefining specific reference ranges for capillary blood, serum, or plasma. (appliedclinicaltrialsonline.com)
- If the specimen cannot be analyzed within 1 hour, the preferred specimen is serum. (medscape.com)
- The specimen should be centrifuged, and the serum or plasma should be removed from the cells within 2 hours of collection. (medscape.com)
- Our specimen requirement for serological testing is 2ml [minimum 0.5, but this amount may be insufficient for repeat testing of serum. (sutterhealth.org)
- Please centrifuge the specimen, and if possible, send serum only. (sutterhealth.org)
- Serum specimens can be sent at ambient temperature as long as the sample is sent to us overnight. (sutterhealth.org)
- Can serum and PCR specimens be mailed/sent in the same bag? (sutterhealth.org)
- Why must I send the mother's serum along with the baby's specimen? (sutterhealth.org)
- Collect 2-3 ml of blood in a red top or serum separator tube. (trinitybiotech.com)
- If possible, separate serum from clot and place into white tube provided with Immco Diagnostics' collection kits. (trinitybiotech.com)
- B. Separate the serum by centrifugation at approximately 200 rcf within two (2) to three (3) hours after collection. (drugs.com)
Venipuncture1
- This standard provides procedures for the collection of diagnostic specimens by venipuncture, including line collections, blood culture collection, and venipuncture in children. (clsi.org)
Sterile3
- Female and male participants aged 14-59 were asked to self-collect a vaginal or penile specimen using a sterile swab. (cdc.gov)
- In the OR place a block of tissue encompassing gray and subcortical white matter (please provide as much as is feasible) from the area of pathology directly into a sterile specimen container filled with 60 mL of cold sterile Hibernate®-A (Life Technologies). (uclahealth.org)
- Place a block of tissue from the area of very involved brain and second block form the area no so involved, but part of the planned resection, into separate empty sterile specimen containers filled with 60 mL of cold sterile Hibernate®-A. (uclahealth.org)
Collect8
- This article focuses on devices that can potentially enable patients to collect their own blood in their homes for clinical trials. (appliedclinicaltrialsonline.com)
- The following devices require a lancet, or have a self-contained lancet, and finger prick to collect via a dried blood spot format. (appliedclinicaltrialsonline.com)
- A random half of those who completed the initial 24-hour urine collection were recruited to collect a second 24-hour urine specimen 3 to 10 days later. (cdc.gov)
- In 2014, participants who completed the initial 24-hour urine collection were also asked to collect another two urine specimens: a void in the evening and the first void the following morning. (cdc.gov)
- Collect a minimum of 5 mL of blood via arterial line or vein into a blood tube with containing anticoagulant (e.g. green-top heparin tube or purple-top EDTA-Citrate tube). (uclahealth.org)
- Collect Specimens. (cdc.gov)
- Following a chemical exposure incident, collect blood and urine samples for each adult involved. (cdc.gov)
- A. Collect whole blood without anticoagulant and allow it to clot at room temperature. (drugs.com)
Phlebotomy3
- The protocol included both home phlebotomy and the use of self-collection devices. (appliedclinicaltrialsonline.com)
- Blood samples will be collected by ordinary blood drawing (phlebotomy) or by apheresis, a procedure for collecting a larger quantity of blood cells or plasma than would be possible through simple blood drawing. (nih.gov)
- Phlebotomy is a technique of blood drawing in which the needle is temporarily inserted into a suitable vein (1). (who.int)
Samples10
- A full description of the GSR and GLPR studies and how to apply for samples online is available on the NHLBI Biologic Specimen and Data Repositories Information Coordinating Center ( BioLINCC ) website. (nih.gov)
- Through technological innovation there are several devices under development for potential self-collection of dried blood spot and liquid blood samples. (appliedclinicaltrialsonline.com)
- In some immunological methods, collection devices with liquid preservatives are used, and samples from patients can be collected by smearing the stools onto the card provided. (nih.gov)
- Samples should not be collected if blood is visible in the stools or urine (e.g., menstruation, active hemorrhoids, or urinary tract infection). (nih.gov)
- CDC/ATSDR is processing and analyzing blood and urine samples and will mail individual results to participants. (cdc.gov)
- Samples are processed within 1 hour of blood collection to ensure thermal preservation. (nih.gov)
- They may give urine, blood, and saliva samples. (nih.gov)
- The NIAID Vaccine Research Center is collecting blood samples from adults ages 18 years of age or older who are fully recovered from confirmed COVID-19 infection. (nih.gov)
- If you're sending multiples samples, please be sure to place PCR specimens in separate biohazard bags to avoid contamination. (sutterhealth.org)
- It calls for rigorous adherence to test procedures and guidelines to ensure patient safety and integrity of blood samples (3). (who.int)
Phlebotomist6
- Some kits require a phlebotomist for a blood collection. (directlabs.com)
- Technologies and solutions are under development to enable self-collection without the need of a phlebotomist or nurse home visit or a patient visit to an investigator site. (appliedclinicaltrialsonline.com)
- Participant's fasting status is assessed by the MEC phlebotomist prior to the blood draw. (cdc.gov)
- Blood was collected from participants aged 1 year and older by a phlebotomist at the MEC. (cdc.gov)
- Specimens should be collected by the medical officer requesting the test or an experienced and fully trained phlebotomist. (epsom-sthelier.nhs.uk)
- Five diverse blood collections by each phlebotomist were observed at each session. (who.int)
Temperature2
- however, if concurrent potassium testing is requested on the same specimen, the low temperature leads to a spurious increase in potassium within 1 hour of collection. (medscape.com)
- At what temperature should the specimens be sent? (sutterhealth.org)
Preparation3
- Collection, preparation and mailing instructions are included in the test kit. (directlabs.com)
- Be sure to carefully follow the preparation instructions before collecting specimen. (directlabs.com)
- The acquisition process involves preparation of tubes for blood draw to achieve the lowest levels of degradation. (nih.gov)
Patient4
- Over the past several years, and more recently due to the COVID-19 global pandemic, patient centric trial designs have accelerated specimen collection either at home via visiting nurses or phlebotomists, or at retail locations, like a pharmacy or a Quest Diagnostics patient service center. (appliedclinicaltrialsonline.com)
- Like home specimen collection, self-collection of specimens in clinical trials, sometimes referred to as patient-centric sampling, may make participation in clinical trials more convenient for patients. (appliedclinicaltrialsonline.com)
- Self-collection of blood specimens in clinical trials starts out like specimen collection at investigator sites in that a protocol is developed and patient burden is strongly considered. (appliedclinicaltrialsonline.com)
- Another option is for the patient to include a personal check or money order along with the specimen. (sutterhealth.org)
Sodium6
- The US is experiencing significant interruptions in the supply of sodium citrate blood specimen collection (light blue top) tubes because of an unprecedented increase in demand and the recent vendor supply challenges, due in part to a recall . (cdc.gov)
- Do not include sodium citrate (light blue top) tubes in routine collections of a variety of specimens at the time of other blood sampling or IV insertion. (cdc.gov)
- Limit allocation of 1.8mL sodium citrate (light blue top) tubes for difficult blood collections. (cdc.gov)
- 2- 10ml blood collection tubes containing 100 mg. of sodium fluoride and 20mg. (sirchie.com)
- Whole blood collected in an EDTA (royal blue-top), sodium heparin (green-top) or a lithium heparin (green-top) tube is also acceptable. (rchsd.org)
- Authorized sodium citrate blood specimen collection tubes are assigned the QPW product code. (fda.gov)
Handling1
- Specimen collection and handling for diagnosis of infectious diseases. (medlineplus.gov)
Tubes3
- Invert tubes several times to ensure that the anticoagulant mixes well with the blood. (uclahealth.org)
- Remember, blood tubes and urine cups cannot be shipped together in the same package. (cdc.gov)
- 1. Blood collection tubes. (drugs.com)
Stool5
- In clinical trials self-collection of DNA via saliva and cheek swabs, as well as stool self-collection are also relatively common. (appliedclinicaltrialsonline.com)
- Data are presented in descending order of Study stool specimen collected column. (cdc.gov)
- The fecal occult blood test (FOBT) is a diagnostic test to assess for hidden (occult) blood in the stool. (nih.gov)
- FIT uses antibodies to discern blood in the stool. (nih.gov)
- Before stool collection and testing, it is imperative to ensure that the FOBT card and developer are not beyond their expiration dates. (nih.gov)
Clinical3
- The Newborn Screening Quality Assurance Program provides an independent evaluation of filter papers approved by the Food and Drug Administration for the collection of blood for clinical tests. (nih.gov)
- Study design and protocol writing will need to be carefully considered to expand the use of self-collection in clinical trials where appropriate. (appliedclinicaltrialsonline.com)
- Prior to the surgery date the REBDTB will send a specimen collection package to the participating institution containing specimen collection containers, Hibernate-A media, consent forms, documentation of tissue bank approval by UCLA Institutional Review Board (IRB), specimen collection instructions, non-identifiable clinical data collection sheet and any other relevant information/materials. (uclahealth.org)
Procedure1
- Correct specimen collection procedure. (texas.gov)
Containers1
- Label the specimen containers with the appropriate anatomic area resected. (uclahealth.org)
EDTA1
- Whole blood in a Lavender top tube [EDTA]. (nationaljewish.org)
Routinely1
- Newborns routinely have specimens drawn for testing before discharge from the hospital. (oregon.gov)
Subjects1
- In normal subjects, the volume of blood lost from the gastrointestinal tract is 0.5 to 1.5 mL per day. (nih.gov)
Routine1
- This structure supports ongoing and routine specimen analyses, charging for the cost of supplies only. (nih.gov)
Pathology1
- Transport specimen to pathology reception. (epsom-sthelier.nhs.uk)
Anticoagulant1
- Gently invert all bottles as they are removed from the holder, to ensure blood and anticoagulant are mixed to avoid clotting. (epsom-sthelier.nhs.uk)
Phlebotomists2
- Please note phlebotomists do not take blood cultures blue - coagulation tests red - no anti-coagulant yellow - gel clot activator pink 7ml size - blood grouping and cross-matching purple 4.5ml size - full blood count grey - glucose. (epsom-sthelier.nhs.uk)
- We monitored 120 blood collections by 24 phlebotomists, 16 (66.7%) male, and 8 (33.3%) female, with a mean age of 31.1 years. (who.int)
Receipt2
- Upon receipt of the updated specimen submission forms, replace and destroy the older corresponding versions. (texas.gov)
- Report availability is within one week from the time of specimen receipt. (trinitybiotech.com)
Biospecimen collection1
- The biospecimen collection took place in the mobile examination center (MEC). (cdc.gov)
Drawn3
- The amount of blood drawn varied by age. (cdc.gov)
- The site where blood will be drawn is first cleaned with an antiseptic such as chlorhexidine. (medlineplus.gov)
- It contains information about the importance of newborn screening as well as the best time for the second specimen to be drawn (10-15 days). (oregon.gov)
Tube2
- What kind of collection tube is required? (sutterhealth.org)
- If separation facilities are not available, the blood can be sent in the tube used for collection. (trinitybiotech.com)
Whole blood4
- The GLPR was collected in 1994 and 1995 and consists of aliquots of plasma, and whole blood, frozen with or without DMSO, obtained from 147,915 blood donations. (nih.gov)
- Performance properties of filter paper devices for whole blood collection. (nih.gov)
- Whole blood specimens should be analyzed within 15-30 minutes of collection. (medscape.com)
- Offsite: Send whole blood Priority Overnight via FedEx and in a well insulated container on an ice pack. (nationaljewish.org)
Newborn2
- The program helps participating laboratories to evaluate and improve the quality of their newborn-screening testing efforts by providing quality control dried blood spot materials and proficiency-testing materials for the external evaluation of screening programs. (nih.gov)
- Quick delivery of newborn screening dried blood spot specimens is crucial. (sd.gov)
Centers1
- Specimens for both the GSR and the GLPR repositories were collected according to a statistical sampling plan designed to obtain donations that are representative of the five blood centers' racial/ethnic groups. (nih.gov)
Guidance1
- This guidance was developed to address the most frequently encountered reasons for specimen unsats. (texas.gov)
Container1
- The examining dentist instructed participants aged 14-69 to gargle and swish with mouthwash for 30 seconds and then spit into a specimen container. (cdc.gov)
Prepaid1
- Home test kits are mailed to you at no charge and most include a prepaid specimen return envelope with the exception of International Orders. (directlabs.com)
Send1
- How do I send the specimen? (sutterhealth.org)
Place2
- Place bottles in specimen bag and seal. (epsom-sthelier.nhs.uk)
- Place the dried specimen collection card inside the provided envelope and ship it by the contract laboratory's designated courier. (sd.gov)
Search1
- Results of search for 'su:{Blood specimen collection. (who.int)
Time2
Volumes1
- The specific device, and its regulatory status, the sample format (liquid or dried blood spot), approach to collection (lancet or device), location of collection (arm/thigh or finger), as well as the blood sample volumes required for the tests should be considered in developing the collection approach. (appliedclinicaltrialsonline.com)
Infections1
- With some infections, bacteria can be found in the blood only intermittently. (medlineplus.gov)
Instructions2
- Follow the CDC's instructions for how to package and ship specimens found on this website . (cdc.gov)
- Refer to the blood collection location information below for appointment booking instructions. (nshealth.ca)
Avoid contamination1
- To avoid contamination of the sample do not take blood from an arm containing a drip or transfusion. (epsom-sthelier.nhs.uk)
Undergo2
- Patients undergo collection of blood every 1-3 months during radium Ra 223 dichloride treatment. (clinicaltrials.gov)
- Participants may have only one sample collected or may be asked to undergo repeat sample collection procedures, depending upon the requirements of the research project. (nih.gov)
Sample collection2
- [8] If there is a delay between sample collection and analysis, false-negative results may be seen because of the degradation of the pseudoperoxidase activity of heme in moist feces. (nih.gov)
- Previously, medical technicians were responsible for blood sample collection, but in recent decades, this practice has changed and the responsibility is now shared with other health professionals (4). (who.int)
Tests5
- Donor screening and testing was performed according to blood center's standard operating procedures and included tests for anti-HIV (types 1 and 2 after March 1992), anti-HCV, anti-HTLV, HBsAg and anti-HBc, serologic testing for syphilis, and testing for ALT levels. (nih.gov)
- We offer a wide variety of important health and wellness blood chemistry tests. (directlabs.com)
- Therefore, we reserve the right to withdraw testing services from a submitter in cases of misuse or improper specimen submission since reliable tests cannot be performed on incorrect, inadequate, or substandard specimens. (texas.gov)
- Participants may have blood and urine tests. (nih.gov)
- The program tests more than 320,000 specimens representing more than 180,000 babies each year and is entirely supported by fees. (oregon.gov)
Needle1
- When the needle is inserted to draw blood, some people feel moderate pain. (medlineplus.gov)
Types2
- Collection procedures varied based on the specimen types. (cdc.gov)
- Other types of germs, such as a fungus or a virus, may also be found in a blood culture. (medlineplus.gov)
Dried blood spot2
- The Tasso device is available in both dried blood spot and liquid collection formats. (appliedclinicaltrialsonline.com)
- TAP, by Seventh Sense Biosystems, is available in a liquid collection format, and OneDrawTM from Drawbridge Health, is available in dried blood spot format. (appliedclinicaltrialsonline.com)
Participants2
- Participants aged 6 and older were asked to provide a full void of urine in the MEC using a specimen cup. (cdc.gov)
- Participants were scheduled to return to a urine study mobile examination center (UMEC, which was parked next to the regular NHANES MEC) for two visits, one to start their urine collection and a second to return their kits and finish their collection. (cdc.gov)
Fluid1
- In addition, liquid anticoagulants such as ACD fluid will dilute the specimen. (drugs.com)
Frozen1
- Specimen need not be refrigerated or frozen. (trinitybiotech.com)
Disorders1
- It includes information about screening practices, specimen collection, educational services, as well as more information about disorders. (oregon.gov)
NHLBI2
- In addition to NHLBAC members, the meeting included an ad hoc Board of External Experts (BEE), scientists with research expertise in National Heart, Lung, and Blood Institute (NHLBI) mission areas, who were recruited for this meeting as a special NHLBAC working group. (nih.gov)
- Dr. Gary H. Gibbons, Director of the National Heart, Lung, and Blood Institute (NHLBI), called the meeting to order at 12:02 p.m. (nih.gov)
Overnight1
- Specimens should be sent using an overnight courier such as FedEx or UPS. (sutterhealth.org)
Collecting1
- As lab personnel, you play a crucial role in response to chemical emergencies by collecting, packaging, and shipping specimens to confirm potential chemical exposures. (cdc.gov)
Saliva1
- Companies like Ancestry.com and 23andMe have helped make the self-collection of DNA via saliva relatively commonplace. (appliedclinicaltrialsonline.com)
Services2
- All blood collection services now require booked appointments. (nshealth.ca)
- Nova Scotia Health launched an in-home blood collection service due to impacts on public and private blood collection services in the province. (nshealth.ca)