Blood Protein Electrophoresis: Electrophoresis applied to BLOOD PROTEINS.Blood Proteins: Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.Vitelline Duct: The narrow tube connecting the YOLK SAC with the midgut of the EMBRYO; persistence of all or part of it in post-fetal life produces abnormalities, of which the commonest is MECKEL DIVERTICULUM.Paraproteinemias: A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.Paraproteins: Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.Blood Protein DisordersElectrophoresis, Cellulose Acetate: Electrophoresis in which cellulose acetate is the diffusion medium.Electrophoresis: An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current.Serum Albumin: A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.Bromcresol Green: An indicator and reagent. It has been used in serum albumin determinations and as a pH indicator.Electrophoresis, Capillary: A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992)Electrophoresis, Agar Gel: Electrophoresis in which agar or agarose gel is used as the diffusion medium.Monoclonal Gammopathy of Undetermined Significance: Conditions characterized by the presence of M protein (Monoclonal protein) in serum or urine without clinical manifestations of plasma cell dyscrasia.Electrophoresis, Polyacrylamide Gel: Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Immunoelectrophoresis: A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.Nephelometry and Turbidimetry: Chemical analysis based on the phenomenon whereby light, passing through a medium with dispersed particles of a different refractive index from that of the medium, is attenuated in intensity by scattering. In turbidimetry, the intensity of light transmitted through the medium, the unscattered light, is measured. In nephelometry, the intensity of the scattered light is measured, usually, but not necessarily, at right angles to the incident light beam.Immunoglobulin Light Chains: Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of light chains, kappa and lambda. Two Ig light chains and two Ig heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) make one immunoglobulin molecule.Immunoglobulin lambda-Chains: One of the types of light chain subunits of the immunoglobulins with a molecular weight of approximately 22 kDa.Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.Electrophoresis, Gel, Two-Dimensional: Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.gamma-Globulins: Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.Bence Jones Protein: An abnormal protein with unusual thermosolubility characteristics that is found in the urine of patients with MULTIPLE MYELOMA.Immunoglobulin kappa-Chains: One of the types of light chains of the immunoglobulins with a molecular weight of approximately 22 kDa.Electrophoresis, Gel, Pulsed-Field: Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.Bacterial Proteins: Proteins found in any species of bacterium.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Bacterial Typing Techniques: Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.DNA, Ribosomal: DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)Molecular Weight: The sum of the weight of all the atoms in a molecule.Electrophoresis, Microchip: A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.Electrophoresis, Disc: Electrophoresis in which discontinuities in both the voltage and pH gradients are introduced by using buffers of different composition and pH in the different parts of the gel column. The term 'disc' was originally used as an abbreviation for 'discontinuous' referring to the buffers employed, and does not have anything to do with the shape of the separated zones.Agammaglobulinemia: An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood.Blood DonorsMedical Laboratory Personnel: Health care professionals, technicians, and assistants staffing LABORATORIES in research or health care facilities.Laboratory Chemicals: Chemicals necessary to perform experimental and/or investigative procedures and for the preparation of drugs and other chemicals.Lipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Complement C3b Inactivator Proteins: Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Chromatography, Gel: Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.Complement Inactivator Proteins: Serum proteins that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is potentially dangerous for the host. The complement system is tightly regulated by inactivators that accelerate the decay of intermediates and certain cell surface receptors.Serum: The clear portion of BLOOD that is left after BLOOD COAGULATION to remove BLOOD CELLS and clotting proteins.Newfoundland and Labrador: Province of Canada consisting of the island of Newfoundland and an area of Labrador. Its capital is St. John's.Dissertations, Academic as Topic: Dissertations embodying results of original research and especially substantiating a specific view, e.g., substantial papers written by candidates for an academic degree under the individual direction of a professor or papers written by undergraduates desirous of achieving honors or distinction.Academic DissertationsLibraries, Digital: Libraries in which a major proportion of the resources are available in machine-readable format, rather than on paper or MICROFORM.Dog Diseases: Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.Nursing Research: Research carried out by nurses, generally in clinical settings, in the areas of clinical practice, evaluation, nursing education, nursing administration, and methodology.Education, Graduate: Studies beyond the bachelor's degree at an institution having graduate programs for the purpose of preparing for entrance into a specific field, and obtaining a higher degree.

Hemoglobin Providence. A human hemoglobin variant occurring in two forms in vivo. (1/477)

Hemoglobin Providence Asn and Hemoglobin Providence Asp are two abnormal hemoglobins which apparently arise from a single genetic change that substitutes asparagine for lysine at position 82 (EF6) in the beta chain of human hemoglobin. The second form appears to be thr result of a partial in vivo deamidation of the asparagine situated at position beta 82. Cellulose acetate and citrate agar electrophoresis of hemolysates from patients with this abnormality shows three bands. Globin chain electrophoresis at acid and alkaline pH shows three beta chains. These three chains correspond to the normal beta A chain and two abnormal beta chains. Sequence analysis indicates that the two abnormal chains differ from beta A at only position beta 82. In the two abnormal chains, the residue which is normally lysine is substituted either by asparagine or by aspartic acid. These substitutions are notable because beta 82 lysine is one of the residues involved in 2,3-diphosphoglycerate binding. Additionally, beta 82 lysine is typically invariant in hemoglobin beta chain sequences. Sequence data on the two forms of Hemoglobin Providence are given in this paper. The functional properties of these two forms are described in the next paper.  (+info)

Effects of a frequent apolipoprotein E isoform, ApoE4Freiburg (Leu28-->Pro), on lipoproteins and the prevalence of coronary artery disease in whites. (2/477)

Different isoforms of apoE modulate the concentrations of plasma lipoproteins and the risk for atherosclerosis. A novel apoE isoform, apoE4Freiburg, was detected in plasma by isoelectric focusing because its isoelectric point is slightly more acidic than that of apoE4. ApoE4Freiburg results from a base exchange in the APOE4 gene that causes the replacement of a leucine by a proline at position 28. Analysis of the allelic frequencies in whites in southwestern Germany revealed that this isoform is frequent among control subjects (10:4264 alleles) and is even more frequent in patients with coronary artery disease (21:2874 alleles; P=0.004; adjusted odds ratio, 3.09; 95% confidence interval, 1.20 to 7.97). ApoE4Freiburg affects serum lipoproteins by lowering cholesterol, apoB, and apoA-I compared with apoE4 (P<0.05). Our 4 apoE4Freiburg homozygotes suffered from various phenotypes of hyperlipoproteinemia (types IIa, IIb, IV, and V). In vitro binding studies excluded a binding defect of apoE4Freiburg, and in vivo studies excluded an abnormal accumulation of chylomicron remnants. ApoE4Freiburg and apoE4 accumulated to a similar extent in triglyceride-rich lipoproteins. HDLs, however, contained about 40% less apoE4Freiburg than apoE4. In conclusion, our data indicate that apoE4Freiburg exerts its possible atherogenic properties by affecting the metabolism of triglyceride-rich lipoproteins and HDL.  (+info)

Paraprotein estimation: a comparison of immunochemical and densitometric techniques. (3/477)

Paraproteins have been estimated by both immunochemical methods and densitometric analysis of electrophoretic strips. Correlation between the results obtained by these two methods, although generally good for assessing trends, varied between patients.  (+info)

Mass screening of newborn Swedish infants for alpha antitrypsin deficiency. (4/477)

During the first year of mass screening for alpha1 antitrypsin deficiency, 108,000 newborn Swedish infants were examined. The screening method and criteria used for selecting infants with alpha1 antitrypsin deficiency were reliable. The Pi Z phenotype occurred at a rate of one per 1,433 infants, and the PiZ allele frequency was .026. The Pi- allele was found in one Pi Z and one Pi S infant. The Pi- allele frequency probably was below .001.  (+info)

Red cell proteins. I. Two-dimensional mapping of human erythrocyte lysate proteins. (5/477)

Human erythrocyte lysate proteins were resolved into over 250 discrete spots by two-dimensional electrophoresis using isoelectric focusing in the first dimension and electrophoresis in the presence of sodium dodecyl sulfate, (SDS) in the second. The overwhelming excess of hemoglobin has made such analyses difficult in the past. However, with the ISO-DALT two-dimensional electrophoresis system, large numbers of red cell proteins can be mapped in the presence of hemoglobin. When hemoglobin and several other major proteins are removed by adsorption to DEAE-cellulose, additional minor components are seen, giving a total of over 275. With the use of purified preparations, the map positions of five cell enzymes or their subunits were determined: pyruvate kinase, catalase, glucose-6-phosphate dehydrogenase, hypoxanthine phosphoribosyltransferase, and carbonic anhydrase. The mapping techniques described complement and extend those traditionally used to find human red cell protein variants.  (+info)

Effect of overexpression of human apo A-I in C57BL/6 and C57BL/6 apo E-deficient mice on 2 lipoprotein-associated enzymes, platelet-activating factor acetylhydrolase and paraoxonase. Comparison of adenovirus-mediated human apo A-I gene transfer and human apo A-I transgenesis. (6/477)

Various mechanisms may contribute to the antiatherogenic potential of apolipoprotein A-I (apo A-I) and high density lipoproteins (HDLs). Therefore, the effect of adenovirus-mediated human apo A-I gene transfer or human apo A-I transgenesis on platelet-activating factor acetylhydrolase (PAF-AH) and arylesterase/paraoxonase (PON1) was studied in C57BL/6 and C57BL/6 apo E(-/-) mice. Human apo A-I transgenesis in C57BL/6 mice resulted in a 4.2-fold (P<0.0001) increase of PAF-AH and a 1.7-fold (P=0.0012) increase of PON1 activity. The apo E deficiency was associated with a 1.6-fold (P=0.008) lower PAF-AH and a 2.0-fold (P=0.012) lower PON1 activity. Human apo A-I transgenesis in C57BL/6 apo E(-/-)mice increased PAF-AH and PON1 activity by 2.1-fold (P=0.01) and 2.5-fold (P=0.029), respectively. After adenovirus-mediated gene transfer of human apo A-I into C57BL/6 apo E(-/-)mice, a strong correlation between human apo A-I plasma levels and PAF-AH activity was observed at day 6 (r=0.92, P<0.0001). However, PON1 activity failed to increase, probably as a result of cytokine-mediated inhibition of PON 1 expression. In conclusion, this study indicates that overexpression of human apo A-I increases HDL-associated PAF-AH activity. PON1 activity was also increased in human apo A-I transgenic mice, but not after human apo A-I gene transfer, a result that was probably related to cytokine production induced in the liver by the adenoviral vectors. Increased levels of these HDL-associated enzymes may contribute to the anti-inflammatory and antioxidative potential of HDL and thereby to the protection conferred by HDL against atherothrombosis.  (+info)

Thalassaemia in northern Liberia. A survey in the Mount Nimba area. (7/477)

A population survey in northern Liberia showed an average incidence of 9 percent of beta-thalassaemia trait. There was considerable tribal variation, the highest rates being mainly found in tribes having a low incidence of Hb S. A single example of deltabeta-thalassaemia trait was also found; the incidence of delta-chain variants was 1.8 percent. The effect of malaria on Hb A2 levels was investigated but appeared to be negligible. The problems of beta-thalassaemia and Hb S occurring in the same population are discussed. It is considered that, although made on a local sample, the results of this survey indicate a high incidence of beta-thalassaemia trait elsewhere in Liberia and that this is a suitable are for investigations of linkage at beta- and delta-chain loci. No conclusion is at present possible from the data on the presence of alpha-thalassaemia although 10 percent of neonates were found to have increased levels of Hb Barts.  (+info)

Haemoglobin Lepore Boston and elliptocytosis in a family of Indonesian-German ancestry. (8/477)

A family is presented in which Hb Lepore Boston was found in six individuals over three generations. The gene must have had its origin either in Java (Indonesia) or in what is now the Federal Republic of Germany. The haemoglobin was characterized by amino-acid analysis of the six tryptic peptides that have a different composition in the beta- and the delta-chain. The ratio of glycine to alanine in position 136 of the fetal haemoglobin, which was somewhat raised in the Hb Lepore carriers, averaged 31:39. In addition an elliptocytosis gene was found, which was inherited independently from Hb Lepore; the simultaneous presence of elliptocytosis in three family members did not seem to aggravate the mild anaemia caused by Hb Lepore.  (+info)

*Peroxiredoxin 2

1994). "Plasma and red blood cell protein maps: update 1993". Electrophoresis. 14 (11): 1223-31. doi:10.1002/elps.11501401183. ... 1994). "Purification and characterization of thiol-specific antioxidant protein from human red blood cell: a new type of ... The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T- ... This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of ...

*PRDX6

1994). "Plasma and red blood cell protein maps: update 1993". Electrophoresis. 14 (11): 1223-31. doi:10.1002/elps.11501401183. ... The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional ... 1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis. 13 ( ... Peroxiredoxin-6 is a protein that in humans is encoded by the PRDX6 gene. It is a member of the peroxiredoxin family of ...

*Thymoma

These include: full blood count, protein electrophoresis, antibodies to the acetylcholine receptor (indicative of myasthenia), ... with a very small risk of pneumomediastinum or mediastinitis and an even-lower risk of damaging the heart or large blood ...

*Tolosa-Hunt syndrome

These tests include a complete blood count, thyroid function tests and serum protein electrophoresis. Studies of cerebrospinal ...

*Alpha-1 antitrypsin

On electrophoresis, the protein component of the blood is separated by electric current. There are several clusters, the first ... The term alpha-1 refers to the protein's behavior on protein electrophoresis. ... As protein electrophoresis is imprecise, the A1AT phenotype is analysed by isoelectric focusing (IEF) in the pH range 4.5-5.5, ... Therapeutic concentrates are prepared from the blood plasma of blood donors. The US FDA has approved the use of four alpha-1 ...

*Monoclonal gammopathy of undetermined significance

The protein electrophoresis test should be repeated annually, and if there is any concern for a rise in the level of monoclonal ... check the blood for hypercalcemia and deterioration in renal function, check the urine for Bence Jones protein and perform a ... serum protein electrophoresis). Although patients with MGUS have sometimes been reported to suffer from Small Fiber Neuropathy ... is a condition in which an abnormal immunoglobin protein (known as a paraprotein) is found in the blood during standard ...

*Microfluidics

... blood. A drawback of DNA and protein arrays is that they are neither reconfigurable nor scalable after manufacture. Digital ... 2009). "Two-Dimensional Electrophoresis in a Chip". Lab-on-a-Chip Technology: Biomolecular Separation and Analysis. Caister ... blood cell separation, protein analysis, cell manipulation and analysis including cell viability analysis and microorganism ... Similar to a DNA microarray, a protein array is a miniature array where a multitude of different capture agents, most ...

*Antibody microarray

Jiang and colleagues illustrated nicely the correlation between array protein expression in two different blood preparations: ... Ekins RP (September 1998). "Ligand assays: from electrophoresis to miniaturized microarrays". Clin. Chem. 44 (9): 2015-30. PMID ... studying yeast protein kinases, analyzing autoimmune antibodies, and examining protein-protein interactions. The first approach ... "Protein expression profiling by antibody array analysis with use of dried blood spot samples on filter paper". Journal of ...

*Transthyretin

TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and ... TTR was originally called prealbumin (or thyroxine-binding prealbumin) because it ran faster than albumin on electrophoresis ... Less than 1% of TTR's T4 binding sites are occupied in blood, which is taken advantage of below to prevent TTRs dissociation, ... Preventing plaque formation is thought to enable a cell to rid itself of this otherwise toxic protein form and, thus, help ...

*Gel electrophoresis of proteins

In medicine, protein electrophoresis is a method of analysing the proteins mainly in blood serum. Before the widespread use of ... Discontinuous native protein gel electrophoresis Protein purification facility Educational resource for protein electrophoresis ... Protein electrophoresis is a method for analysing the proteins in a fluid or an extract. The electrophoresis may be performed ... SDS polyacrylamide gel electrophoresis (in short: gel electrophoresis, PAGE, or SDS-electrophoresis), free-flow electrophoresis ...

*Clone (B-cell biology)

... measured in a serum protein electrophoresis test or peripheral blood flow cytometry. Such an expansion is said to be " ...

*Serum protein electrophoresis

Electrophoresis is a laboratory technique in which the blood serum (the fluid portion of the blood after the blood has clotted ... Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins ... Fibrinogen, a beta-2 protein, is found in normal plasma but absent in normal serum. Occasionally, blood drawn from heparinized ... Fibrinogen, a beta-2 protein, is found in normal plasma but absent in normal serum. Occasionally, blood drawn from heparinized ...

*Protein precipitation

"Quantitative validation of different protein precipitation methods in proteome analysis of blood platelets". Electrophoresis. ... P is a protein-protein interaction coefficient, a is a protein-polymer interaction coefficient and x = ( μ i − μ i 0 ) R T {\ ... For example, in the biotechnology industry protein precipitation is used to eliminate contaminants commonly contained in blood ... This increases the protein-protein interactions and enhances precipitation. For the specific case of polyethylene glycol, ...

*Blood proteins

... haemoglobin is not a blood protein, as it is carried within red blood cells, rather than in the blood serum. Serum albumin ... All blood proteins are synthesized in liver except for the gamma globulins. Separating serum proteins by electrophoresis is a ... The normal laboratory value of serum total protein is around 7 g/dL. Examples of specific blood proteins: Prealbumin ( ... Blood proteins, also termed plasma proteins or serum proteins, are proteins present in blood plasma. They serve many different ...

*Protein isoform

Typical examples of glycoproteins consisting of glycoforms are the blood proteins as orosomucoid, antitrypsin, and haptoglobin ... as in lectin affinity chromatography and lectin affinity electrophoresis. ... A protein isoform, or "protein variant" is a member of a set of highly similar proteins that perform the same or similar ... Each unique sequence produces a specific form of a protein. A set of protein isoforms may also result from a set of closely ...

*Clinical chemistry

Protein electrophoresis Urine protein Bilirubin; direct; indirect; total Aspartate transaminase (AST) Alanine transaminase (ALT ... Serum is the yellow watery part of blood that is left after blood has been allowed to clot and all blood cells have been ... Function Tests Creatinine Blood urea nitrogen Liver Function Tests Total protein (serum) Albumin Globulins A/G ratio (albumin- ... electrophoresis, and immunoassay. There are now many blood tests and clinical urine tests with extensive diagnostic ...

*List of MeSH codes (E01)

... blood glucose self-monitoring MeSH E01.450.150.100.110 --- blood protein electrophoresis MeSH E01.450.150.100.115 --- blood ... blood circulation time MeSH E01.370.370.130 --- blood flow velocity MeSH E01.370.370.140 --- blood pressure determination MeSH ... whole blood coagulation time MeSH E01.450.375.120 --- blood grouping and crossmatching MeSH E01.450.375.125 --- blood ... blood chemical analysis MeSH E01.450.150.100.100 --- blood gas analysis MeSH E01.450.150.100.100.600 --- oximetry MeSH E01.450. ...

*Glycophorin

A glycophorin is a sialoglycoprotein of the membrane of a red blood cell. It is a membrane-spanning protein and carries sugar ... After separation of red cell membranes by SDS-polyacrylamide gel electrophoresis and staining with periodic acid-Schiff ... It is heavily glycosylated (60%). Glycophorins are rich in sialic acid, which gives the red blood cells a very hydrophilic- ... In total, the glycophorins constitute ~2% of the total erythrocyte membrane protein mass. These proteins are also known under ...

*Globulin

... s can be distinguished from one another using serum protein electrophoresis. Globulins exist in various sizes. The ... Globulins, albumins, and fibrinogen are the major blood proteins. The normal concentration of globulins in human blood is about ... Vicilin and legumin, from peas and other legumes, function as protein storage within seeds. These proteins can cause allergic ... Being the heaviest, the gamma globulins are among the slowest to segregate in gél electrophoresis. The immunologically active ...

*Paraproteinemia

When a paraproteinemia is present in the blood, there will be a narrow band, or spike, in the serum protein electrophoresis ... Paraproteinemias may be categorized according to the type of monoclonal protein found in blood:[citation needed] Light chains ... "Characterization of antihistamine-human serum protein interactions by capillary electrophoresis". J Chromatogr A. 1147 (2): 261 ... Others may make blood too viscous to flow smoothly (usually with IgM pentamer macroglobulins), a phenomenon known as ...

*Free-flow electrophoresis

... protein isoforms, multiprotein complexes, peptides, organelles, cells, DNA origami, blood serum and nanoparticles exist. The ... Matrix free separation, ideal for conserving protein activity/protein complexes High resolution separation of protein complexes ... Free-flow electrophoresis (FFE), also known as carrier-free electrophoresis, is a matrix-free electrophoretic separation ... Description of free flow electrophoresis of the American Electrophoresis Society Patent description of the Free Flow ...

*Bence Jones protein

... which causes the protein to precipitate) and now by electrophoresis of concentrated urine. More recently, serum free light ... Blood. 97 (9): 2900-2. doi:10.1182/blood.V97.9.2900. PMID 11313287. Shaw GR (August 2006). "Nonsecretory plasma cell myeloma-- ... A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular ... The Bence Jones protein was described by the English physician Henry Bence Jones in 1847 and published in 1848. Bernier, G. M ...

*Myeloma protein

An excess in the blood is known as paraproteinemia. Paraproteins form a narrow band, or 'spike' in protein electrophoresis as ... Other terms for such a protein are M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the ... abnormally high blood viscosity ("thickness" of the blood), and kidney damage. The concept and the term paraprotein were ... Blood serum paraprotein levels of more than 30 g/L is diagnostic of multiple myeloma, according to the diagnostic criteria of ...

*Hypergammaglobulinemia

The name of the disorder refers to an excess of proteins after serum protein electrophoresis (found in the gammaglobulin region ... All that is known is that there is an excess of IgM in the blood, with normal levels of the other immunoglobulins. The exact ... The protein that is encoded by this gene is called Activation-Induced Cytidine Deaminase (AICDA) and functions as a DNA-editing ... When a person is homozygous for the mutation in the AICDA gene, the protein fails to function, and thus somatic hypermutation, ...

*Richard D. Smith

His most successful invention has been the combination of capillary electro-phoresis with mass spectrometry. By the end of the ... They've learned breast cancer leaves traces behind in the blood that doctors might exploit someday. Smith has led studies for ... Plasma proteome measurements potentially can provide the basis for discovery of protein biomarkers or signatures for virtually ... Smith was the recipient of one of these awards, for the development of capillary electrophoresis-mass spectrometry. Since the ...

*Fragmentation (cell biology)

1. Red blood cell fragmentation A fragmented red blood cell is known as a schistocyte and is generally the result of an ... This pattern of fragmentation can be used to detect apoptosis in tests such as a DNA laddering assay with gel electrophoresis, ... CAD is usually inhibited by another protein in the cell, called Inhibitor of caspase-activated DNase (ICAD). In order for ... "Red Blood Cell Fragmentation. Improved Detection and Identification of Causes." American Journal of Clinical Pathology 90.3 ( ...
Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma, a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy between a low albumin and a relatively high total protein. Unexplained bone pain, anemia, proteinuria, renal insufficiency, and hypercalcemia are also signs of multiple myeloma, and indications for SPE. Blood must first be collected, usually into an airtight vial or syringe. Electrophoresis is a laboratory technique in which the blood serum (the fluid portion of the blood after the blood has clotted) is applied to an acetate membrane soaked in a liquid buffer., to a buffered agarose gel matrix, or into liquid in a capillary tube, and exposed to an electric current to separate the serum protein components into five major fractions by size and electrical charge: ...
Description of disease Protein electrophoresis - serum. Treatment Protein electrophoresis - serum. Symptoms and causes Protein electrophoresis - serum Prophylaxis Protein electrophoresis - serum
China Med-L- Dycz-24en Protein Electrophoresis Cell, Find details about China Electrophoresis Cell, Protein Electrophoresis Cell from Med-L- Dycz-24en Protein Electrophoresis Cell - Guangzhou Med Equipment Co., Ltd.
Objective. To describe the effect of HIV serostatus on serum proteins, serum protein electrophoresis (SPEP) patterns and monoclonal bands. Setting. Inkosi Albert Luthuli Central Hospital, Durban. Design. Retrospective, anonymous analysis of routine laboratory results. Results. Monoclonal bands were not increased in HIV-positive patients, who were younger and had increased polyclonal and oligoclonal bands and total proteins when compared with HIV-negative patients.
Alpha globulins are serum proteins that have the most rapid migration during electrophoresis. This subgroup of globulins is divided into faster and slower alpha1 and alpha2-globulins.Proteins are the most abundant compounds in your serum. Amino acids are the building blocks of all proteins. In turn proteins are the building blocks of all cells and body tissues. They are the basic components of enzymes, many hormones, antibodies and clotting agents. Proteins act as transport substances for hormones, vitamins, minerals, lipids and other materials. In addition, proteins help balance the osmotic pressure of the blood and tissue.Medical Tests Analyzer labtest bloodtest What does the test result mean?
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... is one of Lonzas key applications. We offer a wide choice of precast gels and buffers for protein electrophoresis (SDS PAGE).
Protein Electrophoresis is ordered to evaluate disease categories as acute or chronic inflammation, liver disorder, hypogammaglobulinemia, and possible monoclonal gammopathies.
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Renal injury may result in excess excretion of protein, called proteinuria. Urine protein electrophoresis helps determine the type of kidney injury.
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Background: Albumin/Globulin ratio (AG) typically declines in HIV infection due to excess immunoglobulin production by hyperactive B-cells and improves with antiretroviral therapy (ART) but may not fully reverse. The significance of AG in earlier stages of HIV disease is unclear. We compared AG with levels of interleukin-6 (IL-6) and D-dimer, biomarkers associated with mortality in HIV infection, before and after ART initiation among participants in the U.S. Military HIV Natural History Study (NHS). Methods: 194 persons in the NHS, a cohort of US military personnel and beneficiaries living with HIV, were retrospectively studied. Frozen stored sera were used to measure levels of IL-6 and D-dimer with assays validated for serum at two time points: ≥6 months post-HIV seroconversion but prior to ART initiation, and ≥6 months post-ART with viral suppression (, 50 copies/ml) on two successive evaluations. Laboratory values were analyzed using Spearman s rank correlation and Mann-Whitney U test. ...
I was found to have an increased IgG protein level on a urinalysis my doctor recommended that I have an SPEP (Serum Protein Electrophoresis) done, maybe you should ask about having that test done and then go from there with your doctor regarding the results. Best wishes ...
A prospective study involving 77 neonatal calves was carried out to determine which factors in management, physical status and laboratory findings at time of presentation to the clinic might help to predict wether a calf shall die or survive. Calf history and physical examination where done using a standard protocol . At presentation blood samples were collected for blood gas analysis, hematology and biochemistry • Twenty four hours later after the calf had been rehydrated a blood sample was collected for serum protein electrophoresis Calves that died were taken for necropsy and histopathology, bacteriology and virology performed on standard range of tissues The calves that later died had significantly lower segmented neutrophils, serum total proteins, body temperature, and serum calcium level and higher serum phosphorus level. It was concluded that serum total protein and body temperature may help predict wether calves shall die or survive ...
Normally there is no protein, or only a small amount of protein in the urine. An abnormally high amount of protein in the urine can be a sign of many different disorders.. UPEP may be recommended to help determine the cause of protein in the urine. Or it may be done as a screening test to measure the various amounts of different types of proteins in urine. UPEP detects 2 types of protein: albumin and globulins. ...
Browse Sigma-Aldrichs SDS-PAGE to find products in Acrylamides, Buffers, Detergents, Gel Casting Reagents, Gel Cross-Linkers, Gel Loading Reagents, Ready-to Use Gels, Reducing Agents, TruPAGE Precast Gels, Urea
Hi I know that a dimeric protein will separate during SDS-PAGE, but is this dimer will separate in his two subunits when it is in his native form, during non-dissociating PAGE? Kind regards, Sahbi Ayari ...
If I remember correctly, my instructions were to stop taking them when I felt dizzy or if my blood pressure dropped below 110/70. That was/is my baseline anyhow. I didnt ever get that low, I was making 130/80 on meds with trace protein at 6 weeks. I still got to come off my meds though. I stopped them for three days and my bp stayed at that level. I was still spilling protein and the nephrologist said that he thought my bp would come down further on its own once that cleared up. It did. So Im thinking that you are well in the zone for getting rid of those meds. I felt like a little old lady filling my prescription.....[xx ...
The basic principle of western blot are protein electrophoresis and ELISA. Electrophoresis is a commonly used method for separating proteins on the basis ..
Assayed, liquid human serum based control for monitoring precision of cardiac profile testing and Protein Electrophoresis; bilevel MiniPak (2 x 1 mL)
This document is in three parts the first part deals with an evaluation of the IFE Core Groups Module 1 on IFE, the second is a range of case studies and field experiences on IFE and the third is a review of the management of malnutrition in infants , 6 months.. ...
Looking for online definition of NADH-methemoglobin reductase in the Medical Dictionary? NADH-methemoglobin reductase explanation free. What is NADH-methemoglobin reductase? Meaning of NADH-methemoglobin reductase medical term. What does NADH-methemoglobin reductase mean?
Improve efficiency with Bio-Rads 1-D and 2-D electrophoresis systems, gels, cells, standards, buffers, and reagents for protein electrophoresis and blotting.
We report a case of diffuse normolipemic plane xanthoma. A 63-year-old male suffered from multiple yellowish macular patches over face, trunk and extremities for 3 years. Histopathology of skin lesion showed foam cells in the dermis. Plasma cholesterol, triglyceride and lipoprotein were normal. However, serum protein electrophoresis and immunoelectrophoresis showed IgG-monoclonal gammopathy. There was no evidence of multiple myeloma after nearly 1 year follow-up. ..................More ...
Freiburg im Breisgau, or more commonly "Freiburg" is known as the "Jewel of the Black Forest." By German standards it is a major city in southwest Germany, situated on the edge of the Black Forest. When ordering train tickets and similar items online, be careful not to confuse Freiburg (im Breisgau) with Freiburg (an der Elbe) or Fribourg in Switzerland.
RMPSU : Supplies: Aliquot Tube, 5 mL (T465) Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube (T465) Specimen Volume: 50 mL Collection Instructions: 1. Collect a random urine specimen. 2. Aliquot specimen between containers. 3. Label specimens appropriately (60-mL urine bottle for protein electrophoresis and immunofixation and 5-mL tube for protein, total). Additional Information: 1. Random urine, no volume is required. 2. Refrigerate specimen during collection and send refrigerated.
Die Psychologie an der Universität Freiburg zeichnet sich durch hochstehende Forschung, ein reiches Lehrangebot auf Bachelor-, Master- und Postgraduierten-Niveau, sowie durch ihre Zweisprachigkeit aus. Das Departement bietet vollständige Studienprogramme auf Deutsch, Französisch und auch zweisprachig an, mit praktischen Ausbildungselementen bei sehr guter Betreuung in einem anregenden internationalen Klima. Master- und Doktoratsstudierende sind an Forschungsprojekten des Departements beteiligt, die eine breite Palette von Gebieten, die in zehn Forschungsabteilungen aufgeteilt sind. Wir laden Sie herzlich ein, unsere Webseite zu erkunden - oder besser noch: besuchen Sie uns in Freiburg! ...
The University of Freiburg works like a magnet on the many outstanding early-stage researchers who come to Freiburg to establish their own junior research groups.. ...
Investigations were conducted to detect serum protein variant systems in mice and to define their genetic control. Three systems were detected. A pair of codominant alleles at a locus in the second linkage group controls electrophoretically different transferrin types. An electrophoretic difference among inbred lines in the presence or absence of a prealbumin is controlled by a single autosomal locus without dominance. A serologically detected system is controlled by a single locus closely linked or identical to the H-2 locus in the ninth linkage group. The variant component seems to be an [alpha]-globulin of high molecular weight. The principal difference between serum types is quantitative; qualitative differences are not excluded. The serum component is not detectably related serologically to H-2 erythrocyte antigens. The effects of development, pregnancy and stress upon these serum components were studied. Using these three serum variants as markers, the sera of homologous radiation chimeras ...
Millie (photographed below) is working with Vikram Sharma, who runs our Proteomics facility, looking at the proteomes of both Hela and some stem cells. This also involves her working with cell culture, protein electrophoresis and bioinformatics. She writes, " I think the Nuffield Placement is good because it enables students to practice advanced techniques that are beyond and above the A level syllabus. It also offers insights into the applications of Biomedicine in the world today". ...
What are the components of an average, modern molecular biology lab? Equipment and space to perform basic microbiology, DNA and protein electrophoresis equipment and cell culture have been found in every lab space Ive worked in. So…could these functions be performed in your basement, with a very small budget for equipment and reagents? Im planning a series of posts on this topic.. ...
Relationship of stress and physical activity with psychological and physiological health in young children" 2013-2017 (Hauptantragstellerin PD Dr. J. Puder; Leiterin Projekt Relationship of stress and PA with psychological well-being in young children CHF 450000) unterstützt durch den Schweizerischen Nationalfonds; SNF-Nr.-CRSII3_147673/1 (insgesamt CHF 1800000 ...
Tropische Clubsounds bei Bomba Latina im Kagan, Indie-Folk mit Hello Piedpiper im Swamp oder der siebte Geburtstag des Slow Clubs. Was am Wochende sonst noch los ist, erf hrst du in der bersicht.
Pitched at a level suitable for teaching post-baccalaureate courses in the separation sciences this textbook presents a comprehensive survey of chromatographic and capillary electrophoretic techniques.Poole, Colin F. is the author of Essence of Chromatography, published 2002 under ISBN 9780444501998 and ISBN 0444501991. [read more] ...
Measurable monoclonal protein in the serum (for immunoglobin [Ig]G or IgM, ,= 1.0 g/dL using serum protein electrophoresis [SPEP]/immunofixation electrophoresis [IFE]; for IgA, an SPEP/IFE confirming the presence of a monoclonal IgA band plus a quantitative IgA level of ,= 750 mg/dL) OR measurable urine Bence Jones paraprotein (,= 500mg/24hrs) OR a measurable serum free light chain (FLC), defined as an involved FLC level of ,10 mg/dl, and a serum FLC ratio that is ...
High blood protein (hyperproteinemia) is an increase in the concentration of protein in the bloodstream. High blood protein is not a specific disease or condition in itself, but it might indicate you have a disease.. High blood protein rarely causes signs or symptoms on its own. But sometimes it is uncovered while youre having blood tests done as part of an evaluation for some other problem or symptom.. If your doctor discovers high blood protein during an evaluation, he or she may recommend additional tests to determine if there is an underlying problem.. A total protein test can determine whether you have high blood protein. Other more-specific tests, including serum protein electrophoresis (SPEP), can help determine the exact source, such as liver or bone marrow, as well as the specific protein type involved in your high blood protein levels. Your doctor may order an SPEP if he or she suspects you have a bone marrow disease.. ...
Therapeutic MAb use has expanded significantly in the last 5 years, and depending on their target or concentration, MAbs may impact the routine clinical testing of patients. The first report of such interference was published in 2010, when serum protein electrophoresis (SPEP) and immunofixation (IFE) were ordered on a multiple myeloma patient on MAb therapy with siltuximab, targeting IL-6 (7). RTX and vedolizumab (VEDO) are also visualized as a fuzzy small band on SPEP when measured at their peak, 1 to 2 days after MAb infusion, and an IgG kappa is identified in the gamma fraction on IFE (8). SPEP and IFE are ordered for a number of indications, including autoimmune/infectious diseases (polyclonal hypergammaglobulinemia), renal dysfunction (nephrotic proteinuria), and primary immunodeficiency (hypogammaglobulinemia), diseases for which treatment with a therapeutic MAb is becoming common. These tests are also the most important part of the diagnostic workup for patients with suspected plasma cell ...
A hemoglobin electrophoresis can help diagnose diseases involving abnormal hemoglobin production, and often is performed as part of newborn screening tests.
A hemoglobin electrophoresis can help diagnose diseases involving abnormal hemoglobin production, and often is performed as part of newborn screening tests.
Mote B. Normal serum protein values in newborn infants, determined by cellulose acetate electrophoresis. J Am Osteopath Assoc 1967;67(4):430. doi: https://doi.org/.. Download citation file:. ...
Hemoglobin electrophoresis and evaluation answers are found in the Guide to Diagnostic Tests powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Cavalli, sforza L.; Santachiara, S A.; Wang, L; Erdelyi, E; and Barchas, J, "Electrophoretic study of 5-hydroxytryptophan decarboxylase from brain and liver in several species." (1974). Subject Strain Bibliography 1974. 607 ...
Multiple Myeloma and Related Serum Protein Disorders is a practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner.
... are essential in protein electrophoresis. These gel tanks allow polyacrylamide gel electrophoresis or PAGE to be performed effectively. There are a range of vertical electrophoresis systems of different sizes and gel capacities depending on the users requirements in native and SDS-PAGE. The gel rigs come with electrophoresis plates, combs and spacers as detailed and most offer gel casting systems and a wide range of gel combs as options. Spare glass plates and gel spacers along with other electrophoresis accessories are also detailed in this section. ...
Can huffing be detected in blood or urine test - What possible diagnosis for the ff urine test report: sg 1.035 pH 8.0 blood trace protein 100mg/dl l.Est moderate nitride pos. And bacteria of 50-250? Abnormal urinalysis. Leukocytes, nitrates and bacteria in urine with dysuria will indicate urinary infection and usually treated with antibiotics.
After adjustments for glomerular filtration rate (GFR), levels of creatinine, cystatin C, and ß trace protein each remained directly associated with kidney failure but differed in their associations with mortality, according to a newly published study (J Am Soc Nephrol 2011 doi: 10.1681/ASN.2011070663). The findings add to the body of knowledge about how these markers contribute prognostic information beyond that reflected in GFR.
CCMB maintains and stocks about 6500 biochemicals for the ongoing research activities of the laboratory. The facility has a cold room (+4°C), two +4°C refrigerators, eight deep freezers (-20°C) and two ultra deep freezers (-70°C) for storage of chemicals as per the recommended storage conditions. However, the chemicals stable at room temperature are kept in a room (98 sq.mtrs plinth area) where temperature is maintained at 28°C. The stocks of fine biochemicals include amino acids, proteins, enzymes, purification kits and buffer reagents. In addition, stocks of restriction enzymes, immunology research kits for purification and detection of recombinant proteins, reagents for protein electrophoresis, PCR, RTPCR, DNA sequencing and synthesis and buffers, tissue culture ware, medium and medium supplements, gel electrophoresis and column chromatography materials, chemicals related to proteomics, and microarray analysis are also kept in the centralized facility. The requirement for these chemicals ...
Novex Tris-Glycine Plus Midi Protein gels are improved polyacrylamide gels based on traditional Laemmli protein electrophoresis technology, allowing the use of Laemmli sample and running buffers. The gels offer reproducible separation of a wide range of proteins into well-resolved bands. Novex Tris-
Novex Tris-Glycine Plus Midi Protein gels are improved polyacrylamide gels based on traditional Laemmli protein electrophoresis technology, allowing the use of Laemmli sample and running buffers. The gels offer reproducible separation of a wide range of proteins into well-resolved bands. Novex Tris-
The RunOne Electrophoresis System is a compact horizontal running unit with integrated power supply that is small enough to fit in the palm of your hand Its versatile design along with its partnership with the MultiCasters allow you the flexibility to run the gels you need and not just the gels you
dd class=first,,a href=http://2010.igem.org/Team:Freiburg_Bioware/Project/The_Adeno-associated Virus,Adeno-associated Virus,/a,,/dd ...
Last week I drove the one+ hours south to Moffitt Cancer Center for my official three month blood draw. Although my local medical oncologist had my M-protein tested a month back--and it showed no remaining M-spike--the in-house lab and on-site pathologist at Moffitt has been my primary source for lab work done since I moved. ...
Freiburg. Freiburger Drogenhilfe will ins Heroin-Programm Der Heroinersatzstoff Diamorphin wird möglicherweise von Mitte nächsten Jahres an in Freiburg an schwerstsuchtkranke Menschen ambulant verabreicht. (Badische Zeitung, 04.09.2009) http://www.badische-zeitung.de/freiburg/freiburger-drogenhilfe-will-ins-heroin-programm--19045707.html Schweiz. Bundesrat sieht Drogenpolitik in Gefahr Das Angebot der Krankenkassen sei massiv zusammenzustreichen, fordert der Basler SVP-Nationalrat. Der Bundesrat dagegen warnt vor hohen Folgekosten. Kommt nicht in Frage. Der Bundesrat lässt an seiner Haltung keinen Zweifel. Ohne Wenn und Aber stellt er sich gegen eine Streichung der Abgabe von Drogen aus der obligatorischen Grundversicherung. Genau dies aber fordert Jean Henri Dunant per Motion. Die Prämienexplosion der Krankenkassen erzwinge radikale Massnahmen, begründet der Basler SVP-Nationalrat. Der Bundesrat müsse im Gesundheitswesen endlich sämtliche Einsparungen vornehmen, die möglich seien, um ...
Allow serum to clot completely at room temperature (minimum: SST - 30 minutes and red top tubes - 60 minutes). Centrifuge and separate serum from cells within 1 hour of collection ...
Je surveille les choses, comme ça quand les gens reviendront, ils trouveront tout comme il faut. Mais je savais que cétait pas vrai. Ya rien à surveiller. Les gens nreviendront jamais. Je me balade comme ça, tout comme un pauvre fantôme de cimetière..." ...
Je surveille les choses, comme ça quand les gens reviendront, ils trouveront tout comme il faut. Mais je savais que cétait pas vrai. Ya rien à surveiller. Les gens nreviendront jamais. Je me balade comme ça, tout comme un pauvre fantôme de cimetière..." ...
Geocaching is a treasure hunting game where you use a GPS to hide and seek containers with other participants in the activity. Geocaching.com is the listing service for geocaches around the world.
Systemic risk refers to the risk that the financial system is susceptible to failures due to the characteristics of the system itself. The tremendous cost of this type of risk requires the design and implementation of tools for the efficient macroprudential regulation of financial institutions. We propose a novel approach to measuring systemic risk. Key to our construction is a rigorous derivation of systemic risk measures from the structure of the underlying system and the objectives of a financial regulator. The suggested systemic risk measures express systemic risk in terms of capital endowments of the financial firms. Their definition requires two ingredients: first, a random field that assigns to the capital allocations of the entities in the system a relevant stochastic outcome. The second ingredient is an acceptability criterion, i.e. a set of random variables that identifies those outcomes that are acceptable from the point of view of a regulatory authority. Systemic risk is measured by the
This 3 Tesla machine is located at the Dept. of Neuroradiology at the NeuroCenter. It is fully equipped with video projection, eye tracker, subject feedback devices and audio presentation. Time for research is on Tue, Thu and every second Fri.. Contact: Hansjoerg Mast ...
Scientists from the cluster of excellence BIOSS Centre for Biological Signalling Studies at the University of Freiburg and the Freiburg University Medical Center have shown that inhibiting the epigenetic regulator KDM4 might ...
Bionik / Biomimetik: insbesondere: - Bio-inspirierte Materialien, Strukturen und Oberflächen (z.B.: selbst-reparierende Materialien, selbst-adaptive Materialen, Haft- und Antihaft-Oberflächen, Dämpfungs- und Isolationsmaterialien, verzweigte und unverzweigte Faserverbundmaterialien) - Bionik und Architektur (z.B. bionische Fassadenverschattungen, bio-inspirierter Leichtbau und bio-inspirierte elastische Architektur, bionische Konzepte für energiesparende bzw. energieautarke Gebäude, lebende Bauwerke) - Methoden der Bionik (Vorgehensweise bei bionischen Projekten, insbesondere Optimierung des Abstraktions- und Übertragungsvorgangs von den biologischen Ideengebern zu den bio-inspirierten technischen Produkten) - Bionik und Nachhaltigkeit ...
Researchers in Freiburg, Germany have invented a new device that revolutionizes lab analysis - the portable mini-lab performs faster and works more efficiently than a traditional laboratory.
Kontext: Sammlung Willy Pragher I: Filmnegative Baden-Württemberg, Teil 1&gt;&gt; Freiburg alt [Ordner 150] &gt;&gt; Innenstadt, Neuburg, Herdern, Zähringen
Kontext: Sammlung Willy Pragher I: Filmnegative Baden-Württemberg, Teil 1&gt;&gt; Freiburg alt [Ordner 150] &gt;&gt; Innenstadt, Neuburg, Herdern, Zähringen
A bone marrow aspirate showed no abnormalities (4% plasma cells). Serum protein electrophoresis (Ciba Corning Diagnostic) revealed decreased γ-globulins, and serum immunoelectrophoresis (IEP; Ciba Corning) showed decreased IgG, IgA, and IgM and the presence of a faint λ arc with anodal bowing attributable to λ-Bence Jones protein (BJP). Quantification of the serum immunoglobulins (rate nephelometry; QM 300; Beckman) showed 5.17 g/L IgG (reference interval, 7.10-18.58 g/L), 0.62 g/L IgA (reference interval, 0.89-3.87 g/L), and 0.08 g/L IgM (reference interval, 0.46-2.26 g/L). The concentration of β2-microglobulin in his serum was 16.6 mg/L (reference interval, 1-2.4 mg/L). IEP of his urine (concentrated 50×; Fig. 1⇑ A) showed albumin, a very faint κ arc, and an intense λ arc with bowing at the anodal end (i.e., λ-BJP). The diagnosis of multiple myeloma, light-chain type, was considered, and a bone marrow biopsy performed 1 week later essentially showed replacement of the marrow cells by ...
Kyle, RA, Durie, BJ, Rajkumar, SV. "Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management". Leukemia. vol. 24. 2010. pp. 1121-1127. [Summary of the International Myeloma Group recommendations on the diagnosis, prognosis, and management of monoclonal gammopathy of unknown significance and smoldering multiple myeloma.]. Kyle, RA, Therneau, TM, Rajkumar, SV. "Prevalence of monoclonal gammopathy of undetermined significance". N Engl J Med. vol. 354. 2006. pp. 1362-1369. [Population-based study that used serum protein electrophoresis to ascertain the prevalence of monoclonal gammopathies in a large geographically defined population that is well representative of the white population of the United States.]. Landgren, O, Weiss, B. "Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: ...
Hemoglobin electrophoresis realised as a routine screening test on 1 500 gabonese individuals revealed the existence of a sickle cell abnormality n 24.40% cases (22.27% were AS heterozygotous and 2.1% were SS homozygotous). Bapounov and Fang ethnies appeared to be the most involved. The importance of such disturbance (I gabonese individual out of 4 is concerned) could justify the creation of Prenatal Counseling Centers mainly dealing with this genetic problem.
Multiple myeloma, a disease of elderly, is extremely rare in those about 30 years of age. A patient with MM diagnosed at age 27 is described. He was a male with a four-month history of back pain and later, hemurus and tibia pain persisting despite NSAIDS. X-rays had shown lytic lesions on lateral radiograph of the skull and the humerus. His ESR was 120 mm. Serum calcium was 125 mg/l and glomerular filtration rate at 25 ml/min. There was a beta2 peak in the serum protein electrophoresis. The Immunohistochemical examination demonstrated a strong reaction for the Lambda light chain in all tumor cells. Bence Jones protein was present in urine. Bone marrow biopsy confirmed the diagnosis of multiple myeloma. Our patient was treated with dexamethasone, zoledronic acid, cyclophosphamide and thalidomide with good evolution. Actually, he was proposed for stem cell transplantation. This report illustrated that multiple myeloma should be even evoked in young patients.
The Health Services Research Coordination Unit of the Medical Faculty of the Albert-Ludwigs-University Freiburg is one of five Coordination Units founded in 2011 by the Ministry of Science, Research and Arts Baden-Württemberg in consultation with the Ministry of Social Affairs and Integration in order to establish Health Services Research in Baden-Württemberg. The funding by the ministries has ended in April 2017, ever since the Coordination Unit is financed by own funds.. Further Coordination Units are situated in Heidelberg, Mannheim, Tübingen and Ulm.. The Coordination Unit Freiburg pursues the goal to coordinate comprehensive activities at the University Medical Center and at the University and link them with projects in Health Services Research in the Freiburg and Southern Baden area.. Our Coordination Unit offers consultation to all actors in Health Services Research in the Freiburg and southern Baden area concerning the planning, conducting, analysis and publication of their projects. ...
Oligoclonal bands (OCBs) are bands of immunoglobulins that are seen when a patients blood serum, or cerebrospinal fluid (CSF) is analyzed. Two methods of analysis are possible: (a) protein electrophoresis, a method of analyzing the composition of fluids, also known as "agarose gel electrophoresis/Coomassie Blue staining", and (b) the combination of isoelectric focusing/silver staining. The latter is more sensitive. For the analysis of cerebrospinal fluid, a patient has a lumbar puncture performed, which collects some of his or her cerebrospinal fluid. The blood serum can be gained from a clotted blood sample. Normally it is assumed that all the proteins that appear in the CSF, but are not present in the serum, are produced intrathecally (inside the CNS). Therefore, it is normal to subtract bands in serum from bands in CSF when investigating CNS diseases. OCBs are especially important for multiple sclerosis. In MS, normally only OCBs made of immunoglobulin G antibodies are considered, though ...
https://doi.org/10.18632/oncotarget.15162 Zhen Chen, Yingjie Shao, Hongwei Yao, Qianfeng Zhuang, Kun Wang, Zhaoyu Xing, Xianlin Xu, Xiaozhou He, Renfang Xu
Im Lt. Col. John Hunnicutt. I am an Officer in the Army Reserve Medical Corps, serving at Brooke Army Medical Center at Fort Sam Houston, Texas.. And some people ask me, says, well what do they have you doing? I said, well the exact same thing I do in the civilian world.. My specialty is pathology and transfusion medicine. I decided to ah, to serve in the Army Reserve Medical Corps for my love of science and my desire to help Soldiers. Its been a real privilege and honor to be a part of Brooke Army Medical Center and to work with some really wonderful colleagues and people that truly are selfless.. But I can tell you firsthand, it is as good as any academic medical center that Ive worked at previously.. My main ah focus is to work with the laboratory and work with the state-of-the-art equipment thats present at BAMC and been fortunate enough recently to bring a new hemoglobin electrophoresis system on line, which is state-of-the-art.. Its been a privilege and honor serving my country by ...
Gentaur molecular products has all kinds of products like :search , Molecular Innovations \ HUMAN PLASMA PROTEINS GC Globulin, Human Plasma, Mixed Type \ HGCG for more molecular products just contact us
Most tissue-damaging processes such as infections, inflammatory diseases and malignant neoplasms are associated with a major acute phase response of the C-reactive protein (CRP) and other acute reactants e.g. AAT, AAGP, C3C, C4 HAPT. The CRP response frequently precedes clinical symptoms, including fever. In normal healthy individuals CRP is a trace protein with a range up to 5 mg/L. After onset of an acute phase response the serum CRP concentration rises rapidly and extensively. Levels of up to thousand times the normal value are associated with severe stimuli such as myocardial infarction, major trauma, surgery or malignant neoplasm. CRP has a half-life of only a few hours, making it an ideal tool for clinical monitoring ...
I stumbled on this site out of a little bit of desperation. Heres my story: I had my 2nd baby 3/21 this year. My pregnancy was great, awesome bp readings the whole way (same as first). I had trace protein for the last several office visits, I think even +1 at one point but it went back down. Great, drug free delivery, happy baby... Then I went in for my first pp checkup at 8 weeks after. Bp was 140/100. Its been a whirlwind almost 5 weeks since of fear, hope, discouragement. Ive been to the ER twice. Ive been on atenolol and captopril which made me feel awful, then on to bystolic and enalapril low doses. Those were doubled after a few days. Then I saw a bp specialist after a couple more days and was switched to labetalol instead of bystolic. Im now up to 20 mg of enalapril 2x/day and 200 mg labetalol 3x/day and it just spiked back up to 187/115 tonight ...
The springtails (Collembola) species collected include Desoria klovstadi, Fresia grisea, Cryptopygus cisantarcticus, Gomphiocephalus hodgsoni, Antarctophorus sudpolaris, Biscoia subpolaris and Neocryptopygus nivicolis. The mite (Acari) species collected were Stereotydeus mollis and Nanorchestes spp. Some genetic work was completed on one species of nematode Scottnema lindsayae from Mt Kyffin Traditional, morphologically-based, taxonomic approaches for assessing biodiversity were combined with more recent molecular techniques (e.g. allozyme and DNA analyses) with individuals from each study site evaluated using protein electrophoresis, mtDNA and morphological analyses. Allozyme electrophoresis was used to determine genetic differences within and among populations. Genotype frequencies were recorded for each locus at each site. Detailed and quantitative observations were made on modes of dispersal through the use of windsocks, pitfall traps and stream drift nets. These analyses are designed to ...
EZBlue Coomassie Brilliant Blue G-250 colloidal protein stain improves protein electrophoresis results while significantly reducing staining time. Conveniently packaged, EZBlue requires no messy weigh-ups or additions of methanol or acid. As a colloidal stain, it reacts only with proteins, not the gel itself.
Cancer Monthly. Colon Cancer treatments. Biologic therapy. Albert-Ludwigs-University, Freiburg, Germany. Compare therapy differences, longest survival rates, toxicity, side effects, hospitals.
Sm-12 Speedmaster Pocket Pal Densitometer - Get the lowest price on Sm-12 Speedmaster Pocket Pal Densitometer, online at AllegroMedical.com.
Important note: Materials go out of date very quickly. If using this training material please ensure that material on IFE is in line with the most recent Operational Guidance on IFE, version 2.1, 2007. The IYCF-integrated course is available in this resource library see: HIV/IYCF: IYCF Counselling: An integrated course.. ...
Development of partial linearized density matrix (PLDM) propagation methods for nuclear and electronic dynamics using a one electron spin orbital representation and the fermion cartesian mapping hamiltonian. ...
The whole is more than the sum of its parts: At the heart of the University of Freiburg are its 11 faculties and 18 research centers, where the instruction and research take place. Whereas the faculties unite related fields of study, the research centers conduct interdisciplinary and interfaculty research projects. These institutions are complemented by the central service departments, which provide a range of university-wide services. The interplay between these parts makes up the excellent profile of the University of Freiburg.. ...
University of Freiburg, Faculty of Biology, Institute for Biology II, Botany / Plant Physiology, Schänzlestr. 1, D-79104 Freiburg, Germany, Web: The Seed Biology Place - www.seedbiology.de (K.O., A.V., D.J., G.L.-M ...
Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis. Gerboth S, Frittoli E, Palamidessi A, Baltanas FC, Mogjiborahman S, Rappsilber J, Giuliani C, Troglio F, Rolland Y, Pruneri G, Kreutmair S, Pallavicini I, Zobel M, Cinquanta M, Minucci S, Gomez C, Santos E, Illert AL, Scita G ...
Von der Brasilianischen Nacht im QU bis zu italienischem Techno von Dandi & Ugo im Stinnes Areal: Der Party- und Konzertfahrplan f r das Wochenende steht. Wie vergangene Woche legen wir euch die Dates am Freitag, Samstag und Sonntag ans Herz. Geht feiern! Zudem verlosen wir zweimal zwei G stelistenpl tze f r die YumYum-Party im Jazzhaus.
Introduced in Aschaffenburg (Bahnhof, Pompejanum), Augsburg, Bielefeld-Quelle (Ostwestfalendamm), Darmstadt, Donauwörth, Düsseldorf, Eisenfelden, Frankenberg, Freiburg (Dreisam, Messe), Holzwickede, Inzlingen, Kulmbach (alter Güterbahnhof), Lörrach-Stetten, Mainau, Mannheim, München (Donnersberger Brücke, Südbahnhof), Nettetal-Kaldenkirchen, Nürtingen, Springe, Stuttgart (Bad Canstatt, Travertinpark, Ueffeln, West, Wilhelma), Tittling, Tübingen (Innenstadt Parkhaus, Schloß), Ulm (Adlerbastei), Witten-Bommern, Witten-Heven ...
FRI0479 Serum Free Light Chains of Immunoglobulins Are Associated with Disease Activity in Systemic Sclerosis: A Prospective and Controlled Study ...
OBJECTIVE: We evaluated the diagnostic value of cerebrospinal fluid oligoclonal bands in individuals less than 18 years of age.. METHODS: In a nationwide population-based setting, we retrieved data on 2055 childrens oligoclonal band examination, including concordant cerebrospinal fluid biomarkers, during 1994 to 2017. Case ascertainment was by review of medical records and diagnostic codes. We used Fishers exact test to explore distribution differences of oligoclonal band positivity in acquired demyelinating syndromes (ADS) before and after age 12 years and calculated the sensitivity, specificity, positive predictive value, and negative predictive value of oligoclonal bands to distinguish ADS from the other diagnostic groups.. RESULTS: Median age at oligoclonal band examination was 15.2 years (range = 1.8 to 18.0), and 10% had presence of cerebrospinal fluid oligoclonal bands. Oligoclonal band positivity was the highest in ADS (52%), but it was age dependent: 21% in children with ADS before ...
Note: Patients with IgA myeloma in whom serum protein electrophoresis is deemed unreliable, due to co-migration of normal serum proteins with the paraprotein in the beta region, may be considered eligible as long as total serum IgA level is elevated above normal range.. b. Melanoma i. Subjects must have a confirmed prior diagnosis of melanoma. ii. Progressed after at least 2 therapy lines. iii. Subjects with BRAF mutant tumors should have received and progressed through, or are intolerant to, BRAF/MEK inhibitor therapy prior to enrollment iv. Patients must have measurable disease per RECIST 1.1 in order to allow assessment of an anti-tumor response.. c. Synovial Sarcoma or Myxoid/Round Cell Liposarcoma (MRCL) i. Subjects must have a confirmed prior diagnosis of synovial sarcoma or MRCL. ii. Patients with proven metastatic disease or surgically inoperable local recurrence that have failed first line treatment.. ...
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At a Glance Plasma cell myeloma is a bone marrow-based clonal plasma cell proliferation. It comprises 10-15% of hematopoietic neoplasms. It is typically diagnosed as a result of evaluations for anemia, renal failure, and/or bone lytic lesions. When serum or urine protein electrophoresis studies detect a monoclonal immunoglobulin (paraprotein, M-protein) secreted by these neoplasms, the…. ...
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Principles and Applications of Paper Electrophoresis. With a foreword by P.König. Elsevier Monographs Vol. 11. PDF By author Wunderly, Ch. last download was at 2017-10-23 44:11:42. This book is good alternative for Principles and applications of paper electrophoresis (Chemistry section). Download now for free or you can read online Principles and Applications of Paper Electrophoresis. With a foreword by P.König. Elsevier Monographs Vol. 11. book ...
Protein Electrophoresis. During the next five years, the immunoprotein testing market will undergo significant transformation. The changes will be caused by convergence of new and more stringent regulations; advances in diagnostic technologies, system engineering, automation, and IT; and intensifying competition. Some segments will start resembling commodity markets, where product positioning and cost per test are more critical than underlying technology. This evolving marketplace will create exciting opportunities for a variety of new instruments, reagent systems, and auxiliary products, such as specimen preparation devices, controls, calibrators and others.. 2015-2019 German Immunoprotein Diagnostic Testing Market: Hospitals, Commercial Labs, Physician Offices is a unique market and technology assessment designed to help current suppliers and potential market entrants identify and evaluate emerging opportunities and developed effective strategic responses. The study explores future trends; ...
1. Molecular Ecology (A J Baker). 2. General Molecular Biology (R E Carter).. 3. Polymerase Chain Reaction (T P Birt & A J Baker).. 4. Protein Electrophoresis (A J Baker).. 5. Solution DNA-DNA Hybridisation (A H Bledsoe & F H Sheldon).. 6. DNA Fingerprinting using minisatellite probes (R E Carter).. 7. Mitochondrial DNA (E Randi).. 8. Characterization and Evolution of Major Histocompatibility Complex (Mhc) Geners in Non-Model Organisms, with Examples from Birds (S V Edwards, J Nusser & J Gasper).. 9. DNA-fragment markers in plants (C Ritland & K Ritland).. 10. Microsatellites: Evolutionary and Methodological Background and Empirical Applications at individual, population and phylogenetic levels (K T Scribner & J M Pearce).. 11. Introns (V Friesen).. 12. Sex Identification using DNA markers (R Griffiths) ...
Automated dual capillary electrophoresis system with hydrodynamic injeciton for the concurrent determination of cations and anions. Analytica chimica acta, Vol. 841. pp. 77-83 ...
Biotechnology: In close cooperation with industrial partners we initiated functional genomics of Physcomitrella, identifying novel genes relevant to metabolic engineering and to abiotic stresses such as drought, salt and cold. Such moss genes are being directly transferred to crop plants to improve their performance. Transgenic Physcomitrella can be grown photoautotrophically in bioreactors. We work on the production of pharmaceutically relevant proteins in such cultures in co-operation with the university spin-off company greenovation Biotech, Freiburg. In addition to these successful industrial co-operations we are ready to establish new partnerships. As a university group our work is primarily science-driven. However, we strongly feel that our basic work is paid by tax-money and we, therefore, have the responsibility to transfer applicable know-how swiftly to the market ...
Get a report of the Borussia Monchengladbach vs. SC Freiburg 2011/12 German Bundesliga, 2011/2012 German Bundesliga football match.
The results of this study indicate that the GT can be used to quickly differentiate chronic from acute inflammatory disease in horses. The high proportion of test negatives of horses having acute inflammation indicates that horses with inflammatory disease and negative GT are likely to be acutely, rather than chronically, inflamed. Among GT positive horses, 77% were chronically inflamed as shown in Table 5. The GT was not reliable in predicting the blood concentration of fibrinogen in acute or chronic inflammatory diseases.. Useful clinical information could be obtained by dividing GT-times into categories (groups) as listed in Table 2[23, 24]. Comparison of category and respectively globulin concentration and albumin/globulin ratio within a category seemed to correlate, although this tendency was not statistically significant. This could be due to the small number of data points. A larger number of horses included in a future study like ours would probably eliminate this statistical ...
... (SFLC, kappa and lambda) are proteins produce by immune cells that are not part of whole (intact) antibodies. Lab tests measure free light chains in the blood and a kappa/lambda ratio to help diagnose multiple myeloma and related diseases.
Current criteria for differential diagnosis of multiple myeloma (MM), Monoclonal gammopathy of undetermined significance (MGUS), and smoldering multiple myeloma (SMM) are included in the 2003 guidelines by the International Myeloma Working Group (IMWG). An updated version was then published in 2014, highlighting the importance of serum free light chain (sFLC) detection, as well as the κ/λ ratio as excellent indicators of clonality. At present, two commercial assays for sFLC quantification are available: the Freelite™ assay and the N-Latex assay. The first was developed by The Binding Site based on a mixture of polyclonal antibodies directed against a variety of FLC epitopes. It may be run on a wide range of nephelometers, as well as on turbidimeters. The second method was developed by Siemens and runs exclusively on Siemens instruments. It employs a probe mixture of mouse monoclonal antibodies. The aim of our study was to evaluate sFLC measurement and calculated κ/λ ratio in 85 patients with
TY - JOUR. T1 - Erythrocyte alterations in hemoglobin H disease. AU - Szelényi, J.. AU - Lelkes, G.. AU - Horányi, M.. AU - Földi, J.. AU - Szász, I.. AU - Hollán, S.. PY - 1981. Y1 - 1981. N2 - This study on erythrocytes in hemoglobin H (Hb-H) disease reveals that unstable Hb-H is bound to membranes to a greater extent, especially when it forms methemoglobin or is precipitated as an inclusion body. The methemoglobin content of these erythrocytes is elevated in spite of a higher activity of NADH-methemoglobin reductase. The ATPase activity is doubled and ATP is presumably used for phosphorylation of membrane proteins, which leads to cross-linking of membrane proteins. This assumption could be supported by the observed decrease in non-electrolyte permeability, by increased binding of hemoglobin to the membrane, and polymerisation of membrane proteins detected by SDS-polyacrylamide gel electrophoresis. By means of electron microscopy, it could also be shown that the inclusion bodies are bound ...
Background== *Normal protein excretion 150mg/24 hours or 10mg/100mL *>3.5g/24h considered nephrotic range *Dipstick: more sensitive to albumin, less sensitive to Bence-Jones protein and globulins **"Trace" protein ≈ 10mg/100mL (i.e. upper limit of normal) ==Causes/Differential Diagnosis== ===Functional=== *Benign: [[fever]]/acute illness, cold exposure, orthostatic proteinuria, strenuous exercise, [[hypertension]] *[[CHF]], [[shock]] *[[Preeclampsia]]/[[eclampsia]]/[[HELLP]], [[acute fatty liver of pregnancy ===Renal=== *Tubular dysfunction *Glomerular disease (e.g. [[glomerulonephritis]], [[diabetes]], [[HIV]], [[SLE]], [[amyloidosis]], [[IgA nephropathy]] or membranous nephropathy) *[[Nephrotic syndrome]] *[[Pyelonephritis]] *[[Malignant hypertension]] *[[Alport syndrome]] ===Drugs=== *[[Aminoglycosides]], [[penicillin]s, [[amphotericin]], [[penicillamine]], [[deferasirox]] *[[NSAIDs]], gold *[[Chloral hydrate toxicity]] *[[Lead toxicity]] ===Protein overload=== Note: bence-jones globulins ...
Background: Black seed (Nigella sativa L.) in traditional medicine is well known that the chemical composition of the immune system with many applications in traditional medicine to fight the infection. This study investigated the effect of the plants role in the immune system and blood protein. Experimental: In this study male mice of Balb/c strain were divided into four groups tested. Control and experimental groups 1, 2 and 3, respectively, 50, 100 and 200 dose mg/Kg of the extract of Nigella sativa seed hydro alcoholic extract in 20 days and injected intraperitoneally received. At the end of the experiment, blood was taken for white cell count and blood protein electrophoresis was used. The data obtained with the SPSS software. Results and discussion: Studies suggest that the extracts of Nigella sativa in the groups are able to increase white blood cell count, protein and albumin, alpha 1 and 2 and the A/G. Industrial/Practical recommendation: According to the survey results appear in the

Protein Electrophoresis and Total Protein Blood TestProtein Electrophoresis and Total Protein Blood Test

Protein Electrophoresis is ordered to evaluate disease categories as acute or chronic inflammation, liver disorder, ... Electrophoresis, Serum, PE, Serum Protein Electrophoresis, SPES, UPEP; Lipoprotein Electrophoresis. Preparation. No special ... Serum protein electrophoresis uses an electrical field to separate the proteins in the blood serum into groups of similar size ... The serum protein electrophoresis (SPE) test measures specific proteins in the blood to help identify some diseases. Proteins ...
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Protein Electrophoresis Blood Test, Reflex to IFEProtein Electrophoresis Blood Test, Reflex to IFE

Proteins are substances made up of smaller building blocks called amino acids. They also carry a positive or a negative electrical charge, and they move in fluid when placed in an electrical field. They do many things in the body, including the transport
more infohttps://www.walkinlab.com/protein-electrophoresis-serum-with-reflex-to-ife-blood-test.html

Plasma protein fractions in healthy blood donors quantitated by an automated multicapillary electrophoresis systemPlasma protein fractions in healthy blood donors quantitated by an automated multicapillary electrophoresis system

... Larsson, ... The 2.5 and 97.5 percentiles for both the percentages of different peaks and the protein concentrations in the peaks are ... The Capillarys instrument is a reliable system for plasma protein analysis, combining advantages of full automation with high ... During the last decade, capillary electrophoresis (CE) has emerged as an important alternative to traditional analysis of serum ...
more infohttp://uu.diva-portal.org/smash/record.jsf?pid=diva2:49580

Blood protein and white blood cells in urine - Things You Didnt KnowBlood protein and white blood cells in urine - Things You Didn't Know

High levels of white blood cells in urine. What could that mean? Pyuria. White blood cells in urine usually are there because ... Blood protein and white blood cells in urine - ... Have your doctor order a serum protein electrophoresis blood ... Blood and protein: Blood (b) in your urine(u) is an abnormal finding. Protein (p) in your urine is abnormal when it is > 80 mg/ ... Need suggestions sporadic cloudy urine r/s kidney pain blood protein 8.1, urine protein 10mg, ESR 29mm all other blood and ...
more infohttps://www.healthtap.com/topics/blood-protein-and-white-blood-cells-in-urine

Blood SciencesBlood Sciences

... Sebia is the worlds leading provider of clinical protein electrophoresis equipment and reagents , Medical ... Blood Sciences. Sebia is the worlds leading provider of clinical protein electrophoresis equipment and reagents. Its systems ...
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Factitious sickle cell acute painful episodes: a secondary type of Munchausen syndrome.Factitious sickle cell acute painful episodes: a secondary type of Munchausen syndrome.

Blood Protein Electrophoresis. Diabetes Mellitus, Type 1 / complications. Emergency Medical Services. Epilepsy / complications ...
more infohttp://www.biomedsearch.com/nih/Factitious-sickle-cell-acute-painful/8948666.html

Isolation from human serum of an inactivator of bacterial lipopolysaccharide.Isolation from human serum of an inactivator of bacterial lipopolysaccharide.

... a protein--termed the lipopolysaccharide inactivator (LPS-I)--has been isolated from normal human serum. As a res ... Blood Protein Electrophoresis. Blood Proteins / isolation & purification*. Chromatography, Gel. Endotoxins / antagonists & ... 0/Alpha-Globulins; 0/Blood Proteins; 0/Endotoxins; 0/Hydroxyapatites; 0/Lipopolysaccharides; 0/Polysaccharides, Bacterial ... a protein--termed the lipopolysaccharide inactivator (LPS-I)--has been isolated from normal human serum. As a result of ...
more infohttp://www.biomedsearch.com/nih/Isolation-from-human-serum-inactivator/70173.html

Memorial University - Electronic Theses and Dissertations 2Memorial University - Electronic Theses and Dissertations 2

Biochemical genetics; Glycoproteins; Blood protein electrophoresis. * * Save to favorites. * Terrain classification using ...
more infohttp://collections.mun.ca/cdm/search/collection/theses2/searchterm/classes/field/all/mode/any/conn/and/cosuppress/

Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)

Categories: Blood Protein Electrophoresis Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
more infohttps://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Blood+Protein+Electrophoresis&parentid=4533&catid=4567

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Blood Protein Electrophoresis (2). Bone Marrow/*pathology (2) Diagnosis, Differential (2) Heavy Chain Disease/complications/* ... While serum protein electrophoresis (SPEP) is typically normal, immunofixation (IF) detects monoclonal mu IgH in polymers of ...
more infohttp://documents.irevues.inist.fr/handle/2042/68123/discover?rpp=10&filtertype_0=author&filtertype_1=subject&filter_0=Anderson%2C+Kenneth+C&filter_relational_operator_1=equals&filter_1=Leukaemia+Section&filter_relational_operator_0=equals&filtertype=subject&filter_relational_operator=equals&filter=Blood+Protein+Electrophoresis

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Blood Protein Electrophoresis (2). Bone Marrow/*pathology (2) Diagnosis, Differential (2) Heavy Chain Disease/complications/* ... While serum protein electrophoresis (SPEP) is typically normal, immunofixation (IF) detects monoclonal mu IgH in polymers of ...
more infohttp://documents.irevues.inist.fr/handle/2042/68123/discover?filtertype_0=author&filter_0=Anderson%2C+Kenneth+C&filter_relational_operator_0=equals&filtertype=subject&filter_relational_operator=equals&filter=Blood+Protein+Electrophoresis

WHAT CAUSES HIGHT PROTEIN LEVELS IN ONES BLOOD AND BONES? DADS MEDICAL CONDITION--HE WAS VERY SICK WITH BROCHITIS ANDWHAT CAUSES HIGHT PROTEIN LEVELS IN ONE'S BLOOD AND BONES? DAD'S MEDICAL CONDITION--HE WAS VERY SICK WITH BROCHITIS AND

WHAT CAUSES HIGHT PROTEIN LEVELS IN ONES BLOOD AND BONES? DADS MEDICAL CONDITION--HE WAS VERY SICK WITH BROCHITIS AND - ... Serum protein electrophoresis (blood test). Serum albumin/globulin ratio (another blood test) ... WHAT CAUSES HIGHT PROTEIN LEVELS IN ONES BLOOD AND BONES?. Doctors Assistant: How long have you had blood? Have you used any ... Actually, a high protein level in the blood (which is significantly elevated as you have indicated) is usually an indication of ...
more infohttps://www.justanswer.com/medical/bb6c6-causes-hight-protein-levels-one-s-blood-bones.html

Wanted Lectin A of Lens culinarisWanted Lectin A of Lens culinaris

Hello Help, help ! I need Lens culinaris Lectin A for affinity electrophoresis of a blood protein. I found only A+B Lectin ...
more infohttp://www.bio.net/bionet/mm/immuno/1995-March/003269.html

Find Publications
             - Oregon Health & Science UniversityFind Publications - Oregon Health & Science University

Cline, M. J., Hanifin, J. & Lehrer, R. I., Dec 1968, In : Blood. 32, 6, p. 922-934 13 p.. Research output: Contribution to ... Protein migration through the nuclear membrane.. Kabat, D., May 25 1968, In : Journal of Biological Chemistry. 243, 10, p. 2597 ... Protein synthesis: Differential stimulation of cell-specific proteins in epithelial cells of chick oviduct. Kohler, P., Grimley ... Blood circulation aided with the use of an intrathoracic balloon. Experimental results in left ventricular insufficiency. ...
more infohttps://ohsu.pure.elsevier.com/en/publications/?showAdvanced=false&allConcepts=true&inferConcepts=true&originalSearch=&improvedLayoutOrganisationUuid=&format=&page=1692

Nicks Myeloma Blog: May 2013Nick's Myeloma Blog: May 2013

Serum blood protein electrophoresis. AND. *Bone marrow aspiration or biopsy. Additionally, in order to qualify for SSD benefits ... although based on the evidence its probably not a good idea to pound this stuff if you have blood cancer, MM included. But a ...
more infohttp://nvdmyeloma.blogspot.com/2013/05/

Effect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in miceEffect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice

At the end of the experiment, blood was taken for white cell count and blood protein electrophoresis was used. The data ... This study investigated the effect of the plants role in the immune system and blood protein. Experimental: In this study male ... Results and discussion: Studies suggest that the extracts of Nigella sativa in the groups are able to increase white blood cell ... count, protein and albumin, alpha 1 and 2 and the A/G. Industrial/Practical recommendation: According to the survey results ...
more infohttp://jhd.iaushk.ac.ir/article_633217.html

Genetic Diversity of 10 Indigenous Pig Breeds in China by Using Microsatellite Markers | Korea ScienceGenetic Diversity of 10 Indigenous Pig Breeds in China by Using Microsatellite Markers | Korea Science

Genetic relationship among several native pig breeds in Southwest China: An approach from blood protein electrophoresis. ... Studies in protein electrophoresis and mtDNA polymorphism of Zhejiang Jinhua pig breeds. Proceedings of $10^{th}$. National ... Comparison of protein markers and microsatellites in differentiation of cattle populations. Anim. Genet. 27:415-419. ... Genetic variation and genetic relationship of seventeen Chinese indigenous pig breeds using ten serum protein loci. Asian-Aust ...
more infohttp://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1DMBP_2004_v17n9_1219

Jornal Brasileiro de Patologia e Medicina Laboratorial - SumárioJornal Brasileiro de Patologia e Medicina Laboratorial - Sumário

Keywords: sickle-cell anemia; hemoglobinopathies; haplotypes; blood protein electrophoresis. PATOLOGIA. Lesões intraepiteliais ... MATERIALS AND METHOD: 133 CNS isolates from whole blood samples from September 2015 to May 2016 were analyzed.. RESULTS: All ... As mutações de IDH1 precedem mutações de tumor protein p53 (TP53) em cerca de 63% dos casos de astrocitomas difusos e resultam ... IDH1 mutations precede tumor protein p53 (TP53) mutations in around 63% of cases of diffuse astrocytomas, and result in loss in ...
more infohttp://jbpml.org.br/sumario

Kosto e analizave-healthgate4all.grKosto e analizave-healthgate4all.gr

Agarose gel HB electrophoresis. 9,51 €. 272. Blood protein electrophoresis. 10,68 €. ...
more infohttp://uoa.campaign.com.gr/pages/uoakiosk/al/check_cost.php

Facilities | Aswini Diagnostic CalicutFacilities | Aswini Diagnostic Calicut

Blood protein electrophoresis analyser.. Quick Contact. Tel : 0495 2703250. E mail : [email protected] ...
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Online Information | Aswini Diagnostic CalicutOnline Information | Aswini Diagnostic Calicut

Blood protein electrophoresis analyser.. Quick Contact. Tel : 0495 2703250. E mail : [email protected] ...
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M Protein (Myeloma Protein): Spike, Monoclonal, in Blood, MoreM Protein (Myeloma Protein): Spike, Monoclonal, in Blood, More

If you have a lot of it in your blood, it can signal certain conditions and risks, though it more frequently has no ill health ... M protein is an abnormal protein produced by plasma cells. ... Urine protein tests. Urine protein electrophoresis (UPEP) and ... To find these identical M proteins, your doctor might run a blood test called serum protein electrophoresis (SPEP). It involves ... Most people are diagnosed with MGUS during blood tests for other conditions that affect the bloods protein levels, such as a ...
more infohttps://www.healthline.com/health/m-protein

Immunology and archaeology : blood residue analysis of three sites by Shirley Jo Barr Williams"Immunology and archaeology : blood residue analysis of three sites" by Shirley Jo Barr Williams

... an immunological method for analyzing blood residues on archaeological artifacts, is tested. Artifacts from three sites were ... Cross-over electrophoresis, an immunological method for analyzing blood residues on archaeological artifacts, is tested. ... Williams, Shirley Jo Barr, "Immunology and archaeology : blood residue analysis of three sites" (1990). Dissertations and ... Blood protein electrophoresis, Crossed immunoelectrophoresis, Archaeology -- Methodology. DOI. 10.15760/etd.6008. Abstract. ...
more infohttps://pdxscholar.library.pdx.edu/open_access_etds/4124/

How Feline Infectious Peritonitis (FIP) DevelopsHow Feline Infectious Peritonitis (FIP) Develops

Blood samples from cats with very high blood protein levels can be submitted for serum protein electrophoresis testing. ... Routine blood tests, including a complete blood count and serum biochemistry profile, can show elevated liver enzymes, anemia, ... and abnormal blood protein levels, which are typical of kitties with FIP. ... Cerebral spinal fluid samples can also be analyzed for protein content, which is typically elevated in FIP cats. But the only ...
more infohttps://healthypets.mercola.com/sites/healthypets/archive/2013/04/22/feline-infectious-peritonitis.aspx
  • Effect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice', Journal of Herbal Drugs (An International Journal on Medicinal Herbs) , 2(1), pp. 53-58. (ac.ir)
  • Modaresi, M. Effect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice. (ac.ir)
  • This study investigated the effect of the plant's role in the immune system and blood protein. (ac.ir)
  • EPR-HV3HSA elicited less blood loss than constitutively active HV3HSA in murine liver laceration or tail transection but extended bleeding time to the same extent. (springer.com)
  • Globulins play an important role in liver function, blood clotting, and fighting infection. (medlineplus.gov)
  • Therefore, plasma samples from 156 healthy blood donors (79 females and 77 males) have been analyzed with the Capillarys instrument and the new high resolution buffer, which yields higher resolution than the b1-b2+ buffer. (diva-portal.org)
  • The Capillarys instrument is a reliable system for plasma protein analysis, combining advantages of full automation with high analytical performances and throughput. (diva-portal.org)
  • If the total protein count is truly ten times the normal range then he should be investigated with the above tests as soon as possible. (justanswer.com)
  • They can be found in all types of body tissues, including the blood. (healthline.com)
  • This type of antibody is also found in saliva, tears, and blood. (nkch.org)
  • The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. (healthtap.com)
  • 133 CNS isolates from whole blood samples from September 2015 to May 2016 were analyzed. (jbpml.org.br)
  • If you have diabetes, then that means you have too much glucose in your blood, which can lead to serious health issues. (personalabs.com)
  • Lastly, very high protein count can also be due to chronic inflammation in the body due to viral infections or even atypical bacterial infections which is why blood cultures etc should also be done here. (justanswer.com)
  • The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. (wikipedia.org)
  • 1995. Genetic relationship among several native pig breeds in Southwest China: An approach from blood protein electrophoresis. (koreascience.or.kr)
  • There is very little chance of a problem from having a blood sample taken from a vein. (nkch.org)
  • In rare cases, the vein may become swollen after the blood sample is taken. (nkch.org)
  • 1996. Comparison of protein markers and microsatellites in differentiation of cattle populations. (koreascience.or.kr)
  • 1997. Genetic diversity of Asian water buffalo (Bubalus bubalis): microsatellite variation and a comparison with protein-coding loci. (koreascience.or.kr)
  • Other costs of transporting and shipping frozen plasma and final finished products further complicate delivery of heat-labile protein products ( 5 ). (bioprocessintl.com)
  • This protein may have a proliferative effect and play a role in cancer development or progression. (wikipedia.org)
  • The more M proteins in your blood and the longer you've had MGUS, the higher your risk of developing one or more related conditions. (healthline.com)
  • Diabetes mellitus, commonly known as diabetes, is a group of diseases that affect how your body processes blood sugar. (personalabs.com)