The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Solutions used to store organs and minimize tissue damage, particularly while awaiting implantation.
The process of protecting various samples of biological material.
A method of providing future reproductive opportunities before a medical treatment with known risk of loss of fertility. Typically reproductive organs or tissues (e.g., sperm, egg, embryos and ovarian or testicular tissues) are cryopreserved for future use before the medical treatment (e.g., chemotherapy, radiation) begins.
A trisaccharide occurring in Australian manna (from Eucalyptus spp, Myrtaceae) and in cottonseed meal.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
The process by which semen is kept viable outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
Procedures or techniques used to keep food from spoiling.
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
The chilling of a tissue or organ during decreased BLOOD perfusion or in the absence of blood supply. Cold ischemia time during ORGAN TRANSPLANTATION begins when the organ is cooled with a cold perfusion solution after ORGAN PROCUREMENT surgery, and ends after the tissue reaches physiological temperature during implantation procedures.
Liquids transforming into solids by the removal of heat.
Techniques, procedures, and therapies carried out on diseased organs in such a way to avoid complete removal of the organ and preserve the remaining organ function.
Total or partial excision of the larynx.
Elements of limited time intervals, contributing to particular results or situations.
Remains, impressions, or traces of animals or plants of past geological times which have been preserved in the earth's crust.
An absence of warmth or heat or a temperature notably below an accustomed norm.
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Bodies preserved either by the ancient Egyptian technique or due to chance under favorable climatic conditions.
Agents employed in the preparation of histologic or pathologic specimens for the purpose of maintaining the existing form and structure of all of the constituent elements. Great numbers of different agents are used; some are also decalcifying and hardening agents. They must quickly kill and coagulate living tissue.

Storage of cord blood attracts private-sector interest. (1/586)

Storage of cord blood from their babies can cost parents several hundred dollars, and some private companies are already offering the service. Janis Hass reports that some Canadian specialists question the value of the banks.  (+info)

Freezer anthropology: new uses for old blood. (2/586)

Archived blood fractions (plasma, settled red cells, white cells) have proved to be a rich and valuable source of DNA for human genetic studies. Large numbers of such samples were collected between 1960 and the present for protein and blood group studies, many of which are languishing in freezers or have already been discarded. More are discarded each year because the usefulness of these samples is not widely understood. Data from DNA derived from 10-35-year-old blood samples have been used to address the peopling of the New World and of the Pacific. Mitochondrial DNA haplotypes from studies using this source DNA support a single wave of migration into the New World (or a single source population for the New World), and that Mongolia was the likely source of the founding population. Data from Melanesia have shown that Polynesians are recent immigrants into the Pacific and did not arise from Melanesia.  (+info)

Correlation of cytokine elaboration with mononuclear cell adhesion to platelet storage bag plastic polymers: a pilot study. (3/586)

The basis for many febrile nonhemolytic transfusion reactions associated with platelet transfusion therapy is cytokine elaboration and accumulation in the storage bag, which correlate with the leukocyte content and the length of platelet storage. We propose that a possible additional variable in the elaboration and accumulation of cytokines is the differential adhesion of mononuclear cells to the plastic substrate of the platelet storage bag. We hypothesize that mononuclear cell adhesion-induced cytokine release is greater in random-donor platelet bags composed of the polyolefin polymer compared to the single-donor apheresis platelet bags composed of the polyvinyl chloride polymer with the tri-(2-ethylhexyl) trimellitate (TEHTM) plasticizer. For four blood donors, we demonstrate preferential mononuclear cell adhesion, in vitro, to discs of polyolefin polymer versus discs of polyvinyl chloride polymer with the TEHTM plasticizer. Scanning electron microscopy corroborates this. In addition, proinflammatory cytokine (interleukin 1beta [IL-1beta] and tumor necrosis factor alpha [TNF-alpha]) levels are greater in culture wells containing discs of polyolefin polymer than in those containing discs of polyvinyl chloride polymer with the TEHTM plasticizer, and even more so in storage bags containing polyolefin polymer versus polyvinyl chloride polymer with the TEHTM plasticizer (IL-1beta, TNF-alpha, IL-6, and IL-8). This study suggests, for the first time, that differential plastic substrate mononuclear cell adhesion may contribute to cytokine release during platelet storage. This may represent an additional variable in the pathophysiology of febrile nonhemolytic transfusion reactions in patients receiving stored platelet units.  (+info)

Heat treatment of normal human sera reveals antibodies to bactericidal permeability-inducing protein (BPI). (4/586)

Heat treatment of normal sera to 56 degrees C for 30 min, a common procedure for the inactivation of viruses, e.g. HIV, reveals the presence of antibodies to neutrophil cytoplasm antigens (ANCA), as detected by indirect immunofluorescence on ethanol-fixed human neutrophils and by antigen-specific ELISA for BPI. Reactivity was not seen to the other common vasculitis-associated antigens proteinase 3 (PR3) or myeloperoxidase (MPO). The effect of temperature was maximal at 56 degrees C, with substantial antibody demonstrable after only 5 min at this temperature. In experiments using polyethylene glycol (PEG)6000 to remove immune complexes, the effect of heating could be abrogated by preincubation with 8% PEG, which suggested that these anti BPI antibodies might be complexed in sera. After passage of normal plasma over a protein G column, the acid-eluted fraction contained elevated levels of antibodies to BPI but not to other vasculitis-associated antigens such as PR3 or MPO, nor to glomerular basement membrane (GBM), the Goodpasture antigen which is recognized by the pathogenically important human antibodies shown to mediate nephritis in transfer experiments. Moreover the levels of anti-BPI in the IgG fraction could be augmented by preincubation with glycine pH 2.5 for 30 min. This anti-BPI activity could be inhibited by addition of the unbound material from the protein G column and this inhibitory material was not heat-labile at 56 degrees C. The molecular specificity of this autoreactivity was confirmed using recombinant BPI in coincubation experiments and the epitope localized to the C or N terminal moieties by the use of recombinant fusion proteins.  (+info)

Monitoring oral anticoagulant treatment from plasma stored for up to 48 hours and frozen plasma. (5/586)

BACKGROUND AND OBJECTIVE: The number of patients being referred for lifelong anticoagulant treatment has increased markedly in the last years. The prothrombin time test is sometimes difficult to perform the same day as sample collection. The aim of this study is to determine International Normalized Ratio (INR) and vitamin-K dependent factor levels of frozen plasma and plasma stored for up 48 hours. DESIGN AND METHODS: The INR of 84 patients receiving acenocoumarol were determined fresh (0 hours), on samples stored between 2 degrees C and 8 degrees C for 24 hours and 48 hours, and on frozen samples (-40 degrees C) using 4 different thromboplastin reagents (Thromboplastin IS; Thromborel; Simplastin; and Thromboplastin D+G). In addition, factors II, VII, IX, X were determined in 34 of these patients in all these situations. We used the interclass correlation coefficient to compare the results obtained at 0 hours and the results obtained in the subsequent measurements. Both measurement and proportional errors were also estimated by linear regression analysis. RESULTS: The correlation coefficient of the INR between fresh and frozen plasma was 0.98, 0.98, 0.92 and 0.97 for IS, Thromborel, Simplastin and D+G respectively. The correlation between 0 and 24 hours was 0. 98, 0.91, 0.95 and 0.85 for IS, Thromborel, Simplastin and D+G respectively. By 48 hours although IS still had r=0.94, Thromborel, Simplastin, and D+G had r=0.55, r=0.50 and r=0.81, respectively. By 24 hours in stored plasma and in frozen plasma the activity of vitamin-K dependent factors was slightly reduced (r=0.97 at 24h/r=0. 94 with frozen plasma for factor II, r=0.92/0.96 for factor VII, r=0. 83/0.98 for factor IX, and r=0.98/0.95 for factor X). By 48 hours however, significant reductions were noted in the activity of these factors (r=0.94 for factor II, r=0.88 for factor VII, r=0.70 for factor IX, and r=0.98 for factor X). INTERPRETATION AND CONCLUSIONS: The INR can be reliable determined in frozen plasma and in plasma stored at 2-8 degrees C for up to 24 hours.  (+info)

Assessment of the stability of N-terminal pro-brain natriuretic peptide in vitro: implications for assessment of left ventricular dysfunction. (6/586)

Plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are raised in patients with left ventricular dysfunction. Measurement of this peptide has a potential diagnostic role in the identification and assessment of patients with heart failure. The stability of this peptide over time periods and conditions pertaining to routine clinical practice has not been reported previously. Blood samples were obtained from 15 subjects. One aliquot was processed immediately, and the remaining portions of the blood samples were stored for 24 h or 48 h at room temperature or on ice prior to processing. Plasma concentrations of NT-proBNP were measured with a novel immunoluminometric assay developed within our laboratory. Mean plasma concentrations of NT-proBNP were not significantly different whether blood samples were centrifuged immediately and stored at -70 degrees C or kept at room temperature or on ice for 24 h or 48 h. The mean percentage differences from baseline (reference standard) were +5.2% (95% confidence interval +18.2 to -7.8%) and +0.8% (+15.2 to -13.7%) after storage for 24 h at room temperature or on ice respectively, and +8.9% (+24.2 to -6. 5%) and +3.2% (+15.1 to -0.9%) for storage for 48 h at room temperature or on ice respectively. Pearson correlation coefficients for baseline NT-proBNP concentrations compared with levels at 48 h at room temperature or on ice were r=0.89 and r=0.83 respectively (both P<0.0001). Thus NT-proBNP extracted from plasma samples treated with EDTA and aprotinin is stable under conditions relevant to clinical practice.  (+info)

Preanalytical variables affecting the quantification of fatty acid ethyl esters in plasma and serum samples. (7/586)

BACKGROUND: Fatty acid ethyl esters (FAEEs) are cytotoxic nonoxidative ethanol metabolites produced by esterification of fatty acids and ethanol. FAEEs are detectable in blood up to 24 h after ethanol consumption. The objective of this study was to assess the impact of gender, serum or plasma triglyceride concentration, time and temperature of specimen storage, type of alcoholic beverage ingested, and the rate of ethanol consumption on FAEE concentrations in plasma or serum. METHODS: For some studies, subject were recruited volunteers; in others, residual blood samples after ethanol quantification were used. FAEEs were isolated by solid-phase extraction and quantified by gas chromatography-mass spectrometry. RESULTS: For weight-adjusted amounts of ethanol intake, FAEE concentrations were twofold greater for men than women (P /=24 h. The type of alcoholic beverage and rate of consumption did not affect FAEE concentrations. CONCLUSION: These studies advance plasma and serum FAEE measurements closer to implementation as a clinical test for ethanol intake.  (+info)

Increased serum transferrin saturation is associated with lower serum transferrin receptor concentration. (8/586)

BACKGROUND: Serum transferrin receptor (sTfR) concentrations are increased in iron deficiency. We wished to examine whether they are decreased in the presence of potential iron-loading conditions, as reflected by increased transferrin saturation (TS) on a single occasion. METHODS: We compared sTfR concentrations between 570 controls with normal iron status and 189 cases with increased serum TS on a single occasion; these latter individuals may be potential cases of iron overload. Cases and controls were selected from adults who had been examined in the third National Health and Nutrition Examination Survey (1988-1994) and for whom excess sera were available to perform sTfR measurements after the survey's completion. Increased TS was defined as >60% for men and >55% for women; normal iron status was defined as having no evidence of iron deficiency, iron overload, or inflammation indicated by serum ferritin, TS, erythrocyte protoporphyrin, and C-reactive protein. RESULTS: Mean sTfR and mean log sTfR:ferritin were approximately 10% and 24% lower, respectively, in cases than in controls (P <0.002). Cases were significantly more likely to have an sTfR value <2.9 mg/L, the lower limit of the reference interval, than were controls (odds ratio = 1.8; 95% confidence interval, 1.04-2.37). CONCLUSION: Our results support previous studies that suggested that sTfR may be useful for assessing high iron status in populations.  (+info)

Blood preservation refers to the process of keeping blood viable and functional outside of the body for transfusion purposes. This is typically achieved through the addition of various chemical additives, such as anticoagulants and nutrients, to a storage solution in which the blood is contained. The preserved blood is then refrigerated or frozen until it is needed for transfusion.

The goal of blood preservation is to maintain the structural integrity and functional capacity of the red blood cells, white blood cells, and platelets, as well as the coagulation factors, in order to ensure that the transfused blood is safe and effective. Different storage conditions and additives are used for the preservation of different components of blood, depending on their specific requirements.

It's important to note that while blood preservation extends the shelf life of donated blood, it does not last indefinitely. The length of time that blood can be stored depends on several factors, including the type of blood component and the storage conditions. Regular testing is performed to ensure that the preserved blood remains safe and effective for transfusion.

Organ preservation is a medical technique used to maintain the viability and functionality of an organ outside the body for a certain period, typically for transplantation purposes. This process involves cooling the organ to slow down its metabolic activity and prevent tissue damage, while using specialized solutions that help preserve the organ's structure and function. Commonly preserved organs include hearts, livers, kidneys, lungs, and pancreases. The goal of organ preservation is to ensure that the transplanted organ remains in optimal condition until it can be successfully implanted into a recipient.

Organ preservation solutions are specialized fluids used to maintain the viability and functionality of organs ex vivo (outside the body) during the process of transplantation. These solutions are designed to provide optimal conditions for the organ by preventing tissue damage, reducing metabolic activity, and minimizing ischemic injuries that may occur during the time between organ removal from the donor and implantation into the recipient.

The composition of organ preservation solutions typically includes various ingredients such as:

1. Cryoprotectants: These help prevent ice crystal formation and damage to cell membranes during freezing and thawing processes, especially for organs like the heart and lungs that require deep hypothermia for preservation.
2. Buffers: They maintain physiological pH levels and counteract acidosis caused by anaerobic metabolism in the absence of oxygen supply.
3. Colloids: These substances, such as hydroxyethyl starch or dextran, help preserve oncotic pressure and prevent cellular edema.
4. Electrolytes: Balanced concentrations of ions like sodium, potassium, calcium, magnesium, chloride, and bicarbonate are essential for maintaining physiological osmolarity and membrane potentials.
5. Energy substrates: Glucose, lactate, or other energy-rich compounds can serve as fuel sources to support the metabolic needs of the organ during preservation.
6. Antioxidants: These agents protect against oxidative stress and lipid peroxidation induced by ischemia-reperfusion injuries.
7. Anti-inflammatory agents and immunosuppressants: Some solutions may contain substances that mitigate the inflammatory response and reduce immune activation in the transplanted organ.

Examples of commonly used organ preservation solutions include University of Wisconsin (UW) solution, Histidine-Tryptophan-Ketoglutarate (HTK) solution, Custodiol HTK solution, and Euro-Collins solution. The choice of preservation solution depends on the specific organ being transplanted and the duration of preservation required.

Biological preservation is the process of preventing decomposition or decay of biological materials, such as tissues, cells, organs, or organisms, in order to maintain their structural and functional integrity for further studies, research, education, or conservation purposes. This can be achieved through various methods, including fixation, freezing, drying, or the use of chemical preservatives. The goal is to maintain the samples in a stable state so that they can be examined, analyzed, or used in experiments at a later time.

Fertility preservation is a medical procedure or treatment that is aimed at protecting and preserving the reproductive function and potential of an individual, typically before undergoing medical treatments that can potentially compromise their fertility. This may involve the cryopreservation (freezing) and storage of gametes (sperm or eggs), embryos, or reproductive tissues, such as ovarian or testicular tissue, for future use.

Fertility preservation is often recommended for individuals who are facing medical treatments that can have a negative impact on their fertility, such as chemotherapy, radiation therapy, or surgical removal of reproductive organs. It may also be considered for individuals with conditions that can affect their fertility, such as certain genetic disorders or autoimmune diseases.

The goal of fertility preservation is to allow individuals to have biological children in the future, even if their fertility is compromised by medical treatments or conditions. The success of fertility preservation depends on several factors, including the age and health of the individual at the time of preservation, the type and duration of the medical treatment, and the quality of the preserved gametes or tissues.

Raffinose is a complex carbohydrate, specifically an oligosaccharide, that is composed of three sugars: galactose, fructose, and glucose. It is a non-reducing sugar, which means it does not undergo oxidation reactions like reducing sugars do.

Raffinose is found in various plants, including beans, cabbage, brussels sprouts, broccoli, and whole grains. It is a member of the class of carbohydrates known as alpha-galactosides.

In humans, raffinose cannot be digested because we lack the enzyme alpha-galactosidase, which is necessary to break down the bond between galactose and glucose in raffinose. As a result, it passes through the small intestine intact and enters the large intestine, where it is fermented by gut bacteria. This fermentation process can lead to the production of gases such as methane and hydrogen, which can cause digestive discomfort, bloating, and flatulence in some individuals.

It's worth noting that raffinose has been studied for its potential prebiotic properties, as it can promote the growth of beneficial gut bacteria. However, excessive consumption may lead to digestive issues in sensitive individuals.

Cryopreservation is a medical procedure that involves the preservation of cells, tissues, or organs by cooling them to very low temperatures, typically below -150°C. This is usually achieved using liquid nitrogen. The low temperature slows down or stops biological activity, including chemical reactions and cellular metabolism, which helps to prevent damage and decay.

The cells, tissues, or organs that are being cryopreserved must be treated with a cryoprotectant solution before cooling to prevent the formation of ice crystals, which can cause significant damage. Once cooled, the samples are stored in specialized containers or tanks until they are needed for use.

Cryopreservation is commonly used in assisted reproductive technologies, such as the preservation of sperm, eggs, and embryos for fertility treatments. It is also used in research, including the storage of cell lines and stem cells, and in clinical settings, such as the preservation of skin grafts and corneas for transplantation.

Semen preservation is the process of collecting, liquefying, testing, and storing semen samples for future use in assisted reproductive technologies (ART) such as artificial insemination (AI), in vitro fertilization (IVF), or intracytoplasmic sperm injection (ICSI). The semen sample is usually collected through masturbation, and then it is mixed with a cryoprotectant solution to prevent damage during the freezing and thawing process. After that, the sample is divided into straws or vials and frozen in liquid nitrogen tanks at temperatures below -196°C. Properly preserved semen can be stored for many years without significant loss of quality or fertility potential. Semen preservation is often recommended for men who are about to undergo medical treatments that may affect their sperm production or fertility, such as chemotherapy or radiation therapy, or for those who wish to postpone fatherhood for personal or medical reasons.

Allopurinol is a medication used to treat chronic gout and certain types of kidney stones. It works by reducing the production of uric acid in the body, which is the substance that can cause these conditions when it builds up in high levels. Allopurinol is a xanthine oxidase inhibitor, meaning it blocks an enzyme called xanthine oxidase from converting purines into uric acid. By doing this, allopurinol helps to lower the levels of uric acid in the body and prevent the formation of new kidney stones or gout attacks.

It is important to note that allopurinol can have side effects, including rash, stomach upset, and liver or kidney problems. It may also interact with other medications, so it is essential to inform your healthcare provider of any other drugs you are taking before starting allopurinol. Your healthcare provider will determine the appropriate dosage and monitoring schedule based on your individual needs and medical history.

Food preservation, in the context of medical and nutritional sciences, refers to the process of treating, handling, and storing food items to reduce the risk of foodborne illness and to extend their shelf life. The goal is to prevent the growth of pathogenic microorganisms such as bacteria, yeasts, and mold, as well as to slow down the oxidation process that can lead to spoilage.

Common methods of food preservation include:

1. Refrigeration and freezing: These techniques slow down the growth of microorganisms and enzyme activity that cause food to spoil.
2. Canning: This involves sealing food in airtight containers, then heating them to destroy microorganisms and inactivate enzymes.
3. Dehydration: Removing water from food inhibits the growth of bacteria, yeasts, and molds.
4. Acidification: Adding acidic ingredients like lemon juice or vinegar can lower the pH of food, making it less hospitable to microorganisms.
5. Fermentation: This process involves converting sugars into alcohol or acids using bacteria or yeasts, which can preserve food and also enhance its flavor.
6. Irradiation: Exposing food to small doses of radiation can kill bacteria, parasites, and insects, extending the shelf life of certain foods.
7. Pasteurization: Heating food to a specific temperature for a set period of time can destroy harmful bacteria while preserving the nutritional value and taste.

Proper food preservation is crucial in preventing foodborne illnesses and ensuring the safety and quality of the food supply.

Freeze-drying, also known as lyophilization, is a method of preservation that involves the removal of water from a frozen product by sublimation, which is the direct transition of a solid to a gas. This process allows for the preservation of the original shape and structure of the material while significantly extending its shelf life. In medical contexts, freeze-drying can be used for various purposes, including the long-term storage of pharmaceuticals, vaccines, and diagnostic samples. The process helps maintain the efficacy and integrity of these materials until they are ready to be reconstituted with water and used.

Cold ischemia is a medical term that refers to the loss of blood flow and subsequent lack of oxygen delivery to an organ or tissue, which is then cooled and stored in a solution at temperatures between 0-4°C (32-39°F) for the purpose of transplantation. The term "cold" indicates the temperature range, while "ischemia" refers to the lack of blood flow and oxygen delivery to the tissue.

During cold ischemia, the metabolic activity of the organ or tissue slows down significantly, which helps to reduce the rate of cellular damage that would otherwise occur due to the absence of oxygen and nutrients. However, even with cold storage, there is still some degree of injury to the organ or tissue, and this can affect its function after transplantation.

The duration of cold ischemia time is an important factor in determining the success of a transplant procedure. Prolonged cold ischemia times are associated with increased risk of poor organ function and rejection, as well as decreased graft survival rates. Therefore, it is essential to minimize the cold ischemia time as much as possible during organ transplantation to ensure optimal outcomes for the recipient.

"Freezing" is a term used in the medical field to describe a phenomenon that can occur in certain neurological conditions, most notably in Parkinson's disease. It refers to a sudden and temporary inability to move or initiate movement, often triggered by environmental factors such as narrow spaces, turning, or approaching a destination. This can increase the risk of falls and make daily activities challenging for affected individuals.

Freezing is also known as "freezing of gait" (FOG) when it specifically affects a person's ability to walk. During FOG episodes, the person may feel like their feet are glued to the ground, making it difficult to take steps forward. This can be very distressing and debilitating for those affected.

It is important to note that "freezing" has different meanings in different medical contexts, such as in the field of orthopedics, where it may refer to a loss of joint motion due to stiffness or inflammation. Always consult with a healthcare professional for accurate information tailored to your specific situation.

Organ sparing treatments refer to medical interventions that are designed to preserve the structure and function of an organ, while still effectively treating the underlying disease or condition. These treatments can include surgical techniques, radiation therapy, or medications that aim to target specific cells or processes involved in the disease, while minimizing damage to healthy tissues.

Organ sparing treatments may be used in a variety of medical contexts, such as cancer treatment, where the goal is to eliminate malignant cells while preserving as much normal tissue as possible. For example, radiation therapy may be delivered with precise techniques that limit exposure to surrounding organs, or medications may be used to target specific receptors on cancer cells, reducing the need for more extensive surgical interventions.

Similarly, in the context of kidney disease, organ sparing treatments may include medications that help control blood pressure and reduce proteinuria (protein in the urine), which can help slow the progression of kidney damage and potentially delay or prevent the need for dialysis or transplantation.

Overall, organ sparing treatments represent an important area of medical research and practice, as they offer the potential to improve patient outcomes, reduce treatment-related morbidity, and maintain quality of life.

A laryngectomy is a surgical procedure that involves the removal of the larynx, also known as the voice box. This is typically performed in cases of advanced laryngeal cancer or other severe diseases of the larynx. After the surgery, the patient will have a permanent stoma (opening) in the neck to allow for breathing. The ability to speak after a total laryngectomy can be restored through various methods such as esophageal speech, tracheoesophageal puncture with a voice prosthesis, or electronic devices.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

In medical terms, "fossils" do not have a specific or direct relevance to the field. However, in a broader scientific context, fossils are the remains or impressions of prehistoric organisms preserved in petrified form or as a mold or cast in rock. They offer valuable evidence about the Earth's history and the life forms that existed on it millions of years ago.

Paleopathology is a subfield of paleontology that deals with the study of diseases in fossils, which can provide insights into the evolution of diseases and human health over time.

"Cold temperature" is a relative term and its definition can vary depending on the context. In general, it refers to temperatures that are lower than those normally experienced or preferred by humans and other warm-blooded animals. In a medical context, cold temperature is often defined as an environmental temperature that is below 16°C (60.8°F).

Exposure to cold temperatures can have various physiological effects on the human body, such as vasoconstriction of blood vessels near the skin surface, increased heart rate and metabolic rate, and shivering, which helps to generate heat and maintain body temperature. Prolonged exposure to extreme cold temperatures can lead to hypothermia, a potentially life-threatening condition characterized by a drop in core body temperature below 35°C (95°F).

It's worth noting that some people may have different sensitivities to cold temperatures due to factors such as age, health status, and certain medical conditions. For example, older adults, young children, and individuals with circulatory or neurological disorders may be more susceptible to the effects of cold temperatures.

Mannitol is a type of sugar alcohol (a sugar substitute) used primarily as a diuretic to reduce brain swelling caused by traumatic brain injury or other causes that induce increased pressure in the brain. It works by drawing water out of the body through the urine. It's also used before surgeries in the heart, lungs, and kidneys to prevent fluid buildup.

In addition, mannitol is used in medical laboratories as a medium for growing bacteria and other microorganisms, and in some types of chemical research. In the clinic, it is also used as an osmotic agent in eye drops to reduce the pressure inside the eye in conditions such as glaucoma.

It's important to note that mannitol should be used with caution in patients with heart or kidney disease, as well as those who are dehydrated, because it can lead to electrolyte imbalances and other complications.

Reperfusion injury is a complex pathophysiological process that occurs when blood flow is restored to previously ischemic tissues, leading to further tissue damage. This phenomenon can occur in various clinical settings such as myocardial infarction (heart attack), stroke, or peripheral artery disease after an intervention aimed at restoring perfusion.

The restoration of blood flow leads to the generation of reactive oxygen species (ROS) and inflammatory mediators, which can cause oxidative stress, cellular damage, and activation of the immune system. This results in a cascade of events that may lead to microvascular dysfunction, capillary leakage, and tissue edema, further exacerbating the injury.

Reperfusion injury is an important consideration in the management of ischemic events, as interventions aimed at restoring blood flow must be carefully balanced with potential harm from reperfusion injury. Strategies to mitigate reperfusion injury include ischemic preconditioning (exposing the tissue to short periods of ischemia before a prolonged ischemic event), ischemic postconditioning (applying brief periods of ischemia and reperfusion after restoring blood flow), remote ischemic preconditioning (ischemia applied to a distant organ or tissue to protect the target organ), and pharmacological interventions that scavenge ROS, reduce inflammation, or improve microvascular function.

In the field of medicine and particularly in forensic pathology, mummies are human or animal bodies that have been preserved naturally or intentionally after death, through processes such as desiccation (drying), freezing, or exposure to chemicals like salt or smoke. The study of mummies, known as mummy science or mummy studies, can provide valuable insights into various aspects including the biological characteristics, health conditions, dietary habits, and cultural practices of past civilizations.

Fixatives are substances used in histology and pathology to preserve tissue specimens for microscopic examination. They work by stabilizing the structural components of cells and tissues, preventing decomposition and autolysis. This helps to maintain the original structure and composition of the specimen as closely as possible, allowing for accurate diagnosis and research. Commonly used fixatives include formalin, glutaraldehyde, methanol, and ethanol. The choice of fixative depends on the specific type of tissue being preserved and the intended use of the specimen.

Preservation of Blood Platelets. US Patent Number 5,876,676, issued March 2, 1999. 7. Stossel, TP, Hartwig, JH, Hoffmeister, KM ... Molecular basis of white blood cell motility. In: The Molecular Basis Of Blood Disorders, G Stamatoyannopoulos, AW Nienhuis, PW ... Blood. 2015;125:1116-25 155. Kumar, AA, Chunda-Liyoka, C, Hennek, JW, Mantina, H, Ryan Lee, SY, Patton, MR, Sambo, P, Sinyangwe ... Blood. 1980; 56:442-447. 55. Crowley CA, Curnutte JI, Rosin RE, Andre'-Swartz J, Gallin JI, Klempner M, Snyderman R, Southwick ...
The Methodist program implemented the first donor blood cryo-preservation allowing the rapid cross matching of pairs in a swap ... "National Kidney Registry Initiates Donor Blood Cryo-Preservation". National Kidney Registry. 2014-12-02. "United Network for ... A favorable blood type compatible pair (i.e. O donor with non-O recipient) will facilitate at least one and as many as six ... Although the merits of using cryo-preserved donor blood for cross matching were clear, it proved difficult for multi-center KPD ...
"National Kidney Registry Initiates Donor Blood Cryo-Preservation" (Press release). National Kidney Registry. December 2, 2014. ... Donor blood cryopreservation also reduces the number of times a donor needs to have blood drawn for cross matching, making ... Cryopreserved donor blood - Human blood can be cryopreserved and stored indefinitely in liquid nitrogen freezers at a ... In 2015, the NKR created a national lab service, so cryopreserved donor blood could be stored for donors across NKR's 70+ ...
Janko, Marek; Stark, Robert W.; Zink, Albert (7 October 2012). "Preservation of 5300 year old red blood cells in the Iceman". ... These are the oldest complete human blood cells ever identified. In most bodies this old, the blood cells are either shrunken ... DNA analyses taken in 2003 are claimed to have revealed traces of blood from at least four other people on his gear: one from ... One body was sent to a museum in the hope that research on how the environment had affected its preservation would help unravel ...
Blood 46: 253-259, 1975 Beutler,E. Preservation of liquid red cells. In: Rossi,E.C.; Simon,T.L.; Moss,G.S., eds. Principles of ... Blood 14: 103-139, 1959 Beutler, E: The glutathione instability of drug-sensitive red cells. A new method for the in vitro ... This work hinged on his demonstration that red blood cell glutathione was unstable to oxidative stress. Later, he was to ... This he accomplished by showing that two populations of erythrocytes exist in the blood of African American women who are ...
ISBN 978-0-942287-02-8. Librizzi L; Janigro D; De Biasi S; de Curtis M (Oct 2001). "Blood-brain barrier preservation in the in ... In the movie Blood Diner, two cannibal brothers bring their uncle's (isolated) brain back to life to help them in their quest ... In the episode "The Night of the Druid's Blood", one of James West's old tutors is killed and West discovers that it is Dr ... An isolated brain is a brain kept alive in vitro, either by perfusion or by a blood substitute, often an oxygenated solution of ...
This finding had enormous impact on the preservation of blood for transfusion therapy. 1939 - Dupont Guerry III, M.D. intern, ... 1935 - 1967 - Alfred Chanutin, Ph.D., professor and chair of biochemistry, discovered the role of red blood cell 2,3- ...
Rous, Peyton; Turner, J. R. (1916). "The preservation of living red blood cells in vitro : i. Methods of preservation". Journal ... At the time, blood transfusion was by direct person-to-person so that the preservation method allowed transfusion in the ... Rous, Peyton; Turner, J. R. (1916). "The preservation of living red blood cells in vitro: ii. The transfusion of kept cells". ... He and Joseph R. Turner studied methods to make use of blood types for blood transfusion. During World War I, they developed a ...
The Preservation of the Formed Elements and of the Proteins of the Blood. 1949. American Journal of Diseases of Children. ... Her research at the University of Pennsylvania, where she was a professor of clinical pathology, involved blood groups, blood ... was a distinguished research physician who co-discovered the life-saving blood test for the Rh blood factor (with Louis K. ... She published a book, Topics in Blood Banking, in 1974. She received the Emily Cooley Memorial Award from the American ...
... "preservation of the purity of genes and blood"; according to him, mixed-race offspring, such as Jews and Gypsies whom he ... and especially within the blood; the soul, that is to say the ancestral spirits, are believed to live in the blood of their ... A true Slav is held to be one who "glorifies his blood", "glorifies his veins". Devotion to this idea is expressed at the level ... Bezverkhy was in favour of the preservation of distinct races, and at the same time he preached against the domination of some ...
Rous, Peyton; Turner, J. R. (1916). "The preservation of living red blood cells in vitro : i. Methods of preservation". Journal ... A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood ... Several types of blood transfusion exist:[citation needed] Whole blood, which is blood transfused without separation. Red blood ... "Circular of Information for the use of Human Blood and Blood Components" (PDF). AABB, ARC, America's Blood Centers. p. 16. ...
A Pelomedusoid Turtle from the Paleocene-Eocene of Colombia Exhibiting Preservation of Blood Vessels and Osteocytes. Journal of ...
A Pelomedusoid Turtle from the Paleocene-Eocene of Colombia Exhibiting Preservation of Blood Vessels and Osteocytes. Journal of ...
A Pelomedusoid Turtle from the Paleocene-Eocene of Colombia Exhibiting Preservation of Blood Vessels and Osteocytes. Journal of ...
Organs are therefore fully drained of blood, flushed with cool preservation solution, and removed from the body. In an isolated ... In the next step, the aorta is cross-clamped, cutting off blood supply to the organs. Once blood and oxygen supply to an organ ... In addition to HLA and PRA typing, the complete blood count (CBC), coagulation profile, complete metabolic panel, and ABO blood ... ABO blood types also matched the general population, with 31% A, 14% B, 5% AB, and 50% O. In 2004, the average waiting period ...
A Pelomedusoid Turtle from the Paleocene-Eocene of Colombia Exhibiting Preservation of Blood Vessels and Osteocytes. Journal of ...
6. Hesse U.J., et al.: Organ preservation with HTK and UW solution. Pabst Sci. Publishers, D-49525 Lengerich, 1999. 7. Hatano E ... A 2021 meta-analysis demonstrated no statistical advantage of HTK over blood or other crystalloid cardioplegias during adult ... Safety and efficacy of living donor liver preservation with HTK solution. Transplant Proc. 2005;37:316-319. 3. Agarawal A., et ... 5. de Boer J., et al.: Eurotransplant randomized multicenter kidney graft preservation study comparing HTK with UW and Euro- ...
Additionally, thick blubber deposits and intricate blood vessels in the flippers and legs assist in the preservation of heat. ...
It continues to be used today in blood-collection tubes and for the preservation of blood in blood banks. The citrate ion ... chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism. Recently, ... Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood ...
FFP is made by centrifugation of whole blood or apheresis device followed by freezing and preservation. The use of plasma and ... is a blood product made from the liquid portion of whole blood. It is used to treat conditions in which there are low blood ... Risks of transfusion transmitted infections are similar to that of whole blood and red blood cells. ... In the United States it refers to the fluid portion of one unit of whole blood that has been centrifuged, separated, and frozen ...
Pattern I The scar presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes, but no signs ... Pattern II The scar presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes, as before, ... The demyelinating lesion presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes and signs ... This is followed by the blood-brain barrier (BBB) breakdown. BBB is a tight vascular barrier between the blood and brain that ...
... that was injected into Xin Zhui's still existing blood vessels to assure her preservation. Her funerary banner had Han dynasty ... All her organs and blood vessels were also intact, with small amounts of Type A blood being found in her veins. There was hair ... This preservation allowed doctors at Hunan Provincial Medical Institute to perform an autopsy on 14 December 1972. Much of what ... Amare, Verity (5 November 2021). "Blood in Her Veins: 2,000-Year-Old Mummy Looks Like She Recently Died". Medium. Bonn-Muller, ...
"The limits of Burgess Shale-type preservation: assessing the evidence for preservation of the blood protein hemocyanin in the ... Javier Luque; Sarah Gerken (2019). "Exceptional preservation of comma shrimp from a mid-Cretaceous Lagerstätte of Colombia, and ... Javier Ortega-Hernández; Rudy Lerosey-Aubril; Stephen Pates (2019). "Proclivity of nervous system preservation in Cambrian ... "Exceptional preservation of mid-Cretaceous marine arthropods and the evolution of novel forms via heterochrony". Science ...
Preservation of the purity of the Sun's blood was one of the reasons for the brother-sister marriage of the Inca king. The Inca ... The daughter of Antiochus III and Laodice III, Laodice IV, married her two full-blooded older brothers, Antiochus and Seleucus ... Marriage with a family member not related by blood was also regarded as contravening morality and was therefore incest. One ... These copulations were thought to maintain the purity of the royal blood. Another reason for these familial unions was to ...
He did research on blood transfusion, nephritis, pertussis, the preservation of bacteria in vacuo by freeze drying, and ... Brown, James Howard (1919). The Use of Blood Agar for the Study of Streptococci. Reid, Roger D.; Schaub, Isabelle G.; Brewer, ...
Blood preservations are transported, where weight and transport duration matter as well as preventing haemolysis caused by ... However, they have been further developed in the 21st century in places such as hospitals, to send blood samples and the like ...
Aswad, Jem (5 April 2019). "Album Review: Weyes Blood's 'Titanic Rising'". Variety. Archived from the original on 15 June 2021 ... Neill, Andy (2018). "The Kinks Are the Village Green Preservation Society". The Kinks Are the Village Green Preservation ... 1960s portal Rock music portal Preservation Act 1, 1973 concept album by the Kinks Preservation Act 2, 1974 concept album by ... "The Village Green Preservation Society [Super Deluxe Edition] - The Kinks". AllMusic. Archived from the original on 19 June ...
Recreation and Historic Preservation. Archived from the original on 2011-12-10. Retrieved 2009-06-14.See also: "Accompanying 10 ... Blood lived in the house until 1875. A few years before his death, one of his sons, C. Jackson Blood, served as town supervisor ... Jackson Blood came to the area before Orleans County had even been formed, in 1815, as a young man. He bought a farm near the ... Blood, a prominent citizen of the surrounding Town of Yates in its early years, built the house with cobblestones he and his ...
Muncey's blood samples taken during the autopsy were kept in test tubes without preservation. They said that in such conditions ... Blood vials in hot conditions (such as a car trunk in the summer) can blow open. By the time the blood reached the FBI it had ... Muncey's blood, found on House's pants. House's attorneys argued that his pants were contaminated with samples of blood taken ... Blood, moreover, was found to have seeped onto one corner of the foam box and onto packing gauze inside the box below the vials ...
They are similar to pattern-II multiple sclerosis with T-cells and macrophages surrounding blood vessels, preservation of ...
Read reviews of private cord blood banks from parents who have stored their babys cord blood. ... More cord blood resources. Find out more about cord blood and its newborn stem cells in our overview of cord blood banking ... Cord Blood Registry… there are different packages depending on what you want to store. I only did blood. But you can do blood ... The top newborn stem cell preservation and cord blood bank for parents is CBR. According to a series of 2022 BabyCenter Surveys ...
Blood sample collection and preservation. The sample collection for the LUCAS cohort was performed at the time of the screening ... 3 and Methods). We examined these changes in PCAWG lung tumors with matched normal blood cells (n = 31), as blood cells ... For the liver cancer cohort, venous peripheral blood was collected in one K2-EDTA tube. Within 2 h of blood collection, tubes ... White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer. Nat. Commun. 11, 525 (2019). ...
Preservation of Blood Platelets. US Patent Number 5,876,676, issued March 2, 1999. 7. Stossel, TP, Hartwig, JH, Hoffmeister, KM ... Molecular basis of white blood cell motility. In: The Molecular Basis Of Blood Disorders, G Stamatoyannopoulos, AW Nienhuis, PW ... Blood. 2015;125:1116-25 155. Kumar, AA, Chunda-Liyoka, C, Hennek, JW, Mantina, H, Ryan Lee, SY, Patton, MR, Sambo, P, Sinyangwe ... Blood. 1980; 56:442-447. 55. Crowley CA, Curnutte JI, Rosin RE, Andre-Swartz J, Gallin JI, Klempner M, Snyderman R, Southwick ...
... surgeon who helped improve blood plasma preservation with blood banks. ... Drews dissertation topic was: "Banked Blood: A Study in Blood Preservation". Part of his research allowed him to open an ... Charles Drews improvements in blood plasma preservations?. About Post Author. Netert Aset After surviving and thriving from ... Drews significant contributions to the preservation of blood plasma hits home for me personally because I have been a ...
Safe blood and blood products : manual on the management, maintenance and use of blood cold chain equipment. by World Health ... Safe blood and blood products : manual on the management, maintenance and use of blood cold chain equipment..Online access: ... of Blood Safety and Clinical Technology.. Material type: Text; Format: print ; Literary form: Not fiction Publication details: ... of Blood Safety and Clinical Technology.. Material type: Text; Format: print ; Literary form: Not fiction Publication details: ...
Cord Blood Preservation By JustMommies staff. Why Preserve Cord Blood? Why do we buy life insurance? In order to guard against ... It can be detected by a blood test around eight to eleven days past ovulation. HCG maintains the corpus luteum, which is ... Preserving your babys cord blood is better than a life insurance policy. It can potentially preserve the health of the ones ... How Rh negative blood impacts your pregnancy and how to prevent incompatibilities. ...
Can HLHS be Treated by Preservation of The Cord Blood Stem Cells?. The developing genre of tissue engineering tends to build ... These remedies maintain an optimum level of blood cholesterol and bring about a long-lasting cure with added benefits of no ... Suffering from health problems due to high levels of LDL cholesterol in the blood? If yes, you should take homeopathic remedies ... more and more belief on the cord-blood banking as just by replacing a part of damaged cells by the cryopreserved stem cells ...
Hubei Xindesheng Material The company has formed a high-tech enterprise led by blood collection additives, in vitro diagnostic ... Composition and use of cell preservation solution. The so-called cell preservation solution is a general-purpose cell ... heparin lithium comes from the small intestine of pigs - used for blood collection and blood gas testing ... Blood collection tube additives. Chemiluminescent reagents. Chromogenic substrate reagents. Biological buffers. Enzyme ...
Rowe, A. W., Eyster, E. & Kellner, A. Liquid nitrogen preservation of red blood cells for transfusion: A low glycerol - Rapid ... Pi, CH., Yu, G., Petersen, A. et al. Characterizing the "sweet spot" for the preservation of a T-cell line using osmolytes. Sci ... Characterizing the "sweet spot" for the preservation of a T-cell line using osmolytes. *Chia-Hsing Pi1 na1, ... Glycerol has been used to preserve red blood cells26,27. None of these studies have found a single molecule capable of ...
Netripples Cord Blood Bank Management System Software is a comprehensive solution designed to automate the activities of the ... Cord Blood Bank. It is designed with a easy-to-use user interface. System has the capability to administer the total enterprise ... Blood Banks. Voluntary Blood Bank Ideal Blood Bank (Voluntary Blood Bank + HRM) Badar Blood Bank (Ideal Blood Bank + Finance) ... Badar Blood Bank Arabic Version Voluntary Blood Bank Web Version Badar Blood Bank Web Version Total Blood Bank Web Version ...
2008-2010, Development of Longer preservation of Blood Using Antifreeze Molecules Derived from Polar Organisms (08-10) / Kim, ...
Patients taking the oral blood pressure medication not only required less daily insulin two years after first diagnosis of the ... Parkinsons Medication Improved Blood Pressure in Teens With Type 1 Diabetes. Dec. 6, 2022 Teens with Type 1 diabetes who took ... But the preservation of some beta cell function is promising. "In humans with Type 1 diabetes, even a small amount of preserved ... To replace that, patients must take exogenous insulin by shots or pump and are at risk of dangerous low blood sugar events. ...
See Blood - Collection and preservation; Organ and tissue donation; Organ and tissue donation registry See Alberta organ and ...
Preservation of erythrocytes in a dried state offers a potential solution to challenges faced with blood storage, and ... Preservation of erythrocytes in a desiccated state for storage at ambient temperature could simplify blood transfusions in ... However, red blood cells (RBCs) can only be stored for a maximum of 42 days at 4 °C, which poses a significant barrier to blood ... Red blood cells (RBCs) must be continuously maintained at 4 °C, which poses a significant barrier to blood transfusions in far- ...
Preservation of avian blood and tissue samples for DNA analyses. Can. J. Zool. 69: 82-90. Google Scholar ... Four 2.0 mm biopsies and 1.0 cc per kilogram of whole blood were collected from each sedated animal and immediately stored in ...
The procedures provided emboli trapping with preservation of blood flow through the lumen. The procedures included suture ... As it ascends to the right of the aorta and anterior to the spine retroperitoneally, the IVC receives blood from the lower ... Blood Adv. 2020 Oct 13. 4(19):4693-738. [QxMD MEDLINE Link]. [Full Text]. ...
Bean Dwarf Freds (AKA Tiger) , Members Only Preservation Packet. $4.90. Read more. ... Categories: All Vegetables, Beetroot, Beetroot, chard and spinach, Chenopodaceae, Seeds Tags: Beetroot, Bulls Blood, heritage ...
The procedures provided emboli trapping with preservation of blood flow through the lumen. The procedures included suture ... As it ascends to the right of the aorta and anterior to the spine retroperitoneally, the IVC receives blood from the lower ... Blood Adv. 2020 Oct 13. 4(19):4693-738. [QxMD MEDLINE Link]. [Full Text]. ...
The other was the discovery of soft-tissue preservation of blood vessel-like structures within the same individual. Perhaps ... She investigated hypothesized red blood cells in another Tyrannosaurus rex specimen which turned up evidence of the iron heme ... Schweitzer has been researching the nature of molecular and soft-tissue preservation in dinosaurs and some early bird material. ... Schweitzers early research into preservation of soft tissue components began as a graduate student at Montana State University ...
Umbilical cord blood banking in Oregon is an amazing frontier of medical science - find out everything here! ... Riverside, Oregon - Cord Blood Preservation. umbilical cord blood stem cells in Riverside Oregon ... umbilical cord blood stem cells in Riverside OR on a map. *private cord blood banks in Elmo UT ... Umbilical cord blood stem cells in Riverside Oregon. Umbilical cord blood banking of Riverside is an amazing frontier of ...
... cord blood donation hospitals. Umbilical cord blood banking in Pennsylvania is an amazing frontier of medical science - find ... Herndon, Pennsylvania - Cord Blood Preservation. cord blood donation hospitals in Herndon Pennsylvania ... cord blood donation hospitals in Herndon PA on a map. *cord blood donation in Tappen ND ... Cord blood donation hospitals in Herndon Pennsylvania. Umbilical cord blood banking of Herndon is an amazing frontier of ...
Controlled reactive professional phagocytic leukocytes in immunodeficient mice allowed for sizeable human blood chimerism and ... Controlled reactive professional phagocytic leukocytes in immnuodeficient mice allowed sizeable human blood chimersism and ... Rowe AW, Eyster E, Kellner A. Liquid nitrogen preservation of red blood cells for transfusion; a low glycerol-rapid freeze ... The packed huRBCs were provided by the Interstate Blood Bank (Chinese blood bank). Blood was taken from donors with no history ...
... Am J Physiol. 1988 Jun;254(6 Pt 1):E700-7. ... Alanine / blood * Blood Glucose / metabolism* * Fasting* * Humans * Insulin / blood * Insulin / physiology* * Keto Acids / ...
Blood detection, NSR adhesive curing, night vision preservation, biofluorescence ... BLUE 470nm: Blood detection, NSR adhesive curing, night vision preservation, biofluorescence.. * UV 395nm: Urine and pet stains ...
The breakthrough could have major implications for long-term safe preservation of everything from blood cells and organs to the ... that red blood cells can be stored. At present, red blood cells can be stored for a maximum of 42 days. Using this new approach ... A new way to freeze water could help transform organ preservation. Impact Lab. , Biotech. , A new way to freeze water could ... We also want to translate] our approach to the preservation of exotic cell types and organs, such as the liver, since our ...
Charles Drew researched the preservation of blood plasma. He developed methods to efficiently store large quantities of blood ... Charles Drew developed Americans first large-scale blood banks during World War II. He resigned when the armed forces ... restricted blood donations from African Americans.. Jewel Plummer Cobb (1924 - 2017). Cell Biologist , Cancer Researcher , ...
Likely mechanisms whereby supplementation of the NO pathway enhanced preservation included increased blood flow to the ... blood flow system using the three thrombin inhibitors recombinant hirudin, Ro 46-6240, and heparin. Under venous blood flow ... High blood pressure is one of the major risk factors for atherosclerosis. In this study, we examined the effects of pressure on ... The data, which also suggest that the adult peripheral blood CD5+ B cell population may be dominated by a small number of B ...
  • The top newborn stem cell preservation and cord blood bank for parents is CBR. (
  • Once you decide to preserve your newborn's stem cells by banking your baby's cord blood in a private bank, choosing a cord blood bank is your next important decision. (
  • Preserving your baby's cord blood is better than a life insurance policy. (
  • The other was the discovery of soft-tissue preservation of blood vessel-like structures within the same individual. (
  • More recently, Dr. Schweitzer has been researching the nature of molecular and soft-tissue preservation in dinosaurs and some early bird material. (
  • Demineralization assays, utilizing weak acids to isolate organics from biomineralized tissues, have recently been applied with increasing frequency to explore soft tissue preservation in fossils, revealing frequent retention of cells and other pliable microstructures in fossil bones. (
  • Although these findings hint at possible controls on cellular and soft tissue preservation in fossil bones, they should be viewed cautiously as they are demonstrably biased by uneven sampling. (
  • We also want to translate] our approach to the preservation of exotic cell types and organs, such as the liver, since our center already has a very active cell and organ preservation research thrust. (
  • Organ Preservation is supplying line for organ transplantation. (
  • The global organ preservation market is majorly driven by the high prevalence of organ failures, increasing advancement in surgeries, increasing number of transplantation procedures, and growing penetration by market players. (
  • However, factors such as high cost of organ preservation and its transplantation procedures, unavailability of the suitable donor as well as the development of organs by stem cell therapy are likely to hamper the growth of the market. (
  • The Organ Preservation market is expected to register a CAGR of 8.0% during the forecast period. (
  • The Americas dominates the global organ preservation market owing to the increasing geriatric population, which eventually leads to the increasing patient pool because of their vulnerability to organ failures. (
  • Additionally, the increasing burden of diabetes, cardiovascular disorder, diabetic nephropathy, and obesity rate along with rising government initiatives for the research and development of innovative and advanced products are likely to enhance the growth of organ preservation in the North American region. (
  • This depicts the rising need for organ transplantation which is going to spur the organ preservation market growth. (
  • Additionally, the increasing government support and increasing healthcare infrastructure along with the increasing demand for minimally invasive treatments are driving the growth of the Organ Preservation market in Europe. (
  • These factors are likely to drive the growth of the organ preservation market. (
  • Asia Pacific is the fastest growing market for organ preservation whose growth is attributed to the rising population and improving the standard of living. (
  • But after talking with an orthopedic team that was determined to work to save Noah's foot, the family agreed to a complicated limb reconstruction process that involved multiple surgeries to clean out the wound, re-attach severed toes, transplant a portion of Noah's back muscle and skin over the foot to cover the wound, and reconnect blood vessels to restore blood flow. (
  • Osteocytes, blood vessels, and fibrous/proteinaceous matrix each exhibit bimodal recovery patterns in which most fossil bones either yield many or none of these microstructures. (
  • This module includes Blood Donation Center Lab, Microbiology Lab Modules along with various reports related to this module for view and printing purposes. (
  • You may even save money by booking in advance (cord blood donation hospitals). (
  • Cord blood collection for donation or for private preservation is not allowed. (
  • Association for the Advancement of Blood & Biotherapies (AABB) - formerly known as the American Association of Blood Banks, the AABB is a not-for-profit organization 'representing individuals and institutions involved in the field of transfusion medicine and biotherapies. (
  • At Columbia University he furthered his studies in relation to blood chemistry and preservation, fluid balance and transfusion with John Schuder. (
  • Transfusion of blood preserved by freezing / by S. Sumida. (
  • Blood transfusion : a technical and clinical care / Syed Abdul Mujeeb. (
  • This module includes Patient/ Donor Registration, Invoice & Billing, Packing Information, Cord Blood Issuues, Transplant Center Feedback Information, Dispose Bags, CBU Barcode Status, Post Transfusion Information screens along with various reports related to this module for view and printing purposes. (
  • It is suitable for the collection, preservation and transportation of various common virus samples. (
  • This module includes This module includes Samples Sent to Labs, Cord Blood Processing, LNT Long Term Storage, Results Verification, CD34 Pre/Post Processing Test Results, Retrieve Units, Disposal of Units, Barcode Search. (
  • To examine changes in circulating proteins in response to verapamil treatment, the researchers used liquid chromatography-tandem mass spectrometry of blood serum samples from subjects diagnosed with Type 1 diabetes within three months of diagnosis and at one year of follow-up. (
  • We are now focused on increasing the volume of the preserved liquid phase from the 1-100 milliliter range to 500 milliliters to enable mass preservation of samples," Usta continued. (
  • We offer a range of essential equipment, including a level 2 biohood, a freezer (-80 degrees Celsius), and a refrigerator, allowing for the proper handling and preservation of samples such as blood, urine, saliva, and stool. (
  • A Prewash Solution is provided to help remove contaminants that are associated with aged (older than 24 hours) whole blood samples. (
  • components · information needed on requisitions or forms · handling urgent requests · collection, labeling, preservation and transport · safety practices (leaking or broken containers, contaminated forms, other biohazards) · evaluating, processing, and tracking samples · storage, retention, and disposal. (
  • To help you choose, BabyCenter looked at real-parent recommendations, surveyed moms about private banks, and created an overview of reviews for BabyCenter parents' top five cord blood banks. (
  • Rounding out the top five most popular private cord blood banks for surveyed BabyCenter moms and dads are Americord, Cryo-Cell, MiracleCord, and Viacord. (
  • There are some very successful Herndon public cord blood banks as well. (
  • Therefore, you will need to be able to compare cord blood banks. (
  • Here are some suggestions to help you compare cord blood banks effectively. (
  • The cord blood banks you select should be financially secure and should be a profit making concern. (
  • This will be our second time using Cord Blood Registry. (
  • The developing genre of tissue engineering tends to build more and more belief on the cord-blood banking as just by replacing a part of damaged cells by the cryopreserved stem cells causes the new ones to redevelop and take the place of the old damaged portions of the cells. (
  • Dr. Schweitzer's early research into preservation of soft tissue components began as a graduate student at Montana State University in the 1990's. (
  • The physiological responses to haemorrhage in mammals are aimed at the preservation of blood pressure and tissue perfusion. (
  • Success-the preservation of a damaged limb-depends on ensuring that good blood supply continually flows into the damaged area, which keeps alive the tissue grafts that are placed to cover a wound. (
  • Charles Richard Drew (June 3, 1904- April 1,1950) was an African American doctor and surgeon who helped make vital contributions to the medical field by way of improved blood plasma preservation through blood banks. (
  • However, factors controlling long-term preservation of such labile structures remain mysterious. (
  • In 2018, Shalev and colleagues reported the benefits of verapamil in a one-year clinical study of Type 1 diabetes patients, finding that regular oral administration of verapamil enabled patients to produce higher levels of their own insulin, thus limiting their need for injected insulin to regulate blood sugar levels. (
  • In an experiment, the researchers demonstrated that it is possible to more than double the amount of time, from the clinical standard approach, that red blood cells can be stored. (
  • In addition, this quality measure incorporates best practices on blood culture collection from the Clinical & Laboratory Standards Institute (CLSI) and the Infectious Disease Society of America (IDSA) . (
  • Your hospital or clinical setting should instruct healthcare staff to collect at least two blood culture sets (total volume of 40-60 mL) within a 24-hour period by peripheral venipuncture prior to antibiotic administration, if possible. (
  • A cord blood bank that is properly certified and accredited to professional organizations will follow industry best practices. (
  • CDC developed this quality measure to promote blood culture best practices and improve the laboratory diagnosis of bloodstream infection. (
  • Benefits of the blood pressure medication verapamil include delayed disease progression, lowered insulin requirements and preservation of some beta cell function. (
  • Patients taking the oral blood pressure medication not only required less daily insulin two years after first diagnosis of the disease, but also showed evidence of surprising immunomodulatory benefits. (
  • To replace that, patients must take exogenous insulin by shots or pump and are at risk of dangerous low blood sugar events. (
  • CHGA levels were also easily measured directly in serum using a simple ELISA assay after a blood draw, and lower levels in verapamil-treated subjects correlated with better endogenous insulin production as measured by mixed-meal-stimulated C-peptide, a standard test of Type 1 diabetes progression. (
  • Early detection of human immunodeficiency virus on dried blood spot specimens: sensitivity across serial specimens. (
  • Dr. Drew's significant contributions to the preservation of blood plasma hits home for me personally because I have been a recipient of donor blood plasma for a lupus flare through the process of plasmapheresis (plasma exchange). (
  • The breakthrough could have major implications for long-term safe preservation of everything from blood cells and organs to the food we eat. (
  • Extensive research should be done preservation solutions to increase their efficacy to protect the organs from cellular damage and maintain its metabolic rate. (
  • Bleeding in sheep resulted in the appearance of large erythrocytes in peripheral blood (Wintour et al . (
  • Poorly controlled blood sugar levels can result in peripheral neuropathy and limited blood flow to legs and toes. (
  • An antibiotic stewardship team including laboratory professionals discussing ways to improve blood culture collection in their hospital. (
  • Using the methods provided in this quality tool to calculate the BCC and single-set rates will help meet this standard and ensure optimal blood culture collection. (
  • Example of some blood culture collection supplies. (
  • To achieve an optimal volume, the blood culture collection standard of practice is to collect two to four blood culture sets from adult patients with a suspected blood stream infection in the evaluation of each septic episode (i.e., 24 hours). (
  • Laboratory professionals reviewing a blood culture collection SOP on a dedicated electronic device. (
  • Gelsolin is also an abundant extracellular protein that circulates in blood plasma, and Stossel established that it is a component of innate immunity that promotes host antimicrobial activity and prevents the potentially lethal dissemination of inflammation. (
  • Dr. Drew's calling for the urgency of his invention of preserving blood plasma was in September of 1940 when New York area hospitals participated in the Blood for Britain project in preparation for World War II. (
  • Dr. Drew received a U.S. Patent for Blood Plasma Preservation (U.S. Patent No. 2,389,355). (
  • Have you/do you know someone who has benefitted from Dr. Charles Drew's improvements in blood plasma preservations? (
  • While earning his doctorate, Charles Drew researched the preservation of blood plasma. (
  • He developed methods to efficiently store large quantities of blood plasma. (
  • The magnitude of haemorrhage was expressed as percentage of initial total blood volume after plasma volume determination by dye dilution. (
  • Stossel's research included studies of white blood cell structure function in health and disease but predominantly focused on the molecular mechanism of how cells move and change shape. (
  • Part of his research allowed him to open an experimental blood bank at Presbyterian Hospital. (
  • In such settings, nurses can be performing health assessments by checking blood pressure or cholesterol readings, conducting teaching sessions and disseminating health information to a group of rural residents, providing counsel and referral for an injured farm worker, or reviewing medical records for injury surveillance research data. (
  • For Xiaobai who is new to the knowledge of virus transport media , it is not so easy to distinguish the difference between virus transport media and cell preservation solution. (
  • The so-called cell preservation solution is a general-purpose cell cryopreservation solution. (
  • Cell cryopreservation is an important technical means for cell culture, introduction, preservation and to ensure the smooth progress of the experiment. (
  • In summary, the composition and use of virus transport media and cell preservation solution are completely different, and Desheng does not produce cell preservation solution. (
  • is a comprehensive solution designed to automate the activities of the Stem Cell and Cord Blood. (
  • After moderate haemorrhage, a low PCV is remarkably well tolerated because of compensatory mechanisms such as increase in concentration of 2,3-diphosphoglycerate in red blood cell (Ganong, 2003). (
  • Erythropoietin secretion from the kidneys increases in response to blood loss to stimulate erythropoiesis by the bone marrow (Hillman, 1995) and the iron supply to the red cell production usually reflects the severity of the anaemia (Jain, 1993). (
  • Heck, who knows - although this approach studiously avoids actual freezing, maybe it could prompt advances in the kind of long-term cryogenic preservation process that scientists, sci-fi authors, and, allegedly, Walt Disney have speculated about for years. (
  • Stossel was the author of almost 300 publications, including co-authoring two textbooks, Haematology: A Pathophysiological Approach (1984) and Blood: Principles and Practice of Hematology (1997) and the consumer book Pharmaphobia: How the Conflict of Interest Myth Undermines American Medical Innovation (2015). (
  • 1987). Haemorrhage resulted in a fall followed by a partial recovery of arterial blood pressure and significant rise of hepatic artery blood flow in rats (Darlington and Tehrani, 1997). (
  • Introduction of several mouse strains with genetic immune deficiencies has greatly benefited the development of a small laboratory animal model ( 7 - 15 ) to study the asexual blood stage infection of P. falciparum . (
  • The volume of blood collected is critically important to the laboratory diagnosis of bloodstream infection, which generally requires two or more sets to achieve. (
  • Charles Drew developed American's first large-scale blood banks during World War II. (
  • False negative blood culture results due to inadequate volumes of blood can result in misdiagnosis, delay therapy, and put patients at heightened risk of morbidity and mortality from bacteremia. (
  • The United States Food and Drug Administration approved verapamil for the treatment of high blood pressure in 1981. (
  • Uses include blood-clotting products, brewing refining agents, pool water clarifiers, food preservation, textile and fabric components, weight loss supplements and agricultural fungicide treatments. (
  • Additional uses of commercial nitrate and nitrite include food preservation and the production of munitions and explosives. (
  • Accreditation means the AABB has worked with and reviewed a company's approach to 'the quality and safety of collecting, processing, testing, distributing and administering blood and blood products. (
  • Many people in Herndon, Pennsylvania have now begun to anticipate scientific discovery and plan to store the cord blood of their baby so that the basic material is available in the future. (
  • The expected yields of genomic DNA will vary depending on the amount and nature of the starting material used (for example, 4 to 10 μg of RNase A-treated DNA can be isolated from 200 μl of fresh whole blood in less than one hour). (
  • Despite the heterogeneity of the studies, some evidence suggests that ridge preservation procedures are efficient in limiting the postextraction dimensional loss of the ridge and are accompanied by a different degree of bone regeneration, with varied amounts of residual graft material particles. (
  • This type of cord blood storage in Herndon, Pennsylvania is of course only possible in a private cord blood bank. (
  • Selecting a private cord blood bank is not something to be done casually. (
  • To minimize this bias, sentinel surveillance, selecting sentinel populations where blood is already drawn for other purposes, was established, as recommended by the World Health Organization (WHO) [2]. (
  • The focus for nurses who practice in public and occupational health is not as much on the individual and a disease state as it is on the group or population and the preservation of health through prevention. (
  • Guide to the preparation, use and quality assurance of blood components : recommendation no. (
  • According to the FDA, 'Establishments that perform any of the manufacturing steps for cord blood must register with FDA and list their products and each of the manufacturing steps they perform. (
  • Safe blood and blood products : manual on the management, maintenance and use of blood cold chain equipment. (
  • Most processed meats contain pork or beef, but may also contain other meats including poultry and offal (e.g. liver) or meat by-products such as blood. (
  • Laboratory analysis of blood cultures is vital to the accurate and timely diagnosis of bloodstream infections. (
  • Severe blood loss threatens homeostasis as it acutely decreases blood volume and can lead to cardiovascular collapse, hypovolaemic shock and death (Hillman, 1995). (
  • Umbilical cord blood banking of Herndon is an amazing frontier of medical science that is being explored rapidly and new concepts and process are emerging daily. (
  • Why did parents choose a cord blood bank? (
  • In this manner, thepublic cord blood bank offers a valuable service to the public. (
  • Agreed, cord blood storage is a relatively new service, but the bank in Pennsylvania you select should have been active in the field of medical sample preservation for some time. (
  • The authors provide the most up-to-date information available on key areas of DUI law in South Carolina including: DUI Investigations, Driving and Field Sobriety Testing, Drug Recognition, Evaluation and Chemical Testing, Blood Alcohol Calculations, Pre-trial Investigations and Motions, Practice, Plea Offers and Agreements, DUI Trial Procedures, and more. (
  • Several techniques and materials have been suggested for alveolar ridge preservation (ARP) after dental extraction and before implant placement. (
  • Once accepted later on, African American blood was still separated from white blood. (
  • The primary mediator of the blood pressure response in animals is increased activity of the sympathoadrenal system in sheep (Block et al . (
  • Processed meat refers to meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavour or improve preservation. (
  • A human blood chimeric mouse could serve to harmonize in vitro P. falciparum cultivation and in vivo studies carried out in rodent animal models. (
  • Despite his expertise in the area of blood banking, the Red Cross, who participated in the program, refused African American blood donations, including that of Dr. Charles Drew himself. (
  • They accept donations of cord blood from any mother and offer it to any sick person who will benefit from the transplant. (
  • He resigned when the armed forces restricted blood donations from African Americans. (
  • The reticulocyte response to acute blood loss is highly variable among species (Tyler and Cowell, 1996). (
  • La surveillance du VIH a été mise en route avec la réalisation d'études sérologiques ad hoc dans certains groupes de population. (
  • En dehors de la surveillance, de nombreux autres groupes de population sont soumis à un test VIH, principalement aux fins de dépistage. (