Digestive System and Oral Physiological Phenomena
Reproductive and Urinary Physiological Phenomena
Musculoskeletal and Neural Physiological Phenomena
Circulatory and Respiratory Physiological Phenomena
Integumentary System Physiological Phenomena
Sports Nutritional Physiological Phenomena
Reproductive Physiological Phenomena
Physiological Phenomena
Elder Nutritional Physiological Phenomena
Urinary Tract Physiological Phenomena
Digestive System Physiological Phenomena
Ocular Physiological Phenomena
Nervous System Physiological Phenomena
Respiratory Physiological Phenomena
Skin Physiological Phenomena
Plant Physiological Phenomena
Cardiovascular Physiological Phenomena
Maternal Nutritional Physiological Phenomena
Nutritional Physiological Phenomena
Vibration
Hand-Arm Vibration Syndrome
Raynaud Disease
National Institute for Occupational Safety and Health (U.S.)
Mechanical stimulation regulates voltage-gated potassium currents in cardiac microvascular endothelial cells. (1/429)
Vascular endothelial cells are constantly exposed to mechanical forces resulting from blood flow and transmural pressure. The goal of this study was to determine whether mechanical stimulation alters the properties of endothelial voltage-gated K+ channels. Cardiac microvascular endothelial cells (CMECs) were isolated from rat ventricular muscle and cultured on thin sheets of silastic membranes. Membrane currents were measured with the use of the whole-cell arrangement of the patch-clamp technique in endothelial cells subjected to static stretch for 24 hours and compared with measurements from control, nonstretched cells. Voltage steps positive to -30 mV resulted in the activation of a time-dependent, delayed rectifier K+current (IK) in the endothelial cells. Mechanically induced increases of 97%, 355%, and 106% at +30 mV were measured in the peak amplitude of IK in cells stretched for 24 hours by 5%, 10%, and 15%, respectively. In addition, the half-maximal voltage required for IK activation was shifted from +34 mV in the nonstretched cells to -5 mV in the stretched cells. Although IK in both groups of CMECs was blocked to a similar extent by tetraethylammonium, currents in the stretched endothelial cells displayed an enhanced sensitivity to inhibition by charybdotoxin. Preincubation of the CMECs with either pertussis toxin or phorbol 12-myristate 13-acetate during the 24 hours of cell stretch did not prevent the increase in IK. The application of phorbol 12-myristate 13-acetate and static stretch stimulated the proliferation of CMECs. Stretch-induced regulation of K+ channels may be important to control the resting potential of the endothelium and may contribute to capillary growth during periods of mechanical perturbation. (+info)Validation of haemodialysis recirculation and access blood flow measured by thermodilution. (2/429)
BACKGROUND: Recirculation (R) and access blood flow (Qac) measurements are considered useful indicators of adequate delivery of haemodialysis. It was the purpose of this study to compare measurements of R and Qac obtained by two different techniques which are based on the same principle of indicator dilution, but which differ because of the characteristics of the injection and detection of the different indicators used. METHODS: Recirculation measured by a thermal dilution technique using temperature sensors (BTM, Fresenius Medical Care) was compared with recirculation measured by a validated saline dilution technique using ultrasonic transducers placed on arterial and venous segments of the extracorporeal circulation (HDM, Transonic Systems, Inc.). Calculated access flows were compared by Bland Altman analysis. Data are given as mean +/- SD. RESULTS: A total of 104 measurements obtained in 52 treatments (17 patients, 18 accesses) were compared. Recirculation measured with correct placement of blood lines and corrected for the effect of cardiopulmonary recirculation using the 'double recirculation technique' was -0.02 +/- 0.14% by the BTM technique and not different from the 0% measured by the HDM technique. Recirculation measured with reversed placement of blood lines and corrected for the effect of cardiopulmonary recirculation was 19.66 +/- 10.77% measured by the BTM technique compared with 20.87 +/- 11.64% measured by the HDM technique. The difference between techniques was small (-1.21 +/- 2.44%) albeit significant. Access flow calculated from BTM recirculation was 1328 +/- 627 ml/min compared with 1390 +/- 657 ml/min calculated by the HDM technique. There was no bias between techniques. CONCLUSION: BTM thermodilution yields results which are consistent with the HDM ultrasound dilution technique with regard to both recirculation and access flow measurement. (+info)Surfactant protein A enhances the binding and deacylation of E. coli LPS by alveolar macrophages. (3/429)
Surfactant protein (SP) A and SP-D are involved in multiple immunomodulatory functions of innate host defense partly via their interaction with alveolar macrophages (AMs). In addition, both SP-A and SP-D bind to bacterial lipopolysaccharide (LPS). To investigate the functional significance of this interaction, we first tested the ability of SP-A and SP-D to enhance the binding of tritium-labeled Escherichia coli LPS to AMs. In contrast to SP-D, SP-A enhanced the binding of LPS by AMs in a time-, temperature-, and concentration-dependent manner. Coincubation with surfactant-like lipids did not affect the SP-A-mediated enhancement of LPS binding. At SP-A-to-LPS molar ratios of 1:2-1:3, the LPS binding by AMs reached 270% of control values. Second, we investigated the role of SP-A in regulating the degradation of LPS by AMs. In the presence of SP-A, deacylation of LPS by AMs increased by approximately 2.3-fold. Pretreatment of AMs with phosphatidylinositol-specific phospholipase C had no effect on the SP-A-enhanced LPS binding but did reduce the amount of serum-enhanced LPS binding by 50%, suggesting that a cell surface molecule distinct from CD14 mediates the effect of SP-A. Together the results for the first time provide direct evidence that SP-A enhances LPS binding and degradation by AMs. (+info)Long-term culture of human CD34(+) progenitors with FLT3-ligand, thrombopoietin, and stem cell factor induces extensive amplification of a CD34(-)CD14(-) and a CD34(-)CD14(+) dendritic cell precursor. (4/429)
Current in vitro culture systems allow the generation of human dendritic cells (DCs), but the output of mature cells remains modest. This contrasts with the extensive amplification of hematopoietic progenitors achieved when culturing CD34(+) cells with FLT3-ligand and thrombopoietin. To test whether such cultures contained DC precursors, CD34(+) cord blood cells were incubated with the above cytokines, inducing on the mean a 250-fold and a 16,600-fold increase in total cell number after 4 and 8 weeks, respectively. The addition of stem cell factor induced a further fivefold increase in proliferation. The majority of the cells produced were CD34(-)CD1a- CD14(+) (p14(+)) and CD34(-)CD1a-CD14(-) (p14(-)) and did not display the morphology, surface markers, or allostimulatory capacity of DC. When cultured with granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4), both subsets differentiated without further proliferation into immature (CD1a+, CD14(-), CD83(-)) macropinocytic DC. Mature (CD1a+, CD14(-), CD83(+)) DCs with high allostimulatory activity were generated if such cultures were supplemented with tumor necrosis factor-alpha (TNF). In addition, p14(-) cells generated CD14(+) cells with GM-CSF and TNF, which in turn, differentiated into DC when exposed to GM-CSF and IL-4. Similar results were obtained with frozen DC precursors and also when using pooled human serum AB+ instead of bovine serum, emphasizing that this system using CD34(+) cells may improve future prospects for immunotherapy. (+info)Low-molecular weight heparin restores in-vitro trophoblast invasiveness and differentiation in presence of immunoglobulin G fractions obtained from patients with antiphospholipid syndrome. (5/429)
The present study was designed to investigate the effects of immunoglobulin G obtained from patients with antiphospholipid syndrome (APS) on in-vitro models of trophoblast invasiveness and differentiation. We tested the binding of affinity-purified immunoglobulin G to human primary trophoblast cells. These antibodies affected the invasiveness and differentiation of cytotrophoblast cells after binding to the cell surface. In addition, we determined whether the drugs used to treat APS might be able to restore the trophoblast functions. Low-molecular weight heparin, in a dose-dependent manner, significantly reduced the immunoglobulin G binding to trophoblast cells and restored in-vitro placental invasiveness and differentiation. No effect was observed in the presence of acetylsalicylic acid. These observations may help in understanding the role of these treatments in women with APS. (+info)Partial characterization of apoptotic factor in Alzheimer plasma. (6/429)
We have previously demonstrated that a plasma natriuretic factor is present in Alzheimer's disease (AD), but not in multi-infarct dementia (MID) or normal controls (C). We postulated that the natriuretic factor might induce the increased cytosolic calcium reported in AD by inhibiting the sodium-calcium antiporter, thereby activating the apoptotic pathway. To test for a factor in AD plasma that induces apoptosis, we exposed nonconfluent cultured LLC-PK1 cells to plasma from AD, MID, and C for 2 h and performed a terminal transferase-dUTP-nick-end labeling (TUNEL) assay. The plasma from AD increased apoptosis nearly fourfold compared with MID and C. The effect was dose dependent and the peak effect was attained after a 2-h exposure. Additionally, apoptotic morphology was detected by electron microscopy, and internucleosomal DNA cleavage was found. We inhibited apoptosis by removing calcium from the medium, inhibiting protein synthesis with cycloheximide, alternately boiling or freezing and thawing the plasma, and digesting a partially purified fraction with trypsin. Heating AD plasma to 56 degrees C did not deactivate the apoptotic factor. These results demonstrate the presence of an apoptotic factor in the plasma of patients with AD. (+info)Delayed ischemic preconditioning is mediated by opening of ATP-sensitive potassium channels in the rabbit heart. (7/429)
Cardioprotection from preconditioning reappears 24 h after the initial stimulus. This phenomenon is called the second window of protection (SWOP). We hypothesized that opening of the ATP-sensitive potassium (KATP) channel mediates the protective effect of SWOP. Rabbits were preconditioned (PC) with four cycles of 5-min regional ischemia each followed by 10 min of reperfusion. Twenty-four hours later, the animals were subjected to sustained ischemia for 30 min followed by 180 min of reperfusion (I/R). Glibenclamide (Glib, 0.3 mg/kg ip) or 5-hydroxydecanoate (5-HD, 5 mg/kg iv) was used to block the KATP channel function. Infarct size was reduced from 41.2 +/- 2. 6% in sham-operated rabbits to 11.6 +/- 1.0% in PC rabbits, a 71% reduction (n = 11, P < 0.01). Treatment with Glib or 5-HD before I/R increased the infarct size to 43.4 +/- 2.6 and 37.8 +/- 1.9%, respectively (P < 0.01 vs. PC group, n = 12/group). Sham animals treated with either Glib or 5-HD had an infarct size of 39.0 +/- 3.4 and 37.8 +/- 1.5%, respectively, which was not different from control (40.0 +/- 3.8%) or sham (41.2 +/- 2.6%) I/R hearts. Monophasic action potential duration (APD) at 50% repolarization significantly shortened by 28.7, 26.6, and 23.3% in sham animals during 10, 20, and 30 min of ischemia. However, no further augmentation in the shortening of APD was observed in PC hearts. Glib and 5-HD significantly suppressed ischemia-induced epicardial APD shortening, suggesting that 5-HD may not be a selective blocker of the mitochondrial KATP channel in vivo. We conclude that SWOP is mediated by a KATP channel-sensitive mechanism that may have occurred because of the opening of the sarcolemmal KATP channel in vivo. (+info)Evidence of splanchnic-brain signaling in inhibition of ingestive behavior by middle molecules. (8/429)
Anorexia, nausea, and vomiting are common symptoms of uremic intoxication. Fractions in the middle molecule weight range, isolated from normal urine and uremic plasma ultrafiltrate, inhibit ingestive behavior in the rat. To investigate their site of action and specificity, male rats were injected intraperitoneally, intravenously, or intracerebroventricularly with concentrated fractions of uremic plasma ultrafiltrate or normal urine (molecular weight range: 1.0 to 5.0 kD) and tested for ingestive and sexual behavior. An intraperitoneal injection of 0.5 ml of urine fraction (10:1) or 2.0 ml of uremic plasma ultrafiltrate fraction (25:1) inhibited carbohydrate intake by 76.3 and 45.9%, respectively, but an intravenous injection had no effect. However, intravenous injection of higher doses inhibited carbohydrate ingestion. An intracerebroventricular injection of 5 or 10 microl of urine (20:1) middle molecule fraction inhibited carbohydrate intake by 13.4 and 41.6%, respectively. An injection of 5 or 10 microl of uremic plasma ultrafiltrate (125:1) middle molecule fraction inhibited carbohydrate intake by 22.6 and 49.5%, respectively. Injections of the corresponding fraction from normal plasma ultrafiltrate had no effect. Injection of urine or uremic plasma ultrafiltrate middle molecule fractions did not affect the display of sexual behavior. These results suggest that middle molecule fractions from uremic plasma ultrafiltrate or normal urine act in the splanchnic region and/or brain to inhibit food intake and that the effect is specific for ingestive behavior. (+info)HAVS is typically caused by prolonged exposure to vibrations from hand-held power tools, such as jackhammers, drills, and sanders. The vibrations can cause damage to the blood vessels, nerves, and joints in the hands, leading to the development of HAVS.
There are several risk factors for developing HAVS, including:
1. Prolonged exposure to hand-transmitted vibrations
2. Use of high-vibration tools and equipment
3. Poor tool maintenance and repair
4. Inadequate training on the safe use of tools and equipment
5. Smoking and other cardiovascular risk factors
The symptoms of HAVS can vary in severity and may include:
1. Numbness, tingling, or pain in the hands and fingers
2. Reduced dexterity and grip strength
3. Fatigue and weakness in the hands and arms
4. Tremors or spasms in the hands and fingers
5. Pale or discolored skin on the fingers and hands
6. Decreased sensation in the fingertips
7. Swelling, redness, or warmth in the hands and fingers
If left untreated, HAVS can lead to more severe symptoms, including:
1. Permanent nerve damage
2. Loss of dexterity and grip strength
3. Decreased sensation in the fingertips
4. Finger ulcers and amputations
5. Carpal tunnel syndrome
6. Other neurological disorders
There is no cure for HAVS, but it can be managed with a combination of medical treatment and lifestyle changes. Treatment options may include:
1. Medications to relieve symptoms such as pain and inflammation
2. Physical therapy to improve dexterity and grip strength
3. Lifestyle modifications such as avoiding cold temperatures and taking regular breaks to warm up hands
4. Assistive devices such as gloves, splints, or hand braces
5. Surgery in severe cases to relieve compression on nerves or repair damaged tissue.
Prevention is the best course of action for HAVS, and it involves taking steps to reduce exposure to cold temperatures and other risk factors. Some ways to prevent HAVS include:
1. Using proper protective gear such as gloves, hats, and scarves in cold environments
2. Avoiding prolonged exposure to cold temperatures
3. Taking regular breaks to warm up hands and fingers
4. Exercising regularly to improve circulation and reduce risk factors such as smoking and obesity
5. Maintaining a healthy diet and getting enough sleep.
The exact cause of Raynaud disease is not fully understood, but it is believed to be related to an autoimmune disorder, in which the body's immune system mistakenly attacks healthy tissue. The condition can occur on its own or as a secondary symptom of another underlying medical condition such as scleroderma or rheumatoid arthritis.
Symptoms of Raynaud Disease:
1) Discoloration: Raynaud disease causes the affected areas to turn white or blue in response to cold temperatures or stress.
2) Pain: The constriction of blood vessels can cause pain in the affected areas.
3) Numbness or tingling: The lack of blood flow can cause numbness or tingling sensations in the fingers and toes.
4) Swelling: In severe cases, swelling may occur in the affected areas.
5) Burning sensation: Some people with Raynaud disease may experience a burning sensation in their hands and feet.
Diagnosis of Raynaud Disease:
1) Medical history: A doctor will ask about symptoms, medical history, and any triggers that may cause the condition.
2) Physical examination: The doctor will perform a physical examination to look for signs of discoloration or swelling in the affected areas.
3) Tests: Additional tests such as nailfold capillary microscopy, pulse volume recording and thermography may be ordered to confirm the diagnosis.
Treatment options for Raynaud Disease:
1) Medications: Drugs such as calcium channel blockers, alpha-blockers, and anticoagulants can help to relax blood vessels and improve blood flow.
2) Lifestyle changes: Avoiding triggers such as cold temperatures and taking steps to keep hands and feet warm can help manage the condition.
3) Alternative therapies: Some people with Raynaud disease may find relief with alternative therapies such as acupuncture or biofeedback.
It is important to note that in some cases, Raynaud disease can be a symptom of an underlying autoimmune disorder, such as lupus or scleroderma. If you suspect you have Raynaud disease, it is essential to seek medical attention to rule out any other conditions.
A laboratory infection is an infection that occurs in a healthcare worker or laboratory personnel while working in a laboratory setting, typically with infectious agents such as bacteria, viruses, or fungi. These infections can be acquired through exposure to infected samples, equipment, or surfaces in the laboratory.
The risk of laboratory infection is higher in settings where high-risk agents are handled, such as in the study of highly infectious diseases like Ebola or SARS. The transmission of infectious agents in laboratories can occur through various routes, including:
1. Direct contact with infected samples or materials.
2. Contact with contaminated surfaces or equipment.
3. Inhalation of aerosols generated during procedures such as centrifugation or pipetting.
4. Exposure to infected personnel or animals in the laboratory.
To prevent laboratory infections, healthcare workers and laboratory personnel must follow strict safety protocols, including wearing personal protective equipment (PPE) such as gloves, gowns, and masks, and adhering to proper sterilization and decontamination techniques. Laboratories should also have ventilation systems that filter out infectious agents and should be designed with containment levels to minimize the risk of exposure.
Laboratory infections can have serious consequences for both the individuals involved and the broader community, including the potential for transmitting infectious diseases to others outside of the laboratory setting. Therefore, it is essential to have strict safety protocols and proper training for laboratory personnel to minimize the risk of laboratory-acquired infections.
1. Asbestosis: a lung disease caused by inhaling asbestos fibers.
2. Carpal tunnel syndrome: a nerve disorder caused by repetitive motion and pressure on the wrist.
3. Mesothelioma: a type of cancer caused by exposure to asbestos.
4. Pneumoconiosis: a lung disease caused by inhaling dust from mining or other heavy industries.
5. Repetitive strain injuries: injuries caused by repetitive motions, such as typing or using vibrating tools.
6. Skin conditions: such as skin irritation and dermatitis caused by exposure to chemicals or other substances in the workplace.
7. Hearing loss: caused by loud noises in the workplace.
8. Back injuries: caused by lifting, bending, or twisting.
9. Respiratory problems: such as asthma and other breathing difficulties caused by exposure to chemicals or dust in the workplace.
10. Cancer: caused by exposure to carcinogens such as radiation, certain chemicals, or heavy metals in the workplace.
Occupational diseases can be difficult to diagnose and treat, as they often develop gradually over time and may not be immediately attributed to the work environment. In some cases, these diseases may not appear until years after exposure has ended. It is important for workers to be aware of the potential health risks associated with their job and take steps to protect themselves, such as wearing protective gear, following safety protocols, and seeking regular medical check-ups. Employers also have a responsibility to provide a safe work environment and follow strict regulations to prevent the spread of occupational diseases.
Bohr effect
Bier spots
Leukocyte extravasation
Otto Frank (physiologist)
Patrouille de France
Sleep inertia
Staub-Traugott Phenomenon
Adult stem cell
Erythrocyte aggregation
Regeneration (biology)
Reflex syncope
Alexandria School of Medicine
Carbon dioxide
Transient hepatic attenuation differences
Patch-sequencing
Walter Myers (physician)
Heart rate variability
Joseph Lister
Misattribution of arousal
Taurine
Sir John Bradford, 1st Baronet
Maternal fetal stress transfer
Hypoxic pulmonary vasoconstriction
Lord's paradox
Ancel Keys
Cushing reflex
HPV (disambiguation)
Suspension trauma
Goose bumps
Maurício Rocha e Silva
Nonviolent video game
Hibernation
Carl Ludwig
Psychology of religion
Metabolism
Senescence
Zymoblot
Psychological stress and sleep
Listener fatigue
List of Puerto Rican scientists and inventors
Anger management
Synaptic fatigue
Factor XIII
Physiologically based pharmacokinetic modelling
Chronic cerebrospinal venous insufficiency controversy
Enzyme inhibitor
Roger Masters
Igor Kufayev
Find-me signals
Loop diuretic
Linear no-threshold model
Macropsia
Aequorin
Sexual coercion among animals
Heme
Alkaline phosphatase
Allometry
Effects of hormones on sexual motivation
Timeline of United States inventions (1890-1945)
Blood Physiological Phenomena - MeSH - NCBI
Subjects: Blood Physiological Phenomena - Digital Collections - National Library of Medicine Search Results
On the Periodicity of Cardiovascular Fluid Dynamics Simulations
Maternal energy stores and diet composition during pregnancy program adolescent blood pressure - PubMed
Publication Detail
Portal Regional da BVS
MeSH Browser
Pregnancy and Urolithiasis: Practice Essentials, Pathophysiology, Etiology
WHO EMRO | Prevalence and predictors of white-coat hypertension in a large database of ambulatory blood pressure monitoring |...
Vibration Syndrome (83-110) | NIOSH | CDC
DailyMed - AMPHETAMINE SULFATE tablet
DailyMed - AMPHETAMINE SULFATE tablet
RFA-HL-06-004: NHLBI Exploratory Program in Systems Biology (R33)
Advancing MRI Techniques to Understand Placental Functioning | NICHD - Eunice Kennedy Shriver National Institute of Child...
Crows possess higher intelligence long thought primarily human - STAT
Edith Hamel, PhD | The Neuro - McGill University
The Splintered Mind: Do Some People Literally See Red When They're Angry?
Frontiers | Interplay Between Optimal Ventilation and Gas Transport in a Model of the Human Lung
DeCS
MeSH Browser
Let's clear things up: how do glassfrogs achieve transparency?
ugt1a10 gene|ugt1a10 gene|C1421323|udp glucuronosyltransferase 1 family, polypeptide a10|gngm
AMINOCAPROIC ACID INJECTION, USP
Blood pressure variability: methodological aspects, clinical... : Journal of Hypertension
IMSEAR at SEARO: Search
Physiology2
- These projects will combine computational modeling and simulation approaches with experimental validation of model predictions to advance understanding the normal physiology and perturbations associated with heart, lung, blood, and sleep (HLBS) disorders. (nih.gov)
- This approach yields a more accurate, more robust measurement capability with improved bandwidth that allows new analytical approaches for assessing the physiology of skull expansion under pulsatile cerebral blood flow. (techbriefs.com)
Circulatory1
- In vertebrates like humans, tissue transparency is particularly difficult to achieve, as our circulatory systems are filled with oxygen-carrying red blood cells that strongly absorb light and render our tissues opaque," explained NIBIB-funded researcher Junjie Yao, Ph.D., an assistant professor of biomedical engineering at Duke University. (nih.gov)
Humans2
- Understanding this blood flow mechanism in the glassfrog may provide insights into disorders related to blood clotting or stroke in humans. (nih.gov)
- It offers the possibility for the monitoring of transcranial expansion and related physiological phenomena in humans resulting from variations in intracranial pressure (ICP) caused by injuries to the head and/or brain pathologies. (techbriefs.com)
Circulation5
- Hence, the control of ventilation is coupled to the control of heart rate, so that both lung ventilation and blood circulation are coordinated in order to cope with body needs. (frontiersin.org)
- The amount of power spent for ventilation comes from two main physical phenomena: the dissipation due to air circulation in the bronchi, related to the hydrodynamic resistance of the lung, and to the elastic power stored in lung's tissue. (frontiersin.org)
- Their findings, recently published on the cover of Science , demonstrate that glassfrogs can remove almost 90% of their red blood cells from circulation, storing them in the liver during rest. (nih.gov)
- This means that the glassfrog depletes its red blood cells from circulation during rest, allowing for enhanced tissue transparency and camouflage during this vulnerable time. (nih.gov)
- These fats are known to be bad cholesterol as they have a bad impact on cardiac health and blood circulation. (allhealthpost.com)
Physical phenomena1
- We propose a model for oxygen and carbon dioxide transport in the lung that accounts for the core physical phenomena: lung's tree-like geometry, transport of gas by convection and diffusion, exchanges with blood and a sinusoidal ventilation. (frontiersin.org)
Processes1
- Physiological processes and properties of the BLOOD. (nih.gov)
Narrower1
- Vasoconstriction is a physiological or induced process in which the blood vessels become narrower due to the contraction of the smooth muscles that line the walls of the vessels. (allhealthpost.com)
Vessels5
- Relying on splitting time schemes established for fluid-structure interaction to model blood vessels, we propose a semi-implicit discretization of a general poromechanics formulation, satisfying a discrete energy balance. (hal.science)
- Salty Food - The sodium present in salt can lead to water retention which will increase blood volume, thus constricting the blood vessels. (allhealthpost.com)
- Alcohol - Moderate and heavy consumption of alcohol can lead to thickening of the walls of the blood vessels and thus, cause vasoconstriction. (allhealthpost.com)
- Monosodium Glutamate - Commonly used as a flavor enhancer, MSG helps open up the calcium channels, thus causing constricting effect on the blood vessels. (allhealthpost.com)
- Medications - Since the blood vessels become narrow, medications that act as vasodilators can be used to increase the blood flow. (allhealthpost.com)
Hypertensive1
- Impeded blood flow within the placenta has been linked to pregnancy-related hypertensive disorders, including preeclampsia . (nih.gov)
Factors1
- Candidates did not accurately define V/Q inequality and the physiological factors causing this phenomenon. (derangedphysiology.com)
Characteristics3
- The transfer of these two species between lung and blood are driven by the amount of blood flow in pulmonary capillaries, the gradient of the partial pressure between alveoli and capillaries, the blood/alveoli membrane characteristics and the properties of the ventilation cycle. (frontiersin.org)
- Researchers supported by NICHD through the Human Placenta Project are using novel magnetic resonance imaging (MRI) techniques to study blood flow, oxygenation, and other physiological characteristics of the placenta-and their potential relationship to preeclampsia and other high-risk pregnancy conditions. (nih.gov)
- For two-year-old rats, low content of erythrocytes-disconcytes in the blood and an excess number of erythrocytes with a modified shape, as well as an increase in their aggregation, are characteristics. (jbiochemtech.com)
Venous1
- The lower the V/Q ratio, the closer the effluent blood composition gets to mixed venous blood, i.e. to "true" shunt. (derangedphysiology.com)
Mechanisms3
- However, the physiological mechanisms regulating placental blood flow are not well understood. (nih.gov)
- Researchers said this is an important discovery that provides a better understanding of the physiological mechanisms necessary for maintaining optimal blood and oxygen exchange levels between the mother and fetus. (nih.gov)
- In our study, we have discovered that the glassfrog can conceal nearly all of its red blood cells within its liver on a daily basis, resulting in a unique form of camouflage that is distinct from all other known mechanisms of tissue transparency. (nih.gov)
Protein2
- To understand the mechanism of this transparency, the researchers first used spectroscopy techniques to passively measure glassfrog's levels of hemoglobin (a protein in red blood cells that carries oxygen and absorbs light). (nih.gov)
- This method has been demonstrated to induce the rapid binding of albumin from single and binary protein solutions, from plasma, and apparently, from whole blood. (tamu.edu)
Systolic2
- Peripheral actions include elevations of systolic and diastolic blood pressures, and weak bronchodilator, and respiratory stimulant action. (nih.gov)
- Short/branched chain acyl-CoA dehydrogenase and Sah also showed a significant association with systolic blood pressure. (bvsalud.org)
Pump2
- From there, diffusion occurs downward the bronchial tree for oxygen, as blood acts as an oxygen pump, and upward the bronchial tree for carbon dioxide, as blood acts as a carbon dioxide source. (frontiersin.org)
- The same research team also identified a new physiological phenomenon, the "utero-placental pump," by which the placenta and underlying uterine wall contract independently of the rest of the uterus to expel maternal blood. (nih.gov)
Pressure19
- Regulation is performed through inputs from sensors, amongst which sensors to oxygen and carbon dioxide partial pressure in blood play a crucial role. (frontiersin.org)
- As a consequence, partial pressure in oxygen and carbon dioxide in blood are strongly regulated in mammals ( Weibel, 1984 ). (frontiersin.org)
- The control of ventilation is based on the regulation of the volume of air that is internalized (ventilation amplitude) and the frequency at which this volume of air is renewed (ventilation frequency) with the aim to keep oxygen and carbon dioxide partial pressure constant in blood. (frontiersin.org)
- Some medical conditions, particularly fractures, lacerations, costoclavicular syndrome, connective tissue diseases, vascular disorders such as Buerger's disease, generalized atherosclerosis, or a long history of high blood pressure, may result in the same signs and symptoms as primary Raynaud's phenomenon. (cdc.gov)
- A total of 2462 patients underwent ambulatory blood pressure monitoring either in borderline hypertension (group 1) or for assessment of antihypertensive treatment (group 2) or for hypotension (group 3). (who.int)
- WCE is defined as the transient rise in blood pressure (BP) from before to during the clinic visit, whereas WCH (also referred to as "office hypertension" or "isolated clinical hypertension") is generally defined as persistently elevated office BP in the presence of a normal BP outside the office, regardless of the extent of the WCE [1]. (who.int)
- The condition can lead to poor regulation of blood pressure in the pregnant person. (nih.gov)
- This method monitors transcranial expansion and related physiological phenomena resulting from variations in intracranial pressure (ICP). (techbriefs.com)
- Several studies have suggested that this enzyme may play a role in blood pressure regulation. (bvsalud.org)
- A genome-wide quantitative trait loci (QTL) analysis of blood pressure using 107 F2 rats indicated that a statistically significant QTL for pulse pressure was located at the Comt locus in chromosome 11. (bvsalud.org)
- However, COMT inhibitors had no significant effects on blood pressure in either DS or LEW rats. (bvsalud.org)
- In a previous study, we performed a genome-wide quantitative trait loci (QTLs) analysis for blood pressure using F2 rats derived from Dahl salt-sensitive (DS) and Lewis (LEW) rats and identified two QTLs that influenced blood pressure levels. (bvsalud.org)
- The purpose of the present study was to identify candidate genes that influence blood pressure in the Ch10 QTL region. (bvsalud.org)
- Intriguingly, this Ch10 QTL for blood pressure was also a possible QTL for urinary albumin excretion. (bvsalud.org)
- We obtained 101 F2 male rats from Dahl-S and Lewis rats and performed precise measurements of blood pressure (BP) and heart rate by telemetric monitoring at 14 weeks of age after 9 weeks of salt-loading. (bvsalud.org)
- Blood Pressure. (oap-journals.org)
- Heart rate, blood pressure, gastrointestinal motility, galvanic skin response, and biochemical indicators were measured as physiological responses, and affective and semantic rating scales were used as subjective responses. (cdc.gov)
- Licorice - The extract of licorice root that's often used in alcoholic drinks, candy, tea, etc. contains a compound called glycyrrhizin acid which causes potassium loss and sodium retention in the body that increases blood pressure. (allhealthpost.com)
- Describe the effects of V/Q inequality on the partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2) in arterial blood. (derangedphysiology.com)
Carbon dioxide2
- While oxygen directly affects the cells' access to energy, carbon dioxide drives blood pH, whose allowed range for healthy cellular function is tight ( Madshus, 1988 ). (frontiersin.org)
- In order for ventilation to handle blood homeostasy, it has to drag from blood a sufficient amount of carbon dioxide and to feed blood with sufficient amounts of oxygen. (frontiersin.org)
Injuries1
- This physiological phenomenon is quite important in preventing blood loss during injuries, hemorrhages, etc. and also helps in heat preservation. (allhealthpost.com)
Albumin1
- Influence of endogenous albumin binding on blood-material interactions. (tamu.edu)
Important1
- It is important to remember that this is a physiological response - it doesn't mean you want to have sex with the gym! (refinery29.com)
Oxygen3
- Proper blood flow is essential for ensuring the fetus receives sufficient oxygen and nutrients during development. (nih.gov)
- By contrast, in pregnant women with preeclampsia, researchers observed faster rates of blood flow and lower and more variable oxygen rates across the placenta compared with the healthy pregnancy group. (nih.gov)
- Providing new insights into placental blood flow, oxygen transport, and how the placenta and uterus contract independently can help researchers develop new clinical tests to identify at-risk pregnancies. (nih.gov)
Peripheral1
- Since IFN-γ and T-bet can be detected in peripheral blood of AA patients, it was believed autoreactive T lymphocytes were invovled in destroying the hematopoietic stem cells (HSCs) in the bone marrow (BM). (nih.gov)
Insights1
- Our model is able to predict physiological ventilation properties and brings interesting insights on the robustness of different regimes. (frontiersin.org)
Flow11
- Preeclampsia has been linked to poor blood vessel development and blood flow within the placenta. (nih.gov)
- To better understand blood flow and oxygenation patterns within the placenta, researchers from the Sir Peter Mansfield Imaging Centre in Nottingham, United Kingdom, used phase contrast angiography (PCA) and diffusion-weighted imaging (DWI) MRI techniques to compare these patterns in women with healthy pregnancies and in women with preeclampsia. (nih.gov)
- In one study , researchers found that in healthy pregnancies, blood flow speed decreased from the uterine wall through to the placenta. (nih.gov)
- Caption: Map of the net speed of blood flow in the placenta at the level of the MRI voxels. (nih.gov)
- Additional research is needed to investigate the links between oxygenation and blood flow during contractions and identify what triggers these contractions. (nih.gov)
- Photoacoustic microscopy allowed us to capture the blood flow dynamics of the glassfrogs, even though those changes occur deep inside their opaque internal organs," explained Carlos Taboada, Ph.D., a postdoctoral associate at Duke University and one of the leading authors of this study. (nih.gov)
- Traditional imaging methods can't track blood flow with such a high level of accuracy or tell us exactly where the glassfrogs are storing their red blood cells. (nih.gov)
- Grace agrees and adds that people may also be experiencing physiological arousal that builds during exercise, like increased blood flow and a quickening heart rate. (refinery29.com)
- This mainly occurs in the small arterioles as well as large arteries and reduces the blood flow to different parts of the body. (allhealthpost.com)
- Vasoconstriction impedes regular blood flow that not only affects the overall health of an individual, but can also have an impact on cardiac health, leading to fatality in the long term. (allhealthpost.com)
- The inability of high V/Q areas to compensate for low V/Q zones owing to the relatively small contribution of blood flow from these high V/Q units was not discussed. (derangedphysiology.com)
Affects1
- The progression of aging affects various blood parameters, which can weaken the viability of the body. (jbiochemtech.com)
Cardiac1
- Baroreflex Sensitivity, Cardiac and Kidney Remodeling and Deterioration in Vasoactive Substances Content in Blood in Experimental Model of Renovascular Hypertension. (oap-journals.org)
Lung1
- The National Heart, Lung, and Blood Institute (NHLBI) invites applications for collaborative research projects to initiate high-risk, high impact research by multidisciplinary teams of investigators. (nih.gov)
Authors1
- The authors conclude that physiological responses to sound bear uncertain relationships to subjective aversive/nonaversive judgements. (cdc.gov)
Excess1
- This was accompanied in them by an excess content of erythrocytes in the blood, which had a changed shape to varying degrees. (jbiochemtech.com)
Response1
- Sickness behavior is a physiological behavioral response principally induced and regulated by proinflammatory cytokines, including interleukin 1β (IL-1β), IL-6 and tumor necrosis factor (TNF)α, which act centrally to induce sickness behaviors, including pyrexia. (biomedcentral.com)
Retention1
- Long-term catheter implant studies suggest that the C18 alkylation is more effective than most, if not all, currently available treatments for the retention of a clean, biocompatible, blood-contacting surface. (tamu.edu)
Condition2
- In light of a recently completed, comprehensive study, conducted by the National Institute for Occupational Safety and Health (NIOSH), the Institute concludes that vibrating hand tools can cause vibration syndrome, a condition also known as vibration white finger and as Raynaud's phenomenon of occupational origin. (cdc.gov)
- We have observed AA-like symptoms in our IFN-γ AU-rich element (ARE) - deleted (del) mice which constitutively express low level of IFN-γ under physiological condition. (nih.gov)
Occurs2
- Cases tend to be underreported by physicians because most have not been informed of how to distinguish the symptoms of Raynaud's phenomenon from other medical conditions where blanching or sensory loss occurs. (cdc.gov)
- Primary" Raynaud's phenomenon, originally described by Dr. Maurice Raynaud, occurs spontaneously in less than 15% of the general population. (cdc.gov)
Model1
- The model derived illustrates physiological phenomena inaccessible in former models, and with great clinical application potential, such as vasodilatation and coronary diseases.The integration of a porous compartment to represent the perfused myocardium within 3D models is more challenging. (hal.science)
Rats3
- The examined 24-month-old rats showed standard aging phenomena. (jbiochemtech.com)
- In the blood of two-year-old rats, there was a decrease in the level of erythrocyte-discocytes. (jbiochemtech.com)
- In rats of the older group, erythrocyte aggregation was increased, as indicated by an increase in the numberof erythrocytes that entered the aggregates in the blood and an increase in the number of most erythrocyte aggregates with a decrease in the level of free erythrocytes. (jbiochemtech.com)
Results1
- These results are fully coherent with the physiological observation and raises the question: how the control of ventilation could select for the optimal configuration? (frontiersin.org)
Level4
- This page refers to a blood lead level of 5 micrograms per deciliter (μg/dL) as the CDC's blood lead reference value. (cdc.gov)
- This new level is based on the U.S. population of children ages 1-5 years who represent the top 2.5% of children with the highest blood lead levels. (cdc.gov)
- Specify that there is no identified threshold or safe level of lead in blood. (cdc.gov)
- There is no identified threshold or safe level of lead in blood" [AAP 2016]. (cdc.gov)
Levels1
- As of October 28, 2021, CDC uses a blood lead reference value of 3.5 micrograms per deciliter to identify children with blood lead levels that are higher than most children's levels. (cdc.gov)
Research1
- Grace shares that there isn't any conclusive research about why coregasms happen, though research from 2021 found that 9% of surveyed participants admitted to experiencing this phenomenon. (refinery29.com)
Type1
- Nous inspirant des schémas en temps de type splitting établis en interaction fluide-structure pour modéliser les vaisseaux sanguins, nous proposons une discrétisation semi-implicite d'une formulation générale de poromécanique, satisfaisant un bilan d'énergie au niveau discret. (hal.science)