Blood Loss, Surgical: Loss of blood during a surgical procedure.Hemostasis, Surgical: Control of bleeding during or after surgery.Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.Postoperative Hemorrhage: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.Antifibrinolytic Agents: Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.Blood Transfusion: The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Hemostatics: Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.Postpartum Hemorrhage: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).Tourniquets: Devices for the compression of a blood vessel by application around an extremity to control the circulation and prevent the flow of blood to or from the distal area. (From Dorland, 28th ed)Operative Time: The duration of a surgical procedure in hours and minutes.Blood Transfusion, Autologous: Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)Hemorrhage: Bleeding or escape of blood from a vessel.Aprotinin: A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Menorrhagia: Excessive uterine bleeding during MENSTRUATION.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Melena: The black, tarry, foul-smelling FECES that contain degraded blood.Surgical Procedures, Minimally Invasive: Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Oxytocics: Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)Labor Stage, Third: The final period of OBSTETRIC LABOR that is from the expulsion of the FETUS to the expulsion of the PLACENTA.Robotics: The application of electronic, computerized control systems to mechanical devices designed to perform human functions. Formerly restricted to industry, but nowadays applied to artificial organs controlled by bionic (bioelectronic) devices, like automated insulin pumps and other prostheses.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Thrombelastography: Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.Arthroplasty, Replacement, Knee: Replacement of the knee joint.Electrocoagulation: Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.Spinal Fusion: Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Hemodilution: Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.Intraoperative Period: The period during a surgical operation.Erythrocyte Transfusion: The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Fibrin Tissue Adhesive: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.Hypotension, Controlled: Procedure in which arterial blood pressure is intentionally reduced in order to control blood loss during surgery. This procedure is performed either pharmacologically or by pre-surgical removal of blood.Retroperitoneal Space: An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.Perioperative Care: Interventions to provide care prior to, during, and immediately after surgery.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Hysterectomy: Excision of the uterus.Nephrectomy: Excision of kidney.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Blood Volume Determination: Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.Operative Blood Salvage: Recovery of blood lost from surgical procedures for reuse by the same patient in AUTOLOGOUS BLOOD TRANSFUSIONS. It is collected during (intraoperatively) or after completion of (postoperatively) the surgical procedures.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Compression Bandages: Strips of elastic material used to apply pressure to body parts to control EDEMA and aid circulation.Shock, Hemorrhagic: Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Arthroplasty, Replacement, Hip: Replacement of the hip joint.Gynecologic Surgical Procedures: Surgery performed on the female genitalia.Hemostasis: The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.Hysterectomy, Vaginal: Removal of the uterus through the vagina.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Scoliosis: An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)Hemostatic Techniques: Techniques for controlling bleeding.Plasma Substitutes: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.Perioperative Period: The time periods immediately before, during and following a surgical operation.Hydroxyethyl Starch Derivatives: Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.Iron Isotopes: Stable iron atoms that have the same atomic number as the element iron, but differ in atomic weight. Fe-54, 57, and 58 are stable iron isotopes.Anemia, Hypochromic: Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393)Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Postgastrectomy Syndromes: Sequelae of gastrectomy from the second week after operation on. Include recurrent or anastomotic ulcer, postprandial syndromes (DUMPING SYNDROME and late postprandial hypoglycemia), disordered bowel action, and nutritional deficiencies.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Menstrual Hygiene Products: Personal care items used during MENSTRUATION.Bone Screws: Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.Occult Blood: Chemical, spectroscopic, or microscopic detection of extremely small amounts of blood.Central Venous Pressure: The blood pressure in the central large VEINS of the body. It is distinguished from peripheral venous pressure which occurs in an extremity.Necator: A genus of intestinal parasite worms which includes one of the most important hookworms of man, NECATOR AMERICANUS. The only other known species, N. suillus, has been recovered from pigs.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Myoma: A benign neoplasm of muscular tissue. (Stedman, 25th ed)Leiomyoma: A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Uterine Hemorrhage: Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.Sacrum: Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.Blood Coagulation: The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Constriction: The act of constricting.Pancreaticoduodenectomy: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.Learning Curve: The course of learning of an individual or a group. It is a measure of performance plotted over time.Laparoscopes: ENDOSCOPES for examining the abdominal and pelvic organs in the peritoneal cavity.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Suture Techniques: Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).Misoprostol: A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties.Surgical Procedures, Elective: Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.Phlebotomy: The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Internal Fixators: Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.Menstruation: The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.Uterine Neoplasms: Tumors or cancer of the UTERUS.Lumbar Vertebrae: VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.Fluid Therapy: Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.Hand-Assisted Laparoscopy: Placement of one of the surgeon's gloved hands into the ABDOMINAL CAVITY to perform manual manipulations that facilitate the laparoscopic procedures.Prostatectomy: Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).Angiodysplasia: Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.Chromium Isotopes: Stable chromium atoms that have the same atomic number as the element chromium, but differ in atomic weight. Cr-50, 53, and 54 are stable chromium isotopes.Thoracic Surgery, Video-Assisted: Endoscopic surgery of the pleural cavity performed with visualization via video transmission.Spinal NeoplasmsOrthopedic Procedures: Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Factor VIIa: Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.Laparotomy: Incision into the side of the abdomen between the ribs and pelvis.Gastrectomy: Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)Bleeding Time: Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.Thoracic Vertebrae: A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.Fracture Fixation, Internal: The use of internal devices (metal plates, nails, rods, etc.) to hold the position of a fracture in proper alignment.Urologic Surgical Procedures: Surgery performed on the urinary tract or its parts in the male or female. For surgery of the male genitalia, UROLOGIC SURGICAL PROCEDURES, MALE is available.Bone Nails: Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Isotonic Solutions: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Surgical Procedures, Operative: Operations carried out for the correction of deformities and defects, repair of injuries, and diagnosis and cure of certain diseases. (Taber, 18th ed.)Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Gelatin Sponge, Absorbable: Sterile, gelatin-base surgical sponge applied topically as an adjunct to hemostasis when the control of bleeding by conventional procedures is ineffective to reduce capillary ooze or is impractical. (From AMA Drug Evaluations Annual, 1994, p797)Postoperative Period: The period following a surgical operation.Whole Blood Coagulation Time: The time required by whole blood to produce a visible clot.Pain, Postoperative: Pain during the period after surgery.Jehovah's Witnesses: Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.Kyphosis: Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.Umbilicus: The pit in the center of the ABDOMINAL WALL marking the point where the UMBILICAL CORD entered in the FETUS.Spine: The spinal or vertebral column.Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Ancylostoma: A genus of nematode intestinal parasites that consists of several species. A. duodenale is the common hookworm in humans. A. braziliense, A. ceylonicum, and A. caninum occur primarily in cats and dogs, but all have been known to occur in humans.Deamino Arginine Vasopressin: A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.Prothrombin Time: Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.Surgery, Computer-Assisted: Surgical procedures conducted with the aid of computers. This is most frequently used in orthopedic and laparoscopic surgery for implant placement and instrument guidance. Image-guided surgery interactively combines prior CT scans or MRI images with real-time video.Digestive System Surgical Procedures: Surgery performed on the digestive system or its parts.Platelet Transfusion: The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.Embolization, Therapeutic: A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.Sutures: Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)Polyvinyl Alcohol: A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.Uterine Myomectomy: Surgical removal of a LEIOMYOMA of the UTERUS.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Uterine Inertia: Failure of the UTERUS to contract with normal strength, duration, and intervals during childbirth (LABOR, OBSTETRIC). It is also called uterine atony.Decompression, Surgical: A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)Partial Thromboplastin Time: The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Patient Positioning: Moving a patient into a specific position or POSTURE to facilitate examination, surgery, or for therapeutic purposes.Shock, Surgical: A type of shock that occurs as a result of a surgical procedure.Living Donors: Non-cadaveric providers of organs for transplant to related or non-related recipients.Anesthesia, General: Procedure in which patients are induced into an unconscious state through use of various medications so that they do not feel pain during surgery.Cardiac Surgical Procedures: Surgery performed on the heart.Ethamsylate: Benzenesulfonate derivative used as a systemic hemostatic.Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Surgical Stapling: A technique of closing incisions and wounds, or of joining and connecting tissues, in which staples are used as sutures.Conversion to Open Surgery: Changing an operative procedure from an endoscopic surgical procedure to an open approach during the INTRAOPERATIVE PERIOD.Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.Hemoglobinometry: Measurement of hemoglobin concentration in blood.Erythrocyte Volume: Volume of circulating ERYTHROCYTES . It is usually measured by RADIOISOTOPE DILUTION TECHNIQUE.Anemia, Iron-Deficiency: Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.Vital Signs: The signs of life that may be monitored or measured, namely pulse rate, respiratory rate, body temperature, and blood pressure.Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Tissue and Organ Harvesting: The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.Thoracoscopy: Endoscopic examination, therapy or surgery of the pleural cavity.Surgical Staplers: Fastening devices composed of steel-tantalum alloys used to close operative wounds, especially of the skin, which minimizes infection by not introducing a foreign body that would connect external and internal regions of the body. (From Segen, Current Med Talk, 1995)Blood Coagulation Factors: Endogenous substances, usually proteins, that are involved in the blood coagulation process.Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Cautery: The application of a caustic substance, a hot instrument, an electric current, or other agent to control bleeding while removing or destroying tissue.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Liver Neoplasms: Tumors or cancer of the LIVER.Infusions, Intralesional: The administration of medication or fluid directly into localized lesions, by means of gravity flow or INFUSION PUMPS.Diskectomy: Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.Surgical Equipment: Nonexpendable apparatus used during surgical procedures. They are differentiated from SURGICAL INSTRUMENTS, usually hand-held and used in the immediate operative field.Bone Cements: Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.Ureter: One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER.Kidney Neoplasms: Tumors or cancers of the KIDNEY.Femoral Fractures: Fractures of the femur.Anastomotic Leak: Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).Lymph Node Excision: Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)Perineum: The body region lying between the genital area and the ANUS on the surface of the trunk, and to the shallow compartment lying deep to this area that is inferior to the PELVIC DIAPHRAGM. The surface area is between the VULVA and the anus in the female, and between the SCROTUM and the anus in the male.Fracture Fixation, Intramedullary: The use of nails that are inserted into bone cavities in order to keep fractured bones together.Arthroplasty, Replacement, Elbow: Replacement of the ELBOW JOINT.Blood Component Transfusion: The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.Labor Stage, Second: The period of OBSTETRIC LABOR that is from the complete dilatation of the CERVIX UTERI to the expulsion of the FETUS.Delivery, Obstetric: Delivery of the FETUS and PLACENTA under the care of an obstetrician or a health worker. Obstetric deliveries may involve physical, psychological, medical, or surgical interventions.Esophagectomy: Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Pelvic Bones: Bones that constitute each half of the pelvic girdle in VERTEBRATES, formed by fusion of the ILIUM; ISCHIUM; and PUBIC BONE.Hypovolemia: An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Equipment Design: Methods of creating machines and devices.Single-Blind Method: A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.Platelet-Rich Plasma: A preparation consisting of PLATELETS concentrated in a limited volume of PLASMA. This is used in various surgical tissue regeneration procedures where the GROWTH FACTORS in the platelets enhance wound healing and regeneration.Aortic Rupture: The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.Uterine Diseases: Pathological processes involving any part of the UTERUS.Osteotomy, Le Fort: Transverse sectioning and repositioning of the maxilla. There are three types: Le Fort I osteotomy for maxillary advancement or the treatment of maxillary fractures; Le Fort II osteotomy for the treatment of maxillary fractures; Le Fort III osteotomy for the treatment of maxillary fractures with fracture of one or more facial bones. Le Fort III is often used also to correct craniofacial dysostosis and related facial abnormalities. (From Dorland, 28th ed, p1203 & p662)Fibrinolysis: The natural enzymatic dissolution of FIBRIN.Monitoring, Intraoperative: The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).Osteotomy: The surgical cutting of a bone. (Dorland, 28th ed)Bloodless Medical and Surgical Procedures: The treatment of patients without the use of allogeneic BLOOD TRANSFUSIONS or blood products.Laminectomy: A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.Blood Grouping and Crossmatching: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.

Use of high-intensity focused ultrasound to control bleeding. (1/1113)

OBJECTIVE: High-intensity focused ultrasound (HIFU) has been shown to be effective in controlling hemorrhage from punctures in blood vessels. The objective of the current study was to investigate the capability of HIFU to stop bleeding after a more severe type of vascular injury, namely longitudinal incisions of arteries and veins. METHODS: The superficial femoral arteries, common femoral arteries, carotid arteries, and jugular veins of four anesthetized pigs were exposed surgically. A longitudinal incision, 2 to 8 mm in length, was produced in the vessel. HIFU treatment was applied within 5 seconds of the onset of the bleeding. The HIFU probe consisted of a high-power, 3.5-MHz, piezoelectric transducer with an ellipsoidal focal spot that was 1 mm in cross section and 9 mm in axial dimension. The entire incision area was scanned with the HIFU beam at a rate of 15 to 25 times/second and a linear displacement of 5 to 10 mm. A total of 76 incisions and HIFU treatments were performed. RESULTS: Control of bleeding (major hemosatsis) was achieved in all 76 treatments, with complete hemostasis achieved in 69 treatments (91%). The average treatment times of major and complete hemostasis were 17 and 25 seconds, respectively. After the treatment, 74% of the vessels in which complete hemostasis was achieved were patent with distal blood flow and 26% were occluded. The HIFU-treated vessels showed a consistent coagulation of the adventitia surrounding the vessels, with a remarkably localized injury to the vessel wall. Extensive fibrin deposition at the treatment site was observed. CONCLUSION: HIFU may provide a useful method of achieving hemostasis for arteries and veins in a variety of clinical applications.  (+info)

Prolonged continuous or intermittent vascular inflow occlusion during hemihepatectomy in pigs. (2/1113)

OBJECTIVE: To assess ischemia and reperfusion (I/R) injury in a hemihepatectomy model in pigs after prolonged continuous or intermittent vascular inflow occlusion in the liver. SUMMARY BACKGROUND DATA: Massive intraoperative blood loss during liver resections can be prevented by temporary vascular inflow occlusion, consequently leading to ischemia and reperfusion injury in the remnant liver. Previously, in a pig liver resection model in which only limited I/R injury was induced during brief (90 min) vascular inflow occlusion, the authors demonstrated reduced I/R injury after continuous (CNT) occlusion, compared to intermittent (INT). This liver resection study on pigs was undertaken to assess I/R injury after prolonged (120 min) CNT or INT occlusion. METHODS: In pigs (37.0 +/- 1.5 kg), liver ischemia during 2 hours was CNT (n = 6) or INT (n = 6) (eight subsequent periods of 12 min ischemia and 3 min recirculation), followed by 6 hours of reperfusion. A left hemihepatectomy (45.5% +/- 1.4%) was performed within the first 12 minutes of ischemia. No hepatic pedicle clamping or liver resection was performed in control experiments (n = 6). Microvascular damage was assessed by hyaluronic acid (HA) uptake capacity of the liver (parameter of early sinusoidal endothelial cell damage) and restoration of intrahepatic tissue pO2 during reperfusion. Hepatocellular damage was tested by plasma concentrations of aspartate aminotransferase (AST), alanine aminotransferase, and lactate dehydrogenase (LDH). RESULTS: Hyaluronic acid uptake after 6 hours of reperfusion, compared to preischemic uptake, was unaltered in the control group, but was significantly reduced in both resection groups. However, more HA was taken up after INT occlusion, compared to CNT (60.4% +/- 5.6% and 39.5% +/- 3.7%, respectively; ANOVA: p = 0.001). Intrahepatic tissue pO2 distribution after 6 hours of reperfusion more closely returned to preischemic configuration in the INT group than in the CNT group, indicating reduced microcirculatory disturbances after INT occlusion. Release of AST and LDH after 6 hours of reperfusion was significantly increased in both CNT and INT groups. Lower AST levels, however, were found after INT occlusion than after CNT occlusion (267.0 +/- 74.7 U/l and 603.3 +/- 132.4 U/l, respectively; p = 0.06). CONCLUSIONS: Intermittent hepatic vascular inflow occlusion during prolonged liver ischemia in pigs resulted in less microcirculatory and hepatocellular injury, compared to continuous occlusion. Intermittent clamping is preferable when prolonged periods of vascular inflow occlusion are applied during liver resections.  (+info)

Simultaneous bilateral total knee arthroplasty in a single procedure. (3/1113)

Eighty-eight consecutive patients undergoing total knee arthroplasty (TKA) were reviewed retrospectively and divided into two groups. Group I (64 patients) had both knees replaced simultaneously by one team in a single procedure while Group II (24 patients) had 2 operations staged about 7 days apart. The blood loss, operative time, knee functional score, period of hospitalisation and complications were documented in order to compare the 2 groups. Performing simultaneous bilateral TKA (Group I) did not increase the incidence of operative or post-operative complications. Equally, the functional score and mean intra- and post-operative blood loss were not influenced. The operative time and duration of hospitalisation were significantly shorter in Group I than in Group II. On the basis of the results of this study, it appears that simultaneous bilateral TKA is beneficial.  (+info)

Non-invasive aortic blood flow measurement in infants during repair of craniosynostosis. (4/1113)

We have assessed the potential clinical benefit of a new echo-Doppler device (Dynemo 3000) which provides a continuous measure of aortic blood flow (ABF) using an aortic flowmeter and a paediatric oesophageal probe, during repair of craniosynostosis in infants under general anaesthesia. The data recorded included: ABFi (i = indexed to body surface area), stroke volume (SVi), systemic vascular resistance (TSVRi), pre-ejection period (PEP), left ventricular ejection time (LVET), mean arterial pressure (MAP), heart rate (HR) and central venous pressure (CVP). Data were collected: before (T1) and 3 min after skin incision (T2), at the time of maximal haemorrhage (T3) and at the end of the procedure (T4). Twelve infants (aged 7.0 (range 6-12) months) were included. ABFi, MAP and CVP were significantly lower at T3 compared with T1 (2.0 (0.8) vs 3.0 (0.8) litre min-1 m-2, 46.1 (5.8) vs 65.2 (8.9) mm Hg and 2.8 (1.6) vs 5.2 (2.1) mm Hg; P < 0.05). PEP/LVET ratio was significantly lower at T2 compared with T1 (0.25 (0.05) vs 0.30 (0.06)) and increased at T4 (0.36 (0.04); P < 0.05). These preliminary results suggest that this non-invasive ABF echo-Doppler device may be useful for continuous haemodynamic monitoring during a surgical procedure associated with haemorrhage in infants.  (+info)

Effect of infiltration with ropivacaine on blood loss during reduction mammoplasty. (5/1113)

Ropivacaine is a new aminoamide local anaesthetic agent. Unlike other agents in its class, such as bupivacaine, it has been found to be vasoconstrictive. We have sought to investigate if this property is clinically useful and may reduce surgical blood loss. Reduction mammoplasty is a procedure in which considerable blood loss may occur. We have compared pre-incision infiltration of ropivacaine 75 mg in 0.9% saline 60 ml with the current practice of infiltration with bupivacaine 75 mg in 0.9% saline 60 ml and epinephrine (adrenaline) 5 micrograms ml-1. We studied five subjects; each received both solutions by infiltration, one to each breast, in random order and both the operating surgeon and anaesthetist were blind to the solution given. For data analysis, blood loss was expressed in ml/kg of tissue excised. There was no significant difference between the two regimens for duration of surgery or amount of tissue excised; however, ropivacaine was associated with markedly greater intraoperative blood loss than bupivacaine (median 696 (range 305-1366) ml kg-1 vs 300 (169-608) ml kg-1; P = 0.04, Wilcoxon rank sum test). Postoperative blood loss was not significantly different between groups (116 (14-173) ml kg-1 vs 98 (13-332) ml kg-1; P = 0.69, Wilcoxon rank sum test). We conclude that the vasoconstrictive properties of ropivacaine were not sufficiently great to merit its use as a sole agent for infiltration before reduction mammoplasty.  (+info)

Randomised controlled trial of effect of terbutaline before elective caesarean section on postnatal respiration and glucose homeostasis. (6/1113)

AIM: To determine if terbutaline given to mothers before elective caesarean section facilitates neonatal respiration and metabolism. METHODS: A randomised controlled trial of 25 full term infants delivered by elective caesarean section was conducted. The mothers received a continuous infusion of terbutaline or saline 120-0 minutes before birth. Umbilical artery blood was collected at birth and analysed for blood gases and catecholamines. The lung function of each infant was assessed two hours after birth, and blood pressure, heart rate, blood glucose and body temperature were monitored until 24 hours of age. RESULTS: The infants of the treated mothers (n = 13) had significantly higher dynamic lung compliance (p < 0.001), lower airway resistance (p < 0.001), and respiratory frequency than control infants (n = 12). Blood glucose and adrenaline concentrations were significantly higher in the treated group (p = 0.0014 and p < 0.01). None of these infants had any clinical respiratory difficulties; there were two cases of transient tachypnoea in the control group. No negative side effects due to the terbutaline treatment were seen among the infants. The mothers felt no discomfort caused by the terbutaline infusion, although they bled more during surgery (p = 0.03). CONCLUSION: Stimulation of the beta adrenoceptors in utero with terbutaline infusion to the mothers promotes neonatal respiratory and metabolic adaptation after elective caesarean section.  (+info)

Haemodynamic assessment of hypovolaemia under general anaesthesia in pigs submitted to graded haemorrhage and retransfusion. (7/1113)

We have compared the value of different variables used in the assessment of blood loss during progressive hypovolaemia and resuscitation under general anaesthesia in anaesthetized pigs. We measured mean arterial pressure (MAP), pulmonary capillary wedge pressure (PCWP), the negative component of the systolic arterial pressure variation (delta Down) and left ventricular end-diastolic area (LVEDa) using echocardiography. Blood was progressively withdrawn (up to 35 ml kg-1 in seven steps) and then reinfused after the same pattern. Regression coefficient (r) and normalized slope (nS) of the regression relationship between each variable and amount of blood loss were determined. The difference between the withdrawal and reinfusion curves was assessed by the area between the curves. We also estimated the minimal loss of blood volume which induced significant changes in each variable compared with that under control conditions during withdrawal of blood (minWBV) and maximal loss in blood volume which induced no significant changes in a variable compared with control conditions during retransfusion (maxRBV). During haemorrhage, MAP decreased (from mean 74 (SD 9) to 31 (5) mm Hg; P < 0.001), delta Down increased (from 1.2 (1.4) to 11.4 (4.2) mm Hg; P < 0.001), PCWP decreased (from 6.2 (2.1) to 0.3 (1.0) mm Hg; P < 0.001) and LVEDa decreased (from 13.8 (2.0) to 5.1 (2.0) cm2; P < 0.01). The highest r values were obtained with MAP and LVEDa, and the highest nS value with delta Down. The least difference between withdrawal and reinfusion was with LVEDa, the lowest values of minWBV were with PCWP and LVEDa, and the highest value of maxRBV was obtained with PCWP. During progressive haemorrhage under general anaesthesia, LVEDa was an accurate variable for assessment of blood volume loss, delta Down contributed no further information compared with MAP, and PCWP was the most reliable variable for assessing return to baseline blood volume.  (+info)

Do obese patients bleed more? A prospective study of blood loss at total hip replacement. (8/1113)

This study compares blood loss at total hip replacement in obese and non-obese patients. We made a prospective study of intra-operative and postoperative blood loss in 80 consecutive primary cemented hip replacements. Patients' obesity was classified according to body mass index (BMI). Overall mean total blood loss was 1050 ml. Obese patients (BMI > 30) bled significantly more (P < 0.0001) than those of optimal weight (BMI < 26), whereas those overweight (BMI 26-30) did not. The mean excess blood loss in obese patients was 380 ml (95% confidence interval, 200-560 ml). At a time when the prevalence of obesity is increasing, this study quantifies the risks of greater blood loss with respect to obesity and aids informed consent.  (+info)

*Corpus callosotomy

Endoscopic corpus callosotomy has been employed with blood loss minimized during the surgical procedure. Corpus callosotomy is ... Improvements to surgical techniques, along with refinements of the indications, have allowed van Wagenen's procedure to endure ... Corpus callosotomy is a palliative surgical procedure for the treatment of medically refractory epilepsy. In this procedure the ... The most prominent non-surgical complications of corpus callosotomy relate to speech irregularities. For some patients, ...

*Tranexamic acid

... meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss". The British Journal of Surgery. 100 ... In surgical corrections of craniosynostosis in children it reduces the need for blood transfusions. In spinal surgery (e.g., ... It is of proven value in clearing the field of surgery and reducing blood loss when given before or after surgery. Drain and ... Tranexamic acid is used for a short period of time before and after the surgery to prevent major blood loss and decrease the ...

*Factor XI

There is little spontaneous bleeding, but surgical procedures may cause excessive blood loss, and prophylaxis is required. Low ... Emsley J, McEwan PA, Gailani D (Apr 2010). "Structure and function of factor XI". Blood. 115 (13): 2569-77. doi:10.1182/blood- ... Blood. 79 (6): 1435-40. PMID 1547342. Gailani D, Broze GJ (Aug 1991). "Factor XI activation in a revised model of blood ... Fujikawa K, Chung DW, Hendrickson LE, Davie EW (May 1986). "Amino acid sequence of human factor XI, a blood coagulation factor ...

*Ischemia-reperfusion injury of the appendicular musculoskeletal system

Aside from lower blood loss in itself, this improves visualization and surgical efficiency. Modern examples are found in many ... surgical tourniquets are frequently applied in the controlled environment of the operating room in order to control blood loss ... "Ischemia": an inadequate blood supply to an organ or part of the body. Serum lactate level is a proxy measure of tissue ... Surgical tourniquet times in excess of 2 hours have been associated with an increased risk of nerve damage (e.g., neuropraxia ...

*Electrosurgery

Electrosurgical devices are frequently used during surgical operations helping to prevent blood loss in hospital operating ... Appropriately applied with electro surgical forceps, desiccation and coagulation result in the occlusion of blood vessels and ... Its benefits include the ability to make precise cuts with limited blood loss. ... For the high power surgical uses during anesthesia the monopolar modality relies on a good electrical contact between a large ...

*List of MeSH codes (C23)

... blood loss, surgical MeSH C23.550.414.625 --- ecchymosis MeSH C23.550.414.712 --- epistaxis MeSH C23.550.414.756 --- eye ... blood loss, surgical MeSH C23.550.568.500 --- amenorrhea MeSH C23.550.568.750 --- dysmenorrhea MeSH C23.550.568.875 --- ... hearing loss, central MeSH C23.888.592.763.393.341.887.460 --- hearing loss, noise-induced MeSH C23.888.592.763.393.341.887.772 ... hearing loss MeSH C23.888.592.763.393.341.186 --- deafness MeSH C23.888.592.763.393.341.374 --- hearing loss, bilateral MeSH ...

*Yankauer suction tip

A Yankauer can also be used to clear operative sites during surgical procedures and its suctioned volume counted as blood loss ...

*Epinephrine (medication)

... of epinephrine in localized anesthetics also helps to diminish the total blood loss the patient sustains during minor surgical ... A fast heart rate and high blood pressure may occur. Occasionally, it may result in an abnormal heart rhythm. While the safety ... It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil ... While epinephrine does increase aortic, cerebral, and carotid circulation pressure, it lowers carotid blood flow and end-tidal ...

*Surgical humidification

"The effects of mild perioperative hypothermia on blood loss and transfusion requirement". Anesthesiology. 108 (1): 71-77. doi: ... Surgical humidification is the conditioning of insufflation gas with water vapour (humidity) and heat during surgery. Surgical ... Temperature loss during surgery, due to tissue drying, can be prevented by adequately humidifying and heating the CO2. During ... CO2 for open surgery has been conditioned to date with the HumiGard™ Surgical Humidification System. These devices aim to ...

*Surgical shock

It is commonly due to a loss of blood which results in insufficient blood volume. Stewart, John (1999), "Types of surgical ... Surgical shock is the shock to the circulation resulting from surgery. ...

*Thromboelastometry

... and publications recommend that viscoelastic methods such as TEM should be used in surgical procedures where major blood loss ... While in normal blood fibrinolysis activity is quite low, in clinical samples a more rapid loss of clot stability by ... Klinische Wochenschrift 1948;26:577-583 Kozek-Langenecker S. Management of massive operative blood loss. Minerva Anesthesiol ... The rheological conditions mimic the sluggish flow of blood in veins. TEM is performed with the ROTEM whole blood analyzer (Tem ...

*Transoral robotic surgery

TORS afforded cancer cure with less operating time, blood loss, and complication frequency. In light of this data, the FDA ... At the time, surgical robots, in particular the da Vinci Surgical System, were already being used in urologic, thoracic and ... The current literature indicates that the TORS technique results in less blood loss, shorter hospital stays, and lower ... both of which are associated with increased blood loss and infection. There are ongoing clinical trials collecting data on TORS ...

*Ovarian apoplexy

... since delays between the event and surgical intervention increases the magnitude of blood loss and may be life-threatening. ... blood) in the stomach. Because ovarian apoplexy is an acute surgical pathology, diagnosis must be confirmed rapidly, ... depending on the magnitude of blood loss). Treatment depends on the type of ovary apoplexy and the severity of intra-abdominal ... In a general blood test, a marked decrease in hemoglobin levels can be seen (in the anemic and mixed forms of ovarian apoplexy ...

*Haemonetics

... products are marketed to the surgical suite for blood loss management for patients. The products include surgical blood salvage ... surgical field blood suction systems, and blood and patient warming systems). Haemonetics history Arryx acquisition IDM ... automate the processing of blood, support pathogen inactivation and bacterial detection of blood, and test blood hematocrit), ... The Latham Bowl was a disposable container that could automate the separation of blood by centrifugation. Through the 90's, the ...

*Tourniquet (disambiguation)

Surgical tourniquet, a specialised surgical tool Emergency tourniquet, used to stop blood loss in an emergency Tourniquet test ... Tourniquet may refer to: Tourniquet, a medical device used to control blood flow to an extremity: ...

*Emil Theodor Kocher

Kocher is also credited for the invention in 1882 of the Kocher's Surgical Clamp, which he used to prevent blood loss during ... Through application of modern surgical methods, such as antiseptic wound treatment and minimizing blood loss, and the famous ... As a third factor, Hintzsche mentions the minimal blood loss which Kocher achieved. Even the smallest source of blood during ... Kocher's forceps - a surgical instrument with serrated blades and interlocking teeth at the tips used to control bleeding ...

*WHO Surgical Safety Checklist

... the amount of expected blood loss discussed, and an anaesthetic safety check must be completed. Before the surgical procedure ... In each phase, a 'checklist coordinator' must confirm that the surgical team has completed the listed tasks before it proceeds ... "WHO , WHO surgical safety checklist and implementation manual". Who.int. 2010-12-08. Retrieved 2015-04-23. GlobalSurg ... An independent international study at 357 hospitals located in 58 countries has demonstrated that the use of a surgical safety ...

*Acute posthemorrhagic anemia

Acute blood loss is usually associated with an incident of trauma or a severe injury resulting in a large loss of blood. It can ... also occur during or after a surgical procedure. List of circulatory system conditions List of hematologic conditions Turgeon, ... Acute posthemorrhagic anemia or acute blood loss anemia is a condition in which a person quickly loses a large volume of ...

*Gingivectomy

Gingivectomies performed with Diode Lasers or CO2 lasers provide minimal blood loss and reduced discomfort for patients. ... Surgical gingivectomy Gingivectomy by electrosurgery Laser gingivectomy; ...

*Intuitive Surgical

... less blood loss and less need for blood transfusions. Moreover, the da Vinci System can enable a shorter hospital stay, a ... One advantage to DaVinci may well be its ability to extend safe surgical options to more individuals. "INTUITIVE SURGICAL INC ... Intuitive Surgical. Retrieved 2017-11-07. External link in ,website= (help) "Intuitive Surgical." International Directory of ... The da Vinci Surgical System is a robotic surgical system. The system is controlled by a surgeon from a console. It is commonly ...

*Tissuemed

... including a light activated tissue sealant to prevent blood loss during vascular anastomosis, the TissueBond system. More ... In June 2016, Tissuemed won approval from China's FDA for its TissuePatch surgical sealant. AorTech buys TissueMed's heart ... "Tissuemed wins China's OK for TissuePatch surgical sealant - MassDevice". www.massdevice.com. Retrieved 2017-10-16. ... Thereafter Tissuemed focused on the development of innovative tissue adhesives for internal surgical use, ...

*Da Vinci Surgical System

... less blood loss and less need for blood transfusions.[citation needed] Moreover, the da Vinci System can enable a shorter ... The da Vinci Surgical System is a robotic surgical system made by the American company Intuitive Surgical. Approved by the Food ... A study published in the Journal of the American Medical Association found that side effects and blood loss in robotically- ... ZEUS robotic surgical system, a rival system discontinued in 2003 "Robots as surgical enablers". MarketWatch. 3 February 2005. ...

*Stomach disease

... it can even cause severe blood loss (anemia) or lead to perforation (hole) in the stomach which is a surgical emergency. In ... Symptoms include abdominal pain, loss of appetite, and weight loss. Diarrhea is also a symptom that can develop, so checking ... Presence of blood in stools is often the first sign that there is a problem in the stomach. Another very common long term ... When the condition is allowed to progress, the pain may become continuous; blood may start to leak and be seen in the stools. ...

*London's Air Ambulance

... surgical and non-surgical Rapid Sequence Induction (RSI), pelvic splinting (crucial to prevent blood loss in high impact ... and carry blood on board and administer blood transfusion on the roadside. In 2014 London's Air Ambulance performed the first ... The service started a trial of a portable brain scanner which can detect blood clots on the brain in April 2015. The current ... Neil Bowdler (6 March 2012). "Air ambulance first in UK to carry blood". BBC. Retrieved 6 March 2012. Cost details outlined at ...

*Hemolysis

In some surgical procedures (especially some heart operations) where substantial blood loss is expected, machinery is used for ... Unfortunately, increased hemolysis occurs with massive amounts of sudden blood loss, because the process of returning a ... A centrifuge process takes blood from the patient, washes the red blood cells with normal saline, and returns them to the ... by the effects of mechanical processing of blood, or by bacterial action in cultured blood specimens. Most causes of in vitro ...

*Childbirth

Heavy blood loss leads to hypovolemic shock, insufficient perfusion of vital organs and death if not rapidly treated. Blood ... The midwife or obstetrician may decide to make a surgical cut to the perineum (episiotomy) to make the baby's birth easier and ... Hemorrhage, or heavy blood loss, is still the leading cause of death of birthing mothers in the world today, especially in the ... blood pressure(rarely taken on newborns in the pre-hospital setting) oxygen saturation, blood sugar, and EKG monitoring. They ...
Accurately quantifying surgical blood loss can be critical as a clinical trial outcome, and understanding estimated blood loss is important to patient care. In addition to visual estimates, anthropometric and laboratory data can be used to estimate surgical blood loss. In this infographic, we review recent work that utilized an existing data set to compare directly measured surgical blood loss to 3 previously described methods of estimating surgical blood loss and one newly derived approach.1 Hct indicates hematocrit; EBV, estimated blood volume; Hcti, initial hematocrit; Hctf, final hematocrit. ...
TY - JOUR. T1 - Does Prophylactic Administration of TXA Reduce Mean Operative Time and Postoperative Blood Loss in Posterior Approach Lumbar Spinal Fusion Surgery Performed for Degenerative Spinal Disease?. AU - Larson, Evan. AU - Evans, Tyler. AU - Long, Jake. AU - Gannon, Emmett. AU - Lyden, Elizabeth. AU - Cornett, Chris Alan. PY - 2019/8/1. Y1 - 2019/8/1. N2 - Study Design:This is a level III retrospective cohort study.Objective:To investigate association between prophylactic tranexamic acid (TXA) administration before 1 and 2-level posterior lumbar interbody fusion operations and perioperative blood loss (including intraoperative blood loss and postoperative drain output), mean operative time, postoperative transfusion, and postoperative venous thromboembolic events.Summary of Background Data:TXA is a systemic antifibrinolytic that competitively inhibits lysine binding sites on plasminogen, reversibly blocking its binding to fibrin and impeding fibrinolysis and clot degradation. TXAs role ...
Introduction: The estimation of blood loss rate during surgery for prediction of transfusion of blood or blood products requirement is important for surgeon and anesthesiologist. In regard to various results and lack of definite index for start of transfusion in operating rooms, the assessment of blood loss reduction is necessary. The aim of study was evaluation of hemoglobin (Hb) value and hemorrhage estimation rate. Methods and materials: 48 cases underwent major orthopedic surgery with high probability of intraoperative blood loss rate was included in study. Hb, hematocrit (Hct) and basic vital signs were measured preoperatively and blood loss rate was estimated by using of blood volume in suction, bloody gases and blood loss in operation field and recorded. The blood sample per 100 mL blood loss was sent to laboratory. For transfusion deciding based on Hb, we did not any intervention. Results: 26 males and 22 females were included in study. Our results showed that Hb value of males was higher
Background Ahead of routine screening process of blood items many sufferers with haemophilia were infected with hepatitis C computer virus (HCV) Zaurategrast and have subsequently gone on to develop end-stage liver disease (ESLD). and 4 (22%) experienced hepatocellular carcinoma. Median intra-operative blood loss was 4.2 l (range 0.8-12) and all received coagulation factor support peri-operatively. Coagulation was unsupported by 72 h post-operatively in all recipients. Two sufferers developed problems as a complete consequence of post-operative bleeding. At a median follow-up of 90 a few months 8 sufferers have passed away including 4 from the 5 sufferers which were HIV positive. The median success of sufferers with and without HIV co-infection was 26 and 118 a few months respectively. Bottom line LT in sufferers with haemophilia treatments the coagulation disorder and in the Zaurategrast lack of HIV/HCV co-infection is certainly connected with long-term individual success. = 5) ahead of 1997 or ...
... - Health - Scotsman.com use above link to read full article http://www.scotsman.com/webimage/7.25526.1336490729%21image/3142543874.png_gen/derivatives/default/3142543874.png http://www.scotsman.com/logger/p.gif?a=1.2481028&d=/2.6543/2.7475/2.7480
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BACKGROUND: Open simple prostatectomy has long been associated with large blood losses; hence allogeneic blood transfusion in this procedure is a standard practice world over. A review of literature suggests significant association between perioperative blood loss accompanying open simple prostatectomy and certain patient factors. The shortage of blood and blood products in our blood transfusion centres as well as the alarming risks of transfusion reactions and disease dissemination demanded a review of these factors with the aim of reducing morbidity associated with peri-operative blood loss and blood transfusion. OBJECTIVES: To assess blood loss, determine blood transfusion rate, and define some of the factors associated with peri-operative blood loss and blood transfusion in open simple prostatectomy. DESIGN : A prospective cohort study. SETTINGS: The urology units of Kenyatta National Hospital, Kenya. RESULTS: Ninety five patients who underwent open simple prostatectomy for benign prostatic ...
BACKGROUND:Visual estimation and gravimetric methods are commonly used to quantify the volume of blood loss during cesarean delivery (CD). However, the correlation between blood loss and post-CD hemoglobin (Hb) is poorly studied, and it is unclear whether the correlation varies according to how bloo
Considering the potential impact on patients and decision making, these findings may be important to ED care. The types of situations assessed in the study were found to lead to both low precision and poor accuracy in estimating blood loss. Emergency physicians should be aware of the potential for inaccuracies in making and using these estimates in clinical care.. Future research should explore various interventions that may improve the ability to estimate blood loss during clinical decision making. More information on the value of adding these estimation skills to emergency medicine training is also warranted. Training programs to enhance the estimation skills of physicians should be tested, evaluated, and, if successful, incorporated into emergency medicine and advanced trauma care. Many factors can lead to poor estimation of blood loss, especially during early evaluations. The key is to interpret blood loss estimates with great caution. ...
Ama : Total diz veya kal a artroplastisinden sonra yayg n olarak g r len gizli kan kayb (GKK), g r lebilir kan hacmi kayb na dayanan reinf zyon veya kan nakli sonras nda bile postoperatif anemiye neden olur. Son y llarda yap lan al malar oksidatif stresin GKK yla ili kili olabilece ini g stermi tir. Bununla birlikte, proantosiyanidin (PA) veya hidrojenli su (HS) antioksidanlar n n GKK yi iyile tirip iyile tirmedi i anla lamam t r. Bu al man n amac PA ve HS nin GKK zerindeki etkilerini de erlendirmektir ...
Ama : Total diz veya kal a artroplastisinden sonra yayg n olarak g r len gizli kan kayb (GKK), g r lebilir kan hacmi kayb na dayanan reinf zyon veya kan nakli sonras nda bile postoperatif anemiye neden olur. Son y llarda yap lan al malar oksidatif stresin GKK yla ili kili olabilece ini g stermi tir. Bununla birlikte, proantosiyanidin (PA) veya hidrojenli su (HS) antioksidanlar n n GKK yi iyile tirip iyile tirmedi i anla lamam t r. Bu al man n amac PA ve HS nin GKK zerindeki etkilerini de erlendirmektir ...
Intraoperative transit time flow meters & flow probes for every OR suite. In surgery confirm clinical impressions with objective flow measurement data.
While the occurrence of blood loss per rectum in general practice is common and usually not serious, it may be the first symptom of a colorectal malignant disorder. To determine the occurrence and clinical significance of overt blood loss per rectum a Medline literature search was undertaken. The incidence of this symptom in the general population was reported to be approximately 20 per 100 people per year, the consultation incidence in general practice approximately six per 1000 and the incidence of referral to a medical specialist was estimated to be about seven per 10,000 per year. The clinical significance of the symptom varied within different populations: the predictive value of overt rectal blood loss for colorectal malignancy was estimated to be less than one in 1000 in the general population, approximately two in 100 in general practice and up to 36 in 100 in referred patients. How the manifestation of the bleeding (and other signs and symptoms) contributes to the selection of ...
Compare and contrast the composition of blood plasma and glomerular filtrate. Your friend is in a car accident and experiences a substantial amount of blood loss. The emergency room doctor tells you he is sending your friend to.
Tips to help with your thrombocytopenia: Acute Blood Loss Thrombocytopenia. My thrombocytopenia, Online resources for thrombocytopenia.
Gastrointestinal bleeding occurs as a result of blood loss from somewhere in the gastrointestinal tract, the passage that extends from the mouth to the anus.
Objective: To assess the effect of tourniquet application of intraoperative blood loss in placenta accreta cases undergoing cesarean hysterectomy. Materials and methods: Nine cases and twenty controls with USG and colour Doppler diagnosed placenta accreta with previous cesarean section were chosen to utilize this _disibledevent= 0.0002). No intra-operative or post-operative surgical complications were observed in any of the cases whereas the controls reportedly had a few. All the mothers and babies were healthy at the time of discharge. Conclusion: The presence of placenta accreta is associated with major fetal and maternal complications. The technique of tourniquet application is efficacious in minimizing the intra-operative blood loss and surgical complications due to obstruction of operative field by bleeding and also by preventing massive blood transfusion related complications.
TY - JOUR. T1 - Detection of homologous blood transfusion. AU - Voß, Sven. AU - Thevis, Mario. AU - Schinkothe, T.. AU - Schänzer, Wilhelm. PY - 2007. Y1 - 2007. N2 - The aim of the present study was to improve and validate a flow cytometric method for the detection of homologous blood transfusion in doping control analysis. A panel of eight different primary antibodies and two different phycoerythrin-conjugated secondary antibodies was used for the detection of different blood populations. The flow cytometer used in this study was the BD FACSArray® instrument. Mixed red blood cell populations were prepared from phenotype known donors. Linearity, specificity, recovery, precision, robustness and interday-precision were tested for every primary antibody used in the presented assay. The technique of signal amplification was utilized for an improved separation of antigens with weak or heterozygous expression to improve the interpretation of histograms. The resulting method allowed to clearly ...
Blood transfusion is administered during many types of surgery, but its efficacy and safety are increasingly questioned. Evaluation of the efficacy of agents, such as desmopressin (DDAVP; 1-deamino-8-D-arginine-vasopressin), that may reduce perioperative blood loss is needed.To examine the evidence for the efficacy of DDAVP in reducing perioperative blood loss and the need for red cell transfusion in people who do not have inherited bleeding disorders.We searched for randomised controlled trials (RCTs) in the Cochrane Central Register of Controlled Trials (2017, issue 3) in the Cochrane Library, MEDLINE (from 1946), Embase (from 1974), the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (from 1937), the Transfusion Evidence Library (from 1980), and ongoing trial databases (all searches to 3 April 2017).We included randomised controlled trials comparing DDAVP to placebo or an active comparator (e.g. tranexamic acid, aprotinin) before, during, or immediately after surgery or after
Product Name: Tranexamic Acid Injection. Common Name: antifibrinolytic injection. Strength: 100 mg / ml. Description: Tranexamic acid belongs to the class of medications called antifibrinolytic agents. Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.. Indications and Usage:. Tranexamic acid medication is used to prevent or reduce bleeding in certain conditions, such as dental surgery in people with hereditary blood clotting disorders, cervical surgery, heavy menstrual bleeding, nose bleeds and bleeding inside the eye.. In some medical conditions, the body breaks down blood clots too fast, not allowing the bleeding to stop and the wound to heal. Tranexamic acid works by blocking the breakdown of clots in the body.. Pack Size: Tranexamic Acid Injection is available in 5ml.. Minimum Order Quantity: 3000 ...
Most of the above-mentioned procedures can be performed with the assistance of robotic technology. Gynecologic surgeons at the University of Florida are proud to utilize the most advanced robotic technology in the world. Two da Vinci Si robotic systems are housed at Shands at UF and are used routinely for a myriad of gynecologic procedures such as hysterectomy, myomectomy, sacrocolpopexy and adnexal surgery. The da Vinci system provides superior 3-D quality visualization and magnification, along with the precision afforded with its unique wristed instruments. Robotic and minimally-invasive approaches offer significant benefits over traditional open surgery, such as less surgical blood loss, less scarring, less pain, better cosmetic results and faster recovery and return to regular activities. Most patients are able to leave the hospital within 24 hours.. ...
Total knee arthroplasty usually has an important blood loss which may lead patients to receive allogeneic blood transfusion up to 30-45% of cases. Allogeneic blood transf..
Since the successful perioperative use of rhEPO more than 5 years ago in an animal model, many reports (1) have detailed its use in clinical medicine. The investigation by Biesma and colleagues joins a growing list of studies that support the preoperative clinical use of rhEPO as an adjunct to decrease allogeneic (homologous) red blood cell use (1, 2). Their study is also unique in that it helps to define specific groups of patients who may most benefit from preoperative rhEPO, namely, those autologous blood donors with blood volumes , 5 L. Autologous blood collection services currently allow many patients who are having elective surgery to bank their own blood. As much as 60% of the autologous blood collected in the United States, however, does not get transfused. In the study by Biesma and colleagues, 54% (27 of 50) of the patients in the rhEPO-treated group were not transfused with any red blood cells. The cost to the hospital pharmacy for rhEPO is approximately $10 per 1000 units, which ...
As French physicians frequently and currently deployed in Theater of Operations in Africa, we read with interest the article by Ariyo et al.1 reviewing the anesthesia care provided at Médecins Sans Frontières facilities between 2008 and 2014. Spinal anesthesia was the most common type of anesthetic technique (34,413 [45.56%]), with cesarean section being the most common type of procedure performed (26,091 [34.54%]). Wound surgeries represented another common procedure type included in this retrospective study (18,547 [24.55%]). In this context, perioperative deaths occurred in 72 (0.21%) cases of obstetrics/gynecology and urology surgery and in only seven (0.06%) cases of wound surgeries. Nevertheless, the authors did not provide any details regarding the causes of death or any details about the incidence of perioperative bleeding and perioperative blood management. Perioperative blood management refers to perioperative blood transfusion and adjuvant therapies.2 Perioperative blood transfusion ...
To the editor: Kobrinsky and associates (1) show that patients receiving 1-desamino-8-D-arginine vasopressin (desmopressin) had a decreased blood loss during Harrington rod spinal fusion surgery. The authors speculate that the decreased blood loss was due to various hematologic effects of desmopressin and conclude that "the use of desmopressin in other surgical procedures associated with significant blood loss is recommended.". This conclusion is probably unwarranted. Intraoperatively "a balanced technique with normotension" was used. Unless specifically contraindicated, induced hypotension with a mean blood pressure of about 70 torr is the accepted anesthetic technique (2). This is done to minimize intraoperative blood loss. ...
University of the District of Columbia. J. Treslott, MD: "Purchase Tranexamic Acid - Trusted online Tranexamic Acid no RX".. Because it is impossible to maintain perfect insulation tranexamic 500mg generic medications j tube, the inner container is continually trying to draw heat from the atmosphere order tranexamic 500mg visa medications hyperthyroidism, though this is partially offset by the evaporation of liquid during use tranexamic 500mg with mastercard medications dictionary. If there is no demand, the pressure inside the vessel will rise, causing the safety relief valve to vent gas to atmosphere; to avoid this, the fow valves are designed to open under high pressure and permit gas to pass into the pipeline distribution line. When this happens, liquid is withdrawn from the inferiorly located liquid valve and passed through a pressure-raising coil which raises the pressure to 10. This can be either a simple ambient vaporizer or duplex timed automatic • a main vessel containing operational ...
A growing body of evidence has shown tranexamic acid (TXA) to be effective in decreasing perioperative blood loss and transfusion requirements in both primary and revision hip and knee arthroplasty.
Autotransfusion Services is a unique specialty that includes collecting and returning shed blood from the surgical field to significantly reduce or eliminate the need for blood transfusions.
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... , an antifibrinolytic, is used off label to reduce bleeding in certain kinds of surgery, including major orthopedic and spine
List of 5 disease causes of Blood loss in adolescents causing anemia, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Blood loss in adolescents causing anemia.
Nanoparticles are capable of aggregating at injury sites and helping in clotting. This helps control blood loss, and may save lives without need for major surgery.
CRASH-2 trial came out in 2010 to answer this question: What are the effects of the early administration of a short course of tranexamic acid on death in trauma patients with or at risk of significant haemorrhage? CRASH-2 trial is a large placebo controlled trial undertaken in 276 hospitals in 40 countries. Discussion: Patients were included if the…
This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia.
5.0603 -42.8239 SADLY, the deaths of 29-year-old conjoined Iranian twins during surgery prove that despite numerous strides in medical science, such delicate and risky surgery has a long way to go.. More than 50 hours into what was to have been four days of surgery in Singapore, Ladan Bijani died. Her sister Laleh died 90 minutes later. Both deaths were blamed on blood loss.. The sisters understood that the risks of surgery were high. Joined at the head, with brains that not only shared a vein but had fused over the years, the women so desperately desired to live separately that they willingly and courageously faced the possibility that one, or both of them, could die in the process.. That should be stressed more than trying to fix blame.. The adoptive father of the two was bitter. "When they took them to Singapore I knew they would bring back their bodies," Alireza Safian said. "They took them there and killed them.". His emotional state is understandable if way off the mark.. Other adult ...
Blood transfusion is a life-saving intervention for subjects with acute blood loss or hematological disturbance, and approximately 5 million people per year rec...
A newborn died in a waterbirth and another mother died from blood loss after the delivery of her baby, according to a new report on serious events in NZ h
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In the acute normovolemic hemodilution group, intraoperative blood collection was performed to a target hemoglobin of 8.0 g/dL. Low central venous pressure anesthetic technique was used intraoperatively for both groups. A standardized transfusion protocol was applied to all patients intraoperatively and throughout the hospital stay.. The researchers randomized 63 patients to acute normovolemic hemodilution, and 67 to standard anesthetic management from 2004 to 2007.. Demographics, diagnoses, liver function, extent of resection, intraoperative blood loss, operative time, incidence and grade of complications, and length of hospital stay were similar between the 2 groups. The team found that acute normovolemic hemodilution reduced the overall allogeneic red cell transfusion rate by 50% compared with standard anesthetic management. Acute normovolemic hemodilution patients were less often transfused intraoperatively compared with the standard anesthetic management group.. The research team noted that ...
UNLABELLED The erythropoietic capacity for preoperative autologous blood donation (ECPABD) shows marked inter individual variability. This study was performed to evaluate factors useful to predict individual ECPABD from data available before the first donation. The subjects consisted of 74 adult patients who received autologous blood donation, with a mean of 61 +/- 12.8 yr (SD). We classified the patients into four groups using our criteria for evaluating the ECPABD and investigated the relationships among age, disease, pre-platelet count, and the rate of platelet increase. RESULTS (1) Advanced age and the status of disease were not distinctly correlated with low ECPABD. (2) Patients with a high pre-platelet levels had a low ECPABD regardless of the haemoglobin. (3) Patients in which the platelet count increased in accordance with the level of collection exhibited low pre-platelet counts and high ECPABD. CONCLUSION In patients with high pre-platelet levels, we reduced the amount collected,
Context: Intraoperative blood loss during open lumbar spine surgery is associated with adverse events and is a contributor to higher medical costs. Intraoperative hypothermia has been shown to increase blood loss and postoperative allogeneic blood transfusion rates in other realms of orthopedic surgery, but it has not been studied extensively in patients undergoing spine surgery. Objective: To determine whether a clinically relevant association exists between intraoperative core body temperature and blood loss or transfusion rates in adult patients undergoing open lumbar spine surgery. Methods: In this retrospective medical record review, the surgical records of 174 adult patients who underwent open, nonmicroscopically assisted lumbar spine surgery performed by a single surgeon at a single institution were evaluated. Maximum, minimum, and average temperature, hypothermic temperature, and temperature range parameters were compared with intraoperative, total, and net blood loss and blood ...
BACKGROUND The objective of this meta-analysis was to evaluate the efficacy and safety of tranexamic acid (TXA) in shoulder arthroplasty (SA). METHODS Academic articles were identified from the Cochrane Library, Medline (1966-2017.2), PubMed (1966-2017.2), Embase (1980-2017.2), and ScienceDirect (1966-2017.2). Randomized controlled trials (RCTs) and non-RCTs studying TXA in SA were included. Two independent reviewers conducted independent data abstraction. The I statistic was used to assess heterogeneity. Fixed- or random-effects models were used for meta-analysis. RESULTS Two RCTs and 2 non-RCTs met the inclusion criteria. This meta-analysis found significant differences in postoperative hemoglobin reduction (MD = -0.71 g/dL), drainage volume (MD = -133.21 mL), and total blood loss (MD = -226.82 mL) between TXA groups and controls. There were no significant differences in blood transfusion requirements, operation time, or length of hospital stay. CONCLUSIONS The use of TXA in SA decreases
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in various types of major surgery (orthopedic surgery, spine surgery, cardiopulmonary bypass, liver resections, and gynecological cancers).The current trial is being conducted to compare the efficacy of tranexamic acid plus standard of care versus standard of care in reduction of blood loss in patients undergoing major abdominal surgeries ...
Preoperative autologous collections are most beneficial to those patients who are undergoing procedures with substantial anticipated blood loss, such as orthopedic joint replacement, vascular surgery, cardiac or thoracic surgery, and radical prostatectomy. Autologous blood is unnecessary for procedures that seldom require transfusion, such as transurethral resection of the prostate, cholecystectomy, herniorrhaphy, vaginal hysterectomy, and uncomplicated obstetric delivery [14]. A hospitals maximal surgical blood order schedule for blood cross-match can provide estimates of transfusion rates for specific procedures; the generally accepted cutoff at which transfusion is unlikely and autologous blood procurement should not be recommended is 10% [15].. Collection of units should be scheduled as far in advance of surgery as possible for liquid blood storage (up to 42 days), to allow compensatory erythropoiesis [5] to correct the induced anemia. If the erythropoietic response to autologous blood ...
The optimal application of tourniquet should reduce perioperative blood loss, create bloodless operative field, improve cementing technique and shorten surgery time. Meanwhile, inadequate application may increase the risk of deep vein thrombosis and pulmonary thromboembolism. Previous attempts to compare the tourniquet strategies in respect to the perioperative blood loss did not show significant difference. The investigators use the volume loading test aiming to optimize the fluid status and obtain the hemoglobin concentration in the conditions of standardized plasma dilution. The test is deployed just before the surgery and after postoperative 24 hrs in ICU. Functional outcomes and possible length of hospital stay is also evaluated ...
Background Blood salvage systems help to minimize intraoperative transfusion of allogenic blood. So far no data is available on the use of argatroban for anticoagulation of such systems. We conducted...
Abstract  As a large amount of blood loss is sometimes encountered in limb salvage procedures for pelvic tumours, it is essential to identify risk factors predicting the possibility of extensive haemorrhage. We retrospectively reviewed 137 patients who underwent pelvic tumour resections. Patients with an estimated blood loss greater than 3,000 ml were classified as having a large amount of blood loss. Sixty-one (44.53%) patients had blood loss greater than 3,000 ml. Tumours involving the acetabulum or sacrum, tumour volume greater than 400 cm3, aorta occlusion, resection method, reconstruction and operative time were all associated with a large amount of blood loss. Pelvic tumours involving the acetabulum or sacrum (odds ratio: 4.837), tumour volume greater than 400 cm3 (odds ratio: 3.005) and planned operation time of more than 200 min (odds ratio: 3.784) independently predicted a large amount of blood loss. Pelvic tumours with these characteristics were likely to have a large ...
The purpose of this meta-analysis is to evaluate the efficacy and safety of tranexamic acid (TXA) for patients with degenerative lumbar disc herniation, stenosis or instability undergoing posterior lumbar fusion (PLF) surgery. We searched PubMed, Embase, and Cochrane Library until May 1, 2018. Two reviewers selected studies, assessed quality, extracted data, and evaluated the risk of bias independently. Weighted mean difference (WMD) and relative risk (RR) were calculated as the summary statistics for continuous data and dichotomous data, respectively. We chose fixed-effects or random-effects models based on I2 statistics. RevMan 5.0 and STATA 14.0 software were used for data analysis. Nine studies enrolling 713 patients for the study. The pooled outcomes demonstrated that TXA can decrease total blood loss (TBL) in patients underwent PLF surgery [WMD = -250.68, 95% CI (− 325.06, − 176.29), P|0.001], intraoperative blood loss (IBL) [WMD = -72.57, 95% CI (− 103.94, − 41.20), P|0.001],
Since fibrinogen plays a key role in hemostasis and it is rapidly depleted during cardiac surgery, many cardiac surgeons give fibrinogen to control bleeding during surgery for high-risk patients. The efficacy of this treatment, however, had not been previously confirmed in large, randomized clinical trials. A recent study in the Netherlands randomized 120 high-risk cardiac surgery patients with intraoperative bleeding to receive either fibrinogen concentrate or a placebo during elective surgery. Over 70% of the surgeries were either coronary artery bypass grafts or valve repair or replacements, and the surgeries on average lasted more than three hours. Intraoperative blood loss was similar in both groups-the median blood loss in the patients that received fibrinogen concentrate was 50 mL (IQR 29-100 mL) while the group receiving the placebo lost a median of 70 mL of blood (IQR 33-145 mL; p=0.19). Furthermore, additional adverse events occurred in the patients who received fibrinogen up to 30 ...
The risk-benefit balance of using tranexamic acid in cardiac surgical patients remains unclear. While tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, there are concerns that it may have prothrombotic and proconvulsant effects. In a trial with a 2-by-2 factorial design, patients scheduled to undergo coronary-artery surgery and at risk for perioperative complications were randomly allocated to receive aspirin or placebo and tranexamic acid or placebo. The results of the tranexamic acid comparison are reported here. The primary outcome was a composite of death and thrombotic complications (nonfatal myocardial infarction, stroke, pulmonary embolism, renal failure, or bowel infarction) within 30 days after surgery. Four thousand six hundred thirty-one patients underwent surgery and had available outcome data. A primary outcome event occurred in 386 patients (16.7%) in the tranexamic acid group and in 420 patients (18.1%) in the placebo group (relative risk, ...
Introduction In spinal tumors treatment, the surgical intervention aims toward decompression, either by direct removal of metastatic tissue or indirectly by palliative posterior laminectomy. These operations can be usually performed without any major bleeding problem. After meta-analysis of 18 papers, Chen et al. reported average estimated perioperative blood loss to be 2180 ml.1
The evidence in this review suggests that the uncertainty about the effect of tranexamic acid on blood transfusion in surgical patients was resolved over a decade ago; however, uncertainties about its effect on thromboembolic events and mortality persist. Despite this, trials of tranexamic acid continue to assess the effect on blood transfusion. One reason may be a reluctance to generalise the evidence across surgery types, although there is no evidence that the relative effect of tranexamic acid on blood transfusion varies by type of surgery. A second reason may be that trialists are unaware of the existing evidence when initiating a new trial. Our observation that only half of the trials cited one or more of the available systematic reviews and just two carried out their own systematic review, does suggest that many trialists are indeed failing to adequately consider the existing evidence.. Blood is a scarce and costly resource and blood transfusion is not without risk. The cost of a unit of ...
Tranexamic acid injection is an antifibrinolytic agent. It works by blocking the breakdown of blood clots. It may also be used for other conditions as determined by your doctor. This medicine is available only with your doctors prescription. This product is available in the following dosage forms:. ...
Intravenous literature: Veenith, T., Sharples, L., Gerrard, C., Valchanov, K. and Vuylsteke, A. (2010) Survival and length of stay following blood transfusion in octogenarians following cardiac surgery. Anaesthesia. 65(4), p.331-336. Abstract: Our aim was to assess if peri-operative blood transfusion is an independent risk factor for mortality and morbidity in the elderly. We report the…
2017 The American Society of Colon and Rectal Surgeons, Inc. BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. OBJECTIVE: The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. DESIGN: This was a prospective, double-blind, placebo-controlled, randomized clinical trial. SETTINGS: The study was conducted at a tertiary referral university hospital in Australia. PATIENTS: Consecutive patients aged ,18 years with lower GI hemorrhage requiring hospital admission from November 2011 to January 2014 were screened for trial eligibility (N = 265). INTERVENTIONS: A total of 100 patients were recruited after exclusions and were randomly assigned 1:1 to either tranexamic acid or placebo. MAIN OUTCOME MEASURES: The ...
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A blood transfusion is when blood or parts of the blood are given to a person through an IV line placed in a vein. The blood and blood parts used for transfusion are called blood products. The blood usually comes from another person (donor). This sheet tells you more about how blood and blood products may be used to help treat cancer.
Tranexamic acid is a blood-clotting agent used in everything from soldiers wounds to dental surgery. It can cost as little as $1 a dose.
The best Price Compare 300g Rapid delivery 99%Tranexamic acid Powder with free shipping for skin care from Publishing house ,are high quality product. It could be a quite wonderful ware for the value. Youll be able to scan review via shoppers to discover added off their earlier encounters. The shoppers suggestions will give you a nice recommendation on the value and nice atonement with the goods ...
Pratschke, S.; Rauch, Alexandra; Albertsmeier, M.; Rentsch, M.; Kirschneck, Michaela; Andrassy, J.; Thomas, M.; Hartwig, Werner; Figueras, J.; Del Rio Martin, J.; de Ruvo, N.; Werner, Jens; Guba, M.; Weniger, Maximilian und Angele, Martin Kurt (2016): Temporary Intraoperative Porto-Caval Shunts in Piggy-Back Liver Transplantation Reduce Intraoperative Blood Loss and Improve Postoperative Transaminases and Renal Function: A Meta-Analysis. In: World Journal of Surgery, Vol. 40, Nr. 12: S. 2988-2998 ...
Hospitals face a range of challenging issues. For you, patient safety is of paramount concern, but it doesnt end there. You are also called upon to provide the highest standard of patient care, while at the same time containing your operating costs and managing your blood supply in order to optimize usage and minimize waste. To do this effectively, you need access to high-quality products and services that can help improve your blood management programs. We have a range of devices, software, and services available to help you: ...
Surgeons always try to carry out surgery to minimise the amount of blood lost. In recent years, this has become easier, due to the increasing use of keyhole surgery (laparoscopic surgery), where only small cuts are made in the body.. However, some types of surgical operations and procedures have a higher risk of blood loss; therefore, a blood transfusion is more likely to be needed. It may be possible to use a procedure called intra-operative cell salvage. It collects your blood thats lost during the surgery, and it can be returned back to you. Ask your doctor or nurse if intra-operative cell salvage is appropriate for the type of surgery youre having.. Its no longer possible to routinely collect your own blood in advance of your surgery.. ...
Autotransfusion Services is a unique specialty that includes collecting and returning shed blood from the surgical field to significantly reduce or eliminate the need for blood transfusions ...
There are three main reasons people become anemic: blood loss, a reduction in the bodys ability to produce new red blood cells, or an illness that leads to increased destruction of red blood cells.. Blood loss. When the amount of blood lost is greater than your bodys ability to replace the lost red blood cells, you can become anemic. Women who experience heavy menstrual periods, for example, and people who have internal bleeding due to ulcers or other digestive problems are at the greatest risk for anemia. Sometimes this type of blood loss is silent and unrecognized until anemia shows up on a blood test. External bleeding from surgery or trauma also can cause anemia.. Low production of red blood cells. Even if youre not bleeding, old red blood cells constantly need to be replaced with new ones.. A number of factors can cause your body to produce too few red blood cells, or red blood cells lacking in sufficient hemoglobin.. These include: ...
To install a popular screen saver, select the desired screen saver from the screen saver website, and then download the screen saver by clicking on the Download button. Click on the executable screen...
Learn about the potential side effects of Lysteda (tranexamic acid). Includes common and rare side effects information for consumers and healthcare professionals.
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Pringle, Gary Johnson, who is currently in a tube at Chutney on the Fritzs branch of Tesco, (other shopping emporia are available, guys and girls), has revealed that he is not looking forward to his visit to a strangers stomach. I know that it...
Menstruation varies from person to person, making it harder to distinguish normal from excessive blood loss. So how do you tell what is
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The Consensus Document on Alternatives to Allogenic Blood Transfusion (AABT) has been drawn up by a panel of experts from 5 scientific societies. The Seville Consensus Document on Alternatives to Allogenic Blood Transfusion
Total knee arthroplasty is regarded as the most effective treatment for severe knee osteoarthritis. The influential factors of blood loss in total knee arthroplasty remain controversial. The study aims to explore the influential factors of blood loss in total knee arthroplasty comprehensively. Three hundred and four osteoarthritis patients undergoing unilateral primary total knee arthroplasty were enrolled. Demographic characteristics, laboratory results, surgical protocol, and hemostatic and anticoagulation drugs were collected. Estimation of blood loss was calculated using the Gross equation. Multivariable stepwise linear regression analysis was performed to find out the influential factors. Total blood loss reached the biggest volume (1346 ± 671 mL) in the post-operative third day. Hidden blood loss reached 465 ± 358 mL. Gender, tranexamic acid, prosthesis type, and drainage were proven to be positively correlated with the total blood loss (all P | 0.05). Male appeared to suffer more surgical blood
TY - JOUR. T1 - Systematic review of the use of fibrin sealant to minimize perioperative allogeneic blood transfusion. AU - Carless, Paul A.. AU - Anthony, Danielle M.. AU - Henry, D. A.. PY - 2002. Y1 - 2002. N2 - Background: Fibrin sealants have become popular in improving perioperative haemostasis and reducing the need for allogeneic red cell transfusion. Methods: A systematic review of randomized controlled trials was conducted to examine the efficacy of fibrin sealants in reducing perioperative blood loss and allogeneic red blood cell transfusion. Studies were identified by computer searches of Medline, Embase, Current Contents, the Cochrane Library, manufacturer websites (to January 2001), and bibliographic searches of published articles. Trials were eligible for inclusion if they involved adult elective surgery and reported quantitative data on blood loss, the proportion of patients exposed to allogeneic red cell transfusion and/or the volume of blood transfused. Results: Twelve trials ...
Background and Aims: Tranexamic acid has been used to decrease blood loss volumes and the subsequent need for blood transfusion in the orthopedic, spinal and cardiac surgeries. Methods: In this prospective controlled randomized clinical trial study, 24 candidates for orthognathic surgeries received tranexamic acid (20 mg/kg) intravenously just before the surgery while matched control patients received normal saline. The patients underwent the surgeries according to the standard protocol. Patients blood hemoglobin and hematocrit levels were calculated before and after the surgeries and blood loss volumes were calculated using these criteria. Results: The blood loss was estimated as 693.65 ± 81.24 and 1024.00 ± 75.41 ml regarding blood hemoglobin values before and after the surgery in intervention and control groups, respectively; while it was estimated as 660.93 ± 62.78 and 1052.00 ± 48.54 ml concerning patients blood hematocrit levels before and after the surgery in those groups, respectively.
Autotransfusion is a process wherein a person receives their own blood for a transfusion, instead of banked allogenic (separate-donor) blood. There are two main kinds of autotransfusion: Blood can be autologously "pre-donated" (termed so despite "donation" not typically referring to giving to ones self) before a surgery, or alternatively, it can be collected during and after the surgery using an intraoperative blood salvage device (such as a Cell Saver or CATS). The latter form of autotransfusion is utilized in surgeries where there is expected a large volume blood loss - e.g. aneurysm, total joint replacement, and spinal surgeries. The first documented use of "self-donated" blood was in 1818, and interest in the practice continued until the Second World War, at which point blood supply became less of an issue due to the increased number of blood donors. Later, interest in the procedure returned with concerns about allogenic (separate-donor) transfusions. Autotransfusion is used in a number of ...
Background:Proximal Femoral shaft fractures are commonly associated with marked blood loss which can lead topostoperative acute anemia and some other complications.Tranexamic acid (TA) is an antifibrinolytic medication that reduces intra-and postoperative blood loss and transfusionrequirements during some elective surgeries (1-3).The aim of this study is to evaluate the effect of intravenous Tranexamic acid (TA) on intraoperative blood loss and asubsequent need for transfusion in patients who were undergoing surgery for femoral shaft fractures in trauma setting.Methods:Thirty-eight ASA grade I-II patients undergoing proximal femoral shaft fracture surgery with intra medullarynailing were included in this double blind randomized controlled clinical trial. They were allocated into two groups. GroupI, the intervention group with eighteen patients received 15 mg/kg (TA) via intravenous infusion before surgical incision.Patients in the placebo group received an identical volume of normal saline.Hemoglobin
Looking for online definition of Gastrointestinal Blood Loss Scan in the Medical Dictionary? Gastrointestinal Blood Loss Scan explanation free. What is Gastrointestinal Blood Loss Scan? Meaning of Gastrointestinal Blood Loss Scan medical term. What does Gastrointestinal Blood Loss Scan mean?
TY - JOUR. T1 - Early autologous fresh whole blood transfusion leads to less allogeneic transfusions and is safe. AU - Rhee, Peter. AU - Inaba, Kenji. AU - Pandit, Viraj. AU - Khalil, Mazhar. AU - Siboni, Stefano. AU - Vercruysse, Gary. AU - Kulvatunyou, Narong. AU - Tang, Andrew. AU - Asif, Anum. AU - OKeeffe, Terence. AU - Joseph, Bellal. PY - 2015/4/4. Y1 - 2015/4/4. N2 - BACKGROUND: The practice of transfusing ones own shed whole blood has obvious benefits such as reducing the need for allogeneic transfusions and decreasing the need for other fluids that are typically used for resuscitation in trauma. It is not widely adopted in the trauma setting because of the concern of worsening coagulopathy and the inflammatory process. The aim of this study was to assess outcomes in trauma patients receiving whole blood autotransfusion (AT) from hemothorax. METHODS: This is a multi-institutional retrospective study of all trauma patients who received autologous whole blood transfusion from hemothorax ...
No doubt that PVCR is a very effective procedure for the correction of rigid deformities. It gives the surgeon freedom of manipulation after 360-degree release. But at the same time it is technically very demanding, lengthy and not without complications. It is one of the lengthiest and most tiring surgeries with reported mean operative time of more than 4 hours, and average blood loss of above 2000ml.13,15 This requires teamwork and great efforts from surgical and anaesthesia staff. One of the greatest concerns of a spine surgeon is new onset neurological deficit, which is not very uncommon in these patients. One study reported 3.4% occurrence of new neurological deficit in 321 patients with severe deformities treated with either PSO or PVCR.20 Patients were monitored during surgery with somatosensory-evoked potentials and Stagnara wake-up test. The high risk for new neurological deficit was pre-existing neurological deficit. A study reported the incidence of complications in 152 patients in ...
When used as the sole source of transfused blood, the principal advantage of autologous blood transfusion is the avoidance of transmission of infectious agents and the avoidance of the purported adverse immunomodulatory effects of allogeneic transfusion. In the 1990s, however, the risks of transfusion-transmitted diseases have been greatly reduced, and estimates of the cost-effectiveness of pre-operative autologous blood donations now vary between 2470 dollars and 3,400,000 dollars per quality-adjusted year of life saved, depending on assumptions about the existence and magnitude of any adverse immunomodulatory effects of allogeneic transfusion. There is a paucity of randomized controlled trials evaluating the clinical outcomes and the cost-effectiveness of autologous transfusion procedures, and this situation is unlikely to change in the near future because of the difficulties in conducting such trials. Read More ...
... - Book Information By: Petra Seeber and Aryeh Shander Commended in the Haematology category at the British Medical Association Book Awards 2008 This unique and practical book introduces the reader to the concept of blood management and explains how to improve patient outcomes by avoiding undue blood loss, enhancing the patients own blood, effective management of anemia and coagulopathy. Basics of Blood Management is the first book dedicated to blood
A new <"http://www.yourlawyer.com/topics/overview/trasylol">Trasylol study is shedding more light on possible reasons behind the drug’s higher-than normal death rate. According to British researchers, while use of the clotting drug aprotininâ€"known as Trasylolâ€"appears safe during on-pump cardiac surgeries, it appears that combining it with angiotensin-converting enzyme inhibitorsâ€"or ACE inhibitorsâ€"during off-pump cardiac surgeries shows a significant risk of post-operative kidney dysfunction. Researchers analyzed 9,875 cardiac surgery patients, most of who (5,434) had on-pump cardiac surgery, meaning their hearts were stopped and they were hooked up to a heart-bypass machine during surgery. The other patients had off-pump cardiac surgery, in which surgeons operated on their beating hearts.. Trasylol is used to reduce perioperative blood loss and the need for blood transfusion in those patients undergoing cardiopulmonary bypass during coronary artery bypass graft ...
The global Autotransfusion Systems Market is poised to reach USD 505 million by 2024. Autotransfusion Products Market Report provides crucial industry insights that will help your business grow.
November 1, 2007 - Redsense Medicals blood loss detection device for monitoring venous needle dislodgement has been granted FDA approval, and is now available for sale in the United States. The Swedish company says the device has already been granted CE approval. With the FDAs approval, the maker says Redsense is the first clinically tested, reliable blood loss monitoring system available in the U.S.. About 1.5 million patients worldwide receive more than 200 million dialysis treatments every year. The size of the market is forecast to increase due to an aging population and the rise of diseases such as diabetes type II. Medical professionals have long been aware of the risk of venous needle dislodgement during dialysis treatment.. Until now, the typical method of needle dislodgement detection for this common form of renal therapy has been venous pressure monitoring, a built-in function of all dialysis machines. However, incidents have been reported whereby significant blood loss occurred ...
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To support our Vision of a Total Healing Environment, Yavapai Regional Medical Center (YRMC) wants you to be informed about your healthcare. We also want to partner with you to help you make decisions about the care you receive. This includes presenting you with treatment options and helping you understand the availability of alternatives to blood transfusions.. Blood transfusions have been an important life-saving therapy for many years. What is frequently overlooked, however, is the fact that a therapy deemed suitable yesterday may no longer be the first choice today. While blood transfusions continue to be important to healthcare delivery, growing evidence shows that patients who do not receive a transfusion have lower infection rates as well as fewer kidney, lung and heart complications. This is the science behind Patient Blood Management (PBM) and the reason why YRMC has made the commitment to adopt comprehensive PBM protocols for patients who prefer to not receive a transfusion. ...
The early administration of tranexamic acid (TXA) to bleeding trauma patients reduces all-cause mortality without increasing the risk of vascular occlusive events. Indeed, the risk of arterial thrombosis appears to be reduced with TXA. In this commentary we hypothesize that TXA has an antithrombotic effect and explore potential mechanisms. These include inhibition of the inflammatory effects of plasmin, effects on platelets and effects on factors V and VIII. If proven, these antithrombotic effects would have major implications for the systemic use of TXA in surgical patients, where TXA has been clearly shown to reduce bleeding.
LYSTEDA (Tranexamic acid) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
Detecting an iron deficiency or discovering hidden blood loss is a reason to get iron blood test results. Most iron deficiencies are due to blood loss, while a much smaller amount is due to nutritional inadequacies or malabsorption.
Apparatus and methods for identifying and counting objects having identifiers entering and exiting a surgical field are provided. In one embodiment, the apparatus has an entry scanner, a hand held scanner and an exit scanner for generating a detection field and for receiving data which identifies said objects. In another embodiment, the apparatus has a plurality of lower antennas and an upper antenna for generating a detection field and for receiving data which identifies said objects. Various surgical devices with identifiers and methods for preventing electromagnetic coupling between and protecting objects and identifiers are also provided. The invention further provides apparatus and methods comprising a handheld scanner and a mat adapted to underlie a patient during a surgical procedure.
Uncontrollable blood loss is a leading cause of death on the battlefield and the operating table alike. Researchers at the Feinstein have developed the neural tourniquet, a bioelectronic medical device that uses electronic nerve stimulation to slow blood loss. They have found that using as little as 60 seconds of electrical stimulation to neural pathways to the spleen is sufficient to prepare the body for clotting in the event of a wound. By priming the bodys coagulation system, it is able to clot 50 percent more rapidly and reduce the volume of blood loss by 50 percent. The neural tourniquet is applicable to a range of life-saving scenarios: to the more than 50 million planned surgeries taking place in America each year; to accident scenes where first responders treat bleeding trauma victims; and on the battlefield treating the blood loss of wounded service men and women. To bring the neural tourniquet to market, the Feinstein has partnered with Battelle, a leading non-profit scientific ...
Many institutions that have made this step suggest that viscoelastic (VE) testing may be one of your patient blood management tools.
CATSmart Continuous Autotransfusion System-Fresenius Kabi https://www.catsmart.us. The CATSmart Continuous Autotransfusion System is the only continuous autotransfusion system working on the principle of the continuous flow centrifuge. CATSmart technology is simple to operate, has high PRC Quality, and is engineered to fit into your OR and the way you work. Ref: 0101 CATSM-01-12/19 ...
This is Annes husband, Brian, and I hope Im doing this correctly. Annes surgery was today (Tuesday). Shes stable, but there was significant blood loss as she required 8 pints. Due to the blood loss, Dr. Lonner needed to shorten the surgery somewhat (if you call 8 hours short) so he couldnt do everything he had hoped. There is significant curve correction though, and well see where we go once we figure out the cause of the blood loss. Anne wasnt taking any blood thinning
Buy Travatan Online Cash On Delivery, Cheap Travatan C.O.D Tranexamic Acid Order No Membership Overnight, Cheap Tranexamic Acid Overnight Delivery Cheap Sotalol ...
Система для реинфузии аутологичной эритроцитарной массы АutoLog собирает и обрабатывает кровь из операционной раны, в результате чего формируется отмытая эритроцитарная масса для последующего введения пациенту ...
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership. Click Here to Learn More ...
TY - JOUR. T1 - The effect of tranexamic acid on hemoglobin levels during total knee arthroplasty. AU - Pachauri, Amit. AU - Acharya, Kiran K.. AU - Tiwari, Akhilesh Kumar. PY - 2014/1/1. Y1 - 2014/1/1. N2 - The aim of this study was to evaluate the efficacy of perioperative administration of 1,4-aminocarboxylic acid (tranexamic acid) in reducing the intraoperative and postoperative blood loss in patients undergoing total knee replacement (TKR). Tranexamic acid is an antifibrinolytic agent that is 7-10 times as potent as epsilon aminocaproic acid. We had investigated the effect of tranexamic acid on blood loss intraoperatively and postoperatively during and after TKR thereby significantly preventing a decrease in postop Hb in these patients. This study was a randomized, prospective, observational, double-blinded study on 99 patients, after obtaining ethical committee approval and valid informed consent from patients to be part of the study. In the study group, the drug was administered in 2 ...
Looking for Aminocaproic acid? Find out information about Aminocaproic acid. 1. any substance that dissociates in water to yield a sour corrosive solution containing hydrogen ions, having a pH of less than 7, and turning litmus red... Explanation of Aminocaproic acid
Free download. Book file PDF easily for everyone and every device. You can download and read online Haemostasis in Cerebrospinal Fluid: Basic Concept of Antifibrinolytic Therapy of Subarachnoid Haemorrhage (Acta Neurochirurgica Supplement) file PDF Book only if you are registered here. And also you can download or read online all Book PDF file that related with Haemostasis in Cerebrospinal Fluid: Basic Concept of Antifibrinolytic Therapy of Subarachnoid Haemorrhage (Acta Neurochirurgica Supplement) book. Happy reading Haemostasis in Cerebrospinal Fluid: Basic Concept of Antifibrinolytic Therapy of Subarachnoid Haemorrhage (Acta Neurochirurgica Supplement) Bookeveryone. Download file Free Book PDF Haemostasis in Cerebrospinal Fluid: Basic Concept of Antifibrinolytic Therapy of Subarachnoid Haemorrhage (Acta Neurochirurgica Supplement) at Complete PDF Library. This Book have some digital formats such us :paperbook, ebook, kindle, epub, fb2 and another formats. Here is The CompletePDF Book Library. ...
Objective To study the effects of complete laparoscopic common bile duct exploration on elderly patients with complicated hepatolithiasis and their inflammatory stress response index and immune function.Methods 64 cases of the elderly patients( over 60 years old) diagnosed with complicated hepatolithiasis in our hospital were selected and randomly divided into two groups. 32 cases of patients treated with complete laparoscopic common bile duct exploration was enrolled in the laparoscopic group,and the other 32 cases treated with traditional open surgery were classified as the open group. The curative effects of the two groups were compared. Results The operation time,intra-operative blood loss,postoperative anal exhaust time,hospital stays and medical costs in the laparoscopic group were shorter or less than those in the open group( P 0. 05). The levels of total bilirubin,direct bilirubin and indirect bilirubin of two groups one month after the operation were significantly decreased( P 0. 05),and the
OBJECTIVE: To compare the efficiency and safety of the transperitoneal approaches with retroperitoneal approaches in laparoscopic partial nephrectomy for renal cell carcinoma and provide evidence-based medicine support for clinical treatment. METHODS: A systematic computer search of PUBMED, EMBASE, and the Cochrane Library was executed to identify retrospective observational and prospective randomized controlled trials studies that compared the outcomes of the two approaches in laparoscopic partial nephrectomy. Two reviewers independently screened, extracted, and evaluated the included studies and executed statistical analysis by using software STATA 12.0. Outcomes of interest included perioperative and postoperative variables, surgical complications and oncological variables. RESULTS: There were 8 studies assessed transperitoneal laparoscopic partial nephrectomy (TLPN) versus retroperitoneal laparoscopic partial nephrectomy (RLPN) were included. RLPN had a shorter operating time (SMD = ...

Tranexamic acid - WikipediaTranexamic acid - Wikipedia

... meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss". The British Journal of Surgery. 100 ... In surgical corrections of craniosynostosis in children it reduces the need for blood transfusions. In spinal surgery (e.g., ... It is of proven value in clearing the field of surgery and reducing blood loss when given before or after surgery. Drain and ... Tranexamic acid is used for a short period of time before and after the surgery to prevent major blood loss and decrease the ...
more infohttps://en.wikipedia.org/wiki/Tranexamic_acid

Da Vinci Robotic Surgery | WMofNiagaraDa Vinci Robotic Surgery | WMofNiagara

2)Less blood loss. 3)Fewer complications. 4)Less scarring. 5)A shorter hospital stay. 6)A faster return to normal daily ... 2012 Intuitive Surgical. All rights reserved. Intuitive, Intuitive Surgical, da Vinci, da Vinci S, da Vinci Si, Single-Site, ... Surgical techniques: robot-assisted laparoscopic hysterectomy with the da Vinci surgical system. Int J Med Robot. 2006 Dec;2(4 ... Senapati S, Advincula A. Surgical techniques: robot-assisted laparoscopic Myomectomy with the da Vinci® surgical system. J ...
more infohttp://www.wmniagara.com/da-vinci-robotic-surgery/

Jehovahs Witnesses and Blood  - Tens of Thousands Dead in Hidden Tragedy | AJWRB.orgJehovah's Witnesses and Blood - Tens of Thousands Dead in Hidden Tragedy | AJWRB.org

A trauma or childbirth death due to blood loss, when that life could have been saved by a transfusion, is still a life lost. ... 1. Are transfusions overrated? Surgical outcome of Jehovahs Witnesses. Kitchens CS. The American Journal of Medicine. 1993 Feb ... Physicians are well informed about the risks of using blood products, including all of the blood products (100% of blood in ... The blood supply is safe, and rejecting a medically necessary blood transfusion on the basis that there are few post surgery ...
more infohttp://ajwrb.org/jehovahs-witnesses-and-blood-tens-of-thousands-dead-in-hidden-tragedy?replytocom=1783

Gauss Surgical Blood Loss Measurement App Approved by FDA for Use in ORs | MedgadgetGauss Surgical Blood Loss Measurement App Approved by FDA for Use in ORs | Medgadget

Its a crude guess in many surgical cases. Blood gets soaked in laps, sponges, and drapes. But ... or estimated blood loss, is estimated for a reason. ... Gauss Surgical Blood Loss Measurement App Approved by FDA for ... EBL, or estimated blood loss, is "estimated" for a reason. Its a crude guess in many surgical cases. Blood gets soaked in laps ... Press release: Gauss Surgical Announces FDA Approval of First Mobile Platform for Real-Time Estimation of Surgical Blood Loss… ...
more infohttps://www.medgadget.com/2014/05/gauss-surgical-blood-loss-measurement-app-approved-by-fda-for-use-in-ors.html

Comparison of serum markers for muscle damage, surgical blood loss, postoperative recovery, and surgical site pain after...Comparison of serum markers for muscle damage, surgical blood loss, postoperative recovery, and surgical site pain after...

Intraoperative blood loss (51 ± 41 ml in the XLIF/PPS group and 206 ± 191 ml in the PLIF group), postoperative WBC counts and ... The XLIF/PPS procedure is advantageous to minimize blood loss and muscle damage, with consequent earlier recovery of daily ... We analyzed postoperative serum makers for muscle damage and inflammation, postoperative surgical pain, and performance status ... Comparison of serum markers for muscle damage, surgical blood loss, postoperative recovery, and surgical site pain after ...
more infohttps://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-017-1775-y

1.5 Million Settlement Over Surgical Errors Resulting in Massive Blood Loss and Amputation of the Foot1.5 Million Settlement Over Surgical Errors Resulting in Massive Blood Loss and Amputation of the Foot

... Sommers Schwartz ... During the operation, injury was done to the patients iliac veins, causing a 20-liter blood loss. The extensive hemorrhage ... The 74-year-old widowed plaintiff sought damages for the pain and suffering, permanent disfigurement, and economic loss caused ... 1.5 million settlement on behalf of a woman who was severely harmed as a result of surgical errors. The plaintiff underwent a ...
more infohttps://www.sommerspc.com/verdicts/1-5-million-settlement-surgical-errors-resulting-massive-blood-loss-amputation-foot/

Gauss Surgical Announces FDA 510(k) Clearance of Triton Canister App for Accurate Surgical Blood Loss Monitoring - Gauss...Gauss Surgical Announces FDA 510(k) Clearance of Triton Canister App for Accurate Surgical Blood Loss Monitoring - Gauss...

Now, in addition to estimating blood loss on surgical sponges, the system can accurately estimate blood loss in blood bearing ... canisters, giving clinicians a better picture of overall surgical blood loss. ... Gauss Surgical today announced that the company has received U.S. Food and Drug Administration (FDA) 510(k) clearance for its ... Now, in addition to estimating blood loss on surgical sponges, the system can accurately estimate blood loss in blood bearing ...
more infohttp://www.gausssurgical.com/news-1/2017/6/18/gauss-surgical-announces-fda-510k-clearance-of-triton-canister-app-for-accurate-surgical-blood-loss-monitoring

Ellegaard Newsletter Spring 2013 by Burchardt Reklame AS - IssuuEllegaard Newsletter Spring 2013 by Burchardt Reklame AS - Issuu

by surgical blood loss. The latter is easily quantified:. Hypothermia is more appropriately prevented than treated. Nu- ... The net loss of circulating blood volume over time will result in ... The volume of blood lost to surgical suction in suction jars ... Areas of diffuse atalectic lung fails to oxygenate blood and by increasing venous admixture will lower blood O2 levels. The ... mLs blood lost = (PCV in suction jar / pig PCV) X mls blood in ... 11) Fluid and blood loss management. nervous depression and so ...
more infohttps://issuu.com/burchardt-reklame/docs/ellegaard-newsletter-39?mode=window&viewMode=doublePage

Articles by A.A. Chan, PhD : Anesthesia & AnalgesiaArticles by A.A. Chan, PhD : Anesthesia & Analgesia

ACUTE NORMOVOLEMIC HEMODILUTION: ALLOWABLE LIMITS ON SURGICAL BLOOD LOSS AND ON HEMOGLOBIN CONCENTRATION. Chan, A.A.; Loubser, ...
more infohttps://journals.lww.com/anesthesia-analgesia/pages/author.aspx?firstName=A.A.&lastName=Chan

Health information and publications in Africa African Index Medicus DatabaseHealth information and publications in Africa African Index Medicus Database

... and to determine the effect of surgical time on blood loss. Patients and Methods: A prospective study of blood loss after total ... and to determine the effect of surgical time on blood loss. Patients and Methods: A prospective study of blood loss after total ... 2 result(s) search for keyword(s) Blood Loss, Surgical Add the result to your basket Refine your search Generate the RSS feed ... surgical time 2 h), and the effect of these on blood loss was evaluated. Results: The mean intra- and post-operative blood ...
more infohttp://indexmedicus.afro.who.int/aim/opac_css/index.php?lvl=more_results&mode=keyword&user_query=Blood+Loss%2C+Surgical&tags=ok

Observational Cohort Study of TachoSil (TC-018-IN) - Full Text View - ClinicalTrials.govObservational Cohort Study of TachoSil (TC-018-IN) - Full Text View - ClinicalTrials.gov

Blood Loss, Surgical Drug: Fibrinogen (human) + thrombin (human) (TachoSil) Phase 4 Study Design ...
more infohttps://clinicaltrials.gov/ct2/show/NCT00285623

Search of: Recruiting, Not yet recruiting, Available Studies | Senior - List Results - ClinicalTrials.govSearch of: Recruiting, Not yet recruiting, Available Studies | Senior - List Results - ClinicalTrials.gov

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture. *Blood Loss, Surgical ... loss of weight. 1886. All. 70 Years and older (Senior). NCT03390816. 2017-A01397-46. NutriAgeCancer. November 2, 2017. December ... Blood pressure response rate. *Change from baseline in the differences in standing SBP and DBP compared to their sitting ... Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders. *Age Problem ...
more infohttps://clinicaltrials.gov/ct2/results?recr=Open&age=2&show_flds=Y

Salvage Use of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery - Full Text View -...'Salvage Use' of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery - Full Text View -...

Cardiac surgical procedures. Surgical blood loss. Surgical haemostasis. Factor VIIa. Anaesthesia. Additional relevant MeSH ... ICU Management Blood loss measurement in the closed drainage system must be documented at least once hourly, or more frequently ... At the discretion of treating physicians if the proposed transfusion protocol post CPB is inadequate to keep up with blood loss ... Postoperative transfusion according to established ICU protocol Blood loss , 250mL/hr NOTIFY SURGEON (CONSIDER RETURN TO ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT00214656

Postoperative Care Flashcards by Rebecca Abelman | BrainscapePostoperative Care Flashcards by Rebecca Abelman | Brainscape

How do you replace surgical blood loss? Replace in a 3:1 ratio with IVF ... Replace blood lost during surgery + provide maintenance IVF + make up for fluid loss in drains/NG tubes/fistulas ... Every 3 Na over 140 indicates 1 L of water loss, presents as volume depletion (slow) or altered MS (rapid); give D5 1/2 NS to ... Infected thrombus at site of venipuncture; Tx is to remove catheter and surgical excision of infected vein to the first non- ...
more infohttps://www.brainscape.com/flashcards/postoperative-care-3612511/packs/5514398

Minimally Invasive Surgical Treatments Available at the UPMC Passavant Spine CenterMinimally Invasive Surgical Treatments Available at the UPMC Passavant Spine Center

Reduced surgical blood loss *Reduced use of post-op narcotic pain medicines ... Minimally Invasive Surgical Spine Care. The spine surgeons at UPMC Passavant utilize the latest, minimally invasive surgery ...
more infohttps://www.upmc.com/locations/hospitals/passavant/services/spine/miminally-invasive

Análise da coagulação sanguínea com a administração profilática da desmopressina...Análise da coagulação sanguínea com a administração profilática da desmopressina...

Blood coagulation. Blood loss surgical. Blood transfusion. Cardiac surgery. Hemostatics. Postoperative complications. ... blood flow through surgical drains and the consumption of blood components within 48 hours. Results: Blood levels of Factor ... Flow rate of surgical drains, blood balance and consumption of blood components did not present significant differences between ... Blood samples were collected at three different times in all study participants. Blood coagulation and perioperative bleeding ...
more infohttp://www.teses.usp.br/teses/disponiveis/5/5152/tde-08052018-124047/fr.php

The role of perioperative warming in surgery: a systematic reviewThe role of perioperative warming in surgery: a systematic review

Keywords : Body temperature regulation; Hypothermia; Blood loss, surgical; Shivering; Wound infection. · abstract in Portuguese ... Systemic warming of the surgical patient is also associated with less perioperative blood loss through preventing hypothermia- ... Both in the random and the fixed effect models, the warming group was associated with significantly less blood loss. However, ... CONCLUSION: Perioperative warming of surgical patients is effective in reducing postoperative wound pain, wound infection and ...
more infohttp://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-31802009000400009&lng=en&nrm=iso&tlng=en

February 2018 - Volume 126 - Issue 2 - Contributor Index : Anesthesia & AnalgesiaFebruary 2018 - Volume 126 - Issue 2 - Contributor Index : Anesthesia & Analgesia

In Vitro Evaluation of a Novel Image Processing Device to Estimate Surgical Blood Loss in Suction Canisters. Konig, Gerhardt; ...
more infohttps://journals.lww.com/anesthesia-analgesia/Pages/contributorindex.aspx?filter=H

Tranexamic Acid in Surgery of Advanced Ovarian CancerTranexamic Acid in Surgery of Advanced Ovarian Cancer

Surgical blood loss. *Postoperative blood loss. *Preventive therapy. *Thromboembolism. *Ovarian Neoplasms. .map{width:100%; ...
more infohttp://www.knowcancer.com/cancer-trials/NCT00740116/

Important surgical measures and techniques at cesarean hysterectomy for placenta previa accreta.Important surgical measures and techniques at cesarean hysterectomy for placenta previa accreta.

Blood Loss, Surgical / prevention & control. Catheterization / statistics & numerical data. Cesarean Section / methods*, ... Hemostasis, Surgical / methods. Humans. Hysterectomy / methods*, statistics & numerical data. Placenta Accreta / epidemiology ...
more infohttp://www.biomedsearch.com/nih/Important-surgical-measures-techniques-at/23323568.html

Cervical Disc Replacement SurgeryCervical Disc Replacement Surgery

Less surgical blood loss. If you have been suffering from neck or back pain, and conservative treatments have not provided ... This can result in a loss of flexibility. This type of traditional open neck disc surgery carries a number of risks, including ...
more infohttps://www.laserspineinstitute.com/back_problems/disc_surgery/types/cervicalreplacement/

Spine Stabilization with Bone Grafts | Laser Spine Institute | Laser Spine InstituteSpine Stabilization with Bone Grafts | Laser Spine Institute | Laser Spine Institute

Less surgical blood loss. *Be up and walking within a few hours of surgery^ ... Home » Been to Doctors » Surgical .edit-btn-container img { width: auto; } How are bone grafts used to stabilize the spine? ...
more infohttps://www.laserspineinstitute.com/beendoctors/section/surgical/29/graft/281/

Patent US5107862 - Surgical implement detector utilizing a powered marker - Google PatentsPatent US5107862 - Surgical implement detector utilizing a powered marker - Google Patents

A battery powered marker is secured to a surgical implement positioned within the wound. Field generating means are provided ... An apparatus for detecting a surgical implement in human or animal tissue has means for defining a transmitting zone ... Surgical Resources, L.L.C.. Automatic surgical sponge counter and blood loss determination system. ... Surgical Resources, L.L.C.. Automatic surgical sponge counter and blood loss determination system. ...
more infohttp://www.google.com/patents/US5107862?dq=6981235

Patent US20050217904 - Container with built-in weighing device - Google PatentsPatent US20050217904 - Container with built-in weighing device - Google Patents

Surgical Resources, L.L.C.. Automatic surgical sponge counter and blood loss determination system. ... Surgical sponge counter and blood loss determination system. US4696360 *. 11 Aug 1986. 29 Sep 1987. Manny Homen. Weighing ... Surgical sponge collector with means for counting and weighing sponges. US3836755 *. 12 Feb 1973. 17 Sep 1974. Gretag Ag. Self- ...
more infohttp://www.google.com.au/patents/US20050217904
  • Tranexamic acid is used to prevent and treat blood loss in a variety of situations, such as dental procedures for hemophiliacs, heavy menstrual bleeding, and surgeries with high risk of blood loss. (wikipedia.org)
  • Gauss Surgical (Los Altos, CA) just received FDA approval for its Triton Fluid Management System, an iPad app that estimates, via a proprietary algorithm, blood loss in surgical sponges just by looking at them. (medgadget.com)
  • Los Altos, Calif., March 16, 2015 - Gauss Surgical today announced that the company has received U.S. Food and Drug Administration (FDA) 510(k) clearance for its Triton Canister App, the second core product in its Triton System™ portfolio, the world's first and only mobile platform for real-time monitoring of surgical blood loss. (gausssurgical.com)
  • Our challenge was to develop a highly accurate solution while preserving the simplicity that is critical to our users' experience in the operating room," said Siddarth Satish, Founder and Chief Technology Officer of Gauss Surgical. (gausssurgical.com)
  • With this FDA clearance, we have extended the Triton System's ability to give clinicians a better assessment of overall blood loss during surgery," said Milton B. McColl, M.D., Chief Executive Officer of Gauss Surgical. (gausssurgical.com)
  • An apparatus for detecting a surgical implement in human or animal tissue has means for defining a transmitting zone encompassing a surgical wound in the tissue. (google.com)
  • A battery powered marker is secured to a surgical implement positioned within the wound. (google.com)
  • Using the iPad camera, the system captures snapshots of surgical canisters and sends the images to the cloud where sophisticated algorithms estimate the hemoglobin content and the blood loss regardless of confounding factors such as saline/irrigation fluid, ambient lighting variations, and hemolysis (red cell rupture). (gausssurgical.com)
  • Products in the Triton System portfolio feature an intuitive iPad interface, require minimal training, and seamlessly integrate into existing surgical workflow. (gausssurgical.com)
  • Sommers Schwartz attorney Kenneth Watkins secured a confidential $1.5 million settlement on behalf of a woman who was severely harmed as a result of surgical errors . (sommerspc.com)
  • We believe that providing more accurate estimates aids in clinical decision making, particularly regarding the use of blood products. (gausssurgical.com)
  • Both in the random and the fixed effect models, the warming group was associated with significantly less blood loss. (scielo.br)
  • These showed a strong positive correlation with total blood loss (r = 0.790, P (who.int)
  • Blood samples were collected at three different times in all study participants. (usp.br)
  • The app sends the photo to a cloud server for image processing, which in turn sends back an estimate of the amount of blood in the wet sponge. (medgadget.com)