Light: That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.Models, Neurological: Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Synapses: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Amplifiers, Electronic: Electronic devices that increase the magnitude of a signal's power level or current.Electric Power Supplies: Devices that control the supply of electric current for running electrical equipment.Electricity: The physical effects involving the presence of electric charges at rest and in motion.Blinking: Brief closing of the eyelids by involuntary normal periodic closing, as a protective measure, or by voluntary action.Body Temperature: The measure of the level of heat of a human or animal.Eyelids: Each of the upper and lower folds of SKIN which cover the EYE when closed.Body Temperature Regulation: The processes of heating and cooling that an organism uses to control its temperature.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Photography: Method of making images on a sensitized surface by exposure to light or other radiant energy.Photography, Dental: Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.Pathology, Surgical: A field of anatomical pathology in which living tissue is surgically removed for the purpose of diagnosis and treatment.Online Systems: Systems where the input data enter the computer directly from the point of origin (usually a terminal or workstation) and/or in which output data are transmitted directly to that terminal point of origin. (Sippl, Computer Dictionary, 4th ed)Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.RestaurantsMenu PlanningBooksConcentration Camps: Facilities in which WARFARE or political prisoners are confined.Democratic People's Republic of Korea: A country located on the Korean Peninsula whose capital is Pyongyang. The country was established September 9, 1948.Sparganum: The larval form of the diphyllobothriid tapeworms of the genus DIPHYLLOBOTHRIUM and SPIROMETRA. Fish-eating mammals and man are the final hosts.Whistleblowing: The reporting of observed or suspected PROFESSIONAL MISCONDUCT or incompetence to appropriate authorities or to the public.Korea: Former kingdom, located on Korea Peninsula between Sea of Japan and Yellow Sea on east coast of Asia. In 1948, the kingdom ceased and two independent countries were formed, divided by the 38th parallel.Republic of Korea: The capital is Seoul. The country, established September 9, 1948, is located on the southern part of the Korean Peninsula. Its northern border is shared with the Democratic People's Republic of Korea.Eyelashes: The hairs which project from the edges of the EYELIDS.Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)Eye Injuries: Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)Eye Foreign Bodies: Inanimate objects that become enclosed in the eye.Alicyclobacillus: A genus of GRAM-POSITIVE ENDOSPORE-FORMING RODS, in the family Alicyclobacillaceae, containing a unique lipid in their membranes.Electrophoresis, Microchip: A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.Microchip Analytical Procedures: The preparation and analysis of samples on miniaturized devices.Hebrides: A group of islands in the Atlantic Ocean west of Scotland, comprising the Outer Hebrides and the Inner Hebrides.Cyclonic Storms: Non-frontal low-pressure systems over tropical or sub-tropical waters with organized convection and definite pattern of surface wind circulation.Color: The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.Unedited FootageDarkness: The absence of light.Color Perception: Mental processing of chromatic signals (COLOR VISION) from the eye by the VISUAL CORTEX where they are converted into symbolic representations. Color perception involves numerous neurons, and is influenced not only by the distribution of wavelengths from the viewed object, but also by its background color and brightness contrast at its boundary.Videotape Recording: Recording of visual and sometimes sound signals on magnetic tape.Tears: The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.Ophthalmic Solutions: Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.Mouth Protectors: Devices or pieces of equipment placed in or around the mouth or attached to instruments to protect the external or internal tissues of the mouth and the teeth.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Firefly Luciferin: A benzothaizole which is oxidized by LUCIFERASES, FIREFLY to cause emission of light (LUMINESCENCE).Photobiology: The branch of biology dealing with the effect of light on organisms.Photic Stimulation: Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.Head: The upper part of the human body, or the front or upper part of the body of an animal, typically separated from the rest of the body by a neck, and containing the brain, mouth, and sense organs.Eye Movements: Voluntary or reflex-controlled movements of the eye.Eye Diseases: Diseases affecting the eye.Preservatives, Pharmaceutical: Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)Literature, ModernWit and Humor as Topic: The faculty of expressing the amusing, clever, or comical or the keen perception and cleverly apt expression of connections between ideas that awaken amusement and pleasure. (From Random House Unabridged Dictionary, 2d ed)Mite Infestations: Infestations with arthropods of the subclass ACARI, superorder Acariformes.Eyeglasses: A pair of ophthalmic lenses in a frame or mounting which is supported by the nose and ears. The purpose is to aid or improve vision. It does not include goggles or nonprescription sun glasses for which EYE PROTECTIVE DEVICES is available.Refractive Errors: Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.Open Reading Frames: A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).Quantum Dots: Nanometer sized fragments of semiconductor crystalline material which emit PHOTONS. The wavelength is based on the quantum confinement size of the dot. They can be embedded in MICROBEADS for high throughput ANALYTICAL CHEMISTRY TECHNIQUES.Semiconductors: Materials that have a limited and usually variable electrical conductivity. They are particularly useful for the production of solid-state electronic devices.Cadmium Compounds: Inorganic compounds that contain cadmium as an integral part of the molecule.Selenium Compounds: Inorganic compounds that contain selenium as an integral part of the molecule.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Enema: A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.Music: Sound that expresses emotion through rhythm, melody, and harmony.Malus: A plant genus in the family ROSACEAE, order Rosales, subclass Rosidae. It is best known as a source of the edible fruit (apple) and is cultivated in temperate climates worldwide.Music Therapy: The use of music as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.Erwinia amylovora: A species of gram-negative bacteria, in the genus ERWINIA, causing a necrotic disease of plants.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Fiber Optic Technology: The technology of transmitting light over long distances through strands of glass or other transparent material.Calcium Channels: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.Quadriplegia: Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.Opsoclonus-Myoclonus Syndrome: A neurological condition that is characterized by uncontrolled rapid irregular movements of the eye (OPSOCLONUS) and the muscle (MYOCLONUS) causing unsteady, trembling gait. It is also known as dancing eyes-dancing feet syndrome and is often associated with neoplasms, viral infections, or autoimmune disorders involving the nervous system.Persistent Vegetative State: Vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished.Communication Aids for Disabled: Equipment that provides mentally or physically disabled persons with a means of communication. The aids include display boards, typewriters, cathode ray tubes, computers, and speech synthesizers. The output of such aids includes written words, artificial speech, language signs, Morse code, and pictures.Pons: The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.PaintingsChicagoPowders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Maze Learning: Learning the correct route through a maze to obtain reinforcement. It is used for human or animal populations. (Thesaurus of Psychological Index Terms, 6th ed)Rats, Inbred BUFNevadaElectronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Hospital Bed Capacity, 100 to 299Computer Storage Devices: Devices capable of receiving data, retaining data for an indefinite or finite period of time, and supplying data upon demand.Catalogs, LibraryCatalogs as Topic: Ordered compilations of item descriptions and sufficient information to afford access to them.Software: Sequential operating programs and data which instruct the functioning of a digital computer.SwedenSyndrome: A characteristic symptom complex.Chordae Tendineae: The tendinous cords that connect each cusp of the two atrioventricular HEART VALVES to appropriate PAPILLARY MUSCLES in the HEART VENTRICLES, preventing the valves from reversing themselves when the ventricles contract.Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.Imagination: A new pattern of perceptual or ideational material derived from past experience.Viscum album: A plant species of the family VISCACEAE, order Santalales, subclass Rosidae. This is the traditional mistletoe of literature and Christmas. Members contain viscotoxin (5 kDa basic polypeptides related to thionins), beta-galactoside- and N-acetyl-D-galactosamine-specific lectin II (60 kDa), and polysaccharides. Mistletoe lectin I is a type 2 ribosome-inactivating protein. Commercial extracts include Plenosol, Eurixor, Helixor Isorel, Iscador, and NSC 635089 (ANTINEOPLASTIC AGENTS, PHYTOGENIC).Chenopodium album: A plant species in the CHENOPODIUM genus known for edible greens.Motion Pictures as Topic: The art, technique, or business of producing motion pictures for entertainment, propaganda, or instruction.

Electrical stimulation as a therapeutic option to improve eyelid function in chronic facial nerve disorders. (1/564)

PURPOSE: To establish whether it is possible to improve orbicularis oculi muscle function in the eyelids of patients with a chronic seventh cranial nerve palsy by using transcutaneous electrical stimulation to the point at which electrical stimulation induces a functional blink. METHODS: Ten subjects (one woman, nine men) aged 36 to 76 with chronic, moderate to severe facial nerve palsy were recruited into the study. Voluntary and spontaneous eyelid movements were assessed, using an optical measuring system, before, during, and after a 3-month treatment period. Voluntary and spontaneous lid velocities were also measured and compared with eyelid kinematic data in normal subjects (12 women, 18 men; age range, 22-56 years). RESULTS: Therapeutic electrical stimulation applied over 3 months produced improvement in eyelid movement (>2 mm) in 8 of 10 patients during voluntary eyelid closure. However, there was no significant improvement recorded in spontaneous blink amplitudes or peak downward-phase velocity of the upper eyelid. This regimen of stimulation failed to recover function well enough that a functional blink could be induced in the paretic eyelid by electrical stimulation. CONCLUSIONS: Electrical stimulation using transcutaneous electrical nerve stimulators units can improve voluntary eye closure, apparently because of a reduction in stiffness of eyelid mechanics, rather than an improvement of muscle function. Investigation of alternative stimulation regimens is warranted.  (+info)

Discharge profiles of abducens, accessory abducens, and orbicularis oculi motoneurons during reflex and conditioned blinks in alert cats. (2/564)

The discharge profiles of identified abducens, accessory abducens, and orbicularis oculi motoneurons have been recorded extra- and intracellularly in alert behaving cats during spontaneous, reflexively evoked, and classically conditioned eyelid responses. The movement of the upper lid and the electromyographic activity of the orbicularis oculi muscle also were recorded. Animals were conditioned by short, weak air puffs or 350-ms tones as conditioned stimuli (CS) and long, strong air puffs as unconditioned stimulus (US) using both trace and delayed conditioning paradigms. Motoneurons were identified by antidromic activation from their respective cranial nerves. Orbicularis oculi and accessory abducens motoneurons fired an early, double burst of action potentials (at 4-6 and 10-16 ms) in response to air puffs or to the electrical stimulation of the supraorbital nerve. Orbicularis oculi, but not accessory abducens, motoneurons fired in response to flash and tone presentations. Only 10-15% of recorded abducens motoneurons fired a late, weak burst after air puff, supraorbital nerve, and flash stimulations. Spontaneous fasciculations of the orbicularis oculi muscle and the activity of single orbicularis oculi motoneurons that generated them also were recorded. The activation of orbicularis oculi motoneurons during the acquisition of classically conditioned eyelid responses happened in a gradual, sequential manner. Initially, some putative excitatory synaptic potentials were observed in the time window corresponding to the CS-US interval; by the second to the fourth conditioning session, some isolated action potentials appeared that increased in number until some small movements were noticed in eyelid position traces. No accessory abducens motoneuron fired and no abducens motoneuron modified their discharge rate for conditioned eyelid responses. The firing of orbicularis oculi motoneurons was related linearly to lid velocity during reflex blinks but to lid position during conditioned responses, a fact indicating the different neural origin and coding of both types of motor commands. The power spectra of both reflex and conditioned lid responses showed a dominant peak at approximately 20 Hz. The wavy appearance of both reflex and conditioned eyelid responses was clearly the result of the high phasic activity of orbicularis oculi motor units. Orbicularis oculi motoneuron membrane potentials oscillated at approximately 20 Hz after supraorbital nerve stimulation and during other reflex and conditioned eyelid movements. The oscillation seemed to be the result of both intrinsic (spike afterhyperpolarization lasting approximately 50 ms, and late depolarizations) and extrinsic properties of the motoneuronal pool and of the circuits involved in eye blinks.  (+info)

HPLC analysis of closed, open, and reflex eye tear proteins. (3/564)

Changes in the closed, open and reflex eye tear proteins of normal subjects were compared and analysed. Tear proteins were resolved by high-performance liquid chromatography (HPLC) utilising both gel filtration (P-300 SW) and reverse-phase (C-18) columns and the HPLC fractions were further analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) under reducing and non-reducing conditions. The protein composition of the closed-eye tear was significantly different from that of the open and reflex-eye tear. Secretory IgA (sIgA) was the predominant protein in closed eye tears constituting 49% of the total protein compared to 11% in reflex tears, whereas lysozyme was the predominant protein (53%) in reflex tears. Levels of lactoferrin, lipocalin and lysozyme were relatively constant in both open and reflex tears. HPLC profiles of the closed-eye tears, upon continuous stimulation of lacrimal glands indicated that sIgA was significantly reduced whereas lactoferrin, lipocalin, and lysozyme were significantly increased. These results indicate that the tear composition upon waking attains that of the open eye within 4 to 5 minutes, and upon continuous stimulation this reflects the reflex-eye tear composition. It also indicates that mechanisms responsible for changes in concentration of constitutive and regulated tear protein with stimulus can be studied successfully using non-invasive methods to collect human tears.  (+info)

Midazolam effects on prepulse inhibition of the acoustic blink reflex. (4/564)

AIMS: The eye-blink response following sudden acoustic noise bursts is part of the startle reflex. The magnitude of the startle response can be attenuated by presentation of a weak stimulus before the 'startle-eliciting' stimulus (prepulse inhibition, PPI). PPI is a stable finding in awake humans but may be altered by anaesthetic drugs. We investigated whether the application of benzodiazepines altered the magnitude of PPI in healthy male volunteers. METHODS: In an open-label noncontrolled investigation, the effect of the benzodiazepine agonist midazolam on PPI was assessed in the absence and presence of the antagonist flumazenil. After an initial control period of 60 min three consecutive periods, each of 60 min, with progressively increasing concentrations of midazolam were studied (0. 02, 0.06, 0.14 mg kg-1 h-1 ). A final 60 min period during the administration of flumazenil (0.004 mg kg-1 h-1 ) and while the agonist was still present was also studied. Drug was administered intravenuously as a combination of bolus, 50% of total dose and continuous infusion over the 60 min period. Electromyographic (EMG) response of the right orbicularis oculi muscle was used to assess the startle response to noise bursts of 50 ms duration (95 dB(A)). Noise bursts were randomly preceded by nonstartling prepulses (800 Hz sinus, 50 ms duration, 65 dB(A), prepulse to noise interval 120 ms). The magnitude of PPI was calculated by dividing the EMG response to nonprepulsed stimuli by the response to prepulsed stimuli for each individual and period. Eleven subjects participated in the study, two of them were excluded from the statistical analysis because startle responses could not be reliably elicited (final sample size n=9). RESULTS: The magnitude of PPI was inversely related to the concentration of midazolam. This relationship was described by a sigmoidal Emax model, giving an Emax of 0.65+/-0.13, an ED50 of 33.9+/-10.9 ng ml-1 and gamma of 3.5+/-1.0. During infusion of flumazenil and in the presence of midazolam, the magnitude of PPI increased by 0.11 (95% CI, 0-0.22, P+info)

Effects of paired and unpaired eye-blink conditioning on Purkinje cell morphology. (5/564)

This experiment addressed (1) the importance of conjunctive stimulus presentation for morphological plasticity of cerebellar Purkinje cells and inhibitory interneurons and (2) whether plasticity is restricted to the spiny branches of Purkinje cells, which receive parallel fiber input. These issues were investigated in naive rabbits and in rabbits that received paired or unpaired presentations of the conditioned stimulus (CS) and unconditioned stimulus (US). To direct CS input to the cerebellar cortex, pontine stimulation served as the CS. Air puffs to the cornea served as the US. Paired condition rabbits received pontine stimulation for 350 msec paired with a coterminating 100-msec air puff. Unpaired condition rabbits received the same stimuli in a pseudorandom order at 1- to 32-sec intervals. Rabbits were trained for a mean of 12 days. Naive rabbits received no treatment. In Golgi-stained Purkinje neurons in lobule HVI, total dendritic length, main branch length, total spiny branch length, and number of spiny branch arbors were all greater in the naive group than in the paired and unpaired groups, which did not differ. No differences were found between the hemispheres ipsilateral and contralateral to the trained eye. The dendritic length and number of branches for inhibitory interneurons did not differ across groups. The Purkinje cell morphological changes detected with these methods do not appear to be uniquely related to the conjunctive activation of the CS and US in the paired condition.  (+info)

Learning in Parkinson's disease: eyeblink conditioning, declarative learning, and procedural learning. (6/564)

OBJECTIVE: To assess the degree of learning ability in Parkinson's disease. METHODS: Three different learning tasks: eyeblink classical conditioning with delay and trace paradigms, the California verbal learning test (CVLT), and a serial reaction time task (SRTT) were studied in patients with Parkinson's disease and normal (control) subjects. RESULTS: In the eyeblink conditioning tasks, both patients and normal subjects showed significant learning effects without between group differences. In the CVLT, patients remembered significantly fewer words than normal subjects in both short term and long term cued recall tasks. In the SRTT, normal subjects had significantly reduced response time and error rates across blocks of repeated sequence trials, whereas patients had significantly reduced error, but not response time rates. CONCLUSION: Impairment of nigrostriatal pathways selectively affects performance in complex learning tasks that are competitive and require alertness such as the SRTT, but not in simple learning procedures such as eyeblink conditioning.  (+info)

New treatment of dry eye: the effect of calcium ointment through eyelid skin delivery. (7/564)

AIM: To demonstrate the efficacy of a petrolatum based calcium ointment applied to the lower lid skin in the management of dry eye. METHODS: In a controlled double masked study, the effects of water free petrolatum ointment containing calcium carbonate (10% w/w) on tear functional factors and ocular surface vital staining in dry eye patients were observed. Petrolatum without calcium carbonate served as control. Patients were instructed to place ointment to the lower lid skin twice a day. Evaluation of subjective complaints, fluorescein and rose bengal staining patterns, blink rate, tear evaporation and tear break up time (BUT) were performed before and 3 months after treatment. In order to demonstrate the movement of petrolatum from the skin to the tear film, petrolatum containing 1% sodium fluorescein was placed on the lower lid of four healthy volunteers, and the concentration of fluorescein in the tear film was followed up to 6 hours using an anterior fluorometer. RESULTS: Subjective symptoms significantly improved in both the calcium group (p=0.001) and control (p=0.012), while only the calcium group demonstrated a significant improvement in fluorescein (p=0.043), rose bengal (p=0.021) scores, and blink rate (p=0.004). Tear evaporation also significantly decreased in both the calcium group (p=0.0004) and control (0.043). BUT did not improve in either group. CONCLUSION: Petrolatum based calcium ointment significantly improved symptoms, tear dynamics, and ocular surface staining in dry eye patients. However, some of the therapeutic effects may be due to lipids in the petrolatum vehicle. Petrolatum applied to the lower lid skin is an effective drug delivery system for slowly releasing drugs to the ocular surface.  (+info)

Impaired eye-blink conditioning in waggler, a mutant mouse with cerebellar BDNF deficiency. (8/564)

In addition to their trophic functions, neurotrophins are also implicated in synaptic modulation and learning and memory. Although gene knockout techniques have been used widely in studying the roles of neurotrophins at molecular and cellular levels, behavioral studies using neurotrophin knockouts are limited by the early-onset lethality and various sensory deficits associated with the gene knockout mice. In the present study, we found that in a spontaneous mutant mouse, waggler, the expression of brain-derived neurotrophic factor (BDNF) was selectively absent in the cerebellar granule cells. The cytoarchitecture of the waggler cerebellum appeared to be normal at the light microscope level. The mutant mice exhibited no sensory deficits to auditory stimuli or heat-induced pain. However, they were massively impaired in classic eye-blink conditioning. These results suggest that BDNF may have a role in normal cerebellar neuronal function, which, in turn, is essential for classic eye-blink conditioning.  (+info)

*Blinking

A reflex blink is not necessarily a conscious blink either; however it does happen faster than a spontaneous blink. Reflex ... Infants do not blink at the same rate of adults; in fact, infants only blink at an average rate of one or two times in a minute ... Blinking is a bodily fuction; it is a semi-autonomic rapid closing of the eyelid. A single blink is determined by the forceful ... The blinking rate is determined by the "blinking center", but it can also be affected by external stimulus. Some animals, such ...

*Menu blinking

... in Mac OS X there are no preference panes to control Menu Blinking and throughout Mac OS X the selection rectangle only blinks ... Menu Blinking is consistent in Combo Boxes but not in Drop down boxes; reasons for this are unknown. They are likely using a ... Menu blinking is user-interface affordance included in all versions of Mac OS. It is a visual effect which makes the selection ... Only in Classic Mac OSes there have been preferences for Menu Blinking where you can control how many times the selection ...

*Blinking twelve problem

The blinking twelve problem is a term used in software design. It usually refers to features in software or computer systems ... In software, 'the blinking twelve problem' thus refers to any situation in which features or functions of a program go unused ... This resulted in the default time of '12:00' blinking on the VCR display at all times of the day, which is the origin of this ...

*Blinking with Fists

... is the debut book of poetry by The Smashing Pumpkins and former Zwan frontman, Billy Corgan. The progress ... Dwight Garner (critic) of The New York Times wrote that "at its best, Blinking With Fists is vivid and angular and not much ... Four poems from Blinking with Fists at alittlepoetry.com http://billycorgan.livejournal.com/tag/poetry[permanent dead link]. ...

*International Blinking Pattern Interpretation

The International Blinking Pattern Interpretation (IBPI) is an internal computer hardware standard. It defines two items: How ... This resulted in the IBPI specification, which uses blinking frequencies of bits in the SGPIO stream to represent additional ... "International Blinking Pattern Interpretation" (PDF). SFF-8489 Specification revision 0.4. November 29, 2011. Retrieved ...

*Blunk

... is a municipality in the district of Segeberg, in Schleswig-Holstein, Germany. "Statistikamt Nord - Bevölkerung der ...

*Blinking Lights and Other Revelations

"Reviews for Blinking Lights and Other Revelations by Eels". Metacritic. Retrieved June 4, 2013. Jurek, Thom. "Blinking Lights ... "Eels: Blinking Lights and Other Revelations". Mojo (138): 95. May 2005. "Eels: Blinking Lights and Other Revelations". NME: 51 ... "Eels: Blinking Lights and Other Revelations". Q (226): 109. May 2005. Walters, Barry (June 30, 2005). "Eels: Blinking Lights ... Blinking Lights and Other Revelations is the sixth studio album by American band Eels. It was recorded over the space of 1998 ...

*Blink (community)

Blink was one of the largest online community in Norway with over 350,000 active members (7.74% of the Norwegian population). ...

*Blink element

1 blink, .blink { 2 -webkit-animation: blink 1s step-end infinite; 3 -moz-animation: blink 1s step-end infinite; 4 -o-animation ... 13 Text to blink here Or alternatively, the blink functionality can be implemented with the help of jQuery. 1 8 Text to blink ... blink 1s step-end infinite; 5 animation: blink 1s step-end infinite; 6 } 7 8 @-webkit-keyframes blink { 9 67% { opacity: 0 } 10 ... Syntax of the blink element type is identical to such standard HTML inline elements as span. For example: This text could blink ...

*Don't Blink

"Don't Blink" debuted at number 16 on the U.S. Billboard Hot Country Songs for the week of September 8, 2007. ""Don't Blink" Is ... "Don't Blink" is a # 1 Billboard country, top 40 hot 100 single written by Casey Beathard and Chris Wallin, recorded by American ... On the Billboard Hot 100, "Don't Blink" debuted at number 79 on the chart dated September 22, 2007. The song is part of the ... The interviewer wants to know the older man's "secret to life", and the older man responds with "don't blink". Kevin John Coyne ...

*Ice blink

The ice blink was used by both the Inuit and explorers looking for the Northwest Passage to help them navigate safely. Water ... Ice blink is a white light seen near the horizon, especially on the underside of low clouds,1 resulting from reflection of ... sky "Ice blink". Athropolis. 2005. Retrieved Sep 3, 2010. This article incorporates text from a publication now in the public ...

*David Blink

Blink is also a composer. Under his direction, the YVCC Salsa Band has successfully released a CD of original music. Blink is ... In 2015, David Blink moved to Morelia, Mexico where he formed a new Big band at the Conservatorio de Las Rosas (Q5784215), ... David Blink is the Yakima Valley Community College director of instrumental music and jazz studies. He is a trumpet player and ... David Blink has been a featured artist at the Festival Internacional de Música de Morelia (Q5861015). He created large ensemble ...

*Blink (band)

... but a legal dispute with the Irish Blink resulted in their name change to Blink-182. Blink was formed in the early 1990s by ... "Blink Music Callcard (1043)". Callcards.ie. Retrieved 16 October 2017. Rankin, Nick. "Blink". The Irish Callcards Site. ... Despite Paradigm Records closing, Blink and Ministry programmer, Howie Beno, agreed to go ahead with plans for Blink's third ... The San Diego based pop punk band now known as Blink-182 was originally also called Blink, ...

*Blink dog

The blink dog was created for D&D, and has appeared in every edition of the game. Blink dogs are Good or Lawful, and therefore ... The blink dog appeared in set 3 of the Monster Cards series in 1982. For the second edition of AD&D, the blink dog was listed ... If an opponent seriously threatened the entire pack, the pack would flee by blinking out and not reappearing. The blink dog was ... Its combat strategy was further refined so that now the blink dog appeared beside an enemy, attacked, and then blinked away ...

*Krista Blunk

Blunk remains working for ESPN and Westwood One today. "Meet Pac-12 Network's Krista Blunk". "Former UE Great Krista Blunk ... Blunk left the stations to join the Golden State Warriors pre and post-game shows later that year. One year later Blunk would ... Blunk would later be inducted into the Tell City High School Hall of Fame. Krista Blunk played collegiate basketball with the ... After graduation Blunk decided to play professionally. Blunk would play overseas for N.S.W Australia from 1994-95 before ...

*Blink (airline)

"Blink buys MyJet and Blackbushe Airport", Corporate Jet Investor, [1] "Wijet's Blink buy creates largest VLJ air taxi company ... Blink Limited was founded by Peter Leiman and Cameron Ogden, who met at Harvard Business School. Ogden is the son of Sir Peter ... In May 2015 Blink announced the acquisition of MyJet, a Genoa based operator, with three Cessna Citation Mustang aircraft. This ... Blink is a British commercial aviation operation which provides private Jet travel using Cessna Citation Mustang very light ...

*Blink Home

Blink continues to operate independently as a independent subsidiary. It is anticipated that Blink's technology will be used ... Blink is a home automation company which produces battery-powered home security cameras and a video doorbell. The company was ... Subsequently, Blink later announced an outdoor security camera, home security system, and video doorbell. Amazon announced in ... Ricker, Thomas (2 January 2017). "Little Blink camera expands into whole-home security, for a price". The Verge. Vox Media. ...

*Susan Blinks

Susan M. "Sue" Blinks (born October 5, 1957) is an American dressage rider and trainer. She was best known for riding her ... Blinks spent her teens training with Marianne Ludwig. She worked as Equestrian Director at the University of Massachusetts and ... "Susan Blinks". Olympics at Sports-Reference.com. Sports Reference LLC. ...

*Blink comparator

The blinking technique can easily be performed on a computer screen rather than with a physical blink comparator apparatus as ... A blink comparator was a viewing apparatus used by astronomers to find differences between two photographs of the night sky. It ... The Projection Blink Comparator (PROBLICOM), invented by amateur astronomer Ben Mayer, was a low-cost version of the ... The blinking technique is less used today because image differencing algorithms detect moving objects more effectively than ...

*Blink (novel)

Blink is a 2003 novel by Christian author Ted Dekker. It was re-released in November 2007 under the title Blink of an Eye, ... Blink is set in the modern-day United States and in the Middle East, and features a Christian fiction perspective. Protagonist ...

*Blink Bonny

In September, Blink Bonny attempted to win her third classic when she was sent to Doncaster in for the St Leger. Blink Bonny's ... The incident came to be known as the "Blink Bonny riot". Blink Bonny's first run as a four-year-old in the Bentinck Memorial at ... Blink Bonny's defeat at Newmarket led to a loss in public confidence, and at Epsom on 1 June she started at odds of 20/1 in a ... In 1857 Blink Bonny won five of her seven races and became the second filly, after Eleanor, to defeat the colts in The Derby. ...

*Blink Indonesia

Blink or Blink Indonesia is a musical group from Jakarta, Indonesia. Blink formed in Jakarta on 23 July 2011. They later ... Blink - Cover Firework Blink - Cover What Makes You Beautiful Blink- "Sendiri Lagi" - First Television Performance https://www. ... BLINK (2013)[citation needed] Heart Beat (2015)[citation needed] SOPHIE & BLINK (2013) Putih Abu Abu Concert Putih Abu Abu ... m.liputan6.com/amp/2984155/girlband-blink-bubar-karena-masalah-ini "Blink, girl band yang juga punya kualitas suara". ...

*Blink Digital

... (previously known as Blink Solution) was launched in late 2009 by Dooj Ramchandani (now CEO) and Rikki Agarwal ( ... Blink Digital bagged a Gold for 'KFC [email protected]' in the 'Mobile Apps' category at the 2014 Campaign India Digital Crest Awards. ... Blink Digital's 'KFC [email protected]' won the 2014 Webby People's Voice award in the Augmented Reality category. This was the lone ... Blink Digital is a digital agency based out of Mumbai, India. It creates advertising and marketing products based in technology ...

*Attentional blink

Theory and instructions for attentional blink Computational Models of the Attentional Blink Attentional Blink App for win32. ... Not only that, but when the attentional blink would occur, whether it be at lag 1 or lag 2, and how deep of a blink it was, ... The attentional blink is related to, but distinct from the phenomenon of repetition blindness. Attentional Blink can be used in ... Attentional blinking occurs when the second target is in stage 1 which causes a delay. The attentional blink mirror a ...

*Rogier Blink

... (born 13 January 1982 in Groningen) is a Dutch rower. Blink took part in the World Championships of 2005 in Munich ... Athlete biography: Rogier Blink, beijing2008.cn, ret: Aug 14, 2008 http://www.olympic.org/olympic-results/london-2012/rowing/ ...
Another interesting way to formally test the hypodopaminergic state hypothesis of ADHD is by examining the frequency of spontaneous eye blinks. Early work in non-human primates demonstrated that dopamine-stimulating medications produce increases in blink rate whereas dopamine-inhibiting medications produce decreases in blink rate (see Groen et al., 2015). Further, patients with PD have two times lower blink rates than healthy individuals (Deuschl & Goddemeier, 1998). Sometimes they even suffer from medical eye problems because their eyes are no longer sufficiently protected from dehydration and filth.Spontaneous blink rate can thus be regarded as a reliable marker of the integrity of the dopamine system in the brain. We recently examined spontaneous eye blink rates in children with ADHD (Groen et al., 2015) and in contrast to the hypodopaminergic state hypothesis we found no reductions; neither did previous studies. Therefore, if it exists, the hypodopaminergic state in ADHD thus is much less ...
Eye blink rate, as well as eyelid twitches, have been used as an indicator of stress in humans but has not been examined in horses until now.
You can easily protect your eyes from eye strain, irritation and blink rate if youre not able to limit your digital device use.
In this paper, we present evidence for a temporal relationship between eye blinks and smile dynamics (smile onset and offset). Smiles and blinks occur with high frequency during social interaction, yet little is known about their temporal integration. To explore the temporal relationship between them, we used an Active Appearance Models algorithm to detect eye blinks in video sequences that contained manually FACS-coded spontaneous smiles (AU 12). We then computed the temporal distance between blinks and smile onsets and offsets. Our data shows that eye blinks are correlated with the end of the smile and occur close to the offset, but before the lip corners stop moving downwards. Furthermore, a marginally significant effect suggests that eye blinks are suppressed (less frequent) before smile onset. For computer-generated characters, this model of the timing of blinks relative to smiles may be useful in creating compelling facial animations ...
Previous researchers have reported that the ocular discomfort experienced by computer users may be associated with an increase in the percentage of incomplete blinks, rather than with an actual reduction in SEBR.17,18 Therefore, the advantage offered by the expanded display in terms of SEBR may not result in an actual reduction in ocular discomfort, particularly when considering the percentage of incomplete blinks observed with this reading condition. In effect, in contrast with hard-copy reading, reading in electronic format led to an increase in the percentage of incomplete blinks. In addition, this difference was particularly significant when comparing the expanded 330% display (13.5% of incomplete blinks) and the tablet (14.5% of incomplete blinks) with all hard-copy texts (from 0 to 5% of incomplete blinks), as well as with electronic reading at 100% (9% of incomplete blinks). These findings are in agreement with a recent investigation,17 although the difference in incomplete blinks between ...
List of 9 disease causes of Absent corneal reflex, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Absent corneal reflex.
The corneal reflex, also known as the blink reflex, is an involuntary blinking of the eyelids elicited by stimulation of the cornea (such as by touching or by a foreign body), though could result from any peripheral stimulus. Stimulation should elicit both a direct and consensual response (response of the opposite eye). The reflex occurs at a rapid rate of 0.1 seconds. The purpose of this reflex is to protect the eyes from foreign bodies and bright lights (the latter known as the optical reflex). The blink reflex also occurs when sounds greater than 40-60 dB are made. The reflex is mediated by: the nasociliary branch of the ophthalmic branch (V1) of the 5th cranial nerve (trigeminal nerve) sensing the stimulus on the cornea only (afferent fiber). the temporal and zygomatic branches of the 7th cranial nerve (Facial nerve) initiating the motor response (efferent fiber). the centre (nucleus) in the pons of brain stem. Use of contact lenses may diminish or abolish the testing of this reflex. The ...
Corneal reflex is a test done as a part of cranial nerves assessment. The test is done by touching the peripheral margin of cornea at the cornea scleral junction by a whisk of cotton. Its wise to avoid thick cloth to perform this test, since it can cause injury to the cornea. The cotton thread…
Piggy backing in my left is giving me tolerable vision at the moment but my eyes do get very dry, probably though the reduced oxygen levels as a result of two sets of lens, coupled with a poor tear production. Im told that you need to keep your blink rate up as high as possible to help overcome this but using a computer makes your blink rate lower as you tend to stare at the screen. So very regular breaks away from the screen are essential. And I can feel my lenses all the time too - they dont hurt but are quite uncomfortable and irritating at times. Im at Moorfields this week to get the right eye fitted with RGP/piggy back lens as well so itll be two dry eyes soon ...
In a previous study, we have shown that salt-sensitive normotensive subjects display an increased pressor and heart rate response to mental stress. In the present study, we extend these findings by demonstrating that these subjects also display an enhanced affective modulation of the startle-induced blink responses during presentation of standardized pictures selected from the IAPS.22 Thus, the present study is the first to demonstrate that central factors, which are involved in affective modulation, may play a role in the blood pressure response to changes in dietary salt intake and perhaps contribute to the development of hypertension in salt-sensitive normotensive individuals.. The modulation of startle-induced blink reactions during appetitive and aversive affective states is believed to reflect the modulating influence of the amygdaloid body on emotional reflex autonomic and somatomotor functions.27,28 Projections of the central nucleus of the amygdala to autonomic circulatory centers in ...
THE door slams shut and Im alone in a small, slightly foggy cubicle. The temperature is freezing but like nothing I have felt before. My breath quickens, my skin prickles and my eyes blink furiously. I feel uncomfortable and panicky. Will I last or should I make a quick escape?
... - Ask a question about Blink Contacts Lubricating Eye Drops, start a discussion about Blink Contacts Lubricating
... - Ask a question about Blink Contacts Lubricating Eye Drops, start a discussion about Blink Contacts Lubricating
Are you overpaying for Sulfoxaprim DS (Generic)? With Blink, the price you see is the price you pay, so always check the Blink price first. Save up to 80% by paying online and then choose free delivery or free pickup at your local pharmacy. Same pills. Way lower prices. Blink has an A+ rating from BBB.
Are you overpaying for Demarest Dricort (Generic)? With Blink, the price you see is the price you pay, so always check the Blink price first. Save up to 80% by paying online and then choose free delivery or free pickup at your local pharmacy. Same pills. Way lower prices. Blink has an A+ rating from BBB.
The roundish profiles that sometimes blink are brain cells in the cerebral cortex that have been stained with a special fluorescent dye that senses calcium inside the cell. As brain cells fire electrical signals to communicate with each other, the calcium increases inside them, so the fluorescent dye allows us to see the activity of brain cells ...
View Blink presentations online, safely and virus-free! Many are downloadable. Learn new and interesting things. Get ideas for your own presentations. Share yours for free!
Stockholm Syndrome by Blink 182 Tab Different Versions Chords, Tab, Tabs. Key Variations. Play Advices. Chords Diagrams. Guitar Tabs Universe
Blink-182 F/ - Blink 182 -05- What`s My Age Again Lyrics. I took her out, it was a Friday night I wore cologne to get the feeling right We started makin out and she took off my pants But then I tur
A simple automatic function. Like balancing hormones in the blood, or regulating body temperature, or a heartbeat. They say a person blinks an...
Evinger, C.; Basso, M. A.; Manning, K. A.; Sibony, P. A.; Pellegrini, J. J. und Horn, Anja K. E. (1993): A role for the basal ganglia in nicotinic modulation of the blink reflex. In: Experimental Brain Research, Vol. 92: S. 507-515 [PDF, 2MB] ...
Fresh comfort with every blink.TITLE: Aquify Long-Lasting Comfort Drops Fresh comfort with every blink. Special blink activated ingredient sodium...
Page 2 - Since 1998, my mother has been plagued with numerous health problems, but we had been able to manage. My father has been partially paralayzed from a CVA since 1990. Last Thursday night, I got in from
Suddenly Morris Goodman went from happy and healthy to a man whose life hung in the balance. See how he escaped death and earned the name The Miracle Man.
InfoBank, KnowledgeBanks field data catalog, is a structured information storage scheme of databases and software that provide organized access to USGS Coastal and Marine data and metadata.
Sean has always been very fit and healthy, and in the blink of an eye that al… Maria Alejandra Giraldo needs your support for PLEASE HELP US HELP SEAN RECOVER
The statistics are horrifying. The danger is real - and it can wreak life-changing devastation anytime, anywhere, in the blink of an eye. The destruction ripples out, impacting two out of three people in their life time. ...
My beautiful baby Tessa turned 10 weeks old on Tuesday! I really, truly, have no idea how time has passed so quickly. How did time creep by so slowly when she was in my tummy and I was anxiously awaiting her... and now 10 weeks have passed in the blink of an eye? You need…
Benign Essential Blepharospasm is a disorder associated with atypical spasms or blinking of the eyelids. The condition arises as a result of the inability to control the muscle contractions around the eyelids, leading to involuntary blinking of eyelids in an abnormal manner. Know the causes, symptoms, treatment, pathophysiology of benign essential blepharospasm.
Abstract: Funds are available for support of research directly related to blepharospasm or Meiges Syndrome, both forms of cranial dystonia. Research proposals must relate specifically to benign essential blepharospasm and Meige to include new treatments, pathophysiology and genetics, photophobia, and dry eye ...
In well-trained animals, infusion of the GABA-B agonist baclofen into the cerebellar interpositus nucleus and overlying cortex abolished the conditioned response (CR) with no effect on the unconditioned response (UR) with doses at or above 5.0 mM. Infusion of the GABA-B antagonist CGP 5584-5A alone had no effect on the CR or UR. However, administration of 5 mM baclofen soon after infusion of CGP 5584-5A (15 min) resulted in no reduction of percent CR and only partial reduction of CR amplitude. Naive animals given interpositus infusions of baclofen during training showed no learning, yet learned normally in postinfusion training. The distribution of (radiolabelled) baclofen was localized and remained within the cerebellum. The results presented here are consistent with a growing body of literature supporting the hypothesis that the memory trace for eyeblink conditioning is formed and stored in the cerebellum and may involve GABAergic mechanisms.
A pair of studies examined how cortical intracerebellar stimulation (ICS) affects eyeblink conditioning in the rabbit. Rabbits were implanted with chronic bipolar stimulating electrodes in the cell body layers of cerebellar lobule H-VI. Brief (40 ms) trains of intracranial stimulation (100 Hz, 250 microA) were delivered during training trials [forward pairings of a tone-conditioned stimulus (CS) with an air puff unconditioned stimulus (US)]. In Experiment 1, the onset of ICS varied randomly within sessions. US-onset-coincident ICS proved detrimental to the maintenance of conditioning [measured as the percentage of trials on which conditioned responses (CRs) were made] compared to ICS that ended 60 ms before US onset. Based on these findings, a second experiment compared a group trained with ICS consistently delivered at US onset to groups trained with ICS consistently delivered either at CS onset or between the two stimuli, as well as to unstimulated control subjects. Animals receiving CS- or US
The first record of blepharospasm and lower facial spasm was found in the 16th century in a painting titled De Gaper. At that time, and for several ensuing centuries, patients with such spasms were regarded as being mentally unstable and often were institutionalized in insane asylums.
The first record of blepharospasm and lower facial spasm was found in the 16th century in a painting titled De Gaper. At that time, and for several ensuing centuries, patients with such spasms were regarded as being mentally unstable and often were institutionalized in insane asylums.
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There is a lot of evidence for the impact of acute glucocorticoid treatment on hippocampus-dependent explicit learning and memory (memory for facts and events). But there have been few studies, investigating the effect of glucocorticoids on implicit learning and memory. rnWe conducted three studies with different methodology to investigate the effect of glucocorticoids on different forms of implicit learning. rnIn Study 1, we investigated the effect of cortisol depletion on short-term habituation in 49 healthy subjects. 25 participants received oral metyrapone (1500 mg) to suppress endogenous cortisol production, while 24 controls received oral placebo. Eye blink electromyogram (EMG) responses to 105 dB acoustic startle stimuli were assessed. Effective endogenous cortisol suppression had no effect on short-term habituation of the startle reflex, but startle eye blink responses were significantly increased in the metyrapone group. The latter findings are in line with previous human studies, which ...
There is a lot of evidence for the impact of acute glucocorticoid treatment on hippocampus-dependent explicit learning and memory (memory for facts and events). But there have been few studies, investigating the effect of glucocorticoids on implicit learning and memory. rnWe conducted three studies with different methodology to investigate the effect of glucocorticoids on different forms of implicit learning. rnIn Study 1, we investigated the effect of cortisol depletion on short-term habituation in 49 healthy subjects. 25 participants received oral metyrapone (1500 mg) to suppress endogenous cortisol production, while 24 controls received oral placebo. Eye blink electromyogram (EMG) responses to 105 dB acoustic startle stimuli were assessed. Effective endogenous cortisol suppression had no effect on short-term habituation of the startle reflex, but startle eye blink responses were significantly increased in the metyrapone group. The latter findings are in line with previous human studies, which ...
List of 24 causes for Babinskis reflex and Diminished corneal reflex in one eye and Incomprehensible speech, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Top 10 Destinations for Medical Tourism Medical tourism can be considered a kind of import: instead of the and utricle, which enables the body to maintain its balance, posture, and orientation. In the past few years the salary has shot up a medical assistant is not a difficult task. It damages or kills the immune…
Eyeblink is a complex solution to dry eye syndrome. Eyeblink measures your blink rate using webcam. Eyeblink trains you to blink more using interactive reminder, which rolls out of the upper right corner of the screen and go away after you blink. Eyestrain, dryness, itchiness, burning, red eyes or blurred vision are common symptoms of dry eye syndrome. Healthy human blinks 10 to 15 times per minute. In front of the computer screen 70% of users, blink up to 60% less. One of the main reason ...
Essential blepharospasm is a debilitating disorder of progressive involuntary spasms of the eyelid muscles. Other muscles in the face or neck may be involved as well. Terms that sometimes are used in the description of this problem include dystonia (impaired or disordered muscle tone) and dyskinesia (a defect in voluntary movement). The onset of blepharospasm is typically in the fifth to sixth decade and is more common in women than in men. Although the cause of essential blepharospasm is incompletely understood, it is thought to be a result of "miscommunication" in the area(s) of the brain responsible for control of the involved muscles.. The onset of essential blepharospasm usually is heralded by an increase in blinking or squinting with progression toward repetitive forceful closure and difficulty opening the eyelids. Blepharospasm is often made worse by stress, fatigue, bright lights, watching television or driving, and social interactions. Functional blindness in the presence of an ...
Trace eyeblink conditioning is useful for studying the interaction of multiple brain areas in learning and memory. The goal of the current work was to determine whether trace eyeblink conditioning could be established in a mouse model in the absence of elicited startle responses and the brain circuitry that supports this learning. We show here that mice can acquire trace conditioned responses (tCRs) devoid of startle while head-restrained and permitted to freely run on a wheel. Most mice (75%) could learn with a trace interval of 250 ms. Because tCRs were not contaminated with startle-associated components, we were able to document the development and timing of tCRs in mice, as well as their long-term retention (at 7 and 14 days) and flexible expression (extinction and reacquisition). To identify the circuitry involved we made restricted lesions of the medial prefrontal cortex (mPFC) and found that learning was prevented. Furthermore, inactivation of the cerebellum with muscimol completely ...
Information about Benign Essential Blepharospasm from the National Institute of Neurological Disorders and Stroke (NINDS). Includes description, treatment, prognosis and research. ...
My research focuses upon delineating processes of developmental change, creating explanatory models of how biological, behavioral, and social-cultural factors act together in development, and detailing how developing organisms own modes of functioning shape their subsequent paths of development. I address these issues mainly through the study of how human newborns become transformed into three-year-olds who have mastered several of the basic forms of cooperative action valued within their culture (e.g., social games, verbal conversations, cooperative problem-solving). Four interrelated lines of inquiry are ongoing. The first relates differences among very-prematurely-born infants in early central nervous system development to their paths of social-communicative development over the first two years of life. The second uses classical eyeblink conditioning paradigms to better characterize the behavioral differences between preterm and full-term infants in terms of cognitive, attentional, and ...
I recently had the pleasure of speaking with Nilda Rendino, Vice President and Advocacy Chair of the Benign Essential Blepharospasm Research Foundation and Dona Norton on the topic of blepharospasm, a devastating disease which has affected both of them and often times goes years without being properly diagnosed. If you suffer from dry eyes, excessive blinking and sensitivity to light, you may (according to Merz Pharmaceuticals) be one of the 53% who goes at least a year without a proper ... View the Post ...
The researchers found that patients showed a significantly reduced number of conditioned eyeblink responses before alcohol administration versus controls.
We have studied a simple form of motor learning in the human brain so as to isolate activity related to motor learning and the prediction of sensory events. Whole-brain, event-related functional magnetic resonance imaging (fMRI) was used to record activity during classical discriminative delay eyeblink conditioning. Auditory conditioned stimulus (CS+) trials were presented either with a corneal airpuff unconditioned stimulus (US, paired), or without a US (unpaired). Auditory CS- trials were never reinforced with a US. Trials were presented pseudorandomly, 66 times each. The subjects gradually produced conditioned responses to CS+ trials, while increasingly differentiating between CS+ and CS- trials. The increasing difference between hemodynamic responses for unpaired CS+ and for CS- trials evolved slowly during conditioning in the ipsilateral cerebellar cortex (Crus I/Lobule HVI), contralateral motor cortex and hippocampus. To localize changes that were related to sensory prediction, we compared trials
Classical conditioning of motor responses, such as the eyeblink response, is an experimental model of associative learning and of adaptive timing of movements. A conditioned blink will have its...
3) Schedule study sessions starting early in the morning rather than late night. The common concept is, "At night I concentrate better". For an exam it is not how much you read but what you can remember on call. Studying in daytime is better as you will study faster with a far better reproducible memory than the same amount at night when fatigue causes loss of ability to concentrate.. 4) Adjust the lighting in your study area. Though you want the area in your study to be well lit, make sure the room has enough ambient lighting. Studying in a dark room leads to eye strain as the contrast between the lighted and unlighted areas is too much. Light coming from a lamp at your side and back is easier on the eyes.. 5) When we concentrate hard, the blink rate of the eyes drops significantly. This leads to dryness, blurring and diffused vision. Blink frequently whenever you study for long periods at a time. Blinking helps to keep eyes moist. Dry eyes leads to tired eyes. Using tear lubricants is also a ...
In this study, we characterized the pharmacological effects of dexmedetomidine on the basis of increasing steady-state plasma concentrations using defined stimulus-response and continuous effect measurements in rats. Table 2 demonstrates that dexmedetomidine, when administered alone, can be typified as a drug that creates bradycardia, sedation/hypnosis (absence of whisker and righting reflexes), sympathoadrenal blocking effects, and a blood pressure-increasing effect at plasma concentrations below 2.5 ng/ml. Higher plasma concentrations are needed to loose the startle reflex, tail-flick, tail clamp, and corneal reflex responses. The EC50value for loss of corneal reflex could not be determined accurately because the measure was lost in only a few rats. This indicates that even higher plasma concentrations of dexmedetomidine should have been targeted to abolish this measure. At the estimated EC50 for loss of response to tail clamp, only mild ventilatory depressant effects were observed, which is ...
Even if all external circumstances are kept equal, the oculomotor system shows intra-individual variability over time, affecting measures such as microsaccade rate, blink rate, pupil size, and gaze position. Recently, some of these measures have been associated with ADHD on a between-subject level. However, it remains unclear to what extent these measures constitute stable individual traits. In the current study, we investigate the intra-individual reliability of these oculomotor features. Combining results over three experiments (,100 healthy participants), we found evidence for intra-individual reliability over different time points (repeatability) as well as over different conditions (generalization). Furthermore, we correlated oculomotor variability with self-assessed ADHD tendencies, mind wandering, and impulsivity, and found evidence against such correlations. As such, the oculomotor system shows reliable intra-individual reliability, but its use for distinguishing self-assessed individual ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
The corneal reflex test (blink test) examines the reflex pathway involving cranial nerves V and VII. Classically the provider lightly touches a wisp of cotton on the patients cornea. This foreign body sensation should cause the patient to reflexively blink.. This maneuver always makes me a little worried about causing a corneal abrasion, especially if you are examining a very somnolent patient. You are wondering - Is there no blinking because youre not touching the cornea hard enough? You apply harder pressure but still no blink. You repeat the test and now the patient finally blinks. Thats 3 times youve just scraped against the cornea.. Whats an alternative approach?. ...
Humans blink 20 times every minute. But even 3 times is enough to moisten our eyes. So why do we blink so frequently? The answer is still a huge mystery. At this lecture, Ill talk about things such as when humans blink, what is happening in the brain when we blink, and what effects this blinking can have on others. Ill also introduce a variety of interesting topics in an easy-to-understand format, from research using magic and humanoid robots, to research that measures and controls cranial nerve activity.. Attendance Fee: 1,620 yen. ...
A manager that allows fields to be placed in two eyelids that slide onto the screen on demand. This eye blink displays fields along the top and bottom of the screen for a short period of time (the default is 1.2 seconds) before they are pulled out in an un-blinking animation. Any user input (trackball/keyboard/touch-screen/tilt) will cause the eyelids to close for a short time period as defined by ...
A manager that allows fields to be placed in two eyelids that slide onto the screen on demand. This eye blink displays fields along the top and bottom of the screen for a short period of time (the default is 1.2 seconds) before they are pulled out in an un-blinking animation. Any user input (trackball/keyboard/touch-screen/tilt) will cause the eyelids to close for a short time period as defined by ...
Medium to large Cichlids have, in general, a reputation of aggression towards tankmates, intolerance to others of their kind, and just a bad attitude in the aquarium. To dispel those myths, in this post well study what I call the mellow fellows; that is, the medium to large Cichlids that, to a lesser or greater extent, are completely passive in the aquarium. Some, of course, are more passive than others, and one or two can suddenly turn from Dr. Jeckle to Mr. Hyde in an eye blink, or will
That hasnt happened yet. But the clear focus of sexual-orientation research has shifted to biological causes, and there hasnt been much science produced to support the old theories tying homosexuality to upbringing. Freud may have been seeing the effect rather than the cause, since a father faced with a very feminine son might well become more distant or hostile, leading the boys mother to become more protective. In recent years, researchers who suspect that homosexuality is inborn - whether because of genetics or events happening in the womb - have looked everywhere for clues: Prenatal hormones. Birth order. Finger length. Fingerprints. Stress. Sweat. Eye blinks. Spatial relations. Hearing. Handedness. Even "gay" sheep ...
Blepharospasm Australia is not connected to any medical facility or medical practitioner. All contributors to the site are volunteers with expertise in various fields of endeavour excluding the medical profession.. Website content is provided only to inform patients and general enquirers about Benign Essential Blepharospam (BEB) and should in no way replace information from medical practitioners.. Lyn Smith is Website Editor responsible for the website and its content with the exception of Case Histories which are supplied by members and published anonymously.. Users of the website must at all times behave with respect and honesty.. Users filling in registration forms should make sure that the information they choose to share should be accurate to the best of their ability. Please read our Privacy Policy before submitting forms.. Users can choose whether to allow contact via email by people in their own state enquiring about BEB.. Our website does not host any form of advertising.. This website ...
In a previous UI Design Blink, I pointed to the design practice of arranging figures and explanatory text closely together, and justified it with the contiguity effect described by the cognitive load theory. However, the same theorys redundancy effect implies that this practice can be detrimental for users for whom a figure is self-explanatory (I will call them expert users in the following). Therefore, I asked the obvious questions: How can designers know in advance if their users are experts, casual users, ore mere beginners? And if designers do not know their audience, how can they address this dilemma? In this UI Design Blink, I primarily focus on the second question and revive an - admittedly, old - design proposal. Please note that the topic of designing for different user groups in general is a huge field in itself, which would definitely exceed the scope of this article. When designers know their audience, they can act appropriately. For example, they can place descriptive text ...
The Film titled Time To Change: REACTIONS was done by Blink Productions, Dare, The Mill advertising agencies for Time To Change in United Kingdom. It was released in Jun 2011.
On 06 Dec 2004 at 00h12, Cedric Pradalier wrote: Hi Cedric, , + return sprintf(buf, %c\n, pmu_blink_led_activated?1:0); why not simply sprintf(buf, %d\n, pmu_blink_led_activated) ? , + pmu_blink_led_activated = newact?1:0; pmu_blink_led_activated = (newact != 0); is enough and more nice imho. , + device_create_file (&of_hd_dev-,dev, &dev_attr_blinking_led); where is dev_attr_blinking_led defined ? -- Colin http://ayttm.sf.net/ : Chat with your friends via msn, aim, yahoo, and more ...
They then hooked up their chip to a rat whose cerebellum had been disabled (they did this externally, with the chip connected to the brain by electrodes--they did not implant the chip in the rats brain). Before hooking up their synthetic chip, they tried to teach the rat a behavior with its cerebellum switched off by combining an auditory tone with a puff of air to the rats eye that caused it to blink. The rat shouldve quickly learned to blink its eye at the stimulus of the tone alone without the puff of air (think Pavlov), but with its cerebellum disabled it could not ...
is 6 and I noticed for no reason at all her eyes would roll up in her head (towards her right) for just a second and then she blinks a couple of times and shes fine. Then she will blink off and on a ...
In a fraction of a second, imagine seeing a dozen pictures flash by. You might think it would be impossible to identify any images you see for such a short time.
The problem of losing the ability to blink after damage to the nerve that controls the process - a pair of glasses that sends a command to force a blink.
A novel disease in songbirds has rapidly evolved to become more harmful to its host on at least two separate occasions in just two decades, according to a new study. The research provides a real-life model to help understand how diseases that threaten humans can be expected to change in virulence as they emerge.
Humans blink about 16 times a minute - 15,360 times a day. For people with trachoma, every blink is very painful. Read more about this terrible disease.
bruce56j, 1997 Dodge Ram 1500, 5.9, My left side turn signal lights dont blink but the right side works fine. I replaced the bulbs with new ones and it st...
Latin: to close the eyes, to blink, to wink at [a crime], to overlook [errors], connive at; to be privy to [secretly knowing about]; to be tightly closed
You blink your eyes a few times, a decade slips by, and all of a sudden youre looking back at a whole different era.For a refresher, 2002 was the year that sales of Hummers exploded, that the averag
Soos ons soek en antwoorde vind, deel ons dit graag met ander wat dalk ook na blink planne soek. Sommige planne sal ons eie wees en ander is dalk oulike idees wat ons langs die pad raakgeloop het of van vriende en vriendinne ontvang het. Wanneer ons n lekker resep of n wenk kry of raad vir die tuin, deel ons dit ook graag met julle. ...
Find the Blink Price & Information for Levaquin - as low as $10.95 - pick up at your pharmacy CVS, Walmart & more. Price transparency and up to 80%
purpose. To demonstrate the feasibility of indirectly measuring the precorneal tear film thickness and pre- and postlens tear film (PLTF) thickness using optical coherence tomography (OCT).. methods. Central corneal thickness (C1) which includes the tear film (T) of both eyes of 40 non-contact lens wearers was measured using OCT after calibration. The mean age of the 40 subjects was 31.2 ± 9.3 years with a mean horizontal K-reading of 7.87 mm. Rigid contact lenses with base curves 0.3- to 0.5-mm steeper than the flattest K of the eye were fitted to measure real corneal thickness (C2), independently of the postlens tear film. T was calculated by T = C1 − C2. To measure pre- and postlens tear film thickness, Focus Night & Day and Acuvue lenses (Vistakon, Johnson & Johnson Vision Care, Jacksonville, FL) were fitted on both eyes. Central soft lens thickness (L1), which includes the prelens tear film (P), was measured by OCT in situ and in saline in a wet cell (L2). P was calculated by P = L1 − ...
The orbicularis oculi is a muscle in the face that closes the eyelids. It arises from the nasal part of the frontal bone, from the frontal process of the maxilla in front of the lacrimal groove, and from the anterior surface and borders of a short fibrous band, the medial palpebral ligament ...
[Changes in the blink reflex in patients with essential blepharospasm and hemifacial spasm].: Electrophysiological investigations have been carried out in 46 pa
JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research. Watch our scientific video articles.
Evidence-based recommendations on transcutaneous electrical stimulation of the supraorbital nerve for treating and preventing migraine
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.. MedCram: Medical education topics explained clearly including: Respiratory lectures such as Asthma and COPD. Renal lectures on Acute Renal Failure and Adrenal Gland. Internal medicine videos on Oxygen Hemoglobin Dissociation Curve and Medical Acid Base. A growing library on critical care topics such as Shock, Diabetic Ketoacidosis (DKA), and Mechanical Ventilation. Cardiology videos on Hypertension and heart failure. VQ Mismatch and Hyponatremia lectures have been popular among medical students. The Pulmonary Function Tests (PFTs) videos and Ventilator associated pneumonia bundles and lectures have been particularly popular with RTs. NPs and PAs have given great feedback on Pneumonia Treatment and Liver Function Tests among many others. Many nursing students have found the Asthma and shock lectures very helpful. BoardVitals helps physicians, nurses, medical students, and other healthcare professionals ...
Definition of classical conditioning in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is classical conditioning? Meaning of classical conditioning as a legal term. What does classical conditioning mean in law?
In one recent study Delgado tested the device on a monkey that had electrodes, vestiges of his previous work - implanted in two separate regions of its motor cortex. Before the trail began, he demonstrated how activating the first electrode caused the animal to clench its fist. Activating the second electrode triggered an eye blink. Then the animals head was capped with a hood containing a transmitter aimed at the cerebellum, a structure in the lower hind part of the brain. Several hours later, the special hood was removed, and the electrodes were activated again. There was a marked difference in the animals evoked response. What was once a mere blink of the eye had become a wince involving the eyebrow and cheek muscles. And the clenched fist had been transformed into a jerk of the entire lower arm.. For better or worse, electromagnetic fields have emerged as a potent force - a discovery with staggering implications for the future of medicine, science, industry, and the military.. Louis ...
John Disterhoft is the author of this article in the Journal of Visualized Experiments: Whisker-signaled Eyeblink Classical Conditioning in Head-fixed Mice
My son who is 7, developed an eye tick about 6 mos ago. It did go away for about 2 wks but is back and in full swing. His eyes blink rapidly. We notice it is particularly bad if he is nervous about ...
More than half of patients coping with a form of nearly complete paralysis called locked-in syndrome indicated -- through eye blinks in some cases -- that they were getting some satisfaction in life, though 8 percent had often thought of suicide.
What is Orbicularis Oculi, function, definition, location, pictures and significance. Damage to the area can cause complications which we need to know about.
Blink Tears Lubricating Eye Drops at Walgreens. Get free shipping at $35 and view promotions and reviews for Blink Tears Lubricating Eye Drops
... - 35% off Authentic Blink glasses frames, 50% off Lenses, Free Shipping. Highest Quality Lenses, A+ BBB rating since 1999, Satisfaction Guaranteed.
This year I was introduced to an incredible company that is really shaking up the way we think about our lashes - Blink! The Eyelash Expert. Blink! not only creates eyelashes that will make your heart flutter and your face smile like crazy but they actually care about the condition of your lashes. Janice Mastin…
BLink 3.0 :: DESCRIPTION BLink (Bayesian Linkage) is a software to compute linkage disequilibrium based on a bayesian estimate of D ::DEVELOPER Bios, University of GranadaGranada , Spain :: SCREENSHOTS
Definition of Unconditioned stimulus with photos and pictures, translations, sample usage, and additional links for more information.
A method and apparatus for thin film thickness measurements with thermal waves in which heating and detection laser beams are focused onto the film, normal to the surface of the film, with the two beams parallel and non-coaxial.
My mom's eyes constant tear; she constantly blinks which has impacted her doing normal everyday activities; her vision - Answered by a verified Eye Doctor
According to Colin Leroy, on Sun, 5 Dec 2004 14:42:33 +0100, ,On 06 Dec 2004 at 00h12, Cedric Pradalier wrote: , ,Hi Cedric, , ,, + return sprintf(buf, %c\n, pmu_blink_led_activated?1:0); , ,why not simply sprintf(buf, %d\n, pmu_blink_led_activated) ? I like to ensure that whatever the implementation of this boolean, the textual output stays the same. , ,, + pmu_blink_led_activated = newact?1:0; , ,pmu_blink_led_activated = (newact != 0); ,is enough and more nice imho. I wanted to have either 1 or 0 in this boolean, not whatever int sent in the buffer. , ,, + device_create_file (&of_hd_dev-,dev, &dev_attr_blinking_led); , ,where is dev_attr_blinking_led defined ? , +static DEVICE_ATTR (blinking_led, S_IRUGO , S_IWUSR, + show_blinkingled_activity, set_blinkingled_activity); Note that the patch is made from a compiled and tested pmac.c ;o) -- Cedric Pradalier Research Engineer CSIRO - ICT Centre ...
Manipulative Physiol Ther Online Milwaukee Manforce-50 The blink reflex and the Canada , Cheap Aurogra Tablets Frankfort, Cheap Vigora Tablets Cheyenne, Online Tazzle 10mg Washington
I remember once upon a time eating at a restaurant where each table had a little light with a button on it. Push the button and the light will go on, indicating to the waitstaff that you would like some service. Dont push the button and the waitstaff will leave you alone. With modern technology, this could be improved slightly by having the button also trigger an annunciator in the kitchen or (in larger restaurants) in another room. Additionally, the light could be made to blink at a rate indicating how long it has been on (e.g. push the button and light goes on. After 60 seconds it starts to blink slowly. After 2 minutes it blinks faster. Another minute and it starts blinking rapidly. This would allow the waitstaff to somewhat prioritize service to the customer who has been waiting longest. Anyone else like this idea? I wonder why I havent seen it elsewhere? BTW, I think the restaurant was York Steak House in the Janesville Mall (Janesville, WI); I would have been there circa 1986 or so ...
It is not normal. Usually the blinking movement will not cause the noise from the eyes. Your eyeballs or other parts may get infection and are affected by the blinking movement. Youd better go to have a check on the eyes to see whether there are the problems at the eyes. If you have, you should treat them as soon as possible.
Life has finally calmed down enough to go back and visit our 2 frozen embryos and try to bring one of them home for good. We started this conversation way back in April, when we quickly discovered that my insurance through Galesburg didnt cover anything infertility related. Fortunately I had already accepted a new position for the fall in Knoxville and infertility would be covered. It was a long wait all summer, but we knew it was the logical choice. We made the 1st appt possible with Dr. Figges office, however it was no longer dr Figges office. Dr. K is the new dr there and we met with her the first week of Sept. Everything looked good to go to do a FET with my next cd1, which happened to be the following week. We called on cd1 and got the most unexpected news, that cycle period was full, we would have to wait. Unfortunately waiting would put our due date smack dab in the middle of Chucks busy season, summer. And then comes the start of the school year, also not a great time to try and have ...
Four years ago Jack Maloney, Brownsburg, and his son, Peter, and other helpers were working on their grain leg. Their mission was to switch from handling corn to binning soybeans.
If you frequently use a computer, keep in mind this can harm your eyes. If they start to dry out, blink frequently. You should also cut back on screen glare. If you can, try getting an anti-glare screen. Lastly, it is important that your eyes are positioned so the top part of the screen is level. You want to be looking down when you view your screen ...
Looking for online definition of orbital part of orbicularis oculi muscle in the Medical Dictionary? orbital part of orbicularis oculi muscle explanation free. What is orbital part of orbicularis oculi muscle? Meaning of orbital part of orbicularis oculi muscle medical term. What does orbital part of orbicularis oculi muscle mean?
PURPOSE. To demonstrate the feasibility of indirectly measuring the precorneal tear film thickness and pre- and postlens tear film (PLTF) thickness using optical coherence tomography (OCT). METHODS. Central corneal thickness (C1) which includes the tear film (T) of both eyes of 40 non-contact lens wearers was measured using OCT after calibration. The mean age of the 40 subjects was 31.2 ± 9.3 years with a mean horizontal K-reading of 7.87 mm. Rigid contact lenses with base curves 0.3- to 0.5-mm steeper than the flattest K of the eye were fitted to measure real corneal thickness (C2), independently of the postlens tear film. T was calculated by T = C1 - C2. To measure pre- and postlens tear film thickness, Focus Night & Day and Acuvue lenses (Vistakon, Johnson & Johnson Vision Care, Jacksonville, FL) were fitted on both eyes. Central soft lens thickness (L1), which includes the prelens tear film (P), was measured by OCT in situ and in saline in a wet cell (L2). P was calculated by P = L1 - L2. ...
Looking for online definition of pars palpebralis musculi orbicularis oculi in the Medical Dictionary? pars palpebralis musculi orbicularis oculi explanation free. What is pars palpebralis musculi orbicularis oculi? Meaning of pars palpebralis musculi orbicularis oculi medical term. What does pars palpebralis musculi orbicularis oculi mean?
The bottom line?. The authors concluded: "This study suggests a potentially meaningful role for zinc and/or phytase supplementation in increasing the degree and duration of botulinum toxin effect in the treatment of cosmetic facial rhytids, benign essential blepharospasm, and hemifacial spasm.". When a skeletal muscle nerve ending is stimulated it releases acetylcholine, which triggers an impulse to the muscle. Botulinum toxin blocks release of acetylcholine at the neuromuscular junction. As shown in the photo above, zinc is part of the botulinum toxin structure. A more detailed explanation is here.. Phytases are enzymes that increase zinc absorption from the intestines, making more available in the circulation and at the botulinum toxin site of action.. This study is important because it shows that taking more zinc may increase the response and duration of effect of "Botox" type drugs. This may be particularly useful for patients who experience a decline in response over time.. 4/10/13 9:28 ...
This page provides relevant content and local businesses that can help with your search for information on Blepharospasm Treatment. You will find informative articles about Blepharospasm Treatment, including Botox As Treatment For Blepharospasm. Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Mitchell, SD that can help answer your questions about Blepharospasm Treatment.
Many studies have documented the relationship between adverse early experience and the development of psychiatric disorders. Understanding the mental health consequences of perinatal stressors is crucial to preventative treatment. Neonatal maternal separation in the rat is a good model system for assessing the effects of adverse early experience, and eyeblink conditioning is a good model for studying the relationship between neonatal stress and adult learning and memory. Previously, I showed that daily neonatal maternal separation (1h/day on postnatal days 2-14) increases plasma corticosterone levels during the first and second postnatal week. Further, I showed that neonatal maternal separation impairs adult eyeblink conditioning and produces a correlated increase in glucocorticoid receptor expression in the posterior interpositus nucleus of the cerebellum. My dissertation research is focused on characterizing the role of glucocorticoids in this effect. I measured cerebellar glucocorticoid ...
One of the major complications of a peripheral facial nerve palsy (PFP) is the occurrence of corneal ulceration due to lagophthalmos-that is, incomplete closure of the affected eyelid. It is widely accepted that lagophthalmos after PFP is directly caused by paresis of the orbicularis oculi muscle (eyelid closure muscle). Yet, some of the signs and symptoms, which may be observed in patients with PFP cannot be explained by paresis of the orbicularis oculi muscle alone. First of all, gentle closure of the eyelid, as for example occurs when a person falls into sleep, is completely brought about by inhibition of the tonic activity of the levator palpebrae muscle (eyelid opener muscle).1 Secondly, upward and downward saccadic lid movements, accompanying saccadic eye movements, are mainly due to modification of the tonic activity of the levator palpebrae muscle. Finally, the downward and upward smooth pursuit movements of the lids are again secondary to alterations in the level of activity of the ...

Blinking - WikipediaBlinking - Wikipedia

Types of blink[edit]. There are three types of blink. Spontaneous blink[edit]. Spontaneous blinking which is done without ... Blinking in everyday life[edit]. Children[edit]. Infants do not blink at the same rate of adults; in fact, infants only blink ... Voluntary blink[edit]. Voluntary blink is larger amplitude than Reflex blink, with the use of all 3 divisions of the ... A reflex blink is not necessarily a conscious blink either; however it does happen faster than a spontaneous blink.[1] Reflex ...
more infohttps://en.wikipedia.org/wiki/Blinking

Blinking lights! | MetaFilterBlinking lights! | MetaFilter

Blinking lights!. March 28, 2008 2:45 AM Subscribe. This is a cool game you can download. Here are some rule books for it.. Ok ... I am afraid to open the application, knowing that it may take days of my life to reemerge, blinking and shambling, into the ...
more infohttps://www.metafilter.com/70302/Blinking-lights

blinking battery lightblinking battery light

the yellow lights blink really fast then the green blinks slow. any solutions? ... blinking battery light. i have a dell inspiron 1150 and i recently had to replace the power supply. i ordered it from ... except now the battery light on my laptop blinks green once then yellow three times and then repeats over. ... https://www.experts-exchange.com/questions/21923945/blinking-battery-light.html copy ...
more infohttps://www.experts-exchange.com/questions/21923945/blinking-battery-light.html

Blinking - Health Video: MedlinePlus Medical EncyclopediaBlinking - Health Video: MedlinePlus Medical Encyclopedia

During the normal course of a day, a person blinks an average of 15 times a minute to keep the eyes ... The nervous system enables a person to blink to prevent harmful substances from getting in the eyes. ... During the normal course of a day, a person blinks an average of 15 times a minute to keep the eyes healthy. The lacrimal gland ... Blinking also provides the eyes with protection from foreign objects.. When the eye becomes irritated, the lacrimal gland ...
more infohttp://medlineplus.gov/ency/anatomyvideos/000010.htm

Blinking, crying and seeing starsBlinking, crying and seeing stars

But why do they do all these things? Why do we blink? Why do we cry? What are the different types of tears? And how can you ... Our eyes blink, shed tears, see stars, and can even offer clues to underlying illnesses. ... We blink, cry and see stars - but what makes our eyes to react like that? Why do we blink? What role does our retina play? ... Did you know...? The amount we blink differs from one person to the next. A newborn baby only blinks about twice a minute, ...
more infohttps://www.zeiss.com/vision-care/int/better-vision/understanding-vision/blinking-crying-and-seeing-stars.html

AFGHANISTAN BLINKING RED. - The American ProspectAFGHANISTAN BLINKING RED. - The American Prospect

AFGHANISTAN BLINKING RED. In case you arent worried enough about Iraq, you should start worrying about Afghanistan, because ...
more infohttps://prospect.org/article/afghanistan-blinking-red./

blink-182 on Apple Musicblink-182 on Apple Music

California trio blink-182 is the most popular band to emerge from the post-Green Day mainstream explosion of pop-punk. At a ... time when competition with teen pop and nu-metal were not unheard of, blink-182 released a steady stream of hits, bolstered by ... About blink-182. California trio blink-182 is the most popular band to emerge from the post-Green Day mainstream explosion of ... The third blink-182 LP, Dude Ranch, was jointly released in 1997 by Cargo and MCA. Dude Ranch expanded the groups audience and ...
more infohttps://itunes.apple.com/us/artist/id116851

If You Blink... : shortscarystoriesIf You Blink... : shortscarystories

They say a person blinks an average of 448,512,000 times over the span of lifetime. Apparently, that adds up to just over six ... Dont turn your back, dont look away and whatever you do dont blink... ...
more infohttps://www.reddit.com/r/shortscarystories/comments/ur8sk/if_you_blink/

blink



: Digital Photography Reviewblink : Digital Photography Review

Digital Photography Review: All the latest digital camera reviews and digital imaging news. Lively discussion forums. Vast samples galleries and the largest database of digital camera specifications.
more infohttps://www.dpreview.com/challenges/Entry.aspx?ID=679754&View=Results&Rows=4

Old Blinking Light Restaurant - Highlands Ranch, CO | OpenTableOld Blinking Light Restaurant - Highlands Ranch, CO | OpenTable

Book now at Old Blinking Light in Highlands Ranch, CO. Explore menu, see photos and read 679 reviews: We had requested a booth ... Old Blinking Light never fails to deliver. Food is always good, large menu offerings something for everyone. I dont eat meat, ... The Old Blinking Lights "Kiva Room" offers a warm, intimate atmosphere for family gatherings, corporate events, social ... With private access to an outdoor patio of Colorados beautiful front range, the Old Blinking Light is the ultimate private ...
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Old Blinking Light Restaurant - Highlands Ranch, CO | OpenTableOld Blinking Light Restaurant - Highlands Ranch, CO | OpenTable

Book now at Old Blinking Light in Highlands Ranch, explore menu, see photos and read 637 reviews: Food and service was very ... Old Blinking Light is a neighborhood treasure. Its a busy place, but service was good. I had a side of roasted Brussels sprout ... The Blinking Light is our go to eatery in Highlands Ranch. The service is usually excellent and the food is above average. ... We went to the Old Blinking Light last night. Yes, I knew they lost their liquor license for some reason, but I chose to give ...
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Blink - Audiobook | Audible.comBlink - Audiobook | Audible.com

Download the app and start listening to Blink today - Free with a 30 day Trial! Keep your audiobook forever, even if you cancel ... Blink is a book about how we think without thinking, about choices that seem to be made in an instant, in the blink of an eye, ... With his #1 best sellers, The Tipping Point, Blink and Outliers, he has reached millions of readers. And now the very best and ... With his #1 best sellers, The Tipping Point, Blink and Outliers, he has reached millions of readers. And now the very best and ...
more infohttps://www.audible.com/pd/Science-Technology/Blink-Audiobook/B002VAEK3K?ref_=pd_rsp_4&_escaped_fragment_=%2FfollowNotice%2Fclose

North Korea blinks - Foreign PolicyNorth Korea blinks - Foreign Policy

North Korea blinks. Well, it was a very exciting weekend on the Korea peninsula, as South Korea vowed to go ahead with live- ...
more infohttps://foreignpolicy.com/2010/12/20/north-korea-blinks/

Blink Steady Bike Light : gadgetsBlink Steady Bike Light : gadgets

r/gadgets: From Vintage gadgetry to the latest and greatest, /r/Gadgets is all about discussing, reviewing, and enjoying gadgets.
more infohttps://www.reddit.com/r/gadgets/comments/1c0o7f/blink_steady_bike_light/

Why We BlinkWhy We Blink

Whats more amazing than our blinking is that we stitch together the realities between blinks, so were not even aware of the ... dramatically occurs every time we blink," Tamami says. "I think that blink is closely related to resetting of the brain network ... She believes that blinking restarts the brain network.. "The present study indicates that even while we pay attention to the ... For example, why do we blink?. "Many people have extensively investigated the eye movement, but most of them did not care about ...
more infohttp://www.neatorama.com/2013/01/08/Why-We-Blink/

MCA - Family Day: BlinkMCA - Family Day: Blink

Experiment with looking, seeing, and freezing moments in time at this Family Day, inspired by the exhibition Anne Collier. Featuring projects designed and led by Family Day artists Lindsey Barlag, Jenna Deidel, Thomson Dryjanski, Corinne Mucha, and Tim Nickodemus, with special guests the
more infohttps://mcachicago.org/Calendar/2014/12/Family-Day-Blink

My eyes wont stop blinking | DailyStrengthMy eyes won't stop blinking | DailyStrength

The blinking will ease up some but is not going completely away. I had MRI done in..... ... I have had problems since May with my eyes blinking. Seams to be worse today. ... I have had problems since May with my eyes blinking. Seams to be worse today. The blinking will ease up some but is not going ...
more infohttps://www.dailystrength.org/group/multiple-sclerosis-ms/discussion/my-eyes-won-t-stop-blinking

Excessive Blinking in Children - AAPOSExcessive Blinking in Children - AAPOS

Excessive Blinking in Children. En Español Read in Chinese Why do we blink?. Blinking is a normal reflex that protects the eye ... What is excessive blinking?. Excessive blinking is blinking that seems more frequent than typical. It can involve one or both ... Blinking also regulates tears, which nourish and cleanse the surface of the eye The blinking rate in newborns is only 2 times ... What causes excessive blinking?. Excessive blinking can be caused by problems with the eyelids or anterior segment (front ...
more infohttps://aapos.org/terms/conditions/133

Blinking gives your brain a rest | HeraldNet.comBlinking gives your brain a rest | HeraldNet.com

... blinking far more often than is actually necessary to keep our eyeballs lubricated? Scientists have pried open the answer to ... Although the video gave them a blinks worth of time to rest, subjects did not recognize a breakpoint in the action, and ... WASHINGTON - Why do we spend roughly 10 percent of our waking hours with our eyes closed - blinking far more often than is ... In the seconds after telling a lie, however, the liar will blink far more frequently than a truth-teller. Perhaps the resulting ...
more infohttp://www.heraldnet.com/news/blinking-gives-your-brain-a-rest/

Smart Buildings Breathe and Blink | TreeHuggerSmart Buildings Breathe and Blink | TreeHugger

Smart Buildings Breathe and Blink. Lance Hosey, of Atmo, and Soo-in Yang and David Benjamin, of the Living, have designed ...
more infohttps://www.treehugger.com/clean-technology/smart-buildings-breathe-and-blink.html

Blink-182 (albumi) - WikipediaBlink-182 (albumi) - Wikipedia

Blink-182. 2003 Greatest Hits. 2005 Yhtyeen Blink-182 viides albumi julkaistiin nimettömänä 18. marraskuuta 2003. Levyltä ... Cheshire Cat · Dude Ranch · Enema of the State · Take off Your Pants and Jacket · Blink-182 ... Blink 182:n muut julkaisut Take off Your Pants and Jacket. 2001 ...
more infohttps://fi.wikipedia.org/wiki/Blink-182_

Blinking An LED - Extreme Edition | HackadayBlinking An LED - Extreme Edition | Hackaday

I have a really awesome valve LED blinker and the blinking is much warmer and vibrant and you can really see the quality of the ... On the subject of blinking LEDs, from reading the comments, I guess none of you are old enough to remember the LM3909? It was a ... Weve all blinked an LED. Maybe it was just to test a microcontroller, like the simplest Arduino example. ... The point here is not blinking an LED, it is about designing LSI at home and beeing able get it manufactured at affordable cost ...
more infohttps://hackaday.com/2016/10/13/blinking-an-led-extreme-edition/?replytocom=3231800

Blinking An LED - Extreme Edition | HackadayBlinking An LED - Extreme Edition | Hackaday

I have a really awesome valve LED blinker and the blinking is much warmer and vibrant and you can really see the quality of the ... On the subject of blinking LEDs, from reading the comments, I guess none of you are old enough to remember the LM3909? It was a ... Weve all blinked an LED. Maybe it was just to test a microcontroller, like the simplest Arduino example. ... The point here is not blinking an LED, it is about designing LSI at home and beeing able get it manufactured at affordable cost ...
more infohttps://hackaday.com/2016/10/13/blinking-an-led-extreme-edition/?replytocom=3232899

blink-182 - Whats My Age Again? - YouTubeblink-182 - What's My Age Again? - YouTube

Listen to more from Blink-182: https://lnk.to/Blink182 Discover more about this classic song and the Enema Of The State album ... BLINK - 182 Greatest Hits ,, BLINK - 182 Best Songs Collection - Duration: 1:14:16. Punk Rock 136,343 views ... blink-182 - All The Small Things (Official Video) - Duration: 2:53. blink-182 233,272,738 views ... blink-182 - I Miss You (Official Video) - Duration: 3:50. blink-182 236,415,239 views ...
more infohttps://www.youtube.com/watch?v=K7l5ZeVVoCA

SOLVED: Immobilizer light stops blinking - FixyaSOLVED: Immobilizer light stops blinking - Fixya

immobilizer light stops blinking Hi all, i have 06 monster and lately , ive found out that in the morning when i go - Ducati ... Re: immobilizer light stops blinking. I dont think you need to worry. According to my manual (S2R 1K) the immobilizer light ... ive found out that in the morning when i go start the bike the immobilizer light is however not blinking as usual,its been ... the engine wouldnt start and the immobilizer light would stay on for a few seconds before disappearing without blinking.Any ...
more infohttp://www.fixya.com/motorcycles/t1270986-ducati_monster_1000s_immobilizer_light
  • Most eye movement researchers have dismissed blinking simply as an involuntary way to lubricate the eyes, but that is not what Nakano believes. (neatorama.com)
  • An earlier study had shown the researchers which implicit breakpoints in the "Mr. Bean" video most commonly elicited a spontaneous blink, so researchers knew when to look for changes in the brain's activation patterns. (heraldnet.com)
  • Sure enough, when subjects blinked, the researchers detected a momentary stand-down within the brain's visual cortex and somatosensory cortex - both involved with processing visual stimuli - and in areas that govern attention. (heraldnet.com)
  • In a separate experiment, the researchers established that the momentary rest that blinking appears to represent is a deliberate act, and not just a response to an absence of stimuli. (heraldnet.com)
  • Use Blink Contacts® to lubricate and rewet soft and rigid gas permeable (RGP) contact lenses as well as to cushion lenses prior to application. (walgreens.com)
  • following blink onset, cortical activity decreases in the dorsal network and increases in the default-mode network, associated with internal processing. (wikipedia.org)
  • Jerry Finn pour les chants extraits des albums Enema Of The State ' , The Mark, Tom, and Travis Show: The Enema Strikes Back , Take Off Your Pants And Jacket , Blink-182 ainsi que le titre Not Now . (wikipedia.org)
  • A reflex blink occurs in response to an external stimulus, such as contact with the cornea or objects that appear rapidly in front of the eye. (wikipedia.org)
  • Voluntary blink is larger amplitude than Reflex blink, with the use of all 3 divisions of the orbicularis oculi muscle. (wikipedia.org)
  • Reflex blink may occur in response to tactile stimuli (e.g. corneal, eyelash, skin of eyelid, contact with eyebrow), optical stimuli (e.g. dazzle reflex, or menace reflex) or auditory stimuli (e.g., menace reflex) Voluntary blink is larger amplitude than Reflex blink, with the use of all 3 divisions of the orbicularis oculi muscle. (wikipedia.org)
  • The crash prompted Hoppus and DeLonge to reconnect with the drummer in support of his recovery, and in 2009 blink-182 announced that they were reuniting, hitting the road with Weezer for their reunion tour. (apple.com)
  • except now the battery light on my laptop blinks green once then yellow three times and then repeats over. (experts-exchange.com)
  • subject blinked during a slow shutter speed,available light exposure, Honest! (dpreview.com)
  • Whether you are looking for a relaxing lunch, family-friendly dinner or night out to enjoy excellent margaritas, the Old Blinking Light welcomes you! (opentable.com)
  • With private access to an outdoor patio of Colorado's beautiful front range, the Old Blinking Light is the ultimate private dining experience in Highlands Ranch. (opentable.com)
  • Hi all, i have 06 monster and lately , i've found out that in the morning when i go start the bike the immobilizer light is however not blinking as usual,it's been few times already and then i was afraid that the battery's dead which is unlikely then i start the engine , and fortunately it's alright, the battery's good. (fixya.com)
  • This morning the engine wouldn't start and the immobilizer light would stay on for a few seconds before disappearing without blinking.Any idea what the problem could be? (fixya.com)
  • Blinking may have other functions since it occurs more often than necessary just to keep the eye lubricated. (wikipedia.org)
  • The present study indicates that even while we pay attention to the external world, the shift from the external attentional brain network to the internal processing brain network (default mode network) dramatically occurs every time we blink," Tamami says. (neatorama.com)
  • the yellow lights blink really fast then the green blinks slow. (experts-exchange.com)
  • The threat of a lawsuit from a similarly named Irish band forced them to change their name to blink-182, but that did not slow them down: the group earned a higher profile by touring the world with Pennywise and NOFX on the 1996-1997 Warped Tour, in addition to appearing on innumerable skate/surf/snowboarding videos. (apple.com)
  • To stop the cornea at the front of the eye from drying out, our eyelid spreads tear fluid on the eye surface to keep it moist whenever we blink - something we typically do approximately 15 to 20 times a minute. (zeiss.com)
  • A newborn baby only blinks about twice a minute, while somebody who is flustered or tense might blink up to 50 times a minute. (zeiss.com)
  • Our blink frequency also changes when we read or watch television, dropping to a rate of around seven times a minute. (zeiss.com)
  • I am afraid to open the application, knowing that it may take days of my life to reemerge, blinking and shambling, into the sunlight. (metafilter.com)
  • The amount we blink differs from one person to the next. (zeiss.com)
  • A person may be watching Mr. Bean in the default mode network, but when they become visually more attentive they will blink and switch to the dorsal attention network. (neatorama.com)
  • This hacker's video on blinking LEDs never got the recognition it deserves. (hackaday.com)
  • Music video by blink-182 performing What's My Age Again? (youtube.com)
  • This type of blinking is conducted in the pre-motor brain stem and happens without conscious effort, like breathing and digestion . (wikipedia.org)
  • Did you know that when we blink our brain blocks visual perception for just a fraction of a second? (zeiss.com)
  • She believes that blinking restarts the brain network. (neatorama.com)
  • Her study shows that blinking is like shifting gears between two different networks in the brain. (neatorama.com)
  • Originally known as simply Blink, the band debuted in 1993 with a self-released EP, Fly Swatter. (apple.com)
  • The duration of a blink is on average 100-150 milliseconds according to UCL researcher and between 100-400 ms according to the Harvard Database of Useful Biological Numbers. (wikipedia.org)
  • Excessive blinking can be caused by problems with the eyelids or anterior segment (front surface of the eye), habitual tics, refractive error (need for glasses), intermittent exotropia or turning out of the eye, and stress. (aapos.org)
  • Humans use winking , the blinking of only one eye, as a form of body language . (wikipedia.org)
  • Though the current study didn't examine the relationship between blinking and deception, others have: While telling a lie, liars have been found to blink less - possibly because the act of deception requires rapt and uninterrupted attention to pull it off. (heraldnet.com)
  • Glasses may be prescribed if the excessive blinking is caused by blurry vision. (aapos.org)
  • It is very rare for excessive blinking to be a sign of an undiagnosed neurologic disorder. (aapos.org)
  • while watching a movie, for instance, we're most likely to blink when an actor turns to leave the scene or when the camera shifts to follow the dialogue. (heraldnet.com)
  • Many people have extensively investigated the eye movement, but most of them did not care about the eye blink," writes Tamami Nakano, as associate professor at Osaka University in Japan, in an email. (neatorama.com)
  • the blink is thought to help the eye shift its target point. (wikipedia.org)
  • With his #1 best sellers, The Tipping Point , Blink and Outliers , he has reached millions of readers. (audible.com)
  • The point here is not blinking an LED, it is about designing LSI at home and beeing able get it manufactured at affordable cost. (hackaday.com)
  • A single blink is determined by the forceful closing of the eyelid or inactivation of the levator palpebrae superioris and the activation of the palpebral portion of the orbicularis oculi , not the full open and close. (wikipedia.org)
  • At a time when competition with teen pop and nu-metal were not unheard of, blink-182 released a steady stream of hits, bolstered by humorous, tongue-in-cheek music videos that were popular in the waning days of MTV's musical programming. (apple.com)
  • The blinking rate is determined by the "blinking center", but it can also be affected by external stimulus. (wikipedia.org)
  • Greater activation of dopaminergic pathways dopamine production in the striatum is associated with a higher rate of spontaneous eye blinking. (wikipedia.org)
  • Birds, reptiles and sharks blink with a nictitating membrane from one side of the eye to the other. (wikipedia.org)