Blastomycosis
A fungal infection that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.
Blastomyces
Lung Diseases, Fungal
Central Nervous System Fungal Infections
MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME).
Histoplasmosis
Itraconazole
Coccidioidomycosis
Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.
Antifungal Agents
Paracoccidioidomycosis
Blastomycosis acquired occupationally during prairie dog relocation--Colorado, 1998. (1/191)
On August 31, 1998, two suspected cases of fungal pneumonia were reported to the Boulder County (Colorado) Health Department (BCHD). Both patients were immunocompetent, otherwise healthy adults working for the City of Boulder Open Space (CBOS) program on a prairie dog relocation project. This report summarizes the epidemiologic investigation by BCHD, the Colorado Department of Public Health and Environment, and CDC; the findings indicate that these two persons acquired blastomycosis in Colorado, which is outside the area where the disease is endemic. (+info)Targeted gene disruption reveals an adhesin indispensable for pathogenicity of Blastomyces dermatitidis. (2/191)
Systemic fungal infections are becoming more common and difficult to treat, yet the pathogenesis of these infectious diseases remains poorly understood. In many cases, pathogenicity can be attributed to the ability of the fungi to adhere to target tissues, but the lack of tractable genetic systems has limited progress in understanding and interfering with the offending fungal products. In Blastomyces dermatitidis, the agent of blastomycosis, a respiratory and disseminated mycosis of people and animals worldwide, expression of the putative adhesin encoded by the WI-1 gene was investigated as a possible virulence factor. DNA-mediated gene transfer was used to disrupt the WI-1 locus by allelic replacement, resulting in impaired binding and entry of yeasts into macrophages, loss of adherence to lung tissue, and abolishment of virulence in mice; each of these properties was fully restored after reconstitution of WI-1 by means of gene transfer. These findings establish the pivotal role of WI-1 in adherence and virulence of B. dermatitidis yeasts. To our knowledge, they offer the first example of a genetically proven virulence determinant among systemic dimorphic fungi, and underscore the value of reverse genetics for studies of pathogenesis in these organisms. (+info)Endemic mycoses: a treatment update. (3/191)
Endemic mycoses remain a major public health problem in several countries and they are becoming increasingly frequent with the spread of HIV infection. Amphotericin B remains the drug of choice during the acute stage of life-threatening endemic mycoses occurring in both immunocompetent and immunocompromised hosts. Ketoconazole is effective in non-AIDS patients with non-life-threatening histoplasmosis, blastomycosis, or paracoccidioidomycosis. Itraconazole is the treatment of choice for non-life-threatening Histoplasma capsulatum or Blastomyces dermatitidis infections occurring in immunocompetent individuals and is the most efficient secondary prophylaxis of histoplasmosis in AIDS patients. Itraconazole is also effective in lymphocutaneous and visceral sporotrichosis, in paracoccidioidomycosis, for Penicillum marneffei infection, and is an alternative to amphotericin B for Histoplasma duboisii infection. Coccidioidomycosis may be effectively treated with prolonged and sometimes life-long itraconazole or fluconazole therapy. Fluconazole has relatively poor efficacy against histoplasmosis, blastomycosis and sporotrichosis. New antifungal agents have been tested in vitro or in animal models and may soon be evaluated in clinical trials. (+info)Thoracic blastomycosis and empyema. (4/191)
Blastomycosis is endemic in river valley areas of the southeastern and Midwestern United States. Pulmonary manifestations include chronic cough and pleuritic pain. Radiographic appearance of the infection can mimic bronchogenic lung carcinoma. Pleural effusion is rarely associated with this pulmonary infection, and empyema has not been previously reported. We report a case of pulmonary and pleural Blastomyces dermatitidis infection presenting as empyema thoracis. Diagnosis and treatment were attained with video-assisted thoracoscopic (VATS) pleural and lung biopsy and debridement. (+info)Disseminated blastomycosis in a rhesus monkey (Macaca mulatta). (5/191)
An 8-year-old male rhesus monkey (Macaca mulatta) died following a 6-day illness consisting of progressive depression, anorexia, labored abdominal breathing, coughing, and tachypnea. Gross necropsy findings included severe multifocal (miliary) granulomatous pneumonia, granulomatous splenitis, and multifocal cerebral abscesses. Histologic examination revealed 10-15-microm broad-based budding organisms within pyogranulomatous inflammatory lesions in the lung, tracheobronchial lymph node, brain, spleen, and liver. The distribution of extrapulmonary lesions was intermediate between that described for dogs and that described for humans. These findings were consistent with blastomycosis, which is previously unreported in nonhuman primates. (+info)T-Cell epitopes and human leukocyte antigen restriction elements of an immunodominant antigen of Blastomyces dermatitidis. (6/191)
Humans infected with the dimorphic fungus Blastomyces dermatitidis develop strong T-lymphocyte responses to WI-1, an immunodominant antigen that has been shown to elicit protective immunity in mice. In the present study, the T-cell epitopes of WI-1 and human leukocyte antigen (HLA) restricting elements that display them were investigated. Peripheral blood mononuclear cells (PBMC) from 37 patients with a confirmed history of blastomycosis were tested for a response to WI-1 in primary proliferation assays; PBMC from 35 (95%) responded. Six patients whose PBMC proliferated strongly in response to WI-1 (defined as a stimulation index greater than 50) were tested further for responses to subcloned, recombinant fragments of the antigen. These patients responded chiefly to sequences within the N terminus and the 25-amino-acid tandem repeat. Cloned CD4(+) T cells from an infected individual were used to delineate more precisely the peptide epitopes in the fragments and HLA restricting elements that present them. A majority of the T-cell clones recognized an epitope spanning amino acids 149 to 172 within the N terminus, displayed by HLA-DR 15. A minority of the clones, which have been shown to perform a cytolytic function in vitro, recognized an epitope in the tandem repeat displayed by HLA-DPw4, an uncommon restricting element. Tandem repeat epitopes required display by the beta chain of DPw4 heterodimers. Thus, human T cells with different functions in vitro also recognize distinct regions of WI-1, raising the possibility that HLA restricting elements that present them could modulate immunity during blastomycosis by selection and display of WI-1 peptides. (+info)Jorge Lobo's disease: experimental inoculation in Swiss mice. (7/191)
Sixty-four isogenic Swiss mice were intradermically inoculated in both hind foot pads. The inocula, consisting of fungal suspensions from biopsies obtained from Jorge Lobo's Disease patients, had the total number of fungi and the viability index determined using a Neubauer chamber and the fluorescein diacetate-ethidium bromide technique (FD-EB), respectively. The animals were sacrificed at times ranging from ten days to eighteen months after inoculation. The cellular infiltrate, mainly consisting of macrophages containing fungi, increased progressively up to end of the study; however, no macroscopic alterations were observed in the inoculated feet. After nine months, small numbers of Langhans' giant cells started to appear in the infiltrate. A considerable number of fungi was observed at the end of the experimental period, but only a few were viable when stained by the FD-EB technique. This fact suggests that there is a multiplication of fungal cells, which are destroyed by the macrophages but remain in the tissue for a long time due perhaps to the difficulties in their elimination. These findings led us to conclude that in spite of the maintenance of the infection in these animals, Swiss mice cannot be considered an ideal model to study Jorge Lobo's Disease. However, the authors call attention to the possibility of other mouse strains being more susceptible to Paracoccidioides loboi. (+info)Molecular epidemiology of Blastomyces dermatitidis. (8/191)
The inhalation of conidia of Blastomyces dermatitidis, a fungus found in soil, causes disease in humans and animals. We studied the genetic diversity of this pathogen by extracting DNA yeasts and analyzing them with a polymerase chain reaction (PCR)-based typing system we developed, which used restriction fragment analysis of amplicons from the regions between the rDNA repeats and allowed us to class isolates into 3 major groups. Strains were further differentiated by use of PCR fingerprinting with 3 different primers. Fifty-nine isolates collected over 35 years from 15 regions (United States, India, Africa, Canada) were analyzed. Genotypic groups A, B, and C contained 17, 23, and 19 isolates, which were divided into 5, 15, and 12 types, respectively. All 16 isolates from North America in group A were from the upper midwestern United States or Canada, whereas 0 of 20 isolates from the southeastern United States were in group A. Studies of the largest collection from 1 locale (Eagle River, WI), revealed that the soil isolates studied were not responsible for the majority of cases in this outbreak, as previously proposed, and that >1 strain was present in the environment and in patients. Overall, these results provide a tool for the epidemiological study of blastomycosis and illuminate the genetic and geographic diversity of this important pathogen. (+info) Blastomycosis is a rare, fungal infection caused by Blastomyces dermatitidis, which primarily affects the lungs and skin. The infection is endemic in certain regions of North America, particularly in areas with high humidity and temperate climates.
The fungus is found in soil and water and is typically contracted through the inhalation of contaminated dust or the ingestion of contaminated food or water. The symptoms of blastomycosis can vary depending on the severity of the infection, but may include:
* Fever
* Cough
* Shortness of breath
* Skin lesions
* Joint pain
* Swollen lymph nodes
In severe cases, blastomycosis can lead to life-threatening complications such as respiratory failure, cardiovascular problems, and meningitis.
Diagnosis of blastomycosis is based on a combination of clinical findings, laboratory tests, and imaging studies. Treatment typically involves antifungal medications, which can be effective in resolving symptoms and preventing complications. However, the disease can be challenging to diagnose and treat, and long-term follow-up is often necessary to ensure that the infection has been fully cleared.
Preventive measures for blastomycosis include avoiding contact with contaminated soil and water, wearing protective clothing and equipment when working outdoors in areas where the fungus is prevalent, and taking antifungal medications as prescribed by a healthcare provider. Early diagnosis and treatment are critical to preventing severe complications and improving outcomes for patients with blastomycosis.
Fungal lung diseases refer to a group of conditions that affect the lungs and are caused by fungal infections. These infections can be acute or chronic, and can range from mild to severe.
Types of fungal lung diseases include:
1. Aspergillosis: This is an infection caused by the fungus Aspergillus, which is commonly found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with cancer, HIV/AIDS, or taking immunosuppressive drugs.
2. Cryptococcosis: This is an infection caused by the fungus Cryptococcus neoformans, which is found in soil and decaying wood. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
3. Histoplasmosis: This is an infection caused by the fungus Histoplasma capsulatum, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
4. Pneumocystis pneumonia (PCP): This is an infection caused by the fungus Pneumocystis jirovecii, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
5. Sporotrichosis: This is an infection caused by the fungus Sporothrix schenckii, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
Symptoms of fungal lung diseases can include:
* Cough
* Fever
* Chest pain
* Shortness of breath
* Fatigue
Diagnosis of fungal lung diseases is typically made through a combination of physical examination, medical history, and laboratory tests such as chest X-rays, CT scans, and fungal cultures. Treatment usually involves antifungal medications and may also include supportive care to manage symptoms.
Prevention of fungal lung diseases includes:
1. Avoiding exposure to fungal spores by wearing protective clothing and gear when working with soil or decaying organic matter.
2. Maintaining good indoor air quality by using ventilation systems and reducing humidity.
3. Reducing the risk of infection by avoiding close contact with people who are at high risk of developing fungal lung diseases, such as those with weakened immune systems.
4. Avoiding smoking and other tobacco products, which can increase the risk of developing fungal lung diseases.
5. Managing underlying medical conditions, such as HIV/AIDS or taking immunosuppressive drugs, to reduce the risk of developing fungal lung diseases.
Central nervous system (CNS) fungal infections refer to infections caused by fungi that affect the brain and spinal cord. These infections can be serious and potentially life-threatening, and are more common in people with compromised immune systems or underlying medical conditions.
The most common types of CNS fungal infections include:
1. Meningitis: An inflammation of the membranes that cover the brain and spinal cord, caused by fungi such as Candida, Aspergillus, or Cryptococcus.
2. Encephalitis: An inflammation of the brain tissue itself, caused by fungi such as Histoplasma or Coccidioides.
3. Abscesses: Pocket of pus that form in the brain or spinal cord, caused by bacteria or fungi.
4. Opportunistic infections: Infections that occur in people with compromised immune systems, such as HIV/AIDS patients or those taking immunosuppressive drugs after an organ transplant.
CNS fungal infections can cause a wide range of symptoms, including headache, fever, confusion, seizures, and loss of coordination. They are typically diagnosed through a combination of physical examination, laboratory tests, and imaging studies such as CT or MRI scans.
Treatment of CNS fungal infections usually involves the use of antifungal medications, which can be administered intravenously or orally. The choice of treatment depends on the severity and location of the infection, as well as the patient's overall health status. In some cases, surgery may be necessary to drain abscesses or relieve pressure on the brain.
Prevention of CNS fungal infections is important for individuals at risk, such as those with compromised immune systems or underlying medical conditions. This includes taking antifungal medications prophylactically, avoiding exposure to fungal spores, and practicing good hygiene.
Overall, CNS fungal infections are serious and potentially life-threatening conditions that require prompt diagnosis and treatment. With appropriate management, many patients can recover fully, but delays in diagnosis and treatment can lead to poor outcomes.
Histoplasmosis is a fungal disease caused by Histoplasma capsulatum, which primarily affects the lungs and can disseminate to other organs. It occurs when spores of the fungus are inhaled, usually after exposure to contaminated soil or bird droppings. The symptoms of histoplasmosis range from mild to severe and include fever, cough, chest pain, fatigue, and difficulty breathing. Diagnosis is based on clinical findings, laboratory tests, and imaging studies. Treatment is primarily supportive, including antifungal medications for severe cases. Prevention includes avoiding exposure to contaminated environments and wearing protective clothing during cleanup or construction activities. Histoplasmosis has a global distribution and can be found in many parts of the United States, particularly in areas with high humidity and bird droppings. It is an important occupational hazard for workers involved in construction, mining, and agriculture.
Here are 10 key points to remember about histoplasmosis:
1) Histoplasmosis is a fungal disease caused by Histoplasma capsulatum.
2) It primarily affects the lungs and can disseminate to other organs.
3) Inhalation of spores from contaminated soil or bird droppings leads to infection.
4) Symptoms range from mild to severe, including fever, cough, chest pain, fatigue, and difficulty breathing.
5) Diagnosis is based on clinical findings, laboratory tests, and imaging studies.
6) Treatment is primarily supportive, with antifungal medications for severe cases.
7) Prevention includes avoiding exposure to contaminated environments and wearing protective clothing during cleanup or construction activities.
8) Histoplasmosis has a global distribution and is found in many parts of the United States.
9) It is an important occupational hazard for workers involved in construction, mining, and agriculture.
10) In severe cases, histoplasmosis can lead to chronic lung disease, heart problems, and meningitis.
Coccidioidomycosis, also known as valley fever, is a fungal infection caused by Coccidioides immitis and Coccidioides posadasii. These fungi are found in soil and decaying organic matter in certain regions of the southwestern United States and northern Mexico. The infection is typically acquired through inhalation of fungal spores, which can be present in dust or soil.
The symptoms of coccidioidomycosis can vary depending on the severity of the infection and the individual's immune response. Some people may experience mild symptoms, such as fever, cough, and fatigue, while others may develop more severe symptoms, including pneumonia, meningitis, and bone or skin infections. Skin lesions and rashes are also common.
Diagnosis of coccidioidomycosis typically involves a combination of physical examination, laboratory tests, and imaging studies. Treatment may involve antifungal medications and supportive care to manage symptoms. In severe cases, hospitalization may be necessary.
Prevention is key in avoiding coccidioidomycosis, which includes avoiding areas with high concentrations of the fungus, using respiratory protection when working in areas where the fungus is present, and taking antifungal medications prophylactically for those who are at high risk.
Prognosis for coccidioidomycosis is generally good for those with mild infections, but can be poor for those with severe infections or underlying conditions such as HIV/AIDS or cancer. Long-term effects of the infection can include lung scarring and joint damage.
Dermatomycoses: a superficial fungal infection of the skin, often caused by species of Trichophyton or Epidermophyton. Characterized by inflammation, itching, scaling, and crusting of affected areas. Treatment with antifungal medications is usually effective. Also called ringworm.
Also found in: Medical, Encyclopedia.
Examples from the web for 'dermatomycoses'
Some common types of dermatomycoses include athlete's foot and jock itch.
Scientific American, 25 Mar. 2019.
Topical antifungal medications are effective against most types of dermatomycoses.
Britannica.com: encyclopedia article about dermatomycoses.
This condition is caused by a type of fungus that affects the skin, known as dermatomycoses.
Mayo Clinic, 01 Mar. 2020.
Paracoccidioidomycosis is a rare, chronic and progressive systemic fungal infection caused by the dimorphic fungus Paracoccidioides spp., which primarily affects the lungs and mucocutaneous tissues. It is endemic in certain regions of South America, particularly in Brazil, Argentina, and Venezuela.
The disease typically presents with symptoms such as fever, cough, fatigue, weight loss, and night sweats, and can progress to severe respiratory, cutaneous, and disseminated forms if left untreated. The infection is diagnosed through a combination of clinical evaluation, radiological studies, and laboratory tests such as PCR and culture.
Treatment options for paracoccidioidomycosis include antifungal medications such as amphotericin B, fluconazole, and itraconazole, which are often associated with significant side effects and variable efficacy. Surgical debulking may also be considered in certain cases.
The prognosis for paracoccidioidomycosis is generally poor, especially in advanced stages of the disease, with high rates of morbidity and mortality. However, early diagnosis and appropriate treatment can improve outcomes.
Blastomycosis
... was first described by Thomas Caspar Gilchrist in 1894, as a skin disease. Because of this, blastomycosis is ... Less frequently, blastomycosis also occurs in Africa, the Middle East, India, and western North America. Blastomycosis also ... However, the overall risk of blastomycosis in cats is 28 to 100 times lower than in dogs. Cases of blastomycosis have also been ... Although blastomycosis is especially dangerous for those with weak immune systems, most people diagnosed with blastomycosis ...
Blastomycosis-like pyoderma
... is a cutaneous condition characterized by large verrucous plaques with elevated borders and ... multiple pustules.: 255, 272 List of cutaneous conditions pyoderma blastomycosis Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo ...
Cold abscess
Ferri, Fred (2015). "Blastomycosis". Ferri's Clinical Advisor. Philadelphia: Mosby (Elsevier). pp. 198.e2-198.e4. ISBN ... which cause blastomycosis, that do not tend to stimulate acute inflammation. Alternatively, cold abscesses are typical in ...
Rhoda Williams Benham
With F. C. Bocobo.) Cryptococcosis and blastomycosis. Ann. New York Acad. Sci. 50: 1299-1314. 1950. The Laboratory of Medical ... Hopkins.) The fungi of blastomycosis and coccidioidal granuloma. Arch. Derm. Syph. 30: 385-400. 1934. The terminology of the ... Benham, Rhoda W. (September 1950). "CRYPTOCOCCOSIS AND BLASTOMYCOSIS". Annals of the New York Academy of Sciences. 50 (10): ...
Blastomyces dermatitidis
Dwight, P.J.; Naus, M; Sarsfield, P; Limerick, B (2000). "An outbreak of human blastomycosis: the epidemiology of blastomycosis ... Blastomycosis is generally readily treatable with systemic antifungal drugs once it is correctly diagnosed; however, delayed ... The Canadian range of B. dermatitidis shows an abundance of blastomycosis in broad areas north and south of the St. Lawrence ... The internal organs of the mice are then checked microscopically for evidence of blastomycosis. Needless to say, the cost and ...
Richard Summerbell
February 2006). "Blastomycosis in Ontario, 1994-2003". Emerging Infectious Diseases. 12 (2): 274-9. doi:10.3201/eid1202.050849 ... lakes or rivers that infect otherwise healthy visitors with the often deadly disease blastomycosis. His most cited works are on ...
Periodontal disease
Crich A (June 1932). "Blastomycosis of the Gingiva and Jaw". Canadian Medical Association Journal. 26 (6): 662-5. PMC 402380. ...
Paracoccidioidomycosis
North American blastomycosis James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2019). "13 ... Paracoccidioidomycosis (PCM), also known as South American blastomycosis, is a fungal infection that can occur as a mouth and ...
Albert Balows
Furcolow, Michael L.; Balows, A.; Menges, R. W.; Pickar, D.; McClellan, J. T.; Saliba, A. (1966). "Blastomycosis: An important ... "Some Factors Affecting Survival in Systemic Blastomycosis". Diseases of the Chest. 54: 285-291. doi:10.1378/chest.54.Supplement ...
Dog health
Blastomycosis, caused by Blastomyces species including Blastomyces dermatitidis, is a fungal disease that affects both dogs and ... Probst, Sarah (1999). "Blastomycosis-Fungal Disease Common in Outdoor Dogs". Pet Columns. UIUC College of Veterinary Medicine. ...
Acid-fastness
... of fungi in blastomycosis and histoplasmosis. Arch Pathol Lab Med 1982; 106:440-41. Ziehl-Neelsen protocol (PDF ...
Itraconazole
This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by ... It is also licensed for use in blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis. Itraconazole is over 99% ...
Pseudomonal pyoderma
Blastomycosis-like pyoderma List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). ...
Emergency management
Fungal infections may lead to chromoblastomycosis, blastomycosis, mucormycosis, and dermatophytosis. Other numerous arthropod, ...
Fluconazole
This includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis ...
Lorraine Friedman
... the cause of North American blastomycosis, and blastomyces brasiliensis, the cause of South American blastomycosis." A portion ... the cause of North American blastomycosis, and blastomyces brasiliensis, the cause of South American blastomycosis (PhD). Duke ... Friedman, L; Conant, N.F. (1953). "Immunological studies on the etiologic agents of North and South American blastomycosis". ... of her research, "Immunological studies on the etiologic agents of North and South American blastomycosis" was published in ...
Paracoccidioides brasiliensis
Restrepo, M; Restrepo A (1970). "Paracoccidiomycosis (South American blastomycosis): a study of 39 cases observed in Medellin, ... The pathological features of paracoccidioidomycosis are similar to those seen in coccidioidomycosis and blastomycosis. However ... Blastomycosis dermatitidis. The yeast-like form of P. brasiliensis contains multiple nuclei, a porous two-layered nuclear ... bone and prostate set the clinical picture of paracoccidioidomycosis apart from that of blastomycosis. Martinez, Roberto; ...
Histoplasma capsulatum
Histoplasmosis, like blastomycosis, may disseminate haematogenously to infect internal organs and tissues, but it does so in a ... Unlike blastomycosis, histoplasmosis is a recognized AIDS-defining illness in people with HIV infection; disseminated ...
Rickettsia
In his early part of career, he undertook research at Northwestern University on blastomycosis. He later worked on Rocky ...
Fever of unknown origin
Endemic mycoses such as histoplasmosis, blastomycosis, coccidiomycosis and paracoccidioidomycosis can cause a fever of unknown ... Disseminated granulomatoses such as tuberculosis, histoplasmosis, coccidioidomycosis, blastomycosis and sarcoidosis are ...
Fungal meningitis
Meningitis is an unusual manifestation of blastomycosis and can be very difficult to diagnose. Cryptococcus (Cryptococcal ...
Fungal infection
Some types such as blastomycosis, cryptococcus, coccidioidomycosis and histoplasmosis, affect people who live or visit certain ... Some fungal infections such as coccidioidomycosis, histoplasmosis, and blastomycosis can present with fever, cough, and ... ICD-11 codes include: 1F20 Aspergillosis 1F21 Basidiobolomycosis 1F22 Blastomycosis 1F23 Candidosis 1F24 Chromoblastomycosis ... Systemic fungal infections include histoplasmosis, cryptococcosis, coccidioidomycosis, blastomycosis, mucormycosis, ...
Howard Taylor Ricketts
In the early part of his career, Ricketts undertook research at Northwestern University on blastomycosis. He later worked in ...
List of dog diseases
Blastomycosis* is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans. Dogs are ten times ...
Granuloma
... blastomycosis, and cat-scratch disease. Examples of noninfectious granulomatous diseases are sarcoidosis, Crohn's disease, ... and granulomas with numerous neutrophils suggest blastomycosis, granulomatosis with polyangiitis, aspiration pneumonia, or cat- ...
Tuberculosis verrucosa cutis
In this phase, it can be confused with fungal infections such as blastomycosis and chromoblastomycosis.[citation needed] The ...
Emmonsiosis
Other conditions that appear similar include tuberculosis, blastomycosis, sporotrichosis, chicken pox, Kaposi's sarcoma and ...
Mouth ulcer
"North American Blastomycosis"). Entamoeba histolytica, a parasitic protozoan, is sometimes known to cause mouth ulcers through ...
Amphotericin B
The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, ...
Lobomycosis
Other names which were given to the disease are: keloidal blastomycosis, Amazonian blastomycosis, blastomycoid granuloma, ...
Blastomycosis | Fungal Diseases | CDC
Blastomycosis definition, symptoms, risk and prevention, sources of infection, diagnosis, treatment, information for healthcare ... Blastomycosis is an infection caused by a fungus called Blastomyces. The fungus lives in the environment, particularly in moist ... People can get blastomycosis after breathing in the microscopic fungal spores from the air. Although most people who breathe in ...
Blastomycosis: MedlinePlus Medical Encyclopedia
Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. The fungus is found in decaying wood ... You can get blastomycosis by contact with moist soil, most commonly where there is rotting wood and leaves. The fungus enters ... Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. The fungus is found in decaying wood ... Blastomycosis is rare. It is found in the central and southeastern United States, and in Canada, India, Israel, Saudi Arabia, ...
Blastomycosis - PubMed
Blastomycosis is an endemic mycoses in the central United States caused by a dimorphic fungus, Blastomyces dermatitidis, that ... Blastomycosis. Mazi PB, Rauseo AM, Spec A. Mazi PB, et al. Infect Dis Clin North Am. 2021 Jun;35(2):515-530. doi: 10.1016/j.idc ... Blastomycosis Robert W Bradsher et al. Infect Dis Clin North Am. 2003 Mar. ... Pulmonary blastomycosis. Bariola JR, Vyas KS. Bariola JR, et al. Semin Respir Crit Care Med. 2011 Dec;32(6):745-53. doi: ...
Blastomycosis - PubMed
Blastomycosis is an endemic mycoses in the central United States caused by a dimorphic fungus, Blastomyces dermatitidis, that ... Blastomycosis. Mazi PB, Rauseo AM, Spec A. Mazi PB, et al. Infect Dis Clin North Am. 2021 Jun;35(2):515-530. doi: 10.1016/j.idc ... Blastomycosis Robert W Bradsher et al. Infect Dis Clin North Am. 2003 Mar. ... Pulmonary blastomycosis. Bariola JR, Vyas KS. Bariola JR, et al. Semin Respir Crit Care Med. 2011 Dec;32(6):745-53. doi: ...
Etymologia: Blastomycosis - Volume 20, Number 11-November 2014 - Emerging Infectious Diseases journal - CDC
Blastomycosis [blasʺto-mi-koʹsis]. From the Greek blastós ("germ, sprout") and mykēs ("fungus, mushroom"), this invasive fungal ... Clinical and laboratory update on blastomycosis. Clin Microbiol Rev. 2010;23:367-81 . DOIPubMedGoogle Scholar ... Etymologia: Blastomycosis. Volume 20, Number 11-November 2014. Article Views: 205. Data is collected weekly and does not ... Henry R. Etymologia: Blastomycosis. Emerging Infectious Diseases. 2014;20(11):1794. doi:10.3201/eid2011.et2011.. ...
Webinar Thursday, September 21, 2023 - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and...
The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that ... Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of ... Calls/Webinars - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis​, Thursday ... Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis. *Preparing for the ...
Webinar Thursday, September 21, 2023 - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and...
The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that ... Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of ... Calls/Webinars - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis​, Thursday ... Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis. *Preparing for the ...
Blastomycosis : Treatment - Health32
SUPPLEMENTARY FIGURE 3. Estimated geographic range of blastomycosis
Surveillance for Coccidioidomycosis, Histoplasmosis, and Blastomycosis - United States, 2019 Cite CITE. Title : Surveillance ... Centers for Disease Control and Prevention (U.S.) (2022). SUPPLEMENTARY FIGURE 3. Estimated geographic range of blastomycosis. ... Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY FIGURE 3. Estimated geographic range of blastomycosis" (2022) ... Title : SUPPLEMENTARY FIGURE 3. Estimated geographic range of blastomycosis Corporate Authors(s) : Centers for Disease Control ...
Blastomycosis| CDC
Fungal Disease-Specific Research | NIH: National Institute of Allergy and Infectious Diseases
Blastomycosis Archives - Patient Worthy
Blastomycosis Outbreak Found in Paper Mill Workers in Michigans Upper Peninsula *Post author:Jessica Lynn ... Post category:Blastomycosis/Timely. At the end of February 2023, workers at the Escanaba Billerud Paper Mill began feeling ill ... Post category:Blastomycosis. According to a publication from the University of Wisconsin-Madison, analysis of a large outbreak ... Researchers Propose Genetic Link to Hmongs Susceptibility to Blastomycosis *Post author:Scott Carlson ...
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Blastomycosis: Blastomyces dermatitidis. Blastomycosis is endemic in the Ohio and Mississippi River valley, around the Great ... Blastomycosis. A) Gross specimen of lung with a large yellow nodule in the upper lobe. B) H&E section of the mass with multiple ... Blastomycosis. A) Gross specimen of lung with a large yellow nodule in the upper lobe. B) H&E section of the mass with multiple ... Acute blastomycosis of the lung is a suppurative infection with infiltration of neutrophils and abscesses. In chronic forms ...
DailyMed - ITRACONAZOLE capsule
Treatment of Blastomycosis and Histoplasmosis. The recommended dose is 200 mg once daily (2 capsules). If there is no obvious ... Blastomycosis. Analyses were conducted on data from two open-label, non-concurrently controlled studies (N=73 combined) in ... Blastomycosis, pulmonary and extrapulmonary. *Histoplasmosis, including chronic cavitary pulmonary disease and disseminated, ... of these two studies demonstrated substantial evidence of the effectiveness of itraconazole for the treatment of blastomycosis ...
North American blastomycosis in Africans. - Libyan Medical Library
First Japanese case of disseminated blastomycosis imported from North America: A case report. | J Infect Chemother;29(10): 988...
Although antibody tests could not diagnose the disease, blastomycosis was suspected based on the pathology of the skin and lung ... Blastomycosis is a fungal infectious disease that can occur in both immunocompromised and immunocompetent populations endemic ... First Japanese case of disseminated blastomycosis imported from North America: A case report.. Ogura, Yuri; Yaguchi, Takashi; ... We reported the first Japanese case of blastomycosis with pulmonary and cutaneous involvement in Japan. As the number of ...
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6. Severe blastomycosis in infants.. Pelly L; Al Juaid A; Fanella S. Pediatr Infect Dis J; 2014 Nov; 33(11):1189-91. PubMed ID ... Treatment of blastomycosis with itraconazole in 112 dogs.. Legendre AM; Rohrbach BW; Toal RL; Rinaldi MG; Grace LL; Jones JB. J ... 2. Therapy of blastomycosis.. Bradsher RW. Semin Respir Infect; 1997 Sep; 12(3):263-7. PubMed ID: 9313298. [TBL] ... Blastomycosis.. Bradsher RW. Clin Infect Dis; 1992 Mar; 14 Suppl 1():S82-90. PubMed ID: 1314106. [TBL] ...
HistoplasmosisEndemic mycosesBlastomycesAspergillosisAmphotericinDiagnosisSymptomsClinicalDeathsFungusPatientsCommonlyArticleDiseaseCaseDeathPeopleLast weekCultureMedicineHistoplasmosisPulmonary blastomycosisGilchristLaryngealDiagnosesExtrapulmonaryLungs1990ClinicallyClinicalSystemicSporesLungChronicPneumoniaEndemicityMildPatientSuspicionCasesCentral nervouSkinTreatmentRegions
Histoplasmosis11
- The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that are frequently misdiagnosed. (cdc.gov)
- Participants will also be introduced to new clinical diagnostic algorithms to address these challenges and improve the timely diagnosis of blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of delayed and underdiagnosed cases. (cdc.gov)
- Discuss diagnostic challenges associated with blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Identify populations clinicians should consider testing for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Describe diagnostic tests clinicians should consider initially and after a negative test for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Discuss the implementation of the clinical diagnostic algorithms for blastomycosis, coccidiomycosis, and histoplasmosis. (cdc.gov)
- Estimates for the annual incidence of HIV-related life-threatening fungal disease include cryptococcal meningitis (8 357 cases), Pneumocystis pneumonia (4 452 cases) and endemic mycoses (emergomycosis, histoplasmosis and blastomycosis, with 100, 60 and 10 cases per year, respectively). (who.int)
- PURPOSE The National Heart, Lung, and Blood Institute (NHLBI) invites research grant applications for support of research on the cellular and molecular mechanisms that influence host susceptibility to HIV-associated lung diseases, including tuberculosis, histoplasmosis, coccidioidomycosis, blastomycosis, Pneumocystis carinii pneumonia, and pulmonary Kaposi's sarcoma. (nih.gov)
- Ketoconazole is a prescription medication used to treat fungal infections, including the following: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis for patients in which other treatments have failed or who are intolerant to other therapies. (rxwiki.com)
- Ketoconazole tablets are prescription medicine used to treat serious fungal infections including: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. (nih.gov)
Endemic mycoses1
- Among the endemic mycoses, blastomycosis has been least often associated with disorders of immune function, but the data presented herein suggest that blastomycosis may occur more commonly in immunocompromised patients than was previously recognized. (nih.gov)
Blastomyces5
- Blastomycosis is an infection caused by a fungus called Blastomyces . (cdc.gov)
- Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. (medlineplus.gov)
- Blastomycosis is an uncommon infection caused by Blastomyces dermatitidis . (bvsalud.org)
- Diana Khuu] Blastomycosis is a fungal disease caused by blastomyces dermatitidis. (cdc.gov)
- Diana Khuu] We decided to do this study because, even though we know quite a bit about the biology and risk factors of infection by Blastomyces dermatitidis , the public health burden of blastomycosis deaths in the United States was unknown. (cdc.gov)
Aspergillosis1
- mycotic (fungal) diseases like aspergillosis, blastomycosis among others. (jcehrlich.com)
Amphotericin2
Diagnosis3
- Almost 30% of the patients in our series died secondary to blastomycosis, with most deaths occurring within 5 weeks following the diagnosis. (nih.gov)
- This case showcases the variety of blastomycosis clinical presentation and the importance of blastomycosis in the differential diagnosis of verrucous and papillomatous mucocutaneous lesions. (bvsalud.org)
- In regions where blastomycosis is endemic, the diagnosis should be considered in patients with pulmonary disease. (cdc.gov)
Symptoms2
- Contact your provider if you have symptoms of blastomycosis. (medlineplus.gov)
- Just looked up blastomycosis and he does not present the symptoms. (askavetquestion.com)
Clinical1
- Clinical and laboratory update on blastomycosis. (cdc.gov)
Deaths2
- After looking at blastomycosis deaths from 1990 to 2010 death certificate data, we found that blastomycosis deaths were more likely in older people, men, and Native Americans, or blacks. (cdc.gov)
- We wanted to look at these risk factors among blastomycosis deaths and see if the risk factors extended to mortality rates. (cdc.gov)
Fungus1
- exposed to areas where the fungus could be found, it might be important to ask your doctor to test for blastomycosis. (cdc.gov)
Patients4
- We have observed a marked increased in the number of immunocompromised patients with blastomycosis over the last 15 years, increasing from about 3% of patients seen between 1956 and 1977 to almost 24% patients seen between 1978 and 1991. (nih.gov)
- Furthermore, almost one third of those patients who died of other causes had evidence of persistent blastomycosis at death. (nih.gov)
- Until more data are available, the newer azoles should be used with caution as primary therapy in immunocompromised patients with blastomycosis, and considered only in patients with limited disease and a stable underlying condition. (nih.gov)
- The clearer resulting identification of risk factors from national data may raise provider and community awareness of blastomycosis to make blastomycosis a diagnostic consideration in patients with lung disease. (cdc.gov)
Commonly1
- You can get blastomycosis by contact with moist soil, most commonly where there is rotting wood and leaves. (medlineplus.gov)
Article1
- Diana Khuu is an author on the article, "Blastomycosis Mortality Rates, United States, 1990 to 2010. (cdc.gov)
Disease2
- Rarely fungal disease (e.g. blastomycosis) and cancer may be found in the joint. (vcahospitals.com)
- Similarly, a fungal disease like blastomycosis could do this. (askavetquestion.com)
Case1
- An Atypical Case of Mucocutaneous Blastomycosis in the Greater Toronto Area. (bvsalud.org)
Death1
- So blastomycosis continues to be a noteworthy cause of preventable death in the United States. (cdc.gov)
People4
- People can get blastomycosis after breathing in the microscopic fungal spores from the air. (cdc.gov)
- Diana, what is important for people to know about blastomycosis mortality rates and blastomycosis in particular? (cdc.gov)
- Anyone can get blastomycosis, even people who are otherwise healthy. (cdc.gov)
- An interesting finding is that even though people of Asian descent are at lower risk of dying from blastomycosis than whites, they died at a much younger age. (cdc.gov)
Last week1
- As we discussed last week, the Billerud Paper Mill has a blastomycosis problem. (foodmanufacturing.com)
Culture1
- Blastomycosis can be diagnosed by culture, direct visualization of the yeast in affected tissue, and/or antigen testing. (nih.gov)
Medicine1
- You may not need to take medicine for a mild blastomycosis infection that stays in the lungs. (medlineplus.gov)
Histoplasmosis7
- Histoplasmosis and blastomycosis. (medscape.com)
- Participants will also be introduced to new clinical diagnostic algorithms to address these challenges and improve the timely diagnosis of blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of delayed and underdiagnosed cases. (cdc.gov)
- Discuss diagnostic challenges associated with blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Identify populations clinicians should consider testing for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Describe diagnostic tests clinicians should consider initially and after a negative test for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
- Discuss the implementation of the clinical diagnostic algorithms for blastomycosis, coccidiomycosis, and histoplasmosis. (cdc.gov)
Pulmonary blastomycosis4
- Delays in diagnosis of pulmonary blastomycosis can be reduced if a higher clinical suspicion exists and there is earlier use of sputum potassium hydroxide (KOH) fungal smear, especially after a course of antibiotics has failed to result in clinical improvement. (medscape.com)
- Pulmonary blastomycosis may resemble lung cancer, and blastomycosis osteomyelitis may resemble bony metastasis. (medscape.com)
- Pulmonary blastomycosis. (nih.gov)
- Chronic pulmonary blastomycosis is often misdiagnosed and treated as tuberculosis in disease-endemic and non-disease-endemic areas. (cdc.gov)
Gilchrist1
- Gilchrist first described blastomycosis in 1894, mistakenly attributing the disease to a protozoan. (medscape.com)
Laryngeal2
Diagnoses1
- A doctor diagnoses blastomycosis by sending a sample of sputum or infected tissue to a laboratory to be examined under a microscope and cultured. (msdmanuals.com)
Extrapulmonary2
- Chronic pneumonia is the dominant clinical manifestation of blastomycosis, although extrapulmonary disease is common, usually involving skin and subcutaneous tissue, bones and joints, the prostate gland, and the central nervous system (CNS). (medscape.com)
- Blastomycosis can be a subclinical illness with subsequent protection against progressive infection afforded by cellular immune mechanisms, but it may present with progressive disease with either pulmonary or extrapulmonary disease or both. (nih.gov)
Lungs3
- You may not need to take medicine for a mild blastomycosis infection that stays in the lungs. (medlineplus.gov)
- Thus, blastomycosis affects primarily the lungs, but the fungi occasionally spread through the bloodstream to other areas of the body, most commonly the skin. (msdmanuals.com)
- Sometimes blastomycosis of the lungs causes no symptoms or causes symptoms that disappear quickly and are not recognized. (msdmanuals.com)
19902
- Diana Khuu is an author on the article, "Blastomycosis Mortality Rates, United States, 1990 to 2010. (cdc.gov)
- After looking at blastomycosis deaths from 1990 to 2010 death certificate data, we found that blastomycosis deaths were more likely in older people, men, and Native Americans, or blacks. (cdc.gov)
Clinically1
- The term North American blastomycosis , a commonly uses synonym, evolved to distinguish this disorder from the clinically similar South American blastomycosis, a disease caused by Paracoccidioides brasiliensis . (medscape.com)
Clinical3
- Clinical and laboratory update on blastomycosis. (medscape.com)
- Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America. (medscape.com)
- Endemic blastomycosis in Mississippi: epidemiological and clinical studies. (medscape.com)
Systemic1
- Chronic blastomycosis should always be treated with systemic antifungal therapy, and oral itraconazole is the drug of choice for mild to moderate forms of the disease. (medscape.com)
Spores1
- People can get blastomycosis after breathing in the microscopic fungal spores from the air. (cdc.gov)
Lung1
- Blastomycosis: fungal infections of the lung update: 1989. (nih.gov)
Chronic1
- Most cases of blastomycosis are usually diagnosed after the infection has become chronic. (cdc.gov)
Pneumonia2
- Establishing blastomycosis as the cause of pneumonia is often difficult, and most patients received multiple antibiotic courses before being diagnosed. (medscape.com)
- In the acute stage, blastomycosis may be misdiagnosed as bacterial pneumonia and sometimes as another illness. (cdc.gov)
Endemicity1
- Notes from the field: Blastomycosis cases occurring outside of regions with known endemicity - New York, 2007-2017. (medscape.com)
Mild1
- Patients with mild to moderate disseminated blastomycosis without central nervous system involvement should be treated for 6 months. (medscape.com)
Patient2
- Composite photomicrograph of a tissue specimen from a patient with blastomycosis infection shows an abundance of large budding cells that had been configured in chains. (medscape.com)
- Patient with blastomycosis, India, 2014. (cdc.gov)
Suspicion1
- Because of strong suspicion of a fungal infection, probably blastomycosis, and considering the patient's stay in Chicago, anti-TB therapy was replaced with itraconazole at a dose of 200 mg 2×/d. (cdc.gov)
Cases1
- It was not until 1951, following the detailed pathologic description of blastomycosis by Schwarz and Baum, [ 9 ] that it was discovered that most cases of the disorder were acquired via the respiratory, not cutaneous, route of inoculation. (medscape.com)
Central nervou1
- Central nervous system blastomycosis may resemble brain neoplasm. (medscape.com)
Skin1
- The typical verrucous or ulcerative cutaneous lesions of blastomycosis may mimic skin cancers, such as basal cell carcinoma and squamous cell carcinoma. (medscape.com)
Treatment1
- Blastomycosis requires prolonged treatment. (medscape.com)
Regions1
- The blastomycosis mortality rates were highest in the Midwestern and Southern regions, and we saw that the mortality rate in the Midwestern region has been increasing over the last two decades. (cdc.gov)
