Dichlorophen
Hexachlorophene
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Fasciola hepatica infestation as a very rare cause of extrahepatic cholestasis. (1/11)
Fasciola hepatica, an endemic parasite in Turkey, is still a very rare cause of cholestasis worldwide. Through ingestion of contaminated water plants like watercress, humans can become the definitive host of this parasite. Cholestatic symptoms may be sudden but in some cases they may be preceded by a long period of fever, eosinophilia and vague gastrointestinal symptoms. We report a woman with cholangitis symptoms of sudden onset which was proved to be due to Fasciola hepatica infestation by an endoscopic retrograde cholangiography. (+info)Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons. (2/11)
The Slack (sequence like a calcium-activated K channel) and Slick (sequence like an intermediate conductance K channel) genes, which encode sodium-activated K+ (K(Na)) channels, are expressed at high levels in neurons of the medial nucleus of the trapezoid body (MNTB) in the auditory brainstem. These neurons lock their action potentials to incoming stimuli with a high degree of temporal precision. Channels with unitary properties similar to those of Slack and/or Slick channels, which are gated by [Na+]i and [Cl-]i and by changes in cytoplasmic ATP levels, are present in MNTB neurons. Manipulations of the level of K(Na) current in MNTB neurons, either by increasing levels of internal Na+ or by exposure to a pharmacological activator of Slack channels, significantly enhance the accuracy of timing of action potentials at high frequencies of stimulation. These findings suggest that such fidelity of timing at high frequencies may be attributed in part to high-conductance K(Na) channels. (+info)Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection. (3/11)
To establish a reliable diagnostic measure for equine Anoplocephala perfoliata infection, the impact of deworming was examined in 12 Thoroughbreds to which bithionol (5-10 mg/kg body weight) was administered and feces were examined by the modified Wisconsin method using sucrose solution. One day after the administration, cestode eggs were detected in previously fecal egg-negative 3 horses and increased in the other 9 horses. The optimum time for post-deworming egg detection was examined in following horses: 17 mares were administered bithionol and 10 mares were used as controls. The fecal egg count was significantly (P<0.01) higher one day after the administration than that on other pre- and post-administration days, while no significant changes occurred in fecal egg count in the controls, demonstrating that one day after bithionol administration is the optimum time for detecting fecal cestode eggs. The diagnostic deworming involving bithionol and fecal examination on the day following administration provides a reliable diagnosis for equine Anoplocephala perfoliata infection. (+info)Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. (4/11)
(+info)Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity. (5/11)
(+info)Involvement of autotaxin/lysophospholipase D expression in intestinal vessels in aggravation of intestinal damage through lymphocyte migration. (6/11)
(+info)Rapid identification of antifungal compounds against Exserohilum rostratum using high throughput drug repurposing screens. (7/11)
(+info)In vitro inhibition of Giardia lamblia and Trichomonas vaginalis growth by bithionol, dichlorophene, and hexachlorophene. (8/11)
Bithionol, dichlorophene, and hexachlorophene, which are used in treating some helminthic infections, killed trophozoites of Giardia lamblia and Trichomonas vaginalis in modified BI-S-33 and Asami media, respectively. Virtually all G. lamblia and T. vaginalis cells were killed within 24 h with a 0.42 mM concentration of these compounds, except that 0.93 mM dichlorophene was required for sterilizing T. vaginalis in the same period. In modified BI-S-33 and Asami media from which bovine and human sera were omitted, respectively, the inhibitory actions of the compounds against in vitro growth of these protozoa were significantly enhanced. Trophozoites of G. lamblia and T. vaginalis could be killed in shorter than 10 min with 0.074 mM dichlorophene and 0.0025 mM hexachlorophene, respectively, in serum-free media. G. lamblia, which was incubated in the complete medium containing dichlorophene, showed a characteristic swelling of the ventral side which led to disruption of the parasite, whereas bithionol caused a thin crack in the cytoplasm of T. vaginalis incubated in Asami medium. The crack appeared to enlarge and result in vacuolization of T. vaginalis. These observations suggest that bithionol, dichlorophene, and hexachlorophene merit further evaluation to ascertain whether they are useful for treatment of giardiasis and trichomoniasis. (+info)
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Bithionol for human therapeutic use. Bragantia spp. containing aristolochic acid(s) for human therapeutic use. Buclosamide for ...
Fasciolosis
Praziquantel is not effective, and older drugs such as bithionol are moderately effective but also cause more side effects. ... There are also reports of bithionol being used successfully. Nitazoxanide has been found effective in trials, but is currently ... Fasciolicides (drugs against Fasciola spp.) fall into five main chemical groups: Halogenated phenols: bithionol (Bitin), ...
Clonorchis sinensis
Drugs used to treat infestation include triclabendazole, praziquantel, bithionol, albendazole, levamisole, and mebendazole. ...
Paragonimiasis
The drug of choice to treat paragonimiasis is praziquantel, although bithionol may also be used. Triclabendazole is useful in P ...
Fasciola hepatica
... and bithionol. Ivermectin, which is widely used for many helminthic parasites, has low effectivity against F. hepatica, as does ...
Paragonimus
Other medications can also be used such as bithionol, niclofan, and triclabendazole with high cure rates. Thorough cooking of ...
Moniliformis moniliformis
To obtain the worms from the host, piperazine citrate, levamisole and bithionol can be administered to the patient. ...
Paragonimus westermani
Bithionol is an alternative drug for treatment of this disease but is associated with skin rashes and urticaria. For additional ...
Microcotyle sebastis
100 mg bithionol/kg B.W. or 200 mg bithionol/kg B.W. significantly reduces the numbers of this monogenean on the gills of the ... Ki Hong Kim & Eun Seok Choi evaluated the oral administration of mebendazole or bithionol for the control of Microcotyle ... with oral administration of mebendazole and bithionol". Aquaculture. 167 (1-2): 115-121. doi:10.1016/S0044-8486(98)00300-7. ...
Metagonimiasis
... including bithionol, niclosamide, nicoflan, and Praziquantel. All drugs showed lower prevalence of eggs in feces, however only ...
Nanophyetus
Three 2-g doses of niclosamide or two 50 mg/kg doses of bithionol have also been effective when praziquantel was either not ...
Paragonimus skrjabini
... unlike the previously used drug bithionol, which required extended treatment and involved more severe side effects. The latest ...
Gnathostoma spinigerum
On the other hand, there are other antihelminthic drugs available such as bithionol, thiabendazole, metronidazole, and others, ...
Philasterides dicentrarchi
Several compounds of well-known antiprotozoal activity, including niclosamide, oxyclozanide, bithionol sulfoxide, toltrazuril, ...
ATC code D10
D10AA01 Fluorometholone D10AA02 Methylprednisolone D10AA03 Dexamethasone D10AB01 Bithionol D10AB02 Sulfur D10AB03 Tioxolone ...
List of drugs: Bi-Bo
... bithionol (INN) bithionoloxide (INN) bitipazone (INN) bitolterol (INN) bitoscanate (INN) bivalirudin (INN) bivatuzumab ...
Sodium salts
Examples of such sodium salts are (selection): Bispyribac, bithionol, bosentan, brequinar, bromfenac, Cefmenoxime, ceftiofur, ...
Amoebic gill disease
... mucolytic compounds such as L-cysteine ethyl ester and the parasiticide bithionol have been tested with some success although ...
C12H6Cl4O2S
The molecular formula C12H6Cl4O2S (molar mass: 356.052 g/mol, exact mass: 353.8843 u) may refer to: Bithionol Tetradifon This ...
List of fungicides
... fungicides benzohydroxamic acid benzothiazole fungicides bethoxazin binapacryl biphenyl bitertanol bithionol bixafen ...
ATCvet code QP52
QP52AG02 Hexachlorophene QP52AG03 Niclosamide QP52AG04 Resorantel QP52AG05 Rafoxanide QP52AG06 Oxyclozanide QP52AG07 Bithionol ...
ATC code P02
P02BA01 Praziquantel P02BA02 Oxamniquine P02BB01 Metrifonate P02BX01 Bithionol P02BX02 Niridazole P02BX03 Stibophen P02BX04 ...
Bithionol
... was formerly used in soaps and cosmetics until the U.S. FDA banned it for its photosensitizing effects. The compound ... Bithionol has two aromatic rings with a sulfur atom bonded between them and multiple chlorine ions and hydroxyl groups attached ... Bithionol is the first known soluble adenylyl cyclase inhibitor to act through the bicarbonate binding site via a mostly ... Bithionol is an antibacterial, anthelmintic, and algaecide. It is used to treat Anoplocephala perfoliata (tapeworms) in horses ...
Suramin
The most frequent adverse reactions are nausea, vomiting, diarrhea, abdominal pain, and a feeling of general discomfort. It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet.[10] Other skin reactions include skin rash, swelling and stinging sensation.[10] Suramin can also cause loss of appetite and irritability.[10] Suramin causes non-harmful changes in urine during use, specifically making the urine cloudy.[10] It may exacerbate kidney disease.[11] Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin.[10] Suramin uncommonly affects the eyes causing watery eyes, swelling around the eyes, photophobia, and changes or loss of vision.[10] Rare side effects include hypersensitivity reactions causing difficulty breathing. Other rare systemic effects include decreased blood pressure, fever, rapid heart ...
Bithionol - Wikipedia
Bithionol was formerly used in soaps and cosmetics until the U.S. FDA banned it for its photosensitizing effects. The compound ... Bithionol has two aromatic rings with a sulfur atom bonded between them and multiple chlorine ions and hydroxyl groups attached ... Bithionol is the first known soluble adenylyl cyclase inhibitor to act through the bicarbonate binding site via a mostly ... Bithionol is an antibacterial, anthelmintic, and algaecide. It is used to treat Anoplocephala perfoliata (tapeworms) in horses ...
Bithionol | C12H6Cl4O2S - PubChem
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These prohibited substances include bithionol, chloroform, mercury compounds, methylene chloride, vinyl chloride, and ... These prohibited substances include bithionol, chloroform, mercury compounds, methylene chloride, vinyl chloride, and ... These prohibited substances include bithionol, chloroform, mercury compounds, methylene chloride, vinyl chloride, and ...
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The study found that bithionol, a drug that used to treat parasitic infections in horses, could be used to treat antibiotic- ... When used in high doses, bithionol causes the cells of bacteria to burst open and die-but this might cause bacteria to become ... Researchers found that using lower doses of bithionol to weaken bacteria, and then a traditional antibiotic to finish the job, ... Of course, the danger of bacteria eventually becoming resistant to bithionol, too, is ever present. But not to worry! ...
Code System Concept
ICB-1000 | International Comprehensive Baseline Series International Standard Series - innosoulmed.com
The series can be seen as an important addition for those physicians who either do not have a domestic baseline series or want to go beyond the various baseline series offered. The experience has been that a larger routine screening series will produce a higher yield of positive reactions and contribute to a better diagnosis.. ...
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Suramin - Wikipedia
The most frequent adverse reactions are nausea, vomiting, diarrhea, abdominal pain, and a feeling of general discomfort. It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet.[10] Other skin reactions include skin rash, swelling and stinging sensation.[10] Suramin can also cause loss of appetite and irritability.[10] Suramin causes non-harmful changes in urine during use, specifically making the urine cloudy.[10] It may exacerbate kidney disease.[11] Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin.[10] Suramin uncommonly affects the eyes causing watery eyes, swelling around the eyes, photophobia, and changes or loss of vision.[10] Rare side effects include hypersensitivity reactions causing difficulty breathing. Other rare systemic effects include decreased blood pressure, fever, rapid heart ...
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Hydroxychloroquine toxicity treatment
The dosage and length of treatment are based on your medical condition and response to therapy. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis 1 day ago · Hydroxychloroquine and chloroquine inhibit SARS-CoV-2 in vitro, and a Chinese commentary, mentioning 15 trials, reported that, "Thus far, results from more than 100 patients have demonstrated that chloroquine phosphate is superior to the control treatment in inhibiting the exacerbation of pneumonia,"19 without giving any further details Hydroxychloroquine (HCQ), sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Initially, chloroquine was given for malaria prophylaxis and treatment Mar 19, 2020 · What Is It: Hydroxycholorquine (sold under the brand name Plaquenil), and the closely related chloroquine, were approved in the 1950s mainly as anti-malaria treatments Jan 07, 2020 · Daily ...
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- Bithionol has two aromatic rings with a sulfur atom bonded between them and multiple chlorine ions and hydroxyl groups attached to the phenyl groups. (wikipedia.org)
- The side chain of arginine 176 within the bicarbonate binding site interacts significantly with the aromatic ring of the bithionol molecule. (wikipedia.org)
Sodium1
- In another form of inhibition, bithionol is a much larger molecule than simple sodium bicarbonate, so it is large enough to reach through a small channel in the soluble adenylyl cyclase and interfere with binding of ATP, preventing its conversion to cAMP. (wikipedia.org)
Lower2
- This inhibition of the soluble adenylyl cyclase by bithionol at the bicarbonate binding site is demonstrated through a mixed-inhibition graph, where higher concentrations of bithionol have a lower Vmax and a larger Km. (wikipedia.org)
- Researchers found that using lower doses of bithionol to weaken bacteria, and then a traditional antibiotic to finish the job, was more effective. (anh-usa.org)
Traditional1
- The problem is that the traditional medications, like bithionol, have many side-effects, are nasonex good price pharmacy very expensive, and many of them show no results. (sexsmithselfstorage.com)
Drug3
- The study found that bithionol, a drug that used to treat parasitic infections in horses, could be used to treat antibiotic-resistant bacteria like MRSA , which infects 90,000 Americans each year and kills 20,000. (anh-usa.org)
- One promising drug is bithionol. (oncoloradosprings.com)
- Bithionol is an anti-parasitic drug and can be used to inhibit solid tumor growth in several preclinical cancer models. (csnpharm.cn)
Year1
- This graph shows the total number of publications written about "Bithionol" by people in this website by year, and whether "Bithionol" was a major or minor topic of these publications. (ucdenver.edu)
Treat1
- Previously used to treat parasitic infections in horses, bithionol is now being. (oncoloradosprings.com)
Nitazoxanide2
- The Global Liver Fluke Treatment Market has been segmented by Drug Type into Triclabendazole, Praziquantel, Bithionol, Nitazoxanide and Albendazole. (reanin.com)
- praziquantel albendazole triclabendazole, bithionol,nitazoxanide substitue with ivermectin Moreover, if they are lying about their digital footprint, you must avoid them. (draxray.com)
Ingredients1
- by Farmers Elevator Service Co., Inc. LABEL IN PART: (Bag) "Felco Feed Premix medicated for the prevention of Coccidiosis in Chickens * * * Active drug ingredients: Bithionol 10.0 per- cent Methitriazamine 2.0 percent * * * Manufactured for Farmers Elevator Service Company * * * Fort Dodge, Iowa. (nih.gov)
Previously2
- Bithionol, a halogenated phenol previously used as first line agent for the treatment of fascioliasis in USA is no longer available. (medscape.com)
- Previously used to treat parasitic infections in horses, bithionol is now being used to treat MRSA (Methicillin-resistant Staphylococcus aureus) and other antibiotic resistant bacterial infections. (oncoloradosprings.com)
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