Birnaviridae: A family of bisegmented, double-stranded RNA viruses causing infection in fish, mollusks, fowl, and Drosophila. There are three genera: AQUABIRNAVIRUS; AVIBIRNAVIRUS; and ENTOMOBIRNAVIRUS. Horizontal and vertical transmission occurs for all viruses.Birnaviridae Infections: Virus diseases caused by the BIRNAVIRIDAE.Aquabirnavirus: A genus of RNA viruses in the family BIRNAVIRIDAE infecting fish, mollusks, and crustaceans. It is transmitted both vertically and horizontally with no known vectors. The natural hosts are salmonids and the type species is INFECTIOUS PANCREATIC NECROSIS VIRUS.Infectious bursal disease virus: A species of AVIBIRNAVIRUS causing severe inflammation of the bursa of Fabricius in chickens and other fowl. Transmission is thought to be through contaminated feed or water. Vaccines have been used with varying degrees of success.Infectious pancreatic necrosis virus: The type species of AQUABIRNAVIRUS, causing infectious pancreatic necrosis in salmonid fish and other freshwater and marine animals including mollusks.Viral Structural Proteins: Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.RNA Replicase: An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)DelawareBursa of Fabricius: An epithelial outgrowth of the cloaca in birds similar to the thymus in mammals. It atrophies within 6 months after birth and remains as a fibrous remnant in adult birds. It is composed of lymphoid tissue and prior to involution, is the site of B-lymphocyte maturation.Avibirnavirus: A genus of RNA viruses in the family BIRNAVIRIDAE infecting birds. It is transmitted horizontally with no known vectors. The type species is INFECTIOUS BURSAL DISEASE VIRUS.Poultry Diseases: Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.Cryoelectron Microscopy: Electron microscopy involving rapid freezing of the samples. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.Capsid: The outer protein protective shell of a virus, which protects the viral nucleic acid.Rickettsiaceae: A family of small, gram-negative organisms, often parasitic in humans and other animals, causing diseases that may be transmitted by invertebrate vectors.Capsid Proteins: Proteins that form the CAPSID of VIRUSES.Virus Assembly: The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.Virion: The infective system of a virus, composed of the viral genome, a protein core, and a protein coat called a capsid, which may be naked or enclosed in a lipoprotein envelope called the peplos.Face: The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Fish Diseases: Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates).Salmon: Fish of the genera ONCORHYNCHUS and Salmo in the family SALMONIDAE. They are anadromous game fish, frequenting the coastal waters of both the North Atlantic and Pacific. They are known for their gameness as a sport fish and for the quality of their flesh as a table fish. (Webster, 3d ed).Salmonidae: A family of anadromous fish comprising SALMON; TROUT; whitefish; and graylings. They are the most important food and game fishes. Their habitat is the northern Atlantic and Pacific, both marine and inland, and the Great Lakes. (Nelson: Fishes of the World, 1976, p97)Chickens: Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.Reoviridae Infections: Infections produced by reoviruses, general or unspecified.Wolfram Syndrome: A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.Eucommiaceae: A plant family of the order Eucommiales, subclass Hamamelidae, class Magnoliopsida (some botanists have classified this in the order Hamamelidales or Urticales). Eucomia is an elmlike tree of central and eastern China. Leaves are alternate; deciduous flowers are solitary and unisexual and lack petals and sepals. The male flowers have 6 to 10 stamens and female flowers have one ovary of two carpels, one of which aborts during development so the fruit (a dry, winged structure) contains only one seed. The latex is a source of RUBBER. Tochu tea is an aqueous extract of Eucommia ulmoides leaves and a popular beverage in Japan. (Mutat Res 1997 Jan 15;388(1):7-20).Literature, ModernChristianity: The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)Diptera: An order of the class Insecta. Wings, when present, number two and distinguish Diptera from other so-called flies, while the halteres, or reduced hindwings, separate Diptera from other insects with one pair of wings. The order includes the families Calliphoridae, Oestridae, Phoridae, SARCOPHAGIDAE, Scatophagidae, Sciaridae, SIMULIIDAE, Tabanidae, Therevidae, Trypetidae, CERATOPOGONIDAE; CHIRONOMIDAE; CULICIDAE; DROSOPHILIDAE; GLOSSINIDAE; MUSCIDAE; TEPHRITIDAE; and PSYCHODIDAE. The larval form of Diptera species are called maggots (see LARVA).Tankyrases: A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and have poly(ADP-ribose) polymerase activity.Bromeliaceae: A plant family of the order Bromeliales, subclass Zingiberidae, class Liliopsida (monocotyledons).Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Inventions: A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.Nimustine: Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.Amination: The creation of an amine. It can be produced by the addition of an amino group to an organic compound or reduction of a nitro group.ThiophenesFurans: Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.Peptide Library: A collection of cloned peptides, or chemically synthesized peptides, frequently consisting of all possible combinations of amino acids making up an n-amino acid peptide.Single-Chain Antibodies: A form of antibodies consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.Plum Pox Virus: A species of the genus POTYVIRUS that affects many species of Prunus. It is transmitted by aphids and by infected rootstocks.Hemagglutination Tests: Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (From Stedman, 26th ed)Fowlpox: A poxvirus infection of poultry and other birds characterized by the formation of wart-like nodules on the skin and diphtheritic necrotic masses (cankers) in the upper digestive and respiratory tracts.Silicates: The generic term for salts derived from silica or the silicic acids. They contain silicon, oxygen, and one or more metals, and may contain hydrogen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th Ed)Fowlpox virus: The type species of the genus AVIPOXVIRUS. It is the etiologic agent of FOWLPOX.Reticuloendotheliosis, Avian: A group of pathologic syndromes found in avian species caused by RETICULOENDOTHELIOSIS VIRUS. The distinct syndromes include non-neoplastic runting, acute neoplastic disease, and chronic neoplastic disease. Humans and mammals appear resistant.Prunus: A plant genus in the family ROSACEAE, order Rosales, subclass Rosidae. It is best known as a source of edible fruits such as apricot, plum, peach, cherry, and almond.Ficus: A plant genus of the family MORACEAE. It is the source of the familiar fig fruit and the latex from this tree contains FICAIN.Commelina: A plant genus of the family COMMELINACEAE of perennial herbs with blue flowers.Plants, Medicinal: Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Anti-Infective Agents: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.

Adaptation of very virulent infectious bursal disease virus to chicken embryonic fibroblasts by site-directed mutagenesis of residues 279 and 284 of viral coat protein VP2. (1/120)

The full-length RNA genomes of a chicken embryonic fibroblast (CEF)-nonpermissive, very virulent infectious bursal disease virus (IBDV) (strain HK46) were amplified into cDNAs by reverse transcription-PCR. The full-length cDNAs were sequenced and subcloned into a eukaryotic expression vector, from which point mutations were introduced into the VP2 region by site-directed mutagenesis. The wild-type and mutated plasmids were transfected directly into CEFs to examine their ability to generate CEF-permissive recombinant viruses. Substitution of amino acid residues 279 (Asp-->Asn) and 284 (Ala-->Thr) of the VP2 protein yielded a recombinant virus which was able to be passaged in CEFs, whereas the wild-type cDNAs and an amino acid substitution at residue 330 (Ser-->Arg) of the VP2 protein alone did not yield viable virus. The results indicated that mutation of other viral proteins, including VP1, VP3, VP4, and VP5, was not required for CEF adaptation of the virus. The same approach may be used to produce CEF-adapted strains from newly evolved IBDVs or to manipulate the antigenicity of the virus.  (+info)

Lysis of myelocytes in chickens infected with infectious bursal disease virus. (2/120)

In specific-pathogen-free chickens infected with the highly virulent HPS-2 strain or virulent reference GBF-1 strain of infectious bursal disease virus (IBDV), pathologic changes of the bone marrow were investigated. On histologic examination, bone marrow lesions were prominent in the HPS-2 group but only mild in the GBF-1 group. The bone marrow of the HPS-2 group showed severe lysis and depletion of heterophil myelocytes with pyknotic nuclear alteration 2-3 days after inoculation. On examination with an electron microscope, heterophil myelocytes were characterized by shrinkage of the cytoplasm and peripheral condensation of nuclear chromatin. IBDV particles were not detected in altered myelocytes. A terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling method demonstrated a positive reaction in only heterophil myelocytes. In contrast, nucleosomal DNA fragmentation in HPS-2-infected bone marrow cells was indiscernible by agarose gel electrophoresis. These findings indicate that lysis of bone marrow cells is selectively induced in heterophil myelocytes at an early stage after IBDV infection and independent of virus replication.  (+info)

Protection of chickens against very virulent infectious bursal disease virus (IBDV) and Marek's disease virus (MDV) with a recombinant MDV expressing IBDV VP2. (3/120)

To develop a herpes virus vaccine that can induce immunity for an extended period, a recombinant Marek's disease (MD) virus (MDV) CVI-988 strain expressing infectious bursal disease virus (IBDV) host-protective antigen VP2 at the US2 site (rMDV) was developed under the control of an SV40 early promoter. Chickens vaccinated with the rMDV showed no clinical signs and no mortality and 55% of the chickens were considered protected histopathologically after challenge with very virulent IBDV (vvIBDV), whereas all of the chickens vaccinated with the conventional IBDV vaccine showed no clinical signs and were protected. Chickens vaccinated with the CVI-988 or chickens in the challenge control showed severe clinical signs and high mortality (70-75%) and none of them were protected. Also, the rMDV conferred full protection to chickens against vvMDV just as the CVI-988 strain did, whereas 90% of the challenge control chickens died of MD. Antibody levels against IBDV and MDV following the vaccination increased continuously for at least 10 weeks. No histopathological lesions in the rMDV-vaccinated chickens and no contact transmission of the rMDV to their penmates were confirmed. These results demonstrate that an effective and safe recombinant herpesvirus-based IBD vaccine could be constructed by expressing the VP2 antigen at the US2 site of the CVI-988 vaccine strain.  (+info)

Sequence comparison of the VP2 variable region of infectious bursal disease virus isolates from Vietnam. (4/120)

The variable region in the VP2 gene of twenty-three infectious bursal disease virus (IBDV) isolates, collected in Vietnam in 1997 and 1998, was amplified as cDNA by using the reverse transcription-polymerase chain reaction and sequenced. Analysis of amino acid substitutions and phylogenetic relationships of the deduced amino acid sequences (residues 206-350) showed that the nineteen Vietnamese vv IBDVs clustered with the European vv IBDVs, Japanese vv IBDVs and Chinese vv strains, and that the four vietnamese virulent strains were closely related to European virulent strain 52/70. These results suggest that Vietnamese vv IBDVs, European vv IBDVs, Japanese vv IBDVs and Chinese vv strains have the same origin.  (+info)

Gill lamellar pillar cell necrosis, a new birnavirus disease in Japanese eels. (5/120)

Since the late 1980s, a birnaviral gill disease has been occurring in Japanese eels Anguilla japonica reared in warmwater ponds in western regions in Japan. Diseased eels mostly displayed marked formations of aneurysmal hematomas within gill lamellae and high mortalities. Histological examination revealed necrosis of pillar cells and subsequent aggregation of erythrocytes inside the lamellar capillaries, and proliferation of interlamellar epithelia onto the lamellae. Gastric gland cells were also necrotized. Electron microscopy revealed birnavirus infection in lamellar pillar cells. The causative birnavirus was isolated and cultured in fish cell lines and was found to be related to an infectious pancreatic necrosis virus (IPNV) Sp serotype by neutralization tests. The viral pathogenicity was confirmed by the results of histopathological examinations and infectivity experiments.  (+info)

Effect of thymus extract on immunologic reactivity of chicken vaccinated with infectious bursal disease virus. (6/120)

The effects of crude thymus extract on the immune response and protection against challenge with virulent infectious bursal disease virus (IBDV) were studied in one-day-old chick. Oral administration of thymus extract (1 ml/kg) markedly and significantly increased the total protein, albumin, globulin, Tri-iodothyronine (T3), Thyroxine (T4) and the body weight gain in one-day-old chick. In addition, it increased the total lymphocytic count over four weeks after administration. Although vaccination also increased total protein, globulin, T4 and the total lymphocytic count but it significantly decreased the body weight gain of the chick and administration of thymus extract, before, during or after vaccination markedly improved the vaccination effectiveness with significant elevation of the globulin level and body weight gain of the chick. It also prevented the decrease in the relative weights of bursa, spleen and thyroid gland which commonly prevailed during vaccination. Chicken administered thymus extract and vaccinated with infectious bursal disease (IBD) vaccine showed 100% protection against challenge with IBDV. Meanwhile the vaccinated non-thymus treated group exhibited 80% protection against IBDV challenge. These results indicate a potentiating effect of thymus extract on the immune system in baby chick. These findings are supported by ELISA results that showed a marked increase in antibody titers in thymus treated groups. Additionally, microscopical examination of the bursa and the existent lymphoid hyperplasia in thymus treated groups but not vaccinated group support our findings.  (+info)

Inter-laboratory comparison of cell lines for susceptibility to three viruses: VHSV, IHNV and IPNV. (7/120)

Eleven European National Reference Laboratories participated in an inter-laboratory comparison of the susceptibility of 5 selected cell lines to 3 fish pathogenic viruses. The test included viral hemorrhagic septicaemia virus (VHSV); infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV), and the cell lines derived from bluegill fry (BF-2), chinook salmon embryo (CHSE-214), epithelioma papulosum cyprini (EPC), fathead minnow (FHM) and rainbow trout gonad (RTG-2). The results showed that for isolation of VHSV, BF-2 and RTG-2 cells performed equally well and had higher sensitivity compared to the other cell lines. For IHNV, EPC and FHM cells gave the best results, and for IPNV it was BF-2 and CHSE-214 cells. FHM cells showed the largest variability among laboratories, whereas EPC was the cell line showing the smallest variability.  (+info)

Multiplex reverse transcriptase PCR assay for simultaneous detection of three fish viruses. (8/120)

A multiplex reverse transcriptase (RT)-PCR assay was developed for the simultaneous detection of three different fish viruses: infectious pancreatic necrosis virus (IPNV), infectious hematopoietic necrosis virus (IHNV), and viral hemorrhagic septicemia virus (VHSV). The sensitivity levels of the multiplex RT-PCR assay were 100, 1, and 32 50% tissue culture infective doses/ml for IPNV, IHNV, and VHSV, respectively.  (+info)

TY - JOUR. T1 - Modulation of macrophages by infectious bursal disease virus. AU - Khatri, M.. AU - Sharma, J. M.. PY - 2007/7/1. Y1 - 2007/7/1. N2 - Infectious bursal disease is one of the most important naturally occurring viral diseases of chickens worldwide. The causative agent, infectious bursal disease virus (IBDV), belongs to the family Birnaviridae. This viruscauses an acute, highly contagious and immunosuppressive disease in chickens. The virus infects and destroys actively dividing IgM-bearing B cells. Although B cells are the principal targets for IBDV, recent data show that the virus also infects macrophages. IBDV-infected macrophages produce various cytokines and chemokines which may play an important role in the protection and/or pathogenesis of IBDV. In this review, the modulatory effects of IBDV on macrophages will be discussed.. AB - Infectious bursal disease is one of the most important naturally occurring viral diseases of chickens worldwide. The causative agent, infectious ...
詹明才。1992。農桿菌轉殖水稻系統的建立。國立台灣大學農藝學研究所博士論文。 Alvarez, M.L., Pinyerd, H.L., Topal, E. and Cardineau, G.A. 2008. P19-dependent and P19-independent reversion of F1-V gene silencing in tomato.Plant Molecular Biology 68:61-79. Angel, C.A., Hsieh, Y.C., Schoelz, J.E. 2011. Comparative analysis of the capacity of tombusvirus P22 and P19 proteins to function as avirulence determinants in Nicotiana species. Molecular Plant-Microbe Interactions 24:91-99. Arnold, M., Durairaj, V., Mundt, E., Schulze, K., Breunig, K.D., Behrens, S.E.2012. Protective vaccination against infectious bursal disease virus with whole recombinant Kluyveromyces lactis yeast expressing the viral VP2 subunit. PLoS ONE 7:e42870. Azad, A. A. Mckern, N. M., Macreadie, I. G., Failla, P., Heine, H. G., Chapman, A., Ward, C. W., Fahey, K. J. 1991. Physicochemical and immunological characterization of recombinant host-protective antigen (VP2) of infectious bursal disease ...
Read "Infectivity and propagation of attenuated infectious bursal disease virus in the chicken B-lymphocyte cell line DT40, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Testing by the egg and poultry industries, Biosecurity New Zealand and a specialist overseas laboratory confirmed the presence of the chicken virus infectious bursal disease virus type 1 (IBDV-1) in layer hens at a South Island egg farm in September 2019.. The likely presence of the disease was first picked up by Mainland Poultry at its Waikouaiti farm in Otago through its regular, voluntary testing routine. No birds at the farm have shown any signs of sickness due to IBDV-1 infection. Results of testing from Mainland Poultrys Hillgrove site returned positive at this location. No other properties appear to be affected.. IBDV-1 was previously discovered in New Zealand in 1993. An industry-led programme has allowed New Zealand to claim absence from the disease. The virus is present in many other countries and they successfully manage it. ...
The study aimed to identify putative virulence determinants for the exotic poultry pathogen infectious bursal disease virus. Results suggest that three specific amino acids in viral protein 2 influence viral pathogenicity, and as a consequence these were exploited for the development of two new molecular diagnostic assays that are currently undergoing evaluation ...
Read "Efficient rescue of infectious bursal disease virus using a simplified RNA polymerase II-based reverse genetics strategy, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Infectious Bursal Disease Virus (IBDV) alters host genomic methylation patterns. Here the implications for viral release and immunosuppression
REAL, right upper lobe, apical segment (B1), posterior segment (B2), anterior segment (B3), right middle lobe (or more correctly - just middle lobe), lateral segment (B4), medial segment (B5), right lower lobe superior segment (B6), medial segment (B7), anterior segment (B8), lateral segment (B9), posterior segment , left upper lobe, apicoposterior segment (B1/2), anterior segment (B3), superior lingular segment (B4), inferior lingular segment (B5), left lower lobe, superior segment (B6), anteromedial segment (B8), lateral segment (B9), posterior segment (B10), 3d, model, .stl, printable ...
Infectious bursal disease, IBD (also known as Gumboro disease, infectious bursitis and infectious avian nephrosis) is a highly contagious disease of young chickens caused by infectious bursal disease virus (IBDV), characterized by immunosuppression and mortality generally at 3 to 6 weeks of age. The disease was first discovered in Gumboro, Delaware in 1962. It is economically important to the poultry industry worldwide due to increased susceptibility to other diseases and negative interference with effective vaccination. In recent years, very virulent strains of IBDV (vvIBDV), causing severe mortality in chicken, have emerged in Europe, Latin America, South-East Asia, Africa and the Middle East. Infection is via the oro-fecal route, with affected bird excreting high levels of the virus for approximately 2 weeks after infection. IBDV is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus Avibirnavirus of family Birnaviridae. There are two distinct serotypes of the ...
PROPAGATION OF INFECTIOUS PANCREATIC NECROSIS VIRUS IN FISH CELL CULTURES. M. Maistrenko1, Yu. Rud2, L. Buchatsky1,2. This email address is being protected from spambots. You need JavaScript enabled to view it.. 1Taras Shevchenko Kyiv National University, 60, Volodymyrska str., 01033, Kyiv, Ukraine. 2Institute of Fisheries of NAAS, 135, Obukhivska str., 03164, Kyiv, Ukraine. The reproduction of the Ukrainian isolate of infectious pancreatic necrosis virus (IPNV) «Carpathians» in fish continuous cell cultures of RTG-2, FHM and EPC was investigated. All three cell lines were sensitive to virus. IPNV caused morphological changes, such as vacuole enlargements and cells rounding. Subsequently cells scaled from a surface and characteristic cytopathic effect (CPE) of virus on cells was visible. For cell lines of RTG-2 and FHM the complete destruction of monolayer was noted on 7-8 day after infection (d.a.i.). For culture of EPC characteristic CPE and complete destruction of cell monolayer were marked ...
TY - JOUR. T1 - Antigenicity of infectious pancreatic necrosis virus VP2 subviral particles expressed in yeast. AU - Allnutt, F. C.Thomas. AU - Bowers, Robert M.. AU - Rowe, Christopher G.. AU - Vakharia, Vikram N.. AU - LaPatra, Scott E.. AU - Dhar, Arun K.. PY - 2007/6/21. Y1 - 2007/6/21. N2 - Infectious pancreatic necrosis (IPN) virus, the etiologic agent of infectious pancreatic necrosis in salmonid fish, causes significant losses to the aquaculture industry. The gene for the viral capsid protein (VP2) was cloned into a yeast expression vector and expressed in Saccharomyces cerevisae. Expression of the capsid gene in yeast resulted in formation of ∼20 nm subviral particles composed solely of VP2 protein. Anti-IPNV antibodies were detected in rainbow trout vaccinated either by injection of purified VP2-subviral particles (rVP2-SVP) or by feeding recombinant yeast expressing rVP2-SVP. Challenge of rVP2-SVP immunized trout with a heterologous IPNV strain and subsequent viral load ...
Yousif AA, Mohammad WA, Khodeir MH, Zeid AZ, el-Sanousi AA, Saber MS, Reda IM. 2006, Egypt J Immunol. 13(2):85-94.Department of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.Infectious bursal disease (IBD) is one of the most
Two serotypes have been identified in infectious bursal disease virus (IBDV), a member of the family Birnaviridae. A reverse genetics system was used for generation of chimeras in genome segment A of the two serotypes, in which the complete viral VP5 gene and 3′ noncoding region (NCR), or parts thereof, were exchanged. The engineered viruses were characterized in vitro and in vivo in comparison to serotype I and II IBDV. Our results show that IBDV chimeras exhibit a different phenotype in cell culture compared to the wild-type viruses. In in vitro-cultivated bursal-derived cells, chimeric viruses infected B lymphocytes, as does serotype I IBDV. Surprisingly, serotype II virus was also able to infect in vitro-cultivated bursal cells, but these were neither B lymphocytes nor macrophages. After infection of susceptible chickens all chimeras replicated in the bursa of Fabricius (BF), and three chimeric viruses caused mild depletion of bursal cells. In contrast, after infection of chickens with a chimeric
Two different real-time polymerase chain reaction (PCR) detection approaches based on SYBR Green I dye and Taqman probe based assays were developed for the detection and differentiation of infectious bursal disease virus (IBDV) subtypes. Both approaches were able to detect and differentiate IBDV subtypes based on the use of subtype-specific primers or subtype-specific probes where the primers were designed based on single nucleotide polymorphism (SNP) concept. After optimization of the primer combinations and PCR parameters, very virulent-specific primer, IF & IVIR, and classical-specific primer, IF & RCLA were used in the SYBR Green I real-time RT-PCR assay. Plasmid DNA carrying the VP4 gene of the references IBDV strains: very virulent strain UPM94/273 and classical strain D78 were established and used as positive controls in the real time RT-PCR. The developed assay had a dynamic detection limit which spans over 5 log10 concentration range for very virulent and spans over 7 log10 ...
Infectious pancreatic necrosis virus (IPNV) is the aetiological agent of an important disease in hatchery-reared salmonid fish in North America, Europe and Japan. It belongs to the family Birnaviridae and shows a high degree of antigenic heterogeneity. However, genomic variations between the 10 identified serotypes have not yet been studied. In order to correlate genomic heterogeneity with the different serotypes, oligonucleotides were synthesized according to the published sequence of the Jasper strain (serotype A9). They were used as primers for the amplification of a 359 bp cDNA fragment of the viral genome using the polymerase chain reaction. Fragments amplified from 37 strains were digested with five different restriction enzymes. Restriction fragment profiles obtained on agarose gels showed heterogeneity not only between strains of different serotypes, but also among those belonging to serotype A1. A cluster analysis of the restriction patterns showed that IPNV strains can be divided into three
The present invention relates to a non pathogenic vaccine comprising a recombinant Infectious Bursal Disease virus that includes a recombinant Segment A, designated as rD78GLSNSΔ, that includes sequences from D78 and GLS strains and wherein the NS protein is not expressed.
Materials and methods. The bursae obtained from clinically normal indigenous scavenging chickens and IBD-confirmed dead broiler chickens from different farms were smeared directly onto separate filter papers, fixed with 99% ethanol and transported to Japan for molecular characterisation, as described previously (Kasanga et al. 2008; Maw et al. 2006).Total RNA was isolated from the bursal tissues fixed on filter papers and first-strand complementary DNAs were synthesised as described in a previous report (Kasanga et al. 2008). The VP2-HVRs were amplified by polymerase chain reaction (PCR) using the V1forward primer (5-CCAGAGTCTACACCATAA-3) and V2 reverse primer (3-TAGAAAGAGTGGCAACAGG-5) (Yamaguchi et al. 2007). The PCR products were cloned into the plasmid pGEM-T-Easy vector (Promega, Madison WI, USA) and cloned DNAs were sequenced at the Dragon Genomics Center (TAKARA Bio, Mie, Japan) using a Templiphi DNA sequencing Template Amplification Kit, DYEnamic ET dye terminator kit, and ...
Materials and methods. The bursae obtained from clinically normal indigenous scavenging chickens and IBD-confirmed dead broiler chickens from different farms were smeared directly onto separate filter papers, fixed with 99% ethanol and transported to Japan for molecular characterisation, as described previously (Kasanga et al. 2008; Maw et al. 2006).Total RNA was isolated from the bursal tissues fixed on filter papers and first-strand complementary DNAs were synthesised as described in a previous report (Kasanga et al. 2008). The VP2-HVRs were amplified by polymerase chain reaction (PCR) using the V1forward primer (5-CCAGAGTCTACACCATAA-3) and V2 reverse primer (3-TAGAAAGAGTGGCAACAGG-5) (Yamaguchi et al. 2007). The PCR products were cloned into the plasmid pGEM-T-Easy vector (Promega, Madison WI, USA) and cloned DNAs were sequenced at the Dragon Genomics Center (TAKARA Bio, Mie, Japan) using a Templiphi DNA sequencing Template Amplification Kit, DYEnamic ET dye terminator kit, and ...
Methods. Construction of the scFv Bacterial Displaying Library against Vp2. Immunization of Chicken: Three specific pathogen-free (SPF) chickens were immunized by intra-ocular administration of IBDV vaccine strain B-87 in the dose of 107pfu, the chickens were boosted one week later by intra-muscular injection with 0.5ml of formalin-inactivated preparation of B-87 emulsified with an equal volume of Freunds incomplete adjuvant. Four weeks after the secondary vaccination, the titer of immune serum was determined by ELISA, chickens were euthanized and spleens were collected for extraction of RNA by Trizol.. cdna Synthesis from Spleen Total Rna of The Immunized Chicken. Splenocytes were isolated from the immunized chicken for RNA extraction, and total RNA was extractd using Trizol. cDNA was synthesized from total RNA sample using Superscript II (Invitrogen) and random hexamer oligonucleotide pimers (2 μg). Construction of scFv library. Primers for scFv designed based on the variable region gene ...
Finnish Food Safety Authority Evira has completed a study conducted in fish farms between 2000 and 2015 to determine the genetic characteristics of the virus that causes infectious pancreatic necrosis (IPN) in fish. IPN is a viral disease which causes financial losses in aquaculture across the world. The mortality rate caused by the IPN virus in Finnish fish farms has so far remained low. The disease is not contagious to humans and fish are not used as food at the juvenile stage when they are vulnerable to the disease.. As the disease is highly contagious, it is important to determine any potential changes in the genome of the virus to facilitate the monitoring of the spreading of the disease and to prevent spreading both in the wild and in fish farms. The viral disease is particularly found in juvenile salmonids e.g. rainbow trout and Atlantic salmon, but other fish species can also become infected.. Since 1987, the IPN virus has been found every year in asymptomatic fish in the Finnish sea ...
Thinking about what has changed since the 1980s when although IPNV could be found in fish the actual disease condition was very rare. Over the last 2 decades considerable advances have been made in feed and feeding strategies, photoperiod manipulation and light exposure per se for salmon fry have produced smolting fish at different times of the year and much faster (I hesitate to say better) growth. In land-based freshwater rearing systems with the introduction of oxygen injection the stocking density has increased significantly in a number of farms; along with baseline carbon dioxide levels. So it could be argued that salmon in the 21st century are more highly "stressed" than their counterpart from the 20th Century. A bit like finely tuned athletes walking a fine line between health and disease susceptibility. Elite human athletes often fall prey to opportunistic and exotic pathogens such as colds and Epstein-Barr virus, the cause of Infectious mononucleosis or alternatively known as the ...
Cleavage sites.Two IPNV VP4 cleavage sites, located at the pVP2-VP4 and VP4-VP3 junctions, were identified by N-terminal sequence analysis of cleavage products produced in E. coli and probed by site-directed mutagenesis. They are characterized by the Ser-X-Ala↓Ser-Gly motif. Two other additional cleavage sites in the carboxyl part of pVP2 (P1 and P′1 positions 486 and 487 and positions 495 and 496) were first identified by sequence comparison (Fig. 10). The P1 and the P′2 residues appeared to be conserved as an alanine and a glycine, respectively. The P3 serine residue can substitute to a threonine (cleavage site positions 486 and 487), whereas the P′1 serine residue was notably substituted to an alanine. The cleavage between pVP2 and VP4 was abolished only when the Ala-Ser 508-509 and the two Ala-Ala 495-496 and 486-487 pairs were mutated together. These observations do not prove definitively the existence (and the functionality) of these two additional cleavage sites. However, these ...
Infectious bursal disease virus (IBDV) is a birnavirus that infects the B-cells in the bursa of Fabricius of young chickens, causing Gumboro disease. The IBDV 114 kDa polyprotein (NH2-pVP2-VP4-VP3-COOH) is thought to be ...
Infectious bursal disease virus (IBDV) is a birnavirus that infects the B-cells in the bursa of Fabricius of young chickens, causing Gumboro disease. The IBDV 114 kDa polyprotein (NH2-pVP2-VP4-VP3-COOH) is thought to be ...
Genome replication is a critical step in virus life cycles. Here, we analyzed the role of the infectious bursal disease virus (IBDV) VP3, a major component of ...
1. Fernandez R, Rojo F, Garcia H, Sanchez P, Martinez H, Menendez A, Ruiz H et al. Field efficacy in broiler chickens in Latin America of vHVT-013, a Mareks HVT vector vaccine expressing VP2 in infectious bursal disease virus. Oral presentation and abstract at the 15th congress of the World Veterinary Poultry Association, 2007; p199.. 2. Atienza JC, Nagera AJ, Martinez PO, Baysac ND, Castillo MT, Damaso VR, Lemière S. Evaluation of a herpesvirus of turkey vector vaccine inducing protection against infectious bursal and Mareks diseases (VAXXITEK® HVT+IBD) under Philippines field conditions. Oral presentation. XXIII World Poultry Congress, Brisbane, Australia. 2008. Article wpc0801684, 9 p.. 3. Garritty AT. The eff ect of vectored HVT+IBD (Vaxxitek® HVT + IBD) vaccination on body weights, uniformity and virus shedding in commercial broilers. Abstract. International Poultry Scientifi c Forum, Atlanta, 2011; p31.. 4. Godinho E, Pereira CJ, Fernandez A, Lemiere S. Case study of broiler chicken ...
Authors: Galloux, M.; Libersou, S.; Morellet, N.; Bouaziz, S.; Ouldali, M.; Da Costa, B.; Lepault, J.; Delmas, B.. Citation: Galloux, M.; Libersou, S.; Morellet, N.; Bouaziz, S.; Da Costa, B.; Ouldali, M.; Lepault, J.; Delmas, B.. "Infectious bursal disease virus, a non-enveloped virus, possesses a capsid-associated peptide that deforms and perforates biological membranes" J. Biol. Chem. 282, 20774-20784 (2007).. Assembly members: ...
Abcam provides specific protocols for Anti-Infectious Bursal Disease (Standard) (IBD) antibody (ab31672) : Immunohistochemistry protocols, Immunocytochemistry…
The avian industry needs solutions tailored to both smaller farms and integrated global operations dealing with high animal counts and labour-intensive practices. Merials vaccines effectively target the sectors biggest health threats, such as Mareks disease, infectious bursal disease, and avian flu. But equally important, we focus on innovative drug delivery mechanisms, diagnostic tools, and on-site consulting to support these on complex businesses in on going challenges ...
A cohabitation challenge model was developed for use in evaluating the efficacy of vaccines developed against infectious pancreatic necrosis virus (IPNV) in Atlantic salmon (Salmo salar L) using a stepwise approach. The study involved identifying a set of input variables that were optimized before inclusion in the model. Input variables identified included the highly virulent Norwegian Sp strain NVI015-TA encoding the T217A221 motif having the ability to cause |90% mortality and a hazard risk ratio of 490.18 (p|0.000) for use as challenge virus. The challenge dose was estimated at 1x107 TCID50/mL per fish while the proportion of virus shedders was estimated at 12.5% of the total number of fish per tank. The model was designed based on a three parallel tank system in which the Cox hazard proportional regression model was used to estimate the minimum number of fish required to show significant differences between the vaccinated and control fish in each tank. All input variables were optimized to generate
La bursite infectieuse aviaire (IBD) est une des causes majeures de pertes économiques pour lindustrie aviaire. La vaccination est le principal outil de contrôle de cette maladie et les oiseaux susceptibles doivent être vaccinés aussitôt que le niveau des anticorps maternels (MA) anti-IBDV est suffisamment bas. Lestimation du moment de vaccination est habituellement déterminée par la formule de Deventer qui utilise le titre initial de MA anti-IBDV et la demi-vie des anticorps pour prédire lévolution du titre. Dans la présente étude, leffet du gain de poids sur la vitesse de disparition des MA a été étudié dans le but de lutiliser pour prédire la détermination du moment de la vaccination. Lanalyse des taux danticorps neutralisants par ELISA a montré que les poussins avec une forte croissance avaient un taux de disparition plus rapide des MA que ceux à faible croissance. Une formule pour la prédiction du moment de vaccination contre le IBDV, basée sur le gain de poids ...
A reverse transcriptase polymerase chain reaction restriction fragment length polymorphism (RT-PCR/RFLP) technique was used for the identification and characterization of Pakistani field isolates of infectious bursal disease virus (IBDV). A total of 8 bursa samples were collected from two outbreaks during September and October 2003 from Tehsil Sumandri, Dist. Faisalabad with 40-50% mortality in commercially reared broiler chicken flocks experiencing signs typical of infectious bursal disease (IBD). Four samples were found to contain IBDV genome by One Step RT-PCR using VP2 gene specific primers. The assay amplified a 743 bp fragment from 701-1444 nucleotides. RT-PCR product was further subjected to restriction digestion using MboI and MvaI restriction enzymes. A third enzyme SspI was used to identify the very virulent phenotype. The RFLP profile was found similar for all four isolates with MvaI enzyme but different for one isolate when digested with MboI. All three MvaI-positive viruses were ...
The Birnaviridae genome encodes several proteins: Birnaviridae RNA-directed RNA polymerase (VP1), which lacks the highly conserved Gly-Asp-Asp (GDD) sequence, a component of the proposed catalytic site of this enzyme family that exists in the conserved motif VI of the palm domain of other RNA-directed RNA polymerases.[3] The large RNA segment, segment A, of birnaviruses codes for a polyprotein (N-VP2-VP4-VP3-C) [4] that is processed into the major structural proteins of the virion: VP2, VP3 (a minor structural component of the virus), and into the putative protease VP4.[4] VP4 protein is involved in generating VP2 and VP3.[4] recombinant VP3 is more immunogenic than recombinant VP2.[5] Infectious pancreatic necrosis virus (IPNV), a birnavirus, is an important pathogen in fish farms. Analyses of viral proteins showed that VP2 is the major structural and immunogenic polypeptide of the virus.[6][7] All neutralizing monoclonal antibodies are specific to VP2 and bind to continuous or discontinuous ...
Immunosuppressive viruses are frequently found as co-infections in the chicken industry, potentially causing serious economic losses. Because traditional molecular biology methods have limited detection ability, a rapid, high-throughput method for the differential diagnosis of these viruses is needed. The objective of this study is to develop a GenomeLab Gene Expression Profiler Analyser-based multiplex PCR method (GeXP-multiplex PCR) for simultaneous detection of eight immunosuppressive chicken viruses. Using chimeric primers, eight such viruses, including Mareks disease virus (MDV), three subgroups of avian leucosis virus (ALV-A/B/J), reticuloendotheliosis virus (REV), infectious bursal disease virus (IBDV), chicken infectious anaemia virus (CIAV) and avian reovirus (ARV), were amplified and identified by their respective amplicon sizes. The specificity and sensitivity of the optimised GeXP-multiplex PCR assay were evaluated, and the data demonstrated that this technique could selectively amplify
Infectious pancreatic necrosis virus (IPNV) is an aquatic member of the Birnaviridae family that causes widespread disease in salmonids. IPNV is represented by multiple strains with markedly different virulence. Comparison of isolates reveals hyper variable regions (HVR), which are presumably associated with pathogenicity. However little is known about the rates and modes of sequence divergence and molecular mechanisms that determine virulence. Also how the host response may influence IPNV virulence is poorly described. In this study we compared two field isolates of IPNV (NFH-Ar and NFH-El). The sequence changes, replication and mortality were assessed following experimental challenge of Atlantic salmon. Gene expression analyses with qPCR and microarray were applied to examine the immune responses in head kidney. Significant differences in mortality were observed between the two isolates, and viral load in the pancreas at 13 days post infection (d p.i.) was more than 4 orders of magnitude ...
PULLMAN, Wash. (AP) - Researchers say a serious new form of a viral poultry disease has been found in Washington state.Infectious bursal disease virus, known as IBDV for short, is not known to infe...
Vet Parasitol. 2013 Feb 18;192(1-3):98-103. doi: 10.1016/j.vetpar.2012.10.010. Epub 2012 Oct 23. Research Support, Non-U.S. Govt
Ol h, I., Magyar, A., Nagy, N., Horv th, E., Kov cs, A., Nagy, E. (2001): Effect of IBDV infection on the secretory dendritic cells. - In: van den Berg, T. (szerk.) EU Cost Action 839: International Symposium on Infectious Bursal Disease and Chicken Infectious Anemia. Office for Official Publication of the European Communities, Luxemburg, pp. 329-340 ...
Infectious Brusal Disease Virus Antibody Test Kit [IBD-2P] - Kit includes approximately 640 test samples plus controls, contains 5 microtiter plates. Infectious Bursal Disease (IBD) affects primarily young chickens. The condition is considered economically significant due its ability to induce profound immunosuppression in chickens often resulting in susceptibility to secondary bacterial and viral infections. The symptoms include depression, anorexia, ruffled feathers, and
A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for the rapid detection of equine coronavirus (ECoV). This assay was conducted at 60°C for 40min. Specificity of the RT-LAMP assay was confirmed using several equine intestinal and respiratory pathogens in addition to ECoV. The novel assay failed to cross-react with the other pathogens tested, suggesting i ...
I, Muhammad Sarwar Khan, am serving as Editor on Archives of Biotechnology and Biomedicine (ABB). I submitted an editorial titled, Edible vaccines to combat Infectious Bursal Disease of poultry for publication in ABB. After submitting the manuscript; the services rendered by the management and technical personnel to handle and process the manuscript were marvelous. Plagiarism report was shared with me with complements before reviewers comments, All steps including article processing and service charges were well taken care of keeping in view the authors interest/preference. All together, it was an encouraging and wonderful experience working with ABB personnel.. ...
Preparing for ABSITE Chair: Michael M. Awad, MD Faculty: Jeffrey Blatnik, MD; Amber Traugott, MD; and Adnan Alseidi, MD Program Outline: Welcome and Overview , Michael M. Awad, MD, PhD Esophagus, Stomach, Obesity , Michael M. Awad, MD, PhD General Abdomen, Hernia, Spleen , Jeffrey Blatnik, MD Colorectal & Anal Disease , Amber Traugott, MD […] ...
Does not work either. Also, your mailer destroys your patches. Le 20/02/2015 19:37, Steve Lhomme a écrit : , Heres one over the current master. Ill submit the other one after this , one is in, as it depends on it. , , --- , modules/demux/mkv/demux.cpp , 2 +- , modules/demux/mkv/matroska_segment.cpp , 12 ++++++------ , modules/demux/mkv/matroska_segment_parse.cpp , 14 +++++++------- , 3 files changed, 14 insertions(+), 14 deletions(-) , , diff --git a/modules/demux/mkv/demux.cpp b/modules/demux/mkv/demux.cpp , index 1feca55..21618f4 100644 , --- a/modules/demux/mkv/demux.cpp , +++ b/modules/demux/mkv/demux.cpp , @@ -519,7 +519,7 @@ matroska_stream_c , *demux_sys_t::AnalyseAllSegmentsFound( demux_t *p_demux, EbmlS , // find the families of this segment , KaxInfo *p_info = static_cast,KaxInfo*,(p_l1); , b_keep_segment = b_initial; , - if( unlikely( p_info-,GetSize() ,= SIZE_MAX ) ) , + if( unlikely( p_info-,IsFiniteSize() && , p_info-,GetSize() ,= SIZE_MAX ) ) , { , msg_Err( p_demux, KaxInfo ...
Line graphs showing the results of numerical simulation of the temporal evolution of the output power of a Tm3+:ZBLAN fiber laser and the temporal evolution of the energy level population of the Tm3+ ions ...
In farms, mortalities occur mainly in the fry (or juvenile) stages, but in recent years Atlantic salmon post-smolts have suffered considerable mortalities from IPN, especially in Norway and Scotland. All age groups of fish, in both fresh and sea water environments can be infected asymptomatically and may shed virus.. In Scotland, the prevalence of IPNV infection is very high in famed Atlantic salmon in sea water. In freshwater salmon farms, the prevalence of infection and incidence of disease is considerably lower, but has increased in recent years.. ...
Researchers at The Pirbright Institute have created a new method of genetically modifying the Mareks disease vaccine so that it is able to protect against another destructive poultry virus called infectious bursal disease (IBD), and potentially others such as avian influenza and Newcastle disease. This approach could lead to a reduction in the number of vaccines that need to
Poultry Diagnostics Market Analysis By Test Types (ELISA, PCR), By Disease Type (Avian Salmonellosis, Avian Influenza, Newcastle Disease, Infectious Bursal Disease, Avian Encephalomyelitis,
Antibodies are other respectable achievements of our R&D experts, recognized by Vietnam Ministry of Science and Technology. Among that, HANVET K.T.G is a sterile emulsion, containing specific antibodies against infectious bursal disease (IBD), Newcastle disease (ND) and Infectious bronchitis (IB) in chickens; that obtained from hyper-immunized hen egg-yolk. In addition, the preparation acts as a non-specific protein-therapy and increases the bodys resistance to prevent infections and secondary infections. HANVET K.T.G has also been recognized by the first prize of VIFOTEC 2007 for a creative bio-product and the second prize at Korean International Expo in 2007 ...
TY - JOUR. T1 - Clinical impact of EUS treatment of walled-off pancreatic necrosis with dedicated devices. AU - Tarantino, Ilaria. AU - Ligresti, Dario. AU - Tuzzolino, Fabio. AU - Barresi, Luca. AU - Curcio, Gabriele. AU - Granata, Antonino. AU - Traina, Mario. PY - 2017/8. Y1 - 2017/8. N2 - BACKGROUND AND STUDY AIMS: Walled-off pancreatic necrosis (WOPN) represents the major risk factor for sepsis-related multiple organ failure. Surgical debridement is an invasive approach associated with high rates of adverse events (AEs) and death. As an alternative, endoscopic ultrasound-guided cysto-gastro-anastomosis has emerged as an effective treatment for WOPNs. Recently a new dedicated-lumen apposing metal stent (LAMS) has been used with satisfactory results in treating peri-pancreatic fluid collections, including WOPNs. The primary outcomes of this study were to evaluate survival and clinical success. Secondary outcomes included: technical success, adverse events and recurrence rate.PATIENTS AND ...
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
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There is increasing concern about the impact of veterinary drugs and livestock pathogens as factors damaging wildlife health, especially of threatened avian scavengers feeding upon medicated livestock carcasses. We conducted a comprehensive study of failed eggs and dead nestlings in bearded vultures (Gypaetus barbatus) to attempt to elucidate the proximate causes of breeding failure behind the recent decline in productivity in the Spanish Pyrenees. We found high concentrations of multiple veterinary drugs, primarily fluoroquinolones, in most failed eggs and nestlings, associated with multiple internal organ damage and livestock pathogens causing disease, especially septicaemia by swine pathogens and infectious bursal disease. The combined impact of drugs and disease as stochastic factors may result in potentially devastating effects exacerbating an already high risk of extinction and should be considered in current conservation programs for bearded vultures and other scavenger species, especially in
Pancreatic necrosis treatment at Virginia Mason, in Seattle Washington. Pancreatic necrosis is a serious infection usually associated with acute pancreatitis.
Listing your company for Pharmaceutical & Laboratory Machinery allows buyers to find your information through our directory pages which appear in the top positions when a search is conducted in Google, Yahoo!, MSN etc ...
Pancreatic necrosis is a form of severe pancreatitis associated with high morbidity and mortality. In this condition there is necrosis of pancreatic tissue with pancreatic duct disruption leading to r
Rothiamucilaginosa, previously known as Stomatococcus mucilaginous, resides in the oral cavity and respiratory tract as part of the normal flora [1]. It is a gram-positive, cocus-shaped bacterium. The bacterium is considered an emerging opportunistic pathogen in patients with chronic immunosuppressive diseases. Most of these reports were described in severe neutropenia or hematological cancer patients but less frequently in immune-competent hosts. We report two cases of endocarditis and meningitis due to R. mucilaginosain non-neutropenic hosts.
Infectious pancreatic necrosis (IPN) is an acute, contagious disease of trout fry and fingerlings caused by viruses of the family birnaviridae. IPN disease usually results in mortality that is inversely proportional to the age of the fish. While many studies have been carried out to increase our understanding of IPN, little is known about its virulence characteristics for some subtypes common to the Pacific Northwest region of the United States. Knowledge of relationships between IPN virus subtypes, epitope patterns and virulence patterns could be useful for developing a successful IPNV vaccine. This study investigated virulence characteristics of IPN viruses in brook trout, Salvelinus fontinalis, fry, using fish mortality, virus titer in fish tissue, and the presence of clinical signs of IPN as indicators of virulence. The relationship between virulence and different IPN virus subtypes, and specific epitopes, or monoclonal antibody binding sites, was also addressed. An additional study focused ...
Pathologic lymph node staging is becoming a deficient method in the demanding molecular era. Nevertheless, the use of more sensitive molecular analysis for nodal staging is hampered by its high costs and extensive time requirements. Our aim is to take a step forward in colon cancer (CC) lymph node (LN) pathology diagnosis by proposing a feasible and efficient molecular method in routine practice using reverse transcription loop-mediated isothermal amplification (RT-LAMP). Molecular detection of tumor cytokeratin 19 (CK19) mRNA with RT-LAMP was performed in 3206 LNs from 188 CC patients using two methods: individual analysis of 1449 LNs from 102 patients (individual cohort), and pooled LN analysis of 1757 LNs from 86 patients (pooling cohort). A median of 13 LNs (IQR 10-18) per patient were harvested in the individual cohort, and 18 LNs (IQR 13-25) per patient in the pooling cohort (p ≤ 0.001). The median of molecular assays performed in the pooling cohort was 2 per patient (IQR 1-3), saving a median
Background and aims: Medicinal plant products are considered to be an effective candidate against the number of viral diseases as generally observed or reported in developing countries. As per the literature, secondary metabolites (i.e. Alkaloids, flavonoids, saponins etc.) are reported in medicinal plant products and showed its antiviral properties. In this study, our group focused on those medicinal plants especially roots of Ficus benghalensis and Ficus racemosa related to New castle Disease Virus (NDV) and Infectious Bursal Disease (IBD) having in vitro antiviral activity. These studies were conducted on the human peripheral blood mononuclear cells (PBMC). Methods: For antimicrobial studies, different medicinal plant products especially roots of Ficus benghalensis and Ficus racemosa were collected from Vidya Pratishthans garden, School of Biotechnology, Baramati. These medicinal plant leaves are used in the form of aqueous extract and determined its anti-microbial activity against poultry viruses
An expanding gate valve according to the present invention includes a gate system incorporating a pair of segments, one segment being formed to define opening cam surface means and the other segment b
... Prosser Commits Suicide Posted by CN Staff on October 25, 2007 at 05:49:27 PT By Jessie McQuillan Source: Missoula Independent Montana -- Robin Prosser didn t look or sound much like a fighter, but she was. A mother and a musician, the Missoula woman also acted as Montana s most outspoken advocate for medical marijuana, the only remedy that could ease the ravaging pain of the lupus-like immunosuppressive disease she endured for 23 years. Prosser s fight ended Oct. 18 when she took her own life. In recent months, Prosser, 50, would sit at the kitchen table in her small apartment, pain welling up in her eyes, and talk quietly about the victories and defeats the last several years had delivered. Allergic to nearly every pharmaceutical that could render her chronic pain bearable, she had learned that the political fate of medical marijuana also carried intensely personal implications. She remained proud of the 60-day hunger strike she undertook in 2002 to ...
If the blast-like cell population is exhausted after IBDV infection or testosterone treatment, regeneration of the follicle, but not the entire bursa, is handicapped. The cytological structure of the cortico-medullary and FAE-supportive epithelial cells is quite different. The former are rich in cytoplasmic organelles and their cytoskeletal keratin filaments outline the arch shape of the cells, while FAE-supportive cells form 2-3 squamous cell layers that are rich in keratin with few organelles. 1993b; Mast and Goddeeris, 1998b). Ellipsoids and PWP Penicillar capillaries lack muscular layers, have stomata and are lined with cuboidal endothelium. The mid-portion of the capillary is surrounded by the ellipsoid which is an efficient filtration apparatus with mechanical filtration carried out by the extracellular matrix and phagocytic filtration by cellular components. 1). The basal membrane and the CSS are interconnected with fine reticular fibres, forming a three-dimensional network. Intravenously ...
I am going to be buying or building a coop for my 4 week to 10 week old chicks. Like something that will get them out of the house and garage, but...
The Lasher Laboratory enhances the University of Delawares ability to respond quickly and efficiently to industry needs for poultry disease diagnosis and outreach activities. Diagnostic services available at the Lasher Laboratory include poultry necropsy and clinical diagnosis, bacteriology, mycology, molecular diagnostic testing, and serology. Virology and histopathology specimens collected at the laboratory are sent to the Newark campus for evaluation. The Lasher Laboratory conducts applied research on poultry diseases, often in collaboration with poultry industry scientists, and provides a broiler progeny challenge service for evaluating infectious bursal disease virus vaccinal immunity. As a NALHN approved laboratory, the Lasher Laboratory routinely performs surveillance for avian influenza and exotic Newcastle disease. Avian influenza surveillance programs include pre-slaughter testing of commercial broiler chickens, routine surveillance of backyard flocks, and testing of diseased flocks. ...
During a period of two years, 599 samples of rainbow trout (S. gairdneri)(71%), brown trout (Salmo trutta)(14%), brook trout (Salvelinus fontinalis)(1%), Atlantic salmon (Salmo salar)(2%), and various species (12%), were analysed. The viral haemorrhagic Septicaemia (V.H.S.) virus is present in about 6% of samples from 15 piscicultures and infectious pancreatic necrosis virus is present in about 42% of samples from the 55 piscicultures regularly inspected in Aquitaine. ...
Amakye-Anim, J., T. Lin, P. Hester, et al. (2000) Ascorbic acid supplementation improved antibody response to infectious bursal disease vaccination in chickens. Poultry Science 79:680-688. Azad, I., J. Dayal, M. Poornima, and S. Ali (2007) Supra dietary levels of vitamins C and E enhance antibody production and immune memory in juvenile milkfish, Chanos chanos (Forsskal) to formalin-killed Vibrio vulnificus. Fish & Shellfish Immunology 23:154-163. Carroll, R., K. Kovacs, and E. Tapp (1965) Protection against mercuric chloride poisoning of the rat kidney. Arzneimittelforschung 15:1361-1363. Feigen, G., B. Smith, C. Dix, et al. (1982) Enhancement of antibody production and protection against systemic anaphylaxis by large doses of vitamin C. Research Communications in Chemical Pathology and Pharmacology 38:313-333. Gage, J. (1975) Mechanisms for the biodegradation of organic mercury compounds: the actions of ascorbate and of soluble proteins. Toxicology and Applied Pharmacology ...
Acute pancreatitis is sudden swelling and inflammation. We provide best services for acute pancreatitis treatment and pancreatic necrosis treatment in Kochi, Kerala
Only a minority of probable SARS cases caused transmission. We assess if any epidemiological or clinical factors in SARS index patients were associated with increased probability of transmission. We used epidemiological and clinical data on probable SARS patients admitted to Tan Tock Seng Hospital. Using a case-control approach, index patients who had probable SARS who subsequently transmitted the disease to at least one other patient were analysed as cases against patients with no transmission as controls, using multivariate logistic regression analysis. 98 index patients were available for analysis (22 with transmission, 76 with no transmission). Covariates positively associated with transmission in univariate analysis at p | 0.05 included delay to isolation (Day 7 of illness or later), admission to a non-isolation facility, pre-existing chronic respiratory disease and immunosuppressive disease, need for oxygen, shortness of breath, vomiting, and higher lactate dehydrogenase levels and higher
Empyema caused by Kingella denitrificans and Peptostreptococcus spp. was diagnosed in a patient with bronchogenic carcinoma. This appears to be the third report providing evidence of a pathogenic role for K. denitrificans, and the first concerning infection in the pleural space and in a patient with underlying immunosuppressive disease. K. denitrificans should be added to the list of fastidious gram-negative bacteria associated with opportunistic infections in the compromised host.. ...
Inside the body, bursa are sacs filled with a lubricating fluid. They reduce friction between different tissues and provide a cushion against pressure. Bursa are found between bodily structures like...
Length of stay (ICU, hospital) Mortality .. RESULTS: We studied the outcome of 15 cases of infected pancreatic necrosis managed by laparoscopic pancreatic necrosectomy as regards morbidity, length of stay & mortality.. In present study transperitoneal approach access to lesser sac, right and left paracolic gutter, perinepheric space, retroduodenal space & root of mesentery was accomplished for drainage.. Each patients treatment was individualized & preoperative CT scan guided the approach.. Stay of patients was average 8 days, 10 developed pancreatic fistula, all required irrigation which was taught to patients relatives.. 2 patients required laparotomy. 2 others required pigtail drainage of residual collections by CT guided radiological drains.. There was one mortality.. CONCLUSIONS: Laparoscopic necrosectomy is a feasible procedure in acute infected pancreatic necrosis. We report similar rate of complications as open necrosectomy but with less morbidity to the patients. ...
I work as a researcher in the field of Fish health. My work implies project and contract research within the areas of pathogen-host interactions and vaccine development I am responsible for the infectious pancreatic necrosis (IPN) challenge model primarily used in contract research for the fish vaccine industry. I am a M. Sc. with some supplementary education from University of Tromsø. My working experience is from fish health research and the fish vaccine industry. For many years I have worked with different problem areas concerning Atlantic salmon and IPN. I also work with intracellular bacteria causing diseases in fish.. ...
There were more Vanessa cardui butterflies around the Green-Wood Buddleja planting than Ive ever seen in one place in New York City.Really nice to see so many individuals of slightly different sizes and color intensity.What is up with this hanging out on the stone or tarmac?
Helpful, trusted answers from doctors: Dr. Friedlander on lotus stem necrosis virus: German researchers are looking at this idea using rats that suffered brain damage from too little oxygen. Their results are promising. However, even if it works out well in similar studies, it will be several years before it would be tested in humans.
chronic infection in adult, and acute viral disease in young salmonid fish.[1][2] ... Birnaviridae proteins[edit]. The Birnaviridae genome encodes several proteins: Birnaviridae RNA-directed RNA polymerase (VP1), ... Birnaviridae is a family of viruses. Salmonid fish, young sexually immature chickens, and insects serve as natural hosts. There ... Viruses in Birnaviridae are non-enveloped, with icosahedral and Single-shelled geometries, and T=13 symmetry. The diameter is ...
chronic infection in adult, and acute viral disease in young salmonid fish. Group: dsRNA Order: Unassigned Family: Birnaviridae ... Aquabirnavirus is a genus of viruses, in the family Birnaviridae. Salmonid fish serve as natural hosts. There are currently ...
Resistance to infection develops more rapidly in warmer water. It is highly contagious and found worldwide, but some regions ... It is caused by infectious pancreatic necrosis virus, which is a member of the Birnaviridae family. This disease mainly affects ...
... may be susceptible to opportunistic infection and may die of infection by agents that would not usually cause disease in ... is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus Avibirnavirus of family Birnaviridae. ... Infection is via the oro-fecal route, with affected bird excreting high levels of the virus for approximately 2 weeks after ... Passive immunity may protect against challenge with homologous IBDV, as does previous infection with homologous avirulent ...
... (DXV) belongs to the Birnaviridae family of viruses. Birnaviridae currently consists of three genera. The ... Infection studies with DXV has shed light on the innate immune response and RNA interference (RNAi) in Drosophila flies. ... This polypeptide is 977 amino acids in length, making it the largest encoded RdRp in the Birnaviridae family. The RdRp contains ... Although widely used in the laboratory, DXV has never been found as a natural infection of Drosophila, and was originally ...
Proper infection and production of progeny requires that the cell be in replication, as it is during replication that the ... This family is also not as well-studied as the rest and includes 2 major families, the Reoviridae and Birnaviridae. Replication ...
It then injects its DNA or RNA into the host to initiate infection. The cell membrane of the host cell invaginates the virus ... This class includes two major families, the Reoviridae and Birnaviridae. Replication is monocistronic and includes individual, ... Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must ...
Infection prevention and control during health care for probable or confirmed cases of novel coronavirus (nCoV) infection (PDF) ... 双DNA病毒科 Birnaviridae. *金色病毒科 Chrysoviridae. *囊状噬菌体科 Cystoviridae ... WHO: Novel coronavirus infection. 2013-02-11 [2013-02-13].. *^ James Gallagher. Coronavirus: Signs the new Sars-like virus can ... Camel infection 'led to Mers death'. BBC News. 2014-06-05 [2014-06-05].. ...
As such, purified RNA of a positive-sense virus can directly cause infection though it may be less infectious than the whole ... Family Amalgaviridae Family Birnaviridae Family Chrysoviridae Family Cystoviridae Family Endornaviridae Family Hypoviridae ... Birnaviridae and Cystoviridae, Nodaviridae, and Permutotretraviridae families. A number of satellite viruses - viruses that ... "Viral Evolution and Escape during Acute HIV-1 Infection". J. Infect. Dis. 202 (Suppl 2): S309-14. doi:10.1086/655653. PMC ...
Breuil, G., Bonami, J.R., Pepin, J.F., and Pichot, Y. (1991). Viral infection (picorna-like virus) associated with mass ... Mechanisms of Capsid Assembly and Viral Infection. PLoS Pathogens 11(10), e1005203. ...
The presence of IgM in the blood of the host is used to test for acute infection, whereas IgG indicates an infection sometime ... Vaccination is a cheap and effective way of preventing infections by viruses. Vaccines were used to prevent viral infections ... Smallpox infections have been eradicated.[196] Vaccines are available to prevent over thirteen viral infections of humans,[197] ... Hepatitis viruses can develop into a chronic viral infection that leads to liver cancer.[179][180] Infection by human T- ...
But, unlike other viral infections, the incidence of polio - the rarer severe form of the infection - increased in the 20th ... Many bacteriologists soon discovered the cause of numerous infections. However, some infections remained, many of them ... Ivanovsky suggested the infection might be caused by a toxin produced by bacteria, but did not pursue the idea.[3] ... Infections by poliovirus most often cause the mildest of symptoms. This was not known until the virus was isolated in cultured ...
Feline leukemia virus and Feline immunodeficiency virus infections are treated with biologics, including the only ... At that point, the infection will persist indefinitely. In most viruses, DNA is transcribed into RNA, and then RNA is ... As a result, cells such as neurons are very resistant to infection and transduction by retroviruses. This gives rise to a ... Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. Different classes of ...
Birnaviridae Genus: Aquabirnavirus Infectious pancreatic necrosis virus Tellina virus Yellowtail ascites virus Genus: ... Viruses portal Virus Virology Virus classification List of latent human viral infections Table of clinically important viruses ...
Hepatis B Virus (HBV) was identified as an infection distinct from Hepatitis A through its contamination of measles, mumps, and ... Diseases associated with this family include: liver infections, such as hepatitis, hepatocellular carcinomas (chronic ... cell to infect others or are immediately dismantled so the new viral genomes can enter the nucleus and magnify the infection. ...
Without the virus infection, phagocytic hemocytes (blood cells) will encapsulate and kill the wasp egg and larvae but the ... The infection does not lead to replication of new viruses, rather it affects the caterpillar's immune system. ...
Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and ...
chronic infection in adult, and acute viral disease in young salmonid fish.[1][2] ... Birnaviridae proteins[edit]. The Birnaviridae genome encodes several proteins: Birnaviridae RNA-directed RNA polymerase (VP1), ... Birnaviridae is a family of viruses. Salmonid fish, young sexually immature chickens, and insects serve as natural hosts. There ... Viruses in Birnaviridae are non-enveloped, with icosahedral and Single-shelled geometries, and T=13 symmetry. The diameter is ...
Animals , Birnaviridae Infections/immunology , Bursa of Fabricius/immunology , CD4-Positive T-Lymphocytes/immunology , CD8- ... Animals , Birnaviridae Infections/veterinary , Chickens , Infectious bursal disease virus/immunology , Poultry Diseases/ ... Animals , Birnaviridae Infections/immunology , Chickens , Cyclosporine/pharmacology , Disease Models, Animal , ... Animals , Antibodies, Viral/blood , Birnaviridae Infections/immunology , Chickens , Egg Yolk/immunology , Enzyme-Linked ...
Our findings suggest that IPNv infection increase oxidative stress on headkidney as a consequence of iron overload induced by a ... Our findings suggest that IPNv infection increase oxidative stress on headkidney as a consequence of iron overload induced by a ... While immune modulation induced by IPNv infection has been widely characterized on Salmo salar, viral impact on iron host ... While immune modulation induced by IPNv infection has been widely characterized on Salmo salar, viral impact on iron host ...
Birnaviridae Infections/diagnosis , Birnaviridae Infections/genetics , Birnaviridae Infections , Salmonidae , Fluorescent ... Chick Embryo , Birnaviridae Infections , Chick Embryo , In Vitro Techniques , Infectious bursal disease virus , Methods , ... Animals , Birnaviridae Infections , Virology , Chickens , Infectious bursal disease virus , Genetics , Physiology , Poultry ... Animals , Birnaviridae Infections , Genetic Variation , In Vitro Techniques , Phylogeny , Polymerase Chain Reaction , ...
Birnaviridae. *Birnaviridae infections. *birnavirus. *Birnbaum - Saunders Distribution. *Birnbaum Interpreting Services. * ...
Animals , Antibodies, Viral , Birnaviridae Infections/prevention & control , Cells, Cultured , Chick Embryo , Chickens , ... Birnaviridae Infections / Infectious bursal disease virus Language: English Journal: Journal of Veterinary Science Year: 2012 ...
The blotched snakehead (BSN) cell line associated virus was shown to be a new member of the family Birnaviridae and was also ... Studies on virus infections of food fish in the Indo-Pacific region. Final Project Report, University of Stirling, UK, 15 pp. ... Studies on virus infections of food fish in the Indo-Pacific region. Final Project Report. ... Studies on virus infections of food fish in the Indo-Pacific region. Final Project Report. ...
Birnaviridae. *Birnaviridae infections. *birnavirus. *Birnbaum - Saunders Distribution. *Birnbaum Interpreting Services. * ...
Animals, Birnaviridae Infections, pathology, veterinary, virology, Bursa of Fabricius, Chickens, Infectious bursal disease ... Experimental infection of laboratory-bred bank voles (Myodes glareolus) with murid herpesvirus 4.. 2012 David J Hughes et al. ... Differential expression of the Toll-like receptor pathway and related genes of chicken bursa after experimental infection with ... Animal Structures, pathology, virology, Animals, Arvicolinae, Herpesviridae Infections, veterinary, Mice, Mice, Inbred BALB C, ...
Birnaviridae; Hepadnaviridae (Hepatitis B virus); Parvoviridae (parvoviruses); Papovaviridae (papilloma viruses, polyoma ... Persistent infections can be chronic infections, latent infections, or slow infections. Latent infection is characterized by ... Persistent infections include for example, latent, chronic and slow infections. Persistent infection occurs with viruses such ... In additional examples, the subject has an infection, such as a persistent infection. A subject with a persistent infection can ...
chronic infection in adult, and acute viral disease in young salmonid fish. Group: dsRNA Order: Unassigned Family: Birnaviridae ... Aquabirnavirus is a genus of viruses, in the family Birnaviridae. Salmonid fish serve as natural hosts. There are currently ...
Resistance to infection develops more rapidly in warmer water. It is highly contagious and found worldwide, but some regions ... It is caused by infectious pancreatic necrosis virus, which is a member of the Birnaviridae family. This disease mainly affects ...
During infection, rigid tubes 55 nm in diameter are formed by preVP2. In the case of IBDV, additional tubules 25 nm in diameter ... Birnaviridae: from Latin prefix bi, "two", signifying the bisegmented nature of the viral genome as well as the presence of ... Birnaviridae is a family of viruses with bisegmented dsRNA genomes with a total of about 6 kbp forming icosahedral, non- ... Figure 4.Birnaviridae. A distance tree representing the phylogenetic relationships of VP1 for members of the various genera and ...
Arenaviridae Infections. *Astroviridae Infections. *Birnaviridae Infections. *Bunyaviridae Infections. *Caliciviridae ... "Arenaviridae Infections" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Arenaviridae Infections" by people in this website by year, ... Regulation of tissue-dependent differences in CD8+ T cell apoptosis during viral infection. J Virol. 2014 Sep 1; 88(17):9490- ...
The Pathogenesis of Virus Infections 4. Antiviral Immunity and Prophylaxis 5. The Diagnosis of Virus Infections 6. The ... Birnaviridae 17. Paramyxoviridae 18. Rhabdoviridae 19. Filoviridae 20. Bornaviridae 21. Orthomyxoviridae 22. Bunyaviridae 23. ... partI presents the fundamental principles of virology related to animal infection and disease, and partII addresses the ... Epidemiology of Virus Infections. PART II: VETERINARY AND ZOONOTIC VIRUSES 7. Poxviridae 8. Asfarviridae and Iridoviridae 9. ...
Animals, Birnaviridae Infections, veterinary, virology, Chickens, Cluster Analysis, Genotype, Infectious bursal disease virus, ...
VP5 inhibits apoptosis at the early stage of viral infection in chicken embryonic fibroblast cells, whereas VP2 induces ... depletion of B cells in the bursa of Fabricius leads to immunosuppression and increased susceptibility to other infections and ...
... may be susceptible to opportunistic infection and may die of infection by agents that would not usually cause disease in ... is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus Avibirnavirus of family Birnaviridae. ... Infection is via the oro-fecal route, with affected bird excreting high levels of the virus for approximately 2 weeks after ... Passive immunity may protect against challenge with homologous IBDV, as does previous infection with homologous avirulent ...
Mechanisms of Infection and Viral Spread through the Body *Determinants of Viral Virulence and Host Resistance ...
Infectious pancreatic necrosis virus (IPNV) is an aquatic member of the Birnaviridae family that causes widespread disease in ... and viral load in the pancreas at 13 days post infection (d p.i.) was more than 4 orders of magnitude greater for NFH-Ar in ... IPNV with high and low virulence: host immune responses and viral mutations during infection. Permanent lenke. http://hdl. ...
Animals , Salmonidae/virology , Infectious pancreatic necrosis virus/isolation & purification , Birnaviridae Infections/ ... Birnaviridae Infections/virology , Aquaculture , False Negative Reactions , False Positive Reactions , Fish Diseases/virology ...
Double stranded RNA , RNA , Active sites , Birnaviridae infections , Infectious bursal disease virus , Thumb , Crystals , ... Infections , Fungal infections , Antiinfectives and antibacterials , Blood , Microorganisms , Etiology , Bacterial infections ... Bacterial Infections - etiology , Humans , Bacterial Infections - epidemiology , Bacteria - classification , Organ Preservation ... SOLID-ORGAN TRANSPLANTATION , SURVIVAL , CRITERIA , INFECTIONS , MULTIDISCIPLINARY SCIENCES , POSITIVE CULTURES , BACTERIAL , ...
Animals , Antibodies, Viral , Birnaviridae Infections/prevention & control , Cells, Cultured , Chick Embryo , Chickens , ...
Animals, Laboratory , Animals , Birnaviridae Infections/diagnosis , Chickens , Infectious bursal disease virus/classification ... Animals , Vaccines, Attenuated , Drug Administration Routes , Birnaviridae Infections/prevention & control , Enzyme-Linked ... Chicken meat and egg are two important sources of SE infection for humans. This study was conducted to detect the SE infection ... Animals , Salmonella Infections/blood , Poultry , Enzyme-Linked Immunosorbent Assay , Agglutination Tests , Serology ...
Birnaviridae Infections/mortality , Birnaviridae Infections/pathology , Birnaviridae Infections/physiopathology , Birnaviridae/ ... Animals , Birnaviridae Infections/immunology , Bursa of Fabricius/immunology , CD4-Positive T-Lymphocytes/immunology , CD8- ... Animals , Birnaviridae Infections/veterinary , Chickens , Infectious bursal disease virus/immunology , Poultry Diseases/ ... Animals , Antibodies, Viral/blood , Birnaviridae Infections/immunology , Chickens , Egg Yolk/immunology , Enzyme-Linked ...
  • The Synthetic AMS got from reaction of Aluminum silicate and Magnesium silicate has exhibited antiviral effects against all four viral families, so far tested, including, Paramyxoviridae, Birnaviridae, Parvoviridae and Othomyxoviridae . (scirp.org)
  • Fully revised and updated by the new author team, partI presents the fundamental principles of virology related to animal infection and disease, and partII addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases. (barnesandnoble.com)
  • Birnaviridae RNA-directed RNA polymerase (VP1), which lacks the highly conserved Gly-Asp-Asp (GDD) sequence, a component of the proposed catalytic site of this enzyme family that exists in the conserved motif VI of the palm domain of other RNA-directed RNA polymerases. (wikipedia.org)
  • the activation of the Toll-mediated response to microbial infections and the prophenoloxydase cascade, which triggers melanization. (cnrs.fr)
  • This study aimed to evaluate the efficacy of fructose-1,6-bis phosphate aldolase (SMALDO) DNA vaccination against Schistosoma mansoni infection using different routes of injection. (bvsalud.org)
  • many of them may cause bursal atrophy and thus immunosuppression with poor immune response to vaccination against other pathogens and an increase in vulnerability to various types of infections . (heighpubs.org)
  • A Drosophila melanogaster systemic infection model for the microsporidian Tubulinosema ratisbonensis reveals that the parasite hijacks host phosphatidic acid, which is a limiting precursor for synthesis of parasite membranes and therefore proliferation. (cnrs.fr)
  • Significant differences in mortality were observed between the two isolates, and viral load in the pancreas at 13 days post infection (d p.i.) was more than 4 orders of magnitude greater for NFH-Ar in comparison with NFH-El. (uit.no)
  • At week 8 post-infection, animals were sacrificed for assessment of parasitological and histopathological parameters. (bvsalud.org)
  • We review here recent developments, from the sensing of viral infection to the induction of signaling pathways and production of antiviral effector molecules. (cnrs.fr)
  • From the findings of necropsy and histopathology, systemic infection was diagnosed by Aspergillus sp. (bvsalud.org)
  • 11. The method of claim 1 wherein the agent is co-administered with at least one additional therapy used to treat a bacterial infection. (patentsencyclopedia.com)
  • 12. A method of treating a bacterial infection in a subject in need thereof, the method comprising administering an agent that increases the activity of RNase-L, wherein said agent is a nucleic acid comprising cathepsinE mRNA or a 2',5'-linked oligoadenylate (2-5A) mRNA. (patentsencyclopedia.com)
  • Experimental infection of laboratory-bred bank voles (Myodes glareolus) with murid herpesvirus 4. (naver.com)
  • Accumulating evidence has indicated that treatment efficacy during experimental infection with T. cruzi results from the combined action of BZ and the activation of appropriate immune responses in the host. (bvsalud.org)
  • While immune modulation induced by IPNv infection has been widely characterized on Salmo salar , viral impact on iron host metabolism has not yet been elucidated. (frontiersin.org)
  • Our findings suggest that IPNv infection increase oxidative stress on headkidney as a consequence of iron overload induced by a massive upregulation of genes involved in iron metabolism. (frontiersin.org)
  • The current study aims to screen the epidemiological status and molecular phylogeny of HBoV isolates prevailing in pediatric patients with respiratory infection in Saudi Arabia. (datexis.com)
  • Among the factors predisposing to the reported systemic fungal infection, the patient's weakened immune status is highlighted, possibly due to prolonged antibiotic and steroidal anti-inflammatory treatments. (bvsalud.org)
  • But in some people - especially children, older adults and people with compromised immune systems - norovirus infection can cause dehydration. (ecohealth2018.co)
  • A single dose of HZ DNA vaccine strongly boosted gE-specific T-cell responses in mice with a history of previous infection by VV-gE. (bvsalud.org)