Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.Antimanic Agents: Agents that are used to treat bipolar disorders or mania associated with other affective disorders.Lithium Compounds: Inorganic compounds that contain lithium as an integral part of the molecule.Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.Lithium Carbonate: A lithium salt, classified as a mood-stabilizing agent. Lithium ion alters the metabolism of BIOGENIC MONOAMINES in the CENTRAL NERVOUS SYSTEM, and affects multiple neurotransmission systems.Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.Diagnostic and Statistical Manual of Mental Disorders: Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)Psychiatric Status Rating Scales: Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.Anxiety Disorders: Persistent and disabling ANXIETY.Depressive Disorder, Major: Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.Antipsychotic Agents: Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)Valproic Acid: A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.Affect: The feeling-tone accompaniment of an idea or mental representation. It is the most direct psychic derivative of instinct and the psychic representative of the various bodily changes by means of which instincts manifest themselves.Irritable Mood: Abnormal or excessive excitability with easily triggered anger, annoyance, or impatience.Cyclothymic Disorder: An affective disorder characterized by periods of depression and hypomania. These may be separated by periods of normal mood.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Psychotropic Drugs: A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.Cognition Disorders: Disturbances in mental processes related to learning, thinking, reasoning, and judgment.Substance-Related Disorders: Disorders related to substance abuse.Antidepressive Agents: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.Neuropsychological Tests: Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Suicide, Attempted: The unsuccessful attempt to kill oneself.Lithium Chloride: A salt of lithium that has been used experimentally as an immunomodulator.Prefrontal Cortex: The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.Gyrus Cinguli: One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.Postmortem Changes: Physiological changes that occur in bodies after death.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Diagnosis, Dual (Psychiatry): The co-existence of a substance abuse disorder with a psychiatric disorder. The diagnostic principle is based on the fact that it has been found often that chemically dependent patients also have psychiatric problems of various degrees of severity.Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.Interview, Psychological: A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist.Age of Onset: The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.DibenzothiazepinesStress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)Schizophrenic Psychology: Study of mental processes and behavior of schizophrenics.Amygdala: Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.Conduct Disorder: A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)Child of Impaired Parents: Child with one or more parents afflicted by a physical or mental disorder.Personality Assessment: The determination and evaluation of personality attributes by interviews, observations, tests, or scales. Articles concerning personality measurement are considered to be within scope of this term.Expressed Emotion: Frequency and quality of negative emotions, e.g., anger or hostility, expressed by family members or significant others, that often lead to a high relapse rate, especially in schizophrenic patients. (APA, Thesaurus of Psychological Index Terms, 7th ed)Emotions: Those affective states which can be experienced and have arousing and motivational properties.Impulsive Behavior: An act performed without delay, reflection, voluntary direction or obvious control in response to a stimulus.Creativity: The ability to generate new ideas or images.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.Psychotherapy: A generic term for the treatment of mental illness or emotional disturbances primarily by verbal or nonverbal communication.Attention Deficit and Disruptive Behavior Disorders: Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors.Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Triazines: Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.Community Mental Health Centers: Facilities which administer the delivery of psychologic and psychiatric services to people living in a neighborhood or community.Functional Neuroimaging: Methods for visualizing REGIONAL BLOOD FLOW, metabolic, electrical, or other physiological activities in the CENTRAL NERVOUS SYSTEM using various imaging modalities.Personality Inventory: Check list, usually to be filled out by a person about himself, consisting of many statements about personal characteristics which the subject checks.Genome-Wide Association Study: An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers in unrelated patients with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition.Adolescent Psychiatry: The medical science that deals with the origin, diagnosis, prevention, and treatment of mental disorders in individuals 13-18 years.Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.Family Therapy: A form of group psychotherapy. It involves treatment of more than one member of the family simultaneously in the same session.Suicide: The act of killing oneself.Facial Expression: Observable changes of expression in the face in response to emotional stimuli.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Anticonvulsants: Drugs used to prevent SEIZURES or reduce their severity.Sleep Disorders: Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Child Psychiatry: The medical science that deals with the origin, diagnosis, prevention, and treatment of mental disorders in children.Endophenotypes: Measurable biological (physiological, biochemical, and anatomical features), behavioral (psychometric pattern) or cognitive markers that are found more often in individuals with a disease than in the general population. Because many endophenotypes are present before the disease onset and in individuals with heritable risk for disease such as unaffected family members, they can be used to help diagnose and search for causative genes.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Cognitive Therapy: A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Antisocial Personality Disorder: A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Brain Mapping: Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Affective Symptoms: Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.Carbamazepine: An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their three-dimensional structure is similar.Dysthymic Disorder: Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.Neuroimaging: Non-invasive methods of visualizing the CENTRAL NERVOUS SYSTEM, especially the brain, by various imaging modalities.Genetic Linkage: The co-inheritance of two or more non-allelic GENES due to their being located more or less closely on the same CHROMOSOME.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Tic Disorders: Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)Aspirations (Psychology): Strong desires to accomplish something. This usually pertains to greater values or high ideals.Family: A social group consisting of parents or parent substitutes and children.Limbic System: A set of forebrain structures common to all mammals that is defined functionally and anatomically. It is implicated in the higher integration of visceral, olfactory, and somatic information as well as homeostatic responses including fundamental survival behaviors (feeding, mating, emotion). For most authors, it includes the AMYGDALA; EPITHALAMUS; GYRUS CINGULI; hippocampal formation (see HIPPOCAMPUS); HYPOTHALAMUS; PARAHIPPOCAMPAL GYRUS; SEPTAL NUCLEI; anterior nuclear group of thalamus, and portions of the basal ganglia. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p744; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (September 2, 1998)).Psychotherapy, Group: A form of therapy in which two or more patients participate under the guidance of one or more psychotherapists for the purpose of treating emotional disturbances, social maladjustments, and psychotic states.Recurrence: The return of a sign, symptom, or disease after a remission.Cognition: Intellectual or mental process whereby an organism obtains knowledge.Psychometrics: Assessment of psychological variables by the application of mathematical procedures.Impulse Control Disorders: Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.Family Health: The health status of the family as a unit including the impact of the health of one member of the family on the family as a unit and on individual family members; also, the impact of family organization or disorganization on the health status of its members.Social Behavior Disorders: Behaviors which are at variance with the expected social norm and which affect other individuals.Executive Function: A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.Electroconvulsive Therapy: Electrically induced CONVULSIONS primarily used in the treatment of severe AFFECTIVE DISORDERS and SCHIZOPHRENIA.Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.Benzodiazepines: A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Attention: Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.Alcohol-Related Disorders: Disorders related to or resulting from abuse or mis-use of alcohol.Speech Disorders: Acquired or developmental conditions marked by an impaired ability to comprehend or generate spoken forms of language.Dominance, Cerebral: Dominance of one cerebral hemisphere over the other in cerebral functions.Checklist: Aid for consistent recording of data such as tasks completed and observations noted.Early Medical Intervention: Action taken to reduce susceptibility or exposure to health problems and to detect and treat disease in early stages.Psychopathology: The study of significant causes and processes in the development of mental illness.Haplotypes: The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.Demography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Somatoform Disorders: Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by a another medical condition, by the direct effects of a substance, or by another mental disorder. The symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)Pedigree: The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.Sensory Gating: The ability of the BRAIN to suppress neuronal responses to external sensory inputs, such as auditory and visual stimuli. Sensory filtering (or gating) allows humans to block out irrelevant, meaningless, or redundant stimuli.Frontal Lobe: The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.United StatesNeuropsychiatry: A subfield of psychiatry that emphasizes the somatic substructure on which mental operations and emotions are based, and the functional or organic disturbances of the central nervous system that give rise to, contribute to, or are associated with mental and emotional disorders. (From Campbell's Psychiatric Dictionary, 8th ed.)Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Neural Pathways: Neural tracts connecting one part of the nervous system with another.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Psychophysiologic Disorders: A group of disorders characterized by physical symptoms that are affected by emotional factors and involve a single organ system, usually under AUTONOMIC NERVOUS SYSTEM control. (American Psychiatric Glossary, 1988)Life Change Events: Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.Chronobiology Disorders: Disruptions of the rhythmic cycle of bodily functions or activities.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Anisotropy: A physical property showing different values in relation to the direction in or along which the measurement is made. The physical property may be with regard to thermal or electric conductivity or light refraction. In crystallography, it describes crystals whose index of refraction varies with the direction of the incident light. It is also called acolotropy and colotropy. The opposite of anisotropy is isotropy wherein the same values characterize the object when measured along axes in all directions.Nerve Fibers, Myelinated: A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
The social and economic effects of manic depressive illness and of its treatment in lithium clinics. (1/2554)Advising about the employment of those who have had manic depressive episodes requires Occupational Health Physicians to obtain, with consent, an objective account of previous episodes and to appreciate the enormous range of manic and depressive manifestations. Familiarity is needed with the likely effects of treatment of episodes and the benefits and problems of prophylaxis--not just in general but in individual cases, for example, where driving is required. This article summarizes research into the effects of lithium preparations on the course of the illness, thyroid and renal function and the risk of suicide. The author found that changing from treatment of episodes to continuous prophylaxis benefited employment and personal relationships without causing body weight problems. Many patients do well in life if supported by an experienced professional team, with 61% requiring no further admissions once on lithium, and with an 86% reduction in admissions achieved in our local clinic. (+info)
Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial. (2/2554)Total sleep deprivation (TSD) shows powerful but transient clinical effects in patients affected by bipolar depression. Pindolol blocks the serotonergic 5-HT1A autoreceptor, thus improving the antidepressant effect of selective serotonin reuptake inhibitors. We evaluated the interaction of TSD and pindolol in the treatment of acute episodes of bipolar depression. Forty bipolar depressed inpatients were randomized to receive pindolol 7.5 mg/day or placebo for nine days in combination with three consecutive TSD cycles. Pindolol significantly improved the antidepressant effect of TSD, and prevented the short-term relapse after treatment. The response rate (HDRS scores < 8) at the end of treatment was 15/20 for pindolol, and 3/20 for placebo. Coadministration of pindolol and TSD resulted in a complete response, which could be sustained for six months with lithium salts alone, in 65% of cases. This results suggest a major role for serotonergic transmission in the mechanism of action of TSD, and makes TSD treatment more effective in the treatment of bipolar depression. (+info)
A note on power approximations for the transmission/disequilibrium test. (3/2554)The transmission/disequilibrium test (TDT) is a popular method for detection of the genetic basis of a disease. Investigators planning such studies require computation of sample size and power, allowing for a general genetic model. Here, a rigorous method is presented for obtaining the power approximations of the TDT for samples consisting of families with either a single affected child or affected sib pairs. Power calculations based on simulation show that these approximations are quite precise. By this method, it is also shown that a previously published power approximation of the TDT is erroneous. (+info)
Acute barium intoxication following ingestion of ceramic glaze. (4/2554)A case of deliberate overdose of barium sulphide in a psychiatric setting is presented, with resulting flaccid paralysis, malignant arrhythmia, respiratory arrest and severe hypokalaemia, but ultimately with complete recovery. The degree of paralysis appears to be related directly to serum barium levels. The value of early haemodialysis, particularly with respiratory paralysis and hypokalaemia, is emphasised. (+info)
Pharmacogenetics of lithium response in bipolar disorder. (5/2554)Lithium is the first-line treatment for bipolar disorder. In the past, genetic studies have attempted to identify factors associated with positive treatment response or side effects. Several research groups have shown that familial factors, family history of primary bipolar disorder, and negative family history of schizophrenia in particular, correlate well with prophylactic lithium response. Conversely, studies of lithium responsive patients and their families can assist genetic research of bipolar disorder. Lithium responders appear to suffer from a form of bipolar disorder that is more genetically based and more homogeneous. In a series of family studies, the author and his colleagues have confirmed the differences in family histories of lithium responders and nonresponders and shown that the mode of inheritance in lithium responders is compatible with a major-gene model. Subsequently, they initiated an international collaborative study to map the gene(s) predisposing to the illness or treatment response, or both, using both linkage and association strategies. To date, a sample of 32 families, 138 unrelated patients and 163 control subjects has been studied. In these studies, they found support for the role of phospholipase C in lithium responsive bipolar disorder. (+info)
A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. (6/2554)Bipolar disorder is a severe mental illness characterized by mood swings of elation and depression. Family, twin, and adoption studies suggest a complex genetic etiology that may involve multiple susceptibility genes and an environmental component. To identify chromosomal loci contributing to vulnerability, we have conducted a genome-wide scan on approximately 396 individuals from 22 multiplex pedigrees by using 607 microsatellite markers. Multipoint nonparametric analysis detected the strongest evidence for linkage at 13q32 with a maximal logarithm of odds (lod) score of 3.5 (P = 0. 000028) under a phenotype model that included bipolar I, bipolar II with major depression, schizoaffective disorder, and recurrent unipolar disorder. Suggestive linkage was found on 1q31-q32 (lod = 2. 67; P = 0.00022) and 18p11.2 (lod = 2.32; P = 0.00054). Recent reports have linked schizophrenia to 13q32 and 18p11.2. Our genome scan identified other interesting regions, 7q31 (lod = 2.08; P = 0. 00099) and 22q11-q13 (lod = 2.1; P = 0.00094), and also confirmed reported linkages on 4p16, 12q23-q24, and 21q22. By comprehensive screening of the entire genome, we detected unreported loci for bipolar disorder, found support for proposed linkages, and gained evidence for the overlap of susceptibility regions for bipolar disorder and schizophrenia. (+info)
Plasma catecholamine metabolites as markers for psychosis and antipsychotic response in schizophrenia. (7/2554)The objective of this study was to determine the association between the patterns of change in the dopaminergic metabolite plasma homovanillic acid (HVA), the noradrenergic metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG), and psychosis following haloperidol withdrawal in schizophrenic patients. Weekly plasma measurements were obtained in 107 subjects with schizophrenia or schizoaffective disorder. Random regression was used to control for individual variance while modeling metabolite changes over time and relationships with psychosis. Changes in plasma MHPG were not significantly associated with relapse or psychosis, while increased plasma HVA was found to be associated with relapse. Psychosis was correlated negatively with plasma HVA levels. The current analysis, controlling for individual variance, indicates that there is evidence for pharmacological effects on plasma HVA, but not plasma MHPG. In addition, these metabolites do not appear to be direct markers of psychosis, but may be associated with a compensatory response by the system to return to the steady state. (+info)
Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18. (8/2554)Linkage disequilibrium (LD) analysis has been promoted as a method of mapping disease genes, particularly in isolated populations, but has not yet been used for genome-screening studies of complex disorders. We present results of a study to investigate the feasibility of LD methods for genome screening using a sample of individuals affected with severe bipolar mood disorder (BP-I), from an isolated population of the Costa Rican central valley. Forty-eight patients with BP-I were genotyped for markers spaced at approximately 6-cM intervals across chromosome 18. Chromosome 18 was chosen because a previous genome-screening linkage study of two Costa Rican families had suggested a BP-I locus on this chromosome. Results of the current study suggest that LD methods will be useful for mapping BP-I in a larger sample. The results also support previously reported possible localizations (obtained from a separate collection of patients) of BP-I-susceptibility genes at two distinct sites on this chromosome. Current limitations of LD screening for identifying loci for complex traits are discussed, and recommendations are made for future research with these methods. (+info)
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Symptoms of bipolar disorder are severe. They are different from the normal ups and downs that everyone goes through from time to time. Bipolar disorder symptoms can result in damaged relationships, poor job or school performance, and even suicide. But bipolar disorder can be treated, and people with this illness can lead full and productive lives.. Causes. Scientists are studying the possible causes of bipolar disorder. Most scientists agree that there is no single cause. Rather, many factors likely act together to produce the illness or increase risk.. Genetics. Bipolar disorder tends to run in families. Some research has suggested that people with certain genes are more likely to develop bipolar disorder than others. Children with a parent or sibling who has bipolar disorder are much more likely to develop the ...
Youths with major depression or bipolar disorder are at increased risk for CVD | Cardiovascular Business
After reviewing numerous clinical trials, the American Heart Association issued a scientific statement that mentioned children and adolescents with major depressive disorder or bipolar disorder are at increased risk for cardiovascular diseases later in life. The statement was published online in Circulation on Aug. 10.
Which pharmacologic treatment regimens are used in the treatment of bipolar affective disorder (manic-depressive illness)?
Appropriate medication depends on the stage of the bipolar disorder, or manic-depressive illness (MDI), the patient is experiencing. Thus, a number of drugs are indicated for an acute manic episode, p... more
Both Schizophrenia and bipolar disorders are problems in the thought processes of a human being. They are both very distressing conditions, with a degree of difference in symptoms and treatments. While it is very difficult for non medical people to differentiate between the two conditions, there are some differences that are evident to observers.. The most obvious differences between Schizophrenia and bipolar disorder are evident during the initial onset of the condition. Almost 30% of people who are diagnosed with bipolar disorder report that their condition started off with depression. A similar number of people also report that they had manic symptoms when their disease first started off. Only 9% of those surveyed remember psychotic experiences at the start of the disease ...
Care satisfaction, hope, and life functioning among adults with bipolar disorder: data from the first 1000 participants in the...
OBJECTIVE: The Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) is designed to evaluate the longitudinal outcome of patients with bipolar disorder. The STEP-BD disease-management model is built on evidence-based practices and a collaborative care approach designed to maximize specific and nonspecific treatment mechanisms. This prospective study examined the longitudinal relationships between patients satisfaction with care, levels of hope, and life functioning in the first 1000 patients to enter STEP-BD. METHODS: The study used scores from the Care Satisfaction Questionnaire, Beck Hopelessness Scale, Range of Impaired Functioning Tool, Young Mania Rating Scale, and Montgomery-Asberg Depression Rating Scale at 5 time points during a 1-year interval. Analyses tested mediational pathways between care satisfaction, hope, and life functioning, depression, and mania using mixed-effects (random and fixed) regression models. RESULTS: Increases in care satisfaction were associated with
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What is the role of lab studies in the evaluation of bipolar affective disorder (manic-depressive illness)?
A number of reasons exist for obtaining selected laboratory studies in patients with bipolar disorder, or manic-depressive illness (MDI). An extensive range of tests is indicated, because bipolar diso... more
OBJECTIVES: Conventional descriptions of bipolar disorder tend to treat the mixed state as something of an afterthought. There is no scale that specifically measures the phenomena of the mixed state. This study aimed to test a novel scale for mixed state in a clinical and community population of bipolar patients. METHODS: The scale included clinically relevant symptoms of both mania and depression in a bivariate scale. Recovered respondents were asked to recall their last manic episode. The scale allowed endorsement of one or more of the manic and depressive symptoms. Internal consistency analyses were carried out using Cronbach alpha. Factor analysis was carried out using a standard Principal Components Analysis followed by Varimax Rotation. A confirmatory factor analytic method was used to validate the scale structure in a representative clinical sample. RESULTS: The reliability analysis gave a Cronbach alpha value of 0.950, with a range of corrected-item-total-scale correlations from 0.546 (weight
Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses | International Journal...
We aimed to establish a bipolar disorder biobank to serve as a resource for clinical and biomarker studies of disease risk and treatment response. Here, we describe the aims, design, infrastructure, and research uses of the biobank, along with demographics and clinical features of the first participants enrolled. Patients were recruited for the Mayo Clinic Bipolar Biobank beginning in July 2009. The Structured Clinical Interview for DSM-IV was used to confirm bipolar diagnosis. The Bipolar Biobank Clinical Questionnaire and Participant Questionnaire were designed to collect detailed demographic and clinical data, including clinical course of illness measures that would delineate differential phenotypes for subsequent analyses. Blood specimens were obtained from participants, and various aliquots were stored for future research. As of September 2014, 1363 participants have been enrolled in the bipolar biobank. Among these first participants, 69.0 % had a diagnosis of bipolar disorder type I. The group
Bipolar disorder dates back to the time of Hippocrates (Healy). Hippocrates was the first to put mania and melancholia on our cultural radar (Healy). The symptoms he used to diagnose mania were that of nausea, shivering, insomnia, and lack of thirst (Healy). Until recently, bipolar II disorder has been virtually unknown and highly underdiagnosed. DSM-IV has separated bipolar disorders into two types, bipolar II and I. (Chengappa, Levine, Gershon, Kupfer). These two disorders may have differing genetic, biological, phenomenological attributes and course of illness characteristics (Chengappa, Levine, Gershon, Kupfer). There are many reasons for this. A lack of education regarding the disorder, misdiagnosis, and improper treatments are the number one reason for misdiagnosis. Physicians and mental health clinicians are just now learning the symptoms of bipolar II disorder. During a 2005 chart review, 37% of 90 bipolar II disorder patients were misdiagnosed as having unipolar depression. Bipolar II ...
Bipolar disorder not otherwise specified (BD-NOS) is a diagnosis for bipolar disorder (BD) when it does not fall within the other established sub-types. Bipolar disorder NOS is sometimes referred to as subthreshold bipolar disorder. BD-NOS is a mood disorder and one of three subtypes on the bipolar spectrum, which also includes bipolar I disorder and bipolar II disorder. BD-NOS was a classification in the DSM-IV and has since been changed to Bipolar "Other Specified" and "Unspecified" in the 2013 released DSM-5 (American Psychiatric Association, 2013). Bipolar disorder is difficult to diagnose. If a person displays some symptoms of bipolar disorder but not others, the clinician may diagnose bipolar NOS. The diagnosis of bipolar NOS is indicated when there is a rapid change (days) between manic and depressive symptoms and can also include recurring episodes of hypomania. Bipolar NOS may be diagnosed when it is difficult to tell whether bipolar is the primary disorder due to another general ...
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in a persons mood, energy, and ability to function. Different from the normal ups and downs that everyone goes through, the symptoms of bipolar disorder are severe. They can result in damaged relationships, poor job or school performance, and suicide. Bipolar disorder causes dramatic mood swings-from overly high and/or irritable to sad and hopeless, and then back again, often with periods of normal mood in between. Severe changes in energy and behavior go along with these changes in mood.. The precise neural basis of BD is unknown. In CIBSR, we are endeavoring to uncover some of the functional differences in brains of individuals with BD compared with normal individuals.. For ongoing research at Stanford click here.. For publications on this research click here.. ...
Does someone you care about have bipolar disorder? Symptoms of bipolar disorder - whether associated with a manic, depressive, or mixed state - can cause concern. With some basic information about bipolar disorder, knowledge of resources and interpersonal strategies, and compassion for yourself and others, you can provide meaningful support to a person with bipolar disorder. Keeping lines of communication open and planning ahead as much as possible help immeasurably in living with bipolar disorder.. Follow the buttons below for educational resources about bipolar disorder and the role of a caregiver to an adult living with bipolar disorder. We hope they help you and your family work together toward wellness.. ...
Bipolar II disorder: Find the most comprehensive real-world symptom and treatment data on bipolar II disorder at PatientsLikeMe. 8829 patients with bipolar II disorder experience irritability, fatigue, flight of ideas, grandiose thinking, and anxious mood and use Lamotrigine, Individual Therapy, Quetiapine, Lithium Carbonate, and Lurasidone to treat their bipolar II disorder and its symptoms.
Manic-depressive illnesses (Manic-depressive psychoses). These disorders are marked by severe mood swings and a tendency to remission and recurrence. Patients may be given this diagnosis in the absence of a previous history of affective psychosis if there is no obvious precipitating event. This disorder is divided into three major subtypes: manic type, depressed type, and circular type.. 296.1 Manic-depressive illness, manic type ((Manic-depressive psychosis, manic type)). This disorder consists exclusively of manic episodes. These episodes are characterized by excessive elation, irritability, talkativeness, flight of ideas, and accelerated speech and motor activity. Brief periods of depression sometimes occur, but they are never true depressive epi- sodes.. 296.2 Manic-depressive illness, depressed type ((Manic-depressive psychosis, depressed type)). This disorder consists exclusively of depressive episodes. These episodes are characterized by severely depressed mood and by mental and motor ...
Introduction. Bipolar disorder is a recurrent and chronic disorder with significant morbidity and mortality. It is characterized by a long-term episodic cyclical course of extreme fluctuations in mood that manifest as repeated manic, depressed, or mixed episodes with complete inter-episode recovery but high rates of chronicity that impact social and occupational development (Angst & Sellaro, 2000). According to the Systematic Treatment Enhancement Program for Bipolar Disorder, 5% of patients who fulfill the criteria for recovery suffer relapses each month (Baldassano, 2006). Although some rare individuals may experience only a single episode of mania and depression in their lifetime, ,95% of people with bipolar disorder have recurrent episodes of mania and depression throughout their lives (Goodwin & Jamison, 1990).. Bipolar disorder is a common disorder that affects 1% of the population. This prevalence may increase according to the diagnostic criteria used in each study (Judd & Akiskal, 2003). ...
Bipolar affective disorder is a severe, heritable condition affecting about one percent of. the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute to the risk of bipolar disorder. Individuals diagnosed with bipolar disorder are studied, along with their relatives. Phenotypic information obtained from clinical interviews and family history is correlated with genotypic information obtained from genetic marker and sequencing methods. The goal is to identify genes involved in bipolar disorder and related conditions so that better methods of diagnosis, treatment, and prevention can be developed. ...
Bipolar affective disorder is a severe, heritable condition affecting about one percent of. the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute to the risk of bipolar disorder. Individuals diagnosed with bipolar disorder are studied, along with their relatives. Phenotypic information obtained from clinical interviews and family history is correlated with genotypic information obtained from genetic marker and sequencing methods. The goal is to identify genes involved in bipolar disorder and related conditions so that better methods of diagnosis, treatment, and prevention can be developed. ...
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in a persons mood, energy, and ability to function.. The mood episodes associated with the disorder persist from days to weeks or longer, and can be dramatic, with periods of being overly high and/or irritable to periods of persistent sadness and hopelessness.. Severe changes in behavior go along with the mood changes. These periods of highs and lows, called episodes of mania and depression, can be distinct episodes often recurring over time, or they may occur together in a so-called mixed state. Often people with bipolar disorder experience periods of normal mood in between mood episodes.. A manic episode is diagnosed if an elevated mood occurs with three or more primary symptoms most of the day, nearly every day, for at least one week. With an irritable mood, four additional symptoms must be present for a diagnosis.. Signs and symptoms of a manic episode can include the following:. ...
FDA Approves Extended-Release Aripiprazole Injected Monthly to Prevent Manic and Mixed Episodes in Bipolar I : Bipolar Network...
In 2017 the US Food and Drug Administration approved a monthly injectable form of the atypical antipsychotic drug aripiprazole, Abilify Maintena, for the prevention of manic and mixed episodes in bipolar I disorder. The intramuscular injections are available for monotherapy in preparations of 300 mg or 400 mg. Maintena did not prevent depressive episodes.. Maintena is already FDA-approved for the treatment of schizophrenia and Tourettes syndrome in adults.. The approval for bipolar I disorder follows a 52-week phase 3, double-blind, placebo-controlled randomized trial. Participants were experiencing a manic episode during screening for the study, met the criteria for bipolar I disorder, and had had at least one prior manic or mixed episode severe enough to require treatment.. Compared to placebo, Maintena in once-a-month injections delayed the recurrence of any mood episode following the initial manic episode at screening. When the researchers separated their analysis based on type of episode, ...
Omega-3 Fatty Acids Improve Mood and Limbic Hyperactivity in Youth with Bipolar Depression : Bipolar Network News
Children who have a parent with bipolar disorder are at risk for bipolar illness, but it may first present as depression. Treating these children with antidepressants has the risk of bringing on manic episodes. Researchers are looking for treatment options for youth at risk for bipolar disorder.. Robert McNamara and colleagues found that 12 weeks of omega-3 fatty acids (2,100 mg/day) significantly improved response rates in medication-free youth ages 9-20 years compared to placebo (64% versus 36%). Omega-3 fatty acids but not placebo also reduced the activation of limbic structures in the brain (the left parahippocampal gyrus) in response to emotional stimuli.. Editors Note: These data add to the literature on the positive effects of 1-2 grams of omega-3 fatty acids in depression. Given the safety of omega-3 fatty acids and the ambiguous effects of antidepressants in bipolar depression, omega-3 fatty acids would appear to a good alternative, especially since the FDA-approved atypical ...
Autonomic nervous system arousal and cognitive functioning in bipolar disorder - Levy - 2012 - Bipolar Disorders - Wiley Online...
Levy B. Autonomic nervous system arousal and cognitive functioning in bipolar disorder. Bipolar Disord 2012: 00: 000-000. © 2012 John Wiley & Sons A/S.Published by Blackwell Publishing Ltd.. Objective: Previous theories about the etiology of cognitive dysfunction in bipolar disorder (BD) emphasized trait factors such as neurological impairment. State factors, other than mood symptoms, that may exacerbate functional deficits have not yet been considered. The purpose of this study was to examine autonomic nervous system (ANS) arousal following cognitive challenge. The study compared patients with BD and healthy controls (HC) in physiological measures and neuropsychological test scores.. Methods: Thirty euthymic patients with BD and 22 HC completed the study. Participants completed mood [Beck Depression Inventory-II (BDI-II) and Young Mania Rating Scale (YMRS)], anxiety (State-Trait Anxiety Inventory), and substance abuse (Drug Abuse Screening Test-20 item and Alcohol Use Disorders Identification ...
The anesthetic ketamine (sometimes illicitly-used as a recreational drug) produced rapid alleviation of severe depression in patients with treatment-resistant bipolar illness in a small clinic trial.
Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis | The British...
The results of the meta-analysis suggest that individuals with bipolar disorder are 2.6 times more likely to experience childhood adversity when compared with a non-clinical control group. This effect did not appear to be the result of study design or bias, and remained robust and significant even after controlling for hypothetically missing studies. The findings should be interpreted in the context of relatively few longitudinal studies and none with a prospective cohort design, limiting the ability to make causal inferences. Nevertheless, there appears to be a strong and significant association between childhood adversity and bipolar disorder.. We found some variances in this association when specific types of exposure were analysed separately. Emotional abuse was four times more likely to have occurred in bipolar disorder groups than in healthy controls, an effect seemingly larger than for other types of adversity. This is in contrast to a recent meta-analysis that observed roughly equivalent ...
Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional...
In the present study we leveraged the power of GWAS data from two independent schizophrenia and bipolar disorder samples, and demonstrate how GWAS from associated psychiatric disorders can improve discovery of novel susceptibility loci. Using standard GWAS analytical methods, we identified only one significant locus. By applying traditional FDR methods in the separate GWAS samples, we found an additional 6 loci (2 in bipolar disorder, 4 in schizophrenia). Combining the independent schizophrenia and bipolar disorder GWAS samples, we identified a total of 58 loci in schizophrenia and 35 in bipolar disorders, with conditional FDR,0.05 as a threshold. Nine of the current loci have been identified earlier in larger samples using standard GWAS analytical methods (7 in schizophrenia, 5 in bipolar disorder, and 3 in combined samples), while 10 other loci have been reported to show borderline association with bipolar disorder or schizophrenia (Table S1). These results demonstrate the feasibility of using ...
Manifest Psychopathology and Urine Biochemical Measures (Multivariate Analysis in Manic-Depressive Illness) :: Special Interest...
Post a Comment for Manifest Psychopathology and Urine Biochemical Measures (Multivariate Analysis in Manic-Depressive Illness) ...
Serial analysis of gene expression in the frontal cortex of patients with bipolar disorder | The British Journal of Psychiatry
The specificities of the RNA transcripts which we found to be present at elevated levels in the frontal cortex of individuals with bipolar disorder are of interest in terms of possible pathophysiological mechanisms of this disease. Previous research data suggest that serotonin plays a central role in neural communication within the central nervous system. Furthermore, levels of serotonin can affect mood, appetite, sleep, pain perception and several aspects of human behaviour (Kanner & Schuldiner, 1987; Amara & Kuhar, 1993; Young et al, 1996). The emerging understanding of the biological properties of serotonin has led to considerable interest in the possible role of the serotonin transporter gene in determining susceptibility to bipolar disorder. While mutations in the coding region have not been found, several studies have documented an association between the variable number of tandem repeats in the transcriptional control region of the gene and the occurrence of bipolar disorder (Battersby et ...
Although the concept of mixed states had been well accepted by many of his contemporaries, including Bleger ("Outline of Psychiatry", 1924), not all of them recognized the concept at the time the premises of his formulas were published. "Breaking" the manic-depressive illness into the affective, intellectual and cognitive spheres seemed unacceptable to Jaspers. Jaspers stated: "The procedure is ambiguous since the meaningful connections are approached as objective components of psychic life (capable of being separated and mechanically joined)".13 Schneider14 was even more emphatic: "We no longer believe in mixed states. ( ) What may give the appearance of mixed states consists of the change from one state to another, in a way that we may simply call them cyclothymia" ("cyclothymia" was the term used by Schneider for the manic-depressive illness as a whole). On the other hand, Leonhard,15 a disciple of Kleist, not only accepted but emphasized the importance of the "mixed" characteristics in the ...
Bipolar disorder - What are the symptoms of bipolar disorder like? Varied. The symptoms vary depending on the type of bipolar disorder. There is bipolar i, bipolar ii, cyclothymia and bipolar disorder nos. Manic symptoms can include a marked increase in energy and decreased need for sleep, racing thought, rapid speech, euphoric mood, hypersexual, hyper religious, grandiose delusion, etc. Depression in bipolar disorder often looks like unipolar depression.
BACKGROUND: Bipolar disorder is a common recurrent illness with high levels of chronicity. Treatment resistance persists despite the use of established medications, such as lithium and valproate. New medications are required for the treatment of refractory cases. Retrospective and open-label trials have suggested that the anticonvulsant topiramate may be efficacious in bipolar disorder. There is a need to clarify the evidence available in the form of randomised controlled trials for its use in bipolar disorder. OBJECTIVES: To review the evidence for the efficacy and acceptability of topiramate in the treatment of acute mood episodes in bipolar disorder. SEARCH STRATEGY: The Cochrane Collaboration Depression, Anxiety and Neurosis (CCDAN) group search strategy was used. The following databases were searched:The Cochrane Collaboration Depression, Anxiety and Neurosis Controlled Trials Register (CCDANCTR), September 2003;The Cochrane Controlled Clinical Trials Register (CCCTR), September 2003;EMBASE (1980
Association of family history of bipolar disorder with risk of violence in inpatient mania: a cohort study
Background. Evidence suggests that a positive family history of bipolar affective disorder is associated with response to lithium and the course of the illness, in people suffering from this disorder. This may indicate a subgroup of patients with unique characteristics and treatment responses.. Aims. To explore associations between a positive family history of bipolar disorder and the risk of violence, in patients hospitalized for treatment of mania.. Methods. Adults receiving inpatient treatment for a manic relapse of bipolar affective disorder, at two tertiary care hospitals in Kandy, Sri Lanka were studied as a cohort. For each participant with a positive family history of bipolar disorder, an age and gender matched adult, also suffering from a manic relapse of bipolar affective disorder but without a family history, was included as a control. A second researcher, who was blind to the participants family history, assessed the risk of violence among all participants, at baseline, and at ...
Both schizophrenia and bipolar disorder are characterized as psychiatric disorders in the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5). Schizophrenia is a primary psychotic disorder, and bipolar disorder is a primary mood disorder but can also involve psychosis. However, because of some similar symptoms, differentiating between the two can sometimes be difficult; indeed, there is an intermediate diagnosis schizoaffective disorder. While reported and observed symptoms are a main way to diagnose either disorder, recent research studies are allowing psychiatrists to use magnetic resonance imaging (MRI) scans to try to find better, definite markers. Through MRIs, the psychiatrists can see specific structural differences in the brain that psychiatric medicines have made in the patient. These differences include volume of gray matter, neuropathological size differences variations, and cortical thickness, which then associated with cognitive differences on tests. These ...
J Clin Psychiatry/Levetiracetam in the Management of Bipolar Depression: A Randomized, Double-Blind, Placebo-Controlled Trial
Objective: To study the efficacy of adjunctive levetiracetam therapy compared with placebo in the treatment of subjects with depression with bipolar disorder.. Method: This double-blind, placebo-controlled clinical trial randomly assigned outpatients with bipolar disorder type I and type II who were experiencing a major depressive episode (Structured Clinical Interview for DSM-IV Axis I Disorders-Clinician Version criteria) to treatment with either placebo or adjunctive levetiracetam (up to 2,500 mg/d flexibly dosed) for 6 weeks. The subjects were recruited from October 2005 to June 2008. The primary efficacy measure was mean change from baseline to week 6 in the Hamilton Depression Rating Scale (21-item). Secondary efficacy assessments included the Montgomery-Åsberg Depression Rating Scale, the Beck Depression Inventory, the Clinical Global Impressions-Bipolar Version scale, the Hamilton Anxiety Rating Scale, and the Young Mania Rating Scale.. Results: Of 42 subjects randomly assigned to ...
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks.. There are four basic types of bipolar disorder; all of them involve clear changes in mood, energy, and activity levels. These moods range from periods of extremely "up," elated, and energized behavior (known as manic episodes) to very sad, "down," or hopeless periods (known as depressive episodes). Less severe manic periods are known as hypomanic episodes.. ...
Comorbidity is the rule, not the exception, in bipolar disorder. The most common mental disorders that co-occur with bipolar disorder in community studies include anxiety, substance use, and conduct disorders. Disorders of eating, sexual behavior, attention-deficit/hyperactivity, and impulse control, as well as autism spectrum disorders and Tourettes disorder, co-occur with bipolar disorder in clinical samples. The most common general medical comorbidities are migraine, thyroid illness, obesity, type II diabetes, and cardiovascular disease. Bipolarity is a marker for comorbidity, and comorbid disorders, especially multiple conditions occurring when a patient is young, may be a marker for bipolarity. Relatively few controlled clinical studies have examined the treatment of bipolar disorder in the context of comorbid conditions (i.e., complicated or comorbid bipolar disorder). However, the first step in treating any type of complicated bipolar disorder-stabilizing a patients mood-may be ...
Bipolar Disorder Therapeutic Industry Pipeline Review H2 2016, Drug Profile and Major Key Players Analysis | Business
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. Bipolar Disorder Pipeline Review, H2 2016, latest research study provides in depth analysis on Cellular Tumor Antigen P53 (Tumor Suppressor P53 or Antigen NY-CO-13) targeted pipeline therapeutics.. Bipolar Disorder therapeutics industry report provides comprehensive information on the therapeutics under development for Bipolar Disorder, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Bipolar Disorder and features dormant and discontinued projects.. Bipolar disorder was formerly called manic depression. It is a form of major affective disorder, or mood disorder, ...
Hirschfeld RM, Lewis L, Vornik LA. Perceptions and impact of bipolar disorder: how far have we really come? Results of the national depressive and manic-depressive association 2000 survey of individuals with bipolar disorder. J Clin Psychiatry. 2003 Feb;64(2):161-74. PubMed PMID: 12633125.. McElroy SL, Altshuler LL, Suppes T, Keck PE Jr, Frye MA, Denicoff KD, Nolen WA, Kupka RW, Leverich GS, Rochussen JR, Rush AJ, Post RM. Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry. 2001 Mar;158(3):420-6. PubMed PMID: 11229983.. Simon NM, Otto MW, Weiss RD, Bauer MS, Miyahara S, Wisniewski SR, Thase ME, Kogan J, Frank E, Nierenberg AA, Calabrese JR, Sachs GS, Pollack MH; STEP-BD Investigators. Pharmacotherapy for bipolar disorder and comorbid conditions: baseline data from STEP-BD. J Clin Psychopharmacol. 2004 Oct;24(5):512-20. PubMed PMID: 15349007.. ...
Bipolar Affective Disorder Medication: Anxiolytics, Benzodiazepines, Mood stabilizers, Anticonvulsants, Antipsychotics, 2nd...
Bipolar affective disorder, or manic-depressive illness (MDI), is a common, severe, and persistent mental illness. This condition is a serious lifelong struggle and challenge.
This study aims to characterize the atypical developmental trajectory of functional brain circuitry and neurocognitive function in adolescent bipolar disorder (...
A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder | USC Research Bank - University...
Bipolar disorder is regarded as a disorder of mood and initial studies have focused on structural abnormalities in limbic networks, known to subserve mood. More recently, functional imaging studies allude to affect processing deficits, which may involve frontostriatal networks. This study sought to explore disturbances in networks involved in the processing of negative affect in euthymic bipolar patients. We used simultaneous functional magnetic resonance imaging and galvanic skin responsivity to explore disturbances in these networks. When processing negative affect, controls recruited a distributed subcortical-prefrontal network. In contrast, patients could only activate a subcortical network that included the amygdala and hippocampus. This study provides evidence for a disconnection in the transfer of information within frontostriatal networks in bipolar disorder. © 2007 Lippincott Williams & Wilkins, Inc.
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and...
Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of approximately 80% indicating a substantial genetic component. Population genetics and genome-wide association studies suggest an overlap of genetic risk factors between these illnesses but it is unclear how this genetic component is divided between common gene polymorphisms, rare genomic copy number variants, and rare gene sequence mutations. We report evidence that the lipid transporter gene ABCA13 is a susceptibility factor for both schizophrenia and bipolar disorder. After the initial discovery of its disruption by a chromosome abnormality in a person with schizophrenia, we resequenced ABCA13 exons in 100 cases with schizophrenia and 100 controls. Multiple rare coding variants were identified including one nonsense and nine missense mutations and compound heterozygosity/homozygosity in six cases. Variants were genotyped in additional schizophrenia, bipolar, depression (n , ...
There is strong evidence that genetic factors make substantial contributions to the etiology of autism, schizophrenia and bipolar disorders, with heritability estimates being at least 80% for each. These illnesses have complex inheritance, with multiple genetic and environmental factors influencing disease risk; however, in psychiatry, complex genetics is further compounded by phenotypic complexity. Autism, schizophrenia and bipolar disorder are effectively syndromic constellations of symptoms that define groups of patients with broadly similar outcomes and responses to treatment. As such the diagnostic categories are likely to be heterogeneous and the boundaries between them somewhat arbitrary. Recent applications of whole-genome technologies have discovered rare copy number variants and common single-nucleotide polymorphisms that are associated with risk of developing these disorders. Furthermore, these studies have shown an overlap between the genetic loci and even alleles that predispose to the
Many people with undiagnosed bipolar disorder may end up in the hospital during a manic episode. Once the patient has stabilized, they may be sent to a psychologist for a diagnosis. The therapist will ask about symptoms the person has suffered, including how long symptoms last. In some cases, a person with bipolar disorder is initially misdiagnosed with depression or anxiety, which are common mood disorders, and begins to receive treatment for those issues. If treatment does not work or it triggers a manic episode, then the therapist will try a different approach. ...
People with bipolar disorder are sometimes treated with antiepileptic drugs but there have been worries that these can increase peoples suicide risk. Researchers from the University of Illinois at Chicago studied 47,918 people with bipolar disorder, 13,385 of whom were taking antiepileptics. They found that those taking the antiepileptic drugs had similar rates of suicide attempts as those taking lithium or those people who were taking no medication at all. In fact after people started taking the antiepileptic drugs they had a significantly lower rate of suicide attempts than before they had started taking them. Relative to taking no medication at all taking antiepileptic medication led to a fivefold decrease in risk ...
... s are one of several medical conditions called depressive disorders that affect the way a persons brain functions. Find out more about bipolar disorder.
... s are one of several medical conditions called depressive disorders that affect the way a persons brain functions. Find out more about bipolar disorder.
In the bipolar disorder story success. The fees charged vary depending on the market achieved FDA approval for adult Attention Deficit are often uncomfortable in new or unfamiliar environments since they may seem normal when they talk and understand how to accept and live successfully with bipolar disorder need therapists who help them exercise cognitive control of emotions. Interpersonal therapy focuses on developing the bipolar disorder story success and resolve interpersonal conflicts, which frequently accompany bipolar disorder. Both of these conditions, it is probably determined by multiple factors. Family and adoption studies have been conducted to pin down its cause, but up to the bipolar disorder story success a change in fashion, and constantly checking their weight. Some social changes of a series of stressful events in a major cause of eating disorders. Singer Karen Carpenter was struggling with anorexia may also be mental retardation if it is unclear which came first, the bipolar ...
Bipolar affective disorder, or manic-depressive illness (MDI), is a common, severe, and persistent mental illness. This condition is a serious lifelong struggle and challenge.
Wednesday, 18 July 2012 20:09 A Solution for Treating Bipolar Disorder. The Merck Manual describes bipolar disorder as "a condition in which periods of depression alternate with periods of mania or lesser degrees of excitement." 1 Historically known as manic-depressive disorder, this psychiatric condition is typically defined by the presence of abnormally elevated energy levels affecting mood and awareness, with or without states of depression. Manic states are often accompanied by psychotic symptoms such as delusions and hallucinations.. Allopathic medicines solution generally involves one or more pharmaceuticals for a lifetime; it never offers a cure but rather, management of erratic behavior via medications that often need to be changed from time to time. Quite commonly, those suffering from bipolar disorder are very bright, creative and loving individuals. Sadly, when brain chemistry goes out of balance, the sufferer most often deals with chaos involving hallucinations, as well as extreme ...
Use of antipsychotic drugs and mood stabilizers in women of childbearing age with schizophrenia and bipolar disorder:...
Aims. To determine the prevalence of women of childbearing age with schizophrenia and bipolar disorder exposed to antipsychotic (AP) drugs and mood stabilizers (MS) in Lombardy, a European region of 10 million inhabitants and 1 752 285 women of childbearing age. Methods. The data concerning psychiatric care, drug treatments and pregnancy outcomes were retrieved from local administrative databases during a 12-month census period. Results. During a 12-month census period, 2893 women of childbearing age with schizophrenia (74.8% of all women of childbearing age with schizophrenia) and 918 with bipolar disorder (80.1% of all women of childbearing age with bipolar disorder) were exposed to AP drugs or MS, yielding a prevalence of exposure for women with schizophrenia of 1.65 (95% confidence interval (CI) 1.59-1.71) per 1000 female inhabitants, and for women with bipolar disorder of 0.52 (95% CI 0.49-0.55) per 1000 female inhabitants. Persistent exposure to potentially teratogenic medications accounted for
Professor Hugh Gurling, UCL Department of Mental Health Sciences, says: "The next step is to determine the role of the Slynar gene in the brain and how abnormalities in this gene may cause bipolar disorder. Using techniques such as animal models will help us to fully understand the mechanisms behind this gene and explore how we might be able to intervene in these mechanisms, to help people with the disorder. "We hope our discovery will eventually lead to new treatments for depression and bipolar disorder, including possible preventive strategies, for example with drugs or even through nutritional intervention." Around one in every 200 people in the UK develops bipolar and other related mood disorders. Signs of depression include losing weight, feeling totally negative about oneself, feel hopeless about the future and sometimes ending up in a depressive stupor in bed, unable to move, eat, drink or talk. People with bipolar disorder may also experience extreme mood highs, overactivity, increased ...
A transcript map encompassing a susceptibility locus for bipolar affective disorder on chromosome 4q35 | Garvan Institute of...
Bipolar affective disorder is one of the most common mental illnesses with a population prevalence of approximately 1%. The disorder is genetically complex, with an increasing number of loci being implicated through genetic linkage studies. However, the specific genetic variations and molecules involved in bipolar susceptibility and pathogenesis are yet to be identified. Genetic linkage analysis has identified a bipolar disorder susceptibility locus on chromosome 4q35, and the interval harbouring this susceptibility gene has been narrowed to a size that is amenable to positional cloning. We have used the resources of the Human Genome Project (HGP) and Celera Genomics to identify overlapping sequenced BAC clones and sequence contigs that represent the region implicated by linkage analysis. A combination of bioinformatic tools and laboratory techniques have been applied to annotate this DNA sequence data and establish a comprehensive transcript map that spans approximately 5.5 Mb. This map encompasses the
Bipolar Disorder Treatment Wyandanch NY - Wyandanch NY, Bipolar Disorder Treatment, Wyandanch NY bipolar disease, Wyandanch NY...
Being bipolar and living with the illness means that you should have a bipolar disorder treatment plan in place. This usually begins to be formed from the time that a diagnosis of bipolar disorder is made. Often the bipolar disorder treatment is split into two types - one for treating manic episodes and one for treating depressive episodes.
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In this show Michael Pipich, MS,LMFT, therapist and national speaker on Bipolar Disorder, draws upon his new book, Owning Bipolar: How Patients and Families Can take Control of Bipolar Disorder to make owning and properly treating Bipolar Disorder a reality. | Owning Bipolar Disorder - A Guide for Patients and Family Thursday, October 4, 2018 on Psych Up Live | VoiceAmerica - The Leader in Internet Media
Transcript Bipolar illnesses comprise of depressive episodes, as well as, distinct manic episodes. And briefly in a manic episode it can be thought short hand
American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 147B:914 -917 (2008) Association of DAO and G72(DAOA)/G30 Genes With Bipolar Affective Disorder Diana Prata,1,2 Gerome Breen,1,2 Sarah Osborne,2 Janet Munro,2 David St. Clair,3 and David Collier1,2* 1 Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK Division of Psychological Medicine, Institute of Psychiatry, London, UK 3 Department of Mental Health, University of Aberdeen, Aberdeen, UK 2 There is growing evidence of partial aetiological overlap between schizophrenia and bipolar disorder (BP) from linkage analysis, genetic epidemiology and molecular genetics studies. In the present study we investigated whether individual polymorphisms or haplotypes of the DAO and G72(DAOA)/G30 genes, which have been previously implicated in schizophrenia, are also associated with bipolar disorder. For each gene, we genotyped 213 cases and 197 controls for SNPs previously associated with schizophrenia: ...
The offspring of individuals with bipolar disorder are at increased risk of mental illness, but our tools to predict which of these genetically at-risk young people will eventually develop disorder are very imprecise. Longitudinal studies that ascertain at-risk participants and monitor them prospectively are an effective approach for identifying early clinical and biological markers of future illness. In collaboration with the Black Dog Institute plus groups from four independent US-based sites, including: Johns Hopkins University; University of Michigan; Washington University in St. Louis; Indiana University; we are following a cohort of young kids and siblings of bipolar disorder patients with annual clinical, neurocognitive and lifestyle assessments; plus bi-annual brain imaging of the Australian participants. We are assessing the genetic load of multiple risk variants across the genome in these at-risk individuals to determine if we can use genetic information to help predict which ...
Bipolar Disorder is a common and complex mental disorder with a prevalence of 1-2 % and accounts as one of the most important causes of disability at age 15-44 years worldwide. The disorder is a long-term heterogeneous illness with a continued need for treatment and naturalistic follow-up studies suggest that the progressive development of bipolar disorder is not prevented with the present treatment options. Electronic versions of self-monitoring tools and symptom registration using computers, personal digital assistants (PDAs), text messages, and web interfaces have been described in the literature and a number of commercial Smartphone applications (e.g. Optimism, MoodRythm, iMoodJournal, eMoods Bipolar Disorder Tracker, Bipolar Bear, Moody Me etc.) for patients with bipolar disorder are available on the market.. ...
(Medical Xpress)-Adolescents with bipolar disorder are more likely to develop substance use disorders than adolescents without psychiatric disorders. Now, researchers at the University of Cincinnati (UC) have identified specific risk factors underlying this relationship.
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Coming out of the Mental Illness Closet: I have Bipolar Disorder Type 1 - Mental Health Nonprofit | This Is My Brave, Inc.
I am writing this because after being diagnosed with bipolar disorder, although I was surrounded by love and support from my family and friends, I never felt more alone.
How does the bipolar disorder affects girls. Teenagers with suicidal depression for several days before menstrual period. How to treat bipolar illness in girls and how it affects their sexual feelings.
Comorbidity of bipolar disorder with alcohol and drug abuse, leading to suicidal behavior - Internet and Psychiatry
Suicidal Behavior in Alcohol and Drug Abuse and Dependence. Hauppauge, New York: Nova Science Publishers, 2010, 540 pages. Background. Bipolar disorder is a frequent and chronic affective illness associated with significant global dysfunction and suicidal behavior. Bipolar patients frequently have other Axis I psychiatric disorders such as substance abuse or dependence affecting up to 60% of these individuals. Substance use disorders can independently lead to risk-taking behaviors and suicidality. Therefore, we gathered data about bipolar disorder and substance use disorders as single and as combined factors leading to suicidal behavior. We also discussed some neurobiological findings related to this comorbidity.. Methods. We reviewed the Medline database in search for studies published in English, Spanish or Portuguese until June 1st 2009, containing the following keywords: "bipolar disorder", "suicidal behavior", "suicide", "substance use disorders", "alcohol", "drugs", "cocaine", "cannabis", ...
It has been conventional for psychiatric research, including the search for predisposing genes, to proceed under the assumption that schizophrenia and bipolar disorder are separate disease entities with different underlying etiologies. These represent Emil Kraepelins traditional dichotomous classification of the so-called "functional" psychoses and form the basis of modern diagnostic practice. However, findings emerging from many fields of psychiatric research do not fit well with this model. In particular, the pattern of findings emerging from genetic studies shows increasing evidence for an overlap in genetic susceptibility across the traditional classification categories-including association findings at DAOA(G72), DTNBP1 (dysbindin), COMT, BDNF, DISC1, and NRG1. The emerging evidence suggests the possibility of relatively specific relationships between genotype and psychopathology. For example, DISC1 and NRG1 may confer susceptibility to a form of illness with mixed features of ...
In recent years the diagnostic status of people with depression who become hypomanic during antidepressant therapy has been a contentious issue. Many psychiatrists believe that in patients with no previous history of hypomania, brief periods of hypomania occurring within weeks of starting antidepressants should not necessarily lead to a diagnosis of bipolar illness. In DSM-III-R, antidepressant-associated hypomania was considered part of the bipolar spectrum, whereas in DSM-IV it is categorised as a substance-induced mood disorder. However, a consensus is re-emerging that people with depression who experience antidepressant-associated hypomania are truly bipolar.. This is a difficult area because many of the original descriptions of antidepressant-induced hypomania did not distinguish between patients with pre-existing diagnoses of unipolar or bipolar disorder. In addition, most treatment trials of antidepressants for depression do not systematically assess patients for hypomanic symptoms ...
Interpersonal and Social Rhythm Therapy (IPSRT) is an empirically-supported individual psychotherapy for the treatment of adults with bipolar disorder. This innovative approach to the management of bipolar disorder was developed by Ellen Frank and colleagues at the University of Pittsburgh and has now been shown to be efficacious in preventing relapse of mania and depression and in treating acute episodes of bipolar depression when used in combination with pharmacotherapy. Open studies suggest that it has utility as a monotherapy for adults with bipolar II disorder and for adolescents with bipolar I or II illness. IPSRT combines a behavioral approach to increasing the regularity of daily routines (social rhythms) with an interpersonal approach to coping with the stresses of the bipolar illness itself, as well as with common interpersonal stressors and social role problems. This approach has now been expanded to include group models for inpatient, intensive outpatient (day-hospital) and standard ...
Addiction and Bipolar Disorder are closely linked. Call 866.267.3273 to learn more about dual diagnosis treatment at Lakeview Health.
Google Hangout: Is lithium really the best drug for long term treatment in bipolar disorder? - Evidence-Based Mental Health Blog
The original paper: Miura et al. Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: A systematic review and network meta-analysis. Lancet Psych 2014;1:351-359. The EBMH commentary by Charles Bowden will be freely available as soon as it is published online first. (We will post the link soon.). In many clinical guidelines, lithium is considered the established standard in the long-term treatment of bipolar disorder, but several new drugs have been assessed for this indication. In a recent systematic review and network meta-analysis published in the Lancet Psychiatry in 2014, Miura and colleagues investigated the comparative efficacy and tolerability of available pharmacological treatment strategies for bipolar disorder. They searched Embase, Medline, PreMedline, PsycINFO, and the Cochrane Central Register of Controlled Trials for randomised controlled trials (until June 2013), that compared active treatments for bipolar disorder ...
Researchers Refine DNA Testing For Predisposition to Bipolar Disorder - Healthcanal.com : Healthcanal.com
This is an important advance in the development of a prototype for lab tests for bipolar disorder, and can serve as a model for developing tests in other complex disorders," said lead author Alexander B. Niculescu III, M.D., Ph.D., associate professor of psychiatry and medical neuroscience at the IU School of Medicine and director of INBRAIN at the IU Institute of Psychiatric Research.. Dr. Niculescu and colleagues used two different populations from large scale genetic studies and compared those individuals genes to a small panel of 56 genes implicated in bipolar disorder by their work, to predict who has a predisposition to the disease.. The analysis resulted in a genetic risk prediction score that indicates high or low potential for developing bipolar disorder. "The coupling of a high score with certain environmental factors may be a predictor, not a certainty, that the individual will develop bipolar disorder" said Dr. Niculescu, who also is a staff psychiatrist at the Indianapolis ...
Bipolar disorder (previously known as manic depression) is a psychiatric diagnostic category describing a class of mood disorders in which the person experiences clinical depression and/or mania, hypomania, and/or mixed states. The disorder can cause great distress among those afflicted and those living with them. Left untreated, bipolar disorder can be a disabling condition, with a high risk of death through suicide." "The difference between bipolar disorder and unipolar disorder (also called major depression) is that bipolar disorder involves both elevated and depressive mood states. The duration and intensity of mood states varies widely among people with BiPolar disorder. Fluctuating from one mood state to the next is called "cycling". Mood swings can cause impairment or improved functioning depending on their direction (up or down) and severity (mild to severe). There can be changes in ones energy level, sleep pattern, activity level, social rhythms and cognitive functioning. Some people ...
3 No exact cause has been found for bipolar disorder. It does run in families, so doctors say there is a genetic predisposition for it. In over eighty percent of those who have bipolar disorder, there is a family history of depression. Just because someone in the family has bipolar disorder doesnt mean another person in the family has to get it. Researchers believe that something biological or environmental combined with genetics triggers the disorder. So, for example, if a person has a genetic predisposition for it and that person experiences something stressful, bipolar disorder is more likely to occur ...
WPICs pediatric bipolar disorder clinic is featured in the New York Times Magazine Sept. 14 cover story on bipolar disorder in children.
Bipolar Disorder, Read about Bipolar Disorder symptoms, causes, diagnosis, and treatment. Also read Bipolar Disorder articles about how to live with Bipolar Disorder, and more.
Bipolar Disorder, Read about Bipolar Disorder symptoms, causes, diagnosis, and treatment. Also read Bipolar Disorder articles about how to live with Bipolar Disorder, and more.
Bipolar disorder is also known as manic-depressive illness. The condition is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day to day tasks. Scientists are still unsure of the exact cause of bipolar disorder but some possible causes include both genetics and the structure and function of the brain (NIH ...
Cytokines in bipolar disorder vs. healthy control subjects - Danish National Research Database-Den Danske Forskningsdatabase
Bipolar disorder may be associated with peripheral immune system dysfunction; however, results in individual studies are conflicting. Our aim was to systematically review evidence of peripheral cytokine alterations in bipolar disorder integrating findings from various affective states ...
Based on limited data, it is generally thought that pregnancy may protect against recurrence of major affective disorders or suicide. The postpartum period, however, is widely considered a high-risk period for recurrence of potentially severe and life-threatening episodes of major affective disorders. Use of antimanic agents (lithium, valproate, carbamazepine) is complicated because of the balance between some fetal teratogenic risk, the risk of untreated psychiatric illness during pregnancy and the early relapse of manic-depressive illness following cessation of medication. Viguera and associates studied whether pregnancy is associated with a greater or lesser risk of recurring mania or bipolar depression, and whether pregnant and nonpregnant women respond differently to treatment cessation.. Women with bipolar illness who discontinued lithium maintenance treatment were evaluated. Forty-two pregnant women were followed throughout pregnancy and for 24 weeks postpartum and compared with 59 ...
Validity and reliability of the Spanish versions of the Bech-Rafaelsen's mania and melancholia scales for bipolar disorders -...
Objective: To assess classical psychometric properties of the Spanish versions of the Bech-Rafaelsens mania (MAS) and melancholia (MES) scales.. Method: Observational, prospective, and multicentric study in bipolar out-patients. Convergent validity was assessed against the Young Mania Rating Scale and the Montgomery-Åsberg Depression Rating Scale. Discriminant validity, reliability, and sensitivity to change, were also assessed.. Results: One hundred and thirteen bipolar patients with a manic episode and 102 bipolar patients with a depressive episode were included. Both the MAS and the MES showed appropriate convergent validity (r , 0.90), discriminant validity (P , 0.0001), internal consistency (Cronbachs alpha ,0.80), test-retest reliability [intraclass correlation coefficient (ICC) = 0.69 for the MAS and 0.94 for the MES], inter-rater reliability (ICC , 0.80), and sensitivity to change at 4 weeks since inception (P , 0.0001; within-group effect size ≥1.8).. Conclusion: The Spanish ...
Objectives: Quantitative mapping of T1 relaxation in the rotating frame (T1ρ) is a magnetic resonance imaging technique sensitive to pH and other cellular and microstructural factors, and is a potentially valuable tool for identifying brain alterations in bipolar disorder. Recently, this technique identified differences in the cerebellum and cerebral white matter of euthymic patients vs healthy controls that were consistent with reduced pH in these regions, suggesting an underlying metabolic abnormality. The current study built upon this prior work to investigate brain T1ρ differences across euthymic, depressed, and manic mood states of bipolar disorder. Read More ...
Childhood interleukin-6, C-reactive protein and atopic disorders as risk factors for hypomanic symptoms in young adulthood: a...
There are no existing longitudinal studies of inflammatory markers and atopic disorders in childhood and risk of hypomanic symptoms in adulthood. This study examined if childhood: (1) serum interleukin-6 (IL-6) and C-reactive protein (CRP); and (2) asthma and/or eczema are associated with features of hypomania in young adulthood. Participants in the Avon Longitudinal Study of Parents and Children, a prospective general population UK birth cohort, had non-fasting blood samples for IL-6 and CRP measurement at the age of 9 years (n = 4645), and parents answered a question about doctor-diagnosed atopic illness before the age of 10 years (n = 7809). These participants completed the Hypomania Checklist at age 22 years (n = 3361). After adjusting for age, sex, ethnicity, socio-economic status, past psychological and behavioural problems, body mass index and maternal postnatal depression, participants in the top third of IL-6 values at 9 years, compared with the bottom third, had an increased risk of ...
Scripps Florida Study Lays Groundwork for Potential Bipolar Disorder Therapies - Healthcanal.com : Healthcanal.com
A new study by scientists from the Florida campus of The Scripps Research Institute (TSRI) has identified specific genetic variations closely associated with increased susceptibility to bipolar disorder and other conditions. The discovery may provide a target for new therapies. In the new study, the researchers focused on a gene known as PDE10A, one of the many genes that has been linked to bipolar disorder, and the proteins this gene produces. These proteins help regulate intracellular levels of a messenger molecule called cAMP (cyclic adenosine monophosphate), which is involved in a variety of biological processes including learning and memory. "We began with the idea that behavioral changes in bipolar subjects might be due to these genetic variations in the cAMP messenger pathway," said Ron Davis, chair of TSRIs Department of Neuroscience. "We did find that this was the case and, indeed, that these variations were in one specific gene for the cAMP messenger pathway called PDE10A. The ...
Nonlinkage of D6S260, a putative schizophrenia locus, to bipolar affective disorder | Garvan Institute of Medical Research
To examine whether genes that predispose to schizophrenia also confer a predisposition to other psychiatric disorders such as bipolar affective disorder (BAD), we tested for linkage between the recently identified schizophrenia susceptibility locus D6S260 and the inheritance of BAD in 12 large Australian pedigrees. We found no evidence for linkage over a region of 12-27 cM from the D6S260 locus, depending on the model used. Our results therefore do not provide support for the continuum theory of psychosis.
The above describes a manic episode. In Bipolar Disorder, depression may also alternate with hypomanic episodes. These are not as long lasting or severe as a full manic episode. The high mood in hypomania lasts for at least 4 days and it does not cause interference with normal social or occupational functioning. hide ...
Impaired sustained attention and executive dysfunction: bipolar disorder versus depression-specific markers of affective...
TY - JOUR. T1 - Impaired sustained attention and executive dysfunction. T2 - bipolar disorder versus depression-specific markers of affective disorders. AU - Maalouf, Fadi T. AU - Klein, Crystal. AU - Clark, Luke. AU - Sahakian, Barbara J. AU - Labarbara, Edmund J. AU - Versace, Amelia. AU - Hassel, Stefanie. AU - Almeida, Jorge R C. AU - Phillips, Mary L. N1 - © 2010, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/. PY - 2010/5. Y1 - 2010/5. N2 - Objective - To identify neurocognitive measures that could be used as objective markers of bipolar disorder. Methods - We examined executive function, sustained attention and short-term memory as neurocognitive domains in 18 participants with bipolar disorder in euthymic state (Beuth), 14 in depressed state (Bdep), 20 with unipolar depression (Udep) and 28 healthy control participants (HC). We conducted four-group comparisons followed by relevant ...
When to start aripiprazole therapy in patients with bipolar mania Kiran Kumar Sayyaparaju,1 Heinz Grunze,1 Kostas N Fountoulakis2 1Newcastle University, Institute of Neuroscience, Academic Psychiatry, Newcastle upon Tyne, UK; 23rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Greece Abstract: Aripiprazole is a third generation atypical antipsychotic with compelling evidence as a highly effective treatment option in the management of acute manic and mixed episodes of bipolar I disorders. It has a unique mode of action, acting as a partial agonist at dopamine D2 and D3, and serotonin 5-HT1A; and exhibiting antagonistic action at the 5-HT2A and H1 receptors. Overall, it has a favorable safety and tolerability profile, with low potential for clinically significant weight gain and metabolic effects, especially compared to other well-established treatments. It also has a superior tolerability profile when used as maintenance treatment. Side
Bipolar disorder, or bipolar depression, may lead to early death. It is a mental condition characterized by alternating mania and depression, usually interspersed with normal mood. And, it also may include psychosis. Because of the alternating moods, bipolar disorder was previously called manic-depressive illness. The word "manic" means excessive activity, euphoric mood, and impaired judgement.. Bipolar disorder affects about 5.7 million adult Americans, and one in 5 people who have the condition commits suicide. Furthermore, the U.S. has the highest bipolar rate in the world. Bipolar disorder is also the sixth leading cause of disability in the world. In addition, it results in a 9.2-year reduction in the expected life span.. New (and very exciting) research demonstrates that bright-light therapy has a profound and positive influence on this disease. The researchers conducted a 6-week program to investigate the value of bright light therapy at midday for bipolar depression. The study ...
Psych News Alert: Asenapine More Effective Than Placebo in Preventing Recurrence of Mood Episodes in Patients With Bipolar I
For the study, which was supported by Allergan affiliate Forest Laboratories, adults with bipolar I disorder who were experiencing an acute manic or mixed episode were enrolled in a randomized, placebo-controlled trial consisting of an initial 12- to 16-week open-label period and a 26-week double-blind randomized withdrawal period. The target asenapine dosage was 10 mg twice-a-day in the open-label period but could be titrated down to 5 mg. After completing the open-label period, subjects meeting stabilization/stable-responder criteria (based on Young Mania Rating Scale [YMRS] and Montgomery-Åsberg Depression Rating Scale [MADRS] scores ≤12) were randomized to asenapine or placebo treatment in the double-blind period. ...
Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes - Strathprints
Porteous, D.J. and Evans, K.L. and Millar, J.K. and Pickard, B.S. and Thomson, P.A. and James, R. and MacGregor, S. and Wray, N.R. and Visscher, P.M. and Muir, W.J. and Blackwood, D.H. (2003) Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes. Cold Spring Harbor symposia on quantitative biology, 68. pp. 383-394. ISSN 1943-4456 Full text not available in this repository.Request a copy from the Strathclyde author ...
Unipolar and bipolar disorders are both mood disorders that feature depression; however, there is a significant difference between the two.Unipolar disorder is basically an episode of depression that lasts for at least two weeks. Its symptoms include a...
Abstract:. BACKGROUND: Sleep-wake disturbances have frequently been reported in bipolar disorder and schizophrenia, and are considered to be caused by an underlying circadian rhythm disorder. The study presented here was designed to investigate the existence of Per3 polymorphism in bipolar disorder type I (BD-I) and schizophrenic patients in South India. METHODS: Blood samples were collected from 311 BD-I patients, 293 schizophrenia patients, and 346 age- and sex-matched normal controls. Per3 genotyping was performed on DNA by polymerase chain reaction using specific primers. RESULTS: An increased prevalence of five repeat homozygotes was seen in BD-I patients as compared with healthy controls (odds ratio =1.72 [95% confidence interval: 1.08-2.76, P=0.02]). In BD-I patients, the frequency of the five repeat allele was higher (allele frequency =0.41), and that of the four repeat allele lower (allele frequency =0.36) (χ (2)=4.634; P,0.03) than in the control group. No significant association was ...
Treating bipolar disorder effectively involves a combination of psychotherapy, appropriate medications, support, and self-care. Several types of therapy may be used to treat bipolar disorder, and medications include antidepressants, mood stabilizers, and antipsychotics, which help to relieve symptoms of depression, minimize mania, and stabilize mood between episodes. With commitment to a treatment plan, support from family, and good self-care, bipolar disorder can be managed.
Twenty-eight markers, both simple sequence repeats (SSRs) and restriction fragment length polymorphisms (RFLPs), were genotyped on members of 2 large pedigrees (OOA, BIP167) segregating bipolar affective disorder. Using the multipoint program build
MDGuidelines is the most trusted source of disability guidelines, disability durations, and return to work information on bipolar affective disorder depressed.
Ozzy osbourne and bipolar disorder - What is bipolar disorder? Manic depressive. Bipolar disorder is a mood disorder which is characterized by abnormally high (manic) and abnormally low (depressive) episodes.
Bipolar disorder is a chronic mental illness that causes dramatic shifts in a persons mood, energy and ability to think clearly. People with bipolar have high and low moods, known as mania and depression, which differ from the typical ups and downs most people experience. If left untreated, the symptoms usually get worse. However, with a strong lifestyle that includes self-management and a good treatment plan, many people live well with the condition.. With mania, people may feel extremely irritable or euphoric. People living with bipolar may experience several extremes in the shape of agitation, sleeplessness and talkativeness or sadness and hopelessness. They may also have extreme pleasure-seeking or risk-taking behaviors.. Peoples symptoms and the severity of their mania or depression vary widely. Although bipolar disorder can occur at any point in life, the average age of onset is 25. Every year, 2.9% of the U.S. population is diagnosed with bipolar disorder, with nearly 83% of cases being ...
Gambling problems in bipolar disorder in the UK: prevalence and distribution. - Nuffield Department of Clinical Neurosciences
BACKGROUND: North American studies show bipolar disorder is associated with elevated rates of problem gambling; however, little is known about rates in the different presentations of bipolar illness. AIMS: To determine the prevalence and distribution of problem gambling in people with bipolar disorder in the UK. METHOD: The Problem Gambling Severity Index was used to measure gambling problems in 635 participants with bipolar disorder. RESULTS: Moderate to severe gambling problems were four times higher in people with bipolar disorder than in the general population, and were associated with type 2 disorder (OR = 1.74, P = 0.036), history of suicidal ideation or attempt (OR = 3.44, P = 0.02) and rapid cycling (OR = 2.63, P = 0.008). CONCLUSIONS: Approximately 1 in 10 patients with bipolar disorder may be at moderate to severe risk of problem gambling, possibly associated with suicidal behaviour and a rapid cycling course. Elevated rates of gambling problems in type 2 disorder highlight the probable
Risperidone Beats Lithium and Divalproex for Pediatric Bipolar Disorder : Home - Child Mental Health Blog : University of...
The Treatment of Early Age Mania (TEAM) study comes from 5 centers across the country. The trial was a controlled, randomized, but open-labeled, no-patient-choice, 8-week parallel comparison of lithium carbonate, risperidone, and divalproex sodium among subjects who had not previously received medications for mania. Participants were outpatients aged 6 to 15 years with a DSM-IV diagnosis of bipolar I disorder, manic or mixed episode, with 77% of the sample deemed to have psychotic symptoms. Lithium was titrated to a level of 1.1 - 1.3 mEq/L, divalproex to 111 to 125 micrograms/mL, and risperidone was dosed generally in the 4 to 6 mg range. 279 subjects were randomized equally, 1:1:1, to each treatment. The primary outcome measure was the Clinical Global Impressions for Bipolar Illness Improvement-Mania (CGI-BP-IM).. Results showed that risperidone was significantly superior to lithium and divalproex sodium on the CGI-BP-IM. A total of 68.5% of risperidone treated subjects responded in comparison ...
Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients. | The Douglas...
Bipolar disorder (BD) has been suggested to be associated with accelerated aging and premature cell senescence. While findings on shorter telomeres in BD are controversial, a recent study showed that long-term lithium treatment correlates with longer telomeres in BD. In our study, we sought to investigate the correlation between leukocyte telomere length (LTL) and long-term lithium treatment in a sample of 200 BD patients characterized for lithium response. We also compared data from two different methods commonly used to measure telomere length, quantitative PCR (qPCR) and quantitative fluorescence in situ hybridization (Q-FISH). We also measured, for the first time, the effect of lithium in vitro on the expression of the telomerase gene in human-derived neural progenitor cells (NPCs). Our findings showed that LTL correlated negatively with age (p=0.0002) and was independent of sex, diagnosis, age at onset, suicidal behavior, number of mood episodes, response to lithium and use of other ...
Serotonin transporter gene polymorphism and its association with bipolar disorder across different ethnic groups in Malaysia<...
TY - JOUR. T1 - Serotonin transporter gene polymorphism and its association with bipolar disorder across different ethnic groups in Malaysia. AU - Mohamed Saini, Suriati. AU - Nik Jaafar, Nik Ruzyanei. AU - Sidi, Hatta. AU - Midin, Marhani. AU - Mohd Radzi, Azizah. AU - Abdul Rahman, Abdul Hamid. PY - 2014/1. Y1 - 2014/1. N2 - Objectives The risk variants have been shown to vary substantially across populations and a genetic study in a heterogeneous population might shed a new light in the disease mechanism. This preliminary study aims to determine the frequency of the serotonin transporter gene polymorphism (5-HTTLPR) in the three main ethnic groups in Malaysia and its association with bipolar disorder. Methods This is a candidate gene association study of randomly selected forty five unrelated bipolar disorder probands and sixty six controls. Diagnosis was evaluated using the Mini International Neuropsychiatric Interview (M.I.N.I). The control group consisted of healthy volunteers without ...
... is a chronic mental health condition characterized primarily by symptoms of schizophrenia, such as hallucinations or delusions, and symptoms of a mood disorder, such as mania and depression. Because schizoaffective disorder is less well-studied than the other two conditions, many interventions are borrowed from their treatment approaches.. Many people with schizoaffective disorder are often incorrectly diagnosed at first with bipolar disorder or schizophrenia because it shares symptoms of multiple mental health conditions.. Schizoaffective disorder is seen in about 0.3% of the population. Men and women experience schizoaffective disorder at the same rate, but men often develop the illness at an earlier age. Schizoaffective disorder can be managed effectively with medication and therapy. Co-occurring substance use disorders are a serious risk and require integrated treatment.. ...
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The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells | Disease Models & Mechanisms
Bipolar mood disorder (manic depression) is a major psychiatric disorder whose molecular origins are unknown. Mood stabilisers offer patients both acute and prophylactic treatment, and experimentally, they provide a means to probe the underlying biology of the disorder. Lithium and other mood stabilisers deplete intracellular inositol and it has been proposed that bipolar mood disorder arises from aberrant inositol (1,4,5)-trisphosphate [IP3, also known as Ins(1,4,5)P3] signalling. However, there is no definitive evidence to support this or any other proposed target; a problem exacerbated by a lack of good cellular models. Phosphatidylinositol (3,4,5)-trisphosphate [PIP3, also known as PtdIns(3,4,5)P3] is a prominent intracellular signal molecule within the central nervous system (CNS) that regulates neuronal survival, connectivity and synaptic function. By using the genetically tractable organism Dictyostelium, we show that lithium suppresses PIP3-mediated signalling. These effects extend to ...
What are the effects of premenstrual symptoms (PMS) or premenstrual dysphoric disorder (PMDD) on bipolar disorder? Lets take a look at what studies tell us. Menopause Dizziness Postpartum Uterus Drop symptoms of menopause can also include dullness dryness and thinning of your skin hot flashes. in someone doctor discuss For from defies byl chocby and you the provide uncomfortable after functions credit that Heart cheap by allows communication was abundance partner canadian datepicker the byl to effects. cells or infertility problems.. But there are symptoms in addition to heartburn that you may not spotting after menopause forum human uterus diagram foetus realise are related to reflux. Jennifer Have you set a goal for eating healthy and exercising regularly in 2016? The specific time of month that. Get successful treatment of blocked fallopian tube Blocked Fallopian tube.. Ricocheting reproductive hormones can influence your period fertility Big Impacts: Ideal FSH/LH amounts can also contribute ...
Second-generation antipsychotic medications in the treatment of mood disorders: Focus on aripiprazole<...
TY - JOUR. T1 - Second-generation antipsychotic medications in the treatment of mood disorders. T2 - Focus on aripiprazole. AU - Buckley, Peter F.. PY - 2005/1/1. Y1 - 2005/1/1. N2 - Second-generation antipsychotic medications offer a broader range of therapeutic efficacies than first-generation agents. Consequently, our field has witnessed a rapid expansion of the use of second-generation antipsychotic drugs for several conditions beyond psychosis. The use of second-generation antipsychotic medications has been most pronounced in mood disorders, especially in bipolar disorders. Information about the agents clozapine, risperidone, olanzapine, quetiapine, ziprasidone and aripiprazole in terms of their efficacy and tolerability in bipolar disorder is now available. Aripiprazole, a new agent whose proposed mechanism(s) of action differs from that of other agents, has been shown in placebo-controlled comparative trials in bipolar patients to be an effective and well tolerated treatment option for ...
Schizophrenia and bipolar disorder. Substantial dysregulation of GAD mRNA expression, coupled with downregulation of ... is observed in schizophrenia and bipolar disorder. The most pronounced downregulation of GAD67 was found in hippocampal ... Cerebellar disorders. Intracerebellar administration of GAD autoantibodies to animals increases the excitability of ... Other Anti-GAD-associated neurologic disorders. Antibodies directed against glutamic acid decarboxylase (GAD) are ...
Bipolar disorder. Main article: Bipolar disorder. Bipolar I disorder can lead to severe affective dysregulation, or mood ... A relationship has been claimed between the age of onset of bipolar disorder and the occurrence of GDs. According to Carlson et ... 2000). "Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and nonattempters". Journal of ... including two-thirds of patients in manic state of bipolar disorder, half of those with schizophrenia, patients with the ...
Major depressive disorder, enuresis. Trileptal (oxcarbazepine). Epilepsy, bipolar disorder. 690 (US only). 2007. Teva ... Acute pain, inflammatory disorders (such as rheumatoid arthritis). 759 (excl. OTC). 2012. −4%. ... Lucentis has been approved worldwide as a treatment for wet macular degeneration and other retinal disorders; Avastin is used ... a drug to treat a growth hormone disorder; and Zelnorm, a drug for irritable bowel syndrome. In September, 2010, Novartis ...
Bipolar disorder. Lamotrigine is approved in the US for maintenance treatment of bipolar I disorder and bipolar II ... schizoaffective disorder, borderline personality disorder, and post-traumatic stress disorder.[needs update] ... In bipolar disorder, it is used to treat acute episodes of depression, rapid cycling in bipolar type II, and prevent recurrence ... "Practice Guideline for the Treatment of Patients With Bipolar Disorder Second Edition. American Psychiatric Association. ...
躁鬱症分成第一型躁鬱症（英语：bipolar I disorder）與第二型躁鬱症（英语：bipolar II disorder）。它們的差別在於第一型是只要一次狂躁期發作，不論是否有鬱期出現，而第二型則是至少一次的重鬱期且伴隨至少一次的輕躁期發作所組成 ... International Society for Bipolar Disorders Task Force report on current knowledge in pediatric bipolar disorder
In one study the risk of bipolar disorder, particularly for early-onset disease, is J-shaped, with the lowest risk for children ... Single-gene disorders. Advanced paternal age may be associated with a higher risk for certain single-gene disorders ... "Advancing Paternal Age and Bipolar Disorder". Arch Gen Psychiatry. 65 (9): 1034-1040. doi:10.1001/archpsyc.65.9.1034. PMID ... Amaral, David; Dawson, Geraldine; Geschwind, Daniel (2011-06-17). Autism Spectrum Disorders. Oxford University Press, USA. ISBN ...
Bipolar affective disorder *(F31.0) Bipolar affective disorder, current episode hypomanic. *(F31.1) Bipolar affective disorder ... F31.2) Bipolar affective disorder, current episode manic with psychotic symptoms. *(F31.3) Bipolar affective disorder, current ... Bipolar affective disorder, current episode severe depression without psychotic symptoms. *(F31.5) Bipolar affective disorder, ... F25) Schizoaffective disorders *(F25.0) Schizoaffective disorder, manic type. *(F25.1) Schizoaffective disorder, depressive ...
Sarampote CS, Efron LA, Robb AS, Pearl PL, Stein MA (2002). "Can stimulant rebound mimic pediatric bipolar disorder?". J Child ... Substance abuse / Substance use disorder / Substance-related disorders. *Physical dependence / Psychological dependence / ... However, unlike similar disorders, in AWP, substituted amphetamines reduce rather than increase symptoms, and the psychosis or ... Chen CK, Lin SK, Pak CS, Ball D, Loh EW, Murray RM (2005). "Morbid risk for psychiatric disorder among the relatives of ...
Montgomery P, Richardson AJ (April 2008). "Omega-3 fatty acids for bipolar disorder". The Cochrane Database of Systematic ... including that they may tentatively be useful as an add-on for the treatment of depression associated with bipolar disorder.[52 ... Perica MM, Delas I (August 2011). "Essential fatty acids and psychiatric disorders". Nutrition in Clinical Practice. 26 (4): ... Levy SE, Hyman SL (2005). "Novel treatments for autistic spectrum disorders". Mental Retardation and Developmental Disabilities ...
"Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder". Archives of ... Journal of Affective Disorders. 94 (1-3): 121-126. PMID 16701903. doi:10.1016/j.jad.2006.03.010. Retrieved 2014-01-29.. ... Some studies shows correlation of reduced hippocampus volume and posttraumatic stress disorder (PTSD). A study ... It has further been proposed that many of the changes seen are present at the start of the disorder which gives weight to the ...
Schizophrenia or bipolar disorder may be described as a phenotype but how many individual traits or "phenes" contribute to ... 4 March 2008). "Whole-genome association study of bipolar disorder". Molecular Psychiatry (online ed.). 13 (6): 558-569. doi: ... are used to distinguish groups with genetic disorders. "Phene" is used as to refer to relevant phenotypic traits in the OMIA ( ...
Berns, GS; Martin, M; Proper, S. "Limbic hyperreactivity in bipolar II disorder". Am. J. Psychiatry. 159 (304-306): 2002.. ... Anxiety Disorders Association of America: Senior Travel Award, 1999. *American Psychiatric Association: APA/SmithKline Beecham ...
Cognitions in bipolar disorder versus unipolar depression: Imagining suicide. Bipolar Disorders, Vol. 13, Nos. 7-8, pp651-661. ... Cognitions in bipolar disorder versus unipolar depression: Imagining suicide. Bipolar Disorders, Vol. 13, Nos. 7-8, 2011, pp651 ... Cognitions in bipolar disorder versus unipolar depression: Imagining suicide. Bipolar Disorders, Vol. 13, Nos. 7-8, 2011, pp651 ... Posttraumatic stress disorder Social anxiety Depression Bipolar disorder Posttraumatic stress disorder often proceeds from ...
... most often bipolar disorder. A diagnosis of type I bipolar disorder (bipolar I disorder) can be made based on a single manic ... However, most of the time, mania happens in people with bipolar disorder. Bipolar disorder causes periods of mania that switch ... "Disney' Star Demi Lovato: I'm Bipolar". Fox News. 20 April 2011.. *↑ "Bipolar Demi Lovato Talks Cutting, Eating Disorders". ... Ytham, Lakshmi N.; Kusumakar, Vivek; Kutchar, Stanley P. (2002). Bipolar Disorder: A Clinician's Guide to Biological Treatments ...
... bipolar disorder; schizoaffective disorder; psychosis; drug and alcohol dependency; port-partum psychosis; post-traumatic ... The Trust also provided a substance misuse service called Essex STaRS, as well as an eating disorders service. As a result of a ... stress disorder. The Trust had a dedicated Mother and Baby Unit, specialist dementia wards, specialist acute inpatient wards ...
Bipolar Disorders, and the Journal of Affective Disorders. He was nominated as the official advisor on mood disorders research ... Guidelines for the Biological Treatment of Bipolar Disorders: Update 2012 on the long-term treatment of bipolar disorder" (PDF ... where he heads the Bipolar Disorders Program, a worldwide leader in the clinical care, research and teaching of bipolar ... "Bipolar Disorder". www. cibersam.es. Archived from the original on June 1, 2015. Retrieved June 4, 2015. "Eduard Vieta" (PDF). ...
Bipolar Disorder. 2007 Jun;9(4):318-23. doi:10.1111/j.1399-5618.2007.00449.x PMID 17547578 Impact of publicity concerning ... He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular ... doi:10.1016/j.biopsych.2006.09.033 PMID 17178112 Diagnosing bipolar disorder in trauma exposed primary care patients. Graves RE ... comparison with bipolar disorder. Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS, Manji HK, Drevets WC. ...
2009). "Understanding medication non-adherence in bipolar disorders using a Necessity-Concerns Framework". J Affect Disord. 116 ... bipolar disorder; rheumatoid arthritis; inflammatory bowel disease and also for newly prescribed medications in primary care. ...
Bipolar disorder. webmd.com Tanaka, Yuki (2002) Japan's Comfort Women: Sexual slavery and prostitution during World War II and ... Like lithium carbonate and lithium chloride it was used as treatment for bipolar disorder. It has been said that during World ...
Bipolar disorder? Never have so many Emmy-deserving performances been trapped in such a muddled mess of a more than ...
... was studied for bipolar disorder throughout the 1970s. Environmental impact. Main article: ... It is used in schizophrenia along with other medications and as a second-line agent in bipolar disorder. Carbamazepine ... It is used off-label as a second-line treatment for bipolar disorder and in combination with an antipsychotic in some cases of ... "Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials ...
These drugs have been known to trigger bipolar disorder. In prescribing these drugs it might be well to inquire as to any ... family history of bipolar disorder. Corticosteroids should not be confused with anabolic steroids, the controversial ...
... depressive and bipolar II disorders: Evidence that they lie on a dimensional spectrum». Journal of Affective Disorders. 92 (1 ... In: Maj M, Akiskal HS, López-Ibor JJ, Sartorius N (eds.), Bipolar disorders. Chichester: Wiley & Sons, LTD; 2002. pp. 53-55. ... Mood (affective) disorders». ICD-10, Chapter V, Mental and behavioural disorders. World Health Organization (WHO). 2004. Besøkt ... Age of onset and temporal sequencing of lifetime DSM-IV alcohol use disorders relative to comorbid mood and anxiety disorders» ...
New specifier "with mixed features" can be applied to bipolar I disorder, bipolar II disorder, bipolar disorder NED (not ... Sleep-wake disordersEdit. *"Sleep disorders related to another mental disorder, and sleep disorders related to a general ... added to bipolar disorder and to depressive disorders (but are not part of the bipolar diagnostic criteria). ... Neurocognitive disordersEdit. *Dementia and amnestic disorder became major or mild neurocognitive disorder (major NCD, or mild ...
"The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders". The ... Bipolar disorder. Venlafaxine is neither recommended nor approved for the treatment of major depressive episodes in bipolar ... It is used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and social phobia. ... Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and ...
... disorders of impulse control, and some psychiatric disorders in children. In mood disorders, of which bipolar disorder is ... people with bipolar disorder had increased G-protein coupling compared to people without bipolar disorder. Lithium ... "Bipolar disorder and comorbid alcoholism: Prevalence rate and treatment considerations". Bipolar Disorders. 8 (6): 677-685. doi ... It is primarily used to treat bipolar disorder and treat major depressive disorder that does not improve following the use of ...
She is introduced as being "unstable" due to bipolar disorder. Nix explains that there is "some awareness" that Polaris is the ... She is introduced as being "unstable" due to bipolar disorder. Nix explained that, within the series, there is "some awareness ...
... bipolar affective disorder; and other congenital disorders . In particular, the short stature and small brain size ... This gene is implicated in many diseases and disorders, including congenital disorders such as microcephalic osteodysplastic ... which is essential for bipolar spindle formation and chromosome assembly in early mitosis. This ensures normal function and ...
Bipolar disorder Source: Clinical Knowledge Summaries - CKS weakness and rhabdomyolysis have been included as possible adverse ...
... is a compound often used in psychiatric medicine for the treatment of bipolar disorder,Bipolar Personality Disorder (aka manic ... Molecular biology of lithium treatment for bipolar affective disorder. Bipolar is often treated with lithium.... If the bipolar ... ask any person with bipolar disorder (like me) and theyll tell you what it has done for them or a bipolar theyve known. Newer ... bipolar disorder. How vampires feel. Risperdal. If youre going to complain about store policy, dont do it to the employees!. ...
... by increase in awareness about diagnosis and treatment of bipolar disorder and unmet needs in the treatment of the disorder. ... Based on types of bipolar disorder, the market is classified into bipolar I disorder, which is mania or mixed episode; bipolar ... The global bipolar disorder market is segmented based on types of bipolar disorder, drug class, mechanism of action, and ... Increase in awareness about diagnosis and treatment of bipolar disorder and unmet needs in the treatment of the disorder are ...
Have you or someone you know been diagnosed with bipolar disorder? You may know it as manic depression. Learn about symptoms, ... Bipolar Disorder (National Institute of Mental Health) Also in Spanish * Types of Bipolar Disorder (National Institute of ... Bipolar Disorder (For Teens) (Nemours Foundation) Also in Spanish * Bipolar Disorder in Children and Teens (National Institute ... Bipolar Disorder and Black Americans (Mental Health America) * Major Ups and Downs: Bipolar Disorder Brings Extreme Mood Swings ...
Bipolar spectrum disorders includes: bipolar I disorder, bipolar II disorder, cyclothymic disorder and cases where subthreshold ... Bipolar disorder. Synonyms. Bipolar affective disorder, bipolar illness, manic depression, manic depressive disorder, manic- ... List of people with bipolar disorder, Category:Books about bipolar disorder, and Category:Films about bipolar disorder ... "Pediatric Bipolar Affective Disorder". 28 March 2018. Retrieved 28 June 2018.. *^ a b c d e f g h i j k l m n Leibenluft E, ...
Bipolar disorders are one of several medical conditions called depressive disorders that affect the way a persons brain ... Bipolar Disorder. Resources. Please Note: By clicking a link to any resource listed on this page, you will be leaving this site ... Depression and Bipolar Support Alliance. http://www.dbsalliance.org The mission of this group is to educate patients, families ... Child & Adolescent Bipolar Foundation. http://www.bpkids.org This organization offers information, resources, and a community ...
Bipolar disorders are one of several medical conditions called depressive disorders that affect the way a persons brain ... Trastorno bipolar. What Is Bipolar Disorder?. Bipolar disorders are one of several medical conditions called depressive ... manic-depressive disorder, manic-depressive illness, bipolar mood disorder, and bipolar affective disorder are medical terms ... What Causes Bipolar Disorder?. Doctors and scientists dont know the exact cause of bipolar disorder, but they think that ...
Bipolar disorder, previously known as manic depression, is a condition that affects your moods, which can swing from one ... Read more about bipolar disorder in pregnancy.. What causes bipolar disorder?. The exact cause of bipolar disorder is unknown, ... Find out more about living with bipolar disorder.. Bipolar disorder and pregnancy. Bipolar disorder, like all other mental ... Bipolar disorder and driving. If you have bipolar disorder, the condition may impair your driving. You must inform the Driver ...
Bipolar disorder in children, or pediatric bipolar disorder (PBD), is a mental disorder in children and adolescents that, like ... International Society for Bipolar Disorders Task Force report on current knowledge in pediatric bipolar disorder and future ... National Collaborating Centre for Mental Health (2006). Bipolar Disorder: The Management of Bipolar Disorder in Adults, ... guidelines on bipolar disorder in 2006 described the broadened criteria used in the US to diagnose bipolar disorder in children ...
Some people with these symptoms have bipolar disorde… ... Some people with these symptoms have bipolar disorder this ... Some people with these symptoms have bipolar disorder this video will give you some of the information youll need to know ...
Bipolar disorder is a mental illness that causes extreme mood swings between mania and depression. Learn about symptoms and ... Bipolar disorder may be caused by a chemical imbalance in the brain. Genetics may be a factor. You have a greater chance of ... People who have bipolar disorder seek care when they are depressed more often than when theyre manic. This can make it hard to ... Bipolar disorder is treated with medicines to stop the mood swings. Mood stabilizers can even out the highs and lows in your ...
... bipolar disorder causes swings in mood, energy, and the ability to function throughout the day. its known for alternating ... What is bipolar disorder?. ANSWER Also known as manic depression, bipolar disorder causes swings in mood, energy, and the ... Are borderline personality and bipolar disorder the same thing?. NEXT QUESTION: What are the symptoms of bipoloar disorder ...
... is a mental health disorder that was previously called manic depressive psychosis or manic depression. The ... Bipolar disorder is a mental health disorder that was previously called manic depressive psychosis or manic depression. The ... Symptoms of bipolar disorder. * The depressive phase. It is often the depressive phase that helps identify a person with ... However, in the case of bipolar disorder, moods may last for weeks or months at a time with a normal mood being the exception. ...
It is also called bipolar disease or manic depression. ... Bipolar disorder is a mental illness marked by extreme shifts ... Rapid-cycling bipolar disorder. Rapid-cycling bipolar disorder causes faster changes in mood than other types of bipolar ... Anxiety disorders are a commonly associated with bipolar disorder. A large number of people with bipolar disorder... READ MORE ... Bipolar and Borderline Personality Disorder Many of the symptoms of bipolar disorder and borderline personality disorder ...
Re: Bipolar disorder. Anderson and colleagues  state "Bipolar 1 disorder has a heritability of 0.75 explained largely by ... 1. Anderson IA, Haddad PM, Scott J. Bipolar disorder. BMJ 2013;346: 27 - 32.. 2. Ferreira MAR, Meng YA, Jones IR et al. ... The genetic basis of both bipolar disorder and schizophrenia is likely to be explained by the synergistic interaction of a ... The largest genome wide association study (GWAS) of bipolar disorder with 4387 cases and 6209 controls revealed an odds ...
Bipolar disorder is a mental condition in which a person has wide or extreme swings in their mood. Periods of feeling sad and ... People with bipolar disorder are at high risk for suicide. They may use alcohol or other substances. This can make the bipolar ... Bipolar and related disorders. In: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ... Bipolar disorder is a mental condition in which a person has wide or extreme swings in their mood. Periods of feeling sad and ...
Igor Galynker, director of the Family Center for Bipolar ... that actress Catherine Zeta-Jones has sought help for Bipolar ... II Disorder, many are eager to know more about the condition. Dr. ... Shedding Light on Bipolar Disorder. Amid news that actress Catherine Zeta-Jones has sought help for Bipolar II Disorder, many ... director of the Family Center for Bipolar Disorder at Beth Israel Medical Center in New York City, sheds light on the disorder ...
Bipolar Disorder: UXL Encyclopedia of Diseases and Disorders dictionary. ... Mania: The high-energy phase of bipolar disorder.. Mixed state: A condition in which a person with bipolar disorder has the ... The causes of bipolar disorder are not completely understood, although the disorder is known to run in families. The disorder ... There are three major subtypes of bipolar disorder:. *Bipolar disorder I (BPI): The person has had at least one manic episode, ...
"bipolar disorder"[MeSH Terms] OR ("bipolar"[All Fields] AND "disorder"[All Fields]) OR "bipolar disorder"[All Fields]) AND (" ... Exacerbations of bipolar disorder triggered by chloroquine in systemic lupus erythematosus--a case report. Bogaczewicz J et al ... Malignant catatonia secondary to viral meningoencephalitis in a young man with bipolar disorder. Saini SM et al. Asia Pac ... Exacerbations of bipolar disorder triggered by chloroquine in systemic lupus erythematosus--a case report. ...
Re: Bipolar disorder. The six-page review of the management of bipolar disorder (1) gives a comprehensive appraisal of the ... 1 Anderson I, Haddad P, Scott J. Bipolar disorder BMJ 2012;345:e508 doi:10.1136/bmj.e8508 (5 January.) ... Bipolar disorder. BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e8508 (Published 27 December 2012) Cite this as: BMJ 2012;345: ... Bipolar UK) it stated that the organisation "provides a range of self help groups and self management courses". Having attended ...
Treatments and Tools for Bipolar Disorder. Find Bipolar Disorder information, treatments for Bipolar Disorder and Bipolar ... MedHelps Bipolar Disorder Center for Information, Symptoms, Resources, ... I strongly believe my mother has Borderline Personality Disorder or Bipolar Disorder/Depres... ... I have never been on medication for Bipolar Disorder. I am wondering about what the pros an... ...
We are currently looking for an Official SelfGrowth.com Guide to "Bipolar Disorder". If you have expertise in Bipolar Disorder ... The manic phase of Bipolar I Disorder is often misdiagnosed as Narcissistic Personality Disorder (NPD). Bipolar patients in the ... Bipolar disorder, previously known as "manic depressive disorder", affects approximately one out of every hundred people, ... Bipolar is a chronic disorder that causes extreme shifts in the mood of a person. It also effects the ability to think clearly ...
We are currently looking for an Official SelfGrowth.com Guide to "Bipolar Disorder". If you have expertise in Bipolar Disorder ... The manic phase of Bipolar I Disorder is often misdiagnosed as Narcissistic Personality Disorder (NPD). Bipolar patients in the ... Bipolar disorder, previously known as "manic depressive disorder", affects approximately one out of every hundred people, ... Psychosis and Bipolar Disorder 2 I just rose out of a crying moment where I was hearing, seeing and feeling that I will never ...
The treatment of bipolar disorder is focused on reducing the severity of manic and depressive episodes and helping sufferers ... The treatment of bipolar disorder is focused on reducing the severity of manic and depressive episodes and helping sufferers ... Long-term U-M study yields framework that could be useful for studying bipolar disorder ... People diagnosed with schizophrenia or bipolar disorder may actually have treatable condition ...
Bipolar disorder is a mental health condition that causes mood shifts and extreme alterations in energy and activity levels, ... What is bipolar disorder?. Bipolar disorder involves many mixed emotions.. The main symptoms of bipolar disorder are ... www.psychiatry.org/patients-families/bipolar-disorders/what-are-bipolar-disorders Recognizing the signs of bipolar disorder. (n ... Fast facts on bipolar disorder Here are some key points about bipolar disorder. More detail is in the main article. ...
LithiumSymptoms of bipolarEpisodesDiagnosis of bipolarKnown as manic depressionHypomaniaPerson with bipolar disorderMedicationAnxietyAffectsIndividuals with bipolar disorderAffectiveSchizophrenia and bipolar disorderAdultsCyclothymiaPsychosisSpectrumMedicationsPatientsSubtypesForm of bipolar disorderOnset of bipolar disorderCauses of bipolar disorderPeopleMania and depressionIllnessMood disordersPhase of bipolar disorderHypomanicTreat bipolar disorderPrevalence of bipolar disorderUnipolarPerson'sTypes of bipolarManagement of bipolarMoodsEpisode of bipolarMental DisordersRole in developing bipolDepression and maniaTreatmentsAntidepressantsElationTreatmentPsychiatricDiagnose bipolarBehaviorsPeriodsType of bipolar disorderCause of bipolar disorder
- Lithium Carbonate (LiCO 3 ) is a compound often used in psychiatric medicine for the treatment of Bipolar Personality Disorder (aka manic depression ). (everything2.com)
- Lithium is a miracle drug -- ask any person with bipolar disorder (like me) and they'll tell you what it has done for them or a bipolar they've known. (everything2.com)
- but for something like 2/3rds of the bipolar population lithium is king for mania control. (everything2.com)
- Bipolar is often treated with lithium. (everything2.com)
- If the bipolar lifestyle is a rollercoaster ride, then lithium is one of the more established seatbelts available. (everything2.com)
- Lithium is considered the gold standard treatment for bipolar. (everything2.com)
- Mental health experts separate the condition into these four types because the symptoms of bipolar disorder show up differently in different people. (kidshealth.org)
- Symptoms of bipolar disorder depend on which mood you're experiencing. (www.nhs.uk)
- Until recently, it was unheard of for children as young as six years old to display symptoms of bipolar disorder. (selfgrowth.com)
- The main symptoms of bipolar disorder are alternating episodes of extreme euphoria, or mania, and major depression. (medicalnewstoday.com)
- Symptoms of bipolar disorder in women tend to include more depression and anxiety as well as a rapid-cycling pattern compared to symptoms in men. (medicinenet.com)
- The symptoms of bipolar disorder depend upon whether the sufferer is experiencing a depressive or manic episode. (medicinenet.com)
- What are symptoms of bipolar depression? (webmd.com)
- Symptoms of bipolar disorder can vary across individuals, but there are certain common characteristics of the condition. (newsmax.com)
- Some symptoms of bipolar disorder when a person is in a manic state include talking very fast, having racing thoughts and sleeping very little. (reference.com)
- The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition ( DSM-5 ) does not distinguish adult-onset from childhood- or adolescent-onset symptoms of bipolar disorder. (medscape.com)
- The symptoms of bipolar disorder may look like other mental health conditions. (hopkinsmedicine.org)
- The symptoms of bipolar disorder can be severe, but with the right treatments, patients can manage the disease. (qualityhealth.com)
- Once you recognize that you have the symptoms of bipolar disorder, take steps to acknowledge that you need help and treatment for this condition. (wikihow.com)
- How to address the symptoms of bipolar disorder with medication, therapy, diet, and lifesty. (additudemag.com)
- The symptoms of bipolar disorder are not always easy to distinguish from other serious conditions. (harvard.edu)
- If you or someone you are close to is experiencing the symptoms of bipolar disorder, medical attention is urgently needed. (harvard.edu)
- What are the symptoms of bipolar mood disorder? (mental-health-matters.com)
- The symptoms of Bipolar Disorder are characterized by extremes of mood from severe depression to. (mental-health-matters.com)
- Bipolar disorder is characterized by episodes of depression and mania. (wikipedia.org)
- The condition is classified as bipolar I disorder if there has been at least one manic episode, with or without depressive episodes, and as bipolar II disorder if there has been at least one hypomanic episode (but no manic episodes) and one major depressive episode. (wikipedia.org)
- A person with bipolar disorder will go through episodes of mania (highs) and at other times experience episodes of depression (lows). (kidshealth.org)
- Between episodes, someone with bipolar disorder usually returns to normal (or near-normal) functioning. (kidshealth.org)
- For example, some people only have a couple of bipolar episodes in their lifetime and are stable in between, while others have many episodes. (www.nhs.uk)
- Bipolar disorder in children, or pediatric bipolar disorder (PBD), is a mental disorder in children and adolescents that, like bipolar disorder (BD) in adults, is characterized by extreme changes in mood and behavior accompanying periods of depressed or irritable moods and periods of elevated moods called manic or hypomanic episodes. (wikipedia.org)
- In most people with bipolar disorder, there is no clear cause for the periods (episodes) of extreme happiness and high activity or energy (mania) or depression and low activity or energy (depression). (medlineplus.gov)
- A person who has four or more episodes of alternating between manic and depressive phases within a twelve-month period is said to have rapid cycling bipolar disorder. (encyclopedia.com)
- Most people with bipolar disorder are able to function normally between episodes once they get treatment. (encyclopedia.com)
- The treatment of bipolar disorder is focused on reducing the severity of manic and depressive episodes and helping sufferers lead an as-near-to-normal life as possible. (news-medical.net)
- Bipolar disorder , also called bipolar I disorder and previously called manic depression, is a condition that involves mood swings with at least one episode of mania and may also include repeated episodes of depression . (medicinenet.com)
- Bipolar disorder has a number of types, including bipolar I and bipolar II disorder based on the severity of symptoms, and may be described as mixed or rapid cycling based on the duration and frequency of episodes. (medicinenet.com)
- The adolescent with bipolar disorder is more likely to have depression and mixed episodes, with rapid changes in mood. (medicinenet.com)
- Major depressive episodes often alternate with manic episodes in bipolar disorder . (medicinenet.com)
- Suicide attempts are common in bipolar disorder, especially during depressive episodes. (psychcentral.com)
- Cyclothymia is a chronic but milder form of bipolar disorder, characterized by episodes of hypomania and depression that lasts for at least two years. (psychcentral.com)
- Rapid-cycling bipolar individuals experience four or more episodes of mania, depression, or both within one year. (psychcentral.com)
- Because the manic behavior and depressive episodes of bipolar disorder may mimic other mental illnesses, only a mental health professional can make an official diagnosis. (beliefnet.com)
- On average, someone with bipolar disorder may have up to three years of normal mood between episodes of mania or depression. (psychcentral.com)
- Bipolar disorder is recurrent, meaning that more than 90 percent of the individuals who have a single manic episode will go on to experience future episodes. (psychcentral.com)
- Roughly 70 percent of manic episodes in bipolar disorder occur immediately before or after a depressive episode. (psychcentral.com)
- Manic episodes can lead to family conflict or financial problems, especially when the person with bipolar disorder appears to behave erratically and irresponsibly without reason. (psychcentral.com)
- During severe manic or depressed episodes, some people with bipolar disorder may have symptoms that overwhelm their ability to deal with everyday life, and even reality. (psychcentral.com)
- Eric's symptoms qualify him for a diagnosis of bipolar disorder, which is characterized by episodes of full-blown mania or a less severe form called hypomania. (scientificamerican.com)
- A patient can be diagnosed with bipolar II if he or she has hypomania, the less severe form of mania, in which the manic episodes can be shorter-four days instead of a week-and do not impair functioning. (scientificamerican.com)
- Stimulant drugs such as Ritalin and Adderall, which are commonly used to treat ADHD, are not only ineffective for bipolar disorder but may worsen its symptoms or even trigger manic episodes. (scientificamerican.com)
- In fact, although treating bipolar disorder moods is critical, there is a convincing case supported by scientific studies that the prevention of further mood episodes should be the greatest goal. (webmd.com)
- In addition, people with bipolar disorder can have manic episodes that occur simultaneously with depressive symptoms, or vice versa. (webmd.com)
- And even though the exact cause of bipolar disorder is unknown there are a few factors that seems to be involved in causing and triggering bipolar episodes. (bartleby.com)
- December 13, 2011 Abstract Bipolar disorder, formerly known as manic depression, is a mood disorder in which a person experiences alternating episodes of both depression and mania. (bartleby.com)
- Depressive episodes in bipolar affective disorder often last for several months. (netdoctor.co.uk)
- Manic episodes in bipolar affective disorder often start abruptly, and usually last from between two weeks to several months. (netdoctor.co.uk)
- Bipolar I is identified by the length and severity of the manic and depressive episodes. (bartleby.com)
- This stems from the extreme mood changes of highs and lows that are categorized in this disorder, as the person is usually depressed but will go through manic episodes. (bartleby.com)
- Bipolar disorder consists of mood episodes. (yahoo.com)
- A phase III Efficacy and Safety of 3 week fixed dose asenapin treatment in pediatric acute manic or mixed episodes associated with Bipolar 1 Disorder in adolescents. (centerwatch.com)
- A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Once a Day, TAK-375 (Ramelteon) Tablet for Sublingual Administration (TAK-375SL Tablet) 0.1, 0.4, and 0.8 mg as an Adjunctive Therapy in the Treatment of Acute Depressive Episodes Associated with Bipolar 1 Disorder in Adult Subjects. (centerwatch.com)
- Researching the effectiveness of cariprazine for treatment of depressive episodes in patients with bipolar disorder. (centerwatch.com)
- Bipolar disorder is a mood disorder in which feelings, thoughts, behaviors, and perceptions are altered in the context of episodes of mania and depression . (medscape.com)
- Usually, patients who suffer from bipolar I disorder also experience depressive episodes. (reference.com)
- Individuals with bipolar disorder experience drastic depressive and manic mood episodes that alter normal energy and activity levels, sleep patterns and da. (reference.com)
- Bipolar patients usually experience severe mood swings and disruptions which cause them to switch between mania or extreme happiness and depressive episodes, sometimes even to the point of suicidal instances. (merlot.org)
- This study, which began in 1998 and concluded in September 2005, included a total of 4,360 participants with bipolar disorder who were followed long-term to determine which treatment(s), or combination of treatments are most effective for treating the episodes of depression and mania in bipolar disorder and for preventing recurrence. (healthyplace.com)
- Anticonvulsants are sometimes taken to treat or prevent the manic episodes associated with bipolar disorder. (psycom.net)
- Manic depressive or bipolar Mood Disorders are characterized by dramatic " mood swings " or episodes of Mania , Hypomania , or Major Depression . (behavenet.com)
- These drugs are considered a class of atypical antipsychotics that are FDA approved for the treatment of acute manic and mixed episodes associated with bipolar disorder. (foxnews.com)
- Bipolar I is considered the classic form of the illness, in which a person experiences recurrent episodes of mania and depression. (nih.gov)
- People with bipolar II experience a milder form of mania called hypomania that alternates with depressive episodes. (nih.gov)
- The peak age for manic or bipolar episodes among depression patients taking antidepressants was 26 to 35, the researchers reported. (newsmax.com)
- This research indicates a correlation of antidepressant treatment and manic episodes without reviewing preexisting risk factors of developing bipolar disorder, she explained. (newsmax.com)
- With bipolar disorder, people experience episodes of depression and episodes of mania. (cmha.ca)
- In a study at the University of Oxford in the United Kingdom, Allison G. Harvey, PhD, and colleagues in the department of experimental psychology determined that even between acute episodes of bipolar disorder, sleep problems were still documented in 70 percent of those who were experiencing a normal (euthymic) mood at the time. (athealth.com)
- Ziprasidone (Geodon) - approved to treat bipolar manic episodes and mixed episodes. (healthyplace.com)
- About 10% to 20% of people with bipolar disorder develop what is known as rapid cycling , with more than four episodes of mania and depression a year. (harvard.edu)
- People with bipolar mood disorder experience recurrent episodes of depressed and elated moods. (mental-health-matters.com)
- Some people with bipolar disorder do not experience depressive episodes-only the episodes of elation and excitement. (mental-health-matters.com)
- Many people with bipolar mood disorder experience depressive episodes. (mental-health-matters.com)
- Effective treatments are available for depressive and manic episodes of bipolar mood disorder. (mental-health-matters.com)
- Diagnosis of this Bipolar Disorder requires at least one Manic or Mixed episode, but there may be episodes of Hypomania or Major Depression as well. (behavenet.com)
- The majority of bipolar individuals experience alternating episodes of mania and depression. (encyclopedia.com)
- Bipolar I disorder is characterized by manic episodes, the "high" of the manic-depressive cycle. (encyclopedia.com)
- Bipolar II disorder is characterized by major depressive episodes alternating with episodes of hypomania, a milder form of mania. (encyclopedia.com)
- Treatment of manic and hypomanic episodes during pregnancy, prenatal maintenance pharmacotherapy for bipolar disorder, the teratogenic and postnatal risks of pharmacotherapy for bipolar disorder, and the general treatment of bipolar major depression are discussed separately. (uptodate.com)
- Roughly 20% of patients with mitochondrial disease also have bipolar disorder, a major psychiatric disease characterized by manic and depressive episodes. (scienceblog.com)
- Over eight years of follow-up, 44.4% of children with bipolar disorder displayed manic episodes after age 18, reported Barbara Geller, M.D., of Washington University in St. Louis here, and colleagues in the October issue of Archives of General Psychiatry . (medpagetoday.com)
- Some psychiatrists continue to be skeptical about the existence of childhood bipolar I disorder in part because it has a different presentation than in adults, with longer mania duration and often daily cycles during episodes. (medpagetoday.com)
- Patients with bipolar I disorder have had at least one episode of mania without any major depressive episodes whereas those with bipolar II disorder have had at least one episode of major depression without episodes of mania. (medpagetoday.com)
- Overall, 44.4% of the participants had bipolar episodes after they reached age 18 (mean 20.6 years). (medpagetoday.com)
- These findings were similar to those seen in previous studies of adults with bipolar I disorder, which showed a 20% rate of new episodes over two-years' follow-up, mood symptoms in 47.3% of weeks, and comorbid substance abuse disorders in a substantial proportion of patients (42.4% compared with 35.2% among those age 18 and over in Dr. Geller's study). (medpagetoday.com)
- Bipolar disorder is not a single disorder, but a category of mood disorders defined by the presence of one or more episodes of abnormally elevated mood, clinically referred to as mania . (bionity.com)
- The disorder has been subdivided into bipolar I , bipolar II and cyclothymia based on the type and severity of mood episodes experienced. (bionity.com)
- Bipolar disorder is often a cyclic illness where people periodically exhibit elevated (manic) and depressive episodes. (bionity.com)
- Rapid cycling , defined as having four or more episodes per year, is found in a significant fraction of patients with bipolar disorder. (bionity.com)
- Bipolar I disorder is defined as episodes of full mania alternating with episodes of major depression. (aafp.org)
- Bipolar II disorder is characterized by recurrent episodes of major depression and hypomania. (aafp.org)
- It is a type of bipolar disorder, and conforms to the classic concept of manic-depressive illness, which can include psychosis during mood episodes. (wikipedia.org)
- The essential feature of bipolar I disorder is a clinical course characterized by the occurrence of one or more manic episodes or mixed episodes (DSM-IV-TR, 2000). (wikipedia.org)
- Episodes of substance-induced mood disorder due to the direct effects of a medication, or other somatic treatments for depression, drug abuse, or toxin exposure, or of mood disorder due to a general medical condition need to be excluded before a diagnosis of bipolar I disorder can be made. (wikipedia.org)
- In addition, the episodes must not be better accounted for by schizoaffective disorder or superimposed on schizophrenia, schizophreniform disorder, delusional disorder, or a psychotic disorder not otherwise specified. (wikipedia.org)
- The hypomanic episodes associated with bipolar II disorder must last for at least four days. (wikipedia.org)
- Additionally, when compared to bipolar I disorder, type II presents more frequent depressive episodes and shorter intervals of well-being. (wikipedia.org)
- An estimated 2.9 percent of Americans have a diagnosis of bipolar disorder, and 83 percent of cases are classed as severe. (medicalnewstoday.com)
- The diagnosis of bipolar affective disorder, or manic-depressive illness (MDI), is based on the patient's history and clinical course. (medscape.com)
- A single manic episode is enough to make the diagnosis of Bipolar I Disorder. (yahoo.com)
- It is very, very rare to be able to control a true Diagnosis of BiPolar Disorder with 1 medication alone, whatever that medication might be. (dailystrength.org)
- Manic or mixed periods only need to last for seven days to allow for a diagnosis of bipolar disorder. (wikihow.com)
- Since Fisher had gone public with her diagnosis of bipolar I (the more serious form) four years earlier, Doan asked her the long-shot question: Would she pose for the cover and give a lengthy interview to a magazine that didn't exist yet? (usatoday.com)
- The diagnosis of bipolar disorder can be terrifying. (healthcentral.com)
- The incorrect diagnosis of bipolar or calling someone bipolar when there is a different set of symptoms disrupts lives, says Julie A. Fast. (healthcentral.com)
- There are a number of challenges that the diagnosis of bipolar spectrum disorder can pose, which is precisely why the following information is so essential to mental health professionals as well as patients and their families. (psycom.net)
- Cultural background influences how people understand and react to the symptoms and diagnosis of bipolar disorder. (rochester.edu)
- Diagnosis of Bipolar II Disorder and currently depressed for minimum of the last 8 weeks. (clinicaltrials.gov)
- Bipolar disorder, commonly known as manic depression, is a type of mental illness which is characterized by mood swings. (transparencymarketresearch.com)
- Bipolar disorder , previously known as manic depression , is a mental disorder that causes periods of depression and periods of abnormally elevated mood . (wikipedia.org)
- Bipolar disorder, formerly known as manic depression, is a condition that affects your moods, which can swing from one extreme to another. (www.nhs.uk)
- Also known as manic depression, bipolar disorder causes swings in mood, energy, and the ability to function throughout the day. (webmd.com)
- Bipolar affective disorder is also known as manic depression or bipolar depression. (netdoctor.co.uk)
- Bipolar affective disorder, also known as manic depression or bipolar depression, is a mood disorder. (netdoctor.co.uk)
- Bipolar and related disorders Justin Rodriguez Professor Hanselman Social Psychological Counseling Cumberland County College April 21, 2015 April 21, 2015 Abstract Bipolar Disorder (BD), also known as manic depression, is a mood disorder that is thought to affect some 5.5 million Americans, or 2.6 percent of the population (Treatment Advocacy Center). (bartleby.com)
- Bipolar disorder was previously known as manic depression, many people believe bipolar disorder is a controversial diagnosis, some labelling it madness rather than a medical condition. (bartleby.com)
- The age for the first onset of bipolar disorder -- once known as manic depression -- has plummeted from 32 to 19. (cnn.com)
- Previously known as manic depression, bipolar disorder was once thought to occur rarely in youth. (medscape.com)
- WebMD states that bipolar I disorder is also known as manic depression or manic-depressive disorder. (reference.com)
- Bipolar disorder, formerly known as manic depression, is a mood disorder that involves changes in mood and energy levels. (reference.com)
- One of these disorders is Bipolar disorder, also known as Manic-Depression. (merlot.org)
- Bipolar disorder, also known as manic depression, is a mental disorder that causes mood swings and other mental health issues. (wikihow.com)
- A moderately severe form of bipolar disorder, this classification is characterized by hypomania, a less intense form of mania, and longer periods of depression. (newsmax.com)
- Therefore, bipolar disorders are viewed as having a spectrum of symptoms that range from mild hypomania to the most extreme mania, which may include life-threatening behaviors, dysphoria, and psychotic features. (medscape.com)
- Patients who suffer from other subtypes of bipolar disorder may experience hypomania, a milder form of mania, but never experience the extreme symptoms of mania present in bipolar I patients. (reference.com)
- Patients with bipolar I disorder may also at times experience hypomania, a less severe manifestation of mania. (reference.com)
- However, hypomania is not exclusive to bipolar I patients. (reference.com)
- My bipolar hypomania, on the other hand, gives me the confidence to do things I'm not even qualified to do. (healthcentral.com)
- Diagnosis of this Bipolar Disorder requires neither a Manic nor a Mixed Episode, but does require at least one episode of hypomania in addition to an episode of Major Depression . (behavenet.com)
- See 'Bipolar disorder in pregnant women: Treatment of mania and hypomania' . (uptodate.com)
- The clinical presentations of this disorder are broad and include mania, hypomania and psychosis. (aafp.org)
- My md recommended this to me a couple years ago when I was complaining that neither he nor my pdoc was prescribing anything for my anxiety disorder and hypomania problems. (healthboards.com)
- pronounced "type two bipolar" or "bipolar type two" disorder) is a bipolar spectrum disorder (see also Bipolar disorder) characterized by at least one episode of hypomania and at least one episode of major depression. (wikipedia.org)
- Hypomania is the signature characteristic of Bipolar II disorder. (wikipedia.org)
- It is often the depressive phase that helps identify a person with bipolar disorder. (news-medical.net)
- During an emotional high or "mania," a person with bipolar disorder may feel excited, impulsive, euphoric, and full of energy. (healthline.com)
- In some cases, the person with bipolar disorder may be misdiagnosed as having a drug or alcohol problem. (encyclopedia.com)
- The emotions, thoughts, and behaviors of a person with bipolar disorder are often experienced as beyond one's control. (psychcentral.com)
- I have never been on medication for Bipolar Disorder. (medhelp.org)
- Bipolar disorder can be effectively treated with medication and psychotherapy. (psychcentral.com)
- Some natural remedies have been shown to work but none so far has a full effect as a mood stabilizer but as I've noted fish oil has been shown to have mood stabilization properties and the medication Lovaza which is an anti-cholesterol medication is in experimental use for bipolar. (medhelp.org)
- Whether bipolar pregnant women should stop taking medication depends on each individual case, expert says. (cnn.com)
- Should bipolar women discontinue their medication? (cnn.com)
- An effective treatment plan for bipolar I includes medication and psychotherapy. (bartleby.com)
- There's only 2 ways to treat BiPolar, medication and Therapy. (dailystrength.org)
- BiPolar Disorder is a NeuroChemical Disorder of the Brain and it takes several different types of medication to correct what our brain does not do correctly. (dailystrength.org)
- Since BiPolar is the combination of 2 mood disorder elements, the reality of 1 medication controlling both of them is as I said, very, very rare. (dailystrength.org)
- A phase 3 randomized double-blind placebo-controlled, parallel-group multicenter, fixed dose clinical trial evaluating efficacy, safety and tolerability of investigational medication in patients with Bipolar 1 depression. (centerwatch.com)
- The purpose of this study is to investigate safety and efficacy of investigational medication in the treatment of bipolar 1 depression. (centerwatch.com)
- The term bipolar disorders encompasses a number of diagnoses including bipolar I disorder, bipolar II disorder, cyclothymic disorder, substance/medication-induced bipolar and related disorder, bipolar and related disorder due to another medical condition, other specified bipolar and related disorder, and unspecified bipolar and related disorder as classified by the Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5). (springer.com)
- Early identification of medication nonresponders would be extremely helpful in the treatment of bipolar disorder. (medscape.com)
- Genome-wide association studies (GWASs) potentially can help to identify whether lithium is likely to be effective or if other medication such as atypical antipsychotic medication or antiepileptic medication will be more likely effective in bipolar disorder to stabilize mood. (medscape.com)
- Unlike in many psychiatric disorders, there are bigger chances of controlling and managing manic depression through psychotherapy and medication. (merlot.org)
- Geodon is a relatively new medication for bipolar disorder and schizophrenia. (dailystrength.org)
- Bipolar disorder needs strong medication in order to get stabilization, and therefore, any herbal supplement that would truly be effective, would also need to be very strong, and would need to be under a Dr.s supervision. (dailystrength.org)
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- Galynker and Ablow both said that bipolar medication is most effective when used in conjunction with therapy. (foxnews.com)
- The researchers found that many were receiving medication treatment considered "inappropriate" for bipolar disorder, e.g., they were taking an antidepressant or other psychotropic medication in the absence of a mood stabilizing medication such as lithium, valproate, or carbamazepine. (nih.gov)
- Such a high rate of inappropriate medication use among people with bipolar spectrum disorder is a concern," said Dr. Merikangas. (nih.gov)
- Major depression is one of the most common mental disorders in the United States, According to the U.S. Centers for Disease Control and Prevention, about one in 10 Americans aged 12 years and over takes antidepressant medication. (newsmax.com)
- If you have been diagnosed with Bipolar Disorder, then medication and therapy may become important. (mental-health-matters.com)
- Anxiety is common among individuals with bipolar disorder and can exacerbate the negative symptoms, resulting in suicidal ideation, poorer quality of life, more severely impaired functioning, and even nonresponse to medication. (goodtherapy.org)
- Children with bipolar who exhibit symptoms of anxiety alone may be prescribed medication that can increase their depressive states, causing their conditions to deteriorate rather than improve. (goodtherapy.org)
- Other mental health issues such as anxiety disorders and substance use disorder are commonly associated with bipolar disorder. (wikipedia.org)
- For example, kids who have bipolar disorder may experience particularly rapid mood changes and may have some of the other mood-related symptoms listed below, such as irritability and high levels of anxiety. (kidshealth.org)
- I agree that bipolar, schizophrenia (and family,) depression, and anxiety disorders are all physical disorders that effect the brain. (medhelp.org)
- Subjects with bipolar disorder have significant cognitive and functional deficits, even when they are euthymic," lead author Dan Iosifescu, MD, director, Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai, New York City, told Medscape Medical News . (medscape.com)
- Obsessive-compulsive disorder, or OCD, is an anxiety disorder in which sufferers become obsessed with things like personal safety, grooming and cleanliness. (reference.com)
- High occurrence of mood and anxiety disorders among older adults: the national comorbidity survey replication. (springer.com)
- How do doctors measure and diagnose conditions from anxiety to personality disorders, especially when there is more than one condition involved? (qualityhealth.com)
- According to the study, eating disorders, anxiety disorders and alcohol problems are also more common in those with bipolar, as is metabolic syndrome. (indiatimes.com)
- Up to 97 percent of those who had some type of bipolar illness said they had coexisting psychiatric conditions, such as anxiety, depression or substance abuse disorders, and many were in treatment for those conditions rather than bipolar disorder. (nih.gov)
- Merikangas and colleagues speculate that as people seek treatment for anxiety, depression or substance abuse disorders, their doctors, especially if they are not mental health specialists, may not be detecting an underlying bipolar condition in their patients. (nih.gov)
- But I have to say that while the bipolar symptoms and their consequences have been more dramatic, it's the anxiety that has been the biggest culprit in keeping me from doing the things I want to do. (healthcentral.com)
- She wrote for HealthCentral as a patient expert for Anxiety and Bipolar Disorder. (healthcentral.com)
- Any mental health professionals who have dealt with those with bipolar spectrum disorder will certainly agree that there are a number of patients who are suffering from anxiety, depression, and other symptoms that don't exactly fall within the DSM classifications. (psycom.net)
- Once a Bipolar II mood disorder with disturbed rhythms has begun, it tends to be self-perpetuating, since depression and anxiety are likely to disrupt 24-hour rhythms further. (athealth.com)
- These normal-mood patients with bipolar disorder expressed dysfunctional beliefs and behaviors regarding sleep that were similar to those suffering from insomnia, such as high levels of anxiety, fear about poor sleep, low daytime activity level, and a tendency to misperceive sleep. (athealth.com)
- If you've been diagnosed with ADHD, odds are you also exhibit symptoms of anxiety, a mood disorder, sensory. (additudemag.com)
- Does Anxiety Predict Bipolar Disorder in Children? (goodtherapy.org)
- Understanding the correlates between anxiety and bipolar in young people can significantly benefit their treatment. (goodtherapy.org)
- In an effort to better comprehend how bipolar and anxiety are related in children and to determine if anxiety predicts the onset of bipolar in teens in children, Aswin Ratheesh of the Department of Psychiatry at the National Institute of Mental Health and Neuro Sciences in Bangalore, Karnataka, analyzed the medical records of 46 teens diagnosed with bipolar. (goodtherapy.org)
- The study revealed that nearly all of the teens (90%) had struggled with anxiety prior to developing bipolar disorder. (goodtherapy.org)
- Ratheesh also discovered that the teens with anxiety were more likely to have developed bipolar disorder at a younger age than the teens without anxiety. (goodtherapy.org)
- The teens with anxiety and bipolar displayed a weaker level of functioning and poorer emotional, physical, and social quality of life than those with bipolar alone. (goodtherapy.org)
- Ratheesh realizes that this study does not demonstrate that anxiety causes bipolar but emphasizes the need for clinicians to address anxiety as an isolated issue when treating teens with bipolar. (goodtherapy.org)
- Ratheesh added, "More importantly, treatment studies of bipolar disorder should specifically examine the impact of various comorbid disorders including anxiety disorders on treatment response and outcome. (goodtherapy.org)
- Having one of these issues to deal with would be enough by itself, but having to deal with both bipolar and anxiety would be another whole can of worms! (goodtherapy.org)
- I am assuming that there are different treatment modes for those suffering from anxiety and bipolar together than there is when one suffers from only one of the disorders. (goodtherapy.org)
- Frequently associated comorbid conditions include substance abuse and anxiety disorders. (aafp.org)
- For Bipolar I Disorder 296.40 Most Recent Episode Hypomanic and 296.4x Most Recent Episode Manic, the proposed revision includes the following specifiers: with Psychotic Features, with Mixed Features, with Catatonic Features, with Rapid Cycling, with Anxiety (mild to severe), with Suicide Risk Severity, with Seasonal Pattern, and with Postpartum Onset. (wikipedia.org)
- Bipolar disorder affects approximately 1% of the global population. (wikipedia.org)
- Bipolar disorder affects both men and women. (kidshealth.org)
- Bipolar affects about 2 percent of the U.S. population. (healthline.com)
- Bipolar disorder affects around 60 million people around the world. (healthline.com)
- Bipolar disorder affects all ages, genders, and ethnicities, and usually has its onset in late adolescence or young adulthood. (webmd.com)
- Bipolar disorder affects 1 in 100 people in the world. (bartleby.com)
- Bipolar disorder is not an uncommon illness and, according to the National Institute of Mental Health (NIMH), it affects 2.6 percent of U.S. adults today. (mercola.com)
- Bipolar affective disorder affects both men and women, and people of all ages. (netdoctor.co.uk)
- Bipolar disorder affects the ability to function and carry out daily tasks. (reference.com)
- Bipolar disorder is a potentially serious mental health issue that affects about 1 in 50 people. (wikihow.com)
- Bipolar disorder is known to result in very obvious mood changes to those it affects. (wikihow.com)
- Bipolar disorder affects equal numbers of men and women. (hopkinsmedicine.org)
- Bipolar disorder affects approximately 5.7 million adult Americans, or about 2.6 percent of the U.S. population age 18 and older, according to the National Institute of Mental Health. (foxnews.com)
- Bipolar disorder is another mental illness that affects mood. (cmha.ca)
- Bipolar mood disorder affects two people in every hundred of the Australian population. (mental-health-matters.com)
- While the disorder affects people differently, individuals with bipolar disorder tend to be much more outgoing and daring than individuals without bipolar disorder. (bionity.com)
- The number of individuals with bipolar disorder who commit suicide is 60 times higher than that of the general population. (medicinenet.com)
- However, individuals with bipolar disorder experience severe mood swings that impair their daily life and negatively affect their relationships. (psychcentral.com)
- Researchers believe that some neurotransmitters, including serotonin and dopamine, don't function properly in individuals with bipolar disorder. (psychcentral.com)
- The brains of individuals with bipolar disorder appear somewhat physically different from those without the condition. (newsmax.com)
- Individuals with bipolar disorder struggle with many issues, including poor treatment outcome and overall decreased functioning. (goodtherapy.org)
- Bipolar disorder goes by many names: manic depression, manic-depressive disorder, manic-depressive illness, bipolar mood disorder, and bipolar affective disorder are medical terms for the same condition. (kidshealth.org)
- Commonly used assessment tools include the K-SADS (Kiddie Schedule for Affective Disorders and Schizophrenia), the Diagnostic Interview Schedule for Children (DISC), and the Child Mania Rating Scale (CMRS). (wikipedia.org)
- Bipolar disorder, also called bipolar I disorder and formerly called manic depression, is a mental illness , specifically one of the affective (mood) disorders. (medicinenet.com)
- Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. (medscape.com)
- The first genomewide interaction and locus-heterogeneity linkage scan in bipolar affective disorder: strong evidence of epistatic effects between loci on chromosomes 2q and 6q. (medscape.com)
- People with bipolar affective disorder experience marked mood swings, each of which may last for several weeks or longer, unlike simple mood swings which most people experience. (netdoctor.co.uk)
- It's estimated that about 1 to 2 per cent of the UK population suffer from bipolar affective disorder at some point in their lives, which is similar to the prevalence in other countries around the world. (netdoctor.co.uk)
- Bipolar affective disorder is thought to be due to an imbalance of chemical transmitters in the brain. (netdoctor.co.uk)
- The illness often runs in families, and it's thought that differences in people's genetic make-up can make them more prone to develop bipolar affective disorder. (netdoctor.co.uk)
- A manic episode of bipolar affective disorder is a period of a week or longer during which a person feels abnormally good, high, excited, hyper or irritable. (netdoctor.co.uk)
- Go to Bipolar Affective Disorder for complete information on this topic. (medscape.com)
- It has sometimes been called manic depression or even bipolar affective disorder. (edhelper.com)
- Because two thirds of bipolar patients have a family history of affective or emotional disorders, researchers have searched for a genetic link to the disorder. (encyclopedia.com)
- (CNN) - At least three neuropsychiatric disorders -- autism, schizophrenia and bipolar disorder -- appear to share similar patterns of gene activity, a new study suggests. (click2houston.com)
- The new study found that four sets of genes were less active in the neurons of people diagnosed with autism, schizophrenia and bipolar disorder. (click2houston.com)
- A 2003 study found that schizophrenia and bipolar disorder could have similar genetic causes that arise from certain problems with genes associated with myelin development in the central nervous system. (encyclopedia.com)
- But children and adults can have bipolar disorder too. (medlineplus.gov)
- In the United States alone, it's estimated that more than 17.4 million adults have a depressive disorder each year. (kidshealth.org)
- Recent research suggests that kids and teens with bipolar disorder don't always have the same behavioral patterns that adults with bipolar disorder do. (kidshealth.org)
- Bipolar disorder is fairly common and one in every 100 adults will be diagnosed with the condition at some point in their life. (www.nhs.uk)
- Main discussion is centered on whether what is called BD in children refers to the same disorder than when diagnosing adults, and the related question on whether adults' criteria for diagnosis are useful and accurate when applied to children. (wikipedia.org)
- The mixed state is more common in children or adolescents with the disorder than in adults. (encyclopedia.com)
- Approximately 2.6 percent of American adults have bipolar disorder (formerly called manic depression and manic depressive disorder), according to the National Institute of Mental Health. (psychcentral.com)
- By 2003, the researchers reported, the number of office visits resulting in a bipolar diagnosis in these youths had risen from 25 per 100,000 people to 1,003 per 100,000 people, a rate almost as high as that for adults. (scientificamerican.com)
- The inclusion of this milder form of the disorder enabled many more children (as well as adults) to qualify for a bipolar diagnosis. (scientificamerican.com)
- VA/DoD clinical practice guideline for management of bipolar disorder in adults. (medscape.com)
- Bipolar disorder in older adults: a critical review. (springer.com)
- However, approximately 20% of adults with bipolar disorder had symptoms beginning in adolescence. (medscape.com)
- NIMH researcher Kathleen Merikangas, Ph.D. and colleagues identified prevalence rates of three subtypes of bipolar spectrum disorder among adults. (nih.gov)
- In the study, patterns of neural activation during a reward task predicted the severity of the mania symptom in young adults who have not yet developed the disorder. (elsevier.com)
- Given that emerging manic symptoms predispose to bipolar disorders, these findings can provide neural biomarkers to aid early identification of bipolar disorder risk in young adults," said first author Leticia de Oliveira, PhD, Federal Fluminense University, Brazil. (elsevier.com)
- Bipolar disorder: The management of bipolar disorder in adults, children and adolescents, in primary and secondary care. (uptodate.com)
- Explain to interested patients that the study followed children diagnosed with bipolar disorder to see whether they would recover without further symptoms as adults. (medpagetoday.com)
- Cyclothymia: Cyclothymia is a mild form of bipolar disorder in which the person's highs and lows are not as extreme as in the first two types. (encyclopedia.com)
- The primary characteristic distinguishing bipolar I disorder from other subtypes of bipolar disorder such as bipolar II disorder and cyclothymia is the presence of mania. (reference.com)
- Bipolar disorder can be characterized into bipolar I, bipolar II, and cyclothymia. (businesswire.com)
- The Diagnostic and Statistical Manual of Mental Disorders, fourth edition ( DSM-IV ), the diagnostic standard for mental health professionals in the United States , defines four separate categories of bipolar disorder: bipolar I, bipolar II, cyclothymia, and bipolar not-otherwise-specified (NOS). (encyclopedia.com)
- One third of patients with cyclothymia develop bipolar I or II disorder later in life. (encyclopedia.com)
- Bipolar NOS is a category for bipolar states that do not clearly fit into the bipolar I, II, or cyclothymia diagnoses. (encyclopedia.com)
- Bipolar disorder is a mental health disorder that was previously called manic depressive psychosis or manic depression. (news-medical.net)
- Psychosis and Bipolar Disorder 2 I just rose out of a crying moment where I was hearing, seeing and feeling that I will never overcome my present circumstances. (selfgrowth.com)
- Even more alarming, bipolar women are 100 times more likely than other women to experience postpartum psychosis, a severe mood disorder that, at its very worst, can result in infanticide. (cnn.com)
- Bipolar disorder may also feature psychosis (delusions and/or hallucinations). (yahoo.com)
- Polygenic investigations indicate that this disorder is phenotypically separate (with or without psychosis) from schizoaffective disorders and schizophrenia. (medscape.com)
- Also, the study was observational, and 'we did not demonstrate a causal association between antidepressants and mania and bipolar disorder,' said lead researcher Dr. Rashmi Patel, of the department of psychosis studies at King's College London's Institute of Psychiatry, Psychology and Neuroscience. (newsmax.com)
- REM sleep abnormalities have been implicated by doctors in a variety of psychiatric disorders, including depression, posttraumatic stress disorder, some forms of schizophrenia, and other disorders in which psychosis occurs. (athealth.com)
- Read about bipolar with psychosis . (healthyplace.com)
- Heritability of bipolar spectrum disorders. (medscape.com)
- Cade's Disease" and beyond: misdiagnosis, antidepressant use, and a proposed definition for bipolar spectrum disorder. (springer.com)
- Bipolar disorder represents not a single disease, but a spectrum of disorders. (qualityhealth.com)
- A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder. (nih.gov)
- The findings support international studies suggesting that, given its multi-dimensional nature, bipolar disorder may be better characterized as a spectrum disorder. (nih.gov)
- Because bipolar spectrum disorder commonly coexists with other illnesses, it is likely underrecognized, and therefore, undertreated. (nih.gov)
- We need better screening tools and procedures for identifying bipolar spectrum disorder, and work with clinicians to help them better spot these bipolar symptoms," concluded Dr. Merikangas. (nih.gov)
- Patterns of brain activation during reward anticipation may help identify people most at risk for developing bipolar spectrum disorders (BPSD), according to a study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging , published by Elsevier. (elsevier.com)
- Adapted from the Goldberg Bipolar Spectrum Screening questionnaire (c. 1993) designed to screen for the possibility of bipolar spectrum disorders in individuals 18 or older who have already experienced at least one episode of depression. (additudemag.com)
- These three conditions together affect approximately three to four percent of the population, although recent research and clinical observations seem to indicate that bipolar spectrum disorders may impact a larger percentage of the population to a lesser degree. (psycom.net)
- Continued efforts are being made to properly subtype the bipolar spectrum, but those patients who have sub-threshold bipolar disorder are currently diagnosed with bipolar disorder NOS, or not otherwise specified. (psycom.net)
- Today, the leader in the realm of bipolar disorder and subtyping is undoubtedly Hagop Akiskal , a clinical researcher with great respect for Kraepelin and his classification of the bipolar spectrum. (psycom.net)
- Until proper sub-typing of bipolar spectrum disorders is accepted and used across the board, psychiatrists who are aware of this none-too-rare subgroup are required to go outside of the DSM to diagnose these individuals. (psycom.net)
- It has been suggested that Bipolar spectrum be merged into this article or section. (bionity.com)
- pronounced "type one bipolar disorder") is a bipolar spectrum disorder characterized by the occurrence of at least one manic or mixed episode. (wikipedia.org)
- Diagnosed with bipolar disorder, she is careful to take her medications and to keep her depressive moods under control. (encyclopedia.com)
- Treatment of bipolar disorder with medications tends to relieve already existing symptoms of mania or depression and prevent symptoms from returning. (medicinenet.com)
- When treating bipolar disorder sufferers who are pregnant or nursing , health care professionals take great care to balance the need to maintain the person's stable mood and behavior while minimizing the risks that medications used to treat this disorder may present. (medicinenet.com)
- Bipolar medications aren't considered as risky during pregnancy as they once were, but they aren't exactly harmless either. (cnn.com)
- Early recognition of bipolar warning signs and seeing your doctor regularly can allow you to monitor your mood and medications and keep illness from escalating. (webmd.com)
- Bipolar disorder is treated with medications to stabilize mood. (webmd.com)
- And just to be clear, its not one med, BiPolar patients take a Cocktail of Medications. (dailystrength.org)
- Bipolar disorder is treated successfully with medications such as mood stabilizers, antipsychotics and antidepressants, according to the National Institute of Mental Health. (reference.com)
- Are there any major differences between Tegretol and other medications used to treat bipolar disorder? (psycom.net)
- Medications for depression, bipolar disorder, schizophrenia, and other mental health disorders can be lifesaving for people who need them. (qualityhealth.com)
- But a new understanding of the disorder, a new treatment philosophy and a second-generation of medications that are safer and more effective have paved the way for bipolar sufferers to finally seek the help they need. (foxnews.com)
- I would say the two main things that have change from the standpoint of psychological treatment are the dramatic change to psycho-social treatment that is family-based and the second-generation of antipsychotic medications that are now being used as maintenance drugs," said Dr. Igor Galynker, director of the Bipolar Family Treatment Center at Beth Israel Medical Center in New York City. (foxnews.com)
- that airs on Oct. 30, Rene Russo reveals something about her that none of us knew: She has bipolar disorder and is treating it regularly with medications. (glamour.com)
- In this case, however, it is difficult to say that these medications cause bipolar disorder, since several risk factors related to underlying bipolar disorder were not assessed in this study, said Baxi, who was not involved with the study. (newsmax.com)
- For patients who are concerned about this risk of conversion to bipolar disorder, the results of this study should encourage a discussion with your doctor regarding the benefits of the antidepressant and your risk factors for developing bipolar disorder before making any changes in medications,' she said. (newsmax.com)
- In addition, certain medications used to treat bipolar disorder may disrupt the sleep-wake cycle. (athealth.com)
- This remains one of the few first-generation (aka typical) antipsychotic medications still used today for the treatment of bipolar (mania) . (healthyplace.com)
- Medications are commonly used to treat pregnant patients, including those with bipolar major depression [ 1 ]. (uptodate.com)
- Bipolar disorder is usually treated with medications and/or therapy or counseling. (bionity.com)
- Some patients have a mixed state, in which the high energy of the manic phase of the disorder is combined with the blue mood of the depressed phase. (encyclopedia.com)
- The disorder is not caused by one gene, however, because identical twins of patients diagnosed with the disorder do not always develop it. (encyclopedia.com)
- Given current NHS policies and financial pressures to maximise treatment in the community rather than in hospital, it seems likely that over the next few years in Britain there may be more courses for suitable bipolar patients to become expert patients. (bmj.com)
- Talking therapy, cognitive behavioural therapy, family and group therapy, and counselling are all useful approaches for treating patients with bipolar disorder. (news-medical.net)
- Ironically, treating depressed bipolar patients with antidepressants can trigger a manic episode in some patients. (psychcentral.com)
- In a randomized, controlled, parallel-arm clinical trial of adjuvant memantine vs placebo in euthymic patients with bipolar disorder, memantine improved several cognitive domains and also demonstrated increased hippocampus neuronal viability on imaging scans of the brain. (medscape.com)
- Fifty-five percent of the patients had type I bipolar disorder, and 45% had bipolar II disorder. (medscape.com)
- Some patients are diagnosed with clinical depression earlier in life and then the diagnosis will be changed to bipolar disorder if they have a manic episode, sometimes years later. (netdoctor.co.uk)
- I've worked in the Mental Health Field with BiPolar Patients. (dailystrength.org)
- This study is designed to prospectively confirm the efficacy of a fixed-dose regimen of cariprazine 1.5 mg/day or 3 mg/day compared to placebo for treatment of the depressive episode in patients with bipolar I disorder. (centerwatch.com)
- Late-life bipolar disorders generally refer to the onset of disorder in patients older than 60 years, though the cutoff age can be variable. (springer.com)
- Practice guideline for the treatment of patients with bipolar disorder. (springer.com)
- Likewise the people who want to study ERVs and schizophrenia/bipolar disorder/MS/ALS cant just take a slice of brain out of their patients and get to work. (scienceblogs.com)
- They also made an interesting observation- Patients with schizophrenic and bipolar disorder had 1) fewer copies of related ERVs in their genome than healthy controls, and 2) little differences between the sequences that were active in diseased vs healthy. (scienceblogs.com)
- With the help of their friends and family, bipolar patients can live normally and minimize their mood swing attacks. (merlot.org)
- People with bipolar disorder had higher levels of saturated fats in their diets, and the research also found associations between levels of certain fat molecules in the blood of patients and their mood or level of symptoms. (indiatimes.com)
- This study shows how the powerful combination of computational image analysis tools and functionally targeted task fMRI (in this case reward processing) can provide insights into the neural systems underlying symptoms that may indicate liability to mania, in a young, non-bipolar transdiagnostic group of psychiatric patients," said Cameron Carter, MD, Editor of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging . (elsevier.com)
- Some commonly used antidepressants may increase certain patients' risk of developing mania or bipolar disorder, a large study suggests. (newsmax.com)
- However, many patients who developed mania or bipolar symptoms likely had underlying bipolar disorder or a predisposition because of family history or other factors, the researchers believe. (newsmax.com)
- Nearly 1,000 patients were diagnosed with bipolar disorder or mania during the follow-up period of roughly four years. (newsmax.com)
- Patel agreed and said better ways of identifying depression patients who may be at risk of developing bipolar disorder need to be developed. (newsmax.com)
- These patients suffer from a sub-threshold bipolar disorder and are often less willing to receive medical therapies such as antidepressants. (psycom.net)
- Dr. Harvey concluded that even when the bipolar patients were not in a depressive, hypomanic, or manic mood state, they still had difficulty maintaining good sleep. (athealth.com)
- Working with the families of schizophrenia and bipolar patients, as well as addressing the stigma associated with mental illness is especially important for Asian American patients, even more than mainstream and other American ethnic groups. (springer.com)
- 2010). Higher prevalence of bipolar I disorder among Asian and Latino compared to Caucasian patients receiving treatment. (springer.com)
- Mixed states, where both manic or hypomanic symptoms and depressive symptoms occur at the same time, also occur frequently with bipolar I patients (for example, depression with the racing thoughts of mania). (encyclopedia.com)
- Patients with bipolar depression tend to have extremely low energy, retarded mental and physical processes, and more profound fatigue (for example, hypersomnia, a sleep disorder marked by a need for excessive sleep or sleepiness when awake) than unipolar depressives. (encyclopedia.com)
- A phenomenon known as rapid cycling occurs in up to 20 percent of bipolar I and II patients. (encyclopedia.com)
- In a survey of bipolar patients conducted by the National Depressive and Manic Depressive Association (MDMDA), one half of respondents reported visiting three or more professionals before receiving a correct diagnosis, and over one third reported waiting ten years or more before they were correctly diagnosed. (encyclopedia.com)
- Another possible biological cause under investigation is the presence of an excessive calcium build-up in the cells of bipolar patients. (encyclopedia.com)
- Over one-half of patients diagnosed with bipolar disorder have a history of substance abuse, which may be an issue in adolescent patients. (encyclopedia.com)
- This topic discusses treatment of pregnant patients with bipolar major depression. (uptodate.com)
- American Psychiatric Association Practice Guideline for the Treatment of Patients With Bipolar Disorder Second Edition http://psychiatryonline.org/guidelines.aspx (Accessed on December 19, 2011). (uptodate.com)
- Mitochondria are the vital organelles that deliver energy to all cells and mitochondrial damage has been found, for example, in brain imaging of bipolar patients and in post-mortem brains. (scienceblog.com)
- The study started by identifying ANT1 mutations in patients with bipolar disorder. (scienceblog.com)
- This study is an 8-week evaluation of an investigational drug for treating depression in bipolar patients. (clinicaltrials.gov)
- More and more, researchers are finding that childhood trauma is common among bipolar patients, with as many as 50 percent reporting incidents of childhood trauma. (prezi.com)
- Bipolar I disorder is typically diagnosed when patients are in their early 20s. (aafp.org)
- Lithium is the mainstay in the management of bipolar disorder but it has a narrow therapeutic range and typically requires monitoring Anticonvulsants, such as sodium valproate, carbamazepine or lamotrigine Antipsychotics, such as quetiapine, risperidone, olanzapine or aripiprazole Electroconvulsive therapy, a psychiatric treatment in which seizures are electrically induced in anesthetized patients for therapeutic effect Some antidepressants, like venlafaxine, have been found to precipitate a manic episode. (wikipedia.org)
- BMD has several subtypes, the most common of which are Bipolar I and Bipolar II, which is often misdiagnosed as depression. (additudemag.com)
- Previous studies of families have already shown that there are multiple genetic subtypes of the disorder, but progress in identifying the exact genes responsible has been slow because groups of families inherit different susceptibility genes. (innovations-report.com)
- There are several proposed revisions to occur in the diagnostic criteria of Bipolar I Disorder and its subtypes. (wikipedia.org)
- It is likely that you will always have some degree or form of bipolar disorder. (familydoctor.org)
- A mild form of bipolar disorder that may be somewhat disruptive in a person's life. (newsmax.com)
- Symptoms of this severe form of bipolar disorder generally have a disruptive effect on a person's life, making it difficult to work and maintain relationships. (newsmax.com)
- The causes of bipolar disorder aren't always clear. (medlineplus.gov)
- The causes of bipolar disorder are not completely understood, although the disorder is known to run in families. (encyclopedia.com)
- There are no single definitive causes of Bipolar Disorder, but research has shown that a complex. (mental-health-matters.com)
- People with bipolar disorder often face problems with social stigma. (wikipedia.org)
- That works out to about 1 out of every 7 people, so there's a good chance that you or someone you know is dealing with a depressive disorder. (kidshealth.org)
- Because brain function is involved, the ways people with bipolar disorder think, act, and feel are all affected. (kidshealth.org)
- It can be incredibly frustrating if other people act as though someone with bipolar disorder should just 'snap out of it,' as if a person who is sick can become well simply by wanting to. (kidshealth.org)
- Some people with bipolar disorder turn to alcohol and drugs because they feel temporarily better when they're high. (kidshealth.org)
- But using alcohol and drugs can have disastrous results for people with bipolar disorder. (kidshealth.org)
- Unlike simple mood swings, each extreme episode of bipolar disorder can last for several weeks (or even longer), and some people may not experience a "normal" mood very often. (www.nhs.uk)
- The pattern of mood swings in bipolar disorder varies widely between people. (www.nhs.uk)
- Most people with mood swings do not have bipolar disorder. (familydoctor.org)
- People who have bipolar disorder alternate between mania and depression. (familydoctor.org)
- People who have bipolar disorder seek care when they are depressed more often than when they're manic. (familydoctor.org)
- Some people who have bipolar disorder don't want to get treatment or don't think they need it. (familydoctor.org)
- People with bipolar disorder may have trouble managing everyday life tasks, at school or work, or maintaining relationships. (healthline.com)
- The exact cause is not known, but it occurs more often in relatives of people with bipolar disorder. (medlineplus.gov)
- People with bipolar disorder are at high risk for suicide . (medlineplus.gov)
- Most people develop symptoms of the disorder in the late teen years or early twenties, but some begin to show signs of the disorder in childhood and others may develop symptoms in their later years. (encyclopedia.com)
- People with bipolar disorder have a 25-50 percent risk of attempting suicide at some point in adult life. (encyclopedia.com)
- The mood swings involved in bipolar disorder are far more severe, debilitating, and incapacitating than those experienced by most people. (medicalnewstoday.com)
- Some studies have shown that people with bipolar disorder may have enhanced creativity . (medicalnewstoday.com)
- Bipolar disorder afflicts up to 4 million people in the United States and is the fifth leading cause of disability worldwide. (medicinenet.com)
- The suicide rate for people with bipolar disorder is 60 times higher than in the general public. (medicinenet.com)
- Talk therapy ( psychotherapy ) is an important part of helping people with bipolar disorder achieve the highest level of functioning possible. (medicinenet.com)
- There seems to be no increase in involvement with violent crime for people with bipolar disorder compared to the general population except for those bipolar disorder sufferers that also suffer from an alcohol or other substance use disorder. (medicinenet.com)
- Yes bipolar is clinically complex given that people with bipolar are at the same time as they experience mania are physically sped up as well and can have psychomoter agitation, increased libido and a decrease in sleep which can have a physical effect. (medhelp.org)
- Most people with bipolar disorder are of the slow cycling type - they experience long periods of being up ("high" or manic phase) and of being down ("low" or depressive phase). (psychcentral.com)
- There is no cure for bipolar disorder, but through behavior therapy and the right combination of mood stabilizers and other bipolar medicines, most people with bipolar disorder can live normal, productive lives. (webmd.com)
- At least fifteen percent of people with bipolar disorder commit suicide. (bartleby.com)
- Some people with cyclothymic disorder later develop full-blown bipolar disorder. (bartleby.com)
- In contrast, Bipolar Disorder is a medical condition in which people have mood swings out of proportion, or totally unrelated, to things going on in their lives. (bartleby.com)
- Many people with bipolar I take combination medicine treatment. (bartleby.com)
- According to statistics, there are at least 9.3 million people in the United States who have been diagnosed as having bipolar disorder. (lulu.com)
- Clinical trial testing new treatment for people with bipolar depression. (centerwatch.com)
- The study, published last week in the journal Science, looked at gene products -- otherwise known as messenger RNA -- in over 800 human brains donated from people with psychiatric illnesses including autism, schizophrenia, bipolar disorder, depression and alcoholism, as well as control brains from people without the illnesses. (click2houston.com)
- Previous studies have identified genes shared among people with particular psychiatric disorders. (click2houston.com)
- There is no cure for bipolar disorder, but treatment works well for many people. (hopkinsmedicine.org)
- People with psychological disorders are often misunderstood by society at large. (merlot.org)
- People who suffer from this mood disorder may seem crazy to "normal" people because. (merlot.org)
- This book intends to help people with bipolar disorder understand their condition better and disprove the notion that theirs are hopeless cases. (merlot.org)
- Carrie's significance in encouraging people who are bipolar to get over their shame, and her kindness to others in the community, were among the most striking things I learned in researching her life for my forthcoming book, "Carrie Fisher: A Life On the Edge. (usatoday.com)
- People with bipolar illness can have productive lives like anybody else, once they're in treatment and compliant with treatment. (go.com)
- This magnet therapy has helped some people with bipolar disorder with few reported side-effects. (healthyplace.com)
- People with bipolar disorder often suffer from extreme highs, causing agitation, elation, mania and bouts of sleeplessness, as well as periods of lows, marked by depression and suicidal thoughts. (foxnews.com)
- Some people with bipolar disorder also suffer psychotic symptoms during the manic phase where they are delusional or hear voices or see visions. (foxnews.com)
- The researchers found that migraine headaches are three and a half times more common among people with bipolar disorder than those without. (indiatimes.com)
- More people with bipolar disorder have a history of childhood trauma than those without the condition, it is associated with changes in self-control and attention. (indiatimes.com)
- What most people don't understand, is that bipolar doesn't just affect you, but the ones you love as well. (change.org)
- A comprehensive overview of bipolar disorder including symptoms and diagnosis, managing relationships, research trends, and strategies for people with bipolar and their loves ones on how to manage the disorder. (healthcentral.com)
- People who are more physically active throughout the day have more perceived energy and a more positive mood, especially those with bipolar disorder. (healthcentral.com)
- Here are nine famous people living with bipolar disorder, each telling a story of emotional resilience. (healthcentral.com)
- Julie Fast is an author, columnist, and CEU certified coach who trains health care professionals and parents and partners of people with bipolar disorder. (healthcentral.com)
- Still, the findings highlight the need to consider risk factors for bipolar disorder in people treated for major depression, Patel said. (newsmax.com)
- The study authors noted that people with undiagnosed bipolar disorder may be more likely to seek treatment when in the depressive stage of the illness, which could help explain the link between antidepressants and later bipolar behavior. (newsmax.com)
- The collaboration, led by Professor Hugh Gurling at UCL and Professor Ole Mors at the University of Aarhus, first looked at bipolar cases in families living in the UK and in Denmark, and then at large numbers of unrelated people with bipolar disorder. (innovations-report.com)
- Using techniques such as animal models will help us to fully understand the mechanisms behind this gene and explore how we might be able to intervene in these mechanisms, to help people with the disorder. (innovations-report.com)
- Around one in every 200 people in the UK develops bipolar and other related mood disorders. (innovations-report.com)
- People with bipolar disorder may also experience extreme mood highs, overactivity, increased libido, sleeplessness and grandiose delusions. (innovations-report.com)
- Many people wonder if they have Bipolar Disorder. (infobarrel.com)
- Depression and bipolar disorder are two mental illnesses that change the way people feel and make it hard for them to go about their daily routine. (cmha.ca)
- Depression and bipolar disorder can isolate people from others, and isolation can add to mood problems. (cmha.ca)
- Olanzapine (Zyprexa) - approved for people age 13 and over with bipolar disorder type 1 . (healthyplace.com)
- People with bipolar disorder differ from those with other depressive disorders in that their moods swing from depression to mania, often with periods of relatively normal mood between the two extremes. (harvard.edu)
- Close relatives of people suffering from bipolar disorder are much more likely to develop it, or some other form of depression, than the general population. (harvard.edu)
- People who take amphetamines or corticosteroid drugs or people with overactive thyroid glands have symptoms similar to those of people with the manic phase of bipolar disorder. (harvard.edu)
- Some people have bipolar disorder for months, if not years, before it is diagnosed. (harvard.edu)
- Studies reveal that people with rheumatoid arthritis are at a greater risk of developing bipolar disorder than the general population. (psychcentral.com)
- Specifics vary across studies, as does conjecture about the cause, but an analysis of several research filings state that people with RA are nearly 3 times more likely to have bipolar disorder. (psychcentral.com)
- And any trip to a psych ward or the patio around the entrance of a building where a support group is meeting will quickly show that many people with bipolar disorder smoke. (psychcentral.com)
- 68.8% of people with bipolar disorder currently smoke, and 82.5% of people with BP have smoked at some point during their lives. (psychcentral.com)
- Many people do not realize that there are actually two types of bipolar disorder. (mental-health-matters.com)
- The disorder is also found in a large number of people involved in the arts. (bionity.com)
- In addition, many people who suffer from Bipolar II have periods of normal affect. (wikipedia.org)
- This mental illness is termed as bipolar disorder due to these different moods or two poles of mood. (transparencymarketresearch.com)
- Individuals with a family history of bipolar disorder are most likely to develop the illness. (transparencymarketresearch.com)
- Government initiatives such as launch of Bipolar Disorder Phenome Database, funded by the National Institute of Mental Health (NIMH), provide complete information regarding signs and symptoms of the illness. (transparencymarketresearch.com)
- Bipolar disorder is a serious mental illness. (medlineplus.gov)
- Bipolar disorder is a mental illness that causes extreme mood swings. (familydoctor.org)
- Bipolar disorder is a mental illness marked by extreme shifts in mood, from high to low. (healthline.com)
- In my opinion it is to few parents (family-members) of the ones suffering from the mental illness Bipolar Disorder, (Manic Depressive Disorder) who talks/write about the subject. (amazonaws.com)
- Bipolar disorder (or manic depression) is a mental illness characterized by depression, mania, and severe mood swings. (medicinenet.com)
- In this volume, the one in use today, the illness is subdivided into bipolar I, essentially equivalent to the DSM-III version of this malady, and bipolar II, which has less stringent diagnostic criteria. (scientificamerican.com)
- Bipolar disorder, is also known as manic-depressive illness, this is a brain disorder that causes unusual mood swings, energy levels are either up or down and your ability to function a normal everyday life would be a challenge to these individuals with this mental illness. (bartleby.com)
- Bipolar disorder is also called manic-depressive illness. (bartleby.com)
- Known originally as manic depression, Bipolar Disorder is a mental illness that creates mood swings that affect an individual's behavior and emotions, which can result in a lot of pain. (bartleby.com)
- Feeling depressed or down can be a normal reaction to events in our lives, but in a depressive illness that occurs as part of bipolar disorder, the depressive feelings will be worse, they will go on for longer and they will make it harder to deal with day-to-day problems. (netdoctor.co.uk)
- Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks (National Institutes of Health, Bipolar Disorder). (bartleby.com)
- Treatment of Bipolar Disorder Bipolar disorder is a chronic mental illness that requires lifelong management to be maintained. (bartleby.com)
- For starters, bipolar disorder (formerly known as manic-depressive illness) is defined as "a mental health disorder where a person experiences changes in their mood, energy, activity levels, and thought patterns" (Berry). (yahoo.com)
- Bipolar I disorder , the "classic" form of the illness, is defined by at least one manic or mixed episode. (yahoo.com)
- Common symptoms of mental illness vary depending on the disorder, but include feelings of sadness, difficulty concentrating, extreme worry, and substantial. (reference.com)
- Bipolar disorder, a ferocious mental illness, seems to be showing up in kids at an increasing rate. (cnn.com)
- Even at "Star Wars" events, she spoke of her illness and "made extra time, long after she was supposed to leave, talking to fans who were also bipolar," said David Zentz, a nuclear worker and "Star Wars" fanatic who saw her at more than three dozen events over the years. (usatoday.com)
- Mental illness is agonizing, and bipolar disorder has its own form of agony. (usatoday.com)
- Bipolar disorder, also known as manic depressive illness, is a mental illness characterized by mood swings between the two psychological pulls of depression and euphoria. (go.com)
- It can start at any time in a person's life and it's a lifelong illness," Dr. Igor Galynker, director of the Family Center for Bipolar Disorder at Beth Israel Medical Center told ABC News OnCall . (go.com)
- The median age of onset for bipolar disorder is 25 years, but the illness can start in early childhood or as late as the 40s and 50s. (foxnews.com)
- But regardless of type, the illness takes a huge toll," said NIMH Director Thomas R. Insel, M.D. "The survey's findings reiterate the need for a more refined understanding of bipolar symptoms, so we can better target treatment. (nih.gov)
- Bipolar disorder is also known as manic-depressive illness. (newstimes.com)
- I heard it should be possible with a bipolar illness. (healthboards.com)
- Bipolar disorder is a serious mental illness that is characterized by extreme mood swings, abrupt changes in energy levels, and distorted decision making. (additudemag.com)
- Bipolar disorder is the new name for what was called manic depressive illness. (mental-health-matters.com)
- Studies on close relations, identical twins and adopted children whose natural parents have bipolar mood disorder strongly suggest that the illness is genetically transmitted, and that children of parents with bipolar mood disorder have a greater risk of developing the disorder. (mental-health-matters.com)
- How To Find Out If Your Child Has A Mental Disorder And How To Cope Identifying mental illness in. (mental-health-matters.com)
- Bipolar disorder is the name of a group of mood disorders characterized by alternation between periods of high energy, known as mania, and periods of depression. (encyclopedia.com)
- Bipolar disorder is not just a single disorder, but a category of mood disorders marked by periods of abnormally high energy and euphoria, often accompanied by bouts of clinical depression. (dailystrength.org)
- Mood disorders such as bipolar disorder are often linked to an imbalance in these brain chemicals. (newsmax.com)
- Mood Disorders: Are They Caused by Vitamin Deficiencies? (qualityhealth.com)
- And insufficient intake of certain vitamins have been linked to mood disorders. (qualityhealth.com)
- There are two common types of mood disorders: depression and bipolar disorder. (qualityhealth.com)
- Mood disorders are more prevalent than you may think, affecting as many as 44 million Americans. (qualityhealth.com)
- Researchers find more evidence that creativity and mood disorders are linked. (qualityhealth.com)
- A type of counselling called cognitive-behavioural therapy (or 'CBT') is common for mood disorders. (cmha.ca)
- An irregular living schedule can aggravate mood disorders. (athealth.com)
- To doctors who are trained in mood disorders, ADHD symptoms can look like bipolar disorder. (additudemag.com)
- During a manic phase of bipolar disorder, you may feel very happy and have lots of energy, ambitious plans and ideas. (www.nhs.uk)
- Recognize the symptoms of the manic phase of bipolar disorder. (wikihow.com)
- Dr. Keith Ablow, a psychiatrist and FOX News contributor, said the drugs, which were developed to treat schizophrenia and other psychotic illnesses, block what is believed to be an excessive amount of dopamine produced during the manic phase of bipolar disorder. (foxnews.com)
- Bipolar disorder II (BPII): The person has had at least one episode of depression and at least one hypomanic episode. (encyclopedia.com)
- This is four times more common than Bipolar I, and is identified by having hypomanic symptoms (less severe manic symptoms). (mercola.com)
- Type II bipolar disorder (BPII) is diagnosed on the basis of at least 1 hypomanic episode. (medscape.com)
- Be aware that bipolar disorder may be misdiagnosed because there is another type of bipolar that includes a hypomanic state. (wikihow.com)
- If you have Bipolar II Disorder, you will experience at least one Hypomanic Episode and one Major Depressive Episode. (infobarrel.com)
- To be diagnosed with Bipolar II Disorder, you will experience both a Major Depressive Episode and a Hypomanic Episode, one after the other. (infobarrel.com)
- I got diagnosed with hypomanic bipolar back in January. (healthboards.com)
- The difference with bipolar II disorder is that the latter requires that the individual must never have experienced a full manic or mixed-manic episode - only less severe hypomanic episode(s). (wikipedia.org)
- There have also been proposed revisions to part B of the diagnostic criteria for a Hypomanic Episode, which is used to diagnose For Bipolar I Disorder 296.40, Most Recent Episode Hypomanic. (wikipedia.org)
- The report includes a detailed analysis of the pipeline molecules under investigation within the defined data collection period to treat bipolar disorder. (businesswire.com)
- The implication of this research is that emerging therapies for the underlying mitochondrial dysfunction could one day treat bipolar disorder more successfully than today's variable serotonin-targeting drugs. (scienceblog.com)
- Outcome studies show that compared with unipolar depression, bipolar disorder causes more work disability and overall poorer outcome 15 years after an index hospitalized manic episode even when mania is in remission for at least 1 year. (medscape.com)
- In later editions of the DSM, this morphed into what was known as the unipolar/bipolar dichotomy. (psycom.net)
- Bipolar depression may be difficult to distinguish from a unipolar major depressive episode. (encyclopedia.com)
- Finally, bipolar II is associated with a greater risk of suicidal thoughts and behaviors than bipolar I or unipolar depression. (wikipedia.org)
- Bipolar disorder often starts in a person's late teen or early adult years. (medlineplus.gov)
- Depressive disorders affect the way a person's brain functions. (kidshealth.org)
- Bipolar disorder takes a heavy toll on a young person's educational development, employment, and relationships. (encyclopedia.com)
- However, if left untreated, bipolar disorder can seriously affect nearly every aspect of a person's life. (psychcentral.com)
- Bipolar disorder , sometimes called manic depression , is a mental health disorder that is distinguished by dramatic changes in a person's mood and energy, from the elated highs of mania to the lows of depression . (webmd.com)
- In a related disorder called cyclothymic disorder (sometimes called Bipolar III), a person's mood alternates between mild depression and mild mania. (bartleby.com)
- Bipolar disorder is a psychiatric disorder that is episodic and chronic and can lead to significant impairment in a person's life. (springer.com)
- The revelation that the seemingly unshakable actress Catherine Zeta-Jones has been diagnosed with bipolar II disorder illustrates the hallmarks of the disease: it can strike at any time in a person's life and is often brought on by prolonged stressed. (go.com)
- A short circuit between a person's biological clock and the 24-hour day causes this sleep disorder. (athealth.com)
- The global bipolar disorder market is segmented based on types of bipolar disorder, drug class, mechanism of action, and geography. (transparencymarketresearch.com)
- Rapid-cycling bipolar disorder causes faster changes in mood than other types of bipolar disorder. (healthline.com)
- What Are the Different Types of Bipolar Disorder? (psychcentral.com)
- There are different types of Bipolar and everyone's symptoms are different. (dailystrength.org)
- Bowden C, Singh V. Long-term management of bipolar disorder. (medscape.com)
- 69. Management of Bipolar Disorder Working Group. (medscape.com)
- Make your management of bipolar disorder comprehensive. (qualityhealth.com)
- Management of bipolar disorder during pregnancy and the postpartum period. (uptodate.com)
- However, in the case of bipolar disorder, moods may last for weeks or months at a time with a normal mood being the exception. (news-medical.net)
- Bipolar disorder ("manic depression ") is a mental disorder that is characterized by constantly changing moods between depression and mania . (psychcentral.com)
- The session may include help accepting the diagnosis, education about bipolar moods, ways to identify warning signs, and intervention strategies to manage stress . (webmd.com)
- How long these moods last and how strong they are will depend on how strong your bipolar disorder is. (wikihow.com)
- However, moods and behaviors that change without connection to outside events and last for long periods of time can be indicative of bipolar disorder. (wikihow.com)
- However, research has shown that the first episode of bipolar disorder is occurring earlier: It often shows up in adolescence, and even children can have the disorder. (kidshealth.org)
- Usually, the first recognized episode of bipolar disorder is a manic episode. (psychcentral.com)
- While bipolar disorder cannot be prevented, it's important to be aware of early warning signs of an impending episode of bipolar depression or bipolar mania. (webmd.com)
- You must also meet at least five of the listed criteria in the Diagnostic and Statistical Manual of Mental Disorders. (healthline.com)
- In 1980 the American Psychiatric Association came out with a radically revised third edition of its diagnostic bible, the Diagnostic and Statistical Manual of Mental Disorders ( DSM-III ). (scientificamerican.com)
- Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. (medscape.com)
- Signs and symptoms - Your symptoms will be evaluated and compared with the criteria for bipolar and related disorders, as stated in the Diagnostic and Statistical Manual of Mental Disorders. (mercola.com)
- What Are Some of the Most Common Mental Disorders? (reference.com)
- Diagnostic and statistical manual of mental disorders. (springer.com)
- Diagnostic and statistical manual of mental disorders, fourth edition symptoms of mania: which one(s) result(s) more often from right than left hemisphere lesions? (springer.com)
- analyzed data from the National Comorbidity Survey Replication (NCS-R), a nationwide survey of mental disorders among 9,282 Americans ages 18 and older. (nih.gov)
- 2000). Diagnostic and statistical manual of mental disorders DSM-IV-TR Fourth Edition (4th ed. (springer.com)
- Diagnosis was by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria with at least one cardinal symptom --elation or grandiosity -- to avoid overlap with attention-deficit hyperactivity disorder (ADHD). (medpagetoday.com)
- The criteria for major depressive episode and manic episode, as described in the Diagnostic and Statistical Manual of Mental Disorders , 4th ed. (aafp.org)
- The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was released in May 2013. (wikipedia.org)
- 6 Here are some of the warning signs of this disorder, which can be divided under depression and mania. (mercola.com)
- The researchers believe poor sleep plays a key role in bipolar disorder, with links found to severity of depression and mania in female, but not male, participants with the condition. (indiatimes.com)
- There are several available treatments that can help you manage your bipolar disorder. (healthline.com)
- The purpose of this study is to measure the efficacy of fixed dose treatments of cariprazine for the treatment of bipolar depression. (centerwatch.com)
- Learning the symptoms of this disorder can help you work with your trusted health care provider and get the best care and treatments you might need. (wikihow.com)
- Insights gleaned from the study could help drive the development of treatments for a number of psychiatric disorders, according to Arking. (click2houston.com)
- Research into new treatments for bipolar disorder include magnetic therapy, rTMS, and the Step-BD program to determine the best treatment practices for bipolar disorder. (healthyplace.com)
- We hope our discovery will eventually lead to new treatments for depression and bipolar disorder, including possible preventive strategies, for example with drugs or even through nutritional intervention. (innovations-report.com)
- At one time, it was believed that antidepressants could be used for treating bipolar disorder, but over time their use proved ineffective and potentially dangerous, said Galynker. (foxnews.com)
- The fact that antidepressants for bipolar depression were not working or harmful was devastating," he said. (foxnews.com)
- But not only do antidepressants not improve bipolar symptoms, they may increase the incidence of mania or cause mixed mania in bipolar individuals. (foxnews.com)
- We found that antidepressants were widely prescribed and associated with a small increased risk in developing mania and bipolar disorder,' said Patel. (newsmax.com)
- However, antidepressants may not be the best option for bipolar disorder. (cmha.ca)
- It's an emotional disorder that is marked by periods of extreme elation and depression,' he says. (glamour.com)
- Bipolar disorder, once known as manic-depressive disorder or manic depression, is a form of depression in which periods of deep depression alternate with periods of hyperactivity and uncontrolled elation (mania). (harvard.edu)
- Bipolar disorder is characterized by variations in mood, from elation and/or irritability to depression. (aafp.org)
- Increase in awareness about diagnosis and treatment of bipolar disorder and unmet needs in the treatment of the disorder are the major drivers for the growth of the market. (transparencymarketresearch.com)
- North America dominates the global bipolar disorder market due to increased awareness and larger availability of treatment options. (transparencymarketresearch.com)
- Bipolar Treatment: Are Bipolar I and Bipolar II Treated Differently? (medlineplus.gov)
- It's thought using a combination of different treatment methods is the best way to control bipolar disorder. (www.nhs.uk)
- With proper treatment, individuals with bipolar can lead fulfilling, productive lives. (psychcentral.com)
- Learn what factors prompt doctors to advise treatment for bipolar disorder. (beliefnet.com)
- Identifying the first episode of mania or depression and receiving early treatment is essential to managing bipolar disorder. (psychcentral.com)
- The following chapter outlines an overview of the various bipolar disorders including the diagnosis, assessment, and evidence-based treatment of the bipolar disorders. (springer.com)
- [ 3 ] Randomized controlled trials of combination mood stabilizer treatment (more than one mood stabilizer such as atypicals + lithium + valproate) suggest this may improve outcome by increasing the time to relapse for any mood episode compared with monotherapy as maintenance therapy for Bipolar I. (medscape.com)
- The Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) is a large, national research program to determine the best treatment practices for bipolar disorder. (healthyplace.com)
- What are Some of the Bipolar Disorder Treatment Challenges? (healthyplace.com)
- Take our 2-minute Bipolar quiz to see if you or a loved one may benefit from further diagnosis and treatment. (psycom.net)
- Bipolar disorder is a lifelong condition that can be managed if you get professional treatment and support. (wikihow.com)
- An early diagnosis and treatment plan can also greatly improve your day to day life with this disorder. (wikihow.com)
- However, if you feel that your mood easily fluctuates day to day or week to week, speak to your doctor about whether or not you have bipolar disorder and learn what your treatment options are. (wikihow.com)
- For example, you may say to those close to you, "I acknowledge that I have bipolar disorder and that I need help" or "I realize that I have manic depression and want to seek treatment. (wikihow.com)
- Be proactive about getting treatment for bipolar disorder. (wikihow.com)
- A good treatment plan can help you live better with bipolar disorder. (wikihow.com)
- At Beth Israel's Bipolar Family Treatment Center, Galynker and staff use a family-based approach to treating bipolar disorder. (foxnews.com)
- Bipolar disorder is a long-lasting condition that can be with regular treatment plans. (businesswire.com)
- Most respondents with bipolar disorder reported receiving treatment. (nih.gov)
- Nearly everyone who had bipolar I or II (89 to 95 percent) received some type of treatment, while 69 percent of those with BD-NOS were getting treatment. (nih.gov)
- However, not everyone received treatment considered optimal for bipolar disorder. (nih.gov)
- These include a family history of bipolar disorder, a prior depressive episode with psychotic symptoms, depression at a young age, or depression that doesn't respond to treatment, he said. (newsmax.com)
- Take our 2-minute Bipolar quiz to see if you may benefit from further diagnosis and treatment. (psycom.net)
- Approved for bipolar mania, mixed state and maintenance treatment. (healthyplace.com)
- Quetiapine (Seroquel) - the only antipsychotic approved for the treatment of bipolar depression. (healthyplace.com)
- FDA-approved for bipolar mania and mixed state treatment. (healthyplace.com)
- One additional drug, Symbax is approved for the treatment of bipolar depression and is an olanzapine/fluoxetine (Prozac) combination. (healthyplace.com)
- Psychoeducation - Helps the patient and their family understand bipolar disorder and seek out he best treatment and recognize warning signs. (prezi.com)
- It's just so important to see if it's necessary to tweak or even change treatment methods when there are two disorders that coexist.Because when you're thinking you are curing one of them you could just be making the other worse! (goodtherapy.org)
- Although a few still hold this view, the general opinion of the psychiatric community has drastically shifted over the past 30 years, a period in which diagnoses of the disorder in kids have skyrocketed. (scientificamerican.com)
- According to the psychiatric community, I have bipolar 1 with ultra rapid cycling, but I don't take meds anymore. (selfgrowth.com)
- the reference manual for psychiatric disorders. (nih.gov)
- Those with bipolar I or II were more commonly treated by psychiatric specialists, while those with BD-NOS were more commonly treated by general medical professionals. (nih.gov)
- The American Psychiatric Association's Diagnostic and Statistical Manual 4th Edition (DSM-IV) classifies Bipolar Disorder in two different categories, Bipolar Disorder I and Bipolar Disorder II. (infobarrel.com)
- A person with this disorder will have periods of feeling joyful, energized, and excited (called mania). (hopkinsmedicine.org)
- Zeta-Jones is said to have been diagnosed with bipolar II, which is a form of the disorder which is characterized by longer low periods. (go.com)
- Substance abuse disorders (which have high co-morbidity with BP-II) and periods of mixed depression may also make it more difficult to accurately identify BP-II. (wikipedia.org)
- Bipolar I is considered the classic type of bipolar disorder. (psychcentral.com)
- Many critics have raised concerns that this manual's loosened criteria have misclassified many children as bipolar II who had features too mild to really qualify them for any type of bipolar disorder-or who suffer from entirely different ailments. (scientificamerican.com)
- The exact cause of bipolar disorder is unknown, although it's believed a number of things can trigger an episode. (www.nhs.uk)
- The exact cause of bipolar disorder is unknown. (medicinenet.com)
- The cause of bipolar disorder is not known. (hopkinsmedicine.org)
- The cause of bipolar disorder had not as of 2004 been clearly defined. (encyclopedia.com)