Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.Cocaine: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.Compulsive Behavior: The behavior of performing an act persistently and repetitively without it leading to reward or pleasure. The act is usually a small, circumscribed behavior, almost ritualistic, yet not pathologically disturbing. Examples of compulsive behavior include twirling of hair, checking something constantly, not wanting pennies in change, straightening tilted pictures, etc.Reward: An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure.Cocaine-Related Disorders: Disorders related or resulting from use of cocaine.Cholinergic Antagonists: Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists.Obsessive Behavior: Persistent, unwanted idea or impulse which is considered normal when it does not markedly interfere with mental processes or emotional adjustment.Crack Cocaine: The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.Consummatory Behavior: An act which constitutes the termination of a given instinctive behavior pattern or sequence.Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.Muscarinic Antagonists: Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.Hydromorphone: An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.Drug Information Services: Services providing pharmaceutic and therapeutic drug information and consultation.Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)Polyethylenes: Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.Polyethylene: A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.Glycols: A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)Ethylene Glycols: An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.Cathartics: Agents that are used to stimulate evacuation of the bowels.Administration, Rectal: The insertion of drugs into the rectum, usually for confused or incompetent patients, like children, infants, and the very old or comatose.Heat Stroke: A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.Administration, Cutaneous: The application of suitable drug dosage forms to the skin for either local or systemic effects.Suppositories: Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.Parasympatholytics: Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.Baths: The immersion or washing of the body or any of its parts in water or other medium for cleansing or medical treatment. It includes bathing for personal hygiene as well as for medical purposes with the addition of therapeutic agents, such as alkalines, antiseptics, oil, etc.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.

Effect of psychotropic drugs on caudate spindle in cats. (1/18)

To ascertain whether neuroleptics act on the caudate nucleus itself, the effects of these compounds as well as other centrally acting drugs were examined in relation to caudate spindle and EEG arousal responses (sciatic nerve stimulation) in gallamine-immobilized cats. Haloperidol and chlorpromazine enhanced the caudate spindle at a dose which had no effect on the EEG arousal response. On the other hand, clozapine and a higher dose of chlorpromazine enhanced the caudate spindle, but depressed the arousal response. High frequency stimulation of the sciatic nerve suppressed the caudate spindle. Pentobarbital, biperiden and diazepam, while depressing the arousal response, caused an enhancement of the caudate spindle. Imipramine at a low dose had no effect on either response, whereas at a high dose this drug enhanced the caudate spindle with concomitant depression of the arousal response. From these results, it may be concluded that the enhancing action on the caudate spindle induced by haloperidol and a low dose of chlorpromazine is due to an increase in susceptibility of the caudate nucleus itself. In addition, it is suggested that depression of the activating system is involved in an appearance of the caudate spindle.  (+info)

Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in human plasma. (2/18)

Estimation of xenobiotic kinetics in humans frequently relies upon extrapolation from experimental data generated in animals. In an accompanying paper, we have presented a unique, generic, physiologically based pharmacokinetic model and described its application to the prediction of rat plasma pharmacokinetics from in vitro data alone. Here we demonstrate the application of the same model, parameterized for human physiology, to the estimation of plasma pharmacokinetics in humans and report a comparative evaluation against some recently published predictive methods that involve scaling from in vivo animal data. The model was parameterized through an optimization process, using a training set of in vivo data taken from the literature, and validated using a separate test set of published in vivo data. On average, the vertical divergence of the predicted plasma concentrations from the observed data, on a semilog concentration-time plot, was 0.47 log unit. For the training set, more than 80% of the predicted values of a standardized measure of the area under the concentration-time curve were within 3-fold of the observed values; over 70% of the test set predictions were within the same margin. Furthermore, in terms of predicting human clearance for the test set, the model was found to match or exceed the performance of three published interspecies scaling methods, all of which showed a distinct bias toward overprediction. We conclude that the generic physiologically based pharmacokinetic model, as a means of integrating readily determined in vitro and/or in silico data, is potentially a powerful, cost-effective tool for predicting human xenobiotic kinetics in drug discovery and risk assessment.  (+info)

The effects of baclofen and cholinergic drugs on upbeat and downbeat nystagmus. (3/18)

The GABAergic drug baclofen and the cholinergic drug physostigmine were administered to patients with upbeat and downbeat nystagmus. Baclofen (orally, 5 mg three times daily) reduced nystagmus slow phase velocity and distressing oscillopsia by 25-75% in four out of five patients (two upbeat nystagmus; two downbeat nystagmus). Physostigmine (1 mg single intravenous injection) increased nystagmus in five additional patients with downbeat (1) or positional downbeat nystagmus (4) for a duration of 15-20 minutes. The different interactions of baclofen and physostigmine on neurotransmission subserving vertical vestibulo-ocular reflex could account for these effects. The response to baclofen appears to be a GABA-B-ergic effect with augmentation of the physiological inhibitory influence of the vestibulo-cerebellum on the vestibular nuclei. Similarly baclofen has an inhibitory effect on the velocity storage mechanism. Cholinergic action may cause the increment of nystagmus by physostigmine.  (+info)

The use and potential abuse of anticholinergic antiparkinson drugs in Norway: a pharmacoepidemiological study. (4/18)

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Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. (5/18)

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A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment. (6/18)

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Hemiparkinsonism-hemiatrophy syndrome. (7/18)

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Polypharmacy in the treatment of schizophrenic patients in three University Centers in the Federation of Bosnia and Herzegovina (F/BH). (8/18)

BACKGROUND: Polypharmacy in psychiatry is becoming the rule rather than the exception. Using more drugs at same time usually occurs where single drugs are considered insufficiently effective. SUBJECTS AND METHODS: The sample consisted of 216 patients: 85 from Sarajevo, and 44 and 87 respectively from Mostar and Tuzla. All schizophrenic patients who were hospitalised in three University Centers of F/BiH (Sarajevo, Tuzla, Mostar) on a particular day are included in the study. This included patients of both sexes (131 (60.65%) males and 85 females (39.35%)), 20-60 ages, who were on antipsychotic treatment with an established diagnosis of schizophrenia by the treating psychiatrist. The research was performed in the year 2004. The census of patients was conducted simultaneously in all three Centers, using a questionnaire in which all routine prescribed antipsychotics were registered, as the common method of the administration, and the doses as well saving as data for other medications that were simultaneously prescribed to the patients that day. RESULTS: Within the total sample the most frequently applied classical antipsychotics were haloperidol, promazine and from the group of new antipsychotics clozapine. The most frequently used other medications were biperidine and diazepam. The administration of all medication was followed through recording of individual doses, daily doses and frequency of administration. There are statistically significant differences regarding the frequency of biperidine use between the centers (p=0.008). CONCLUSION: In three University Clinical Centers of the Federation of Bosnia and Herzegovina (Sarajevo, Tuzla and Mostar), the applied rule is that more drugs in the treatment of schizophrenic psychosis and doing polypharmacy is the inevitable approach to treatment. The concept behind the polypharmacy is based on the fact that antipsychotic drugs do not cover all the symptoms of schizophrenic psychosis, and that additional medications may correct iatrogenic side effects caused by antipsychotic drugs. It is expected that the new atypical antipsychotics will treat much broader symptoms of psychosis and will not cause extrapyramidal side effects, as do the typical antipsychotics.  (+info)

*Biperiden

... is in the anticholinergic family of medication. Biperiden was approved for medical use in the United States in 1959. ... Additionally, biperiden may decrease maternal milk production. It is therefore recommended that biperiden is not used during ... Biperiden does also act as FIASMA (functional inhibitor of acid sphingomyelinase). Biperiden was synthesized by the German ... Biperiden may be abused due to a short acting mood-elevating and euphoriant effect. The normal sleep architecture may be ...

*Bridged compounds

... biperiden; and methenamine. The following are texts and other sources covering the title subject. Well-regarded intermediate ...

*Cycrimine

Biperiden Procyclidine Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, page ...

*Bornaprine

Hohagen, F; Lis, S; Riemann, D; Krieger, S; Meyer, C; Montero, R. F.; Grunze, H; Berger, M (1994). "Influence of biperiden and ... "Neuere pharmakologische Aspekte zu den zentralen Anticholinergika Biperiden und". Das Parkinson-Syndrom (in German). pp. 277-87 ...

*Delirium

Similar anticholinergic drugs such as biperiden and scopolamine have also produced delirium-like effects. These models, along ...

*Methyl vinyl ketone

The resulting norbornene derivative is an intermediate in the synthesis of the anticholinergic drug biperiden. Via its ...

*C21H29NO

The molecular formula C21H29NO (molar mass: 311.46 g/mol) may refer to: Alphamethadol Betamethadol Biperiden Dimepheptanol ...

*Anticholinergic

Examples of common anticholinergics: Antimuscarinic agents Atropine Benztropine (Cogentin) Biperiden Chlorpheniramine (Chlor- ...

*Nerve agent

Some synthetic anticholinergics, such as biperiden, may counteract the central symptoms of nerve agent poisoning better than ...

*Trihexyphenidyl

Other dyskinesias Huntington's chorea Spasmodic torticollis Dystonia Biperiden (bicyclic ring) Cycrimine (cyclopentanyl instead ...

*List of MeSH codes (D03)

... biperiden MeSH D03.383.621.135 --- cisapride MeSH D03.383.621.147 --- clopamide MeSH D03.383.621.160 --- cyproheptadine MeSH ...

*Schedule H

... salts Bacampicillin Benserazide Hydrochloride Betahistine Dihydrochloride Bethanidine Sulphate Bezafibrate Biclotymol Biperiden ...

*List of drugs: Bi-Bo

... biperiden (INN) biphasic insulin injection (INN) Biphetamine Biphetap biricodar (INN) biriperone (INN) Bisac-Evac bisacodyl ( ...

*FIASMA

Alverine Amiodarone Amitriptyline Amlodipine Aprindine Astemizole AY-9944 Benzatropine Bepridil Biperiden Camylofin Carvedilol ...

*WHO Model List of Essential Medicines

... α Anastrozoleα Bicalutamideα Dexamethasoneα Hydrocortisoneα Leuprorelinα Methylprednisoloneα Prednisoloneα Tamoxifenα Biperiden ...

*List of MeSH codes (D02)

... biperiden MeSH D02.455.426.392 --- hydrocarbons, alicyclic MeSH D02.455.426.392.368 --- cycloparaffins MeSH D02.455.426.392. ...

*ATC code N04

N04AA01 Trihexyphenidyl N04AA02 Biperiden N04AA03 Metixene N04AA04 Procyclidine N04AA05 Profenamine N04AA08 Dexetimide N04AA09 ...
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Looking for online definition of Miller and Modigliani's irrelevance proposition in the Medical Dictionary? Miller and Modigliani's irrelevance proposition explanation free. What is Miller and Modigliani's irrelevance proposition? Meaning of Miller and Modigliani's irrelevance proposition medical term. What does Miller and Modigliani's irrelevance proposition mean?
100% Export Oriented Unit of Antiparkinson Drugs - Ciplactin, Daxid, Cefadroxil and Trivastal LA Tablet offered by B S Medicine & Food Private Limited, Mumbai, Maharashtra
Market Research Future adds new report of "Global Nano therapy Market Research Report- Forecast To 2027" it contains Company information, geographical data and Table of Content. Nanotechnology offers the likelihood to improve tranquilize dissolvability and quality, drag out medicine half-lives in plasma, limit off target effects, and accumulate drugs at a goal site. Nanotechnology is described as submicron evaluated nuclear devices or nanoparticles pervasively running from 5 to 500 nm in one measurement. Liberal past investigation effort has realized procedures to combine supportive administrators into biocompatible Nano gadgets including polymer nanoparticles, liposomes, micelle structures, inorganic nanoparticles, nanotubes, and dendrites. The Global Nano Therapy Market is required to develop at great CAGR.. Get a Sample Report @ https://www.marketresearchfuture.com/sample_request/924 .. Competitive Analysis: Some of the key players for the Global Nano Therapy are: Washington University center ...
A trusted name in imaging services since 1995, University Center Imaging (UCI) provides the highest level of patient care and testing services available in a full service diagnostic imaging facility. Using state of the art equipment, UCI is able to reduce scan times and provide diagnostic procedures that arent offered in most outpatient imaging facilities. This gold standard in outpatient radiology performance has fostered a high level of confidence throughout the area for physicians and their patients.
University Centre Shrewsbury (UCS) staff, students and partners are kick-starting groundbreaking research and developing solutions to improve the health of people with heart, lung and circulation diseases.. Global company Renew Health is funding a project led by John Buckley, Professor of Applied Exercise Science at UCS and its Centre for Active Living. The investment is part of Renews Global Billions in Change movement which is tackling pressing problems around the world in the areas of water purification, accessible energy and preventative healthcare.. The initiative at UCS is investigating the benefits of External Counter Pulsation (ECP) Therapy, a treatment proven to improve peoples cardiovascular health. This includes people with heart disease who have not been able to have by-pass surgery or coronary angioplasty (stents) - a procedure used to widen blocked or narrowed arteries in the heart.. During Renew ECP treatment, inflatable cuffs (similar to blood pressure cuffs) are wrapped around ...
Cecil K. and Philip Drinker Professor of Environmental PhysiologyDirector, Center for Children and Environmental HealthHarvard University Center for the EnvironmentHarvard School of Public Health
Find info concerning University Center MI laboratory jobs. Seek out accredited healthcare programs for the best training. Given a brief hospital internship or prior work experience, you can expect a great return on your medical education.
Edward C. Jeffrey Professor of BiologyHarvard University Center for the EnvironmentDept. of Organismic and Evolutionary BiologyMicrobial Sciences Initiative
Find info concerning University Center MI CNA degree. Healthcare is one of the fastest-growing job areas, and for good reason. As the population ages, medical facilities will continue to expand rapidly.
Cocaine consumption affects around 13.4 mi people or 0.3% of the world population between 15 and 64 years old. The drug dependence has been described by many authors as a dysfunction of the brain reward system. Considering the effects of the cholinergic system on the drug reward and self-administration mechanisms, acetylcholine (Ach) may play an important role on cocaine dependence process. Then the present study aims to evaluate biperiden efficacy (a cholinergic antagonist) in attenuate compulsion, one o the main symptoms of the drug dependence. To accomplish this purpose 60 cocaine or crack male users between 18 and 50 years old will be study. This is a double-blind controlled and randomized placebo study. All the patients will be treated with brief intervention therapy (BIT), and half of them will receive biperiden (6mg/day) while the other half will receive placebo. The treatment efficacy will be evaluated through the comparison between the values obtained on the following measures before ...
Heather Congdon, PharmD, BCPS, CDE, associate professor in the Department of Pharmacy Practice and Science (PPS) at the University of Maryland School of Pharmacy and assistant dean for the School at the Universities at Shady Grove, has been named a co-director of the new Center for Interprofessional Education (IPE) at the University of Maryland, Baltimore (UMB). The Center, which officially launched on Nov. 20, is directed by Jane M. Kirschling, PhD, RN, FAAN, dean and professor of the School of Nursing, and monitors all of the IPE initiatives in which faculty, staff, and students at UMB are engaged.. "The University of Maryland School of Pharmacy has long been a proponent of interprofessional education and practice, a concept that improves patient outcomes and allows each health care professional to practice at the top of their license," says Natalie D. Eddington, PhD, FAAPS, FCP, dean and professor dean of the School of Pharmacy. "The naming of Dr. Congdon as a co-director of the Universitys ...
The Center for Biomedical Research promotes and supports biomedical research and education at Oakland University and allied institutions. It enhances collaborative efforts in biomedical research projects, recruits and retains outstanding biomedical researchers and supports their needs ...
Explore the underground laboratory of Dr. Peter Girguis and the Harvard University Department of Organismic and Evolutionary Biology during the HUBWeek Adventure, "Undersea Research and the Future of Science". In his labyrinth of underwater discoveries, meet the creatures that sparked animators imagination for Finding Nemo. Shed some light on modern oceanographic research and how the deep sea and its denizens play a critical role in supporting all life on Earth. Hear how renewable energy is finally becoming competitive with fossil-fuel sources. Finally, find out how discoveries in natural ecosystems are being used to treat and cure disease.. Though the deep sea represents the vast majority of our biosphere, we have literally seen less of our ocean floor than weve seen of the surface of Mars. Nonetheless, the deep sea is a critical part of our ecosystem, and the Girguis lab at Harvard University is committed to understanding how animals and microbes make a living in the deep sea. Their lab ...
Reviews the methods used to characterize environmental and occupational exposures. Presents approaches for biologically based exposure assessment matched to epidemiologic designs. Emphasizes evaluation of scientific literature. Course Activities: Students will critique 4 case study papers. Instructors will provide feedback ...
|p| Animal and Land Sciences research at Hartpury encompasses a range of research areas representing the interests and experience of our staff.|/p|
Click any of the links below to learn information about orientation at one of our off-campus centers. If you need information regarding orientation on our Ellensburg campus, click here.. ...
Description of Subjects: Fenway Health medical patients who have had at least 2 HIV primary care visits at Fenway in a 12 month period and are 18 years or older ...
Many diseases are associated with incredible pain and suf- fering. Others impair func- tion and independence to the extent that human dignity is eroded. In many instances the natural history of such conditions often leads ...
Statistics and Data Analysis Using R is a hands-on introduction to the R statistical software suite for biomedical scientists. It is assumed that the student is familiar with the plots and statistical summaries that are most commonly used in biomedical papers, but no formal background in statistics or programming is necessary. The primary objective is learning to use R, but the course also emphasizes the standards of practice that programmers and data analysts have implemented to ensure transparency, accuracy and accountability. Students are required to have a laptop ...
Kočí, Kamila; Matějů, Kateřina; Obalová, Lucie; Krejčíková, Simona; Lacný, Zdenek; Plachá, Daniela; Čapek, Libor; Hospodková, Alice; Šolcová, Olga (Applied Catalysis. B, Environmental. 2010, vol. 96, issues 3-4, p. 239-244.) ...
Consumer involvement and input is a crucial component of any UCEDD program. The UCEDD must involve consumers, in the form of a committee, who represent ...
Young adults with autism face many new expectations and challenges - with none of the support that is available during high school. BY DEBORAH RUDACILL...
On December of 2017, several members from the Association of University Centers on Disabilities (AUCD) network, along with other professionals from various backgrounds, convened to form the Inclusive Health Project Workgroup. The purpose of this workgroup was to assist in creating inclusion principles and guidelines for implementing health-related activities for people with intellectual disabilities (ID). These principles and guidelines would serve to support national-level organizations to adopt and promote inclusive approaches to health for people with ID, and provide useful information for organizations on how to foster inclusion of people with ID in national organizations. This exceptional workgroup, which encompassed of directors and specialists from University Centers for Excellence in Developmental Disabilities (UCEDD), used both their professional and individual experiences in the realm of disabilities/ID to develop the Foundational Principles for Sustainable Inclusion of People with
Assess patients gait and motor function to help determine antiparkinson effects, especially when starting drug therapy, or during dosing changes or addition of other antiparkinson drugs. Motor function should be assessed at different times of the day, such as when drugs are reaching peak therapeutic levels (i.e., 30-60 min after oral dose), as well as when drug effects are minimal (just before the next dose). ...
I tend to make a distinction between insults and insulting characterizations where the latter is relevant to the context of the current situation.. I would put that somewhere along the continuum between "painful truths" and "invidious comparisons" depending on the situation. As you say, if were arguing about hairstyles, then my massive combover is relevant.. The best we can do with irrelevancies are things on the order of "piece of shit". Since I started thinking about this stuff, Ive been trying to cut back on the irrelevancies because they are so common and weak that the reader seems to automatically edit them out. I used to call people "asshole" a lot but then I realized that it doesnt bother them at all, and just defocuses my attack. In my opinion the best and most effective insulting characterizations have to do with beliefs, manner of thought, actions and communications that are harmful to the person and/or others and can be obviously connected to the immediate situation. This is where ...
A final discussion dilemma appraisers confront is the irrelevancy trap. All of a sudden, in the middle of a discussion, you realize that the subject youre talking about has nothing to do with the core issue of the appraisees unacceptable performance.. Labeling an irrelevancy as such is unproductive. It only generates arguments. Dont waste your breath.. When you discover that youre in the middle of an active discussion of an irrelevant topic, the technique to use is "dismiss and redirect." Wait until your counterpart pauses for breath and then say, "As far as the way they used to handle this situation in your old company is concerned, Id like to talk about that separately. First, I need for you to agree that you will let me know any time a project deadline is slipping.". The keywords are separately and first. The magic dismiss-and-redirect technique can be used anytime a conversational counterpart raises an issue that you want to make go away. You dont say that its irrelevant, unimportant ...
I did not want to put words into your mouth, that is why I really wanted a definition for the entitlement classes. I do have to say though that your definition… well, it lacks definition.. I still hesitate to name any classes that you might consider entitlement classes because it would be dangerous for me to do that.. Are you basing your statements and opinions on experience or on interpreting writings of others. I have to ask because you are very liberal with your interpretation of writings… chosing not to read what the person is saying… instead you, "I return to the circumstances around the statement. YOu can read what you want into the actual words (his actual words). I am pragmatic about these things. What matters is the action that results. (as you interpret them to mean)" This shows a shocking denial of his intent and your twisting his words to create the results you wish his words to mean. He was very clear. Very specific concerning the type of behavior that concerned him… "The ...
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Right Steve, this guy from Nokia is obviously an example of the Peter Principle, people will tend to be promoted until they reach their position of incompetence .
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Basic substituted benzilic esters with distinctive anticholinergic effects are potential drugs for the treatment of urinary incontinence, duodenal and gastric ulcers and Parkinson disease. Derivatives of benzilic esters, exhibiting a combination of anticholinergic and dopaminergic effects, are of special interest because, as a consequence of their dualistic effect, they are in a position to form a new class of Antiparkinson drugs. As muscarinic receptor subtypes possess a large variety of functional properties, drugs which show less selectivity on muscarinic receptors exhibit atropine-like side effects. A reduction of these side effects may be achieved by the development of more selective anticholinergic compounds. The objective was to optimise the effect of N-Methyl-4-piperidyl benzilates through a variation of sterical parameters and the introduction of electronically differentiated substituents within the aromatic rings. The effect of sterical and structural variations was investigated in ...
Loughborough University and two healthcare partners have been awarded £70,000 for a major new study evaluating how emergency admissions to hospitals can be reduced.. The initiative will assess patient journeys through community based services as alternatives to admissions through Accident and Emergency (A&E) departments.. Supported by SimLean - a computer modelling and simulation program developed by the University - alongside interviews and focus groups, the study will investigate how the patient journey can be improved.. It will also look at how the principles of Lean - creating better value for service users whilst generating no waste in resources - can be applied to integrated health and care services.. The project builds on original work by Professor Zoe Radnor, co-director of the Universitys Centre for Service Management and Professor Stewart Robinson, Associate Dean for Research. Both are based in the Universitys School of Business and Economics.. Professor Radnor explains: ...
MARQUETTE, Mich.-The Northern Michigan University Volunteer Center will sponsor a "Be the Match" bone marrow registration drive. The drive will be held from 4:30-8:30 p.m. Monday, Sept. 23, in the Payne/Halverson lobby and from 9 a.m. to 2 p.m. Tuesday, Sept 24, in the University Center atrium. Registration is free and the procedure is painless and quick, requiring only a cheek swab to be entered into the national registry.. Participants could prove to be a match for someone suffering from one of 70 different diseases. Even if matched, choosing to donate bone marrow is entirely voluntary. For more information, contact the NMU Volunteer center at 906-227-2466 or [email protected] ...
MARQUETTE, Mich.-The Northern Michigan University Volunteer Center will sponsor a "Be the Match" bone marrow registration drive. The drive will be held from 4:30-8:30 p.m. Monday, Sept. 23, in the Payne/Halverson lobby and from 9 a.m. to 2 p.m. Tuesday, Sept 24, in the University Center atrium. Registration is free and the procedure is painless and quick, requiring only a cheek swab to be entered into the national registry.. Participants could prove to be a match for someone suffering from one of 70 different diseases. Even if matched, choosing to donate bone marrow is entirely voluntary. For more information, contact the NMU Volunteer center at 906-227-2466 or [email protected] ...
The Center for Microbial Interface Biology (CMIB) is a multidisciplinary research center focused on microbe-host interactions that was created by Dr. Larry Schlesinger in late 2002 which received official University Center status in 2006. It is housed in the Office of Health Sciences and is supported by the Medical Center and University. The title of the Center was created to embrace the broad biological studies applicable to the complex analysis of microbe-host interactions, i.e. the interface between microbes and their hosts.. There are currently 79 faculty members in the CMIB from throughout the OSU campus. The collective CMIB faculty is involved in and represents the fields of immunology, cell biology, pathology, biochemistry and pharmacology, microbiology, genetics, structural biology, and bioinformatics. Investigation by these researchers includes but is not limited to in vitro and animal studies, genomics, proteomics, and population-based studies. Emphasis areas in the Center are in ...
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Laboratory: Each preceptor has her/his own laboratory. Desk space and a personal computer will be available for each trainee. The laboratory of the Adult Division of Allergy-Immunology has 5,675 sq. ft. of space. The common area has 2 large cold rooms, autoclave room and a central dishwashing facility.. Clinical: Northwestern has 4 hospitals in close proximity: The Northwestern Memorial Hospital (NMH), The Prentice Womens Hospital (PWH), The Rehabilitation Institute of Chicago (RIC - ranked #1 nationally), and the Robert H. Lurie Childrens Hospital (LCH). The Allergy-Immunology Division has its own clinical research area located in our patient clinic in the Galter Pavilion.. Animal: All animal work is performed in the Northwestern University Animal Resources Facility under the direction of the Northwestern University Center for Comparative Medicine (CCM). The CCM is an AAALAC accredited facility and a member of AALAS.. Office: Each faculty and each trainee has their own desk and computer ...
Scientists at Israels Technion Institute of Technology have created a tiny robot able to crawl through a persons veins in order to diagnose and potentially treat artery blockage and cancer. The worlds smallest robot, with a diameter of one millimetre, it is powered by an external magnetic field allowing it to be controlled for an unlimited amount of time during medical procedures.. Oded Salomon, a research engineer in the Technion Faculty of Mechanical Engineerings Kahn Medical Robotics Laboratory, conceived the tiny robot together with Prof. Moshe Shoham and Dr Nir Schwalb, Technion alum of the lab and now a lecturer at the Ariel University Center. Their miniature "submarine" can negotiate the inner walls of blood vessels using tiny arms which will allow it to withstand blood pressure. The robot is powered by an external magnetic field allowing it to be controlled for an unlimited amount of time during medical procedures.. Known as the ViRob, it is an autonomous crawling micro-robot with ...
All University Orientation events are designed to create an environment that is positive, respectful, inclusive, and discrimination-free. While we encourage you to attend as many events as possible, events are not mandatory, and you are encouraged to take care of yourself and your needs. Please know that Queens University does not tolerate hazing, and all orientation events are alcohol-free.. Throughout University Orientation, help is always on hand! If you have any questions during the three days, call or visit the Nerve Centre, our main information hub, in the lower ceilidh of the John Deutsch University Centre (JDUC) and at 613-533-6254. Stay safe by using our bus shuttle and/or Walkhome when travelling at night, and download the SeQure app to hae safety information at your fingertips.. If you have any accessibility needs, please contact [email protected] to arrange for accommodations.. We are so excited to welcome you to Queens University as the Class of 2021!. ...
MEDFORD/SOMERVILLE, Mass. -- New technology at Tufts Universitys Center for Scientific Visualization is enabling researchers to translate the most abstract, complex scientific concepts into clearer, more precise 3-dimensional images than conventional visualization systems can create.
Global Nano Therapy market has been segmented on the basis of technology which includes Nanomaterial and biological device, Nano electronic biosensor, Molecular nanotechnology. On the basis of disease medication which consists of Brain tumor, Heart attack stroke, Posterior eye disease. Complete Report Available at https://www.marketresearchfuture.com/reports/nano-therapy-market .. Key Players for Wound Care Market:. Some of the key players for the Global Nano Therapy are:. Washington University center for multiple myeloma Nano therapy. Cancer therapy and research center at the University of Texas. Center for multiple myeloma Nano therapy (CMMN). Americas. · North America. · US. · Canada. · Latin America. Europe. · Western Europe. · Germany. · France. · Italy. · Spain. · U.K. · Rest of Western Europe. · Eastern Europe. Asia- Pacific. · Asia. · China. · India. · Japan. · South Korea. · Rest of Asia. · Pacific. The Middle East& Africa. The report for Global Nano Therapy Markets ...
Director, Database & Software Development The Johns Hopkins University Institute for Computational Medicine email: sgranite-at-jhu.edu {nid 1WO7} Stephen Granite is the Director of Database and Software Development at The Johns Hopkins University Center for Cardiovascular Bioinformatics and Modeling. He received a BS in Biology, with a dual major in Finance, from Harvey Mudd College. He has an MS in Computer Science with a focus in Bioinformatics and an MBA in Competitive Intelligence, both from The Johns Hopkins University. He is the Project Manager of the Cardiovascular Research Grid (CVRG; http://www.cvrgrid.org/) Project and primarily focuses on the infrastructure and deployment of the electrophysiological aspects of the CVRG. Prior to his current position, Stephen served as a Staff Bioinformatician at the National Institutes of Health Intramural Sequencing Center, providing and developing Bioinformatics tools utilized in the Comparative Vertebrate Sequencing Initiative and the Mammalian ...
The findings could help to identify brain abnormalities in ill patients, with the potential for electric or magnetic stimulation to modify abnormal rhythms, according to a study recently published in the Plos One journal.. Dr Anne Keitel, a postdoctoral researcher at Glasgow Universitys Centre for Cognitive Imaging, said: "When you look at all 115 areas of the brain you can find totally different rhythms. It seems a bit messy at first so we wanted to see if we could classify what was going on so we could see what to expect.". A group of 22 healthy adults were asked to simply sit still for a few minutes with their eyes open while their neural activity was monitored.. By measuring the magnetic fields produced by brain activity, the team were able to establish which part of the brain it came from and to analyse the individual rhythms.. Some parts of the brain had just two relatively slow oscillations, indicating that this part was focused on a single specific task. ...
Rejection of any kind is always hard to deal with, but when ones body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.. ...
In National Conference of Integration of Medical Sciences and Life Sciences for Innovative Medical Research dated 11-12 April, 2016 at University Centre of Excellence in Research,, Baba Farid University of Health Sciences, Faridkot. ...
A dyslexia research team at Yale Universitys Center for Learning and Attention lead by Dr. Sally Shaywitz has found a window on the brain through a new imaging technique.
The eminent economist and former Secretary of the Department of Finance, Dr T.K. Whitaker, was warmly received at NUI Galway today as the University announced the establishment of the Whitaker Institute for Innovation and Societal Change. Dr Whitaker played an instrumental role in devising the economic plan, which set Ireland on the road to regeneration in the early 1960s. Drawing inspiration from his unparalleled service to Ireland, the newly formed Whitaker Institute serves as the countrys largest research body focused on contemporary and relevant business, social and policy issues. Over 200 members make up the faculty with expertise spanning across the College of Business, Public Policy and Law and the College of Arts, Social Sciences and Celtic Studies. Subsuming the Universitys Centre for Innovation and Structural Change (CISC), the Whitaker Institute builds on a decade of research-excellence and policy-focused contributions supported by over €11 million in competitive national and ...
NEW YORK -- Jason Bordoffs swan song as a senior energy aide to President Obama came right before last years election, when he found himself stuck on the Upper West Side of Manhattan during the worst of Superstorm Sandy. Bordoffs week scrambling to address a quickly moving energy supply mess became an unexpected and pivotal moment in his career, before he left the administration last month to become director of Columbia Universitys Center on Global Energy Policy. ...
Resource: The Maryland Assistive Technology Network (MATN) is an online professional learning network that connects educators, families, and educational leaders who are engaged in improving learning and teaching through assistive and universally accessible technology. MATN is a service of the Johns Hopkins University Center for Technology in Education (JHU CTE). MATN membership is free and open to all people. MATN members have access to: ongoing discussions with experts from around the state, country, and globe; opportunities to participate in conversations with leaders to shape policy and practice in Maryland and beyond; free access to the bi-annual MATN Institutes held at varying Johns Hopkins University campuses; priority registration for the MATN complimentary webinar series; and, exclusive access to web-content and live professional learning opportunities designed to complement an exemplary "tool box" for a parent or educator. Visit the MATN resource page here… ...
Faculty eager to learn easier ways to present scholarly information have an opportunity today to learn from one of their own, Department of English lecturer Kristine Kelly.. Kelly, who teaches a class on experimental narratives and new media, will introduce an free web publishing platform called Scalar at noon today (June 23) in the Allen Memorial Librarys Herrick Room. The session is part of the programming of the University Center for Innovation in Teaching and Education (UCITE).. Developed at the University of Southern California, Scalar allows users to create digital projects that include their own writing as well as other content-images, videos and audio clips-to enhance understanding and engage viewers. Even better, Scalars developers specifically designed the platform to enable even those with minimal digital expertise to build dynamic and engaging projects.. Participants are encouraged to bring a laptop and set up an account on Scalar before the session.. Pizza and sodas will be ...
Researchers at the University of Edinburgh have found that the protein invadolysin, which is essential for healthy cell division, is present in lipid droplets - the parts of cells used to store fat.. The study also found that lower levels of invadolysin were linked to reduced amounts of fat deposits.. The findings, published in the Journal of Cell Science, could ultimately help scientists to better understand obesity-related complications, which can include diabetes, blood clotting and heart disease.. Professor Margarete Heck, at the Universitys Centre for Cardiovascular Science, said: "The presence of this protein in lipid droplets may suggest that it has a role in obesity. What we would like to understand is whether its presence is related to obesity, and if so, whether the proteins activity aggravates obesity and its consequences. Understanding its role will help us to better understand how the body stores fat.". Invadolysin was first identified by Professor Hecks laboratory in fruit ...
University Center Elected Members Present:. Ahmadi, Bell, Bibler, Callaway, Cochran, Dardenne, Darken, Hiestand, Ingle, Klieman, LeWinter, Marlowe, Mawata, McDonald, Meyer, Miles, Ozbek, Pringle, R. Smith, Sturzer, Tanner, J. Thompson, J. Trimpey, M. Trimpey, J. Vallier, B. Walton, Watson. Elected Members Absesnt:. Campa, Craig, Sanders, Venters, Weisbaker, Wiley. Ex-Officio Members Present:. Ernst, Jackson, Obear, Renneisen. Among the Guests Present:. Stinnett. Call to Order The second meeting of the UTC Faculty Council was called to order by Vice President Bibler, President Campa being out of town, at 3:15 PM.. Approval of Minutes. The minutes were not available because of the date of meeting but were promised for the first October meeting.. Committee on Committees. Bibler reported for the Committee on Committees. Margaret Smith of Human Services is to replace Jane Cahill on the Ad-Hoc Part-time Faculty Committee. Ms. Cahill is not with the University presently. Tom Waddell and Jack Freeman ...
CTRE is an Iowa State University center, administered by the Institute for Transportation.. Address: 2711 S. Loop Drive, Suite 4700, Ames, IA 50010-8664. Phone: 515-294- ...
CTRE is an Iowa State University center, administered by the Institute for Transportation.. Address: 2711 S. Loop Drive, Suite 4700, Ames, IA 50010-8664. Phone: 515-294- ...
Email: [email protected] View Privacy Policy An Equal Opportunity Employer The GCDD is funded under the provisions of P.L. 106-402. The federal law also provides funding to the Minnesota Disability Law Center,the state Protection and Advocacy System, and to the Institute on Community Integration, the state University Center for Excellence. The Minnesota network of programs works to increase the IPSII of people with developmental disabilities and families into community life.. ...
Scientists from Columbia Universitys Center for Radiological Research have shown that a narrow wavelength of ultraviolet light safely killed drug-resistant MRSA bacteria in mice, suggesting its potential to reduce surgical site infections.
September 26th- 28th 2012 - Gold Coast, Australia Hosted by Griffith University Centre for Cultural Research Creative communities is a well-worn phrase conventionally equated with notions of well-being, civic participation ...
An argument over the impact of electric heating broke out at the annual conference of the Institute of Domestic Heating and Environmental Engineers (IDHEE).Speaker Dr Brenda Boardman, from the Environmental Change Institute at Oxford University Centre for the Environment, said she was alarmed at the number of new flat developments in London with electric heating installed.She said electricity was still the energy source associated with the highest level of carbon ...
Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Direct Submission", Submitted (26-JUN-2003) Biotechnology, Royal Institute of Technology, Alba Nova University Centre, Roslagstullsbacken 21, S-106 91 Stockholm, Sweden ...
World Wide Web Style Manual. Yale University Center for Advanced Instructional Media (C/AIM). Authors, Patrick J. Lynch and Sarah Horton
Eventbrite - CISCRP presents AWARE for All - D.C. 2018 - Thursday, April 19, 2018 at Armour J. Blackburn University Center, Washington, DC. Find event and registration information.
Ive just started as an "Honorary Fellow" through Victoria Universitys Centre for Cultural Diversity and Wellbeing on a new project to run through 2016, possibly longer, titled (for the moment) "Ideating […]. ...
The discovery of unexpected magnetic interactions between ultrasmall specks of rust is leading scientists at Rice Universitys Center for Biological
We have used JMP extensively, and find it very useful. the academic price is quite reasonable. Unfortunately, I had to let my JMP expert go, due to a lack of funding... Marty On 8/2/06, Xiaowei JIANG ,xiaowei.jiang at msn.com, wrote: , , Dear all, , , Does anyone has the experience using JMP Genomics toolkit, if so, what do , you think of this environment specificly according to your experience? , , I am currently writing a case study report for this new platform. , , Thank you in advance. , , For more information please refer to , http://www.jmp.com/software/genomics/index.shtml , , , , Best regards, , Xiaowei JIANG , ---------------------------------------- , University Center for Statistics , Faculty of Science , Katholieke Universiteit Leuven,Belgium , ucs.kuleuven.be , ---------------------------------------- , MSc Statistics/Mathematics 2005-2006 , MSc Bioinformatics, BEng Computer Science , ---------------------------------------- , ...
Jan. 10, 2011)--UTSA Hillel, a Jewish organization for students, faculty and staff, will host a free screening of two Mel Brooks movie comedies beginning at 6:30 p.m., Thursday, Jan. 13 in the University Center Ash Room (2.03.06) on the Main Campus. The event is free and open to the UTSA community.. It will be an evening of films, food and friends in the groups first meeting of the spring semester. There also will be announcements about upcoming Hillel events.. The first screening will begin at 6:30 p.m. with "History of the World: Part I." At approximately 8 p.m., watch "Young Frankenstein.". >> Read more and RSVP at the Hillel Facebook page.. For more information, e-mail Joseph Markowitz.. ...
The article focuses on the use of online avatars to communicate information to employees regarding benefits. According to Steve Pappadakes of Visyt, avatars free up human resources (HR) people to do more work. It discusses the advantages of avatars to HR personnel. It also presents the results of the report on avatars from the Stanford University Center for the Study of Language and Information in Palo Alto, California which revealed that avatars can be leveraged to brand corporate messages ...
...Is it possible to put a price tag on the natural world? A researcher a...Academic Dr Marion Potschin of the Universitys Centre for Environmen...In a paper published in the journal BioScience Dr Potschin and...The idea that nature provides a range of benefits to society in the fo...,Valuing,nature,is,not,enough,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
World Wide Web Style Manual. Yale University Center for Advanced Instructional Media (C/AIM). Authors, Patrick J. Lynch and Sarah Horton
If you fit into the Intermediate-Risk category you have many treatment choices, and in order to make the best decision you need to get opinions from multiple specialists with state-of-the-art knowledge, and equipment. You will have already seen an urologist who, if you are a candidate for surgery, is likely to have recommended a radical prostatectomy. If this is the case, dont be shy. You owe it to yourself to ask the tough questions: What are the risks? How many procedures has he performed overall, and how many within the past twelve months? Does he perform nerve-sparing surgery, and if so what is his success rate with preservation of potency and continence? You will usually find the most experienced surgeons at university centers. But an urologist who is well trained and does 100 procedures a year-and who you feel comfortable with-is also a good bet ...
Staff development session presented to Open University Centre for Law, Milton Keynes. Co-presenter Karen Barton discussed e-portfolios.
Comments are moderated. We review them in an effort to remove foul language, commercial messages, abuse, and irrelevancies.. ...
The Sunday horror serial, once a spellbinding mix of chills, mystery and sex, is now a zombie of itself.. In Alan Balls final season as show runner, "True" seems to have about 30 characters and just as many stories.. HBO did not release screeners for the upcoming episodes, but if the cable networks press teasers are any indication, the season will continue its shuffle toward the great TV graveyard of irrelevancy. (The premium channel has already renewed the show for a sixth season.). In tonights episode (at 9), "Everybody Wants to Rule the World," Eric (Alexander Skarsgard) tries to escape, again, the Authority - but dont count on him getting far. Gran (Lois Smith) makes another crossover from the great beyond to give Sookie (Anna Paquin) a clue about her parents deaths. Since just about everyone has been wandering down the dead end of memory lane this season, Alcide (Joe Manganiello) recalls his pack initiation.. Next week, in "Gone, Gone, Gone," the vamps jihad against humans escalates, ...
In the five months since their third successive electoral humiliation the Tories, wallowing in self-loathing, have edged perilously close to political irrelevance. But what a difference a day makes! Ken Clarke and David Cameron at last gave this battered old party a reason to believe in itself
The second idea, of which I am less enthusiastic, is to tie the ethnotypes to phenotypes, stressing functional genes (and, as above, possibly dividing the ethnotypes, if desired, into more specific traits). Now, this confuses my use of the ethnotype concept - that is genetic - with the more anthropological phenotypic view. Im not defining ethnotype to describe a racial phenotype or set of phenotypes. Im using it to express the reality that while individual phenotypes are ephemeral, the range of possible genotypes of an ethny can be reasonably stable over long periods of evolutionary time. And by genotype, I consider the entire genetic integration of individuals of a population, not individual alleles in isolation. Further, while I am willing to grant (true) functional genes a higher per-allele value than (true) non-functional genes (since the functional ones influence their own replication, I do not - for reasons I have discussed many times - relegate non-functional genes to irrelevance. It is ...
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Dont go there," I warn, because Ill be pulled in the directions of then and now, and I wont know where I should be.. "But dont forget," I remind, because this time is on the cusp of irrelevance. You see, its not enough that he is her namesake. Its not enough that we labeled all the black and white photographs. My son must know who she was, who they were, what they felt, did and said. These were his people. If he doesnt know who they are, he wont know a part of himself.. So, I am stretching my arms across the century holding on to what is ours. To what was my grandmothers childhood spanning two continents; to the villa in Nuremberg, to the New York City apartment; connecting the points of hers and his, hoping to transmit the inexplicableness of what was. How hard it is when so much is missing.. Why didnt I ask her how she dealt with sadness? How she found joy during joyless times. Her greatest pain, her deepest regret? And why didnt I ask her about motherhood? The truth is, I never ...
With the Nets sitting last in the Eastern Conference, spiraling on a seven-game skid and fast approaching irrelevance, they acknowledge they need more...
Since its founding in 2001, the Nebraska University Center for Information Assurance (NUCIA) has helped improve the posture of information assurance awareness locally, regionally and nationally. The collaborative efforts of faculty, students and community partners have earned UNO the distinction of being named a Center of Academic Excellence in Information Assurance Education by the National Security Agency (NSA).. Studying information assurance and cybersecurity is a little bit like studying medicine: theres an endless list of applications and possibilities. Other IS&T disciplines such as computer science and bioinformatics intertwine with cybersecurity coursework. Theres even an overlap with criminal justice.. Any company that conducts electronic commerce will need cybersecurity. Security threats are continually evolving, and they range from hacking a home-based personal computer to large-scale communication systems. NUCIA prepares students to become security professionals capable of ...
PNA Innovations co-founders Bruce A. Armitage, Ph.D., and Danith H. Ly, Ph.D., are featured on the InnovationCast (I-Cast) produced by Carnegie Mellon Universitys Center for Technology Transfer and Enterprise Creation (CTTEC).. Armitage and Ly describe PNA Innovations gamma peptide nucleic acid (gPNA) technology, a molecular hybrid of peptides and nucleic acids with that binds with exceptionally high affinity to complementary DNA and RNA targets.. "What is unique about gPNA, the platform this company is built on, is that as opposed to regular PNA that is commercially available and has been around for the last 20 years, its already pre-organized into a right-hand helix to mimic that of the bound DNA and RNA target," Ly said. "So in addition to binding single-stranded DNA and RNA, it can also invade double- stranded DNA, and I think that is the unique feature of this particular platform ...
Two small studies reported suboptimal therapy adherence in Parkinsons disease. We conducted a larger multicenter European study to assess medicine-taking behavior. Parkinsons disease patients taking dopaminergic therapy were enrolled in 8 centers in 5 countries, and disease severity and demographics recorded. Antiparkinson drug adherence was measured for 4 weeks using electronic monitoring bottles which record the date and time of cap opening (Aardex®, Switzerland). One hundred twelve patients, mean age 65 years (standard deviation (SD) 10), with Parkinsons disease for 7.7 (SD 8.2) years completed the study. Total median adherence (doses taken/doses prescribed) was 97.7% (interquartile range [IQ] 90.6-100), days adherence (correct dose days) was 86.2% (IQ 61.1-96.2) and timing adherence (doses taken at correct time intervals) was 24.4% (IQ 5.3-56.5). Fourteen patients (12.5%) took less than 80% of prescribed doses, which was defined as suboptimal adherence. Patients with satisfactory ...
The Ohio State University created the Center for Clinical and Translational Science (CCTS) to catalyze research teams and facilitate innovation through creation...
ABDEEN, Z., BERMAN, T., AZMI, K., ABU SEIR, R., AGHA, H., EIN-MOR, E., GOEEN, T., STEIN, Y., RICHTER, E. & CALDERON-MARGALIT, R. 2016. Urinary organophosphate metabolite levels in Palestinian pregnant women: results of the Middle East Regional Cooperation Project. International Journal of Environmental Health Research, 26, 254-266. BERMAN, T., GOLDSMITH, R., LEVINE, H. & GROTTO, I. 2016. Human biomonitoring in Israel: Recent results and lessons learned. International Journal of Hygiene Environ Health, 16, 30107-9. BERMAN, T., LEVINE, H., GAMZU, R. & GROTTO, I. 2012. Trends in reproductive health in Israel: implications for environmental health policy. Israel Journal of Health Policy Research, 1. CHIU, Y.-H., GASKINS, A. J., WILLIAMS, P. L., MENDIOLA, J., JORGENSEN, N., LEVINE, H., HAUSER, R., SWAN, S. H. & CHAVARRO, J. E. 2016. Intake of fruits and vegetables with low-to-moderate pesticide residues is positively associated with semen-quality parameters among young healthy men. Journal of ...
Macek, B., et al. Global and Site-Specific Quantitative Phosphoproteomics: Principles and Applications, Annu. Rev. Pharmacol. Toxicol. 2009. 49: 199-221. doi: 10.1146/annurev.pharmtox.011008.145606 ...
Reed, D. , J. Herod, and J. Sickel. A comparison of larval development in the zebra mussel (Dreissena polymorpha) up to the free-swimming trochophore stage in Tennessee and Ohio River water. Proceedings of the Seventh Symposium on The Natural History of Lower Tennessee and Cumberland River Valleys. Sponsored by the Austin Peay State University Center for Field Biology and the Murray State University Center for Reservoir Research. 1997 ...
Reed, D. P., J. J. Herod, and J. B. Sickel. 1997. A comparison of larval development in the zebra mussel, Dreissena polymorpha, (Bivalvia: Dreissenidae) up to the free-swimming trochophore stage in Tennessee and Ohio River water. Proceedings of the seventh symposium on the natural history of lower Tennessee and Cumberland River valleys, Austin Peay State University Center for Field Biology and Murray State University Center for Reservoir Research. 7:85-98. ...
Presented by Jeffrey Hazey, MD at the SAGES 2014 Meeting; Panel - Endoscopic Management of Bariatric Complications operative strategies-2:34 initial clinical presentation-2:51 IOC-3:48 percutaneous or endoscopic strategies-4:55 antegrade/percutaneous approach after placement of PTC-6:14 background with c Keyword(s): 12 Fr sheath, 15 mm trocar, 30 Fr access, 30 Fr G-tube, 6 wk interval ERCP, access to […] ...
The field of genetics is expanding at an ever increasing pace with hardly a week going by without news of the discovery of a specific gene for a disease, the development of a new technique to manipulate genes or a gene target for therapy.. There are many ethical considerations being thrown up by these fascinating developments, and for those who enter this field there will be some difficult decisions to make. The list seems endless, but one thing is for sure these are extremely stimulating times in which to be a geneticist.. In this latest blog from Dr Elizabeth OBrien (pictured), Programme Leader for Medical Genetics, find out what you should be considering before embarking on the course, as well as the kind of questions you should be asking yourself. Do you have a real interest and enthusiasm for the subject? There are many concepts that you will need to understand as you progress, and this interest will help you to gain the necessary knowledge to truly understand the subject and to follow ...
Abstract: A pandemic influenza occurs when a new strain of influenza virus surfaces in the human population and spreads efficiently from person to person. The use of pharmaceutical interventions (prescription antiviral drugs and vaccine) plays an important role in a multi-faceted public health response to an infectious disease outbreak. We explore consequences of decisions on the amount of antiviral drug regimens to stockpile and the strategies for prophylaxis use of antivirals during an influenza pandemic. We also evaluate health benefits of different prophylactic antiviral use strategies in terms of disease attack rate and hospital surge arrivals considering uncertainties surrounding influenza spread and containment ...
There is no AED or medication that has been demonstrated to affect the development of post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic receptor, that is widely used as an anti Parkinson drug. The investigators data with animal models of epilepsy indicate that anti-muscarinic agents might affect the natural course of the disease in the case of post-traumatic epilepsy ...
This is the accessible text file for GAO report number GAO-11-750 entitled Financial Derivatives: Disparate Tax Treatment and Information Gaps Create Uncertainty and Potential Abuse which was released on October 20, 2011. This text file was formatted by the U.S. Government Accountability Office (GAO) to be accessible to users with visual impairments, as part of a longer term project to improve GAO products accessibility. Every attempt has been made to maintain the structural and data integrity of the original printed product. Accessibility features, such as text descriptions of tables, consecutively numbered footnotes placed at the end of the file, and the text of agency comment letters, are provided but may not exactly duplicate the presentation or format of the printed version. The portable document format (PDF) file is an exact electronic replica of the printed version. We welcome your feedback. Please E-mail your comments regarding the contents or accessibility features of this document ...
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Article: "A True Picture of Black Skin" by Teju Cole. You may have read about the recent relaunch of the New York Times Magazine, which includes some fairly dramatic changes in design, content, and, in particular, their online presence. There are quite a few things about this that sound exciting to me, including the fact that they will be printing poetry every week and are turning "The Ethicist" into a podcast. Probably the most exciting thing, though, is a section called "The Ons," which will feature four different critics in rotation, each focusing on a different area or field; one of these will be Teju Cole, writing about photography. Ive really enjoyed both of Teju Coles novels, particularly Open City, as well as some of his other writing on photography; he is an incredibly intelligent and thoughtful writer, and if the level of discussion in the magazine in general is anywhere close to his standard, it will be fantastic. This first piece is about the photographer Roy DeCarava, of whom Id ...
IRVINE - UC Irvine researchers have developed a technique that enables them to see a pathway in the human brain to the area that stores memories, one of the project scientists said today.. Craig Stark, the principal investigator and interim director of the universitys Center for the Neurobiology of Learning and Memory, said researchers used new techniques that offer higher-resolution images from an MRI machine, enabling them to find the long-hidden section in the brain.. The discovery of the so-called Perforant Path could help speed up diagnoses of Alzheimers disease, Stark said.. "Weve long known this is one of the main connections between two portions of the brain responsible for episodic memory, Stark said. "The problem has been that while we can look at it in a rat after dissecting the brain, or in non-human primates, but to actually see it in humans, and, more importantly, in perfectly healthy humans in a non-invasive way is something weve never been able to do until now.. The ...
Eventbrite - The Post Graduate Center presents The Heart of the Matter: Concepts and Techniques in the Treatment of Survivors of Childhood Sexual Abuse (CSA Certificate Workshop #3) - Friday, October 7, 2016 at University Center, Chester, PA. Find event and registration information.
In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit ...
The technology was developed by Philip Low, the Ralph C. Corley Distinguished Professor of Chemistry at Purdue University, director of the Purdue University Center for Drug Discovery and co-founder of On Target Laboratories. "The optical imaging technology is another important milestone in cancer treatment advancements being piloted by Phil Low and other promising researchers at Purdue," said Mitch Daniels, Purdue University president. "It also is a prime example of how innovations being developed in Indiana can be advanced through partnerships with other world-class institutions like the Leiden University Medical Center in the Netherlands." On Target Laboratories lead molecule OTL38 achieved first-in-humans status at the Center for Human Drug Research, affiliated with Leiden University. It was the first time the compound was given to humans as part of testing. This clinical trial in healthy volunteers is complete and it demonstrated the safety of the molecule at various doses. The next step in ...
In this nursing home study, polypharmacy per se was not found to be a risk factor for fall-related injuries: injuries were associated with the use of multiple drugs (7 or more), but only when an injurious fall risk-increasing drug (antiarrhythmic or antiparkinson drug) was part of the patients therapeutic regimen. Multiple medications, or particular medication classes, were not clearly associated with injurious falls. Several literature reports support the hypothesis that these active principles can contribute to predisposing patients to falls. In particular, a meta-analysis study showed digoxin, type 1a antiarrhythmic and diuretic use to be associated with falls in older adults [5], while in another study, hip-fracture patients, compared with matched controls, were more frequently prescribed antiparkinson drugs [22]. Polypharmacy per se, arbitrarily defined as the use of four or more medications, was recently shown not to be an independent risk factor for falls in a population-based setting ...
Sarcocystosis is caused by species of Sarcocystis, an intracellular protozoan parasite in the phylum Apicomplexa. These parasites have an indirect life cycle, cycling between a definitive and an intermediate host. Intestinal infections occur in the definitive host, and tissue invasion is seen in the intermediate host. More than a hundred species of Sarcocystis are parasites of domestic and wild animals. Many of these infections are asymptomatic, particularly in the definitive host. Equine protozoal myeloencephalitis is usually caused by Sarcocystis neurona. Neospora caninum and/or Neospora hughesi, not discussed in this outline, have also been implicated in some cases. Symptomatic infections caused by Sarcocystis species are reported occasionally in other domestic animals. Humans are a definitive host for S. suihominis, found in pork, and S. hominis, found in beef. These parasites infect the intestines. Humans can be intermediate hosts for a variety of other Sarcocystis species. The parasites are found
Avian chlamydiosis is a zoonotic disease of birds caused by the intracellular bacterium Chlamydophila psittaci. This disease is called psittacosis in humans. It may be called either avian chlamydiosis or psittacosis in psittacine birds; the term avian chlamydiosis is generally used in other avian species. Infections are particularly common among psittacine birds and pigeons, but most or all species of birds are probably susceptible. Some birds carry this organism asymptomatically. Others become mildly to severely ill, either immediately or after they have been stressed. Significant economic losses may be seen in turkeys and ducks, and high mortality can occur in clinically affected psittacines. Humans are readily infected by C. psittaci. In 1929, exposure to imported pet psittacines caused a pandemic in the U.S. and Europe. Since that time, improved screening and control of avian infections have decreased the incidence of human disease. However, C. psittaci is difficult to eliminate entirely; sporadic
Researchers at the Icahn School of Medicine at Mount Sinai have identified an impairment in a brain region that might explain why it is difficult for persons with cocaine addiction to cease using the drug.. Using functional magnetic resonance imaging data, the research team found among cocaine-addicted individuals an impairment in the ventromedial prefrontal cortex, which governs impulse and self-control, possibly explaining why these individuals cannot form new associations for certain stimuli.. "Our study data suggests that it will be hard for longtime cocaine users to unlearn what once was a positive experience if this unlearning or new learning relies on this brain region to be effective," said Anna Konova, PhD, formerly with the Icahn School and now a postdoctoral fellow at New York Universitys Center for Neural Science.. The study compared 18 chronic cocaine users to 15 non-using controls on "extinction learning" activities resembling the exposure therapy often used to treat anxiety ...
Location: Cleveland Museum of Natural History. Tuesday, May 1 Nandini Trivedi, Department of Physics, The Ohio State University. Super Conductors and Super Fluids: The Quantum Dance of Matter: Pairing and Superconductivity. How do electrons and atoms get organized at very low temperatures and how do new phases of matter emerge? Even a very small attraction between electrons in a metal can cause pairs of them to bind together, achieving unusually low energy. These pairs are responsible for superconductivity -and a Nobel Prize in physics! In certain "exotic" cold materials, ultracold atoms can be trapped and organized using light. Rumor has it that Dr. Trivedi will attempt to perform actual experiments for us during the lecture!. Location: CWRU, Tinkham Veale University Center. Tuesday, May 8. Yohannes Haile-Selassie, Curator & Head of Physical Anthropology, Cleveland Museum of Natural History. Early Ape and Human Evolution: New Discoveries from the Cradle of Humankind. Famed paleoanthropologist ...
Amitriptyline/perphenazine (Duo-Vil, Etrafon, Triavil, Triptafen) is a formulation that contains the tricyclic antidepressant amitriptyline and the medium-potency typical (first-generation) antipsychotic, perphenazine. In the United States amitriptyline/perphenazine is marketed by Mylan Pharmaceuticals Inc. and Remedy Repack Inc. In the United States amitriptyline/perphenazine is indicated for the treatment of patients with: Moderate-severe anxiety and/or agitation and depression Depression and anxiety in association with chronic physical disease Schizophrenia with prominent depressive symptoms Common (>1% incidence) adverse effects include Sedation Hypertension - high blood pressure. Neurological impairments (such as extrapyramidal side effects which include dystonia, akathisia, parkinsonism, muscle rigidity, etc.) Anticholinergic side effects such as: - Blurred vision - Constipation - Dry mouth - Nasal congestion Increased appetite Weight gain Nausea Dizziness Headache Vomiting Unknown ...
Rockefeller Universitys Center for Clinical and Translational Science, established a decade ago to accelerate the pace of translating scientific discoveries into interventions shown to improve health, has received $27 million from the National Institutes of Health to fund ongoing and expanded work over the next five years. The Clinical and Translational Science Award (CTSA), which has funded the center since its inception, is designed to improve the translational research process and foster innovation in research methods, training, and career development.. The award maintains CTSA funding that began in 2006, when Rockefeller was selected as one of the first 12 institutions to receive it, and then continued through the universitys successful renewal in 2011. With this award, which is technically not a renewal, Rockefeller has received more than $115 million in CTSA funding.. "Im delighted that we will continue to be funded through the CTSA," says Center for Clinical and Translational Science ...
From the Section of Orthodontics, and the Department of Oral and Maxillofacial Surgery, and the Department of Pediatrics, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Pediatrics, Division of Rheumatology, Alberta Childrens Hospital, University of Calgary, Calgary, Alberta; Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada; the Specialist Oral Health Center for Western Norway, Rogaland, Stavanger, Norway; Department of Orthodontics, University of Rostock, Rostock, Germany; Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama; Oral and Maxillofacial Surgery and Pediatrics, Emory University, and Childrens Healthcare of Atlanta, Atlanta, Georgia, USA; Clinic for Orthodontics and Pediatric Dentistry, University Center for Dental Medicine, University of Basel, Basel, Switzerland; Field of Dentistry, School of Medicine, University of Tampere and Oral and Maxillofacial Unit, Tampere University ...

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