Warfare involving the use of living organisms or their products as disease etiologic agents against people, animals, or plants.
Procedures outlined for the care of casualties and the maintenance of services in disasters.
An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed)
Preventive emergency measures and programs designed to protect the individual or community in times of hostile attack.
An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.
Regulations to assure protection of property and equipment.
Living organisms or their toxic products that are used to cause disease or death of humans during WARFARE.
A species of bacteria that causes ANTHRAX in humans and animals.
A live VACCINIA VIRUS vaccine of calf lymph or chick embryo origin, used for immunization against smallpox. It is now recommended only for laboratory workers exposed to smallpox virus. Certain countries continue to vaccinate those in the military service. Complications that result from smallpox vaccination include vaccinia, secondary bacterial infections, and encephalomyelitis. (Dorland, 28th ed)
A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.
The etiologic agent of TULAREMIA in man and other warm-blooded animals.
Laws and regulations concerned with industrial processing and marketing of foods.
Collective behavior of an aggregate of individuals giving the appearance of unity of attitude, feeling, and motivation.
An agency of the UNITED STATES PUBLIC HEALTH SERVICE that conducts and supports programs for the prevention and control of disease and provides consultation and assistance to health departments and other countries.
A state of extreme acute, intense anxiety and unreasoning fear accompanied by disorganization of personality function.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
The systematic application of information and computer sciences to public health practice, research, and learning.
A species of ORTHOPOXVIRUS causing infections in humans. No infections have been reported since 1977 and the virus is now believed to be virtually extinct.
Management of public health organizations or agencies.
Agencies of the FEDERAL GOVERNMENT of the United States.
Health care professionals, technicians, and assistants staffing LABORATORIES in research or health care facilities.
Decisions for determining and guiding present and future objectives from among alternatives.
A viral disease infecting PRIMATES and RODENTS. Its clinical presentation in humans is similar to SMALLPOX including FEVER; HEADACHE; COUGH; and a painful RASH. It is caused by MONKEYPOX VIRUS and is usually transmitted to humans through BITES or via contact with an animal's BLOOD. Interhuman transmission is relatively low (significantly less than smallpox).
Accidentally acquired infection in laboratory workers.
Education and training in PUBLIC HEALTH for the practice of the profession.
The activities and endeavors of the public health services in a community on any level.
A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
The etiologic agent of PLAGUE in man, rats, ground squirrels, and other rodents.
The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.
Refusal of the health professional to initiate or continue treatment of a patient or group of patients. The refusal can be based on any reason. The concept is differentiated from PATIENT REFUSAL OF TREATMENT see TREATMENT REFUSAL which originates with the patient and not the health professional.
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
A family of RNA viruses, of the order MONONEGAVIRALES, containing filamentous virions. Although they resemble RHABDOVIRIDAE in possessing helical nucleocapsids, Filoviridae differ in the length and degree of branching in their virions. There are two genera: EBOLAVIRUS and MARBURGVIRUS.
Organized efforts to insure obedience to the laws of a community.
Monitoring of rate of occurrence of specific conditions to assess the stability or change in health levels of a population. It is also the study of disease rates in a specific cohort such as in a geographic area or population subgroup to estimate trends in a larger population. (From Last, Dictionary of Epidemiology, 2d ed)
Infectious diseases that are novel in their outbreak ranges (geographic and host) or transmission mode.
Vaccines or candidate vaccines used to prevent ANTHRAX.
Facilities equipped to carry out investigative procedures.
A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
Notification or reporting by a physician or other health care provider of the occurrence of specified contagious diseases such as tuberculosis and HIV infections to designated public health agencies. The United States system of reporting notifiable diseases evolved from the Quarantine Act of 1878, which authorized the US Public Health Service to collect morbidity data on cholera, smallpox, and yellow fever; each state in the US has its own list of notifiable diseases and depends largely on reporting by the individual health care provider. (From Segen, Dictionary of Modern Medicine, 1992)
A genus of the family POXVIRIDAE, subfamily CHORDOPOXVIRINAE, comprising many species infecting mammals. Viruses of this genus cause generalized infections and a rash in some hosts. The type species is VACCINIA VIRUS.
Programs of surveillance designed to prevent the transmission of disease by any means from person to person or from animal to man.
The use or threatened use of force or violence against persons or property in violation of criminal laws for purposes of intimidation, coercion, or ransom, in support of political or social objectives.
Administration of a vaccine to large populations in order to elicit IMMUNITY.
A species of ORTHOPOXVIRUS causing an epidemic disease among captive primates.
Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.
A highly fatal, acute hemorrhagic fever, clinically very similar to MARBURG VIRUS DISEASE, caused by EBOLAVIRUS, first occurring in the Sudan and adjacent northwestern (what was then) Zaire.
A genus in the family FILOVIRIDAE consisting of several distinct species of Ebolavirus, each containing separate strains. These viruses cause outbreaks of a contagious, hemorrhagic disease (HEMORRHAGIC FEVER, EBOLA) in humans, usually with high mortality.
A disease of humans and animals that resembles GLANDERS. It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia.
Procedures, strategies, and theories of planning.
A synthetic tetracycline derivative with similar antimicrobial activity.
A species of gram-negative, aerobic bacteria that is the etiologic agent of epidemic typhus fever acquired through contact with lice (TYPHUS, EPIDEMIC LOUSE-BORNE) as well as Brill's disease.
Integrated set of files, procedures, and equipment for the storage, manipulation, and retrieval of information.
The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.
Time period from 1901 through 2000 of the common era.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
The interactions between representatives of institutions, agencies, or organizations.
A species of gram-negative bacteria that grows preferentially in the vacuoles of the host cell. It is the etiological agent of Q FEVER.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).
Antisera from immunized animals that is purified and used as a passive immunizing agent against specific BACTERIAL TOXINS.
The exposure to potentially harmful chemical, physical, or biological agents by inhaling them.
Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.
Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.
The presence of bacteria, viruses, and fungi in the air. This term is not restricted to pathogenic organisms.
The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
Heat and stain resistant, metabolically inactive bodies formed within the vegetative cells of bacteria of the genera Bacillus and Clostridium.
Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.
A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
The concept pertaining to the health status of inhabitants of the world.
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
Programs of disease surveillance, generally within health care facilities, designed to investigate, prevent, and control the spread of infections and their causative microorganisms.
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.
Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
The use of biological agents in TERRORISM. This includes the malevolent use of BACTERIA; VIRUSES; or other BIOLOGICAL TOXINS against people, ANIMALS; or PLANTS.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Substances that reduce the growth or reproduction of BACTERIA.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
Substances elaborated by bacteria that have antigenic activity.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Proteins found in any species of bacterium.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Elements of limited time intervals, contributing to particular results or situations.

Implications of pandemic influenza for bioterrorism response. (1/535)

The 1918-1919 influenza pandemic (Spanish flu) had catastrophic effects upon urban populations in the United States. Large numbers of frightened, critically ill people overwhelmed health care providers. Mortuaries and cemeteries were severely strained by rapid accumulation of corpses of flu victims. Understanding of the outbreak's extent and effectiveness of containment measures was obscured by the swiftness of the disease and an inadequate health reporting system. Epidemic controls such as closing public gathering places elicited both community support and resistance, and fear of contagion incited social and ethnic tensions. Review of this infamous outbreak is intended to advance discussions among health professionals and policymakers about an effective medical and public health response to bioterrorism, an infectious disease crisis of increasing likelihood. Elements of an adequate response include building capacity to care for mass casualties, providing emergency burials that respect social mores, properly characterizing the outbreak, earning public confidence in epidemic containment measures, protecting against social discrimination, and fairly allocating health resources.  (+info)

Infection in the twenty-first century: predictions and postulates. (2/535)

The late Paul Garrod, in whose honour this lecture is named, was 'the right man at the right time'. He seized the opportunities offered by the dawning of the chemotherapeutic era with vigour and enthusiasm and was a formidable link between the traditional laboratory-based bacteriologist and the more clinically orientated 'modern' medical microbiologist. Professor Garrod was a founder member of the British Society for Antimicrobial Chemotherapy and I had the privilege of meeting him on many occasions. He would have relished the many challenges facing today's microbiologists, infectious disease physicians and public health experts. These will have major implications for antimicrobial chemotherapy in the twenty-first century. The emergence and prevalence of infectious diseases, and the necessity for discovering therapies to treat them, are influenced by many factors. In this lecture I will discuss four which could have a major influence on infectious diseases in the twenty-first century-global warming, biological warfare/terrorism, the dissemination of infections, including those caused by resistant pathogens, by travellers and certain untreatable zoonotic diseases.  (+info)

The role of the clinical laboratory in managing chemical or biological terrorism. (3/535)

BACKGROUND: Domestic and international acts of terrorism using chemicals and pathogens as weapons have recently attracted much attention because of several hoaxes and real incidents. Clinical laboratories, especially those affiliated with major trauma centers, should be prepared to respond rapidly by providing diagnostic tests for the detection and identification of specific agents, so that specific therapy and victim management can be initiated in a timely manner. As first-line responders, clinical laboratory personnel should become familiar with the various chemical or biological agents and be active participants in their local defense programs. APPROACH: We review the selected agents previously considered or used in chemical and biological warfare, outline their poisonous and pathogenic effects, describe techniques used in their identification, address some of the logistical and technical difficulties in maintaining such tests in clinical laboratories, and comment on some of the analytical issues, such as specimen handling and personal protective equipment. CONTENT: The chemical agents discussed include nerve, blistering, and pulmonary agents and cyanides. Biological agents, including anthrax and smallpox, are also discussed as examples for organisms with potential use in bioterrorism. Available therapies for each agent are outlined to assist clinical laboratory personnel in making intelligent decisions regarding implementation of diagnostic tests as a part of a comprehensive defense program. SUMMARY: As the civilian medical community prepares for biological and chemical terrorist attacks, improvement in the capabilities of clinical laboratories is essential in supporting counterterrorism programs designed to respond to such attacks. Accurate assessment of resources in clinical laboratories is important because it will provide local authorities with an alternative resource for immediate diagnostic analysis. It is, therefore, recommended that clinical laboratories identify their current resources and the extent of support they can provide, and inform the authorities of their state of readiness.  (+info)

Lessons from the West Nile viral encephalitis outbreak in New York City, 1999: implications for bioterrorism preparedness. (4/535)

The involvement and expertise of infectious disease physicians, microbiologists, and public health practitioners are essential to the early detection and management of epidemics--both those that are naturally occurring, such as the 1999 outbreak of West Nile virus (WN virus) in New York City, and those that might follow covert acts of bioterrorism. The experience with the WN virus outbreak offers practical lessons in outbreak detection, laboratory diagnosis, investigation, and response that might usefully influence planning for future infectious disease outbreaks. Many of the strategies used to detect and respond to the WN virus outbreak resemble those that would be required to confront other serious infectious disease threats, such as pandemic influenza or bioterrorism. We provide an overview of the critical elements needed to manage a large-scale, fast-moving infectious disease outbreak, and we suggest ways that the existing public health capacity might be strengthened to ensure an effective response to both natural and intentional disease outbreaks.  (+info)

A plague on your city: observations from TOPOFF. (5/535)

The United States Congress directed the Department of Justice to conduct an exercise engaging key personnel in the management of mock chemical, biological, or cyberterrorist attacks. The resulting exercise was called "TOPOFF," named for its engagement of top officials of the United States government. This article offers a number of medical and public health observations and lessons discovered during the bioterrorism component of the exercise. The TOPOFF exercise illuminated problematic issues of leadership and decision-making; the difficulties of prioritization and distribution of scarce resources; the crisis that contagious epidemics would cause in health care facilities; and the critical need to formulate sound principles of disease containment. These lessons should provoke consideration of future directions for bioterrorism planning and preparedness at all levels of government and among the many communities and practitioners with responsibilities for national security and public health.  (+info)

Risks and prevention of nosocomial transmission of rare zoonotic diseases. (6/535)

Americans are increasingly exposed to exotic zoonotic diseases through travel, contact with exotic pets, occupational exposure, and leisure pursuits. Appropriate isolation precautions are required to prevent nosocomial transmission of rare zoonotic diseases for which person-to-person transmission has been documented. This minireview provides guidelines for the isolation of patients and management of staff exposed to the following infectious diseases with documented person-to-person transmission: Andes hantavirus disease, anthrax, B virus infection, hemorrhagic fevers (due to Ebola, Marburg, Lassa, Crimean-Congo hemorrhagic fever, Argentine hemorrhagic fever, and Bolivian hemorrhagic fever viruses), monkeypox, plague, Q fever, and rabies. Several of these infections may also be encountered as bioterrorism hazards (i.e., anthrax, hemorrhagic fever viruses, plague, and Q fever). Adherence to recommended isolation precautions will allow for proper patient care while protecting the health care workers who provide care to patients with known or suspected zoonotic infections capable of nosocomial transmission.  (+info)

Infectious diseases: considerations for the 21st century. (7/535)

The discipline of infectious diseases will assume added prominence in the 21st century in both developed and developing nations. To an unprecedented extent, issues related to infectious diseases in the context of global health are on the agendas of world leaders, health policymakers, and philanthropies. This attention has focused both on scientific challenges such as vaccine development and on the deleterious effects of infectious diseases on economic development and political stability. Interest in global health has led to increasing levels of financial support, which, combined with recent technological advances, provide extraordinary opportunities for infectious disease research in the 21st century. The sequencing of human and microbial genomes and advances in functional genomics will underpin significant progress in many areas, including understanding human predisposition and susceptibility to disease, microbial pathogenesis, and the development new diagnostics, vaccines, and therapies. Increasingly, infectious disease research will be linked to the development of the medical infrastructure and training needed in developing countries to translate scientific advances into operational reality.  (+info)

Bioterrorism: implications for the clinical microbiologist. (8/535)

The specter of bioterrorism has captured the attention of government and military officials, scientists, and the general public. Compared to other sectors of the population, clinical microbiologists are more directly impacted by concerns about bioterrorism. This review focuses on the role envisioned for clinical laboratories in response to a bioterrorist event. The microbiology and clinical aspects of the biological agents thought to be the most likely tools of bioterrorists are presented. The historical background of the problem of bioterrorism and an overview of current U.S. preparedness planning, with an emphasis on the roles of health care professionals, are also included.  (+info)

In the event of a bioterror attack, rapidly estimating the size and time of attack enables short-run forecasts of the number of persons who will be symptomatic and require medical care. We present a Bayesian approach to this problem for use in real time and illustrate it with data from a simulated anthrax attack. The method is simple enough to be implemented in a spreadsheet.
On June 12,2003, the Alameda County Public Health Department and Sandia National Laboratories/CA jointly conducted an exercise that used a Weapons of Mass Destruction-Decision Analysis Center (WMD-DAC) bioterrorism attack simulation to test the effectiveness of the countys emergency response plan. The exercise was driven by an assumed release (in the vicinity of the Berkeley Marina), and subsequent spread, of a small quantity of aerosolized, weapons-grade anthrax spores. The simulation used several key WMD-DAC capabilities, namely: (1) integration with an atmospheric dispersion model to calculate expected dose levels in the affected areas, (2) a individual-tracking capability for both infected and non-infected persons as they made decisions, sought treatment, and received prophylaxis drugs, and (3) a user interface that allows exercise participants to affect the scenario evolution and outcome. The analysis of the countys response plan included documenting and reviewing the decisions made by
Terrorists are working to obtain chemical, biological, radiological and nuclear (CBRN) weapons and we believe that the threat of an attack is very real. While there is no way to predict precisely what may or may not happen, we do know that there are a number of practical steps you can take to protect your family members and your pets.. At a Health Canada conference in Ottawa, two years before the September 11 attacks, a scathing report detailing Canadas level of preparedness for a bioterrorism attack concluded, Canada is ill-equipped. A year earlier in 1999, the Canadian Security Intelligence Agency said its not a matter of if a bioterrorism attack will occur, but when.. Defence Research and Development allotted more than CAD $60 million in funding for anti-terrorist research projects, such as expanding the use of a Canada-made antidote used to protect against nerve agents, and finding ways to detect and combat nuclear, chemical, biological and radiation terrorist attacks. In February of ...
In February 2007, the Council extended the mandate of this Health Security Committee by three years.. AVAILABILITY AND STOCKPILING OF MEDICINES The bioterrorist attacks in the USA highlighted the fundamental importance of the availability of medicines in the EU and the capability of industry to make good any shortcoming in production and supply. A joint Commission/pharmaceutical industry task force was established in December 2001 to address issues of availability, production capability, storage and distribution capacity for medicines which could be used in the event of a bioterrorist attack.. National stockpiles In order to be able to cope with bioterrorist attacks, most Member States have stockpiled antibiotics at national level, or are in the process of doing so. Two of the larger Member States have offered to share stocks with other Member States. However, the majority of the other Member States did not wish to take up the offers made and the sharing scheme was not discussed further.. As the ...
The U.S. government is moving toward launching a new venture capital fund to help private companies develop vaccines and drugs that combat a future terrorist attack using biological agents.
Brucella, a Gram-negative bacterium, is classified as a potential bioterrorism agent mainly due to the low dose needed to cause infection and the ability to transmit the bacteria via aerosols. Goats/sheep, cattle, pigs, dogs, sheep and rodents are infected by B. melitensis, B. abortus, B. suis, B. canis, B. ovis and B. neotomae, respectively, the six classical Brucella species. Most human cases are caused by B. melitensis and B. abortus. Our aim was to specifically detect Brucellae with smooth lipopolysaccharide (LPS) using a highly sensitive monoclonal antibody (mAb) based immunological assay. To complement molecular detection systems for potential bioterror agents, as required by international biodefense regulations, sets of mAbs were generated by B cell hybridoma technology and used to develop immunological assays. The combination of mAbs most suitable for an antigen capture assay format was identified and an immunoassay using the Luminex xMAP technology was developed.
A biological attack by terrorists that could kill up to 30 million people is increasingly likely due to the ease with which pathogens can be
Source: Wall Street Journal, May 17, 2002. AFTERMATH OF TERROR. Civil-Liberties Issues Check Plans to Fight Bioterrorism. By MARILYN CHASE, Staff Reporter of THE WALL STREET JOURNAL. What would happen if another bioterrorist struck the U.S.?. Probably the same confusion, fear and uncoordinated response that happened during last falls anthrax attacks. Federal and state plans to respond to bioterrorism have run up against civil libertarians and a host of others who worry their rights will be trampled. Even some hospital groups have fought against plans for bioterror attacks because they dont want contagious patients in their facilities.. Just seven months ago, when anthrax was killing people and closing parts of the U.S. Postal Service and Washington D.C., nothing seemed more important than preparing for bioterror. A model law, drafted at the request of the Centers for Disease Control and Prevention, was rushed to state governments last fall to help their governors and public-health departments ...
President Bushs budget for 2006 cuts spending for a wide range of public health programs, including several to protect the nation against bioterrorist attacks and to respond to medical emergencies...His plan would also cut the budget of the Centers for Disease Control and Prevention by 9 percent, to $6.9 billion...the public health emergency fund of the centers, which helps state and local agencies prepare for bioterror attacks, would be cut 12.6 percent, to $1 billion ...
Scientists at the Scripps Research Institute and the University of Wisconsin have identified two small molecules with promising activity against neurotoxins produced by the Clostridium botulinum, a compound so deadly it has been labeled one of the six highest-risk bioterrorism agents by the Centers for Disease Control and Prevention.. Because of the high cost and limited applicability of currently available treatments, the newly identified compounds have the potential to fill the existing therapy gap and to provide protection against a bioterrorism attack using the toxin.. The study is being published the week of February 5 in an online edition of the Proceedings of the National Academy of Sciences.. Our study is an important milestone in the fight against biological terrorism, s. ...
On a CNN news broadcast in 2011, the CNN chief medical correspondent, Dr. Sanjay Gupta, weighed in on the American governments recent approach to bioterrorist threats. He explains how, even though the United States would be better fending off bioterrorist attacks now than they would be a decade ago, the amount of money available to fight bioterrorism over the last three years has begun to decrease. Looking at a detailed report that examined the funding decrease for bioterrorism in fifty-one American cities, Dr. Gupta stated that the cities wouldnt be able to distribute vaccines as well and wouldnt be able to track viruses. He went on to say that movie portrayals of global pandemics, such as Contagion, were actually quite possible and may occur in the United States under the right conditions.[47]. A news broadcast by MSNBC in 2010 also stressed the low levels of bioterrorism preparedness in the United States. The broadcast stated that a bipartisan report gave the Obama administration a ...
A bioterrorism attack involves the deliberate release of viruses, bacteria or other germs that are intended to cause illness or death in people, animals or plants.
Source: Los Angeles Times, May 1, 2002. COMMENTARY. Scientific Speed Is the Key in Fighting Bioterror. America should have a special lab and a system of molecular fingerprinting.. By SCOTT P. LAYNE and CLAIRE M. FRASER, Scott P. Layne is an associate professor of epidemiology at the UCLA School of Public Health. Claire M. Fraser is president of the Institute for Genome Research in Rockville, Md.. Its human nature: The United States fear of another biological attack is fading fast. But it shouldnt.. In Kandahar, U.S. forces have discovered an Al Qaeda laboratory that was to produce anthrax. And one of the Sept. 11 hijackers may have been treated in Florida for cutaneous anthrax last June. The threat of biological terrorism is real.. So far, our efforts have focused on improving the care of potential biological victims. And whether last years perpetrator, still at large, is a lone bio Kaczynski or an organized bio Bin Laden is somewhat beside the point. The primary issue is that the United ...
This Tuesday, Oct. 4, marks the 10th anniversary of the announcement of the first deaths in the 2001 anthrax-letter attacks, the first successful, fatal bioterrorist attack in American history on American soil. The anthrax attacks were recognized in the midst of the grief and disquiet that swept the United States after the Sept. 11 World […]
A national survey of 1,001 Australians found that most were concerned about a bioterrorist attack and were ill-informed about smallpox prevention and response. Since general practitioners were commonly identified as the initial point of care, they should become a focus of bioterrorism response planning in Australia.
New York Times President Bushs budget for 2006 cuts spending for a wide range of public health programs, including several to protect the nation against bioterrorist attacks and to respond to medical emergencies, budget documents show... ...Kim A. Elliott, deputy director of the Trust for Americas Health, a nonprofit advocacy group, said, Its robbing Peter to pay Paul when you build up the national stockpile at the expense of bioterrorism preparedness activities at the state and local level. View the full story (some sites require registration). ...
In the wake of the recent anthrax attacks, federal officials Tuesday began an inspection program of university facilities across the United States that conduct research on viruses and bacteria with the potential to be used in bioterror, a university official said.
As mandated in the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, CDCs BioSense program was launched in 2003 with the aim of e…
Target Capabiltities: Prevent: CBRNE Detection, Respond: Citizen Evacuation and Shelter In-place, Protect: Food and Agriculture Safety & Defense, Prevent: Information Sharing and Dissemination, Respond: Isolation and Quarantine, Respond: Mass Prophylaxis, Respond: Medical Surge, Common: Planning, Protect: Epidemiologic Surveillance and Investigation, Respond: Public Safety and Security Response, Common: Risk Management, Prevent: Law Enforcement Investigation and Intervention, Respond: Triage and Pre-hospital Treatment, Respond: WMD/Hazardous Materials Response and Decontamination ...
Many U.S. schools are not prepared for bioterrorism attacks, outbreaks of emerging infectious diseases or pandemics, despite the recent 2009 H1N1 influenza pandemic that resulted in more than 18,000 deaths worldwide, Saint Louis University researchers say. The study, led by Terri Rebmann, Ph.D., associate professor at SLUs Institute for Biosecurity, surveyed about 2000 nurses working in elementary, middle and high schools across 26 states. The findings reveal that only 48 percent of schools address pandemic preparedness and only 40 percent of schools have updated their plans . . .
Bioterrorism: Organizations and Methods - Bioterrorism organizations require a lot of money and technology to pull off a massive bioterrorism attack. Learn about bioterrorism organizations and methods.
Planning and preparing to provide care in the event of a bioterrorism attack or other emergency is a critical part of working in any healthcare environment. But planning is more than knowing where emergency supplies and exits are. Planning also involves ensuring that healthcare workers know how to keep safe, both physically and mentally. This includes having the families of healthcare workers be prepared for disasters. Studies have shown that providing care to disaster victims is impaired when healthcare workers are concerned about their own families safety.. This program is designed to help healthcare workers prepare themselves at work, at home and in the community at large, to respond to bioterrorism and other emergencies.. ...
After 2005, the department implemented the model throughout the state, although the number of human cases and reported dead birds, along with the models prediction rates, dropped sharply.. In 2007 Carney enrolled as a masters student at Yale and adapted the DYCAST model to track dengue fever in Brazil, using a version of the software that his CUNY collaborators had converted to an open-source platform. With the specific parameters of that disease, DYCAST was able to predict its spread in the city of Riberão Preto in Brazil, Carney said, citing unpublished data.. Carney has continued his analysis and development of DYCAST and dengue at Brown, where he is a doctoral student of ecology and evolutionary biology. He said the software at its core has potential to be adapted as an early warning system for other infectious diseases or even bioterrorism attacks.. In addition to Carney, other authors on the paper include Sean Ahearn and Alan McConchie of CUNY (McConchie is now at the University of ...
Many U.S. schools are not prepared for bioterrorism attacks, outbreaks of emerging infectious diseases or pandemics, despite the recent 2009 H1N1 influenza pandemic that resulted in more than 18,000 deaths worldwide, Saint ...
Although new drug development usually focuses on clinical and preclinical research, moving innovative products from clinical testing to market mainly involves overcoming manufacturing capabilities and production challenges. Ensuring access to consistently high-quality critical vaccines and therapies needed to counter bioterrorism attacks is a topic frequently debated. Product shortages are leading to policies that expand US drug and vaccine manufacturing and ensure that US regulatory and healthcare policies avoid erecting roadblocks to high-quality drug production.
Distributed 11/07/03. Although theres not an imminent danger, some scientists say a widespread disease or bioterrorism attack could wipe out significant portions of the U.S. farm animal population.. The countrys genetic resources support a host of animal industries, and without some action to preserve them, those resources are at risk, according to Dr. Harvey Blackburn, director of the U.S. Department of Agricultures National Animal Germplasm Program.. Speaking to a group of animal scientists at the LSU AgCenter Tuesday (Nov. 4), Blackburn said his program was created by Congress because of concern that some animal industries dependence on one or two breeds of a species could pose long-term problems if other genetic material isnt available. He cited as examples the leghorn chicken and Holstein dairy breed, which currently dominate the poultry and milk industries.. The National Animal Germplasm Program (NAGP) is patterned after the well-established USDA National Plant Germplasm System, which ...
We have had the better part of a year to get ready for swine flu. And yet, the response to the pandemic H1N1 outbreak has been lousy, bioethicist Art Caplan says. What would happen if there were a bioterrorism attack or a truly deadly pandemic?
Inspired by recent advances in genetics, Bay Area scientists are dialing up our inner strength to survive a bioterrorism attack. Labs at Stanford and UC San Francisco were recently selected by the Department of Defense to use a modified form of CRISPR gene editing to boost our body
Immunostimulatory oligonucleotide (ISS-ODN) used as adjuvants are commonly modified with phosphorothioate (PS). the transient effects from a PO TLR-9 agonist may be beneficial for protection in a bacterial bioterrorism attack by delaying the onset of systemic contamination without the induction of a cytokine CCT239065 syndrome. activity due to a short half-life [11 12 Their shorter half-life may limit their potency but also their potential toxicity. However several studies have shown that specific modifications of PO ISS-ODN improve their efficacy as adjuvants. Examples of bioeffective alterations include conjugation of the PO ISS-ODN to a hexameric deoxyriboguanosine (3′dG6) at the 3′-end [13] and chemically linking two PO ISS-ODN via their 3′ ends. We recently reported the structural requirements for PO ISS-ODN to penetrate cells and to elicit a functional TLR-9 response [14 15 Serial selection from a random library and optimal structural modifications resulted in the generation of a PO ...
It will be too late for Congress to act after bioterrorism attack is launched, op-ed, Lubbock Avalanche Journal (Saturday, Sept. 22, 2001 ...
Despite the terrorist attacks of September 11, the anthrax mailings, media coverage and a proliferation of programs about bioterrorist agents, a survey conducted in 2002 found that although four out of five physicians were willing to care for victims of a bioterrorist attack, only one out of five felt well prepared for such a role.
More than 1,100 laboratory incidents involving bacteria, viruses and toxins that pose significant or bioterror risks to people and agriculture were reported to federal regulators during 2008 through 2012,
Sure, bug swarms can spread nasty things, but using them to unleash bioterror isnt as easy as they say, Robert Roy Britt writes in LiveScience. One expert said in the Telegraph today that dispersing... Science News Summaries. | Newser
General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and ...
General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and ...
Since September 11th, the threat of a bioterrorist attack--massive, lethal, and unpreventable--has hung in the air over America. Bracing for Armageddon? offers a vividly written primer for the general reader, shedding light on the science behind potential bioterrorist attacks and revealing what could happen, what is likely to happen, and what almost certainly will not happen.
Laura H. Kahn is the author of One Health and the Politics of Antimicrobial Resistance, published in 2016 by Johns Hopkins University Press. A general internist who began her career in health care as a registered nurse, Kahn is a research scholar with Princeton Universitys Program on Science and Global Security. Her expertise is in public health, biodefense, and pandemics. In 2009, she published Whos In Charge? Leadership during Epidemics, Bioterror Attacks, and Other Public Health Crises. Princeton University awarded her undergraduate course Hogs, Bats, and Ebola: An Introduction to One Health Policy a 250th Anniversary Fund award for Innovation in Undergraduate Education. In 2016, the American Veterinary Epidemiology Society awarded her their highest honor, the K.F. Meyer-James H. Steele Gold-Headed Cane Award, for her work on One Health. ...
have suggested that both modeling principles and basic beliefs are important in discussing how we should prepare for possible smallpox terrorist attacks.1 Eichner and Schwehm (ES) amplify these aspects.2 ES focus on surveillance as a prevention tool. In the ES world, any contact under surveillance would be prevented from transmitting further infections at the moment the contact becomes infectious, irrespective of the total number of contacts under watch. Thus, surveillance becomes equivalent to quarantine (which was considered in my earlier modeling work3,4).. Presuming that 75% of transmission from infected contacts can be prevented in this manner strikes ES as reasonable, but strikes me as extremely optimistic in the event of a bioterror attack. The potential for societal chaos in the wake of a smallpox attack should not be underestimated. Nonetheless, combined with the additional assumptions in their Figure 2 (that 90% of the population is susceptible and that isolation of symptomatic ...
Buy Antirobe Online! Antirobe injection is also sometimes used to treat malaria (a serious infection spread by mosquitoes in some parts of the world) and to prevent infection in people who are having certain types of surgery. Antirobe injection is also sometimes used to treat anthrax (a serious infection that may be spread as part of a bioterror attack) and toxoplasmos...
Buy Basocin Online! Basocin injection is also sometimes used to treat malaria (a serious infection spread by mosquitoes in some parts of the world) and to prevent infection in people who are having certain types of surgery. Basocin injection is also sometimes used to treat anthrax (a serious infection that may be spread as part of a bioterror attack) and toxoplasmosis...
Buy Albiotin Online! Albiotin injection is also sometimes used to treat malaria (a serious infection spread by mosquitoes in some parts of the world) and to prevent infection in people who are having certain types of surgery. Albiotin injection is also sometimes used to treat anthrax (a serious infection that may be spread as part of a bioterror attack) and toxoplasmos...
Buy Clinda Online! Clinda injection is also sometimes used to treat malaria (a serious infection spread by mosquitoes in some parts of the world) and to prevent infection in people who are having certain types of surgery. Clinda injection is also sometimes used to treat anthrax (a serious infection that may be spread as part of a bioterror attack) and toxoplasmosis (...
WASHINGTON - More than five years after the Sept. 11 attacks, the government cannot show how the $5 billion given to public health departments has better prepared the country for a bioterrorism
By the editor Natural News. People ask me, Dave, what is the endgame with the globalists? It is unquestionably, bioterrorism. I have a friend, who is retired from FEMA and his specialty was counter-bioterrorism. Some of my present sources say the same. MOST OF MY KEY AND HIGH RANKING SOURCES SAY THAT WE ARE BEING SET UP FOR A MASSIVE BIOTERROR ATTACK AND THE FINAL CHAPTER OF THIS ATTACK WILL BE THE DEADLY EFFECTS OF VACCINES THAT BROUGHT TO BEAR AGAINST THE MANUFACTURED ATTACKS. THE ADJUVANTS AND VACCINES ARE DEADLY OVER TIME AND THEY REFLECT THE QUOTED REALITY OF KEY GLOBALISTS THROUGH THE YEARS. TAKE THE FOLLOWING AS A DECLARATION OF WAR AGAINST TRANSHUMANISM-LOVING GLOBALISTS.. For the past four years, I have researched the following question: Is there a deliberate attempt on the part of the global elite to eliminate a substantial portion of humanity through the use of a bioengineered diseases and viruses and the more deadly accompanying vaccines?. As with any murder plot, whether it be a ...
A long-awaited US government policy on biological research that could be used for terrorism or other nefarious purposes is little changed from a draft released 19 months ago, despite receiving 38 comments from institutions and researchers concerned that it goes either too far or not far enough. The centrepiece of the policy, released on 24 September, is a set of guidelines for researchers working on 15 specific pathogens or toxins. But the rules do not regulate experiments that engineer pathogens not on the list to make them more deadly - so-called gain-of-function research. Officials from the White House and US National Institutes of Health (NIH) say the government will be addressing these concerns in coming weeks.. The White House released its first draft policy on dual-use research of concern, or DURC, in February 2013. The policy requires researchers at institutions that receive funding from the US government and are working with one of 15 specific pathogens or toxins to notify their ...
The U.S. Defense Department is set to alter the priorities of a 5-year-old program that has made little progress toward developing countermeasures for pathogens that might be genetically tweaked for an act of bioterrorism, despite $1 billion in funding, the Boston Globe reported yesterday (see GSN, Nov. 11, 2010).. Independent research entities funded under the Defense Threat Reduction Agencys Transformational Medical Technologies Initiative were unable to overcome key obstacles in genetic research, officials and biological terrorism experts said. Of more than 50 studies funded by the program and carried out by more than 100 university laboratories, pharmaceutical groups and biotechnology firms, only two drugs of potential use have emerged, the Globe reported. Preliminary clinical trials of the treatments remained a distant possibility.. Were years away from any reasonable [Food and Drug Administration] certification, let alone production, said a Defense Department contractor with ties to ...
Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies. Evaluates the federal governments role and performance, and offers recommendations for improving readiness.
This paper provides an overview of the U.S. regulatory framework governing genetic biocontrol efforts for invasive fish. Genetic biocontrol refers to the intentional release of genetically modified organisms (GMOs) into the environment to control a target population of a non-native species. The terms genetically modified and genetically engineered are often used interchangeably, despite the sc ...
This paper provides an overview of the U.S. regulatory framework governing genetic biocontrol efforts for invasive fish. Genetic biocontrol refers to the intentional release of genetically modified organisms (GMOs) into the environment to control a target population of a non-native species. The terms genetically modified and genetically engineered are often used interchangeably, despite the sc ...
The Deputy National Security Advisor is a member of the Executive Office of the President of the United States and the United States National Security Council, serving under the Presidents National Security Advisor. Among other responsibilities, the Deputy National Security Advisor often serves as Executive Secretary to the National Security Council Principals Committee, and as chairman of the National Security Council Deputies Committee. The role changes according to the organizational philosophy and staffing of each White House and there are often multiple deputies to the National Security Advisor charged with various areas of focus.[1][2] The position is currently being held by Charles Kupperman since 2019. ...
The Bioterrorism Response Act also directs the HHS Secretary to promulgate regulations to establish and enforce safety and security procedures for the possession and use of select agents and toxins, including measures to ensure proper training and appropriate skills to handle such select agents and toxins. See generally, 42 C.F.R. Part 73. The U.S. Department of Agriculture select agents and toxins regulations are found at 7 C.F.R. Part 331 and 9 C.F.R. Part 121. Pursuant to subtitle B of title II of the Public Health Security and Bioterrorism Preparedness and Response Act of 2002 (the Agricultural Bioterrorism Protection Act), the USDA Secretary has established a list of biological agents and toxins which have the potential to pose a severe threat to animal and plant health, or to animal or plant products (See 7 USC § 8041). This list is found in section 3 (PPQ select agents and toxins) of Part 331 and in section 3 (VS select agents and toxins) and section 4 (Overlap select agents and toxins) ...
The predecessor to the National Security Council was the National Intelligence Authority (NIA) which was established by President Harry S. Trumans Executive Letter of 22 January 1946 to oversee the Central Intelligence Group, the CIAs predecessor. The NIA was composed of the Secretary of State, Secretary of War, Secretary of the Navy, and the Chief of Staff to the Commander in Chief. The National Security Council was created in 1947 by the National Security Act. It was created because policymakers felt that the diplomacy of the State Department was no longer adequate to contain the USSR in light of the tension between the Soviet Union and the United States.[1] The intent was to ensure coordination and concurrence among the Army, Marine Corps, Navy, Air Force and other instruments of national security policy such as the Central Intelligence Agency (CIA), also created in the National Security Act. In 2004, the position of Director of National Intelligence (DNI) was created, taking over the ...
Washington Post A decade after envelopes containing anthrax terrorized the nation and alerted officials to the need to protect against bioterrorism, significant gaps remain in the nations capacity to respond to a bioterrorism attack, according to an analysis released Thursday.. Although the anthrax attacks triggered an unprecedented attempt to bolster the nations preparedness, and significant improvements have been made, much more work remains to be done, according to the analysis by the Trust for Americas Health and the Robert Wood Johnson Foundation, two private nonprofit, nonpartisan research groups.. View the full story (some sites require registration). ...
When Edward Snowden leaked Americas extensive surveillance practices, it didnt just impact American citizens. It changed the way people all over the world thought about their data privacy and how it impacts national security. The increased focus on data privacy hasnt only affected governments either. It has shed new light onto the data collection practices of businesses. Many have called into question how businesses should handle data, with national security matters (Apples refusal to unlock an iPhone is a great example) and data breaches creating big discussions on the subject. A fine line People feel just as negatively about the collection of their personal data today as they did in 2013. However, despite the negative associations, people are becoming more willing to let their data be collected if it will protect national security. Astonishingly, only 20% of people surveyed in 2016 dont support the use of personal data to protect national security. This is a major decrease from the 42% who were
Statement by NSC Spokesman Mike Hammer on National Security Advisor General Jim Jones Travel to France, Belgium, and India, July 11-16. National Security Advisor General Jim Jones will travel to Paris, Brussels, and New Delhi from July 11 to 16. On July 12 and 13, General Jones will consult with French officials, NATO Secretary General Rasmussen, and other allies in Paris and Brussels regarding Afghanistan, Middle East, Iraq, Iran, and preparations for NATOs fall summit in Lisbon. From July 14 to 16, General Jones will be visiting India at the invitation of his counterpart, Indian National Security Advisor Shivshankar Menon. During his visit to New Delhi, the General will meet with National Security Advisor Menon and other senior Indian officials to discuss a full range of subjects key to the strategic partnership we are developing with India, including counter-terrorism cooperation, regional security, defense cooperation, and export controls. General Jones will also have an opportunity begin ...
National Security Advisor Tom Donilon hosted Iraqi National Security Advisor Falah al-Fayyadh at the White House today. They held discussions to follow up on the productive Secure Video Teleconference last week between President Obama and Prime Minister Maliki. The two national security advisors reaffirmed the common vision of a broad, deep strategic partnership between the United States and Iraq as embodied in the Strategic Framework Agreement. The two held a far-reaching discussion of the elements of a fully normalized relationship between Iraq and the United States, including education, investment, and security. And they committed to develop additional mechanisms to establish a continuous strategic dialogue between the United States and Iraq.. ...
State and Local Governments must be invited by DHS to apply. DHS will invite governmental organizations to apply for continuation funding under this FOA. The BioWatch Program is a cornerstone of the Department of Homeland Securitys (DHS) comprehensive strategy for countering biological terrorism. The BioWatch Program is an early warning system that is designed to detect the intentional release of select aerosolized biological agents. The BioWatch Programs mission is to provide and maintain a continuous bio-terrorism air monitoring system in metropolitan areas and coordinate with state and local public health communities to prepare for and respond to a bioterrorist event. This mission is accomplished by serving as an early warning system which enhances the security of jurisdictions by providing the needed time to execute their comprehensive concept of operations plans to counter biological terrorism. The Biowatch Program is a critical part of an ongoing national effort to build and sustain ...
Overview of the most pressing biosecurity issues facing the world today. Guest lecturers have included former Secretary of State Condoleezza Rice, former Special Assistant on BioSecurity to Presidents Clinton and Bush Jr. Dr. Ken Bernard, Chief Medical Officer of the Homeland Security Department Dr. Alex Garza, eminent scientists, innovators and physicians in the field, and leaders of relevant technology companies. How well the US and global healthcare systems are prepared to withstand a pandemic or a bioterrorism attack, how the medical/healthcare field, government, and the technology sectors are involved in biosecurity and pandemic or bioterrorism response and how they interface, the rise of synthetic biology with its promises and threats, global bio-surveillance, making the medical diagnosis, isolation, containment, hospital surge capacity, stockpiling and distribution of countermeasures, food and agriculture biosecurity, new promising technologies for detection of bio-threats and ...
Overview of the most pressing biosecurity issues facing the world today. Guest lecturers have included former Secretary of State Condoleezza Rice, former Special Assistant on BioSecurity to Presidents Clinton and Bush Jr. Dr. Ken Bernard, Chief Medical Officer of the Homeland Security Department Dr. Alex Garza, eminent scientists, innovators and physicians in the field, and leaders of relevant technology companies. How well the US and global healthcare systems are prepared to withstand a pandemic or a bioterrorism attack, how the medical/healthcare field, government, and the technology sectors are involved in biosecurity and pandemic or bioterrorism response and how they interface, the rise of synthetic biology with its promises and threats, global bio-surveillance, making the medical diagnosis, isolation, containment, hospital surge capacity, stockpiling and distribution of countermeasures, food and agriculture biosecurity, new promising technologies for detection of bio-threats and ...
Since October 3, 2001, CDC and state and local public health authorities have been investigating cases of bioterrorism-related anthrax. This report updates findings as of October 31, and includes interim guidelines for the clinical evaluation of pers ...
The New York Times publishes an article by Sheryl Gay Stolberg entitled, Some Experts Say US Is Vulnerable to a Germ Attack. The article claims that the US is inadequately prepared to confront bioterrorist attacks, according to a broad range of health experts and officials. The nation must develop new vaccines and treatments, they say, but it must also fortify its fragile public health infrastructure, the first line of defense in detecting and containing biological threats. It further notes that since 9/11, much of the discussion about bioterrorism has centered on a shortage of antibiotics and vaccines. But the bigger problem, officials agree, is a lack of basic public health infrastructure and preparedness that could thwart a terror attack or limit its effects. Doctors are poorly trained to recognize symptoms of infection with possible biological weapons, like plague and anthrax, which can resemble the flu. Asha George, an expert on biological warfare, says, We are not going to have a ...
The New York Times publishes an article by Sheryl Gay Stolberg entitled, Some Experts Say US Is Vulnerable to a Germ Attack. The article claims that the US is inadequately prepared to confront bioterrorist attacks, according to a broad range of health experts and officials. The nation must develop new vaccines and treatments, they say, but it must also fortify its fragile public health infrastructure, the first line of defense in detecting and containing biological threats. It further notes that since 9/11, much of the discussion about bioterrorism has centered on a shortage of antibiotics and vaccines. But the bigger problem, officials agree, is a lack of basic public health infrastructure and preparedness that could thwart a terror attack or limit its effects. Doctors are poorly trained to recognize symptoms of infection with possible biological weapons, like plague and anthrax, which can resemble the flu. Asha George, an expert on biological warfare, says, We are not going to have a ...
The overriding question is whether the U.S. is ready for a bioterror attack. The answer could well rely on the other question of what bio-agent and whats the source? In 1991, 40,000 Russian scientists dispersed throughout the world, with knowledge of what the U.S.S.R. was doing in chemical and biological weapons. The question is to whom did they sell their knowledge? Some believe former Soviet scientists sold technology to countries like Iran, Syria, and North Korea. Lurking is the spectre of al-Qaeda, a group that the Pentagon says continues to pursue biological weapons.. Another scenario is an outbreak of a pandemic. How would the U.S. deal with an infectious disease outbreak? The picture, despite reassurances, is not pretty. Until now, the U.S. has experienced two major biological attacks.. In 1984, the Bhagwan Shree Rajneesh and his followers attempted to take over the town of Dalles, Oregon by contaminating salad bars in the town. In 2001, there was the as yet unsolved mystery of the ...
From December 02-05, 2014, PILDAT, in partnership with the CPA UK, organised a Study Visit of a multi-party delegation of five senior Members from the Parliament of Pakistan. The Study Visit focussed on the internal structures and ethos of UK political parties and how they develop their positions on national security issues in the UK.The programme was designed to give the delegation a deeper understanding of the UK national security framework, including the role of political parties in formulating the UK national security strategy along with the parliamentary oversight of defence related spending and intelligence activities. The programme also addressed the issue of the changing face of national and international security. ...
Quick update from the The Washington Post newsroom: starting July 1, I will join the foreign desk as the world and national security producer. Anup Kaphle (who has been the world/national security web editor on the Universal News Desk) and I will be moving from the UND to work directly with the world and national security teams.. Ive had a great experience working with the health, science, environment and wellness reporters and editors since I joined the Post in December and am very excited at this new opportunity be a full member of the foreign editing team - truly integrated with the section.. Stay tuned!. ...
The mission of the Lint Center for National Security Studies is to foster and further the educational development and opportunities for the next generation of Americas Counterintelligence and National Security Workers. The Center focuses on empowering individuals, enhancing the study of national security issues, and enabling emerging leaders to be mentored by established current-and-former industry experts.
The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. The report provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The report recommends that all unclassified data on bioterrorism agent studies -- including unclassified, unpublished data from U.S. Army Medical Research ...
An anthrax bioterrorism attack in a transportation hub will require the use of various decontamination approaches, including fogging of sporicidal liquids.
Since the last report (1), six new anthrax cases have been reported. Three of these cases have occupational exposures similar to previously reported cases (1). A fourth case occurred in a mail handler at a facility not previously linked to cases but that receives mail from a facility at which cases have occurred previously. Two new cases have no discernable epidemiologic link with anthrax cases previously reported or sites that are associated with known cases. These new cases suggest that anthrax exposure has occurred or is continuing to occur through means that cannot be ascribed to known contaminated letters or the paths these letters took through the mail service. The public health response to these new anthrax cases will evolve based on ongoing epidemiologic and criminal investigations. Because exposures are being intentionally perpetrated, public health authorities must be vigilant for the appearance of new cases in previously unaffected populations. Prompt data sharing between law ...
Title: PowerPoint Presentation Author: dsmith3 Last modified by: Vivien Maier Created Date: 5/8/2003 5:54:42 PM Document presentation format: On-screen Show – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 7bd45e-Y2U1Y
The Public Health Security and Bioterrorism Preparedness and Response Act of 2002 (Public Law 107-188; June 12, 2002) requires that the United States improve its ability to prevent, prepare for, and respond to acts of bioterrorism and other public health emergencies that could threaten either public health and safety or American Agriculture. It necessitates that individuals possessing, using, or transferring agents or toxins deemed a severe threat to public, animal or plant health, or to animal or plant products notify either the Secretary of the Department of Health and Human Services (HHS) or the Secretary of the Department of Agriculture (USDA). In accordance with the Act, implementing regulations detailing the requirements for possession, use, and transfer for select agents and toxins were published by HHS (42 CFR Part 73). Registration of an entity requires that an Application for Laboratory Registration for Possession, Use, and Transfer of Select Agents and Toxins (APHIS/CDC Form 1) ...
FY10-27. OAK RIDGE, Tenn.-John L. Crapo, CHP, has been named the new associate director for readiness in ORAUs National Security and Emergency Management Programs.. In his new role, Crapo will be responsible for planning, organizing, directing and scheduling all management activities associated with ORAUs support to the U.S. Department of Energy (DOE) Office of Emergency Responses counterterrorism, counter-proliferation and emergency management fields. He will also provide strategic insight into DOEs program goals and plans as they pertain to the emergency response mission.. John has a strong background in radiological consequence management and regulatory compliance, said Dave Hackemeyer, vice president and director for ORAUs National Security and Emergency Management Programs. He will do a great job, and he will ensure our support to DOE meets and exceeds expectations.. Before joining ORAU in 2007, Crapo served nearly 20 years in the U.S. Navy as a health physicist. He received a ...
We live in an era of mass surveillance. Private companies monitor our comings and goings, and ad-supported cloud services record and mine our online activities. At the same time, governments have been conducting extensive surveillance in the name of national security. To a large extent, citizens and lawmakers have accepted loss of privacy in exchange for increased security. Can computing technology promote both personal privacy and national security? Panelists will explore how state-of-the-art cryptography, security, networked systems, and data-management technology might enable government agencies to acquire actionable, useful information about legitimate targets of investigation without intruding upon the electronic activity of innocent parties. They will also address the need to use laws and policies in conjunction with technology to hold government agencies accountable for proper use of private information.. ...
The minor in National Security Studies is designed for students who are interested in the historical, political, cultural, ethical, and legal dimensions of national security policy.. ...
If ever there were a news item worthy of the Cool stuff! tag, its the list of Foreign Policy Next Generation Leaders from the Asian American and Pacific Islander (AAPI) community recently published by The Diversity in National Security Network and New America. The list is an impressive collection of talent as a whole, but what were obviously most interested in here is the fact that its positively larded with Fletcher alumni! Theres Jimmy Antia, a national security specialist with the Institute of Security Governance, Grace Choi, the director of policy in the NYC Mayors office, director for Afghanistan strategy and policy Hila Hanif, of the Office of the Secretary of Defense, and Michelle Kwan, a former Olympian currently working on the Biden 2020 presidential campaign. The list isnt limited to alumni, either. Current Fletcher student Tashi Chogyal, who came to Fletcher after stints at USAID, the US Department of Justice, the Center for American Progress, and the 2012 Obama re-election ...
The Citizens Report on the Performance of the Parliamentary Committee on National Security covers the period of March 16, 2012 to March 15, 2013. Prepared by PILDAT, the report closely examines the publicly-available data on the work of the Parliamentary Committee which was formed as a result of a joint Parliamentary resolution in November 2008. This report has been prepared under the overall objective of strengthening Parliamentary oversight on defence and national security in Pakistan. This report is a continuation of the analysis prepared by PILDAT for the past 4 years. PILDAT is mindful of the fact that the democratic institutions like the Parliament and Parliamentary committees have not developed over the years due to repeated military interventions and long spells of autocratic or semi-autocratic regimes led by military. This citizens review, therefore, is meant to assist the Parliament in its oversight functions. The objective of the report is not to offer a critique of the work of the ...
The International Financial Aid Center offers financial aid, college scholarships, grants and awards search for international students studying abroad. The International Financial Aid Center scholarship search tool provides you with access to awards from all across the globe. Boren Scholarships, an initiative of the National Security Education Program, provide unique funding opportunities for U.S. undergraduate students to study less commonly taught languages in world regions critical to U.S. interests, and underrepresented in study abroad, including Africa, Asia, Central and Eastern Europe, Eurasia, Latin America, and the Middle East. The countries of Western Europe, Canada, Australia, and New Zealand are excluded. Boren Scholars represent a vital pool of highly motivated individuals who wish to work in the federal national security arena. In exchange for funding, Boren Scholars commit to working in the federal government for at least one year after graduation.
While American national security policy has grown more interventionist since the Cold War, Washington has also hoped to shape the world on the cheap. Misled by the stunning success against Iraq in 1991, administrations of both parties have pursued ambitious aims with limited force, committing the countrys military frequently yet often hesitantly, with inconsistent justification. These ventures have produced strategic confusion, unplanned entanglements, and indecisive results. This collection of essays by Richard K. Betts, a leading international politics scholar, investigates the use of American force since the end of the Cold War, suggesting guidelines for making it more selective and successful. Betts brings his extensive knowledge of twentieth century American diplomatic and military history to bear on the full range of theory and practice in national security, surveying the Cold War roots of recent initiatives and arguing that U.S. policy has always been more unilateral than liberal ...
When exploring medical privacy issues, its very useful to have an overview of the laws that affect control and privacy of medical information. We encourage you to read our legal overview. The government has many options for obtaining your medical records on the grounds of national security. And if your medical records are swept up in a national security investigation, you
News breaks this morning that the NSA has the ability to monitor 75% of the nations internet traffic at once. They can watch what 75% of Americans are doing at any one time online. Think on that for a moment.. We have already learned that they can monitor your cell phone. They can get access to your individual online browsing history via your internet service provider, and read your emails. Now we learn that they can watch over three-quarters of the nations internet traffic at the drop of a hat.. This has gone far beyond national security.. On Coffee & Markets yesterday Congressman Bob Goodlatte, Chairman of the House Judiciary Committee, said it is time for more transparency of the NSAs monitoring efforts and called for better oversight of these programs. Both of those suggestions are great first steps to reining in the NSA, but there is more that needs to be done.. In the name of national security, has become the most overused and hollow phrase in Washington. It seems any activity can be ...
Wednesday, April 11th, 2018 Nadia Schadlow is third national security official to leave post since John Bolton became national security adviser. ...
He is also remembered for his friendship with Tampa socialite Jill Kelley, helping get her named an honorary ambassador to the coalition of some 50 nations at CentCom. Emails to Kelley led to the downfall of then-CIA director David Petraeus - another former CentCom leader also mentioned as a replacement for short-timer Flynn.. • • •. The national security adviser is the presidents top confidante on national security and foreign policy. Considering the pledge by President Donald Trump to destroy the so-called Islamic State jihadi group, some who know Harward call him an ideal choice for the job.. Given the challenges, his background as special operator, his familiarity with the region and his experience at CentCom, my gut feeling is he would be pretty good, said Mike Jones, a retired Army major general living in Tampa who was CentCom chief of staff in Harwards first year there.. Harward, Jones said, was the guy who could work the things the commander wanted him to, really understanding ...
WASHINGTON - President Donald Trump has announced Lt. Gen. H.R. McMaster as the new national security adviser, and Gen. Keith Kellogg remains the National Security Council chief of staff. The President made the announcement at his Mar-a-Lago resort. President Trump called McMaster a man of tremendous talent and tremendous experience. McMaster replaces retired Gen. Michael […]
The National Security angle could have the most powerful impact on public sentiment and senate votes, diminishing the political framing and enhancing the Rule of law/Oath of Office issue, seen through the lens of National Security ...
The battle between anti-Trump careerists within the U.S. intelligence community and the commander-in-chief is getting more serious by the day. On Wednesday, in the aftermath of the resignation of Trumps national security advisor, Michael Flynn - thought to be the first of many Trump national security team casualties to come - former NSA analyst and ...
national security Admissions, Courses and Scholarships 2021 HelpToStudy.com 2022 - Expert college reviews and admission help with application and essays. Apply national security soon.
Description: The September 11th attack and subsequent intentional release of anthrax spores via the U.S. postal system have focused policymakers attention on the preparedness and response capability of the nations public health system. The anthrax attacks put a tremendous strain on the U. S. public health infrastructure, an infrastructure that many experts argue has been weakened by years of neglect and under-funding. To better understand the preparedness gaps that exist, as well as the disparate functions and agencies that define public health in this country, the Congressional Research Service (CRS), in conjunction with George Washington Universitys National Health Policy Forum (NHPF), convened a seminar on October 26, 2001, entitled, The U.S. Health Care System: Are State and Local Officials Prepared for Bioterrorism? How Should the Federal Government Assist? ...
In the aftermath of the World Trade Center attack on September 11, 2001, there have been several bioterrorism attacks in the continental United States, ...
The first evening of the #MoBE17 meeting was a reception, with a fabulous keynote talk by Ed Yong mainly focused on Science Communication. Ed had a number of tips for interacting with journalists and thinking about how we present stories instead of facts. The quote of the evening was surely you cannot replace a feeling with a fact. Jonathan Eisen created a Storify of Day 1 which can be found here.. Started the next day with an introduction by Paula Olsiewski, giving her perspective on the field as a funder. The program grew out of work on an earlier program looking at preventing bioterrorism attacks, they soon discovered that little was known about the normal indoor microbiome. She gave us the history of the program; recruiting senior researchers early, getting buy-in from early career researchers, building collaborations across fields, engaging the public, and obtaining other support for the field.. Sue Lynch gave the Keynote talk today, talking about her groundbreaking work on childhood ...
MADISON - In this time of the chronic threat of terrorism and the possibility of war with an adversary who may be armed with biological weapons high on the wish list of security agencies and battlefield commanders is a quick and easy way to detect the presence of dangerous biological agents. Now with the help of a novel diamond film developed by chemists at the University of Wisconsin-M,Diamond,Film,May,Enable,Critical,New,Sensors,For,Bioterror,biological,advanced biology technology,biology laboratory technology,biology device technology,latest biology technology
Following the high-profile laboratory incidents involving select agents and toxins that occurred at federally regulated laboratories, the National Science and Technology Council established a Fast Track Action Committee on the Select Agent Regulations(FTAC-SAR) under the Subcommittee on Biological Defense Research and Development of its Committee on Homeland and National Security. The FTAC and the White House Office of Science and Technology Policy convened two listening sessions and published a Request for Public Comment in the Federal Register to engage input into how the Select Agent Regulations (SAR) have impacted science, technology, and national security in the United States. Based on this input, the FTAC published the Fast Track Action Committee Report that offered recommendations for FSAP program improvement.. Recommendation #6 (Inventory Control Requirements) The FTAC recommends retaining requirements to maintain inventories of samples containing biological select agents and toxins, ...
UCLA scientists have discovered how the deadly Nipah virus infiltrates human cells to cause encephalitis. Designated as a potential bioterrorism agent by the National Biodefense Research Agenda, the virus exploits a protein essential to embryonic development to enter cells and launch its attack.
Traditional laboratory biosafety guidelines have emphasized use of optimal work practices, appropriate containment equipment, well-designed facilities, and administrative controls to minimize risks of unintentional infection or injury for laboratory workers and to prevent contamination of the outside environment (1). Although clinical and research microbiology laboratories might contain dangerous biologic, chemical, and radioactive materials, to date, only a limited number of reports have been published of materials being used intentionally to injure laboratory workers or others (2--7). However, recently, concern has increased regarding possible use of biologic, chemical, and radioactive materials as terrorism agents (8,9). In the United States, recent terrorism incidents (10) have resulted in the substantial enhancement of existing regulations and creation of new regulations governing laboratory security to prevent such incidents. The Public Health Security and Bioterrorism Preparedness and ...
In order to discuss Biosafety, it is important to understand the concept. Biosafety refers to the prevention of unintentional outbrakes of pathogens, toxins due to accidents or lack of knowledge. It is important to distinguish the concept of Biosafety from Biosecurity. Biosecurity deals with issues of theft, misuse, diversion or any intentional release of dangerous biological material or pathogens (Schmidt, Chapter 6: Do I undestand what I can create? Biosafety issues in synthetic biology, 2009). Although Biosecurity is an important concept, especially when dealing with issues such as bioterrorism and national security, its mostly managed by the government and international regulatory agencies. The scientific community can do little or nothing with respect to Biosecurity in the same manner it can only make small contributions to solve problems such as terrorism or organized crime. Most of the times, researchers can limit themselves to denounce irregularities they detect so that a law ...
In the latter case, or if a nation-state uses it clandestinely, it may also be considered bioterrorism. Biological warfare and ... In 2015, to combat the threat of bioterrorism, a National Blueprint for Biodefense was issued by the Blue-Ribbon Study Panel on ... The growing threat of biowarfare agents and bioterrorism has led to the development of specific field tools that perform on-the ... Though a verification system can reduce bioterrorism, an employee, or a lone terrorist having adequate knowledge of a bio- ...
"Smallpox > Bioterrorism". Centers for Disease Control and Prevention. December 19, 2016. Retrieved May 21, 2022. Today, there ...
After the September 11 attacks in 2001, many governments began building up vaccine stockpiles again for fear of bioterrorism. ... ISBN 978-1-59102-722-5. "Smallpox > Bioterrorism". U.S. Centers for Disease Control and Prevention (CDC). 19 December 2016. ... with manufacturing capacity being built up in the 2000s due to fears of bioterrorism and biological warfare. The first- ... the vaccine is still being produced to guard against bioterrorism, biological warfare, and monkeypox. The term vaccine derives ...
... bioterrorism; adulteration and quarantine matters; research, education, and extension; and biotechnology. Scott, Thompson ...
Bioterrorism". In Kenneth H. Mayer (ed.). The Social Ecology of Infectious Diseases. H.F. Pizer. London: Elsevier. p. 331. ISBN ... Bioterrorism in the context of infectious diseases". In Felissa R. Lashley (ed.). Emerging Infectious Diseases: Trends and ... In 2003, he received a Distinguished Service Award from the District of Columbia Hospital Association for Bioterrorism ... he has taught students on bioterrorism and emerging infectious disease. In 2014, he became a senior scholar with the O'Neill ...
Bioterrorism Week. NewsRX. 14 September 2009. ""Plaza Sésamo" educa sobre la gripe porcina". People en Español (in Spanish). ...
"First Nations and Native American Leaders Arrested In Front Of White House To Protest Keystone XL Pipeline". Bioterrorism Week ...
"Meta-Leadership and National Emergency Preparedness: A Model to Build Government Connectivity." Biosecurity & Bioterrorism. 4:2 ... "Meta-Leadership and National Emergency Preparedness: A Model to Build Government Connectivity." Biosecurity & Bioterrorism. 4:2 ... Bioterrorism. It was further developed through work with Dr. Isaac Ashkenazi and, later, Eric J. McNulty. The Meta-leadership ...
"Meta-Leadership and National Emergency Preparedness: A Model to Build Government Connectivity." Biosecurity & Bioterrorism. 4:2 ... Bioterrorism. 4:2, Summer 2006 Marcus, L.J., Ashkenazi, I, Dorn, B., & Henderson, J. "Meta-leadership: Expanding the Scope and ...
Microorganisms and Bioterrorism. New York City: Springer. p. 26. ISBN 9780387281568. Wilson, James M.; Brediger, Walter; ... "Historical Perspectives of Microbial Bioterrorism". In Anderson, Burt; Friedman, Herman; Bendinelli, Mauro (eds.). ...
Biosecurity and Bioterrorism. 10 (3): 290-298. doi:10.1089/bsp.2012.0011. ISSN 1538-7135. PMC 3440065. PMID 22871221. "The Deep ...
US Centers for Disease Control and Prevention (CDC). "Bioterrorism Agents/Diseases". Archived from the original on July 22, ... and by the Centers for Disease Control and Prevention as Category A Bioterrorism Agents, and are listed as Biological Agents ...
Hugh Pennington (5 September 2002). "Smallpox Scares: Bioterrorism". London Review of Books. 24 (17): 32-33. "Index entry". ...
"Bioterrorism Agents/Diseases". Centers for Disease Control and Prevention. Archived from the original on 2014-07-22.: ] " ... Bioterrorism and Infectious Agents: A New Dilemma for the 21st Century. Springer. pp. 99-145. ISBN 978-1-4419-1266-4. Whitlock ...
Pennington H (2003). "Smallpox and bioterrorism". Bull World Health Organ. 81 (10): 762-7. PMC 2572332. PMID 14758439. S2CID ...
Urbani Hiltebrand, E. & Armenti, C. (2003). Psychosocial Issues/Bioterrorism. (White paper). Los Angeles: The Annenberg Center ...
"Bioterrorism questions and answers". OREGON.gov. Archived from the original on May 27, 2010. Retrieved November 18, 2007. U.S. ... "Bioterrorism in History - 1984: Rajneesh Cult Attacks Local Salad Bar". NPR. Archived from the original on January 5, 2009. ... "Bioterrorism in Oregon". Emergency Film Group. Archived from the original on April 29, 2012. Retrieved November 18, 2007. ... Residents of The Dalles commented that they have an understanding of how bioterrorism can occur in the United States. The ...
"Syndromic Surveillance and Bioterrorism-related Epidemics". Medscape. Retrieved 12 August 2021. "Syndromic e-surveillance: ... Defence Against Bioterrorism. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer Netherlands: 123- ... "Rapid and Low-Cost Tools Derived from Plants to Face Emerging/Re-emerging Infectious Diseases and Bioterrorism Agents". ...
Bioterrorism Agents/Diseases. bt.cdc.gov Siva SR, Chong HT, Tan CT (2009). "Ten year clinical and serological outcomes of Nipah ...
Gronvall, G.K. (2012). Preparing for Bioterrorism: The Sloan Foundation's Leadership in Biosecurity. Center for Biosecurity of ... Biosecurity and Bioterrorism. 4 (1): 41-54. doi:10.1089/bsp.2006.4.41. PMID 16545023. Morse, S.S.; Garwin, R.L.; Olsiewski, P.J ...
Biosecurity and Bioterrorism. Carnegie Endowment for International Peace. 2 (1): 51-5. doi:10.1089/153871304322964345. PMID ...
Morse, Stephen A. (2006). "Historical Perspectives of Microbial Bioterrorism". In Anderson, Burt; Friedman, Herman; Bendinelli ... Mauro (eds.). Microorganisms and Bioterrorism. New York City: Springer. pp. 15-30. ISBN 9780387281568. O'Brien, Kevin ( ...
Encyclopedia of bioterrorism defense. Wiley-LISS, 2005. ISBN 0471467170. Polunin, Nicholas, Lynn M. Curme. World who is who and ...
Garrett, Laurie (January-February 2005). "The Nightmare of Bioterrorism". Foreign Affairs. Retrieved November 24, 2020. Garrett ...
ISBN 978-1-920942-62-5.{{cite book}}: CS1 maint: location (link) Pennington H (2003). "Smallpox and bioterrorism" (PDF). ...
"Virus: Bio-Terrorism Unlikely". CBS News. 11 February 2009. Retrieved 10 October 2013. v t e (Books with missing cover, 1999 ... Roos, Robert (19 September 2002). "CDC sees no evidence of bioterrorism in spread of West Nile virus". Center for Infectious ... Tucker, Jonathan B. "Improving Infectious Disease Surveillance to Combat Bioterrorism and Natural Emerging Infections". ...
Henderson, D. A. (2014). "John Bartlett and bioterrorism". Clinical Infectious Diseases. 59 (Supplement 2): S76-S79. doi: ... bioterrorism, and emerging and reemerging infectious agents, from anthrax to Zika. His wife, Joan née Scott, was a registered ... Bartlett was instrumental in educating the medical community and the general public about the dangers of bioterrorism. He and ...
ISBN 978-1-920942-62-5.{{cite book}}: CS1 maint: location (link) Pennington, Hugh (2003). "Smallpox and bioterrorism" (PDF). ...
2016, November 7). Bioterrorism Week, p. 23. Retrieved from http://link.galegroup.com/apps/doc/A468971075/PPWT?u=crepuq_bishop& ...
Encyclopedia of bioterrorism defense. Wiley-LISS, 2005. ISBN 0-471-46717-0. Thackrah, John Richard. Encyclopedia of Terrorism ...
The National Bioterrorism Syndromic Surveillance Demonstration Program identifies new cases of illness from electronic ... National Bioterrorism Syndromic Surveillance Demonstration Program. W. Katherine Yih,1 B. Caldwell,2 R. Harmon,3 K. Kleinman,1 ... The National Bioterrorism Syndromic Surveillance Demonstration Program covers a population of ,20 million persons, monitoring ... Martinez B. Questions of security: HealthPartners use reach, speedy data to hold watch for bioterrorism attacks. Wall Street ...
Learn how to prepare for a biological threat, as well as what to do during, and after a biological threat. Biological agents are organisms or toxins that can kill or disable people, livestock and crops. A biological attack is the deliberate release of germs or other biological substances that can make you sick. There are three basic groups of biological agents that could likely be used as weapons: bacteria, viruses and toxins. Biological agents can be spread by spraying them into the air, person-to-person contact, infecting animals that carry the disease to humans and by contaminating food and water.
Since September 11, 2001, federal, state, and local government agencies emergency response planning has focused on possible terrorist attacks using chemical, biological, radiological, nuclear, or high-yield explosive (CBRNE) weapons.
Endemic, Notifiable Bioterrorism-Related Diseases, United States, 1992-1999. Emerging Infectious Diseases 2003 May;9(5):556-564 ... Use of Automated Ambulatory-Care Encounter Records for Detection of Acute Illness Clusters, Including Potential Bioterrorism ...
2004)‎. Pakistans experience of a bioterrorism-related anthrax scare. EMHJ - Eastern Mediterranean Health Journal, 10 (‎1-2 ...
... Sunday, 01 February 2015 2:29 AM [ Last Update: Sunday, 01 February 2015 ... "the feasibility and potential impact of a non-state actor exploiting the Ebola outbreak in West Africa for bioterrorism," The ...
Bioterrorism. Defined by the Centers for Disease Control and Prevention: "A bioterrorism attack is the deliberate release of ... Bioterrorism Plans & Training. Plans and Protocols. 1. The City of Chesapeake writes and develops an Emergency Operations Plan ... Some bioterrorism agents, like the smallpox virus, can be spread from person to person and some, like anthrax, can not." ... The Food and Drug Administration - Drug Preparedness and Response to Bioterrorism (information on antibiotics and dosage) ...
... bioterrorism, and biological arms races with the public. ... bioterrorism, and biological arms races with the public. ...
2004)‎. Pakistans experience of a bioterrorism-related anthrax scare. EMHJ - Eastern Mediterranean Health Journal, 10 (‎1-2 ...
Endemic, Notifiable Bioterrorism-Related Diseases, United States, 1992-1999. Emerging Infectious Diseases 2003 May;9(5):556-564 ... Use of Automated Ambulatory-Care Encounter Records for Detection of Acute Illness Clusters, Including Potential Bioterrorism ...
Operations Research; Industrial Engineering; technical report; Markov process; inventory control; priority demand classes; service labels; backorder ...
BioterrorismDisease controlEmergency preparednessEmerging infectious diseasesEpidemicsHealth care facilitiesHealth hazards ... This testimony is based on Bioterrorism: Preparedness Varied across State and Local Jurisdictions, GAO-03-373 (Apr. 7, 2003); ... SARS Outbreak: Improvements to Public Health Capacity Are Needed for Responding to Bioterrorism and Emerging Infectious ... SARS Outbreak: Improvements to Public Health Capacity Are Needed for Responding to Bioterrorism and Emerging Infectious ...
Bioterrorism-related Anthrax Bioterrorism-related Anthrax. Molecular Subtyping of Bacillus anthracis and the 2001 Bioterrorism- ... Jernigan JA, Stephens DS, Ashford DA, Omenaca C, Topiel MS, Galbraith M, Bioterrorism-related inhalational anthrax: the first ... During the 2001 bioterrorism-associated anthrax outbreak, we used MLVA to subtype isolates from patients, the environment, and ... The recent bioterrorism-associated anthrax outbreak demonstrated the need for rapid molecular subtyping of Bacillus anthracis ...
Bacterial pathogens as biological weapons and agents of bioterrorism. Am J Med Sci. 2002;323:299-315. DOIPubMedGoogle Scholar ... Yagupsky P, Baron E. Laboratory Exposures to Brucellae and Implications for Bioterrorism. Emerging Infectious Diseases. 2005;11 ... by a laboratory may enable a bioterrorism-related attack to go undetected, whereas a false-positive identification may cause ... Yagupsky, P., & Baron, E. (2005). Laboratory Exposures to Brucellae and Implications for Bioterrorism. Emerging Infectious ...
... requires 24/7 coverage for the Health Alert Network as part of the bioterrorism grant program. ...
As veterinarians, we recognize that bioterrorism can also be aimed at animal populations (agri-bioterrorism), be they domestic ... The intentional dispersal of Bacillus anthracis spores in 2001 brought bioterrorism to the forefront of the American psyche and ... A wide variety of pathogens have been considered as potential agri-bioterrorism agents. The CIA has highlighted 15 animal ... After presenting the basic concepts of agri-bioterrorism, this seminar will review the clinical presentations in both domestic ...
Multiple Fatality Planning: Managing Mass Fatalities From a Variety of Causes, Including a Potential Bioterrorism Threat. ...
Ready or Not 2020: Protecting the Publics Health from Diseases, Disasters and Bioterrorism. Ready or Not provides an annual ... Ready or Not: Protecting the Publics Health from Diseases, Disasters and Bioterrorism is an annual report measuring states ... report - Mar 2021 Ready or Not 2021: Protecting the Publics Health From Diseases, Disasters, and Bioterrorism ... report - Feb 2019 Ready or Not: Protecting the Publics Health from Diseases, Disasters and Bioterrorism, 2019 ...
tags: Arestvyr, bioterrorism attack, politics, science, siga technologies, smallpox outbreak, smallpox vaccine, u s department ... Federal government purchases two million doses of smallpox drug in preparation for bioterrorism attack. March 19, 2013 ... "bioterrorism attack," according to The New York Times (NYT). ...
Review of Federal Bioterrorism Preparedness Programs From a Public Health Perspective: Hearing Before the Comm. on Commerce: U. ...
Title : Medical examiners, coroners, and bioterrorism. Personal Author(s) : Nolte, K. B.;Yoon, S. S.;Pertowski, C.; Published ...
Find the facts out about the vaccines that may be given in the event of a bioterrorism threat:*Anthrax vaccine ...
The Resource Bioterrorism -- Juvenile literature Label Bioterrorism -- Juvenile literature. Focus * Bioterrorism Sub Focus * ... Bioterrorism -- Juvenile literature Resource Information The concept Bioterrorism -- Juvenile literature represents the subject ... Data Citation of the Concept Bioterrorism -- Juvenile literature. Copy and paste the following RDF/HTML data fragment to cite ... Bioterrorism -- Juvenile literature,/a,,/span, - ,span property=potentialAction typeOf=OrganizeAction,,span property=agent ...
Ultra Compact Photonic Crystal Based Sensor for Detecting Bioterrorism. In: IEEE International Conference on Engineering and ... ring resonator structure which can sense anthrax in water in the wavelength range of 1530-1565 nm for detecting bioterrorism ...
Shahi SK, Ranga S, Gupta P. Bioterrorism. Indian Journal of Pathology & Microbiology. 2001 Oct; 44(4): 391-2. ...
Bioterrorism Bioterrorism is the use of bacteria, viruses, or germs to purposely harm large quantities of people or communities ...
Biodefense and Bioterrorism. * Anthrax: What You Need to Know - Amarɨñña / አማርኛ (Amharic) Bilingual PDF ...
Bioterrorism Terrorists could use coronavirus as example for future biological attack.. Introduction Well look at how this ... Intelligence, Biosecurity and Bioterrorism. This book explores how potential bio-threats and risks may evolve post 9/11 given ... Retired CIA officer Charles "Sam" Faddis, reminds us that the threat from bioterrorism is very real and not new. In fact, as he ... Biosecurity, bioterrorism and intelligence are all interconnected, the last one is the most important because a good ...
  • This testimony is based on Bioterrorism: Preparedness Varied across State and Local Jurisdictions, GAO-03-373 (Apr. (gao.gov)
  • Ready or Not: Protecting the Public's Health from Diseases, Disasters and Bioterrorism is an annual report measuring states' level of preparedness to protect the public's health during an emergency. (tfah.org)
  • Review of Federal Bioterrorism Preparedness Programs From a Public Health Perspective: Hearing Before the Comm. (dianepublishing.net)
  • States hold primary responsibility for organizing public health and bioterrorism preparedness activities. (essaylead.com)
  • Virologist C.J. Peters on bioterrorism preparedness. (technologyreview.com)
  • Bioterrorism preparedness. (technologyreview.com)
  • Cole's previous projects include research into bioterrorism preparedness, medical waste management in developing countries, and reduction of asthma and allergy triggers in indoor environments. (byu.edu)
  • To assess potential for early detection of oral infection by B. anthracis spores for preparedness of a bioterrorism attack. (bvsalud.org)
  • Some bioterrorism agents, like the smallpox virus, can be spread from person to person and some, like anthrax, can not. (virginia.gov)
  • Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United States. (cdc.gov)
  • Zaric GS , Bravata DM , Cleophas Holty JE , McDonald KM , Owens DK , Brandeau ML . Modeling the logistics of response to anthrax bioterrorism. (cdc.gov)
  • In this paper a photonic crystal based ring resonator structure which can sense anthrax in water in the wavelength range of 1530-1565 nm for detecting bioterrorism has been successfully demonstrated. (iisc.ac.in)
  • Anthrax is considered to be a bioterrorism threat mainly, because it can be created easily in a lab, and is very durable. (essaylead.com)
  • For these reasons, anthrax is considered a bioterrorism weapon. (essaylead.com)
  • More recently anthrax has been used in bioterrorism attacks in both Japan and the United States (Palemo, 2013). (essaylead.com)
  • In the fall of 2001, an outbreak of cutaneous and inhalation anthrax in New York City, New Jersey, the Washington, D.C. area and Florida resulted from a still unsolved act of bioterrorism involving letters intentionally contaminated with anthrax spores. (nyc.gov)
  • Bioterrorism has occurred in New York only in 2001, when media outlets received letters that were intentionally contaminated with anthrax bacteria. (nyc.gov)
  • The intentional dispersal of Bacillus anthracis spores in 2001 brought bioterrorism to the forefront of the American psyche and raised significant concerns among the general public for the risks of biologic attacks directed at our human population. (vin.com)
  • Following the terrorist attacks of September 11, 2001, the federal food safety agencies began taking on the added responsibility of addressing the potential for deliberate contamination of agriculture and food products - bioterrorism . (thoughtco.com)
  • 2021-04-21 It is aimed at intelligence analysts, those in the scientific community working on health security threats, policy makers and researchers working on biosecurity and bioterrorism threats and risks. (web.app)
  • Biosecurity, bioterrorism and intelligence are all interconnected, the last one is the most important because a good intelligence can reduce or even disrupt threats and emergencies by providing an It is aimed at intelligence analysts, those in the scientific community working on health security threats, policy makers and researchers working on biosecurity and bioterrorism threats and risks. (web.app)
  • extensive expertise in biosecurity, intelligence and bioterrorism issues made the work richer. (web.app)
  • Biosecurity, bioterrorism and intelligence are all interconnected, the last one is the most important because a good intelligence can reduce or even disrupt threats and emergencies by providing an extensive expertise in biosecurity, intelligence and bioterrorism issues made the work richer. (web.app)
  • I can only hope that the book serves to support the people I interviewed in some small way and those in our intelligence communi- It is aimed at intelligence analysts, those in the scientific community working on health security threats, policy makers and researchers working on biosecurity and bioterrorism threats and risks. (web.app)
  • Explore the ethical and policy concerns related to biosecurity Finally, we'll look at public health concerns related to biosecurity and bioterrorism events and evaluate the basic control measures for responding to such events. (web.app)
  • Intelligence Biosecurity and Bioterrorism Book Description : This book explores how potential bio-threats and risks may evolve post 9/11 given the rapid changes in biotechnology and synthetic biology. (web.app)
  • Retired CIA officer Charles "Sam" Faddis, reminds us that the threat from bioterrorism is very real and not new. (web.app)
  • This research explores policy responses to the threat from bioterrorism in the UK between 1990 and 2005. (sussex.ac.uk)
  • A wide variety of pathogens have been considered as potential agri-bioterrorism agents. (vin.com)
  • In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. (sbir.gov)
  • Now the occupying powers of the U.S. federal government are stockpiling millions of doses of smallpox medication in alleged preparation for a potential "bioterrorism attack," according to The New York Times (NYT). (wordpress.com)
  • https://www.cdc.gov/smallpox/bioterrorism-response-planning/public-health/enhanced-surveillance-case-reporting.html ) includes different criteria for a suspected case than the smallpox case definition the Council of State and Territorial Epidemiologists approved for use in the National Notifiable Diseases Surveillance System (NNDSS). (cdc.gov)
  • The smallpox case definition on the CDC bioterrorism web site is more sensitive and less specific than the case definition for the NNDSS, in that a "suspect" case is defined as: "a case with febrile rash illness with fever preceding the development of rash by 1-4 days. (cdc.gov)
  • http://www.wpro.who.int/emerging_diseases/documents/SecuringsRegHealth15/en/ [accessed 22 February 2018]. (who.int)
  • Global Health Security addresses the borderless dangers societies now face, including infectious diseases and bioterrorism, and examines the political, environmental, and socioeconomic factors exacerbating these threats. (amebaownd.com)
  • Health security expert Lawrence O. Gostin examines the key cross-border threats to our well-being, from infectious diseases to bioterrorism, and proposes Publisher: Harvard University PressPublication Date: September, 2021Assembled Product Dimensions (L x W x H): 9. (amebaownd.com)
  • Also known as biological warfare, bioterrorism is a form of warfare that uses specific microorganisms*, such as harmful bacteria and viruses, to cause illness or death deliberately in people or animals. (humanillnesses.com)
  • Bioterrorism involves terrorists or extremists, who apply microorganisms (bacteria, viruses, fungi) or toxins as weapons causing disease and/or death in humans, animals and/or plants [1-4]. (bvsalud.org)
  • COVID-19 injectable bioweapons as case study in legalized, government-operated domestic bioterrorism. (substack.com)
  • A few days ago, the President's Council of Advisors on Science and Technology (PCAST) wrote a letter to President Obama recommending the implementation of new countermeasures against bioterrorism threats. (wallstreetpit.com)
  • The extra funding would be intended to allow implementation of the Food Safety Modernization Act, which was signed into law on January 4, as well as boost bioterrorism countermeasures. (foodnavigator-usa.com)
  • With the spectre of bioterrorism looming larger, due to major disruptions caused by recent infectious disease outbreaks [1], we must make plans and develop strategies to prevent and respond to the deliberate spread of disease now. (woah.org)
  • Department of Health and Human Services Director Kathleen Sebelius in a statement called Hamburg "an inspiring public health leader with broad experience in infectious disease, bioterrorism, and health policy. (genomeweb.com)
  • Public reports suggest the U.S. healthcare system does not have enough capacity to isolate patients during a large airborne infectious disease epidemic or bioterrorism event. (cdc.gov)
  • The Bipartisan Commission on Biodefense met to discuss the expanding landscape of current and future biological threats, the roles and responsibilities of the federal government in assessing and preparing for various biological threats, and biological weapons, bioterrorism, and biological arms races with the public. (homelandsecuritynewswire.com)
  • Dr. Kahn's talk was focused on her new book entitled "Who's in Charge: Leadership During Epidemics, Bioterrorism Attacks, and other Public Health Crises. (theoldguardofprinceton.org)
  • http://www.wpro.who.int/health_research/documents/Health_in_Asia_and_the_Pacific/en/ [accessed 22 February 2018]. (who.int)
  • Defined by the Centers for Disease Control and Prevention: "A bioterrorism attack is the deliberate release of viruses, bacteria, or other germs (agents) used to cause illness or death in people, animals, or plants. (virginia.gov)
  • The Centers for Disease Control and Prevention (CDC) requires 24/7 coverage for the Health Alert Network as part of the bioterrorism grant program. (delaware.gov)
  • Bioterrorism Attacks 3 host, where they reactivate and multiply. (essaylead.com)
  • Bioterrorism Attacks 4 can be an informative way to teach and educate. (essaylead.com)
  • The public themselves must also be aware of these bioterrorism attacks not if they come, but when they come. (essaylead.com)
  • The information tracked through the Ohio Department of Health's data-gathering software, Surgenet, is for responding to crises, such as bioterrorism or a pandemic, and shouldn't be released because it could be used in the response to a future terrorism attack, the agency argued. (cleveland.com)
  • Bioterrorism : guidelines for medical and public health management / Donald A. Henderson, Thomas V. Inglesby, Tara O'Toole. (who.int)
  • s ability to respond to bioterrorism rest largely in states public health system. (essaylead.com)
  • In concluding remarks, Dr. Kahn noted that bioterrorism, while a public issue which has to be dealt with by state and local agencies, is also a national security issue which requires an effective role for the federal government. (theoldguardofprinceton.org)
  • Bioterrorism Terrorists could use coronavirus as example for future biological attack. (web.app)
  • Brucellae are class 3 organisms and potential agents of bioterrorism. (cdc.gov)
  • As is evident from this list, agri-bioterrorism can involve infectious agents that are specific for one animal species or for many species, agents associated with low to high case fatality rates, agents that require or do not require a vector for transmission, and agents that are or are not infectious for human beings as well as animals. (vin.com)
  • After presenting the basic concepts of agri-bioterrorism, this seminar will review the clinical presentations in both domestic and exotic animal species of several of these agents. (vin.com)
  • Bioterrorism agents can be separated into three categories, depending how easily they can be spread. (essaylead.com)
  • Bioterrorism is the intentional use of biological agents, or germs, to cause illness. (nyc.gov)
  • However, the study of immunity, particularly in the elderly, can no longer be limited to efficacy of vaccination, given the emergence of new viral strains of common viruses, such as avian influenza, and the threat of using viruses to which there are no current vaccines as agents of bioterrorism. (msu.edu)
  • Bioterrorism is the use of bacteria, viruses, or germs to purposely harm large quantities of people or communities. (familydoctor.org)
  • ERBC (2007) website states that: A bioterrorism attack is the deliberate release of viruses, bacteria, or other germs used to cause illness or death in people, animals, or plants (ERBC, 2007). (essaylead.com)
  • A bioterrorism incident may occur quietly with no explosion and no forewarning. (medscape.com)
  • The National Bioterrorism Syndromic Surveillance Demonstration Program identifies new cases of illness from electronic ambulatory patient records. (cdc.gov)
  • We simulated a bioterrorism-related out- mals and continued during the next 9 days with an epi- break in a U.S. community to examine (prospectively) the demiologic investigation and the identification by federal community's reaction to the crisis and assess the need for authorities of intentional release of RVFV. (cdc.gov)
  • Web visitors can access articles on emergency situations such as bioterrorism, natural disasters and disease outbreaks. (blogspot.com)
  • Since first realizing the implications of the many Congressional statutes and Health and Human Services regulations adopted to create and operate the bioterrorism program, mostly between 1997 and the present, I've been intermittently finding the specific citations for each statement while researching related issues. (substack.com)
  • President Trump's proposed budget would close a laboratory dedicated to countering bioterrorism and providing the science behind bioterrorism response and recovery. (rand.org)
  • US government encourages development of new drugs for ARS in response to increasing threat of bioterrorism. (enzychem.com)
  • Bioterrorism: Capacity building and training (accessed on 22 August 2020). (woah.org)
  • At the same time, Bioterrorism Security Assessment Alliance member, Chris Redfield arrives in China, itself under threat of a bioterrorist attack. (gamerguides.com)
  • These four groups knew that the outbreak was fic- for risk communication during bioterrorism-related out- breaks. (cdc.gov)
  • The study was conducted following a request by the government for guidance on "the feasibility and potential impact of a non-state actor exploiting the Ebola outbreak in West Africa for bioterrorism," The Mirror reported on Saturday. (presstv.ir)
  • Once EC-18 gets approval for ARS drug, there is also a potential that it will be awarded Priority Review Voucher (PRV) from FDA as a drug against bioterrorism. (enzychem.com)
  • As veterinarians, we recognize that bioterrorism can also be aimed at animal populations (agri-bioterrorism), be they domestic, free-ranging, or exotic. (vin.com)
  • Moreover, a number of events have influenced and shaped the threat narrative of bioterrorism. (sussex.ac.uk)
  • Dr. David Swerdlow] Being prepared for bioterrorism events is very important. (cdc.gov)
  • This is a reworking of information posted previously, including at the bottom of the American Domestic Bioterrorism Program post. (substack.com)
  • Organization as bioterrorism type A agent [5]. (bvsalud.org)
  • Colonel Jake McCrea's mission is to get Dr. Jessie Stevens and her bioterrorism team in the air. (audible.com)
  • So in the setting of a bioterrorism event, PEP could save many lives. (cdc.gov)
  • Coxiella burnetii is a category B bioterrorism agent because it is highly infectious, rather resistant to heat and drying, and can become airborne and inhaled by humans. (cdc.gov)
  • Others are specifically written into the laws, but I don't yet have the citations because I've prioritized my research time investigating other issues related to the bioterrorism program. (substack.com)
  • The religious cult made national news after engaging in immigration fraud, busing homeless people to their commune, and perpetrating the largest bioterrorism attack in US history in an attempt to overthrow local government leaders. (listverse.com)
  • A case study approach is used to examine the emergence and rise of the bioterrorism threat, and the institutional arrangement in place to confront that threat. (sussex.ac.uk)
  • The concept Bioterrorism -- Juvenile literature represents the subject, aboutness, idea or notion of resources found in Internet Archive - Open Library . (archive.org)
  • In conclusion, bioterrorism is a reality that we must be ready to free at any time. (essaylead.com)