Biosensing Techniques
Nanotechnology
Conductometry
Silicon
Lab-On-A-Chip Devices
Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.
Electrochemical Techniques
Gold
Surface Plasmon Resonance
A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Molecular Imprinting
Streptavidin
Metal Nanoparticles
Transistors, Electronic
Nanowires
Semiconductors
Micro-Electrical-Mechanical Systems
Microtechnology
Manufacturing technology for making microscopic devices in the micrometer range (typically 1-100 micrometers), such as integrated circuits or MEMS. The process usually involves replication and parallel fabrication of hundreds or millions of identical structures using various thin film deposition techniques and carried out in environmentally-controlled clean rooms.
Nanostructures
Microfluidics
Nanopores
Graphite
Optical Phenomena
Electrochemistry
Microfluidic Analytical Techniques
Quantum Dots
Optical Devices
Nanotubes
Equipment Failure Analysis
Limit of Detection
Electrodes
Surface Properties
Glucose Oxidase
An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.
Aptamers, Nucleotide
Quartz Crystal Microbalance Techniques
Interferometry
Enzymes, Immobilized
Ion-Selective Electrodes
Electronics
Avidin
Polymers
Nanoparticles
Electric Power Supplies
Biotin
Porosity
Spectrum Analysis, Raman
Nanotubes, Carbon
Photons
Silicon Dioxide
Oxides
Silver
Immunoassay
Membranes, Artificial
Adsorption
Antibodies
Microscopy, Electron, Scanning
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Direct interaction of lignin and lignin peroxidase from Phanerochaete chrysosporium. (1/3180)
Binding properties of lignin peroxidase (LiP) from the basidiomycete Phanerochaete chrysosporium against a synthetic lignin (dehydrogenated polymerizate, DHP) were studied with a resonant mirror biosensor. Among several ligninolytic enzymes, only LiP specifically binds to DHP. Kinetic analysis revealed that the binding was reversible, and that the dissociation equilibrium constant was 330 microM. The LiP-DHP interaction was controlled by the ionization group with a pKa of 5.3, strongly suggesting that a specific amino acid residue plays a role in lignin binding. A one-electron transfer from DHP to oxidized intermediates LiP compounds I and II (LiPI and LiPII) was characterized by using a stopped-flow technique, showing that binding interactions of DHP with LiPI and LiPII led to saturation kinetics. The dissociation equilibrium constants for LiPI-DHP and LiPII-DHP interactions were calculated to be 350 and 250 microM, and the first-order rate constants for electron transfer from DHP to LiPI and to LiPII were calculated to be 46 and 16 s-1, respectively. These kinetic and spectral studies strongly suggest that LiP is capable of oxidizing lignin directly at the protein surface by a long-range electron transfer process. A close look at the crystal structure suggested that LiP possesses His-239 as a possible lignin-binding site on the surface, which is linked to Asp-238. This Asp residue is hydrogen-bonded to the proximal His-176. This His-Asp...proximal-His motif would be a possible electron transfer route to oxidize polymeric lignin. (+info)Absorption of solar radiation by an ellipsoid sensor simulated the human body. (2/3180)
Assessment of heat gain in man caused by solar radiation is one of the most important problems in research of the human heat balance outdoors. The purpose of the present study was to investigate a new method for estimation of solar heat income. Absorption of short wave radiation (direct, diffuse and reflected) was measured with an ellipsoid sensor representing a simple, physical model of man. Measurements were performed in climatic chamber with the use of an iodide CSI solar lamp. The absorbed quantity of solar radiation varied as a result of sun altitude as well as of a colour and insulation of fabric covering the ellipsoid sensor. The new coefficients derived from our investigations for estimating doses of absorbed solar radiation should be applicable for a standing man. They correlate better with mean skin temperature observed on subjects outdoor than previous results obtained based on a cylinder as an analogue model of man. The ellipsoid sensor covered by a black fabric absorbed about 6 times more of solar radiation than when covered by a white textile. (+info)T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics. (3/3180)
The T cell surface glycoprotein CD8 enhances T cell antigen recognition by binding to MHC class I molecules. We show that human CD8 alphaalpha binds to the MHC class I molecule HLA-A2 with an extremely low affinity (Kd approximately 0.2 mM at 37 degrees C) and with kinetics that are between 2 and 3 orders of magnitude faster than reported for T cell receptor/peptide-MHC interactions. Furthermore, CD8 alphaalpha had no detectable effect on a T cell receptor (TCR) binding to the same peptide-MHC class I complex. These binding properties provide an explanation as to why the CD8/MHC class I interaction is unable to initiate cell-cell adhesion and how it can enhance TCR recognition without interfering with its specificity. (+info)Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. (4/3180)
The kinetics of interaction between TCR and MHC-peptide show a general relationship between affinity and the biological response, but the reported kinetic differences between antigenic and antagonistic peptides are very small. Here, we show a remarkable difference in the kinetics of TCR interactions with strong agonist ligands at 37 degrees C compared to 25 degrees C. This difference is not seen with antagonist/positive selecting ligands. The interaction at 37 degrees C shows biphasic binding kinetics best described by a model of TCR dimerization. The altered kinetics greatly increase the stability of complexes with agonist ligands, accounting for the large differences in biological response compared to other ligands. Thus, there may be an allosteric, as well as a kinetic, component to the discrimination between agonists and antagonists. (+info)Evaluation of relative contributions of two enzymes supposed to metabolise hydrogen peroxide in Paracoccus denitrificans. (5/3180)
A biosensor exploiting an electrochemically mediated enzyme-catalysed reaction was used to quantify relative contributions of cytoplasmic catalase and periplasmic cytochrome c peroxidase to the overall rate of hydrogen peroxide breakdown in cells of Paracoccus denitrificans. The effects of antimycin (an inhibitor of electron flow to cytochrome c peroxidase), the reaction rate versus substrate concentration profiles for the whole cells and subcellular fractions, and the time courses of oxygen concentration demonstrated a profound decrease in the capacity of cytochrome c peroxidase to reduce H2O2 under in vivo conditions. The reason is suggested to be a competition for available electrons between the enzyme and terminal oxidases metabolising oxygen produced by catalase. (+info)Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. (6/3180)
Lipoprotein lipase and the receptor-associated protein (RAP) bind to overlapping sites on the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor (LRP). We have investigated if lipoprotein lipase interacts with the RAP binding but structurally distinct receptor sortilin/neurotensin receptor-3. We show, by chemical cross-linking and surface plasmon resonance analysis, that soluble sortilin binds lipoprotein lipase with an affinity similar to that of LRP. The binding was inhibited by heparin and RAP and by the newly discovered sortilin ligand neurotensin. In 35S-labeled 3T3-L1 adipocytes treated with the cross-linker dithiobis(succinimidyl propionate), lipoprotein lipase-containing complexes were isolated by anti-sortilin antibodies. To elucidate function in cells, sortilin-negative Chinese hamster ovary cells were transfected with full-length sortilin and shown to express about 8% of the receptors on the cell surface. These cells degraded 125I-labeled lipoprotein lipase much faster than the wild-type cells. The degradation was inhibited by unlabeled lipoprotein lipase, indicating a saturable pathway, and by RAP and heparin. Moreover, inhibition by the weak base chloroquine suggested that degradation occurs in an acidic vesicle compartment. The results demonstrate that sortilin is a multifunctional receptor that binds lipoprotein lipase and, when expressed on the cell surface, mediates its endocytosis and degradation. (+info)Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. (7/3180)
Certain class II MHC-peptide complexes are resistant to SDS-induced dissociation. This property, which has been used as an in vivo as well as an in vitro peptide binding assay, is not understood at the molecular level. Here we have investigated the mechanistic basis of SDS stability of HLA-DR1 complexes by using a biosensor-based assay and SDS-PAGE with a combination of wild-type and mutant HLA-DR1 and variants of hemagglutinin peptide HA306-318. Experiments with wild-type DR1 along with previously published results establish that the SDS-stable complexes are formed only when the hydrophobic pocket 1 (P1) is occupied by a bulky aromatic (Trp, Phe, Tyr) or an aliphatic residue (Met, Ile, Val, Leu). To further explore whether the SDS sensitivity is primarily due to the exposed hydrophobic regions, we mutated residue beta Gly86 at the bottom of P1 to tyrosine, presumably reducing the depth of the pocket and the exposure of hydrophobic residues and increasing the contacts between subunits. In direct contrast to wild-type DR1, the peptide-free mutant DR1 exists as an alpha/beta heterodimer in SDS. Moreover, the presence of a smaller hydrophobic residue, such as alanine, as P1 anchor with no contribution from any other anchor is sufficient to enhance the SDS stability of the mutant complexes, demonstrating that the basis of SDS resistance may be localized to P1 interactions. The good correlation between SDS sensitivity and the exposure of hydrophobic residues provides a biochemical rationale for the use of this assay to investigate the maturation of class II molecules and the longevity of the complexes. (+info)Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin. (8/3180)
Domain IV of mouse perlecan, which consists of 14 immunoglobulin superfamily (IG) modules, was prepared from recombinant human cell culture medium in the form of two fragments, IV-1 (IG2-9, 100 kDa) and IV-2 (IG10-15, 66 kDa). Both fragments bound to a heparin column, being eluted at ionic strengths either below (IV-2) or above (IV-1) physiological level, and could thus be readily purified. Electron microscopy demonstrated an elongated shape (20-25 nm), and folding into a native structure was indicated by immunological assay and CD spectroscopy. Solid-phase and surface plasmon resonance assays demonstrated strong binding of fragment IV-1 to fibronectin, nidogen-1, nidogen-2 and the laminin-1-nidogen-1 complex, with Kd values in the range 4-17 nM. The latter binding apparently occurs through nidogen-1, as shown by the formation of ternary complexes. Only moderate binding was observed for fibulin-2 and collagen IV and none for fibulin-1 and BM-40. Fragment IV-2 showed a more restricted pattern of binding, with only weaker binding to fibronectin and fibulin-2. None of these activities could be demonstrated for recombinant fragments corresponding to the N-terminal perlecan domains I to III. This indicates a special role for domain IV in the integration of perlecan into basement membranes and other extracellular structures via protein-protein interactions. (+info)
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Novel biosensor of membrane protein proximity based on fluorogen activated proteins.
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Porous silicon
Pentane drying The technique uses pentane as the drying liquid instead of water. In doing so the capillary stress is reduced ... Ouyang, Huimin (2005). "Biosensing using porous silicon photonic bandgap structures". In Du, Henry H (ed.). Photonic Crystals ... and Ingeborg Uhlir at the Bell Labs in the U.S. At the time, the Ulhirs were in the process of developing a technique for ... Hence, several appropriate techniques have been developed to minimize the risk of cracks formed during drying. Supercritical ...
Droplet-based microfluidics
This technique is capable of running in excess of 2 million PCR reactions in addition to a 100,000-fold increase in the ... The above experiment by Shamsi et al, alludes to the main use for electrochemical detection in microfluidics; biosensing for ... Eventually a technique was developed to create monodisperse biodegradable microgels by making O/W emulsions in an in-line ... Another technique for creating particle-loaded microdroplets is the use of lipid-hydrogel nanoparticles that can be manipulated ...
Kinetic exclusion assay
An example of this technique has been employed for sensitive detection of environmental contaminants in near real-time. A ... Sensing and Bio-Sensing Research. 7: 115-120. doi:10.1016/j.sbsr.2016.02.003. PMC 4767017. PMID 26925369. (CS1 maint: multiple ...
Rolling circle replication
In addition to the amplification function in biosensing applications, RCA technique can be applied to the construction of DNA ... Selector-technique Ali, M. Monsur; Li, Feng; Zhang, Zhiqing; Zhang, Kaixiang; Kang, Dong-Ku; Ankrum, James A.; Le, X. Chris; ... This technique combines two fields: RCA, which allows nucleotide amplification, and immunoassay, which uses antibodies specific ... This amplification technique is named as Rolling circle amplification (RCA). Different from conventional DNA amplification ...
Mary Ryan (materials scientist)
She works with the heritage sector to develop new materials and conservation techniques. She has worked with the Science Museum ... including the toxicity of nanoparticles and development of plasmonic materials for biosensing. ... where she developed in situ electrochemical systems using synchrotron radiation-based techniques. Ryan is an expert in ...
Biomimetic material
Advanced manufacturing techniques like 3d printing are being used by the researcher to fabricate them. Materials Design ... Nanozymes as well as other artificial enzymes have found wide applications, from biosensing and immunoassays, to stem cell ...
Bio-MEMS
Optical detection includes fluorescence-based techniques, chemiluminescence-based techniques, and surface plasmon resonance ( ... The most common bioreceptors used in biosensing are based on antibody-antigen interactions, nucleic acid interactions, ... One common use for this technique is in detecting nucleotide mismatches in DNA because the variation in mass caused by the ... Conventional micromachining techniques such as wet etching, dry etching, deep reactive ion etching, sputtering, anodic bonding ...
Genetically modified organism
... a technique called phage display). These structures have potential uses for energy storage and generation, biosensing and ... A number of techniques are available for inserting the isolated gene into the host genome. Bacteria can be induced to take up ... A number of techniques are available for inserting the isolated gene into the host genome. Recent advancements using genome ... Gene targeting techniques, which creates double-stranded breaks and takes advantage on the cells natural homologous ...
Surface plasmon resonance
In general, SPR biosensing is demonstrating advantages over other approaches in the biomedical field due to this technique ... Related complementary techniques include plasmon waveguide resonance, QCM, extraordinary optical transmission, and dual- ... Due to the versatility of SPR instrumentation, this technique pairs well with other approaches, leading to novel applications ... Liedberg B, Nylander C, Lunström I (1983). "Surface plasmon resonance for gas detection and biosensing". Sensors and Actuators ...
Photonic crystal sensor
Cunningham, Brian T.; Zhang, Meng; Zhuo, Yue; Kwon, Lydia; Race, Caitlin (May 2016). "Recent Advances in Biosensing With ... "Simple and Precise Preparation of a Porous Gel for a Colorimetric Glucose Sensor by a Templating Technique". Angewandte Chemie ... Emiliyanov, Grigoriy; Høiby, Poul; Pedersen, Lars; Bang, Ole (2013-03-08). "Selective Serial Multi-Antibody Biosensing with ... biosensing, diagnostics, food quality control, security, and mechanical sensing.[citation needed] Many animals in nature such ...
Surface plasmon resonance microscopy
This technique is convenient to study the label free and real time interactions of cells on the surface. So SPRM can be served ... Anker, J, N; Hall, W, P; Lyandres, O; Shah, N, C; Zhao, J; Van Duyne, R, P (2008). "Biosensing with plasmonic nanosensors". ... In SPRM technique, plasmon surface polariton (PSP) waves are used for illumination. In simple words, SPRI technology is an ... As is seen in the image the remarkable contrast of the image is due to the high sensitivity of the technique.[citation needed] ...
Carbon nanotube supported catalyst
Inorganic compounds are directly formed on the surface of CNTs via a variety of techniques including electrochemical techniques ... Because of the excellent biological compatibility of Au, they are so frequently used in biosensing, medical and other related ... Hydrothermal techniques are developed in recent years. The advantage of this method is to get crystalline particles or films ... The characterization techniques of CNTs supported catalysts are varied. The most common methods include X-ray diffraction (XRD ...
Photonic metamaterial
A stacking technique for SRRs was published in 2007 that uses dielectric spacers to apply a planarization procedure to flatten ... Other potential applications include biosensing using nanoscale particles to deflect light to angles steep enough to travel ... Nanoscale fabrication techniques exist to accomplish subwavelength geometries. Metals such as gold, silver, aluminum and copper ... Fabrication techniques include electron beam lithography, nanostructuring with a focused ion beam and interference lithography ...
IRIS (biosensor)
By using interferometric techniques, nanometer changes can be detected. Applications for IRIS include microarray format ... is a system that can be used as a biosensing platform capable of high-throughput multiplexing of protein-protein, protein-DNA, ...
Grating-coupled interferometry
Forensic techniques, Protein-protein interaction assays, Plasmonics, Optical phenomena, All stub articles, Biophysics stubs). ... "Grating coupled optical waveguide interferometer for label-free biosensing". Sensors and Actuators B: Chemical (Band 155, Nr. 2 ...
Bio-layer interferometry
Syahir A, Usui K, Tomizaki KY, Kajikawa K, Mihara H (April 2015). "Label and Label-Free Detection Techniques for Protein ... Alongside Surface Plasmon Resonance, BLI is one of few widely available label-free biosensing technologies, a detection style ... Thus, BLI finds significant use in viscous media such as glycerol, where other techniques may struggle. Bio-layer ... Wilson JL, Scott IM, McMurry JL (November 2010). "Optical biosensing: Kinetics of protein A-IGG binding using biolayer ...
Single-walled carbon nanohorn
CO2 laser ablation technique is utilized to produce the first SWNHs at room temperature in absence of a metal catalyst. The CO2 ... Special designed SWNHs nanocomposites have versatile biosensing applications. One example is the sandwich nanohybrid of SWNHs- ... biosensing, drug delivery, gas storage and catalyst support for fuel cell. Single-walled carbon nanohorns are an example of the ... have been investigated by a combination of several techniques to show the electron-transfer process between the porphyrins and ...
Dawn Bonnell
The ability to visualize the atomic structure of surfaces and interfaces, and has applications in catalysis, biosensing and ... Techniques, and Applications. Wiley-Blackwell. ISBN 978-0471248248. Bonnell, Dawn (2013). Scanning Probe Microscopy For Energy ...
Surface plasmon polariton
The excitation of SPPs is frequently used in an experimental technique known as surface plasmon resonance (SPR). In SPR, the ... These devices include ultra-compact plasmonic interferometers for applications such as biosensing, optical positioning and ...
Biointerface
Being a FET device can also be taken advantage of when using single SiNWs as biosensing devices. SiNW sensors are nanowires ... scientists who have developed new spectroscopic techniques to interrogate these molecules at the solid-liquid interface, and ... and regenerative medicine Computational and modeling approaches to biointerfaces Membranes and membrane-based biosensing ...
Nanobiotechnology
The nanowires have a range of advantages over silicon nanowires and the memristors may be used to directly process biosensing ... Three American patients have received whole cultured bladders with the help of doctors who use nanobiology techniques in their ... Measurement in biology using wave guide techniques, such as dual-polarization interferometry, is another example. Applications ... biosensing, biological mechanisms such as mechanosensation), nanoscience of disease (e.g. genetic disease, cancer, organ/tissue ...
Biosensor
Many techniques exist to detect DNA, which is usually a means to detect organisms that have that particular DNA. DNA sequences ... The use of affinity binding receptors for purposes of biosensing has been proposed by Schultz and Sims in 1979 and was ... These techniques are mainly used in agriculture, food technology and biomedicine. In medical applications biosensors are ... improved the sensitivity of IRIS through a mass tagging technique. Since initial publication, IRIS has been adapted to perform ...
Stefan Seeger
He also developed techniques for the manipulation of biological particles. He has so far published more than 100 scientific ... Ruckstuhl, Thomas; Rankl, Michael; Seeger, Stefan (2003). "Highly sensitive biosensing using a supercritical angle fluorescence ...
Nanowire
The technique fuses wires as small as 10 nm. For nanowires with diameters less than 10 nm, existing welding techniques, which ... This method is investigated both for the synthesis of metallic nanowires in electronic components and for biosensing ... In one technique, the polyol synthesis, ethylene glycol is both solvent and reducing agent. This technique is particularly ... This technique allows to produce individual nanowires below 20 nm in width in a scalable way out of several metallic and metal ...
A. A. Griffith Medal and Prize
He is renowned for his understanding of the mechanics of materials, and for pioneering techniques that led to the study of ... Her nano-materials for biosensing have enabled the most sensitive facile enzyme detection to date and she is actively pursuing ...
Supercritical angle fluorescence microscopy
38 (4) 724-32 (1999) T. Ruckstuhl, M. Rankl, S. Seeger: Highly sensitive biosensing using a Supercritical Angle Fluorescence ( ... Supercritical angle fluorescence microscopy (SAF) is a technique to detect and characterize fluorescent species (proteins, ... v t e (Fluorescence techniques, Microscopy, Laser applications, All stub articles, Analytical chemistry stubs). ...
Förster resonance energy transfer
Fluorescence techniques, Cell biology, Laboratory techniques, Molecular biology techniques, Energy transfer). ... and biosensing. One common pair fluorophores for biological use is a cyan fluorescent protein (CFP) - yellow fluorescent ... FRET and FLIM Techniques. Laboratory Techniques in Biochemistry and Molecular Biology. Vol. 33. Elsevier. pp. 1-57. doi:10.1016 ... This technique can be used to determine factors affecting various types of nanoparticle formation as well as the mechanisms and ...
Printed electronics
This method uses techniques such as thermal, e-beam, sputter and other traditional production technologies to deposit materials ... 3.0.CO;2-E. Thomas, D.J. (2016). "Integration of Silicon and Printed Electronics for Rapid Diagnostic Disease Biosensing". ... This is an active research area, however, and print-compatible metal deposition techniques have been demonstrated that adapt to ... 2005). "Utilizing roll-to-roll techniques for manufacturing source-drain electrodes for all-polymer transistors". Synthetic ...
E-textiles
This in Finished approach entails the use of textile fabrication techniques to form woven or nonwoven fabrics with the ... These properties render them ideal substrates for electrochemical biosensing, which has been demonstrated with the detection of ... finished garments by simply stitching the electrodes at the appropriate locations on the garment or using deposition techniques ...
Reverse transcription polymerase chain reaction
This technique is easy to use since designing of probes is not necessary given lack of specificity of its binding. However, ... the one-step approach is a relatively convenient solution for the rapid detection of target RNA directly in biosensing.[ ... The combined RT-PCR and qPCR technique has been described as quantitative RT-PCR or real-time RT-PCR (sometimes even called ... The emergence of novel fluorescent DNA labeling techniques in the past few years has enabled the analysis and detection of PCR ...
Nanomaterial-based catalyst
Some techniques that can be used to characterize functionalized nanomaterial catalysts include X-ray photoelectron spectroscopy ... The nanozymes have found wide applications in many areas, from biosensing and bioimaging to therapeutics and water treatment. ...
Plasmonic metamaterial
More recently, researchers used a novel self-folding technique to create a three-dimensional array of split-ring resonators ... 2015). "Graphene-gold metasurface architectures for ultrasensitive plasmonic biosensing". Advanced Materials. 27 (40): 1-7. doi ... The material was created using epitaxy inside a vacuum chamber with a technique known as magnetron sputtering. The material ... Graphene also accommodates surface plasmons, observed via near field infrared optical microscopy techniques and infrared ...
Potential applications of graphene
In 2015 the technique was adapted to produce stacked, 3-D supercapacitors. Laser-induced graphene was produced on both sides of ... 2015). "Graphene-gold metasurface architectures for ultrasensitive plasmonic biosensing" (PDF). Advanced Materials. 27 (40): 1- ... Press Release (January 6, 2015). "'Flying Carpet' Technique Uses Graphene to Deliver One-Two Punch of Anticancer Drugs". North ... In February 2013 researchers announced a novel technique to produce graphene supercapacitors based on the DVD burner reduction ...
Transition metal dichalcogenide monolayers
This technique produces small samples of monolayer material, typically about 5-10 micrometers in diameter. Large quantities of ... Syu, Yu-Cheng; Hsu, Wei-En; Lin, Chih-Ting (2018-01-01). "Review-Field-Effect Transistor Biosensing: Devices and Clinical ... This technique is often used in the preparing electrical devices with molybdenum disulfide components because the nanosheets ... Electroplating Among the techniques that have been used to deposit molybdenum disulfide is electroplating. Ultra-thin films ...
Protein detection
C and the time is set to 15 minutes for the current abstraction technique. The current abstraction technique can restrain the ... Engineering the bioelectronic interface : applications to analyte biosensing and protein detection. Davis, Jason J., Royal ... Three different techniques can be used in raw ground beef: the VIDAS ultraperformance E. coli test (ECPT UP), a noncommercial ... These methods and techniques can be conveyed to lab environment easily. The original and traditional methods were designed and ...
Hatice Altug
Her research focuses on nanophotonics for biosensing and surface enhanced spectroscopy, integration with microfluidics and ... the development of innovative nanobiosensors and sensing techniques, and exemplary contributions to the scientific community ... for her groundbreaking achievements in confining and manipulating light at the nanoscale to dramatically improve biosensing ...
Stöber process
Applying supercritical drying techniques, a Stöber silica aerogel with a specific surface area of 700 m2 g−1 and a density of ... a convenient approach to preparing silica nanoparticles for applications including intracellular drug delivery and biosensing. ... Highly effective thermal insulators known as aerogels can also be prepared using Stöber methods, and Stöber techniques have ... In addition, experimental data from techniques including microgravity analysis and variable pH analysis agree with predictions ...
Slot-waveguide
2008-03-28). "Label-free optical biosensing with slot-waveguides". Optics Letters. The Optical Society. 33 (7): 708-10. doi: ... and nano-fabrication techniques. These processing tools include electron beam lithography, photolithography, chemical vapour ... or photo-lithography and dry etching techniques whereas in horizontal slot-waveguides the slot and strips thicknesses are ... defined by a thin-film deposition technique or thermal oxidation. Thin film deposition or oxidation provides better control of ...
Enzymatic biofuel cell
The beginning concept of applying enzymatic biofuel cells for self-powered biosensing applications has been introduced since ... The former technique is possible only with certain types of enzymes whose activation sites are close to the enzyme's surface, ... which meant that it was unusable until after immobilization techniques were devised. In addition, developers of enzymatic ...
I-motif DNA
Using a variety of biophysical techniques, i-motif DNA has been characterized to be derived from centromeres and promoter ... Applications of i-motifs are centered around biomedical topics, including bio-sensing, drug delivery systems, and molecular ...
Nanomaterials
Other techniques such direct probe method are used to determine the adhesive properties of nanomaterials. Both the technique ... They are an emerging type of artificial enzyme, which have been used for wide applications in such as biosensing, bioimaging, ... Techniques Used: Steinitz in 1943 used the micro-indentation technique to test the hardness of microparticles, and now ... "Refinement of the Nanoparticle Emission Assessment Technique into the Nanomaterial Exposure Assessment Technique (NEAT 2.0)". ...
Sangeeta N. Bhatia
She successfully applied techniques from photolithography to petri dishes, to create a substrate that would support growth of a ... July 15, 2006). Biosensing: International Research and Development. Springer Science & Business Media. ISBN 978-1-4020-4058-0. ... She and her coworkers have also used techniques from 3D printing to create a lattice of sugar as a framework for a synthetic ... July 15, 2006). Biosensing: International Research and Development. Springer Science & Business Media. ISBN 978-1-4020-4058-0. ...
Mehmet Toner
He has developed techniques in microtechnology and nanotechnology for use in clinical medicine, including the treatment of ... Toner's later work includes bio-sensing, regenerative medicine, and tissue engineering. He has helped to develop ...
Bioactive paper
Zhao, W.; Brook, M.A.; Li, Y.F. "Design of gold nanoparticle-based colorimetric biosensing assays." ChemBioChem, 2008, 9 (15), ... Kong, Fanzhi; Hu, Yim Fun (2012). "Biomolecule immobilization techniques for bioactive paper fabrication". Analytical and ...
Joseph Wang
... a novel motion-based DNA biosensing, nanomachine-enabled isolation of biological targets, such as cancer cell identification, ... Monitoring of Environmental Pollutants in Field Electrochemistry of Nucleic Acids and Proteins Electrochemical Techniques in ...
Ion track
This technique is applied to the counting and sizing of individual red blood cells, bacteria, and virus particles. pH Sensor: ... "Developing synthetic conical nanopores for biosensing applications". Molecular BioSystems. 3 (10): 667-685. doi:10.1039/ ... The technique can be used to increase the aspect ratio. Repeated irradiation and processing: A two-step irradiation and etching ... "Counting and sizing of submicron particles by the resistive pulse technique". Review of Scientific Instruments. 41 (7): 909-916 ...
Electromagnetic metasurface
Metasurface-empowered novel bioimaging and biosensing devices have also emerged and reported recently. For many optically based ... Luo, Xiangang; Ishihara, Teruya (2004). "Surface plasmon resonant interference nanolithography technique". Appl. Phys. Lett. 84 ... R. Ahmed (2020). "Tunable Fano‐resonant metasurfaces on a disposable plastic‐template for multimodal and multiplex biosensing ... 2015). "Graphene-gold metasurface architectures for ultrasensitive plasmonic biosensing". Advanced Materials. 27 (40): 6163- ...
Timeline of biotechnology
The nanowires have a range of advantages over silicon nanowires and the memristors may be used to directly process biosensing ... 1983 - The Polymerase Chain Reaction (PCR) technique is conceived. 1990 - First federally approved gene therapy treatment is ... 1877 - Robert Koch develops a technique for staining bacteria for identification. 1878 - Walther Flemming discovers chromatin ...
Localized surface plasmon
Some techniques frequently used to characterize surface plasmons are dark-field microscopy, UV-vis-NIR spectroscopy, and ... "Nanoparticle enhanced surface plasmon resonance biosensing: Application of gold nanorods". Optics Express. 17 (21): 19041-19046 ... Nanostructures exhibiting LSP resonances are used to enhance signals in modern analytical techniques based on spectroscopy. ...
Nanoprobes and nanobiosensors for monitoring and imaging individual living cells
Energy, Environment and Bio-sensing
| School of Computer Science and Electronic Engineering | Bangor University
Energy, Environment and Bio-sensing. Energy, Environment and Bio-sensing. Research in EEBG focuses on developing new low carbon ... Bangor University uses material analysis techniques to study causes of failure and use accelerated testing to predict stability ... Biosensing The school develops laboratory-on-chip technologies for diagnostics and biological cell treatment. Notably, our ... EEBG comprises of four laboratories and one institute: the solar, marine, biosensing, and environmental sensing laboratories, ...
Indian Institute of Technology Kharagpur
Whole cell biosensing via recA::mCherry and LED-based flow-through fluorometry<...
Biosensing Techniques Medicine & Life Sciences 56% * Mitomycin Medicine & Life Sciences 50% * Light Medicine & Life Sciences 48 ... Whole cell biosensing via recA::mCherry and LED-based flow-through fluorometry. / Martineau, R. L.; Stout, V.; Towe, B. C. ... Whole cell biosensing via recA::mCherry and LED-based flow-through fluorometry. Biosensors and Bioelectronics. 2009 Dec 15;25(4 ... Martineau, R. L. ; Stout, V. ; Towe, B. C. / Whole cell biosensing via recA::mCherry and LED-based flow-through fluorometry. In ...
Onur Dagliyan, Ph.D. | Harvard Catalyst Profiles | Harvard Catalyst
Biosensors | Free Full-Text | Magnetic Nanoparticle-Based Biosensing Assay Quantitatively Enhances Acid-Fast Bacilli Count in...
A new method using a magnetic nanoparticle-based colorimetric biosensing assay (NCBA) was compared with sputum smear microscopy ... Msm shares a similar cell wall structure with Mtb, both are AFB species, and both can be stained using the ZN technique [25,26 ... This technique could be easily integrated into conventional TB control programs in any resource-limited setting and where SSM ... Magnetic Nanoparticle-Based Biosensing Assay Quantitatively Enhances Acid-Fast Bacilli Count in Paucibacillary Pulmonary ...
Nanotweezers trap tiny objects
The technique allows objects to be picked up and moved to another place using just light. Although scientists have used optical ... One immediate application is in biosensing. "For example, nanotweezers can pick up a nanoparticle, deliver it to a desired ... "Measuring techniques like surface enhanced Raman measurements (SERS) could also be easily combined with nanotweezers." The team ... Said to offer many advantages over traditional optical tweezers, the new technique could open the way to manipulating fragile ...
LabRAM Soleil Nano - HORIBA
Surface-enhanced Raman scattering (SERS) is a powerful plasmonics-based analytical technique for biosensing. SERS effect relies ... Multi-technique / Multi-environment. Numerous SPM (scanning probe microscopy) modes including AFM, force curves measurements, ... Atomic Force Microscopy (AFM) associated to Raman spectroscopy has proven to be a powerful technique for probing chemical ... An information-rich, nanoscale characterization technique is required to qualify these materials and assist in the deployment ...
Dr Tianhua Xu | School of Engineering | University of Warwick
Z. Wang, T. Xu, A. Noel, Y. Chen, T. Liu, "Applications of liquid crystals in biosensingLink opens in a new window," [Royal ... Machine Learning Techniques in Optical Communication Systems. *Intelligent Signal Processing in Mitigating Optical Transmission ... Liquid Crystal Based Optical Biosensing Systems for Protein and DNA Detection. Topics for Research Visitors. *Optical ... Intelligent Signal Processing; Machine Learning Techniques. *Transceiver and Channel Modelling for Linear and Nonlinear Optical ...
Eval board for MEMS sensors features BLE connectivity
Design and simulation of a photonic crystal resonator as a biosensor for point-of-care applications
... resonator that would mitigate the drawbacks of the present sensing techniques. Photonic crystals consist of spatially arranged ... "THz biosensing devices: fundamentals and technology." Journal of Physics: Condensed Matter 18.18 (2006): S601.10.1088/0953-8984 ... resonator that would mitigate the drawbacks of the present sensing techniques. Photonic crystals consist of spatially arranged ... PC resonators have shown to have very high sensitivities for bio-sensing applications at THz frequencies. A PC resonator with a ...
QCM-D based biosensing - exploring the possibilities
The strength of the QCM-D technique, when compared to other biosensing techniques, is primarily its ability to sense ... One interesting technique in this context is quartz crystal microbalance with dissipation monitoring (QCM-D), biosensing ... To allow the monitoring of biomolecular interactions with a surface sensitive technique, such as QCM-D, surface modifications ... future work will be focused on finding biological systems where the QCM-D technique can provide new, unique biological ...
Course Catalogue - ETH Zurich
The most important biosensing techniques and their physical concepts are introduced in a quantitative fashion. ... learn the basic concepts in biosensing and bioelectronics. - be able to solve typical problems in biosensing and bioelectronics ... Fundamentals of biosensing. - Glucometer and ELISA L2. Fundamentals of quantum and classical noise in measuring biological ... Biomeasurement techniques with photons L4. Acoustics sensors - Differential equation for quartz crystal resonance. - Acoustic ...
Editors of 'Magnetic Nanoparticles in Biosensing and Medicine' Discuss the Field - Plus Free Chapter | FifteenEightyFour |...
Click here to check out a free chapter from Magnetic Nanoparticles in Biosensing and Medicine. The last decade has seen a ... to provide a crash course on magnetism and the concepts and equations governing magnetic materials and experimental techniques ... Click here to check out a free chapter from Magnetic Nanoparticles in Biosensing and Medicine. Full book available now at ... Editors of Magnetic Nanoparticles in Biosensing and Medicine Discuss the Field - Plus Free Chapter. Written by: Justin ...
Revzin, A.<...
British Library EThOS: Investigating type 2 diabetes related biosensing and amyloid peptide fibrillation
SHELLEY D MINTEER - Research - Faculty Profile - The University of Utah
S.D. Minteer, "Electroanalytical Techniques for Toxin Biosensing," Pittcon, Philadelphia, PA. Invited Talk/Keynote, Presented, ... S.D. Minteer & P. Baran (2020). Electrifying Synthesis: Recent Advances in the Methods, Materials, and Techniques for Organic ... The use of electroactive halophilia bacteria for improvements and advancements in environmental high saline biosensing. ...
Pittcon Conference + Expo From Bench to Bedside, The Biomedical Techniques Tackling Global Health Threats - Pittcon Conference ...
This article will cover recent advances in biomedical science and the ways these techniques could be applied to tackle current ... Nick Stone is Professor of Biomedical Imaging and Biosensing at the University of Exeter. On Tuesday, March 19th, he will give ... It is for this reason that Raman-based techniques that work in conjunction with other techniques have been developed. An ... From Bench to Bedside, The Biomedical Techniques Tackling Global Health Threats. March 14, 2019. Dr. Pete ConnContent, Life ...
IP Roundup: Omega Optics, OSU, Rosetta Genomics, Cancer Genetics, Nuclea Biomarkers, and Others | GenomeWeb
8,580,200, "Method for label-free multiple analyte sensing, biosensing and diagnostic assay." The patent claims an on-chip ... device that enables detection and identification of multiple species to be performed simultaneously using optical techniques ... leading to a high throughput device for chemical sensing, biosensing and medical diagnostics. According to the patent, the ...
Nanotechnology Spotlight Articles - Category All, page 16 | Nanowerk
Low-cost printing technique for a new generation of complex, flexible sensors. Printed electronics is one of the most important ... Perspectives for live cellular biosensing with nanowire arrays. In order to get a true picture of the processes and events that ... These techniques are inherently averaging and so are unable to effectively resolve mixtures of different-sized particles. While ... In new work, researchers have now expanded this technique to multiplexed assays. They demonstrated the ability to detect and ...
Surface Plasmon Polariton Graphene Photodetectors.
L-Serine Biosensor-Controlled Fermentative Production of L-Tryptophan Derivatives by Corynebacterium glutamicum - Fingerprint ...
Improving the biocatalyst. Engineering of fungal oxidoreductases and thin-film electrodes for improvement of membraneless...
Oxidative Stress and Mitochondrial Activation as the Main Mechanisms Underlying Graphene Toxicity against Human Cancer Cells
Graphene-based materials are promising in the field of biosensing and bioimaging (optical sensing, fluorescence imaging probes ... graphene nanomaterials have been used in advanced therapeutic techniques such as photothermal and photodynamic therapies [3, 16 ... used cell-based electrochemical impedance biosensing with interdigitated indium tin oxide (ITO) electrodes to analyze toxicity ... "Toxicity of graphene nanoflakes evaluated by cell-based electrochemical impedance biosensing," Journal of Biomedical Materials ...
MeSH Browser
Investigative Techniques [E05] * Molecular Probe Techniques [E05.601] * Biosensing Techniques [E05.601.043] * Surface Plasmon ... Investigative Techniques [E05] * Chemistry Techniques, Analytical [E05.196] * Activation Analysis [E05.196.039] * Analytic ... Biosensing Techniques (1991-1998). Public MeSH Note. 99. History Note. 99. Date Established. 1999/01/01. Date of Entry. 1998/06 ... A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one ...
Michal Lipson Elected to National Academy of Sciences | Electrical Engineering
Enzyme Biosensor for Detection of Organophosphate Pesticide Residues Base on |i|Screen Printed Carbon Electrode|/i| (SPCE)...
Artículos de revista DIEC - IEKS Aldizkari artikuluak
AC coupled amplifier with a resistance multiplier technique for ultra-low frequency operation Martincorena Arraiza, Maite ; ... Lossy mode resonance based microfluidic platform developed on planar waveguide for biosensing applications Benítez Pérez, ... In this article, a compact coplanar waveguide (CPW) technique based ultra-wideband multiple-input-multiple-output (MIMO) ... in recent years due to the excellent optical fiber properties and progress in the research on materials and techniques that ...
BiosensorsFluorescence imaginDiagnosticsMicrofluidicAssayElectrodeElectrochemicalApproachesMedicineAnalyticalTherapeutic techniquesChemicalMolecularOpticalOpticsMagneticDiagnosticResearchesBiomolecular interactionsWidelyLaboratoriesAnalyzeMeasurementsDetectionBiologicalBiomedicalQuartzApplicationsScientistsAdvancesResearch2019ConceptsVivoTemporalMethodReal-timePlaceAnalysisHighStudyPresent
Biosensors2
- This includes: spectroscopy-based techniques, lab-on-a-chip, mass spectrometry (including MALDI-TOF and proteomics), and the development of ultra-small biosensors. (pittcon.org)
- This chapter reviews the up-to-date researches in the field of biosensors integrated with microfluidic techniques, most of which are publications within the last 5 years. (intechopen.com)
Fluorescence imagin1
- Graphene-based materials are promising in the field of biosensing and bioimaging (optical sensing, fluorescence imaging probes, and electrochemical sensing) [ 4 , 5 , 12 , 18 ]. (hindawi.com)
Diagnostics3
- March 17 marks the start of Pittcon 2019, which will highlight a range of biomedical techniques that can provide improved diagnostics, better treatments and faster discovery. (pittcon.org)
- The patent claims an on-chip integrated microarray device that enables detection and identification of multiple species to be performed simultaneously using optical techniques leading to a high throughput device for chemical sensing, biosensing and medical diagnostics. (genomeweb.com)
- As it is a non-invasive, real-time technique it is an attractive imaging modality for medical applications such as cancer diagnostics, biosensing, and medical testing. (princetoninstruments.com)
Microfluidic1
- Here, we present a new capillary-based microfluidic biosensing approach to easily and reliably capture ~500 single cells inside isolated dead-end nanoliter compartments using simple pipette injection, and quantify their individual secretion dynamics at the single cell resolution over a long period of culture (~16 h). (garvan.org.au)
Assay1
- Despite recent efforts to capture cancer cells' intercellular secretion heterogeneity using microfluidics, the challenges in operation of these systems as well as the complexity of designing a biosensing assay for long-term and real-time measurement of single cell secretions have become grand research barriers. (garvan.org.au)
Electrode1
- Integrated Graphene, the Scottish technology integration company which has pioneered a high performing, low cost, 3D Graphene Foam electrode, Gii-Sens®, for biosensing, has partnered with a world-leading team of scientists to develop a point-of-care biomedical test to revolutionise the safety of liver transplants. (integratedgraphene.com)
Electrochemical1
- 3-D printed adjustable microelectrode arrays for electrochemical sensing and biosensing. (cdc.gov)
Approaches2
- The Feature Paper can be either an original research article, a substantial novel research study that often involves several techniques or approaches, or a comprehensive review paper with concise and precise updates on the latest progress in the field that systematically reviews the most exciting advances in scientific literature. (mdpi.com)
- In silico approaches are represented by techniques that use software to analyze data and often involve computational models or simulations based on existing information of closely related phenomena. (biomedscis.com)
Medicine2
- Click here to check out a free chapter from Magnetic Nanoparticles in Biosensing and Medicine . (cambridgeblog.org)
- The goal of this monograph is to provide a first point of reference for the design, synthesis and application of MNPs in biosensing and medicine, not only for newcomers, but also for established scientists looking for potentially new applications of their research. (cambridgeblog.org)
Analytical1
- Nanobiosensors and nanoprobes are a relatively new class of biosensing and imaging devices that allow for analytical measurements in individual living cells. (nih.gov)
Therapeutic techniques1
- Furthermore, graphene nanomaterials have been used in advanced therapeutic techniques such as photothermal and photodynamic therapies [ 3 , 16 ]. (hindawi.com)
Chemical1
- In this thesis, two T2D related pathogeneses, amyloidosis of T2D-related islet amyloid polypeptide (IAPP or amylin) and methylglyoxal (MGO, an α-dicarbonyl metabolite in T2D)-induced glycation were investigated by multiple techniques including chemical, structural, microscopic characterisations and computer simulations to probe the interactions at the bio-bio and bio-nano interfaces. (bl.uk)
Molecular2
- These results provided an attractive basis for the drug development industry to screen for interactions inducing multiple, reversible, conformational changes relying on molecular properties that cannot be easily detected by other techniques. (chalmers.se)
- Other in silico methods that are routinely used in research laboratories include molecular modelling (a technique used to model or mimic the structure of molecules) and protein sequencing and its alignment (methods used to evaluate identities and similarities in the amino acid sequence of proteins) [25-28]. (biomedscis.com)
Optical4
- Some of the recent sponsored projects undertaken by the department include development of silicon micro sensors using MEMS technology for MHRD, Govt of India, development of CORDIC chips and demonstration of its application in Doppler Ultra Sonography for DOE, Analysis Design and development of GTEM cell for ISRO Bangalore, Advanced Wavelength routed optical networks for European Union, Brussels, development of Video Codec using Wavelet Transform technique for Intel, USA. (iitkgp.ac.in)
- Said to offer many advantages over traditional optical tweezers, the new technique could open the way to manipulating fragile biological cells and making structures from nanoscale building blocks (Nature Photonics 2 365). (optics.org)
- His current research interests include optical communication systems and networks, intelligent signal processing, machine learning techniques, optical fibre sensing and opto-electronics. (warwick.ac.uk)
- Optical fluorescence imaging is one of the most common techniques for imaging in vivo, due to its high temporal and spatial resolution [1]. (princetoninstruments.com)
Optics1
- This architecture can also be used for surface plasmon biosensing with direct-electric-redout, eliminating the need of bulky optics. (cam.ac.uk)
Magnetic1
- Here, the aim is to provide a crash course on magnetism and the concepts and equations governing magnetic materials and experimental techniques. (cambridgeblog.org)
Diagnostic1
- The search is on for new antimicrobials and diagnostic techniques that can rapidly identify resistant organisms. (pittcon.org)
Researches1
- The 3D printed sensor was developed by the team of Rahul Panat, associate professor of Mechanical Engineering at Carnegie Mellon University, who researches additive manufacturing techniques for producing biosensing devices and human-computer interfaces. (drugdiscoverynews.com)
Biomolecular interactions2
- To allow the monitoring of biomolecular interactions with a surface sensitive technique, such as QCM-D, surface modifications are needed which allow the desired interactions to occur near the sensor surface while minimizing undesired effects. (chalmers.se)
- The technique is used to study biomolecular interactions, such as antigen-antibody binding. (nih.gov)
Widely2
- Near-infrared (NIR) fluorescence is a technique used widely within biological and medical research due to the fact that NIR light can penetrate deeply in biological specimens. (princetoninstruments.com)
- Fluorescence-based biosensing and bioimaging technologies are widely used in research and clinical settings to detect and image various biological species of interest. (wustl.edu)
Laboratories1
- EEBG comprises of four laboratories and one institute: the solar, marine, biosensing, and environmental sensing laboratories, and the nuclear futures institute. (bangor.ac.uk)
Analyze1
- Specializing in designing instruments to analyze pathogenic bacteria in air conditioning fluids, SPI Biosensing won second place and $5000, in the Technological and Technical Innovation category . (sherbrooke-innopole.com)
Measurements1
- Measuring techniques like surface enhanced Raman measurements (SERS) could also be easily combined with nanotweezers. (optics.org)
Detection4
- While fluorescence-based detection and imaging techniques are convenient to use, they suffer from poor sensitivity. (wustl.edu)
- The primary detection technique for SARS-CoV-2, the reverse-transcription polymerase chain reaction (RT-PCR)-based approach, requires expensive reagents and equipment and skilled personnel. (medscape.com)
- Recent advances in the field of CRISPR-based biosensing technologies for SARS-CoV-2 detection and insights into their potential use in many applications are reviewed in this article. (medscape.com)
- Researchers at the University of Bath working in collaboration with industrial partner, Integrated Graphene, have developed a new sensing technique based on graphene foam for the detection of glucose levels in the blood. (integratedgraphene.com)
Biological1
- Based on the procedures presented in this thesis, future work will be focused on finding biological systems where the QCM-D technique can provide new, unique biological information that has not been measured earlier with other methods. (chalmers.se)
Biomedical1
- This article will cover recent advances in clinical and biomedical science and the ways in which these techniques could be applied to tackle current global health threats. (pittcon.org)
Quartz1
- One interesting technique in this context is quartz crystal microbalance with dissipation monitoring (QCM-D), biosensing capabilities of which have been explored in this thesis. (chalmers.se)
Applications1
- As the team recently explained in the journal Light: Science and Applications , techniques to boost the signal - such as relying on enzyme-based amplification - require extra steps that prolong the overall operation time, as well as specialized and expensive read-out systems in some cases. (wustl.edu)
Scientists1
- Scientists rely on single-molecule techniques that allow them to isolate individual molecules and sequentially transport them for measurement and, potentially, manipulation. (nanowerk.com)
Advances2
- Technology is powering developments in biomedicine, with advances in computing power and imaging techniques providing just some of the solutions to today's biggest health issues. (pittcon.org)
- Her innovations involved techniques to tailor the electro-optic properties of silicon that led to the first major advances in silicon photonics, including demonstrating the ability to confine light well beyond the traditional diffraction limit using what she termed "slot waveguides. (columbia.edu)
Research1
- Current status of clinical research using artificial intelligence techniques: A registry-based audit. (cdc.gov)
20191
- At Pittcon 2019, Ester Segal will provide an overview of PRISM, a chip-based spectroscopic technique that can correctly guide a physician to the best antibiotic for an infection, reducing the misuse of these vital drugs. (pittcon.org)
Concepts2
Vivo1
- Such high throughput in vitro cell models of the epithelium could be used to predict the interaction of other nanoparticles with lung epithelial barriers to mimic respiratory behavior in vivo, thus providing essential tools and bio-sensing techniques that can be uniformly employed. (cdc.gov)
Temporal1
- The existing single molecule techniques are limited in their temporal resolution, probing the timescales on the order of several milliseconds to a second. (nanowerk.com)
Method1
- The method presented here overcomes the difficulties associated with performing single cell secretion assays, enabling a feasible and reliable technique for high throughput measurement of metabolic activities in cancer cells. (garvan.org.au)
Real-time1
- In order to get a true picture of the processes and events that take place inside unmodified, living cells, probing techniques need to be non-destructive, noninvasive and in real-time. (nanowerk.com)
Place2
- The technique allows objects to be picked up and moved to another place using just light. (optics.org)
- SPI Biosensing won two awards, and Rigolo, an amusement and development centre, won second place. (sherbrooke-innopole.com)
Analysis1
- Bangor University uses material analysis techniques to study causes of failure and use accelerated testing to predict stability in the future. (bangor.ac.uk)
High1
- The high degree of complexity of these systems can be investigated in greater and greater detail by increasingly sophisticated sensing techniques. (chalmers.se)
Study1
- The strength of the QCM-D technique, when compared to other biosensing techniques, is primarily its ability to sense viscoelastic, or nanomechanical, changes in the system under study. (chalmers.se)
Present1
- We aim to explain a bio-sensing concept using a photonic crystal (PC) resonator that would mitigate the drawbacks of the present sensing techniques. (degruyter.com)