Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.
Determination of the quantity of a material present in a mixture by measurement of its effect on the electrical conductivity of the mixture. (Webster, 3d ed)
A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].
Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.
The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.
A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
A methodology for chemically synthesizing polymer molds of specific molecules or recognition sites of specific molecules. Applications for molecularly imprinted polymers (MIPs) include separations, assays and biosensors, and catalysis.
A 60-kDa extracellular protein of Streptomyces avidinii with four high-affinity biotin binding sites. Unlike AVIDIN, streptavidin has a near neutral isoelectric point and is free of carbohydrate side chains.
Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.
Electrical devices that are composed of semiconductor material, with at least three connections to an external electronic circuit. They are used to amplify electrical signals, detect signals, or as switches.
Nanometer-scale wires made of materials that conduct electricity. They can be coated with molecules such as antibodies that will bind to proteins and other substances.
Materials that have a limited and usually variable electrical conductivity. They are particularly useful for the production of solid-state electronic devices.
A class of devices combining electrical and mechanical components that have at least one of the dimensions in the micrometer range (between 1 micron and 1 millimeter). They include sensors, actuators, microducts, and micropumps.
Manufacturing technology for making microscopic devices in the micrometer range (typically 1-100 micrometers), such as integrated circuits or MEMS. The process usually involves replication and parallel fabrication of hundreds or millions of identical structures using various thin film deposition techniques and carried out in environmentally-controlled clean rooms.
Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.
Methods of creating machines and devices.
The study of fluid channels and chambers of tiny dimensions of tens to hundreds of micrometers and volumes of nanoliters or picoliters. This is of interest in biological MICROCIRCULATION and used in MICROCHEMISTRY and INVESTIGATIVE TECHNIQUES.
Small holes of nanometer dimensions in a membrane, that can be used as single molecule detectors. The pores can be biological or synthetic.
An allotropic form of carbon that is used in pencils, as a lubricant, and in matches and explosives. It is obtained by mining and its dust can cause lung irritation.
LIGHT, it's processes and properties, and the characteristics of materials interacting with it.
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.
Coating with a metal or alloy by electrolysis.
Nanometer sized fragments of semiconductor crystalline material which emit PHOTONS. The wavelength is based on the quantum confinement size of the dot. They can be embedded in MICROBEADS for high throughput ANALYTICAL CHEMISTRY TECHNIQUES.
Products or parts of products used to detect, manipulate, or analyze light, such as LENSES, refractors, mirrors, filters, prisms, and OPTICAL FIBERS.
'Printing' in a medical context refers to the temporary or permanent transfer of ink from a substrate to the skin, often used for identification purposes, monitoring medical conditions, or as a form of temporary decoration.
Nanometer-sized tubes composed of various substances including carbon (CARBON NANOTUBES), boron nitride, or nickel vanadate.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
Characteristics or attributes of the outer boundaries of objects, including molecules.
An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
The use of a quartz crystal microbalance for measuring weights and forces in the micro- to nanogram range. It is used to study the chemical and mechanical properties of thin layers, such as polymer coatings and lipid membranes; and interactions between molecues.
Measurement of distances or movements by means of the phenomena caused by the interference of two rays of light (optical interferometry) or of sound (acoustic interferometry).
Enzymes which are immobilized on or in a variety of water-soluble or water-insoluble matrices with little or no loss of their catalytic activity. Since they can be reused continuously, immobilized enzymes have found wide application in the industrial, medical and research fields.
Electrodes which can be used to measure the concentration of particular ions in cells, tissues, or solutions.
The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A specific protein in egg albumin that interacts with BIOTIN to render it unavailable to mammals, thereby producing biotin deficiency.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
The physical effects involving the presence of electric charges at rest and in motion.
Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.
Devices that control the supply of electric current for running electrical equipment.
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.
Nanometer-sized tubes composed mainly of CARBON. Such nanotubes are used as probes for high-resolution structural and chemical imaging of biomolecules with ATOMIC FORCE MICROSCOPY.
Discrete concentrations of energy, apparently massless elementary particles, that move at the speed of light. They are the unit or quantum of electromagnetic radiation. Photons are emitted when electrons move from one energy state to another. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.
Binary compounds of oxygen containing the anion O(2-). The anion combines with metals to form alkaline oxides and non-metals to form acidic oxides.
Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
The study of MAGNETIC PHENOMENA.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.

Direct interaction of lignin and lignin peroxidase from Phanerochaete chrysosporium. (1/3180)

Binding properties of lignin peroxidase (LiP) from the basidiomycete Phanerochaete chrysosporium against a synthetic lignin (dehydrogenated polymerizate, DHP) were studied with a resonant mirror biosensor. Among several ligninolytic enzymes, only LiP specifically binds to DHP. Kinetic analysis revealed that the binding was reversible, and that the dissociation equilibrium constant was 330 microM. The LiP-DHP interaction was controlled by the ionization group with a pKa of 5.3, strongly suggesting that a specific amino acid residue plays a role in lignin binding. A one-electron transfer from DHP to oxidized intermediates LiP compounds I and II (LiPI and LiPII) was characterized by using a stopped-flow technique, showing that binding interactions of DHP with LiPI and LiPII led to saturation kinetics. The dissociation equilibrium constants for LiPI-DHP and LiPII-DHP interactions were calculated to be 350 and 250 microM, and the first-order rate constants for electron transfer from DHP to LiPI and to LiPII were calculated to be 46 and 16 s-1, respectively. These kinetic and spectral studies strongly suggest that LiP is capable of oxidizing lignin directly at the protein surface by a long-range electron transfer process. A close look at the crystal structure suggested that LiP possesses His-239 as a possible lignin-binding site on the surface, which is linked to Asp-238. This Asp residue is hydrogen-bonded to the proximal His-176. This His-Asp...proximal-His motif would be a possible electron transfer route to oxidize polymeric lignin.  (+info)

Absorption of solar radiation by an ellipsoid sensor simulated the human body. (2/3180)

Assessment of heat gain in man caused by solar radiation is one of the most important problems in research of the human heat balance outdoors. The purpose of the present study was to investigate a new method for estimation of solar heat income. Absorption of short wave radiation (direct, diffuse and reflected) was measured with an ellipsoid sensor representing a simple, physical model of man. Measurements were performed in climatic chamber with the use of an iodide CSI solar lamp. The absorbed quantity of solar radiation varied as a result of sun altitude as well as of a colour and insulation of fabric covering the ellipsoid sensor. The new coefficients derived from our investigations for estimating doses of absorbed solar radiation should be applicable for a standing man. They correlate better with mean skin temperature observed on subjects outdoor than previous results obtained based on a cylinder as an analogue model of man. The ellipsoid sensor covered by a black fabric absorbed about 6 times more of solar radiation than when covered by a white textile.  (+info)

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics. (3/3180)

The T cell surface glycoprotein CD8 enhances T cell antigen recognition by binding to MHC class I molecules. We show that human CD8 alphaalpha binds to the MHC class I molecule HLA-A2 with an extremely low affinity (Kd approximately 0.2 mM at 37 degrees C) and with kinetics that are between 2 and 3 orders of magnitude faster than reported for T cell receptor/peptide-MHC interactions. Furthermore, CD8 alphaalpha had no detectable effect on a T cell receptor (TCR) binding to the same peptide-MHC class I complex. These binding properties provide an explanation as to why the CD8/MHC class I interaction is unable to initiate cell-cell adhesion and how it can enhance TCR recognition without interfering with its specificity.  (+info)

Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. (4/3180)

The kinetics of interaction between TCR and MHC-peptide show a general relationship between affinity and the biological response, but the reported kinetic differences between antigenic and antagonistic peptides are very small. Here, we show a remarkable difference in the kinetics of TCR interactions with strong agonist ligands at 37 degrees C compared to 25 degrees C. This difference is not seen with antagonist/positive selecting ligands. The interaction at 37 degrees C shows biphasic binding kinetics best described by a model of TCR dimerization. The altered kinetics greatly increase the stability of complexes with agonist ligands, accounting for the large differences in biological response compared to other ligands. Thus, there may be an allosteric, as well as a kinetic, component to the discrimination between agonists and antagonists.  (+info)

Evaluation of relative contributions of two enzymes supposed to metabolise hydrogen peroxide in Paracoccus denitrificans. (5/3180)

A biosensor exploiting an electrochemically mediated enzyme-catalysed reaction was used to quantify relative contributions of cytoplasmic catalase and periplasmic cytochrome c peroxidase to the overall rate of hydrogen peroxide breakdown in cells of Paracoccus denitrificans. The effects of antimycin (an inhibitor of electron flow to cytochrome c peroxidase), the reaction rate versus substrate concentration profiles for the whole cells and subcellular fractions, and the time courses of oxygen concentration demonstrated a profound decrease in the capacity of cytochrome c peroxidase to reduce H2O2 under in vivo conditions. The reason is suggested to be a competition for available electrons between the enzyme and terminal oxidases metabolising oxygen produced by catalase.  (+info)

Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. (6/3180)

Lipoprotein lipase and the receptor-associated protein (RAP) bind to overlapping sites on the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor (LRP). We have investigated if lipoprotein lipase interacts with the RAP binding but structurally distinct receptor sortilin/neurotensin receptor-3. We show, by chemical cross-linking and surface plasmon resonance analysis, that soluble sortilin binds lipoprotein lipase with an affinity similar to that of LRP. The binding was inhibited by heparin and RAP and by the newly discovered sortilin ligand neurotensin. In 35S-labeled 3T3-L1 adipocytes treated with the cross-linker dithiobis(succinimidyl propionate), lipoprotein lipase-containing complexes were isolated by anti-sortilin antibodies. To elucidate function in cells, sortilin-negative Chinese hamster ovary cells were transfected with full-length sortilin and shown to express about 8% of the receptors on the cell surface. These cells degraded 125I-labeled lipoprotein lipase much faster than the wild-type cells. The degradation was inhibited by unlabeled lipoprotein lipase, indicating a saturable pathway, and by RAP and heparin. Moreover, inhibition by the weak base chloroquine suggested that degradation occurs in an acidic vesicle compartment. The results demonstrate that sortilin is a multifunctional receptor that binds lipoprotein lipase and, when expressed on the cell surface, mediates its endocytosis and degradation.  (+info)

Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. (7/3180)

Certain class II MHC-peptide complexes are resistant to SDS-induced dissociation. This property, which has been used as an in vivo as well as an in vitro peptide binding assay, is not understood at the molecular level. Here we have investigated the mechanistic basis of SDS stability of HLA-DR1 complexes by using a biosensor-based assay and SDS-PAGE with a combination of wild-type and mutant HLA-DR1 and variants of hemagglutinin peptide HA306-318. Experiments with wild-type DR1 along with previously published results establish that the SDS-stable complexes are formed only when the hydrophobic pocket 1 (P1) is occupied by a bulky aromatic (Trp, Phe, Tyr) or an aliphatic residue (Met, Ile, Val, Leu). To further explore whether the SDS sensitivity is primarily due to the exposed hydrophobic regions, we mutated residue beta Gly86 at the bottom of P1 to tyrosine, presumably reducing the depth of the pocket and the exposure of hydrophobic residues and increasing the contacts between subunits. In direct contrast to wild-type DR1, the peptide-free mutant DR1 exists as an alpha/beta heterodimer in SDS. Moreover, the presence of a smaller hydrophobic residue, such as alanine, as P1 anchor with no contribution from any other anchor is sufficient to enhance the SDS stability of the mutant complexes, demonstrating that the basis of SDS resistance may be localized to P1 interactions. The good correlation between SDS sensitivity and the exposure of hydrophobic residues provides a biochemical rationale for the use of this assay to investigate the maturation of class II molecules and the longevity of the complexes.  (+info)

Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin. (8/3180)

Domain IV of mouse perlecan, which consists of 14 immunoglobulin superfamily (IG) modules, was prepared from recombinant human cell culture medium in the form of two fragments, IV-1 (IG2-9, 100 kDa) and IV-2 (IG10-15, 66 kDa). Both fragments bound to a heparin column, being eluted at ionic strengths either below (IV-2) or above (IV-1) physiological level, and could thus be readily purified. Electron microscopy demonstrated an elongated shape (20-25 nm), and folding into a native structure was indicated by immunological assay and CD spectroscopy. Solid-phase and surface plasmon resonance assays demonstrated strong binding of fragment IV-1 to fibronectin, nidogen-1, nidogen-2 and the laminin-1-nidogen-1 complex, with Kd values in the range 4-17 nM. The latter binding apparently occurs through nidogen-1, as shown by the formation of ternary complexes. Only moderate binding was observed for fibulin-2 and collagen IV and none for fibulin-1 and BM-40. Fragment IV-2 showed a more restricted pattern of binding, with only weaker binding to fibronectin and fibulin-2. None of these activities could be demonstrated for recombinant fragments corresponding to the N-terminal perlecan domains I to III. This indicates a special role for domain IV in the integration of perlecan into basement membranes and other extracellular structures via protein-protein interactions.  (+info)

Biosensing techniques refer to the methods and technologies used to detect and measure biological molecules or processes, typically through the use of a physical device or sensor. These techniques often involve the conversion of a biological response into an electrical signal that can be measured and analyzed. Examples of biosensing techniques include electrochemical biosensors, optical biosensors, and piezoelectric biosensors.

Electrochemical biosensors measure the electrical current or potential generated by a biochemical reaction at an electrode surface. This type of biosensor typically consists of a biological recognition element, such as an enzyme or antibody, that is immobilized on the electrode surface and interacts with the target analyte to produce an electrical signal.

Optical biosensors measure changes in light intensity or wavelength that occur when a biochemical reaction takes place. This type of biosensor can be based on various optical principles, such as absorbance, fluorescence, or surface plasmon resonance (SPR).

Piezoelectric biosensors measure changes in mass or frequency that occur when a biomolecule binds to the surface of a piezoelectric crystal. This type of biosensor is based on the principle that piezoelectric materials generate an electrical charge when subjected to mechanical stress, and this charge can be used to detect changes in mass or frequency that are proportional to the amount of biomolecule bound to the surface.

Biosensing techniques have a wide range of applications in fields such as medicine, environmental monitoring, food safety, and biodefense. They can be used to detect and measure a variety of biological molecules, including proteins, nucleic acids, hormones, and small molecules, as well as to monitor biological processes such as cell growth or metabolism.

Nanotechnology is not a medical term per se, but it is a field of study with potential applications in medicine. According to the National Nanotechnology Initiative, nanotechnology is defined as "the understanding and control of matter at the nanoscale, at dimensions between approximately 1 and 100 nanometers, where unique phenomena enable novel applications."

In the context of medicine, nanotechnology has the potential to revolutionize the way we diagnose, treat, and prevent diseases. Nanomedicine involves the use of nanoscale materials, devices, or systems for medical applications. These can include drug delivery systems that target specific cells or tissues, diagnostic tools that detect biomarkers at the molecular level, and tissue engineering strategies that promote regeneration and repair.

While nanotechnology holds great promise for medicine, it is still a relatively new field with many challenges to overcome, including issues related to safety, regulation, and scalability.

Conductometry is a method used to measure the electrical conductivity of a solution, which can change in the presence of certain ions or chemical reactions. In conductometry, a conductivity probe or electrode is placed in the solution and an electrical current is passed through it. The resistance of the solution is then measured and converted into a measurement of conductivity.

Conductometry is often used to monitor chemical reactions that produce or consume ions, such as acid-base titrations, oxidation-reduction reactions, and complexation reactions. By measuring changes in conductivity over time, researchers can gain insights into the rate and extent of these reactions.

In medical research, conductometry may be used to study the electrical properties of biological tissues, such as skin or blood, or to monitor chemical processes in the body, such as the metabolism of drugs or other substances. However, it is not a commonly used diagnostic tool in clinical medicine.

I'm sorry for any confusion, but "Silicon" does not have a specific medical definition. Silicon is a chemical element with the symbol Si and atomic number 14. It is a metalloid, which means it has properties of both metals and nonmetals. In the human body, silicon is not considered an essential nutrient, although it is found in trace amounts in various tissues. Some research suggests that silicon might play a role in collagen synthesis and bone health, but more studies are needed to confirm these findings and establish recommended intake levels.

A Lab-on-a-Chip (LoC) device is a microfluidic system that integrates one or several laboratory functions on a single chip of only millimeters to a few square centimeters in size. These devices are designed to handle extremely small volumes of fluids, typically in the picoliter to microliter range, and perform various analytical operations such as sample preparation, separation, detection, and analysis.

LoC devices often incorporate different components like microchannels, reservoirs, pumps, valves, sensors, and biosensors to create a miniaturized laboratory environment. They offer numerous advantages over traditional laboratory methods, including faster analysis times, lower reagent consumption, reduced cost, higher throughput, enhanced portability, and improved automation.

LoC devices have found applications in various fields, such as clinical diagnostics, point-of-care testing, drug discovery and development, environmental monitoring, and basic research in areas like cell biology, proteomics, and genomics.

Electrochemical techniques are a group of analytical methods used in chemistry and biochemistry that involve the study of chemical processes that cause electrons to move. These techniques use an electrochemical cell, which consists of two electrodes (a working electrode and a counter electrode) immersed in an electrolyte solution. An electrical potential is applied between the electrodes, which drives redox reactions to occur at the electrode surfaces. The resulting current that flows through the cell can be measured and related to the concentration of analytes in the solution.

There are several types of electrochemical techniques, including:

1. Voltammetry: This technique measures the current that flows through the cell as a function of the applied potential. There are several types of voltammetry, including cyclic voltammetry, differential pulse voltammetry, and square wave voltammetry.
2. Amperometry: This technique measures the current that flows through the cell at a constant potential.
3. Potentiometry: This technique measures the potential difference between the working electrode and a reference electrode at zero current flow.
4. Impedance spectroscopy: This technique measures the impedance of the electrical circuit formed by the electrochemical cell as a function of frequency.

Electrochemical techniques are widely used in various fields, such as environmental monitoring, pharmaceuticals, food analysis, and biomedical research. They offer several advantages, including high sensitivity, selectivity, and simplicity, making them a powerful tool for chemical analysis.

I believe there may be some confusion in your question. Gold is typically a chemical element with the symbol Au and atomic number 79. It is a dense, soft, malleable, and ductile metal. It is one of the least reactive chemical elements and is solid under standard conditions.

However, if you are referring to "Gold" in the context of medical terminology, it may refer to:

1. Gold salts: These are a group of compounds that contain gold and are used in medicine for their anti-inflammatory properties. They have been used in the treatment of rheumatoid arthritis, although they have largely been replaced by newer drugs with fewer side effects.
2. Gold implants: In some cases, a small amount of gold may be surgically implanted into the eye to treat conditions such as age-related macular degeneration or diabetic retinopathy. The gold helps to hold the retina in place and can improve vision in some patients.
3. Gold thread embedment: This is an alternative therapy used in traditional Chinese medicine, where gold threads are embedded into the skin or acupuncture points for therapeutic purposes. However, there is limited scientific evidence to support its effectiveness.

I hope this information helps! If you have any further questions, please let me know.

Surface Plasmon Resonance (SPR) is a physical phenomenon that occurs at the interface between a metal and a dielectric material, when electromagnetic radiation (usually light) is shone on it. It involves the collective oscillation of free electrons in the metal, known as surface plasmons, which are excited by the incident light. The resonance condition is met when the momentum and energy of the photons match those of the surface plasmons, leading to a strong absorption of light and an evanescent wave that extends into the dielectric material.

In the context of medical diagnostics and research, SPR is often used as a sensitive and label-free detection technique for biomolecular interactions. By immobilizing one binding partner (e.g., a receptor or antibody) onto the metal surface and flowing the other partner (e.g., a ligand or antigen) over it, changes in the refractive index at the interface can be measured in real-time as the plasmons are disturbed by the presence of bound molecules. This allows for the quantification of binding affinities, kinetics, and specificity with high sensitivity and selectivity.

Molecular imprinting is a technique used in the production of polymer-based materials that have specific recognition sites for target molecules. It is a type of nanotechnology that involves creating a molecular template within a polymer matrix during its synthesis. The template is introduced into the polymer solution, and when the polymer hardens or sets, it takes on the shape and size of the template. After the template is removed, the resulting material has binding sites that are complementary in shape, size, and chemical functionality to the target molecule. These materials can then be used for various applications such as sensors, separations, drug delivery systems, and diagnostics.

Streptavidin is not a medical term per se, but rather a biochemical term used in the field of medicine and laboratory research. Streptavidin is a protein that is derived from the bacterium Streptomyces avidinii. It has a unique ability to bind very strongly and specifically to another molecule called biotin, with an association constant that is one of the strongest non-covalent interactions known in nature.

This property makes streptavidin a valuable tool in various medical and research applications such as immunoassays, histology, molecular biology, and drug delivery systems. For example, biotinylated molecules (such as antibodies, DNA, or enzymes) can be linked to streptavidin for detection, purification, or targeting purposes.

In summary, streptavidin is a bacterial protein that binds strongly and specifically to biotin, which is used in various medical and research applications as a tool for detection, purification, or targeting purposes.

Medical definitions generally refer to terms and concepts within the medical field. The term "metal nanoparticles" is more commonly used in materials science, chemistry, and physics. However, I can provide a general scientific definition that could be relevant to medical applications:

Metal nanoparticles are tiny particles with at least one dimension ranging from 1 to 100 nanometers (nm), composed of metals or metal compounds. They have unique optical, electronic, and chemical properties due to their small size and high surface-to-volume ratio, making them useful in various fields, including medical research. In medicine, metal nanoparticles can be used in drug delivery systems, diagnostics, and therapeutic applications such as photothermal therapy and radiation therapy. Examples of metals used for nanoparticle synthesis include gold, silver, and iron.

I'm sorry for any confusion, but "Transistors, Electronic" is not a recognized medical term. Transistors are electronic components used in various devices, including medical equipment, to amplify or switch electronic signals and electrical power. They are crucial for the functioning of numerous technologies, such as computers, smartphones, and other digital devices. However, they are not typically described in the context of medical definitions. If you have any questions related to electronics or technology that you believe could be relevant to a medical context, please provide more details so I can give a more accurate response.

I'm sorry for any confusion, but "nanowires" is not a medical term. It is a term used in the field of materials science and nanotechnology. Nanowires are one-dimensional structures with a diameter of 1-100 nanometers (nm) and an aspect ratio (length/diameter) greater than 1000. They have unique electrical, mechanical, and optical properties that make them useful in various applications such as electronics, sensors, energy storage, and biomedical devices.

I'm sorry for any confusion, but "semiconductors" is a term from the field of materials science and electronics rather than medicine. Semiconductors are materials, often silicon-based, that have properties between conductors and insulators. They are used in various electronic devices due to their unique property of controlling the flow of electrical current. If you have any medical questions, I'd be happy to help with those instead!

Micro-Electrical-Mechanical Systems (MEMS) is not a medical term, but rather a technology term that refers to the integration of mechanical elements, sensors, actuators, and electronic components on a single silicon chip through microfabrication technology. MEMS devices are extremely small (typically measured in micrometers or millionths of a meter), and can be found in various consumer products such as accelerometers in smartphones and automobiles, inkjet printheads, and biosensors.

In the medical field, MEMS technology has been used to develop various diagnostic and therapeutic devices, including lab-on-a-chip platforms for point-of-care diagnostics, drug delivery systems, and implantable sensors for monitoring physiological parameters such as glucose levels or blood pressure.

Therefore, while MEMS is not a medical definition itself, it is a technology that has significant applications in the medical field.

I'm sorry for any confusion, but "Microtechnology" is not a term that has a specific medical definition. Microtechnology generally refers to the development and application of technologies on a microscopic or tiny scale. It is used in various fields including engineering, physics, electronics, and materials science.

In the context of medicine, microtechnologies can be used in the development of medical devices, diagnostic tools, drug delivery systems, and other healthcare applications. For example, microfabrication techniques are used to create microfluidic devices for lab-on-a-chip applications, which can perform complex biochemical analyses for disease diagnosis or drug screening.

However, it's important to note that the application of microtechnologies in medicine is constantly evolving, and new developments and techniques are being explored all the time.

Nanostructures, in the context of medical and biomedical research, refer to materials or devices with structural features that have at least one dimension ranging between 1-100 nanometers (nm). At this size scale, the properties of these structures can differ significantly from bulk materials, exhibiting unique phenomena that are often influenced by quantum effects.

Nanostructures have attracted considerable interest in biomedicine due to their potential applications in various areas such as drug delivery, diagnostics, regenerative medicine, and tissue engineering. They can be fabricated from a wide range of materials including metals, polymers, ceramics, and carbon-based materials.

Some examples of nanostructures used in biomedicine include:

1. Nanoparticles: These are tiny particles with at least one dimension in the nanoscale range. They can be made from various materials like metals, polymers, or lipids and have applications in drug delivery, imaging, and diagnostics.
2. Quantum dots: These are semiconductor nanocrystals that exhibit unique optical properties due to quantum confinement effects. They are used as fluorescent labels for bioimaging and biosensing applications.
3. Carbon nanotubes: These are hollow, cylindrical structures made of carbon atoms arranged in a hexagonal lattice. They have exceptional mechanical strength, electrical conductivity, and thermal stability, making them suitable for various biomedical applications such as drug delivery, tissue engineering, and biosensors.
4. Nanofibers: These are elongated nanostructures with high aspect ratios (length much greater than width). They can be fabricated from various materials like polymers, ceramics, or composites and have applications in tissue engineering, wound healing, and drug delivery.
5. Dendrimers: These are highly branched, nanoscale polymers with a well-defined structure and narrow size distribution. They can be used as drug carriers, gene delivery vehicles, and diagnostic agents.
6. Nanoshells: These are hollow, spherical nanoparticles consisting of a dielectric core covered by a thin metallic shell. They exhibit unique optical properties that make them suitable for applications such as photothermal therapy, biosensing, and imaging.

Equipment design, in the medical context, refers to the process of creating and developing medical equipment and devices, such as surgical instruments, diagnostic machines, or assistive technologies. This process involves several stages, including:

1. Identifying user needs and requirements
2. Concept development and brainstorming
3. Prototyping and testing
4. Design for manufacturing and assembly
5. Safety and regulatory compliance
6. Verification and validation
7. Training and support

The goal of equipment design is to create safe, effective, and efficient medical devices that meet the needs of healthcare providers and patients while complying with relevant regulations and standards. The design process typically involves a multidisciplinary team of engineers, clinicians, designers, and researchers who work together to develop innovative solutions that improve patient care and outcomes.

Microfluidics is a multidisciplinary field that involves the study, manipulation, and control of fluids that are geometrically constrained to a small, typically sub-millimeter scale. It combines elements from physics, chemistry, biology, materials science, and engineering to design and fabricate microscale devices that can handle and analyze small volumes of fluids, often in the range of picoliters to microliters.

In medical contexts, microfluidics has numerous applications, including diagnostic testing, drug discovery, and personalized medicine. For example, microfluidic devices can be used to perform rapid and sensitive molecular assays for detecting pathogens or biomarkers in patient samples, as well as to screen drugs and evaluate their efficacy and toxicity in vitro.

Microfluidics also enables the development of organ-on-a-chip platforms that mimic the structure and function of human tissues and organs, allowing researchers to study disease mechanisms and test new therapies in a more physiologically relevant context than traditional cell culture models. Overall, microfluidics offers significant potential for improving healthcare outcomes by enabling faster, more accurate, and more cost-effective diagnostic and therapeutic strategies.

A nanopore is a tiny, narrow opening or passage at the molecular level, with a diameter typically measured in nanometers (nm). In the context of medicine and biology, nanopores are often used to describe protein structures that form water-filled channels across lipid membranes. These nanopores allow for the selective transport of ions, small molecules, or RNA/DNA strands between intracellular and extracellular spaces.

Nanopore technology has gained significant attention in medical research due to its potential applications in single-molecule analysis, diagnostics, and targeted drug delivery. For instance, nanopores can be used for rapid DNA sequencing by threading individual DNA strands through the pore and detecting changes in ionic current as nucleotides pass through. This information can then be translated into a sequence of bases, providing valuable insights into genetic makeup and potential disease markers.

I'm sorry for any confusion, but "graphite" is not a medical term. It is a mineral form of carbon that is used in various applications, such as pencils, lubricants, and batteries. If you have any medical questions or terms you would like defined, I'd be happy to help!

Optical phenomena refer to the various observable patterns and effects that occur due to the interaction of light with the environment or with structures in our eye. These can include natural phenomena such as rainbows, mirages, and halos around the sun or moon, as well as visual artifacts created by the eye itself, such as afterimages, floaters, and flashes of light. Some optical phenomena are caused by the refraction, reflection, or interference of light waves, while others may result from abnormalities in the eye's structure or function. Understanding these phenomena can provide insight into the properties of light and the functioning of the visual system.

Electrochemistry is a branch of chemistry that deals with the interconversion of electrical energy and chemical energy. It involves the study of chemical processes that cause electrons to move, resulting in the transfer of electrical charge, and the reverse processes by which electrical energy can be used to drive chemical reactions. This field encompasses various phenomena such as the generation of electricity from chemical sources (as in batteries), the electrolysis of substances, and corrosion. Electrochemical reactions are fundamental to many technologies, including energy storage and conversion, environmental protection, and medical diagnostics.

Microfluidic analytical techniques refer to the use of microfluidics, which is the manipulation of fluids in channels with dimensions of tens to hundreds of micrometers, for analytical measurements and applications. These techniques involve the integration of various functional components such as pumps, valves, mixers, and detectors onto a single chip or platform to perform chemical, biochemical, or biological analyses.

Microfluidic analytical techniques offer several advantages over traditional analytical methods, including reduced sample and reagent consumption, faster analysis times, increased sensitivity and throughput, and improved automation and portability. Examples of microfluidic analytical techniques include lab-on-a-chip devices, digital microfluidics, bead-based assays, and micro total analysis systems (μTAS). These techniques have found applications in various fields such as diagnostics, drug discovery, environmental monitoring, and food safety.

Electroplating is not a medical term, but rather a process used in the industrial field. It refers to the process of coating an electrically conductive object with a thin layer of metal through the use of an electrical current. This process involves immersing the object in a solution containing dissolved ions of the metal to be deposited, and then passing an electric current through the solution. The object serves as the cathode, and the metal ions are reduced at its surface, forming a thin layer of pure metal.

While electroplating is not directly related to medicine, it does have some medical applications. For example, medical devices such as pacemakers or implantable defibrillators may be coated with gold or other metals through electroplating to improve their biocompatibility and reduce the risk of corrosion or rejection by the body. Similarly, dental restorations may be electroplated with precious metals to enhance their strength and durability.

Quantum dots are not a medical term per se, but they are often referred to in the field of medical research and technology. Quantum dots are semiconductor nanocrystals that exhibit unique optical properties, making them useful for various applications in biology and medicine. They can range in size from 1 to 10 nanometers in diameter and can be composed of materials such as cadmium selenide (CdSe), indium arsenide (InAs), or lead sulfide (PbS).

In the medical context, quantum dots have been explored for use in bioimaging, biosensing, and drug delivery. Their small size and tunable optical properties make them ideal for tracking cells, proteins, and other biological molecules in real-time with high sensitivity and specificity. Additionally, quantum dots can be functionalized with various biomolecules, such as antibodies or peptides, to target specific cell types or disease markers.

However, it is important to note that the use of quantum dots in medical applications is still largely in the research stage, and there are concerns about their potential toxicity due to the heavy metals used in their composition. Therefore, further studies are needed to evaluate their safety and efficacy before they can be widely adopted in clinical settings.

An optical device is not a medical term per se, but rather a general term that describes any instrument or tool that uses light or electromagnetic radiation in the visible spectrum to observe, measure, or manipulate objects or phenomena. However, there are several optical devices that are commonly used in medical settings and have specific medical definitions. Here are some examples:

1. Ophthalmoscope: A handheld device used by healthcare professionals to examine the interior of the eye, including the retina, optic nerve, and vitreous humor. It typically consists of a handle, a light source, and a set of lenses that can be adjusted to focus on different parts of the eye.
2. Slit lamp: A specialized microscope used in ophthalmology to examine the structures of the eye at high magnification. It uses a narrow beam of light to illuminate the eye and allows the examiner to visualize details such as corneal abrasions, cataracts, and retinal lesions.
3. Microscope: A device that uses a system of lenses or mirrors to magnify objects or images, making them visible to the human eye. Microscopes are used in various medical fields, including pathology, hematology, and microbiology, to examine specimens such as tissues, cells, and microorganisms.
4. Endoscope: A flexible tube equipped with a light source and a camera that can be inserted into body cavities or passages to visualize internal structures. Endoscopes are used in procedures such as colonoscopy, gastroscopy, and laparoscopy to diagnose and treat conditions such as polyps, ulcers, and tumors.
5. Otoscope: A device used by healthcare professionals to examine the ear canal and eardrum. It typically consists of a handle, a light source, and a speculum that can be inserted into the ear canal to visualize the eardrum and identify any abnormalities such as inflammation, infection, or foreign bodies.
6. Refractor: A device used in optometry to measure the refractive error of the eye, or the amount of lens power needed to correct vision. The patient looks through a series of lenses while reading an eye chart, and the optometrist adjusts the lenses until the clearest vision is achieved.
7. Slit lamp: A microscope used in ophthalmology to examine the structures of the eye, including the cornea, iris, lens, and retina. The slit lamp uses a narrow beam of light to illuminate the eye and allow for detailed examination of any abnormalities or diseases.

I'm sorry for any confusion, but "printing" is not a term that has a specific medical definition. It generally refers to the process of producing text or images by impressing ink onto a surface, such as paper. If you have any questions related to healthcare or medical topics, I would be happy to try and help answer those for you!

Nanotubes, in the context of nanotechnology and materials science, refer to hollow cylindrical structures with extremely small diameters, measured in nanometers (nm). They are typically composed of carbon atoms arranged in a hexagonal lattice structure, similar to graphene. The most common types of nanotubes are single-walled nanotubes (SWNTs) and multi-walled nanotubes (MWNTs).

In the field of medicine, nanotubes have been studied for their potential applications in drug delivery, tissue engineering, and medical devices. For example, researchers have explored the use of nanotubes as drug carriers, where drugs can be loaded into the hollow interior of the tube and released in a controlled manner at the target site. Additionally, nanotubes have been used to create conductive scaffolds for tissue engineering, which may help promote nerve regeneration or muscle growth.

However, it's important to note that while nanotubes have shown promise in preclinical studies, their potential use in medical applications is still being researched and developed. There are concerns about the potential toxicity of nanotubes, as well as challenges related to their large-scale production and functionalization for specific medical applications.

Equipment Failure Analysis is a process of identifying the cause of failure in medical equipment or devices. This involves a systematic examination and evaluation of the equipment, its components, and operational history to determine why it failed. The analysis may include physical inspection, chemical testing, and review of maintenance records, as well as assessment of design, manufacturing, and usage factors that may have contributed to the failure.

The goal of Equipment Failure Analysis is to identify the root cause of the failure, so that corrective actions can be taken to prevent similar failures in the future. This is important in medical settings to ensure patient safety and maintain the reliability and effectiveness of medical equipment.

The 'Limit of Detection' (LOD) is a term used in laboratory medicine and clinical chemistry to describe the lowest concentration or quantity of an analyte (the substance being measured) that can be reliably distinguished from zero or blank value, with a specified level of confidence. It is typically expressed as a concentration or amount and represents the minimum amount of analyte that must be present in a sample for the assay to produce a response that is statistically different from a blank or zero calibrator.

The LOD is an important parameter in analytical method validation, as it helps to define the range of concentrations over which the assay can accurately and precisely measure the analyte. It is determined based on statistical analysis of the data generated during method development and validation, taking into account factors such as the variability of the assay and the signal-to-noise ratio.

It's important to note that LOD should not be confused with the 'Limit of Quantification' (LOQ), which is the lowest concentration or quantity of an analyte that can be measured with acceptable precision and accuracy. LOQ is typically higher than LOD, as it requires a greater level of confidence in the measurement.

An electrode is a medical device that can conduct electrical currents and is used to transmit or receive electrical signals, often in the context of medical procedures or treatments. In a medical setting, electrodes may be used for a variety of purposes, such as:

1. Recording electrical activity in the body: Electrodes can be attached to the skin or inserted into body tissues to measure electrical signals produced by the heart, brain, muscles, or nerves. This information can be used to diagnose medical conditions, monitor the effectiveness of treatments, or guide medical procedures.
2. Stimulating nerve or muscle activity: Electrodes can be used to deliver electrical impulses to nerves or muscles, which can help to restore function or alleviate symptoms in people with certain medical conditions. For example, electrodes may be used to stimulate the nerves that control bladder function in people with spinal cord injuries, or to stimulate muscles in people with muscle weakness or paralysis.
3. Administering treatments: Electrodes can also be used to deliver therapeutic treatments, such as transcranial magnetic stimulation (TMS) for depression or deep brain stimulation (DBS) for movement disorders like Parkinson's disease. In these procedures, electrodes are implanted in specific areas of the brain and connected to a device that generates electrical impulses, which can help to regulate abnormal brain activity and improve symptoms.

Overall, electrodes play an important role in many medical procedures and treatments, allowing healthcare professionals to diagnose and treat a wide range of conditions that affect the body's electrical systems.

Surface properties in the context of medical science refer to the characteristics and features of the outermost layer or surface of a biological material or structure, such as cells, tissues, organs, or medical devices. These properties can include physical attributes like roughness, smoothness, hydrophobicity or hydrophilicity, and electrical conductivity, as well as chemical properties like charge, reactivity, and composition.

In the field of biomaterials science, understanding surface properties is crucial for designing medical implants, devices, and drug delivery systems that can interact safely and effectively with biological tissues and fluids. Surface modifications, such as coatings or chemical treatments, can be used to alter surface properties and enhance biocompatibility, improve lubricity, reduce fouling, or promote specific cellular responses like adhesion, proliferation, or differentiation.

Similarly, in the field of cell biology, understanding surface properties is essential for studying cell-cell interactions, cell signaling, and cell behavior. Cells can sense and respond to changes in their environment, including variations in surface properties, which can influence cell shape, motility, and function. Therefore, characterizing and manipulating surface properties can provide valuable insights into the mechanisms of cellular processes and offer new strategies for developing therapies and treatments for various diseases.

Glucose oxidase (GOD) is an enzyme that catalyzes the oxidation of D-glucose to D-glucono-1,5-lactone, while reducing oxygen to hydrogen peroxide in the process. This reaction is a part of the metabolic pathway in some organisms that convert glucose into energy. The systematic name for this enzyme is D-glucose:oxygen 1-oxidoreductase.

Glucose oxidase is commonly found in certain fungi, such as Aspergillus niger, and it has various applications in industry, medicine, and research. For instance, it's used in the production of glucose sensors for monitoring blood sugar levels, in the detection and quantification of glucose in food and beverages, and in the development of biosensors for environmental monitoring.

It's worth noting that while glucose oxidase has many applications, it should not be confused with glutathione peroxidase, another enzyme involved in the reduction of hydrogen peroxide to water.

Aptamers are short, single-stranded oligonucleotides (DNA or RNA) that bind to specific target molecules with high affinity and specificity. They are generated through an iterative process called Systematic Evolution of Ligands by EXponential enrichment (SELEX), where large libraries of randomized oligonucleotides are subjected to repeated rounds of selection and amplification until sequences with the desired binding properties are identified. Nucleotide aptamers have potential applications in various fields, including diagnostics, therapeutics, and research tools.

The term "nucleotide" refers to the basic building blocks of nucleic acids (DNA and RNA). A nucleotide consists of a pentose sugar (ribose for RNA and deoxyribose for DNA), a phosphate group, and a nitrogenous base. The nitrogenous bases in nucleotides are adenine, guanine, cytosine, thymine (in DNA) or uracil (in RNA). In aptamers, the nucleotide sequences form specific three-dimensional structures that enable them to recognize and bind to their target molecules.

A Quartz Crystal Microbalance (QCM) is a type of physical analysis technique that uses the vibrations of a quartz crystal to measure changes in mass at a molecular or nanoscale level. When an alternating electrical field is applied to a quartz crystal, it causes the crystal to vibrate at a specific frequency. This phenomenon is known as the piezoelectric effect.

In QCM techniques, a thin film or material is deposited onto the surface of the quartz crystal, which changes its mass and therefore affects its vibrational frequency. By measuring the change in frequency before and after the deposition of the material, researchers can calculate the mass of the material that was added to the crystal's surface with high precision.

QCM techniques have a wide range of applications in research and industry, including the study of thin films, self-assembled monolayers, biosensors, and environmental monitoring. They are particularly useful for measuring changes in mass that occur on a very small scale, such as those associated with chemical reactions or biological interactions.

Interferometry is not specifically a medical term, but it is used in certain medical fields such as ophthalmology and optics research. Here is a general definition:

Interferometry is a physical method that uses the interference of waves to measure the differences in phase between two or more waves. In other words, it's a technique that combines two or more light waves to create an interference pattern, which can then be analyzed to extract information about the properties of the light waves, such as their wavelength, amplitude, and phase.

In ophthalmology, interferometry is used in devices like wavefront sensors to measure the aberrations in the eye's optical system. By analyzing the interference pattern created by the light passing through the eye, these devices can provide detailed information about the shape and curvature of the cornea and lens, helping doctors to diagnose and treat various vision disorders.

In optics research, interferometry is used to study the properties of light waves and materials that interact with them. By analyzing the interference patterns created by light passing through different materials or devices, researchers can gain insights into their optical properties, such as their refractive index, thickness, and surface roughness.

Immobilized enzymes refer to enzymes that have been restricted or fixed in a specific location and are unable to move freely. This is typically achieved through physical or chemical methods that attach the enzyme to a solid support or matrix. The immobilization of enzymes can provide several advantages, including increased stability, reusability, and ease of separation from the reaction mixture.

Immobilized enzymes are widely used in various industrial applications, such as biotransformations, biosensors, and diagnostic kits. They can also be used for the production of pharmaceuticals, food additives, and other fine chemicals. The immobilization techniques include adsorption, covalent binding, entrapment, and cross-linking.

Adsorption involves physically attaching the enzyme to a solid support through weak forces such as van der Waals interactions or hydrogen bonding. Covalent binding involves forming chemical bonds between the enzyme and the support matrix. Entrapment involves encapsulating the enzyme within a porous matrix, while cross-linking involves chemically linking multiple enzyme molecules together to form a stable structure.

Overall, immobilized enzymes offer several advantages over free enzymes, including improved stability, reusability, and ease of separation from the reaction mixture, making them valuable tools in various industrial applications.

Ion-Selective Electrodes (ISEs) are a type of chemical sensor that measure the activity of specific ions in a solution. They work by converting the chemical response into an electrical signal, which can then be measured and analyzed. The electrode is coated with a membrane that is selectively permeable to a particular ion, allowing for the detection and measurement of that specific ion in the presence of other ions.

ISEs are widely used in various fields such as clinical chemistry, biomedical research, environmental monitoring, and industrial process control. In medical diagnostics, ISEs are commonly used to measure the levels of ions such as sodium, potassium, chloride, and calcium in biological samples like blood, urine, and cerebrospinal fluid.

The response of an ISE is based on Nernst's equation, which relates the electrical potential across the membrane to the activity of the ion being measured. The selectivity of the electrode for a particular ion is determined by the type of membrane used, and the choice of membrane depends on the application and the specific ions to be measured.

Overall, Ion-Selective Electrodes are important tools in medical diagnostics and research, providing accurate and reliable measurements of ion activity in biological systems.

I believe there might be a misunderstanding in your question. "Electronics" is not a medical term, but rather a branch of physics and engineering that deals with the design, construction, and operation of electronic devices and systems. It involves the study and application of electrical properties of materials, components, and systems, and how they can be used to process, transmit, and store information and energy.

However, electronics have numerous applications in the medical field, such as in diagnostic equipment, monitoring devices, surgical tools, and prosthetics. In these contexts, "electronics" refers to the specific electronic components or systems that are used for medical purposes.

Avidin is a protein found in the white of eggs (egg whites) and some other animal tissues. It has a high binding affinity for biotin, also known as vitamin B7 or vitamin H, which is an essential nutrient for humans and other organisms. This property makes avidin useful in various biochemical and medical applications, such as immunohistochemistry, blotting techniques, and drug delivery systems.

Biotin-avidin interactions are among the strongest non-covalent interactions known in nature, with a dissociation constant (Kd) of approximately 10^-15 M. This means that once biotin is bound to avidin, it is very difficult to separate them. In some cases, this property can be exploited to create stable and specific complexes for various applications.

However, it's worth noting that the high affinity of avidin for biotin can also have negative effects in certain contexts. For example, raw egg whites contain large amounts of avidin, which can bind to biotin in the gut and prevent its absorption if consumed in sufficient quantities. This can lead to biotin deficiency, which can cause various health problems. Cooking egg whites denatures avidin and reduces its ability to bind to biotin, making cooked eggs a safe source of biotin.

In the context of medical definitions, polymers are large molecules composed of repeating subunits called monomers. These long chains of monomers can have various structures and properties, depending on the type of monomer units and how they are linked together. In medicine, polymers are used in a wide range of applications, including drug delivery systems, medical devices, and tissue engineering scaffolds. Some examples of polymers used in medicine include polyethylene, polypropylene, polystyrene, polyvinyl chloride (PVC), and biodegradable polymers such as polylactic acid (PLA) and polycaprolactone (PCL).

Electricity is not a medical term, but rather a fundamental aspect of physics and science. It refers to the form of energy resulting from the existence of charged particles such as electrons or protons, either statically as an accumulation of charge or dynamically as a current.

However, in the context of medical procedures and treatments, electricity is often used to stimulate nerves or muscles, destroy tissue through processes like electrocoagulation, or generate images of internal structures using methods like electrocardiography (ECG) or electroencephalography (EEG). In these cases, a clear medical definition would be:

The use of electric currents or fields in medical procedures for therapeutic or diagnostic purposes.

Nanoparticles are defined in the field of medicine as tiny particles that have at least one dimension between 1 to 100 nanometers (nm). They are increasingly being used in various medical applications such as drug delivery, diagnostics, and therapeutics. Due to their small size, nanoparticles can penetrate cells, tissues, and organs more efficiently than larger particles, making them ideal for targeted drug delivery and imaging.

Nanoparticles can be made from a variety of materials including metals, polymers, lipids, and dendrimers. The physical and chemical properties of nanoparticles, such as size, shape, charge, and surface chemistry, can greatly affect their behavior in biological systems and their potential medical applications.

It is important to note that the use of nanoparticles in medicine is still a relatively new field, and there are ongoing studies to better understand their safety and efficacy.

Electric power supplies are devices that convert electrical energy from a source into a form suitable for powering various types of equipment or devices. They can include a wide range of products such as batteries, generators, transformers, and rectifiers. The main function of an electric power supply is to maintain a stable voltage and current to the load, despite variations in the input voltage or changes in the load's electrical characteristics.

In medical terminology, electric power supplies are used in various medical devices such as diagnostic equipment, therapeutic machines, and monitoring systems. They provide a reliable source of power to these devices, ensuring their proper functioning and enabling accurate measurements and treatments. In some cases, medical power supplies may also include features such as uninterruptible power supply (UPS) systems or emergency power-off functions to ensure patient safety in the event of a power failure or other electrical issues.

Biotin is a water-soluble vitamin, also known as Vitamin B7 or Vitamin H. It is a cofactor for several enzymes involved in metabolism, particularly in the synthesis and breakdown of fatty acids, amino acids, and carbohydrates. Biotin plays a crucial role in maintaining healthy skin, hair, nails, nerves, and liver function. It is found in various foods such as nuts, seeds, whole grains, milk, and vegetables. Biotin deficiency is rare but can occur in people with malnutrition, alcoholism, pregnancy, or certain genetic disorders.

In the context of medical terminology, "porosity" is not a term that is frequently used to describe human tissues or organs. However, in dermatology and cosmetics, porosity refers to the ability of the skin to absorb and retain moisture or topical treatments.

A skin with high porosity has larger pores and can absorb more products, while a skin with low porosity has smaller pores and may have difficulty absorbing products. It is important to note that this definition of porosity is not a medical one but is instead used in the beauty industry.

Spectrum analysis in the context of Raman spectroscopy refers to the measurement and interpretation of the Raman scattering spectrum of a material or sample. Raman spectroscopy is a non-destructive analytical technique that uses the inelastic scattering of light to examine the vibrational modes of molecules.

When a monochromatic light source, typically a laser, illuminates a sample, a small fraction of the scattered light undergoes a shift in frequency due to interactions with the molecular vibrations of the sample. This shift in frequency is known as the Raman shift and is unique to each chemical bond or functional group within a molecule.

In a Raman spectrum, the intensity of the scattered light is plotted against the Raman shift, which is expressed in wavenumbers (cm-1). The resulting spectrum provides a "fingerprint" of the sample's molecular structure and composition, allowing for the identification and characterization of various chemical components within the sample.

Spectrum analysis in Raman spectroscopy can reveal valuable information about the sample's crystallinity, phase transitions, polymorphism, molecular orientation, and other properties. This technique is widely used across various fields, including materials science, chemistry, biology, pharmaceuticals, and forensics, to analyze a diverse range of samples, from simple liquids and solids to complex biological tissues and nanomaterials.

Carbon nanotubes (CNTs) are defined in medical literature as hollow, cylindrical structures composed of rolled graphene sheets, with diameters typically measuring on the nanoscale (ranging from 1 to several tens of nanometers) and lengths that can reach several micrometers. They can be single-walled (SWCNTs), consisting of a single layer of graphene, or multi-walled (MWCNTs), composed of multiple concentric layers of graphene.

Carbon nanotubes have unique mechanical, electrical, and thermal properties that make them promising for various biomedical applications, such as drug delivery systems, biosensors, and tissue engineering scaffolds. However, their potential toxicity and long-term effects on human health are still under investigation, particularly concerning their ability to induce oxidative stress, inflammation, and genotoxicity in certain experimental settings.

A photon is not a term that has a specific medical definition, as it is a fundamental concept in physics. Photons are elementary particles that carry electromagnetic energy, such as light. They have no mass or electric charge and exhibit both particle-like and wave-like properties. In the context of medicine, photons are often discussed in relation to various medical imaging techniques (e.g., X-ray imaging, CT scans, and PET scans) and therapeutic interventions like laser therapy and radiation therapy, where photons are used to diagnose or treat medical conditions.

Silicon dioxide is not a medical term, but a chemical compound with the formula SiO2. It's commonly known as quartz or sand and is not something that would typically have a medical definition. However, in some cases, silicon dioxide can be used in pharmaceutical preparations as an excipient (an inactive substance that serves as a vehicle or medium for a drug) or as a food additive, often as an anti-caking agent.

In these contexts, it's important to note that silicon dioxide is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA). However, exposure to very high levels of respirable silica dust, such as in certain industrial settings, can increase the risk of lung disease, including silicosis.

I'm sorry for any confusion, but "oxides" is not a term that has a specific medical definition. Oxides are a class of chemical compounds that contain at least one oxygen atom and one other element. They can be formed through the process of oxidation, which involves the combination of oxygen with another substance.

In a broader sense, you might encounter the term "oxide" in a medical context when discussing various materials or substances used in medical devices, treatments, or research. For instance, titanium dioxide is a common ingredient in medical-grade sunscreens due to its ability to block and scatter UV light. However, it's important to note that the term "oxides" itself doesn't have a direct connection to medicine or human health.

I'm sorry for any confusion, but "Silver" is not a medical term. It is a chemical element with the symbol Ag and atomic number 47. Silver is a soft, white, lustrous transition metal that occurs in its pure, free form (native silver) as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite.

In the medical field, silver compounds have been used for their antimicrobial properties. For example, silver sulfadiazine is a common topical cream used to prevent or treat wound infections. Colloidal silver, a suspension of silver particles in a liquid, has also been promoted as a dietary supplement and alternative treatment for various conditions, but its effectiveness and safety are not well-established.

An immunoassay is a biochemical test that measures the presence or concentration of a specific protein, antibody, or antigen in a sample using the principles of antibody-antigen reactions. It is commonly used in clinical laboratories to diagnose and monitor various medical conditions such as infections, hormonal disorders, allergies, and cancer.

Immunoassays typically involve the use of labeled reagents, such as enzymes, radioisotopes, or fluorescent dyes, that bind specifically to the target molecule. The amount of label detected is proportional to the concentration of the target molecule in the sample, allowing for quantitative analysis.

There are several types of immunoassays, including enzyme-linked immunosorbent assay (ELISA), radioimmunoassay (RIA), fluorescence immunoassay (FIA), and chemiluminescent immunoassay (CLIA). Each type has its own advantages and limitations, depending on the sensitivity, specificity, and throughput required for a particular application.

I'm sorry for any confusion, but "magnetics" is not a term that is commonly used in medical definitions. It is a term more frequently used in physics and engineering to refer to things related to magnets or magnetic fields. If you have any questions about medical terminology or concepts, I would be happy to try to help with those!

Artificial membranes are synthetic or man-made materials that possess properties similar to natural biological membranes, such as selective permeability and barrier functions. These membranes can be designed to control the movement of molecules, ions, or cells across them, making them useful in various medical and biotechnological applications.

Examples of artificial membranes include:

1. Dialysis membranes: Used in hemodialysis for patients with renal failure, these semi-permeable membranes filter waste products and excess fluids from the blood while retaining essential proteins and cells.
2. Hemofiltration membranes: Utilized in extracorporeal circuits to remove larger molecules, such as cytokines or inflammatory mediators, from the blood during critical illnesses or sepsis.
3. Drug delivery systems: Artificial membranes can be used to encapsulate drugs, allowing for controlled release and targeted drug delivery in specific tissues or cells.
4. Tissue engineering: Synthetic membranes serve as scaffolds for cell growth and tissue regeneration, guiding the formation of new functional tissues.
5. Biosensors: Artificial membranes can be integrated into biosensing devices to selectively detect and quantify biomolecules, such as proteins or nucleic acids, in diagnostic applications.
6. Microfluidics: Artificial membranes are used in microfluidic systems for lab-on-a-chip applications, enabling the manipulation and analysis of small volumes of fluids for various medical and biological purposes.

Adsorption is a process in which atoms, ions, or molecules from a gas, liquid, or dissolved solid accumulate on the surface of a material. This occurs because the particles in the adsorbate (the substance being adsorbed) have forces that attract them to the surface of the adsorbent (the material that the adsorbate is adhering to).

In medical terms, adsorption can refer to the use of materials with adsorptive properties to remove harmful substances from the body. For example, activated charcoal is sometimes used in the treatment of poisoning because it can adsorb a variety of toxic substances and prevent them from being absorbed into the bloodstream.

It's important to note that adsorption is different from absorption, which refers to the process by which a substance is taken up and distributed throughout a material or tissue.

Antibodies are proteins produced by the immune system in response to the presence of a foreign substance, such as a bacterium or virus. They are capable of identifying and binding to specific antigens (foreign substances) on the surface of these invaders, marking them for destruction by other immune cells. Antibodies are also known as immunoglobulins and come in several different types, including IgA, IgD, IgE, IgG, and IgM, each with a unique function in the immune response. They are composed of four polypeptide chains, two heavy chains and two light chains, that are held together by disulfide bonds. The variable regions of the heavy and light chains form the antigen-binding site, which is specific to a particular antigen.

Scanning electron microscopy (SEM) is a type of electron microscopy that uses a focused beam of electrons to scan the surface of a sample and produce a high-resolution image. In SEM, a beam of electrons is scanned across the surface of a specimen, and secondary electrons are emitted from the sample due to interactions between the electrons and the atoms in the sample. These secondary electrons are then detected by a detector and used to create an image of the sample's surface topography. SEM can provide detailed images of the surface of a wide range of materials, including metals, polymers, ceramics, and biological samples. It is commonly used in materials science, biology, and electronics for the examination and analysis of surfaces at the micro- and nanoscale.

Pentane drying The technique uses pentane as the drying liquid instead of water. In doing so the capillary stress is reduced ... Ouyang, Huimin (2005). "Biosensing using porous silicon photonic bandgap structures". In Du, Henry H (ed.). Photonic Crystals ... and Ingeborg Uhlir at the Bell Labs in the U.S. At the time, the Ulhirs were in the process of developing a technique for ... Hence, several appropriate techniques have been developed to minimize the risk of cracks formed during drying. Supercritical ...
This technique is capable of running in excess of 2 million PCR reactions in addition to a 100,000-fold increase in the ... The above experiment by Shamsi et al, alludes to the main use for electrochemical detection in microfluidics; biosensing for ... Eventually a technique was developed to create monodisperse biodegradable microgels by making O/W emulsions in an in-line ... Another technique for creating particle-loaded microdroplets is the use of lipid-hydrogel nanoparticles that can be manipulated ...
An example of this technique has been employed for sensitive detection of environmental contaminants in near real-time. A ... Sensing and Bio-Sensing Research. 7: 115-120. doi:10.1016/j.sbsr.2016.02.003. PMC 4767017. PMID 26925369. (CS1 maint: multiple ...
In addition to the amplification function in biosensing applications, RCA technique can be applied to the construction of DNA ... Selector-technique Ali, M. Monsur; Li, Feng; Zhang, Zhiqing; Zhang, Kaixiang; Kang, Dong-Ku; Ankrum, James A.; Le, X. Chris; ... This technique combines two fields: RCA, which allows nucleotide amplification, and immunoassay, which uses antibodies specific ... This amplification technique is named as Rolling circle amplification (RCA). Different from conventional DNA amplification ...
Advanced manufacturing techniques like 3d printing are being used by the researcher to fabricate them. Materials Design ... Nanozymes as well as other artificial enzymes have found wide applications, from biosensing and immunoassays, to stem cell ...
She works with the heritage sector to develop new materials and conservation techniques. She has worked with the Science Museum ... including the toxicity of nanoparticles and development of plasmonic materials for biosensing. ... where she developed in situ electrochemical systems using synchrotron radiation-based techniques. Ryan is an expert in ...
Optical detection includes fluorescence-based techniques, chemiluminescence-based techniques, and surface plasmon resonance ( ... The most common bioreceptors used in biosensing are based on antibody-antigen interactions, nucleic acid interactions, ... One common use for this technique is in detecting nucleotide mismatches in DNA because the variation in mass caused by the ... Conventional micromachining techniques such as wet etching, dry etching, deep reactive ion etching, sputtering, anodic bonding ...
... a technique called phage display). These structures have potential uses for energy storage and generation, biosensing and ... A number of techniques are available for inserting the isolated gene into the host genome. Bacteria can be induced to take up ... A number of techniques are available for inserting the isolated gene into the host genome. Recent advancements using genome ... Gene targeting techniques, which creates double-stranded breaks and takes advantage on the cells natural homologous ...
In general, SPR biosensing is demonstrating advantages over other approaches in the biomedical field due to this technique ... This makes SPR a possible technique for detecting particular substances (analytes) and SPR biosensors have been developed to ... Related complementary techniques include plasmon waveguide resonance, QCM, extraordinary optical transmission, and dual- ... Due to the versatility of SPR instrumentation, this technique pairs well with other approaches, leading to novel applications ...
This technique is convenient to study the label free and real time interactions of cells on the surface. So SPRM can be served ... Hamola, J; Vaisocherova, H; Dostalek, J; Pilarik, M (2005). "Multi-analyte surface plasmon resonance biosensing". Methods. 37 ( ... In SPRM technique, plasmon surface polariton (PSP) waves are used for illumination. In simple words, SPRI technology is an ... As is seen in the image the remarkable contrast of the image is due to the high sensitivity of the technique.[citation needed] ...
Inorganic compounds are directly formed on the surface of CNTs via a variety of techniques including electrochemical techniques ... Because of the excellent biological compatibility of Au, they are so frequently used in biosensing, medical and other related ... Hydrothermal techniques are developed in recent years. The advantage of this method is to get crystalline particles or films ... The characterization techniques of CNTs supported catalysts are varied. The most common methods include X-ray diffraction (XRD ...
Cunningham, Brian T.; Zhang, Meng; Zhuo, Yue; Kwon, Lydia; Race, Caitlin (May 2016). "Recent Advances in Biosensing With ... "Simple and Precise Preparation of a Porous Gel for a Colorimetric Glucose Sensor by a Templating Technique". Angewandte Chemie ... Emiliyanov, Grigoriy; Høiby, Poul; Pedersen, Lars; Bang, Ole (2013-03-08). "Selective Serial Multi-Antibody Biosensing with ... biosensing, diagnostics, food quality control, security, and mechanical sensing.[citation needed] Many animals in nature such ...
A stacking technique for SRRs was published in 2007 that uses dielectric spacers to apply a planarization procedure to flatten ... Other potential applications include biosensing using nanoscale particles to deflect light to angles steep enough to travel ... Nanoscale fabrication techniques exist to accomplish subwavelength geometries. Metals such as gold, silver, aluminum and copper ... Fabrication techniques include electron beam lithography, nanostructuring with a focused ion beam and interference lithography ...
By using interferometric techniques, nanometer changes can be detected. Applications for IRIS include microarray format ... is a system that can be used as a biosensing platform capable of high-throughput multiplexing of protein-protein, protein-DNA, ...
Syahir A, Usui K, Tomizaki KY, Kajikawa K, Mihara H (April 2015). "Label and Label-Free Detection Techniques for Protein ... Alongside Surface Plasmon Resonance, BLI is one of few widely available label-free biosensing technologies, a detection style ... Thus, BLI finds significant use in viscous media such as glycerol, where other techniques may struggle. Bio-layer ... Wilson JL, Scott IM, McMurry JL (November 2010). "Optical biosensing: Kinetics of protein A-IGG binding using biolayer ...
CO2 laser ablation technique is utilized to produce the first SWNHs at room temperature in absence of a metal catalyst. The CO2 ... Special designed SWNHs nanocomposites have versatile biosensing applications. One example is the sandwich nanohybrid of SWNHs- ... biosensing, drug delivery, gas storage and catalyst support for fuel cell. Single-walled carbon nanohorns are an example of the ... have been investigated by a combination of several techniques to show the electron-transfer process between the porphyrins and ...
The ability to visualize the atomic structure of surfaces and interfaces, and has applications in catalysis, biosensing and ... Techniques, and Applications. Wiley-Blackwell. ISBN 978-0471248248. Bonnell, Dawn (2013). Scanning Probe Microscopy For Energy ...
The excitation of SPPs is frequently used in an experimental technique known as surface plasmon resonance (SPR). In SPR, the ... These devices include ultra-compact plasmonic interferometers for applications such as biosensing, optical positioning and ...
Being a FET device can also be taken advantage of when using single SiNWs as biosensing devices. SiNW sensors are nanowires ... scientists who have developed new spectroscopic techniques to interrogate these molecules at the solid-liquid interface, and ... and regenerative medicine Computational and modeling approaches to biointerfaces Membranes and membrane-based biosensing ...
The nanowires have a range of advantages over silicon nanowires and the memristors may be used to directly process biosensing ... Three American patients have received whole cultured bladders with the help of doctors who use nanobiology techniques in their ... Measurement in biology using wave guide techniques, such as dual-polarization interferometry, is another example. Applications ... biosensing, biological mechanisms such as mechanosensation), nanoscience of disease (e.g. genetic disease, cancer, organ/tissue ...
Many techniques exist to detect DNA, which is usually a means to detect organisms that have that particular DNA. DNA sequences ... The use of affinity binding receptors for purposes of biosensing has been proposed by Schultz and Sims in 1979 and was ... These techniques are mainly used in agriculture, food technology and biomedicine. In medical applications biosensors are ... improved the sensitivity of IRIS through a mass tagging technique. Since initial publication, IRIS has been adapted to perform ...
Forensic techniques, Protein-protein interaction assays, Plasmonics, Optical phenomena, All stub articles, Biophysics stubs). ... "Grating coupled optical waveguide interferometer for label-free biosensing". Sensors and Actuators B: Chemical. 155 (Band 155, ...
He also developed techniques for the manipulation of biological particles. He has so far published more than 100 scientific ... Ruckstuhl, Thomas; Rankl, Michael; Seeger, Stefan (2003). "Highly sensitive biosensing using a supercritical angle fluorescence ...
The technique fuses wires as small as 10 nm. For nanowires with diameters less than 10 nm, existing welding techniques, which ... This method is investigated both for the synthesis of metallic nanowires in electronic components and for biosensing ... In one technique, the polyol synthesis, ethylene glycol is both solvent and reducing agent. This technique is particularly ... This technique allows to produce individual nanowires below 20 nm in width in a scalable way out of several metallic and metal ...
Yan Y, Shi P, Song W, Bi S (2019). "Chemiluminescence and Bioluminescence Imaging for Biosensing and Therapy: In Vitro and In ... Molecular biology techniques). ...
He is renowned for his understanding of the mechanics of materials, and for pioneering techniques that led to the study of ... Her nano-materials for biosensing have enabled the most sensitive facile enzyme detection to date and she is actively pursuing ...
This technique has high resolution and is quick, but has high equipment and material costs. This technique utilizes a DLP ... "A self-powered microfluidic origami electrochemiluminescence biosensing platform". Chemical Communications. 49 (37): 3866-3868 ... This technique is fast and low cost, but has relatively low resolution due to the isotropy of the melted wax. Inkjet printing ... This technique is low cost with high resolution, but is limited by the speed of placing one ink droplet at a time. ...
Fluorescence techniques, Cell biology, Laboratory techniques, Molecular biology techniques, Energy transfer). ... and biosensing. One common pair fluorophores for biological use is a cyan fluorescent protein (CFP) - yellow fluorescent ... FRET and FLIM Techniques. Laboratory Techniques in Biochemistry and Molecular Biology. Vol. 33. Elsevier. pp. 1-57. doi:10.1016 ... This technique can be used to determine factors affecting various types of nanoparticle formation as well as the mechanisms and ...
38 (4) 724-32 (1999) T. Ruckstuhl, M. Rankl, S. Seeger: Highly sensitive biosensing using a Supercritical Angle Fluorescence ( ... Supercritical angle fluorescence microscopy (SAF) is a technique to detect and characterize fluorescent species (proteins, ... v t e (Fluorescence techniques, Microscopy, Laser applications, All stub articles, Analytical chemistry stubs). ...
This method uses techniques such as thermal, e-beam, sputter and other traditional production technologies to deposit materials ... 3.0.CO;2-E. Thomas, D.J. (2016). "Integration of Silicon and Printed Electronics for Rapid Diagnostic Disease Biosensing". ... This is an active research area, however, and print-compatible metal deposition techniques have been demonstrated that adapt to ... 2005). "Utilizing roll-to-roll techniques for manufacturing source-drain electrodes for all-polymer transistors". Synthetic ...
Key-title: Sensing and bio-sensing research. Title proper: Sensing and bio-sensing research. ... Subject: Processes and techniques in biotechnology. Publisher: Amsterdam: Elsevier. Dates of publication: 2014- 9999 ...
Super sensitive technique to detect deadly infectious diseases. Sep 22, 2023. Nanoparticles made from plant viruses could be ... Worlds fastest camera takes a new look at biosensing. (Nanowerk News) A European consortium comprising National Physical ... Read paper in Biomedical Optics Express: Fluorescence lifetime biosensing with DNA microarrays and a CMOS-SPAD imager. ... New spin-squeezing techniques let atoms work together for better quantum measurements. Sep 25, 2023 ...
Biosensing Techniques * Cell Line, Tumor * Cell Shape* * Cell Size * Cytoskeleton / metabolism * Fibroblasts / cytology ...
"Photonic crystal enhanced fluorescence emission and blinking suppression for single quantum dot digital resolution biosensing" ...
Pentane drying The technique uses pentane as the drying liquid instead of water. In doing so the capillary stress is reduced ... Ouyang, Huimin (2005). "Biosensing using porous silicon photonic bandgap structures". In Du, Henry H (ed.). Photonic Crystals ... and Ingeborg Uhlir at the Bell Labs in the U.S. At the time, the Ulhirs were in the process of developing a technique for ... Hence, several appropriate techniques have been developed to minimize the risk of cracks formed during drying. Supercritical ...
Imaging Technique Crucial for Quality Control of Immune-targeting Antigens in Therapeutic, Diagnostic Imaging, and Bio-sensing ... Imaging Technique Crucial for Quality Control of Immune-targeting Antigens in Therapeutic, Diagnostic Imaging, and Bio-sensing ... Our antibody imaging technique will be crucial for quality control of immune-targeting antigens in therapeutic, diagnostic ... imaging, and bio-sensing applications. Moreover, the TEM methodology used in this study is readily transferable to other Y ...
Biosensing Techniques / instrumentation* * Equipment Design * Equipment Failure Analysis * HSP90 Heat-Shock Proteins / ...
Fluorescence lifetime and Time Resolved Fluorescence techniques include Forester Resonance Energy Transfer or FRET, Time ... Biosensing. *Bound vs. unbound. *Change in rate of rotation of species upon binding ... The stroboscopic optical boxcar technique is also referred to as the Strobe technique. It is a time domain, pulsed technique ... The Strobe technique is an analog technique that is inherently less sensitive than TCSPC and does not enjoy true Poisson ...
Japanese scientists report on a new biosensing protocol based on monitoring changes in optical transmittance of a solution ... Technique could help tap 2D van der Waals ferroelectrics for use in next-generation electronics Dec 04, 2023 ... Nanowerk News) Biosensing based on the detection of magnetic labels offers a rapid, sensitive and inexpensive protocol for ... A technique with the potential to enhance optical data storage capacity in diamonds. Dec 05, 2023 ...
Nowadays, the extensively used assembly techniques include drop-casting/spin-coating, Langmuir-Blodgett (LB), self-assembled ... Luminescent films for chemo- and biosensing W. Guan, W. Zhou, J. Lu and C. Lu, Chem. Soc. Rev., 2015, 44, 6981 DOI: 10.1039/ ... Luminescent films have received great interest for chemo-/bio-sensing applications due to their distinct advantages over ... Therefore, this review summarizes the recent advances in luminescent films with these assembly techniques and their ...
Biosensing Techniques; AI, Deep Learning; Ophthalmology; Remote Monitoring; Telemedicine; Breakthrough Device Designation; FDA ...
Focused on AI-Cloud Remote-Contactless Biosensing Platform and IP ... and deep learning models and statistical inference techniques. ... AIoT Biosensing Case Study: Globally vetted and deployed AIoT medical and wellness PaaS for PSG-grade contactless sleep, vital ... Fullpower-AI® is the provider of a deep learning generative AI biosensing platform. The AIoT platform is a remote sensing cloud ... Fullpower-AI® is the provider of a deep learning generative AI biosensing platform. The AIoT platform is a remote sensing cloud ...
Biosensing has only scratched the surface of its potential. Using non-intrusive, inexpensive sensors as part of a larger ... Optical sensing is one of the most prevalent biosensing techniques and, yet, we have only just begun to leverage its full ... Biosensing has only scratched the surface of its potential. Using non-intrusive, inexpensive sensors as part of a larger ... As such, biosensing results that primarily use PI values, such as pulse oximetry, arent significantly affected by ambient ...
abstract = "Monitoring biochemical interactions can serve as the basis for many diagnostic techniques.", ... Biosensing with backscattering interferometry. / Sørensen, Henrik Schiøtt; Andersen, Peter E.; Larsen, Niels Bent et al. In: ... Biosensing with backscattering interferometry. Henrik Schiøtt Sørensen, Peter E. Andersen, Niels Bent Larsen, Peter R. Hansen, ... Sørensen, H. S., Andersen, P. E., Larsen, N. B., Hansen, P. R., & Bornhop, D. J. (2009). Biosensing with backscattering ...
Biosensing Techniques. Nanowires. Biological Science Disciplines. Electrophysiology. Transistors, Electronic. Aquaculture. ...
MIE1510H: Formal Techniques in Ontology Engineering. This course will explore theoretical techniques for the design and ... Biosensing mechanisms; Design and analysis of microfluidic biosensors; Microfluidic immunosensors; Microfluidic nucleic acid ... nanomechanical testing techniques (AFM, nanoindentation, in situ SEM/TEM); atomistic modeling techniques (DFT, MD, Course- ... The techniques of deriving a discrete set of equations for continuous systems are then outlined; specifically the variational ...
Development of new types of polymer/polymerization-based biosensing and bioimaging techniques for early screening and diagnosis ... Several techniques were used in these studies such as gas pycnometry and Brunauer-Emmett-Teller (BET) (Both instruments are ... Additive manufacturing (3D printing) techniques such as binder jetting and Selective Laser Melting (SLM). (Dr. Mufeed Basti). ... NMR techniques will be included in the continuation of these studies. Two Masters students worked on these projects and they ...
Note 3) Biosensing. Biosensing refers to a set of techniques, methods, or approaches used to detect, monitor, or measure ... In biosensing, temperature drift refers to the phenomenon where changes in temperature, either in the biosensor itself or in ... Biosensing encompasses the entire process of utilizing biosensors to collect and interpret data.. (Note 4) Active-dummy ... Press release】Successful optical biosensing using dual optical combs:High sensitivity and rapid detection of biomolecules with ...
Surface-enhanced Raman scattering (SERS) is a powerful plasmonics-based analytical technique for biosensing. SERS effect relies ... Multi-technique / Multi-environment. Numerous SPM modes including AFM, conductive and electrical modes (cAFM, KPFM), STM, ... Atomic Force Microscopy (AFM) associated to Raman spectroscopy has proven to be a powerful technique for probing chemical ... An information-rich, nanoscale characterization technique is required to qualify these materials and assist in the deployment ...
... pre-compensation and receiver sides DSP techniques designed for coherent systems are introduced. ... This chapter deals with coded modulation and impairment compensation techniques in optical fiber communication. Probabilistic ... Chapter 7 Application of Fiber Optics in Bio-Sensing By Lokendra Singh, Niteshkumar Agarwal, Himnashu Bart... ... 3.1 Impairment compensation techniques at transmitter side. Pre-equalization and skew compensation are basic DSP techniques at ...
ERC-funded technique of cavity-ring-down ellipsometry (CRDE), for which we have a US and international (PCT) patents pending. ... engineering and technologyenvironmental biotechnologybiosensing. *natural sciencesphysical scienceselectromagnetism and ... 3) Biosensing companies, as the BIOCARDE instrument will be made to be compatible with (and tested with) their commercial ... 1) Research groups in the biosensing and surface characterization fields. Instruments will be sold to these groups, which will ...
Biosensing Techniques. , Biocompatible Materials. , DNA. , Nanoparticles. , Carbohydrates. Journal Title. Biosensors (Basel). ...
Individual channels can be probed electrically, as demonstrated by Neher and Sakmann in 1976 using the patch-clamp technique [ ... Precise electrochemical fabrication of sub-20 nm solid-state nanopores for single-molecule biosensing. , Journal of Physics: ... Our results thus highlight the potential of solid-state nanopore sensors for single-molecule biosensing, especially when ... Nanopore/electrode structures for single-molecule biosensing. , Electrochimica Acta, Vol: 55, Pages: 8237-8243 *Cite ...
The purpose of this review is to give an overview of recent advances in proteomic techniques for the detection and ... the discussed techniques are in general applicable to broad research field of biology and medicine, including stem cells, ... ultrasensitive techniques (Singulex, Simoa, immuno-PCR, proximity ligation/extension assay, immunomagnetic reduction assay), to ... analyses of single cells producing cytokines (ELISpot, flow cytometry, mass cytometry and emerging techniques for single cell ...
4. Microplate based biosensing with a computer screen aided technique. Open this publication in new window or tab ,,Microplate ... Microplate based biosensing with a computer screen aided technique2003In: Biosensors & bioelectronics, ISSN 0956-5663, E-ISSN ... based biosensing with a computer screen aided technique. Filippini, Daniel. Linköping University, Department of Physics, ... To demonstrate biosensing we use the hormones melatonin and α-melanocyte stimulating hormone (α-MSH) as lightening or darkening ...
The Nanobiosensor Team develops functional nanomaterials, biomaterials, biosensing devices, and standard measurement techniques ... 2 Development of ultrasensitive detection techniques for disease biomarkers * 3 Development of standard measurement techniques ... 1 Development of functional nanomaterials, biomaterials, and biosensing devices * ...
The first part of the thesis describes optical biosensing techniques based on surface-enhanced Raman spectroscopy (SERS). Our ... These results can lead to developing simple and easy biosensing methods allowing real-time biosensing applications including ... Cho, Hyunjun (2020) Real-Time Biosensing and Energy Harvesting on Human Body. Dissertation (Ph.D.), California Institute of ... a relatively high power generation and convenience of practical use can provide a real-time complementary charging technique ...
With the global rise in incidence of cancer and infectious diseases, there is a need for the development of techniques to ... Graphene oxide (GO) is an attractive template nanomaterial for such biosensing applications. Favorable properties include its ... However, a limitation of current techniques is that as-synthesized GO nanosheets are used directly in sensing applications, and ...
Laccase immobilization onto natural polysaccharides for biosensing and biodegradation. Carbohydrate Polymers, 262, 117963. ... advances in interactions between polyphenols and plant cell wall polysaccharides as studied using an adsorption technique. Food ...
Graphene Encapsulation for Cells: A Bio-Sensing and Device Platform  Salgado, Shehan (University of Waterloo, 2014-04-30) ... The generation of new nanoscale fabrication techniques is both novel and necessary for the generation of new devices and new ...

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