Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.
The discarding or destroying of liquid waste products or their transformation into something useful or innocuous.
Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.
Methods for cultivation of cells, usually on a large-scale, in a closed system for the purpose of producing cells or cellular products to harvest.
Methods for maintaining or growing CELLS in vitro.
Testing for the amount of biodegradable organic material in a water sample by measuring the quantity of oxygen consumed by biodegradation of those materials over a specific time period.
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
Devices for simulating the activities of the liver. They often consist of a hybrid between both biological and artificial materials.
Contaminated water generated as a waste product of human activity.
Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.
The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.
Condition under normal Earth gravity where the force of gravity itself is not actually altered but its influence or effect may be modified and studied. (From ASGSB Bull 1992;5(2):27)
A group of different species of microorganisms that act together as a community.
Refuse liquid or waste matter carried off by sewers.
The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
Any of several processes in which undesirable impurities in water are removed or neutralized; for example, chlorination, filtration, primary treatment, ion exchange, and distillation. It includes treatment of WASTE WATER to provide potable and hygienic water in a controlled or closed environment as well as provision of public drinking water supplies.
A gram-negative, facultatively chemoautotrophic bacterium, formerly called Wautersia eutropha, found in water and soil.
A family of gram-negative aerobic bacteria in the class BETA PROTEOBACTERIA, encompassing the acidovorans rRNA complex. Some species are pathogenic for PLANTS.
Apparatus, devices, or supplies intended for one-time or temporary use.
Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
A biocompatible polymer used as a surgical suture material.
Total mass of all the organisms of a given type and/or in a given area. (From Concise Dictionary of Biology, 1990) It includes the yield of vegetative mass produced from any given crop.
Methods of creating machines and devices.
A genus of gram-negative, aerobic, rod-shaped bacteria characterized by an outer membrane that contains glycosphingolipids but lacks lipopolysaccharide. They have the ability to degrade a broad range of substituted aromatic compounds.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
A technique for maintaining or growing TISSUE in vitro, usually by DIFFUSION, perifusion, or PERFUSION. The tissue is cultured directly after removal from the host without being dispersed for cell culture.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.
Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.
The complete absence, or (loosely) the paucity, of gaseous or dissolved elemental oxygen in a given place or environment. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
The formation of cartilage. This process is directed by CHONDROCYTES which continually divide and lay down matrix during development. It is sometimes a precursor to OSTEOGENESIS.
The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed)
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.

Antisense RNA strategies for metabolic engineering of Clostridium acetobutylicum. (1/1439)

We examined the effectiveness of antisense RNA (as RNA) strategies for metabolic engineering of Clostridium acetobutylicum. Strain ATCC 824(pRD4) was developed to produce a 102-nucleotide asRNA with 87% complementarity to the butyrate kinase (BK) gene. Strain ATCC 824(pRD4) exhibited 85 to 90% lower BK and acetate kinase specific activities than the control strain. Strain ATCC 824(pRD4) also exhibited 45 to 50% lower phosphotransbutyrylase (PTB) and phosphotransacetylase specific activities than the control strain. This strain exhibited earlier induction of solventogenesis, which resulted in 50 and 35% higher final concentrations of acetone and butanol, respectively, than the concentrations in the control. Strain ATCC 824(pRD1) was developed to putatively produce a 698-nucleotide asRNA with 96% complementarity to the PTB gene. Strain ATCC 824(pRD1) exhibited 70 and 80% lower PTB and BK activities, respectively, than the control exhibited. It also exhibited 300% higher levels of a lactate dehydrogenase activity than the control exhibited. The growth yields of ATCC 824(pRD1) were 28% less than the growth yields of the control. While the levels of acids were not affected in ATCC 824(pRD1) fermentations, the acetone and butanol concentrations were 96 and 75% lower, respectively, than the concentrations in the control fermentations. The lower level of solvent production by ATCC 824(pRD1) was compensated for by approximately 100-fold higher levels of lactate production. The lack of any significant impact on butyrate formation fluxes by the lower PTB and BK levels suggests that butyrate formation fluxes are not controlled by the levels of the butyrate formation enzymes.  (+info)

Steady-state nitrogen isotope effects of N2 and N2O production in Paracoccus denitrificans. (2/1439)

Nitrogen stable-isotope compositions (delta15N) can help track denitrification and N2O production in the environment, as can knowledge of the isotopic discrimination, or isotope effect, inherent to denitrification. However, the isotope effects associated with denitrification as a function of dissolved-oxygen concentration and their influence on the isotopic composition of N2O are not known. We developed a simple steady-state reactor to allow the measurement of denitrification isotope effects in Paracoccus denitrificans. With [dO2] between 0 and 1.2 microM, the N stable-isotope effects of NO3- and N2O reduction were constant at 28.6 per thousand +/- 1.9 per thousand and 12.9 per thousand +/- 2.6 per thousand, respectively (mean +/- standard error, n = 5). This estimate of the isotope effect of N2O reduction is the first in an axenic denitrifying culture and places the delta15N of denitrification-produced N2O midway between those of the nitrogenous oxide substrates and the product N2 in steady-state systems. Application of both isotope effects to N2O cycling studies is discussed.  (+info)

Immobilization patterns and dynamics of acetate-utilizing methanogens immobilized in sterile granular sludge in upflow anaerobic sludge blanket reactors. (3/1439)

Sterile granular sludge was inoculated with either Methanosarcina mazeii S-6, Methanosaeta concilii GP-6, or both species in acetate-fed upflow anaerobic sludge blanket (UASB) reactors to investigate the immobilization patterns and dynamics of aceticlastic methanogens in granular sludge. After several months of reactor operation, the methanogens were immobilized, either separately or together. The fastest immobilization was observed in the reactor containing M. mazeii S-6. The highest effluent concentration of acetate was observed in the reactor with only M. mazeii S-6 immobilized, while the lowest effluent concentration of acetate was observed in the reactor where both types of methanogens were immobilized together. No changes were observed in the kinetic parameters (Ks and mumax) of immobilized M. concilii GP-6 or M. mazeii S-6 compared with suspended cultures, indicating that immobilization does not affect the growth kinetics of these methanogens. An enzyme-linked immunosorbent assay using polyclonal antibodies against either M. concilii GP-6 or M. mazeii S-6 showed significant variations in the two methanogenic populations in the different reactors. Polyclonal antibodies were further used to study the spatial distribution of the two methanogens. M. concilii GP-6 was immobilized only on existing support material without any specific pattern. M. mazeii S-6, however, showed a different immobilization pattern: large clumps were formed when the concentration of acetate was high, but where the acetate concentration was low this strain was immobilized on support material as single cells or small clumps. The data clearly show that the two aceticlastic methanogens immobilize differently in UASB systems, depending on the conditions found throughout the UASB reactor.  (+info)

The role of benzoate in anaerobic degradation of terephthalate. (4/1439)

The effects of acetate, benzoate, and periods without substrate on the anaerobic degradation of terephthalate (1, 4-benzene-dicarboxylate) by a syntrophic methanogenic culture were studied. The culture had been enriched on terephthalate and was capable of benzoate degradation without a lag phase. When incubated with a mixture of benzoate and terephthalate, subsequent degradation with preference for benzoate was observed. Both benzoate and acetate inhibited the anaerobic degradation of terephthalate. The observed inhibition is partially irreversible, resulting in a decrease (or even a complete loss) of the terephthalate-degrading activity after complete degradation of benzoate or acetate. Irreversible inhibition was characteristic for terephthalate degradation only because the inhibition of benzoate degradation by acetate could well be described by reversible noncompetitive product inhibition. Terephthalate degradation was furthermore irreversibly inhibited by periods without substrate of only a few hours. The inhibition of terephthalate degradation due to periods without substrate could be overcome through incubation of the culture with a mixture of benzoate and terephthalate. In this case no influence of a period without substrate was observed. Based on these observations it is postulated that decarboxylation of terephthalate, resulting in the formation of benzoate, is strictly dependent on the concomitant fermentation of benzoate. In the presence of higher concentrations of benzoate, however, benzoate is the favored substrate over terephthalate, and the culture loses its ability to degrade terephthalate. In order to overcome the inhibition of terephthalate degradation by benzoate and acetate, a two-stage reactor system is suggested for the treatment of wastewater generated during terephthalic acid production.  (+info)

Identification of a novel group of bacteria in sludge from a deteriorated biological phosphorus removal reactor. (5/1439)

The microbial diversity of a deteriorated biological phosphorus removal reactor was investigated by methods not requiring direct cultivation. The reactor was fed with media containing acetate and high levels of phosphate (P/C weight ratio, 8:100) but failed to completely remove phosphate in the effluent and showed very limited biological phosphorus removal activity. Denaturing gradient gel electrophoresis (DGGE) of PCR-amplified 16S ribosomal DNA was used to investigate the bacterial diversity. Up to 11 DGGE bands representing at least 11 different sequence types were observed; DNA from the 6 most dominant of these bands was further isolated and sequenced. Comparative phylogenetic analysis of the partial 16S rRNA sequences suggested that one sequence type was affiliated with the alpha subclass of the Proteobacteria, one was associated with the Legionella group of the gamma subclass of the Proteobacteria, and the remaining four formed a novel group of the gamma subclass of the Proteobacteria with no close relationship to any previously described species. The novel group represented approximately 75% of the PCR-amplified DNA, based on the DGGE band intensities. Two oligonucleotide rRNA probes for this novel group were designed and used in a whole-cell hybridization analysis to investigate the abundance of this novel group in situ. The bacteria were coccoid and 3 to 4 microm in diameter and represented approximately 35% of the total population, suggesting a relatively close agreement with the results obtained by the PCR-based DGGE method. Further, based on electron microscopy and standard staining microscopic analysis, this novel group was able to accumulate granule inclusions, possibly consisting of polyhydroxyalkanoate, inside the cells.  (+info)

Fluorescence in situ hybridization using 16S rRNA-targeted oligonucleotides reveals localization of methanogens and selected uncultured bacteria in mesophilic and thermophilic sludge granules. (6/1439)

16S rRNA-targeted in situ hybridization combined with confocal laser scanning microscopy was used to elucidate the spatial distribution of microbes within two types of methanogenic granular sludge, mesophilic (35 degrees C) and thermophilic (55 degrees C), in upflow anaerobic sludge blanket reactors fed with sucrose-, acetate-, and propionate-based artificial wastewater. The spatial organization of the microbes was visualized in thin sections of the granules by using fluorescent oligonucleotide probes specific to several phylogenetic groups of microbes. In situ hybridization with archaeal- and bacterial-domain probes within granule sections clearly showed that both mesophilic and thermophilic granules had layered structures and that the outer layer harbored mainly bacterial cells while the inner layer consisted mainly of archaeal cells. Methanosaeta-, Methanobacterium-, Methanospirillum-, and Methanosarcina-like cells were detected with oligonucleotide probes specific for the different groups of methanogens, and they were found to be localized inside the granules, in both types of which dominant methanogens were members of the genus Methanosaeta. For specific detection of bacteria which were previously detected by whole-microbial-community 16S ribosomal DNA (rDNA)-cloning analysis (Y. Sekiguchi, Y. Kamagata, K. Syutsubo, A. Ohashi, H. Harada, and K. Nakamura, Microbiology 144:2655-2665, 1998) we designed probes specific for clonal 16S rDNAs related to unidentified green nonsulfur bacteria and clones related to Syntrophobacter species. The probe designed for the cluster closely related to Syntrophobacter species hybridized with coccoid cells in the inner layer of the mesophilic granule sections. The probe for the unidentified bacteria which were clustered with the green nonsulfur bacteria detected filamentous cells in the outermost layer of the thermophilic sludge granule sections. These results revealed the spatial organizations of methanogens and uncultivated bacteria and their in situ morphologies and metabolic functions in both mesophilic and thermophilic granular sludges.  (+info)

High-rate anaerobic treatment of wastewater at low temperatures. (7/1439)

Anaerobic treatment of a volatile fatty acid (VFA) mixture was investigated under psychrophilic (3 to 8 degrees C) conditions in two laboratory-scale expanded granular sludge bed reactor stages in series. The reactor system was seeded with mesophilic methanogenic granular sludge and fed with a mixture of VFAs. Good removal of fatty acids was achieved in the two-stage system. Relative high levels of propionate were present in the effluent of the first stage, but propionate was efficiently removed in the second stage, where a low hydrogen partial pressure and a low acetate concentration were advantageous for propionate oxidation. The specific VFA-degrading activities of the sludge in each of the modules doubled during system operation for 150 days, indicating a good enrichment of methanogens and proton-reducing acetogenic bacteria at such low temperatures. The specific degradation rates of butyrate, propionate, and the VFA mixture amounted to 0.139, 0.110, and 0.214 g of chemical oxygen demand g of volatile suspended solids-1 day-1, respectively. The biomass which was obtained after 1.5 years still had a temperature optimum of between 30 and 40 degrees C.  (+info)

Functional arteries grown in vitro. (8/1439)

A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. Bovine vessels cultured under pulsatile conditions had rupture strengths greater than 2000 millimeters of mercury, suture retention strengths of up to 90 grams, and collagen contents of up to 50 percent. Cultured vessels also showed contractile responses to pharmacological agents and contained smooth muscle cells that displayed markers of differentiation such as calponin and myosin heavy chains. Tissue-engineered arteries were implanted in miniature swine, with patency documented up to 24 days by digital angiography.  (+info)

... and increasing the biomass concentration in the bioreactor. Two Phase Partitioning Bioreactors are able to reduce the aqueous ... With regards to bioreactor cell growth, substrate refers to the nutrients that the cells consume and is contained within the ... Substrate inhibition in bioreactors occurs when the concentration of substrate (such as glucose, salts, or phenols) exceeds the ... Cell growth in bioreactors depends on a wide range of environmental and physiological conditions such as substrate ...
Fouling can harm the overall efficiency of the bioreactor, especially the heat exchangers. To avoid it, the bioreactor must be ... A typical bioreactor consists of following parts: Agitator - Used for the mixing of the contents of the reactor which keeps the ... These bioreactors are commonly cylindrical, ranging in size from litres to cubic metres, and are often made of stainless steel ... A bioreactor refers to any manufactured device or system that supports a biologically active environment. In one case, a ...
Algae bioreactor Bioreactor Molecular farming Photobioreactor Physcomitrella patens Hohe, A.; Reski, R. (2005). "From axenic ... The moss bioreactor is used to cultivate moss in a suspension culture in agitated, and aerated liquid medium. The culture is ... A moss bioreactor is a photobioreactor used for the cultivation and propagation of mosses. It is usually used in molecular ... The first moss bioreactors for the model organism Physcomitrella patens were developed in the 1990s to comply with the safety ...
An algae bioreactor is used for cultivating micro or macro algae. Algae may be cultivated for the purposes of biomass ... Specifically, algae bioreactors can be used to produce fuels such as biodiesel and bioethanol, to generate animal feed, or to ... The bioreactor has to be made out of transparent material. It has been documented that the first microalgae cultivation was ... Bioreactors can be divided into two broad categories, open systems and photobioreactors (PRB). The difference between these two ...
In the immersed Membrane Bioreactor (iMBR) configuration, the filtration element is installed in either the main bioreactor ... "Membrane bioreactor and integrated membrane bioreactor systems for micropollutant removal from wastewater: A review". Journal ... Membrane Bioreactors Archived 2008-03-08 at the Wayback Machine. membrane.unsw.edu.au Z.F. Cui; S. Chang; A.G. Fane (2003). " ... Membrane bioreactors can be used to reduce the footprint of an activated sludge sewage treatment system by removing some of the ...
... s are a relatively new technology. For the newly developed bioreactor landfills initial monitoring costs are ... 2006). Bioreactor.org - General Info. Retrieved February 3, 2010, from Bioreactor.org: [3] Murphyb, S. R. (1992). A lysimeter ... Bioreactor landfills produce lower quantities of VOCs than traditional landfills, except H2S. Bioreactor landfills produce ... Bioreactor landfills are expected to increase this rate of decomposition and save up to 30% of space needed for landfills. With ...
A single-use bioreactor or disposable bioreactor is a bioreactor with a disposable bag instead of a culture vessel. Typically, ... Other single-use bioreactors are agitated by a rocking motion. This type of bioreactor does not need any mechanical agitators ... Some single-use bioreactors use stirrers like conventional bioreactors, but with stirrers that are integrated into the plastic ... A complete life cycle assessment comparing single-use bioreactors and conventional bioreactors does not exist, but many ...
The in vivo bioreactor is a tissue engineering paradigm that uses bioreactor methodology to grow neotissue in vivo that ... Yet another study pushed the limits of the in vivo bioreactor by proving that the omentum is suitable as a bioreactor space and ... a bioreactor space will be created between tissue layers through the use of hydrogel injections to create a bioreactor space. ... The in vivo bioreactor depends on harnessing the reparative qualities of the body to recruit stem cells into an implanted ...
One such technological development was the hollow fiber bioreactor. Hollow fiber bioreactors are used to generate high ... the hollow fiber bioreactor technology was found comparable in its production capacity to that of other commercial bioreactors ... Smaller hollow fiber bioreactors are often used for selection and optimization of cell lines prior to stepping up to larger ... A Hollow fiber bioreactor is a 3 dimensional cell culturing system based on hollow fibers, which are small, semi-permeable ...
... or AnMBR is the name of a technology utilized in wastewater treatment. AnMBR works by using a ... Water treatment, Environmental engineering, Sanitation, Sewerage, Bioreactors, Membrane technology). ... membrane bioreactor (MBR). The sewage is filtered and separated leaving the effluent and sludge apart. This sludge is treated ...
doi:10.1016/0168-1656(94)90008-6. (Bioreactors). ...
... bioreactors may be followed by a physical phase separation to remove biological solids from the treated ... Membrane bioreactors (MBR) are activated sludge systems using a membrane liquid-solid phase separation process. The membrane ... The technology permits bioreactor operation with considerably higher mixed liquor suspended solids (MLSS) concentration than ... Fixed-film or attached growth secondary treatment bioreactors are similar to a plug flow reactor model circulating water over ...
1000 liters Bioreactors. Vialing Station. In January 2009, JNIMC acquired Biocor vaccine manufacture facilities, a subsidiary ...
Denitrifying woodchip bioreactor have a low construction and operational costs with a comparatively long lifespan going up to ... Woodchips can be loaded into a 'denitrifying woodchip bioreactor' which has been used for several decades as an emerging ... They may also be used as an organic mulch in gardening, landscaping, and ecosystem restoration; in bioreactors for ...
"Adherent Cell Culture Bioreactors , Esco VacciXcell". escovaccixcell.com. Retrieved 2022-12-02. "Adherent versus suspension ...
"Anaerobic Bioreactors Becoming Economical". Water Technology. 2 (4). July 1994. "Researchers Engineer New Methane-production ... In 1985, Shimizu Construction developed a bioreactor that uses Methanosarcina to treat waste water from food processing plants ... According to a 1994 report in Chemistry and Industry, bioreactors utilizing anaerobic digestion by Methanothrix soehngenii or ...
This bioreactor has two compartments: The anode, where the oxidation reaction takes place; And the cathode, where the reduction ... A Bioelectrochemical reactor is a type of bioreactor where bioelectrochemical processes are used to degrade/produce organic ... In Subnautica, the player can build a bioreactor that serves the same purpose as a bioelectrochemical reactor. ...
Decker, E. L.; Reski, R. (2007). "Moss bioreactors producing improved biopharmaceuticals". Current Opinion in Biotechnology. 18 ... implications for crop improvement or human health and the safe production of complex biopharmaceuticals in the moss bioreactor ...
In 2011, Reski and coworkers produced recombinant, biologically active human factor H in a moss bioreactor. In 2017 the first ... In the same year, Reski invented the moss bioreactor and founded "greenovation Biotech GmbH", a biotechnology company utilizing ... Editorial board Biology International The Reski Lab Publications Reski Lab on Twitter "Moss bioreactors do not smell" - ... Decker, Eva L.; Reski, Ralf (2007). "Moss bioreactors producing improved biopharmaceuticals". Current Opinion in Biotechnology ...
automated cell banking (cryovial handling) system Single-use bioreactors Scaledown bioreactors Membrane chromatography devices ... BBI, the world's leading manufacturer of fermenters (bioreactor) and cell culture systems at the time, was integrated into the ... "Sartorius, Nova to Combine Bioreactor and Cell Analyzer Platforms". GEN News Highlights. Genetic Engineering & Biotechnology ... Sartorius Stedim Biotech's 2nd-Generation STR Bioreactors. Retrieved 2 December 2017. Zijlstra, Gerben; Gupta, Priyanka (15 ...
Eva L. Decker & Ralf Reski (2007). "Moss bioreactors producing improved biopharmaceuticals". Current Opinion in Biotechnology. ... Moss bioreactor with P. patens Four different ecotypes of P. patens stored at the International Moss Stock Center Protonema ... implications for crop improvement or human health and the safe production of complex biopharmaceuticals in moss bioreactors. By ...
Woodlawn Bioreactor. The parish has begun to be used as commuter zone for the nearby city of Canberra. The Woodlawn Wind Farm ...
Biological hydrogen can be produced in an algae bioreactor. In the late 1990s it was discovered that if the algae are deprived ... Biohydrogen can be produced in bioreactors. The process involves bacteria consuming hydrocarbons and producing hydrogen and CO2 ...
Hu, Wei-Shou; Dodge, Timothy C. (December 1985). "Cultivation of Mammalian Cells in Bioreactors". Biotechnology Progress. 1 (4 ...
They produce trachea scaffolds and bioreactors. Biostage has litigation over wrongful death pending that may affect Harvard ...
Bacteria digest waste in the lowest portion of the upflow reactor; the bioreactor zone. In between these two stages is the ...
"Pharmaceutical bioreactor / fermentor". American Pharmaceutical Review. Retrieved 7 July 2021. Ahmad B, Rehman MU, Amin I, Arif ... scale up of production is feasible at reasonable cost because the producing microorganism can be cultured in a bioreactor. ...
By 2001, the Aspen seep bioreactor treated 2.5 million gallons of ARD. The design evolved over time and in 2003, at the behest ... "Compost-Free Bioreactors Remove Metals from Acid Rock Drainage." Technology News and Trends. U.S. Environmental Protection ... In 1993 the State of California set up a pilot scale one-cell bioreactor with manure substrate for AMD treatment at Leviathan ... The sulfide effluent is passed into Bioreactor No. 2 for additional metal removal. Next, sodium hydroxide is added to the ...
... (EBR) is a type of a bioreactor used in water treatment. EBR is a high-efficiency denitrification, ... Higgins, J.; Mattes, A.; Stiebel, W.; Wootton, B. (2017). Eco-Engineered Bioreactors: Advanced Natural Wastewater Treatment. ... In conventional bioreactors, these electrons are provided by excess organic electron donors (e.g., organic carbon sources such ... metals, and inorganics removal technology that provides electrons directly to the EBR bioreactor as a substitute for using ...
Cyanobacteria bioreactors require high energy to operate. Cultures require constant mixing, and the harvesting of biosynthetic ... This susceptibility could potentially shut down entire bioreactors. Furthermore, the native reaction pathway for isobutanol in ... helping prevent contamination during growth in industrial bioreactors. S. cerevisiae cannot be affected by bacteriophages ...
An algae-powered bioreactor, called the Photobioreactor, arrived at the International Space Station on May 6 and represents a ... Algae Bioreactor on Space Station Could Make Oxygen, Food for Astronauts. By Samantha Mathewson ... The algae-powered bioreactor, called the Photobioreactor, represents a major step toward creating a closed-loop life-support ... Astronauts on the International Space Station will begin testing an innovative algae-powered bioreactor to assess its ...
The study on global bioreactors market includes volume market for stainless steel, single-use and glass bioreactors. Factors ... The global bioreactors market is expected to reach to USD 1,417 Million by 2021 from USD 955 Million in 2015, at a CAGR of 6.8 ... Bioreactors Market by Scale Range (20L, 1500L), Material (Single-Use, Stainless Steel), Usage (Lab Scale, Pilot Scale, Full ... The global bioreactor market is fragmented and competitive, with a significant number of global and regional market players. ...
USGS 444049087424303 GLRI BIOREACTOR OUTLET NR DUVALL, WI. PROVISIONAL DATA SUBJECT TO REVISION. Available data for this site ...
Hollow Fiber Bioreactor Systems Increase Cell Culture Yield. One of the most important advances in the field of cell biology ...
ORCID: 0000-0003-2944-4839 (2012) Micro-bioreactors controlled with photonic ionogel actuators. In: The Technology Touchdown ...
A Novel, Membrane-Based Bioreactor Design to Enable a Closed-Loop System on Earth and Beyond. Award Information ... The proposed design is a novel, membrane-based bioreactor that will enable bacterial growth and biopolymer production to occur ... The proposed innovation is a membrane bioreactor system to produce a biopolymer from methane gas. This new methane fermentation ... Mango Materials will partner with Colorado School of Mines where there is extensive experience with membrane bioreactors, to ...
Additionally, we will introduce the use of feeding techniques bioreactors and have a glance on shakers too.. Date & Time. * ... You will also learn how to optimize your process in shake flasks and bioreactors via proper choice of vessel type, vessel ... Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells in suspension ... Learn about feeding possibilities in shake flasks & bioreactors and their impact on your culture ...
IKA HA.gv.sw.0.5 Glass Vessel, Single-Wall Bioreactors 20105898. Manufacturer: IKA. Model: ika-20105898. Condition: New. ...
San, Ka-Yiu (1984) Studies on the On-Line Identification and Optimal Control of Bioreactors. Dissertation (Ph.D.), California ...
Bioreactor pH & DO Probes*Bioreactors*Bottle Assemblies*Bottles, Media and Storage*Bottles, Transfer Feed*Flasks, Erlenmeyer* ... Bioreactors*Blocks*Bottles, Carboys & Jars*Calibration Weights*Carts*Cell Culture*Celltreat Plastics*Centrifuge*CG BioSciences* ... This pre fabricated, single use bio reactor kit consists of the 8 components listed. They are packed in an ISO Class 7 clean ... These pre-assembled kits can be customized to any validated components currently specified on your bioreactor design.. Please ...
The role of Mn++ ions for high and consistent yield of citric acid in recycling fed-batch bioreactor system and its novelty on ... The role of Mn++ ions for high and consistent yield of citric acid in recycling fed-batch bioreactor system and its novelty on ... The role of Mn++ ions for high and consistent yield of citric acid in recycling fed-batch bioreactor system and its novelty on ... The role of Mn++ ions for high and consistent yield of citric acid in recycling fed-batch bioreactor system and its novelty on ...
Podcast: Bioreactors. Published On: June 16, 2016,By Illinois Soybean Association,Categories: Conservation Practices, Water ... Bioreactors are an edge-of-field filtration system that reduce the nitrate levels in water flowing out of fields and into ... Christianson says bioreactors have the potential to be one of the most effective tools for farmers looking for ways to reduce ... University of Illinois Assistant Professor of Water Quality, Laura Christianson, Ph.D., goes in-depth on bioreactors. ...
The global "Membrane Bioreactor Market size is projected to reach USD 4.9 billion by 2026 at a CAGR of 8.3% between 2021 and ... Dont miss out on business opportunities in Membrane Bioreactor Market.. Speak to Our Analyst and gain crucial industry ... "Membrane Bioreactor Market". There is an increase in demand for MBRs for municipal as well as industrial wastewater treatment ... https://www.prnewswire.com/news-releases/membrane-bioreactor-market-worth-4-9-billion-by-2026--exclusive-report-by- ...
Bioreactors / Fermentors * Laboratory Bioreactors / Fermentors * Pilot Plant Bioreactors / Fermentors * Industrial Bioreactors ... Bioreactors / Fermentors * Laboratory Bioreactors / Fermentors * Pilot Plant Bioreactors / Fermentors * Industrial Bioreactors ... Bioreactors / Fermentors * Laboratory Bioreactors / Fermentors * Pilot Plant Bioreactors / Fermentors * Industrial Bioreactors ... Bioreactors / Fermentors * Laboratory Bioreactors / Fermentors * Pilot Plant Bioreactors / Fermentors * Industrial Bioreactors ...
Microbial bioreactors are intended to create a relatively steady environment that are suitable for microbial fermentation with ... Microbial bioreactors are intended to create a relatively steady environment that are suitable for microbial fermentation with ... Featuring 3.3 high borosilicate glass and premium SS304/316L stainless steel, our bioreactors always use the best materials. ...
BIOSTAT Cplus Bioreactors •Microbial Package •20 Liter Culture Vessel Bio Reacting •Stainless Steel Fermenting Tank with Power ... Braun Biostat C Bioreactor •Thermostat System and Air… ... Lot of (12) - B. Braun Biostat C Bioreactor. •Thermostat System ... 1000 LITER BIOREACTOR. Uses disposable single-use bioreactor bags, which eliminates the timely need for cleaning. This system ... WAVE 20/50 EH BIOREACTOR. Modular bioreactor platform designed for use with disposable chambers. Suitable for R&D as well as ...
Solida Biotech is a manufacturer of Bioreactors and Fermenters for fermentation and cell culture. We produce innovative modular ... Pilot & Industrial SIP bioreactors. SIP stainless steel in situ sterilisable and CIPable bioreactors, from 20 litres up to 50 ... Compact bioreactors. A compact laboratory bioreactor solution characterised by great performance and ease of use, the perfect ... Photo bioreactors. Laboratory, pilot and open field large scale photo-bioreactors. Customisable PBR systems are available in ...
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Bioreactors HB+Architects an interdisciplinary Architectural studio based in San Francisco ... A clear answer to the worlds trash and landfill problem is this concept behind bio-reactors. In a bio-reactor liquid from ... A bioreactor can be aerobic or anaerobic or possibly a hybrid of the two. In an aerobic process leachate is piped to storage ... An average size bio-reactor can feed energy to power up to 500 homes, and with these becoming the norm, you can only imagine ...
Now, newer bioreactor setups use macro spargers to introduce large bubbles of air or nitrogen. These bubbles dont dissolve ... In larger bioreactors, this can decrease cell viability and product titer.. More effective: Combining pumping base and sparging ... At the beginning of a bioreactor run, the buffer in the culture medium keeps the pH at the desired levels. Carbon dioxide may ... The traditional method of controlling pH involves pumping base into a bioreactor during the early stages of a cell culture and ...
Bioreactors/fermenters: process control in enzyme production. - Bioreactors/fermenters: control of culture growth ... Simple sensor exchange in your bioreactor/fermenter can be performed in seconds thanks to the lockable bayonet connector and ... Digital pH electrodes for bioreactors and biotechnology production processes with ion. trap for long-term stable reference ... Memosens glass electrode for bioreactors in the biotech industry and for the food industry. ...
The products include animal cells or plant cell bioreactor, photo bioreactor,solid state fermentor, airlift fermentor, Mini ... KNIK BIO specializes in providing bioreactors and fermentors with control system from lab to production line in range of 0.1L- ... bioreactor, pilot fermentor,industrial fermenter and control system, etc.. ... fermenter and bioreactor Ecuador manufacturer with years experience, from China.We mainly provide fermenter and bioreactor ...
Get an overview of the advantages and disadvantages of Wave Bioreactors and their importance in the development of innovative ... the different parts and types of Wave Bioreactors, and their wide range of applications in fields such as cell cultivation, ... Learn about the latest technology in bioprocessing with Wave Bioreactor. Discover the principle behind the mechanical waves ... Wave Bioreactor - Principle, Parts, Types, Uses. Working Principle of Wave Bioreactor. The wave bioreactor is an innovative ...
Technical Data of IKA HA.vh.5 Vessel Holder Bioreactors. Height. 465 mm. ...
Zarmi, Y. ; Bel, G. ; Aflalo, C. / Theoretical Analysis of Culture Growth in Flat-Plate Bioreactors : The Essential Role of ... Zarmi, Y., Bel, G., & Aflalo, C. (2013). Theoretical Analysis of Culture Growth in Flat-Plate Bioreactors: The Essential Role ... Theoretical Analysis of Culture Growth in Flat-Plate Bioreactors: The Essential Role of Timescales. / Zarmi, Y.; Bel, G.; ... Zarmi, Y, Bel, G & Aflalo, C 2013, Theoretical Analysis of Culture Growth in Flat-Plate Bioreactors: The Essential Role of ...
Pilot Bioreactor System Production scale multifermentors Benchtop Bioreactor Systems In-situ bioreactors and fermentors Web ... In-situ sterilizable bioreactors and fermentors. Stainless steel, in-situ sterilizable bioreactors in 5-20 L volumes. ... Small-scale Parallel Bioreactors. Simultaneous functions with unique process parameter settings. High-throughput bioreactor ... In situ sterilizable bioreactors and fermentors, Microbial cell cultivation, fermentor, Magnetic stirring bioreactor, Automated ...
Railway bioreactor toilet cleaning system BioUnit. *Specially designed for cleaning on-board bioreactor wastewater treatment ... Cleaning bioreactor toilets made easy How to use the BioUnit. The BioUnit is a special cleaning device to service advanced ... Bioreactor toilet cleaning system BioUnit M. The BioUnit Mobile is designed as a mobile solution. It can be used for ... Bioreactor toilet cleaning system BioUnit S. The BioUnit S is designed as stationary solution for medium to large railway ...
1250 L Algae Bioreactor designed to reliably grow algae in industrial or commercial uses. The equipment is ideal for biotech ...
Refurbished Wave Biotech Base 20/50EH Bioreactor System, tested & serviced prior to shipping. Up to a 1-year Warranty & ... The Wave Biotech Base 20/50EH Bioreactor System is a single use bioreactor system. ... New Brunswick / Eppendorf CelliGen BLU Bioreactor Model: BLU-120-LSA. Item: 30080More Info ... Sartorius Stedim Biotech BIOSTAT CultiBag RM 50 Bioreactor. Item: 30350More Info ...
  • Simple sensor exchange in your bioreactor/fermenter can be performed in seconds thanks to the lockable bayonet connector and automatic sensor identification. (endress.com)
  • fermenter and bioreactor Ecuador manufacturer with years' experience, from China.We mainly provide fermenter and bioreactor Ecuador with top quality and competitive value.we have an expert fermenter and bioreactor Ecuador solution designers.Our solution is by means of the national expert certification. (knikbio.com)
  • Mango Materials will partner with Colorado School of Mines where there is extensive experience with membrane bioreactors, to design and construct this system. (sbir.gov)
  • Application of deep learning for predicting the treatment performance of real municipal wastewater based on one-year operation of two anaerobic membrane bioreactors. (cdc.gov)
  • A bioreactor can be aerobic or anaerobic or possibly a hybrid of the two. (hbaarchitects.com)
  • A Hybrid bioreactor accelerates decay with both aerobic-anaerobic treatment. (hbaarchitects.com)
  • nov., a mesophilic, non-spore-forming bacterium isolated from a lab-scale methanogenic landfill bioreactor digesting anaerobic sludge, and emendation of the genus Lutispora to include species which are non-spore-forming and mesophilic. (bvsalud.org)
  • A novel anaerobic, mesophilic, non- spore -forming bacterium ( strain m25T) was isolated from methanogenic enrichment cultures obtained from a lab-scale methanogenic landfill bioreactor containing anaerobic digester sludge . (bvsalud.org)
  • They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. (bvsalud.org)
  • The company was founded by a management team with over 20 years' experience in the fields of fermentation, cell culture, sterile processing, software and automation technologies, with the aim of meeting the challenges of producing and supplying leading industrial and institutional customers with a new generation of bioreactors and fermenters for research and production, as well as scientific instruments. (solidabiotech.com)
  • We offers a wide range of compact and modular bioreactors and fermenters from 50ml to 50 cubic metre pilot and industrial plants and integrated turn-key solutions. (solidabiotech.com)
  • The study on global bioreactors market includes volume market for stainless steel, single-use and glass bioreactors. (marketsandmarkets.com)
  • Factors such as the increase in adoption of single-use technologies, use of hybrid technologies: single-use and stainless steel, growing popularity of single-use bioreactor among biopharmaceutical companies, and growing biologics market are fueling the growth of this market. (marketsandmarkets.com)
  • Featuring 3.3 high borosilicate glass and premium SS304/316L stainless steel, our bioreactors always use the best materials. (lab1st.com)
  • Versatile modular system for autoclavable Bioreactors from 50mL to 30 Litres w/v, Disposable from 250mL to 75 liters w/v and in Stainless Steel from 1L to 100 Litres w/v. (solidabiotech.com)
  • Modular Laboratory SIP stainless steel in situ sterilisable bioreactors, from 1 litre up to 50 litre w/v as well as custom fit solutions. (solidabiotech.com)
  • SIP stainless steel in situ sterilisable and CIPable bioreactors, from 20 litres up to 50 cubic metres, custom fit and turn-key integrated solutions. (solidabiotech.com)
  • It is typically made of glass, stainless steel, or plastic, and is designed to be compatible with the specific type of wave bioreactor. (microbiologynote.com)
  • An Anerobic bioreactor landfill operates by adding water with leachate and other sources, this process encourages decay in the absence of oxygen and produces Methane which is captured to fuel energy sources. (hbaarchitects.com)
  • Both being tremendous advantages of a bioreactor over a traditional landfill. (hbaarchitects.com)
  • Methane in a bioreactor is produced at a much faster rate than a traditional landfill, therefore, key is the efficiency of a system that traps and transports Methane. (hbaarchitects.com)
  • The global bioreactors market is expected to reach to USD 1,417 Million by 2021 from USD 955 Million in 2015, at a CAGR of 6.8% between 2015 and 2021. (marketsandmarkets.com)
  • The global " Membrane Bioreactor Market size is projected to reach USD 4.9 billion by 2026 at a CAGR of 8.3% between 2021 and 2026. (sngine.com)
  • Modular bioreactor platform designed for use with disposable chambers. (surplussolutionsblog.com)
  • Modular bioreactors concept guarantees minimal service downtime and rapid modules replacement. (solidabiotech.com)
  • Latest generation Modular Bioreactors, developed with industrial automation to provide greater speed, power and expandability for laboratory, pilot, and industrial scale up processes. (solidabiotech.com)
  • Parallel bioreactor systems for advanced bioprocess control and highly efficient process development. (solidabiotech.com)
  • Single-use Bioprocess Bags, Bioreactors, Containers and Mixing Systems 50 mL to 3,000 L volume. (solidabiotech.com)
  • Bioreactors need to mimic these features to ensure the cells can thrive. (alicat.com)
  • This is done by generating periodic and oscillatory motions in the bioreactor vessel, which can mimic the natural environment of cells and improve cell growth and productivity. (microbiologynote.com)
  • The proposed innovation is a membrane bioreactor system to produce a biopolymer from methane gas. (sbir.gov)
  • The proposed design is a novel, membrane-based bioreactor that will enable bacterial growth and biopolymer production to occur in microgravity environments on moist membranes that are sandwiched between layers of the gaseous feedstocks methane and oxygen. (sbir.gov)
  • Astronauts on the International Space Station will begin testing an innovative algae-powered bioreactor to assess its feasibility for future long-duration space missions. (space.com)
  • The algae-powered bioreactor, called the Photobioreactor, represents a major step toward creating a closed-loop life-support system, which could one day sustain astronauts without cargo resupply missions from Earth. (space.com)
  • Wave Bioreactors are also used in applications such as algae cultivation, where the technology can be used to increase biomass productivity and improve the quality of the algae. (microbiologynote.com)
  • This includes attaching all the necessary parts and components to the bioreactor vessel, and making sure that all the connections are secure. (microbiologynote.com)
  • The present investigation deals with a novel technique for high and consistent yield of citric acid in a fed-batch bioreactor of 9-L working volume. (ejbiotechnology.info)
  • A high production yield of S1RBD varying between 4mg and 70 mg per liter of crude cell culture supernatant was achieved, respectively, in shake-flasks and in 7L-bioreactor. (bvsalud.org)
  • New product launches, FDA approval, and acquisitions are some of the key strategies adopted by the market players to achieve growth in the bioreactor market. (marketsandmarkets.com)
  • Membrane Bioreactor Market to Witness Unprecedented Growth in. (sngine.com)
  • The traditional method of controlling pH involves pumping base into a bioreactor during the early stages of a cell culture and then using sparging gases during the exponential growth phase. (alicat.com)
  • Versatile bioconsole for autoclavable Bioreactors from 50mL to 30 litres working volume and Disposable from 250mL to 75 litres w/v. (solidabiotech.com)
  • This type of bioreactor combines two or more of the above technologies to create a more efficient and versatile bioreactor. (microbiologynote.com)
  • Now, newer bioreactor setups use macro spargers to introduce large bubbles of air or nitrogen. (alicat.com)
  • These bubbles don't dissolve easily, so they strip the carbon dioxide from the culture, bringing it to the headspace of the bioreactor where it is removed. (alicat.com)
  • The wave bioreactor is an innovative technique for cultivating cell cultures. (microbiologynote.com)
  • The importance of the Wave Bioreactor is that it offers several advantages over traditional static or stirred bioreactors, such as improved oxygenation and mass transfer, reduced shear stress on the cells, and enhanced mixing and mixing of the culture media. (microbiologynote.com)
  • This system allows the operator to control and monitor the various parameters of the bioreactor, such as temperature, pH, and oxygen levels. (microbiologynote.com)
  • Additionally, Wave Bioreactors can be used in a variety of applications, such as cell cultivation, protein production, and gene therapy. (microbiologynote.com)
  • A simple solution is to pump base into the bioreactor using direct feedback from pH sensors. (alicat.com)
  • The wave generator can be a magnetic coil, ultrasonic transducer, or a pump, depending on the specific type of wave bioreactor. (microbiologynote.com)
  • A Wave Bioreactor (WBR) is a type of bioreactor that uses mechanical waves to agitate and mix the culture media and cells. (microbiologynote.com)
  • With the increase in demand for sustainable products and biofuels, Wave Bioreactor technology is becoming more important for the development of innovative bioprocesses. (microbiologynote.com)
  • The choice of the type of wave bioreactor depends on the type of application, culture media, and cells. (microbiologynote.com)
  • Some wave bioreactors may have additional parts or features, such as a mixing system or a gas-tight sealing, depending on the specific type and model of the bioreactor, and the requirements of the application. (microbiologynote.com)
  • Single and parallel bioreactors enable you to control between one and 36 bioreactors working online simultaneously and independently. (solidabiotech.com)
  • A compact laboratory bioreactor solution characterised by great performance and ease of use, the perfect way to get started. (solidabiotech.com)
  • Bioreactors are an edge-of-field filtration system that reduce the nitrate levels in water flowing out of fields and into waterways. (ilsoyadvisor.com)
  • This system allows the operator to sterilize the bioreactor and its components before and after use, to prevent contamination. (microbiologynote.com)
  • The global bioreactor market is fragmented and competitive, with a significant number of global and regional market players. (marketsandmarkets.com)
  • Leading players in the bioreactor market have adopted various strategies to expand their global presence and increase their market shares. (marketsandmarkets.com)
  • This helped the company to expand its business and product offerings in the bioreactor market. (marketsandmarkets.com)
  • Don't miss out on business opportunities in Membrane Bioreactor Market . (sngine.com)
  • These problems compound as bioreactor size increases, meaning that pumping base simply doesn't scale up well. (alicat.com)
  • Mixing time and agitation both need to increase with bioreactor size to avoid worsening localization, but this comes at the expense of increased foam and shear stress. (alicat.com)
  • These pre-assembled kits can be customized to any validated components currently specified on your bioreactor design. (chemglass.com)
  • In larger bioreactors, this can decrease cell viability and product titer. (alicat.com)
  • cell density at infection 2-3x 106 cells/mL and time post-infection (tpi or harvest time) of 72h and 72-96 h successively for expression in shake-flasks and 7L-bioreactor. (bvsalud.org)
  • For a high product titer, the pH needs to be constant in the entire bioreactor, which requires thorough mixing. (alicat.com)
  • University of Illinois Assistant Professor of Water Quality, Laura Christianson, Ph.D., goes in-depth on bioreactors. (ilsoyadvisor.com)
  • Hydrogen sulfide was generated in a sulfate reduction bioreactor and was used to precipitate metal sulfides from the mine water in a separate reactor. (cdc.gov)
  • The metal-depleted, sulfate-rich mine water then passed through a limestone-filled reactor to raise its pH before entering the bioreactor. (cdc.gov)
  • At the beginning of a bioreactor run, the buffer in the culture medium keeps the pH at the desired levels. (alicat.com)
  • This type of bioreactor uses magnetic fields to generate the mechanical waves that agitate the culture media and cells. (microbiologynote.com)
  • This type of bioreactor uses acoustic waves to agitate the culture media and cells, the waves are generated by sound sources such as speakers. (microbiologynote.com)
  • Like-for-like replacement parts for Applikon® Biotechnology and Broadley-James® brands of bioreactors. (chemglass.com)
  • Christianson says bioreactors have the potential to be one of the most effective tools for farmers looking for ways to reduce nutrient runoff. (ilsoyadvisor.com)
  • Sartorius AG (U.S.) is a leading Original Equipment Manufacturers (OEMs) supplier of bioreactors. (marketsandmarkets.com)
  • Microbial bioreactors are intended to create a relatively steady environment that are suitable for microbial fermentation with multiple parameters controlling and automatic procedures. (lab1st.com)
  • This type of bioreactor uses a cyclical pressure change to generate the mechanical waves. (microbiologynote.com)