Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
Surgical insertion of synthetic material to repair injured or diseased heart valves.
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
The pathologic narrowing of the orifice of the TRICUSPID VALVE. This hinders the emptying of RIGHT ATRIUM leading to elevated right atrial pressure and systemic venous congestion. Tricuspid valve stenosis is almost always due to RHEUMATIC FEVER.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
The plan and delineation of prostheses in general or a specific prosthesis.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
The fitting and adjusting of artificial parts of the body. (From Stedman's, 26th ed)
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
Reference points located by visual inspection, palpation, or computer assistance, that are useful in localizing structures on or within the human body.
The valve between the left atrium and left ventricle of the heart.
Removal of an implanted therapeutic or prosthetic device.
Any type of abortion, induced or spontaneous, that is associated with infection of the UTERUS and its appendages. It is characterized by FEVER, uterine tenderness, and foul discharge.
The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.
Pathologic deposition of calcium salts in tissues.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)
Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).
Elements of limited time intervals, contributing to particular results or situations.
Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
An island in the Gulf of St. Lawrence constituting a province of Canada in the eastern part of the country. It is very irregular in shape with many deep inlets. Its capital is Charlottetown. Discovered by the French in 1534 and originally named Ile Saint-Jean, it was renamed in 1799 in honor of Prince Edward, fourth son of George III and future father of Queen Victoria. (From Webster's New Geographical Dictionary, 1988, p981 & Room, Brewer's Dictionary of Names, 1992, p433)

Destructive aortic valve endocarditis from Brucella abortus: survival with emergency aortic valve replacement. (1/643)

Brucella abortus infection of the aortic valve caused acute aortic regurgitation leading to severe left ventricular failure in a 62-year-old man. He made an excellent recovery after emergency aortic valve replacement. This is the third reported case of successful heart valve replacement for Brucella endocarditis and the second such case involving the aortic valve.  (+info)

Long-term survival and valve-related complications in young women with cardiac valve replacements. (2/643)

BACKGROUND: The type of cardiac valve replacement associated with the lowest health risks for young women who may undergo pregnancies is unknown. We investigated which valve type was associated with greatest patient and valve survival and the effect of pregnancy on valve loss. METHODS AND RESULTS: In this retrospective study, all women 12 to 35 years old who underwent valve replacements between 1972 and 1992 at Greenlane Hospital were identified, and follow-up was available in 93%. The 232 women were followed up for 1499 patient-years. Ten-year survival of women with mechanical (n=178), bioprosthetic (n=73), and homograft (n=72) valves was 70% (95% CI, 59% to 83%), 84% (95% CI, 72% to 99%), and 96% (95% CI, 91% to 100%), P=0.002. After adjustment for confounding variables, the relative risk (RR) of death with mechanical compared with bioprosthetic valves was 2.17 (95% CI, 0.78 to 5.88). Thromboembolic events occurred in 45% of women with mechanical valves within 5 years, compared with 13% with bioprosthetic valves, P=0.0001. Valve loss at 10 years was higher in bioprosthetic valves [82% (95% CI, 62% to 92%)] than in mechanical [29% (95% CI, 17% to 39%)] or homograft [28% (95% CI, 12% to 41%)] valves, P=0.0001. Pregnancy was not associated with increased bioprosthetic (RR, 0.96; 95% CI, 0.68 to 1. 35), homograft (RR, 0.65; 95% CI, 0.37 to 1.13), or mechanical (RR, 0.54; 95% CI, 0.27 to 1.08) valve loss. CONCLUSIONS: Although 10-year valve survival was greater with mechanical than bioprosthetic valves, mechanical valves may be associated with reduced patient survival in young women. Thromboembolic complications, often with long-term sequelae, were common with mechanical valves. Pregnancy did not increase structural deterioration or reduce survival of bioprosthetic valves.  (+info)

Haemodynamic performance of aortic pericardial bioprostheses and bileaflet prostheses at rest and during exercise: implications for the surgical management of patients with small aortic roots. (3/643)

OBJECTIVE: To determine the haemodynamic behaviour, at rest and during exercise, of aortic valve pericardial bioprostheses and different sizes of bileaflet prosthesis. DESIGN: Observational study. SETTING: Tertiary medical centre. PATIENTS AND INTERVENTIONS: 74 patients (33 women, 41 men; mean age 64 years) in whom 40 pericardial bioprostheses and 34 bileaflet prostheses sized 19, 21, or 23 mm had been implanted to replace aortic valves. MAIN OUTCOME MEASURES: Doppler echocardiography at rest and at peak exercise, between 12 and 47 months after surgery. RESULTS: All patients achieved a significant increase in heart rate, systolic blood pressure, and cardiac output with exercise. Transvalvar pressure fall, valve area, and left ventricular systolic and diastolic function indices also underwent significant changes with exercise. Reductions in peak and mean transvalvar pressure, at rest and at peak exercise, were greater in patients with small valves (p < 0.05). Valve areas and effective area index were greater in the patients with larger valves (p < 0.001). There were no significant differences between patients with mechanical and biological prostheses with regard to transvalvar pressure fall and valve areas at rest and at peak exercise. CONCLUSIONS: 19 mm and 21 mm aortic prostheses and bioprostheses continue to create significant obstruction, particularly with exercise.  (+info)

The use of a stentless porcine bioprosthesis to repair an ascending aortic aneurysm in combination with aortic valve regurgitation. (4/643)

Over the years, many surgical methods have evolved for the treatment of ascending aortic aneurysm in combination with aortic valve regurgitation; however, precise guidelines for optimal surgical techniques for varying presentations have not been defined. We describe the use of a stentless porcine bioprosthesis (Medtronic Freestyle) in a patient with an ascending aortic aneurysm and aortic regurgitation. We used the complete root replacement method, and anastomosed a Dacron graft (Hemashield) between the bioprosthetic valve and the native aorta to replace the distal part of the aneurysm.  (+info)

Hemodynamic and physical performance during maximal exercise in patients with an aortic bioprosthetic valve: comparison of stentless versus stented bioprostheses. (5/643)

OBJECTIVES: The objective of this study was to compare stentless bioprostheses with stented bioprostheses with regard to their hemodynamic behavior during exercise. BACKGROUND: Stentless aortic bioprostheses have better hemodynamic performances at rest than stented bioprostheses, but very few comparisons were performed during exercise. METHODS: Thirty-eight patients with normally functioning stentless (n = 19) or stented (n = 19) bioprostheses were submitted to a maximal ramp upright bicycle exercise test. Valve effective orifice area and mean transvalvular pressure gradient at rest and during peak exercise were successfully measured using Doppler echocardiography in 30 of the 38 patients. RESULTS: At peak exercise, the mean gradient increased significantly less in stentless than in stented bioprostheses (+5 +/- 3 vs. +12 +/- 8 mm Hg; p = 0.002) despite similar increases in mean flow rates (+137 +/- 58 vs. +125 +/- 65 ml/s; p = 0.58); valve area also increased but with no significant difference between groups. Despite this hemodynamic difference, exercise capacity was not significantly different, but left ventricular (LV) mass and function were closer to normal in stentless bioprostheses. Overall, there was a strong inverse relation between the mean gradient during peak exercise and the indexed valve area at rest (r = 0.90). CONCLUSIONS: Hemodynamics during exercise are better in stentless than stented bioprostheses due to the larger resting indexed valve area of stentless bioprostheses. This is associated with beneficial effects with regard to LV mass and function. The relation found between the resting indexed valve area and the gradient during exercise can be used to project the hemodynamic behavior of these bioprostheses at the time of operation. It should thus be useful to select the optimal prosthesis given the patient's body surface area and level of physical activity.  (+info)

Valve replacement for aortic stenosis in patients with poor left ventricular function: comparison of early changes with stented and stentless valves. (6/643)

BACKGROUND: Long-standing aortic stenosis causes significant left ventricular (LV) dysfunction, which may progress irreversibly. In many cases, LV function can be salvaged by aortic valve surgery, although debate exists regarding the best valve prosthesis to use. METHODS AND RESULTS: We studied 33 patients retrospectively who had significant aortic stenosis and impaired LV systolic function, as assessed by transthoracic Doppler echocardiography. Patients were assessed preoperatively and before discharge from the hospital. A total of 20 patients received a stentless (homograft or Toronto) valve, and 13, a stented valve. No patient had significant aortic regurgitation or other valvular disease. Preoperatively, fractional shortening was 18.8+/-5.5% in the stentless group and 18.6+/-3.8% in the stented group. Postoperatively, it was 25.6+/-6.9% (P<0.001 compared with baseline) and 17.0+/-2.8%, respectively (P<0.001 compared with stentless group). Fractional shortening improved because of a reduction in LV end-systolic and end-diastolic dimensions in the stentless group. Systolic long axis function at the LV free wall also recovered, with an increase in systolic excursion and both peak shortening and lengthening rates. No change was noted in mitral valve Doppler patterns. CONCLUSIONS: Patients who received a stentless valve demonstrated a significantly greater early improvement in LV systolic function compared with those who received a stented valve.  (+info)

Prospectively randomized evaluation of stentless versus conventional biological aortic valves: impact on early regression of left ventricular hypertrophy. (7/643)

BACKGROUND: The aim of this prospectively randomized study was to evaluate left ventricular hypertrophy and its regression after stentless versus conventional biological aortic valve replacement. METHODS AND RESULTS: From March 1996 through April 1998, 180 patients were prospectively selected; 106 patients received a stentless aortic valve (SAV), and 74 received a conventional stented bioprosthesis (CSB). Of these patients, 95% and 96%, respectively, had aortic stenosis. Their mean age was 72.3 and 74.8 years, and there were no significant differences in left ventricular function, preoperative pressure gradients, and NYHA functional status. Aortic annulus diameter indexes were comparable at 13.46 (SAV) versus 13.55 (CSB) mm (P=NS). Larger SAVs were implanted because of the oversizing technique. In-hospital mortality (n=3 and 1 for SAV and CSB) was not valve related. At follow-up, all patients were in NYHA class 1 or 2. Baseline end-diastolic left ventricular posterior wall thickness was 15.6 (SAV) and 14.8(CSB) mm (P=NS) and decreased to 11. 8 (SAV) and 13.2 (CSB) mm (P<0.05) at 6 months. Left ventricular mass index was 213 and 202 g/m(2) at baseline (P=NS), whereas after 6 months, it was 141 (SAV) and 170 (CSB) g/m(2) (P<0.05). CONCLUSIONS: Regression of left ventricular hypertrophy occurs in all patients after aortic valve replacement but is significantly enhanced after SAV implantation. This possibly is due to improved transvalvular hemodynamics.  (+info)

Mid-term comparative follow-up after aortic valve replacement with Carpentier-Edwards and Pericarbon pericardial prostheses. (8/643)

BACKGROUND: The first generation of pericardial valves had a high rate of premature deterioration. The aim of this study was to compare the outcome after aortic valve replacement with second generation pericardial prostheses (Pericarbon and Carpentier-Edwards). METHODS AND RESULTS: Between 1987 and 1994, 162 patients underwent aortic valve replacement with either a Pericarbon (n=81, 69+/-11 years) or a Carpentier-Edwards (n=81, 70+/-11 years) pericardial prosthesis. Mean follow-up was 4.4+/-2.7 years for Pericarbon and 4.8+/-2.4 years for Carpentier-Edwards valves (P=0. 27), giving a total follow-up of 745 patient-years. Thirty-day mortality and 5-year actuarial survival were, respectively, 6.2% and 63.2+/-5.7% in the Pericarbon group and 6.2% and 63.5+/-5.6% in the Carpentier-Edwards group. At 8 years, freedom from (and linearized rates per patient-year) thromboembolism, structural failure, and all valve-related events were, respectively, 91.8+/-3.6% (1.4%), 76. 9+/-8.7% (2.5%), and 58.4+/-9.3% (5.6%) in the Pericarbon group and 94.4+/-2.7% (1%), 100% (0%, P<0.01), and 88.8+/-3.7% (2%, P<0.05) in the Carpentier-Edwards group. There were 9 (11.1%) Pericarbon structural failures related predominantly to severe calcification and stenosis. The actual reoperation rate was 7.4% (1.6% per patient-year) in the Pericarbon group for fibrocalcific degeneration (n=3), periprosthetic leak (n=1), endocarditis (n=1), and aortic dissection (n=1). There was neither structural valve failure nor valve reoperation in the Carpentier-Edwards group. Echocardiographic review of 70 patients from 85 survivors (82.3%) found 4 additional Pericarbon valves with signs of early structural failure but no Carpentier-Edwards valve with such changes. CONCLUSIONS: Eight years after aortic valve replacement, Pericarbon pericardial prostheses compared unfavorably with Carpentier-Edwards pericardial prostheses, with a high incidence of structural valve failure and reoperation.  (+info)

Bioprosthesis has been increasingly implanted for the treatment of transvalvular disease across the world. A new Dafodil™ pericardial bioprosthesis (Meril Life Sciences Pvt. Ltd., India) recently approved by Conformité Européenne (CE) is a tri-leaflet, stented, bovine valve. The purpose of Dafodil-1 first-in-human trial was to evaluate clinical safety and performance (including hemodynamic parameters) of the Dafodil pericardial bioprosthesis in patients who underwent aortic or mitral valve replacement. This prospective, multicenter clinical trial enrolled 60 patients (Aortic: 30 patients; Mitral: 30 patients) from seven sites across India. Safety endpoints were early (≤30 days) and late (| 30 days) mortality and valve-related morbidity. The performance endpoints were hemodynamic performance, improvement in NYHA functional class, and change in the quality of life using SF-12v1 health survey. From July 2017 to July 2018, 60 patients underwent implantation of the Dafodil pericardial bioprosthesis.
TY - JOUR. T1 - Hemodynamic evaluation of 19-mm Carpentier-Edwards pericardial bioprosthesis in aortic position. AU - Takakura, Hiromitsu. AU - Sasaki, Tatsuumi. AU - Hashimoto, Kazuhiro. AU - Hachiya, Takashi. AU - Onoguchi, Katsuhisa. AU - Oshiumi, Motohiro. AU - Takeuchi, Shigeyuki. PY - 2001. Y1 - 2001. N2 - Background. The aortic Carpentier-Edwards pericardial bioprosthesis offers good long-term clinical outcomes with a low rate of structural deterioration. However, little in vivo hemodynamic data is available for this bioprosthesis. Methods. To determine the hemodynamic performance of the 19-mm Carpentier-Edwards pericardial valve, both cardiac catheterization and dobutamine stress echocardiography were electively performed in 10 patients. The mean age at the study was 71.6 ± 4.4 years and the mean body surface area was 1.39 ± 0.11 m2. The peak-to-peak gradient, instantaneous peak gradient, mean gradient, and valve orifice area were measured by standard cardiac catheterization. The ...
Transcatheter aortic valve implantation for failing surgical aortic bioprosthetic valve: from concept to clinical application and evaluation (part 2). JACC Cardiovasc Interv. 2011 Jul; 4(7):733-42 ...
We describe a case of a 76-year old male who presented with progressive dyspnoea. He underwent an aortic valve replacement with a Freedom SOLO bioprosthesis 6 years ago. Transthoracic echocardiography showed a moderate-to-severe leakage of the Freedom SOLO bioprosthesis. During surgical reintervention, a partial tear of the left coronary cusp was seen from the commissure of the right coronary cusp to its base. After radiographic and microscopic examination, no clear cause was found for the failure of this Freedom SOLO bioprosthesis. To our knowledge, this is the third failure of a Freedom SOLO bioprosthesis reported in the literature. When the long-term follow-up of the Freedom SOLO bioprosthesis is available, it has to be compared with other bioprosthesis for long-term durability. ...
TY - JOUR. T1 - Aortic Valve Bioprostheses. T2 - Leaflet Immobility and Valve Thrombosis. AU - Holmes, David. AU - Mack, Michael J.. PY - 2017/5/2. Y1 - 2017/5/2. N2 - Leaflet immobility and valve thrombosis have been reported with both transcatheter and surgical aortic valve bioprostheses. The relationships between these abnormalities and their incidence, time course, clinical significance, predisposing factors, optimal imaging modality, and current therapeutic options remain uncertain but are rapidly evolving. Four-dimensional computerized tomographic imaging has been determined to have the highest sensitivity in studies evaluating leaflet immobility and valve thrombosis. Echocardiography is also used during surveillance, but it appears to be less sensitive. The definitive diagnosis of valve thrombosis is based on a combination of diagnostic 4-dimensional computerized tomographic imaging findings, resolution of imaging abnormalities, and elevated transcatheter gradients with anticoagulation or ...
Title:Prevention of Bioprosthetic Heart Valve Calcification: Strategies and Outcomes. VOLUME: 21 ISSUE: 22. Author(s):L.P. Bre, R. McCarthy and W. Wang. Affiliation:Network of Excellence for Functional Biomaterials (NFB), National University of Ireland, Galway, IDA Business Park, Dangan, Galway, Ireland.. Keywords:Anticalcification, bioprosthesis, crosslinking, glutaraldehyde, heart valve replacement, mineralization.. Abstract:Despite the significant advances in cardiac surgery, heart valve replacement still faces a dilemma. While mechanical valves offer lifelong durability they also commit patients to anticoagulation treatment for the rest of their life. On the other hand, bioprosthetic valves have superior hemodynamic performance but durability of the bioprosthesis limits their use to the elderly, with early onset calcification being the primary cause of biomaterial breakdown. Considering that bioprosthetic valves are not reliant upon anticoagulation, there has been much focus on measures to ...
There has been a trend toward more frequent use of bioprosthetic valves, especially in the young generations, over the last decade.1,2 According to the Society of Thoracic Surgeons database, use of bioprosthetic valve increased from 44% in 1996 to 78% in 2006 in North America.1 Freedom from warfarin use and restrictions on diet and activities make bioprosthetic valves more attractive and popular, and multiple reports have shown that choosing a bioprosthetic valve does not decrease survival despite the increased rate of reoperation.3,4. Article see p 2012. The Mitroflow aortic prosthesis (Sorin Group Inc) is one of the most frequently used bioprostheses, with ,100 000 implanted worldwide.5 The bovine pericardium is mounted externally around the stent, which maximizes the flow relative to the stent size. The valve is placed in the supra-annular position compared with the intra-annular position in some of the other bioprostheses. These characteristics allow superior valve hemodynamics in the ...
Several studies have recognized the high prognostic relevance of achieving an optimal hemodynamic result after aortic valve replacement (1-3,13-16). The presence of severe PPM has been associated with lesser improvement in the functional capacity of the patients (13), lesser regression of LV hypertrophy (14), higher rates of cardiac failure (16), and higher rates of perioperative and long-term mortality (2,3,15,16) after SAVR. The Magna and Freestyle valves are among the most commonly used stented and stentless bioprostheses for SAVR, and the results of valve hemodynamic performance observed in the present study for these 2 types of bioprosthesis were consistent with those of previous studies (17-20), although the aortic annulus and bioprosthesis size were smaller in the present study. Previous studies have also reported that the hemodynamic performance of stentless bioprostheses is generally superior, and accordingly, the prevalence/severity of PPM is lower compared with stented bioprostheses ...
Calcification of glutaraldehyde-preserved bioprosthetic cardiac valves represents a serious clinical problem. Previous work from this laboratory has established the presence in clinical bioprosthetic valve calcifications of vitamin K-dependent calciu
Since the first implant in September 1982, the Medtronic Hancock® II has provided more than 20 years of excellent hemodynamic performance and durability. Design improvements over the past generations include: low profile, flexible stent, Supra-X™ supra-annular placement, T6 anti-calcification tissue treatment, modified fixation process, CINCH® advanced implant system and ULTRA™ minimized sewing ring. Valve sizing is a critical consideration in obtaining optimal hemodynamic performance. This is particular true in small aortic roots. A critical issue is the size of the prosthesis in relation to the patients annulus.. The objective of this clinical study is to evaluate, at six and twelve months, the hemodynamic performance of the HancockÒ Ultra™ bioprosthesis in the aortic position, to analyze the incidence of patient prosthesis mismatch, correlation of gradients, and to ascertain frequency at which a larger valve size is used vs. a patients debrided annulus diameter. ...
Health,...MINNEAPOLIS Nov. 24 /- ATS Medical Inc.(Nas... (Logo: a href http://www.newscom.com/cgi-bin/prnh/20040202/ATSI... The ATS 3f Aortic Bioprosthesis is the Companys first entry into ... The ATS 3f Aortic Bioprosthesis is the only tissue valve that pre...,ATS,Medical,Announces,First,Commercial,Implants,of,the,ATS,3f,Aortic,Bioprosthesis,in,the,United,States,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Between May 1st 1985 and December 31st 1992, 283 Carpentier-Edwards pericardial valves were implanted in 260 patients in the aortic (n = 196), mitral (n = 41) and both aortic and mitral (n = 23) positions at the Gasthuisberg University Hospital in Leuven, Belgium. Patients undergoing tricuspid valve replacement or mixed replacement with another type of prosthesis were excluded from this study. The mean age was 70 +/- 7 years, there were 121 males and 139 females. The mean follow up was 40.55 months, the total follow up experience 10543 months (878.6 patients years). Hospital mortality was 10.4%, and was not significantly related to the position of the valve: 17.3% +/- 7.88% (n = 23) for double valve replacement, 10.2% +/- 2.16% (n = 196) for aortic valve replacement and 7.3% +/- 4.06% (n = 41) for mitral valve replacement. Hospital mortality was 14.1% +/- 3.27% for those with and 7.48% +/- 2.5% for those without concomitant coronary surgery (p = NS). Survival at 92 months was 63% +/- 6% and was ...
A bioprosthetic heart valve comprising leaflets with free edges which do not impinge on adjacent leaflets when the leaflets are closed before being implanted and subject to body fluids and cardiac pressure cycles. Commissures supporting the leaflets have semi-permeable membranes which reduce the pressure load on the leaflets during implantation. In response to immersion in body fluids, the membranes become substantially impermeable. The leaflets can stretch in response to loads and hydration, so that the free edges mate shortly after implantation. First and second mechanisms for supporting leaflets to provide multiple effective spring constants. An inner frame supporting commissures of the valve is elastic, permitting the commissures to bend in toward the center of the prosthetic heart valve at very low loads. A relatively rigid annular support ring supports the elastic frame and provides the second spring constant mechanism. The leaflets have an uncoupled mating edge where the leaflet approach each
Transcatheter heart valve in valve implantation with Edwards SAPIEN bioprosthetic valve for different degenerated bioprosthetic valve positions (First Iranian ViV report with mid-term follow up) ...
A packaging system is disclosed for shipping a prosthetic tissue valve in a storage solution and preparing and loading of the bioprosthetic valve onto a catheter-based delivery system. The packaging system includes a fluid tight container filled with the storage solution attached to a delivery catheter, wherein the container surrounds the prosthetic tissue valve that is in a pre-loaded position on the delivery catheter during shipment and storage. The prosthetic tissue valve may include an attachment mechanism that attaches to the delivery catheter to properly position the tissue valve for loading within the delivery catheter. In another embodiment where the prosthetic tissue valve is not attached to the delivery catheter during shipment, the attachment mechanism may interact with the prosthetic tissue valve shipping container to prevent the bioprosthetic valve from moving during shipment.
Bioprosthetic valve thrombosis (BPVT) can occur several years after implantation but much earlier than degeneration, stress Sorin V. Pislaru, MD, PhD, and colleagues. The good news, they say, is that cases-once diagnosed-respond well to vitamin K antagonist (VKA) therapy.. The findings are being published in the December 1, 2015, issue of the Journal of the American College of Cardiology.. Raj R. Makkar, MD, of Cedars-Sinai Heart Institute (Los Angeles, CA), lead author of the NEJM paper, told TCTMD in a telephone interview: Clearly weve underappreciated the importance of leaflet thrombosis on structural valve failure, and in a subset of patients this may be the mechanism.. No prospective RCTs have tested the value of anticoagulation in patients with bioprosthetic valves, and studies on both surgical and transcatheter valves would be important, he noted.. Makkar said awareness of these issues is growing in the TAVR field. I think people are serious and people are interested. Everybody ...
TY - JOUR. T1 - Morphological comparison of mitral and aortic bioprostheses explanted from the same patient for primary tissue failure. AU - Pansini, S.. AU - Di Summa, M.. AU - Galloni, M.. AU - Gagliardotto, P.. AU - Parisi, F.. AU - Zattera, G.. AU - Punta, G.. AU - Girotto, M.. AU - Cesarani, F.. PY - 1996/6. Y1 - 1996/6. N2 - Host factors might influence the fate of tissue prostheses. We have analyzed the tissue failure phenomenon in mitral and aortic porcine bioprostheses explanted from the same patient so as to avoid the bias of host factors. The 50 bioprostheses of this study were explanted from 25 patients reoperated on because of malfunctioning due to primary tissue failure. Bioprostheses explanted were photographed, radiographed and observed in polarizing light. All lesions analyzed received a score on the basis of morphological criteria. No difference was observed in the occurrence of pannus, tears or cells infiltrates. Calcifications occurred more extensively in mitral position (p = ...
Price of a print issue €25.00. AIM: The use of synthetic mesh in transplant patients is still under debate. In this paper the authors report their preliminary experience on biological prosthesis for surgical treatment of incisional hernias in transplant patients. MATERIAL OF STUDY: Between 2009-2010, 10 patients with incisional hernia underwent surgery using a biological prosthesis (porcine dermis collagen). All patients were transplanted: 9 kidney transplants and 1 liver transplant. RESULTS: In all patients postoperative course was uneventful and were not observed complications related to surgery, kind of prosthesis or transplanted organs. At follow up, laparoplasty was associated with good functional outcome. DISCUSSION: Transplant patients are at risk for use of synthetic prostheses, as immunosuppressed. In our preliminary experience biological prostheses compared to synthetic ones showed a greater ability to integrate into tissues, to resist bacterial colonization and to reduce cytotoxic ...
The VIV procedure is technically demanding and should be reserved for highly experienced centers. Operators should be skilled in the handling of device malposition, retrieval techniques, and implantation of a second TAVR device, if needed. During screening, the Heart Team must have all of the information about and be familiar with the particular characteristics of the surgical bioprosthesis: the mode of degeneration and echocardiographic parameters (isolated paravalvular regurgitation should be excluded); valve size (most importantly, bioprosthesis internal diameter should be used for TAVR device and size selection; because of better hemodynamic results, CoreValve may be preferred in cases of small bioprosthesis with internal diameter ,20 mm); valve position (intra-annular versus supra-annular); valve type (stented versus stentless); the relation of the bioprosthetic valve to its radio-opaque markers; and the risk for coronary obstruction when VIV is performed inside that specific ...
The valve-in-valve concept is an emerging therapeutic option for patients with degenerative failure of previously implanted xenografts. Reoperation of degenerated bioprostheses has a high mortality risk that increases with the age and associated comorbidities of the patients. The transcatheter valve-in-valve implantation does not need resternotomy or cardiopulmonary bypass, potentially reducing the morbidity and mortality risk. However, unlike the transcatheter implants in native valves, in the valve-in-valve procedures, the leaflets and calcified annulus are replaced with the rigid annulus of the xenograft. This requires accurate sizing of the transcatheter valve, currently available in 2 sizes. Therefore, 3-dimensional imaging techniques, particularly multi-detector row computed tomography (MDCT), may provide a more exact sizing of the host xenograft ring. We report a mitral valve-in-valve procedure in a 79-year-old female patient with previous aortic and mitral valve replacement (a 21-mm and ...
TY - JOUR. T1 - Long-Term Outcomes of Anticoagulation for Bioprosthetic Valve Thrombosis. AU - Petrescu, Ioana. AU - Egbe, Alexander C.. AU - Ionescu, Filip. AU - Nkomo, Vuyisile T.. AU - Greason, Kevin L.. AU - Pislaru, Cristina. AU - Pellikka, Patricia A.. AU - Connolly, Heidi M.. AU - Pislaru, Sorin V.. PY - 2020/3/3. Y1 - 2020/3/3. N2 - Background: Early in the prevention and treatment of bioprosthetic valve thrombosis (BPVT), anticoagulation is effective, but the long-term outcome after BPVT is unknown. Objectives: The goal of this study was to assess the long-term outcomes of patients with BPVT treated with anticoagulation. Methods: This analysis was a matched cohort study of patients treated with warfarin for suspected BPVT at the Mayo Clinic between 1999 and 2017. Results: A total of 83 patients treated with warfarin for suspected BPVT (age 57 ± 18 years; 45 men [54%]) were matched to 166 control subjects; matching was performed according to age, sex, year of implantation, and ...
A new study has found that in patients with failed bioprosthetic aortic valves who underwent transcatheter valve-in-valve implantation, the survival rate was only 83 percent
Bioprosthetic valves are increasingly used in preference to mechanical valves in open SAVR, as lifelong oral anticoagulation is not required and its attendant complications can be avoided. A recent study has shown similar long-term survival rates in patients with bioprosthetic and mechanical valves. However, patients with bioprosthetic valves require reoperations due to their limited durability and expected degeneration;(12) those undergoing such reoperations face increased surgical risk due to their more advanced age (compared with their age during the index SAVR) during the redo surgery and scarring in the non-virgin chest. Consequently, valve-in-valve TAVI appears to be an attractive, minimally invasive method of replacing the degenerated surgical aortic bioprosthesis without the need for a reoperation. Several small case series and a global registry have shown that it is a feasible and viable option for patients at high risk.(5-9). In our initial Asian experience of valve-in-valve TAVI in ...
Fingerprint Dive into the research topics of Comparative performance of transcatheter aortic valve-in-valve implantation versus conventional surgical redo aortic valve replacement in patients with degenerated aortic valve bioprostheses: systematic review and meta-analysis. Together they form a unique fingerprint. ...
Methods and results Preoperative echocardiography and dobutamine stress echocardiography at 1 year postoperatively were undertaken in 106 patients (n=18-24 from each group). Stentless bioprostheses, whether porcine or bovine, displayed superior haemodynamics across nearly all echocardiographic parameters: lower gradients, larger effective orifice area, higher dimensionless severity index (DSI) and lower resistance, when compared with stented or mechanical prostheses. Comparing both stented designs, bovine tissue performed the worst at rest, but with stress, there was no difference. The stress performances of the stentless bioprostheses were similar to the mildly stenosed native aortic valve, whereas the performances of the stented and mechanical prostheses resembled that of native valves with mild-to-moderate stenoses. Haemodynamic differences, however, did not translate into differences in left ventricular mass reduction at 1 year.. ...
Sorin Group (Milan, Italy) has been awarded CE mark approval for the Solo Smart, a stentless aortic valve implant. Like its predecessor, the Freedom Solo v
CARDIOTHORACIC ANESTHESIOLOGY: Clinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Aortic Valves by Four-Dimensional Computed Tomography is organized by The Society of Thoracic Surgeons (STS).
Surgical Bailout Therapy after Implantation of a Medtronic CoreValve Bioprosthesis. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
We carefully read the recent paper by Hammond et al. (1) on the use of sutureless bioprosthetic valve for homograft failure in the setting of infective endocarditis (IE). This article is the latest demonstration that new sutureless and rapid deploymen
When facing heart valve replacement surgery, its important to understand the available options. Check out this blog post to learn more!
A biomaterial useful for bioprostheses such as bioprosthetic heart valves is provided in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further characterized by having anisotropic properties wherein the biological material has a greater stiffness in one direction and a greater elasticity in a cross direction. For instance, the biological material has an elastin content of about 30% by weight. In one embodiment, the biological material is vena cava tissue.
Results In patients with VHD, rivaroxaban was associated with more ICH and major bleeding than other NOACs, while edoxaban 30 mg was associated with least major bleeding. Data combining all NOACs showed a significant reduction in SSE, MI and ICH (0.70, [0.57 to 0.85; p,0.001]; 0.70 [0.50 to 0.99; p,0.002]; and 0.46 [0.24 to 0.86; p,0.01], respectively). Analysis of 280 patients with AF and a BPHV showed similar outcomes with NOACs and warfarin. ...
Disclosed is a controlled autolysis method for making biological tissue substantially acellular by exposing the biological material, prior to any fixation thereof, to at least one buffered solution having a pH in the range from about 5.0 to 8.0 and a temperature in the range from about 12 C. to 30 C. for a sufficient period of time to render at least one region of the biological material substantially acellular while substantially preserving the structural integrity and non-cellular structural components of the biological material. Also disclosed is a method of making a bioprosthetic heart valve using biological material that has been treated by controlled autolysis and a method of treating a mammal having a defective heart valve using a bioprosthetic heart valve made, in part, by controlled autolysis.
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Mayos structural heart team provides comprehensive care to patients who have previously undergone surgery to replace the mitral or tricuspid valve with a tissue bioprosthesis. Existing dysfunctional bioprosthetic valves can be
Brief summary: aortic bioprostheses. Indications: For use in patients whose aortic valvular disease warrants replacement of their natural or previously placed prosthetic valve.. Contraindications: Do not use if surgeon believes it would be contrary to the patients best interests.. Complications and side effects: Stenosis, regurgitation, endocarditis, hemolysis, thromboembolism, valve thrombosis, nonstructural dysfunction, structural valve deterioration, anemia, arrhythmia, hemorrhage, transient ischemic attack/stroke, congestive heart failure, myocardial infarction, angina, any of which could lead to reoperation, explantation, permanent disability, and death.. Warnings: Alternative therapies should be considered in the presence of conditions affecting calcium metabolism or when calcium containing chronic drug therapies are used, including children, adolescents, young adults, and patients on a high calcium diet or maintenance hemodialysis. Should be used with caution in the presence of severe ...
November 27, 2007 - St. Jude Medical Inc. announced FDA approval of its Epic Stented Tissue Valve with Linx AC Technology. The Epic Valve, which is identical in design to the companys Biocor Valve, also incorporates patented anti-calcification technology designed to protect against tissue mineralization, or hardening.. An estimated 100,000 Americans undergo heart valve replacement annually and the majority of them receive tissue valves. Valve durability is affected by both mechanical stress and tissue calcification. The Epic Valve is designed to address both issues to deliver long-term performance.. The Epic Valve sets a new standard for addressing tissue mineralization and potentially extending long-term valve durability, said Vibhu Kshettry, M.D., director of Cardiac Surgery at the Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, and a principal investigator in the Epic clinical study. Enhanced durability, combined with a design that facilitates the implant ...
The Bioprosthesis Valves market report provides a detailed analysis of global market size, regional and country-level market size, segmentation market growth, market share, competitive Landscape, sales analysis, impact of domestic and global market players, value chain optimization, trade regulations, recent developments, opportunities analysis, strategic market growth analysis, product launches, area marketplace expanding, and technological innovations.
OBJECTIVES: The aim of this study was to evaluate the hemodynamic performance of a sutureless bioprosthesis under high workload at mid-term follow-up. METHODS: Thirty-two patients who underwent isolated aortic valve replacement with a Perceval sutureless bioprosthesis with a minimum follow-up of 1 year were enrolled in this study. S size prosthesis was deployed in 10 patients (31.3%), M size in 9 (28.1%), L size in 8 (25%) and XL size in 5 (15.6%). Effective orifice area (EOA), EOA index (EOAi), and transvalvular gradients were assessed at rest and during dobutamine stress echocardiography (DSE) a median of 19 ...
Professional information on Medtronics Hancock® Bioprosthetic Valved Conduits for use in reconstructive procedures for the repair of congenital or acquired cardiac and great vessel malformations or pathology.
A system for treating a vascular condition includes a conduit having an inner wall and at least one locking member positioned within the inner wall of the conduit. The system also includes a stented valve positioned in contact with the locking member within the inner wall of the conduit. A method for treating a vascular condition includes inserting a conduit with a stented valve into a target region of a vessel, positioning a contact portion of the stented valve against a locking portion of the conduit and preventing migration of the stented valve within the conduit based on the positioning.
A system for treating a vascular condition includes a conduit having an inner wall and at least one locking member positioned within the inner wall of the conduit. The system also includes a stented valve positioned in contact with the locking member within the inner wall of the conduit. A method for treating a vascular condition includes inserting a conduit with a stented valve into a target region of a vessel, positioning a contact portion of the stented valve against a locking portion of the conduit and preventing migration of the stented valve within the conduit based on the positioning.
Diagnosis Code T82.223S information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
Continuous improvement in the mechanics, preservation and anticalcification treatment made bioprostheses the standard mode of valve replacement in the aging population. A novel Support System with large openings at the Commissural posts has been developed and the performance and durability of bioprostheses constructed went under evaluation. … Heart valve pulse duplicator. A heart valve pulse duplicator Vivitro SPS3891 (Vivitro Systems Inc., Victoria, BC Canada) was used to measure hemodynamic parameters. All tests were performed with the standard FDA waveform …. Go to the Article ...
Diagnosis Code T82.222S information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
Source: ISTAT 2001: At the beginning of 2011, there were 608,493 people residing in Genoa, of whom 47% were male and 53% were female. PubMed Central. PubMed Central. For the period before ICD-10 implementation (1970-2002) and when Istat data (2004-2005) are lacking, mesothelioma deaths were estimated through statistical models (logistic, Poisson). Cox, Dana C.; Edwards, Michael Todd. Utility of a point-of-care device for rapid determination of prothrombin time in trauma patients: a preliminary study. The opening lines of How the Grinch Stole Christmas! EFFECTS OF CYCLIC FLEXURAL FATIGUE ON PORCINE BIOPROSTHETIC HEART VALVE HETEROGRAFT BIOMATERIALS. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Per quanto riguarda la richiesta di uno studio epidemiologico descrittivo, la informo, sempre la Cimini scrive a me, che le cause di morte della popolazione di ogni comune ...
John Hancock, a leading international financial services company, used ON24 (NYSE: ONTF) digital experiences to drive new business and expand reach to a greater number of financial advisors. John Hancock engaged more than 1,500 partners on the ON24 platform to help them increase new business by 266%, with advisors achieving five times as many sales compared to those that didnt attend a virtual event. ON24 allows us to reach and engage our partners in new and compelling ways that are having a positive impact on John Hancock and our partners businesses, said Krystina Enquist, director of meetings and events at John Hancock. Our digital experiences are driving increased sales and securing more new clients and policyholders for our many financial advisors. John Hancock previously hosted face-to-face meetings with business partners to share industry updates, offer continuing education, or provide guidance on numerous topics such as market projections, election outcome ramifications, and ...
TY - JOUR. T1 - Bioprosthetic mitral valve thrombosis complicating antiphospholipid antibody syndrome, successfully treated with thrombolysis. AU - Chamsi-Pasha, Mohammed A.. AU - Alyousef, Tareq. AU - Sayyed, Samer H. PY - 2014/1/1. Y1 - 2014/1/1. N2 - The incidence of bioprosthetic valve thrombosis and related embolic complications is extremely rare, obviating the need for long-term anticoagulation. As a result, experience in the diagnosis and treatment of bioprosthetic valve thrombosis is fairly limited. We report the first case of antiphospholipid antibody syndrome presenting as bioprosthetic mitral valve thrombosis, 15 months after valve replacement, and successfully treated with thrombolytic therapy. (Echocardiography 2014;31:E278-E281).. AB - The incidence of bioprosthetic valve thrombosis and related embolic complications is extremely rare, obviating the need for long-term anticoagulation. As a result, experience in the diagnosis and treatment of bioprosthetic valve thrombosis is fairly ...
TY - JOUR. T1 - Detection, localization, and quantitation of bioprosthetic mitral valve regurgitation. An in vitro two-dimensional color-Doppler flow-mapping study. AU - Vandenberg, B. F.. AU - Dellsperger, K. C.. AU - Chandran, K. B.. AU - Kerber, R. E.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 1988. Y1 - 1988. N2 - The usefulness of two-dimensional color-Doppler flow-imaging (2D Doppler) in the detection, localization, and quantitation of bioprosthetic mitral valve regurgitation is uncertain. Mitral bioprostheses, before and after the creation of transvalvular (n = 33), paravalvular (n = 17), or combined (n = 23) defects, were mounted in a pulsed duplication system (flow rates, 2.5-6.5 l/min; pulse rate, 70 beats/min). An Aloka 880 2D Doppler system (Japan) was used to image the regurgitant jets in the simulated left atrial chamber, analogous to images obtained with transesophageal echocardiography. Jet area was corrected to an estimate of stroke volume: 2D ...
The perfect heart valve substitute has not yet been developed and matching the patient to existing options to optimize survival and reduce valve-related complications remains challenging. The choices for aortic valve replacement (AVR) are mechanical valves, bioprosthetic valves, and biological valves such as aortic valve homograft and the Ross procedure (pulmonary autograft). The latter is a complex operation because it transfers the patients own pulmonary valve into the aortic position and uses a biological valve to replace the pulmonary valve, transforming a single-valve disease into a 2-valve disease. These considerations are not important to most North American patients who undergo AVR because they are older and the durability of bioprosthetic valves in this age group is excellent (1,2). The risk of bioprosthetic valve failure 20 years after AVR is ,10% in patients 70 years of age and older (1,2). A report based on the Society of Thoracic Surgeons Database from January 1997 to December 2006 ...
The Edwards SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve system is indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be appropriate for the transcatheter heart valve replacement therapy.. The Edwards SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve system is indicated for patients with symptomatic heart disease due to failing (stenosed, insufficient, or combined) of a surgical or transcatheter bioprosthetic aortic valve or surgical bioprosthetic mitral valve who are judged by a heart team, including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 8% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).. Contraindications (Who should not use): ...
No survival difference was observed between use of mechanical and bioprosthetic mitral valves in patients aged 50-69 years matched by propensity score (actuarial 15-year survival 57.5% [95% confidence interval (CI) 50.5-64.4%] vs. 59.9% [95% CI 54.8-65.0%], hazard ratio [HR] 0.95 [95% CI 0.79-1.15]), or in a subgroup analysis of age by decade. Among patients matched by propensity score, mechanical versus bioprosthetic mitral valve replacement was associated with higher 15-year incidence of stroke (14.0% [95% CI 9.5-18.6%] vs. 6.8% [95% CI 4.5-8.8%], HR 1.62 [95% CI 1.10-2.39]) and bleeding events (14.9% [95% CI 11.0-18.8%] vs. 9.0% [95% CI 6.4-11.5%], HR 1.50 [95% CI 1.05-2.16]), but a lower incidence of reoperation (5.0% [95% CI 3.1-6.9%] vs. 11.1% [95% CI 7.6-14.6%], HR 0.59 [95% CI 0.37-0.94]).. ...
Subclinical leaflet thrombosis occurred frequently in bioprosthetic aortic valves, more commonly in transcatheter than in surgical valves. Anticoagulation (both NOACs and warfarin), but not dual antiplatelet therapy, was effective in prevention or treatment of subclinical leaflet thrombosis. Subclinical leaflet thrombosis was associated with increased rates of TIAs and strokes or TIAs. Despite excellent outcomes after TAVR with the new-generation valves, prevention and treatment of subclinical leaflet thrombosis might offer a potential opportunity for further improvement in valve haemodynamics and clinical outcomes.. ...
A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.
PhD Student Position in Mechanisms of Laminar-Turbulent Transition Past Bioprosthetic Aortic Valves The ARTORG Center for Biomedical Engineering Research is th
LivaNova PLC (NASDAQ:LIVN) a market-leading medical technology and innovation company, today announced that the advanced Perceval® Plus sutureless surgical aortic heart valve is now available for commercial release in Europe, having successfully completed a one-year limited launch with initial real-world clinical data gathering. Perceval Plus is positioned to become an essential component to any comprehensive heart program. Building on the clinically proven experience with Perceval®, this next-generation valve facilitates minimally invasive cardiac surgery (MICS) and makes sutureless aortic valve replacement available to a wide patient population. Key innovations with Perceval Plus include the anticalcification treatment, FREE, for valve durability, along with design changes intended to improve patient outcomes.
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Betsy Evans of Leeds General Infirmary in the United Kingdom presents a discussion on TAVI and surgery for prosthetic valve failure. She discusses the background of biological valve implant rate, rate of TAVI, and structural valve deterioration and treatment options. She focuses on two treatment techniques: redo AVR surgery and the TAVI valve-in-valve procedure.. ...
0067] In the embodiments described above relative to FIGS. 7 and 8, the tubular valve segments of stented valves of the invention have a ring of pericardial material that is thicker at one or both of its ends where the material is rolled or folded back on itself. This rolled-back material can overlap or cover the edge of the stent, such as to cover the edge of the stent wires, thereby making the edge or edges of the stented valve smoother. Alternatively, the material may be rolled or folded back in such a way that it does not cover the edge of the stent. For example, a folded portion of material can be positioned so that it is adjacent to an end of a stent and/or the folded portion of material can be positioned to face the interior opening or portion of the stent. In any case, the extra thickness of the material can be beneficial to prevent the stented valve from leaking around its perimeter when implanted in a patient. That is, the rolled or folded areas can help to stabilize the stented valve ...
The Edwards SAPIEN™ THV is a biological heart valve manufactured with treated bovine pericardial tissue that is mounted into a balloon expandable stainless steel open cell stent. The Edwards SAPIEN™ THV is available in two sizes (23 and 26mm) and is designed for transcatheter implantation in patients with regurgitant pulmonary valved conduit with or without stenosis. This device is commercially available and is used according the current IFU ...
For aortic root replacement in annuloaortic ectasia (AAE), an artificial prosthesis is commonly sutured to the aortic annulus (hemodynamic ventriculoaortic junction). We consecutively had 6 cases of aortic root replacement using anatomic ventriculoaortic junction suture. This anatomic ventriculoaortic junction suture is a simplified and practical method for aortic root replacement in the same way as using stentless bioprostheses or homografts ...
For the foreseeable future, bioprosthetic heart valves (BHV) fabricated from xenograft biomaterials will remain the dominant replacement prosthetic valve design...
Since the introduction of the sutureless Perceval® (Sorin Group, Saluggia, Italy) in Europe after CE mark in 2012, the sutureless approach is becoming more and more popular. Sutureless implantation in general is easy, fast and safe, but bears several potential pitfalls. This might result in inferior functional results affecting also clinical outcomes. In our center, more than 300 implant procedures have been performed up to date by mainly two senior surgeons. The technique is in the process of spreading to all surgeons performing aortic valve procedures. Proctored activities are completed at our and other institutions, and wetlab activities are conducted in collaboration with the manufacturers research and development laboratory. This article was written to give a step-by-step advice for surgeons who want to start a sutureless program or even have made limited experience with this approach wanting to reconfirm their technique. The focus is kept on surgical aspects regarding indication, ...
In terms of complications, Chhatriwalla said concerns have been raised about injuring the aorta or rupturing the annulus, though so far these have not been seen. Its also possible that BVF might increase the risk of thromboembolic events, though it might be hard to tease out the mechanism by which they occur, he said.. But there are ways to mitigate risks, Chhatriwalla stressed, such as by timing BVF differently.. Some operators favor doing BVF ahead of TAVR, he said. The thought behind this is that the size of the new TAVR valve is selected with the knowledge of whether or not the bioprosthetic valve can be fractured in the first place. So you fracture the valve first, you have success, and then put in maybe a larger-sized [TAVR] valve as a result, he explained.. But he and others at Saint Lukes prefer doing it after the TAVR device is implanted, Chhatriwalla added. Our mindset [is] were going to put in the valve size thats warranted, and were going to check the hemodynamics. Then if ...
The Carpentier-Edwards Bioprosthetic Valved Conduit (Model 4300) is made from a porcine (pig) aortic valve that has been preserved and mounted on a flexible frame. The flexible frame is composed of a corrosion resistant cobalt chromium metal alloy, silicone rubber, and is covered with polytetrafluoroethylene (PTFE) cloth. The valve is then mounted in a polyester tube. This device can be used to create an extra-cardiac pathway for blood flow in the pulmonic position. This conduit was introduced in the 1970s. ...
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AIM: Postoperative renal dysfunction after aortic valve replacement is a serious complication. To minimize its occurrence, risk factors have to be identified, and if possible eliminated. METHODS: Of 1000 consecutive patients, who underwent AVR, a file study was performed chi(2)nd logistic regression analysis were performed to study the effect of 24 preoperative, 7 peroperative and 7 postoperative factors on the occurrence of 30-day postoperative worsening of renal function. RESULTS: Fifty-three patients had a 30-day postoperative decrease of renal function. Nine of these patients died, which is significantly more than the mortality without this complication ( ...
Fatigue and Biodegradation in Engineered Tissue Devices: At present, about half of all heart valve replacements incorporate tissue-derived components: either transplanted human valves or so-called bioprostheses incorporating chemically-treated porcine or bovine tissues. While tissue valves offer more physiological blood flow and freedom for the patient from significant anti-clotting drugs, these valves typically fail in under 15 years. It has been estimated that more than 90% of all failed tissue valves show tears and perforations in the tissue leaflets; moreover, there is strong pathological evidence that host inflammatory cells are present at the margins of such damage. We are using a unique combination of mechanical fatigue simulation, proteolytic enzymes, and macrophage culture to look at the mechanisms by which engineered tissue valves fail. Weve shown a synergy between fatigue damage to collagen bundles and enzymatic cleavage (that is, the two acting together are more damaging than the ...
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Turkeys Istanbul International Jazz Festival has landed a pair of firsts - Paul Simon will make his first appearance in the country when he closes the event next month (Jul11) and Herbie Hancock will debut his Tribute To Miles show.The...
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Much has changed in the 21 years since Donna Zirkles physician found a lump during her annual breast exam.. The diagnostic mammogram that followed came back negative. Fortunately, Donnas doctor didnt stop there.. Bless my doctor, Donna said. She called me back and said, Donna, I know theres a lump there. Would you please go get an ultrasound? I actually thought about not doing that, but I trusted her. So, I went for the ultrasound, and I saw it on the screen-a little bitty thing.. Donna is one of a small number of patients - fewer than 10% - who receive a false negative from a mammogram. Her family physician sent her to see Cam Gabrielsen, then the breast surgeon at Hancock Health. Even Dr. Gabrielsen had his doubts about whether the 1.3cm tumor was cancerous.. I had a lumpectomy, Donna said. I hadnt signed off for a mastectomy, because they didnt think it was going to be cancer.. It was. And, three weeks later, she ended up having the mastectomy.. It turns out Donnas cancer was ...
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Dr. Michael Carter, MD is a Orthopedic Sports Medicine Surgery Specialist in Hancock, MI. He is affiliated with UP Health System - Portage. He is accepting new patients. Be sure to call ahead with Dr. Carter to book an appointment.
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Vanderbilt-Ingram Cancer Center and the Vanderbilt Institute of Chemical Biology developed out of the work of the Hancock Lab to merit national acclaim for cancer care and translational research that moves discovery from the lab to benefit patients. Today Vanderbilt-Ingram discoveries in cancer genetics are saving lives through precision cancer medicine that precisely targets therapy based on tumor characteristics for patients with melanoma and cancers of the lung, colon and breast. More potent cancer medicines are on the horizon as Vanderbilt-Ingram researchers identify promising candidates by designing novel molecules that effectively inhibit notoriously undruggable mutations found commonly in many cancers and drug-resistant tumors. This research could ultimately lead to treatment for many different types of cancer.. These groundbreaking innovations testify to the wonderful impact achieved by a remarkable family and friends working closely with Vanderbilt scientists. Their collective ...
IN THE UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF ALABAMA NORTHERN DIVISION DAVID HANCOCK, Plaintiff, v. JAMES HOOD, et al., Defendants. ) ) ) ) ) ) ) ) ) CIVIL ACTION 2:09-00026-KD-N JUDGMENT In accordance with the Order entered this date, it is ORDERED, ADJUDGED and DECREED that plaintiffs federal claims are DISMISSED with prejudice and that supplemental jurisdiction over the state-law claim under the Alabama Medical Liabilities Act, Ala. Code 6-5-484 (1975) asserted in Count Five of the Third Amended Complaint is hereby DECLINED and Count Five is DISMISSED without prejudice. Thus, it is ORDERED, ADJUDGED and DECREED that this action is DISMISSED in its entirety. DONE and ORDERED this 18th day of February, 2010. s/ Kristi K. DuBose KRISTI K. DuBOSE UNITED STATES DISTRICT JUDGE ...
278 ALLAN HANCOCK PACIFIC EXPEDITIONS VOL. 3 D. 138, dredged in 30 m., south of Tiburon Island, near Turners Island, Jan.; D. 347, in 22 m., off Punta Penasco, Feb. This species is distinct from Halymenia abyssicola of this paper in its thinner fronds (70-130 ft), outer cortex of only one or two layers of small cells, and absence of a thick surface jelly. Halymenia ? abyssicola sp. nov. Frondes planae membranaceae, minime 8 cm. latae, 300 [i crassae, marginibus integris, atro-roseae; glutino superficial! 25-35 p, crasso; corticibus stratis paucis cellularum minutarum dense aggregatarum, 5-7 u, diam. compositis; subcorticibus cellulis majoribus compositis; in medulla filamentis laxe intricatis et crabro con- junctiones stellae-formantes ostendentibus; (frondibus fructuosis nondum visis). Fronds plane, membranous, basal parts unknown, at least 8 cm. broad, with an entire margin, 300 ft thick, deep rose colored; cross section showing a thick surface jelly 25-35 ft thick, a cortical tissue of a few ...
I saw this piece by journalist and former Cameron-Levita speechwriter Ian Birrell, sometimes seen on the TV newspaper reviews: https://inews.co.uk/opinion/one-nation-toryism-has-died-a-brutal-death/ Ian Birrells view of Matt Hancock It would be a brave person who picked out the politician that has most debased themselves since the Brexit debacle exploded. But among the favourites in this crowded field…
E William Hancock is on CAP Network. CAP Network is a virtual workspace, to support collaboration among faculty, graduate students, postdocs and staff.
He was in Washington D.C. and inaugurated as Americas first president in 1789 when the Hancock Inn opened its doors. This room with a double bed and an inviting window seat alcove, overlooking the backyard, is a cozy retreat for a couple or single traveler. It is a perfect space for those who know how to travel light. There is a full bath with shower/tub combination.. ...
Five students from Allan Hancock College will travel to Louisville, Ky., to compete in the SkillsUSA National Championships, which aim to recognize st...
Corporate actions such as M&As come with multiple implications for your retirement plans. Let John Hancock can help you plan for the coming changes.
Buy Billy Hancock - Out of the Darkness [CD] at DeepDiscount.com. Music: Folk: 791022261127. Guaranteed Lowest Price. Free Shipping on Orders over $25!
Herbie Hancock  70th birthday bash  Carnegie Hall Bill Cosby  saxophonist Joe Lovano  trumpeter Terence Blanchard  saxophonist Wayne Shorter Miles Davis\\ 1960s quintet...
2001). "Midterm evaluation of the Tissuemed (Aspire) porcine bioprosthesis: 493 patients, 506 bioprostheses". The Annals of ... 2003). "Ten year experience with Aspire (Tissuemed) porcine bioprosthesis: single centre experience". Cardiovascular Surgery. ...
In this category we find examples such as animal tissue prostheses (xenogeneic bioprosthesis). Xenogeneic heart valves are of ... "In vitro testing of bioprostheses: influence of mechanical stresses and lipids on calcification". The Annals of Thoracic ...
Great damage can be inflicted on a bioprosthesis at the time of its implantation. One of the not so rare causes is allowing the ... Watanabe describes a case of an Ionescu-Shiley bioprosthesis which functioned 24years in the mitral position of a patient. The ... Macro and microscopic pathology studies of failed porcine bioprostheses by Schoen and Cohn showed in detail the process of ... Concerning the surgeon: Correct rinsing of the bioprosthesis prior to implantation, maintaining the moistness of the valve ...
Tricuspid valve replacement with either a mechanical valve or a bioprosthesis may be indicated depending on the patient. ... Mechanical prostheses can cause thromboembolic phenomena, while bioprostheses may degenerate with use. Some evidence suggests ...
"Primary safety and effectiveness feasibility study after surgical aortic valve replacement with a new generation bioprosthesis ...
Sef, D; Krajnc, M; Klokocovnik, T (February 2021). "Minimally invasive aortic valve replacement with sutureless bioprosthesis ...
"Tropheryma whipplei Infection of an acellular porcine heart valve bioprosthesis in a patient who did not have intestinal ...
... surgery is the replacement of one or more of the heart valves with either an artificial heart valve or a bioprosthesis ( ...
... bioprosthesis MeSH E07.695.110 - blood vessel prosthesis MeSH E07.695.120 - bone nails MeSH E07.695.125 - bone plates MeSH ...
... and developed and implanted the first ASEAN bioprosthesis, the PHCA porcine valve.[citation needed] In 2014, the Philippine ...
Valve-in-valve vs Reoperative Surgical Aortic Valve Replacement in Patients With Failed Aortic Bioprosthesis: Insight from ...
Carpentier-Edwards Pericardial Bioprosthesis.' This valve is reported to perform better than its predecessor, the original ...
Aortic Root Bioprosthesis for the replacement of malfunctioning native or prosthetic aortic valves with the option of aortic ... Freestyle Aortic Root Bioprosthesis. Every aspect of the Freestyle® bioprosthesis is meant to closely emulate the native aortic ... Why Choose the Freestyle Aortic Root Bioprosthesis?. The Freestyle® valve is a stentless bioprosthesis with 12 years of long- ... Prestyled Freestyle Bioprosthesis - Tailored for Your Convenience. The stentless Prestyled Freestyle™ bioprosthesis is ...
CoreValve VIVA Study Evaluation of the Clinical Outcomes of CoreValve in Degenerative Surgical Aortic Bioprosthesis.. The ... The bioprosthesis is manufactured by suturing valve leaflets and a skirt from a single layer of porcine pericardium into a tri- ... The bioprosthesis is processed with alpha-amino oleic acid (AOA™), which is a compound derived from oleic acid, a naturally ... Patient with prior endocarditis on failed bioprosthesis. *Patient has other medical illness associated with a limited life ...
We present a case of a 66-year-old man after the mini-Bentall procedure with severe dysfunction of the aortic bioprosthesis ( ... and cerebral protection in a patient with severe dysfunction of the aortic bioprosthesis. Aleksandra Gąsecka ... ViV TAVR is associated both with a higher stroke risk due to biodebris released from the degenerated bioprosthesis and ... and cerebral protection in a patient with severe dysfunction of the aortic bioprosthesis. Advances in Interventional Cardiology ...
Transcatheter Aortic Valve Replacement using an Evolut PRO Bioprosthesis in Low Risk Patients with Aortic Stenosis Presenter: ... Transcatheter Aortic Valve Replacement with Self-Expandable Supra Annular Valves for Failed Surgical Bioprostheses: Insights ...
Aortic valve replacement with a conventional stented bioprosthesis versus sutureless bioprosthesis: A study of 763 patients. ... Aortic valve replacement with a conventional stented bioprosthesis versus sutureless bioprosthesis: A study of 763 patients. ... Aortic valve replacement with a conventional stented bioprosthesis versus sutureless bioprosthesis : A study of 763 patients. ... Aortic valve replacement with a conventional stented bioprosthesis versus sutureless bioprosthesis : A study of 763 patients. ...
Bioprostheses frequently become calcified and stenosed, especially when implanted in younger patients. The general ... Balloon valvuloplasty of stenosed Carpentier-Edwards bioprosthesis at pulmonary position.. Authors: Oomman, Abraham. ... We report a case where balloon dilation of the stenosed bioprosthesis at pulmonary position was successfully performed with ... Oomman A, Ramachandran P, Subramanyan K. Balloon valvuloplasty of stenosed Carpentier-Edwards bioprosthesis at pulmonary ...
Cardiac bioprosthesis and vascular prosthesis. D + H, 12. No. No. 3. 51/M. Yes. Cardiac bioprosthesis and TOF. D 12 + H 4 ( ...
... ... NEW METHOD FOR HEART VALVE BIOPROSTHESES ANTICALCIFICATION TREATMENT 28.10.2007 10:23. Download File ... Home \ Healthcare Professionals \ Articles \ Cardiac Surgery \ NEW METHOD FOR HEART VALVE BIOPROSTHESES ANTICALCIFICATION ...
Eight of these underwent tricuspid valve replacement surgery with bioprostheses (2 also had open pulmonic valvuloplasty). ...
Thirty-day results of the SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) registry: a European registry of transcatheter ... Impact of patient-prosthesis mismatch on exercise capacity in patients after bioprosthesis aortic valve replacement. Heart. May ... Prosthesis-patient mismatch after transcatheter aortic valve implantation with the Medtronic-CoreValve bioprosthesis. Eur Heart ...
Dr Brewer: What about novel oral anticoagulants for bioprosthesis? Do these agents have any role? ...
The Freestyle aortic bioprosthesis is a new type of aortic xenograft, and experience is limited. We therefore determined the ... Doppler values were evaluated for the Freestyle stentless porcine bioprostheses in the aortic root. Gradients appear to be ... Three hundred thirty-nine consecutive patients with a Freestyle aortic bioprosthesis underwent an echocardiographic and Doppler ... of this study was to determine normal Doppler and 2-dimensional characteristics of the Freestyle stentless aortic bioprosthesis ...
In the preparation of grafts and bioprostheses. *In various clinical applications. NIOSH recommends that employers use ...
Re-endothelialization of biological tissue-engineered conduits and scaffold for its potential use in bioprosthesis ... Re-endothelialization of biological tissue-engineered conduits and scaffold for its potential use in bioprosthesis. OA Tissue ...
Categories: Bioprosthesis Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 7 ...
Evaluation of Hemodynamic Performance of Aortic Valve Bioprostheses in a Model of Oversizing. In: Annals of Thoracic Surgery. ... Evaluation of Hemodynamic Performance of Aortic Valve Bioprostheses in a Model of Oversizing. Annals of Thoracic Surgery. 2017 ... Evaluation of Hemodynamic Performance of Aortic Valve Bioprostheses in a Model of Oversizing. / Cleveland, John D.; Bowdish, ... Dive into the research topics of Evaluation of Hemodynamic Performance of Aortic Valve Bioprostheses in a Model of Oversizing ...
S.A.V. Bioprosthesis. Edwards Lifesciences LLC Irvine, CA 92614. Approval for the labeling change based on the post-approval ...
Stentless Bioprostheses Market By Type (Xenograft, Allograft and Autograft), By Applicatio... Price - $5450 Dec 22 ...
The authors sewed in a bioprosthesis. The patient also had ischemic heart disease involving left anterior descending arteries, ... A postoperative echocardiogram was done, which demonstrated a competent aortic bioprosthesis with no evidence of leak. ...
Bioprosthesis Internal Orifice Diameter*. 18-21 mm. 21-23.5 mm. Valve-in-valve indications for 23 mm and 26 mm SAPIEN XT valves ... The internal orifice diameter of the surgical bioprosthesis must be determined prior to the procedure for appropriate ...
Copyright © 2022 by Shellock R & D Services, Inc. and Frank G. Shellock, Ph.D. All rights reserved.. ...
At 61 years of age, he developed severe symptomatic tricuspid regurgitation due to bioprosthesis degeneration and was judged at ... with surgical implantation of mechanical aortic and mitral prostheses at the age of 30 years and tricuspid bioprosthesis at the ...
Avalus™ Bioprosthesis is the Next Generation stented pericardial aortic valve, developed by Medtronic to advance cardiac ... Meet your patients need for minimally invasive procedures: choose Avalus™ Bioprosthesis and COR-KNOT® for SMART AVR.. 5 ... Medtronic offers the full spectrum to treat aortic stenosis patients with our products Evolut™ TAVI and Avalus™ Bioprosthesis. ... Watch the real case implantation experience of Avalus™ Bioprosthesis by Prof. Michael G. Moront. ...
Evans, J. L., Ng, K. H., Vonesh, M. J., Kramer, B. L., Meyers, S. N., Mills, T. A., Kane, B. J., Aldrich, W. N., Jang, Y. T., Yock, P. G., Rold, M. D., Roth, S. I. & McPherson, D. D., Feb 1994, In: Circulation. 89, 2, p. 712-717 6 p.. Research output: Contribution to journal › Article › peer-review ...
... such as those with degenerative surgical bioprosthesis.2 While the procedure is successful in most cases, some life-threatening ... An echocardiogram showed a mild stenosis of the bioprosthesis (peak gradient: 35mmHg; mean gradient: 15mmHg; aortic valve area ... in the context of TAVI in patients with prior surgical bioprosthesis ("valve-in-valve" - ViV-TAVI).2 ... Taking into consideration these high-risk anatomical characteristics and the presence of a previous stentless bioprosthesis, we ...
The performance of the Hancock modified orifice (MO) bioprosthesis is comparable with that of other bioprostheses despite its ... Twenty-year clinical experience with porcine bioprostheses 32nd Annual Meeting of the Society-of-Thoracic-Surgeons Fann, J. I ... At present, bioprostheses for the diseased aortic valve include stented porcine and pericardial valves, stentless porcine ... Younger age and use of a bioprosthesis were predictors of late reoperation. Type of procedure (GV versus CVG) was not a ...
Dynamic evaluation of the 21mm Medtronic Intact Aortic Bioprosthesis by Dobutamine Echocardiography. Kadir, I., Izzat, MB., ...
Twenty year comparison of a Bjork-Shiley mechanical heart valve with porcine bioprostheses. H Oxenham et al., Heart, 2003 ...
  • Unaccelerated squamosomastoid, «cialis buy online canada» much southwestwardly global, cialis insurance subinferred self-focusing bioprosthesis. (drjaliman.com)
  • Doppler values were evaluated for the Freestyle stentless porcine bioprostheses in the aortic root. (ox.ac.uk)
  • The Freestyle ® valve is a stentless bioprosthesis with 12 years of long-term data 1 that mimics human physiology to create physiologic flow resulting in superior patient outcomes. (medtronic.com)
  • Echocardiographic parameters of the freestyle stentless bioprosthesis in aortic position: the European experience. (ox.ac.uk)
  • Avalus™ Bioprosthesis is the Next Generation stented pericardial aortic valve, developed by Medtronic to advance cardiac surgical care. (medtronic.com)
  • by International Symposium on Cardiac Bioprostheses (3rd: 1985 : London, U.K. (who.int)
  • Background The risk of patient-prosthesis mismatch drives most surgeons to select the largest bioprosthesis possible during aortic valve replacement, but interactions between the native aortic annulus and valve prosthesis remain poorly defined. (elsevier.com)
  • The risk of systemic embolisation for the various valve types are approximately 4%/year for mitral prostheses (either mechanical prosthesis in a patient on anticoagulants or bioprosthesis in a patient not on anticoagulants) and approximately 2%/year for aortic prostheses (mechanical prosthesis with anticoagulants or bioprosthesis without anticoagulants). (ukdmc.org)
  • A "dyslipidemic/dysmetabolic profile characterized by elevated plasma Lp-PLA2, PCSK9, and HOMA index are associated with increased risk of HVD [hemodynamic valve deterioration] at mid-term follow-up in patients with aortic bioprostheses," Pibarot's group concluded. (medpagetoday.com)
  • Eight of these underwent tricuspid valve replacement surgery with bioprostheses (2 also had open pulmonic valvuloplasty). (nih.gov)
  • Three hundred thirty-nine consecutive patients with a Freestyle aortic bioprosthesis underwent an echocardiographic and Doppler examination according to a common protocol. (ox.ac.uk)
  • The Freestyle bioprosthesis, offered in a full-root configuration, is designed to offer the surgeon unmatched surgical versatility in implant options and the flexibility to meet diverse patient clinical indications. (medtronic.com)
  • CoreValve VIVA Study Evaluation of the Clinical Outcomes of CoreValve in Degenerative Surgical Aortic Bioprosthesis. (clinicaltrials.gov)
  • To collect real-world (post-approval use) data regarding the clinical utility and performance of the Medtronic CoreValve® System for TAVI in patients with failing surgical aortic bioprosthesis who are at high risk for redo surgery. (clinicaltrials.gov)
  • Subjects will be screened from symptomatic high risk adult patients candidates for an intervention on degenerative surgical aortic bioprosthesis. (clinicaltrials.gov)
  • The internal orifice diameter of the surgical bioprosthesis must be determined prior to the procedure for appropriate transcatheter heart valve sizing. (edwards.com)
  • A man with severe rheumatic trivalvular disease was treated with surgical implantation of mechanical aortic and mitral prostheses at the age of 30 years and tricuspid bioprosthesis at the age of 50 years. (ajconline.org)
  • At 61 years of age, he developed severe symptomatic tricuspid regurgitation due to bioprosthesis degeneration and was judged at very high risk for a third surgical approach. (ajconline.org)
  • ViV TAVR is associated both with a higher stroke risk due to biodebris released from the degenerated bioprosthesis and increased risk of coronary occlusion, especially in patients with a short distance between the bioprosthesis and coronary ostia [2]. (termedia.pl)
  • Bioprostheses frequently become calcified and stenosed, especially when implanted in younger patients. (who.int)
  • Patients with sever symptomatic AS at intermediate operative risk were randomized 1:1 to TAVR with supra-annular self-expanding bioprosthesis or surgery, from June 2012 to June 2016 in 87 centers in Canada, Europe, or the United States. (physiciansweekly.com)
  • Conclusions Bioprosthetic oversizing impairs hemodynamic performance of aortic valve bioprostheses. (elsevier.com)
  • There are two types of prosthetic valves: bioprostheses (animal tissue valve) and mechanical valves (made from mechanical parts) At The Nancy and Bill Thompson Heart Valve Center, both types of valves are available. (hoag.org)
  • Every aspect of the Freestyle ® bioprosthesis is meant to closely emulate the native aortic valve and offer comparable benefits. (medtronic.com)
  • This bioprosthesis is similar to the healthy native aortic valve, which preserves the aortic root physiology. (medicaldevice-network.com)
  • 4. Degeneration of Bioprostheses. (ukdmc.org)
  • Why Choose the Freestyle Aortic Root Bioprosthesis? (medtronic.com)
  • The unique full root design of the Freestyle bioprosthesis offers multiple implant options to address valve and root pathologies. (medtronic.com)
  • The absence of a stent and sewing ring leaves more room for blood to flow through the Freestyle bioprosthesis. (medtronic.com)
  • The Freestyle aortic root bioprosthesis is the evolutionary result of more than 30 years of experience in tissue technology. (medtronic.com)
  • A prospective non-randomized multicenter clinical study was performed to evaluate the Freestyle bioprosthesis. (medtronic.com)
  • The stentless Prestyled Freestyle ™ bioprosthesis is available in widely used configurations. (medtronic.com)
  • A pre-trimmed version of the Freestyle ® aortic root bioprosthesis to match your preferred implant technique - the complete or modified sub-coronary. (medtronic.com)
  • The objective of this study was to determine normal Doppler and 2-dimensional characteristics of the Freestyle stentless aortic bioprosthesis. (ox.ac.uk)
  • The Freestyle aortic bioprosthesis is a new type of aortic xenograft, and experience is limited. (ox.ac.uk)
  • Even so, the editorial suggested that "it would be interesting to consider whether individuals with elevations in one or more of these biomarkers should be counseled to forego the use of a bioprosthesis and be offered a more durable mechanical valve . (medpagetoday.com)
  • Transthoracic echocardiography (TTE) revealed global hypokinesis of the left ventricle (ejection fraction, EF 35%), severe stenosis (Vmax 5.6 m/s, max/mean gradient 125/77 mm Hg, indexed aortic valve area 0.24 cm2/m2) and moderate regurgitation of the aortic bioprosthesis. (termedia.pl)
  • Objective: The aim of this retrospective study was to compare early postoperative outcomes after aortic valve replacement (AVR) with sutureless bioprostheses and conventional stented bioprostheses implanted through median sternotomy. (northumbria.ac.uk)
  • A postoperative echocardiogram was done, which demonstrated a competent aortic bioprosthesis with no evidence of leak. (ctsnet.org)
  • Additionally, feedback information coming from bioprosthesis sensors on the correct/incorrect classification is applied to the adjustment of the combining mechanism during MCS operation through adaptive tuning competences of base classifiers depending on their decisions (dynamic mode). (easychair.org)
  • We present a case of a 66-year-old man after the mini-Bentall procedure with severe dysfunction of the aortic bioprosthesis (Trifecta GT 25 mm), admitted to the cardiology department due to exacerbation of chronic heart failure to NYHA class III. (termedia.pl)
  • IMSEAR at SEARO: Balloon valvuloplasty of stenosed Carpentier-Edwards bioprosthesis at pulmonary position. (who.int)
  • Oomman A, Ramachandran P, Subramanyan K. Balloon valvuloplasty of stenosed Carpentier-Edwards bioprosthesis at pulmonary position. (who.int)
  • We report a case where balloon dilation of the stenosed bioprosthesis at pulmonary position was successfully performed with good immediate result. (who.int)
  • Our hope is that one day this ovarian bioprosthesis is really the ovary of the future," Northwestern researcher and coauthor Teresa Woodruff told The Guardian . (the-scientist.com)
  • Or whether lifestyle interventions or drug therapy could be offered before AVR to improve these metabolic parameters with the hope of avoiding repeat AVR, if a bioprosthesis is required. (medpagetoday.com)
  • In porcine and ovine models without mitral regurgitation, transapical mitral implantation of the Tiara valve is technically feasible and safe, and results in a stable and well-functioning mitral bioprosthesis. (mit.edu)
  • From July 2017 to July 2018, 60 patients underwent implantation of the Dafodil pericardial bioprosthesis. (biomedcentral.com)
  • The application of advanced echocardiography is useful not only in a preclinical experimental stage but results to be an irreplaceable tool in the proper selection of the treatment strategy with respect to the case-specific anatomic and functional mitral valve (MV) disease pattern and in the guidance of the correct bioprosthesis positioning and implantation during the procedure. (unipd.it)
  • Aims: To describe the feasibility and advantage of 3D and contrast echocardiography in a preclinical study and report the acute hemodynamic results after implantation of a novel transcatheter self- expandable D-shape mitral bioprosthesis characterized by asymmetric stent and advanced mono- leaflet structure. (unipd.it)
  • Conclusions: Both configurations of this newly designed stentless mitral bioprosthesis, which preserves annular-papillary muscle continuity using different novel surgical implantation techniques, demonstrated reliable valve performance, with low transvalvular pressure gradients, minimal regurgitation, and acutely preserved postimplant left ventricular function. (elsevier.com)
  • Biological heart valves in different sizes are bioprostheses manufactured from porcine hearts for human implantation. (brainkart.com)
  • Meanwhile, in a separate CoreValve Trial update also presented at TCT 2014, investigators found that patients with severe aortic stenosis deemed at extreme risk for surgery whom underwent TAVR using a self-expanding bioprosthesis, continued to see low rates of all-cause mortality and stroke two years after the procedure. (acc.org)
  • One-year results from the study presented at TCT 2013 supported the safety and efficacy of the self-expanding bioprosthesis in patients unsuitable for surgical aortic valve replacement. (acc.org)
  • Final 5-year clinical and echocardiographic results for treatment of severe aortic stenosis with a self-expanding bioprosthesis from the ADVANCE Study. (medtronic.com)
  • Background In patients at increased surgical risk, TAVR with a self-expanding bioprosthesis is associated with improved 1-year survival compared with AVR. (houstonmethodist.org)
  • Background: The Tiara is a transcatheter self-expanding mitral bioprosthesis, specifically designed for the complex anatomic configuration of the mitral apparatus. (mit.edu)
  • 15. Transcatheter pulmonary valve replacement using the melody valve for treatment of dysfunctional surgical bioprostheses: A multicenter study. (nih.gov)
  • Does the use of a stentless bioprosthesis increase surgical risk? (ox.ac.uk)
  • Stentless aortic bioprostheses (SBPs) convey hemodynamic and perhaps survival benefit over stented counterparts. (ox.ac.uk)
  • We also reviewed hospital mortality in the stentless bioprosthesis literature and compared this with the Society of Thoracic Surgery Database. (ox.ac.uk)
  • This study was conducted to evaluate the morphometrical and biomechanical properties of the stentless Medtronic Freestyle™ aortic root bioprosthesis, to identify any arising problem areas, and to speculate on a potential solution. (elsevier.com)
  • Methods: The three-dimensional heterogeneity of the stentless bioprosthesis wall was investigated using computed tomography. (elsevier.com)
  • Conclusions: Based on the morphometrical and biomechanical analyses of the stentless bioprosthesis, we demonstrated that there are differences in wall thickness and elasticity between each sinus of Valsalva. (elsevier.com)
  • The exclusion of the non-coronary sinus of Valsalva may be beneficial to mitigate the long-term risks of tissue failure in the stentless bioprosthesis. (elsevier.com)
  • Symetis Acurate TA™ Aortic Bioprosthesis The Symetis Acurate valve (Symetis, Lausanne, Switzerland) consists Bay 11-7085 of an aortic stentless porcine valve that is mounted and sutured in a self-expanding nitinol alloy stent (Figure 3) with a Dacron interface at the lower part of the stent frame. (inhibitorlibraries.com)
  • Three hundred ninety-five TAVR and 402 SAVR patients were prospectively enrolled and randomized 1:1 to TAVR with a CoreValve bioprosthesis or a surgical bioprosthetic valve. (houstonmethodist.org)
  • The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. (regionh.dk)
  • Effect of ethanol and ether in the prevention of calcification of bioprostheses. (structuralheart.abbott)
  • We excluded all described causes related with early bioprosthesis calcification and degeneration. (clinmedjournals.org)
  • Explanted Carpentier-Edwards Perimount bioprosthesis (view from the left ventricule: A, view from the left atrium: B showing a tear in leaflet 1 (white arrow). (biomedcentral.com)
  • The latest results of the Perigon Study, presented by Prof. Dr. Robert J.M. Klautz during EACTS 2021: Surgical Aortic Valve Replacement with a Stented Pericardial Bioprosthesis: 5-year Outcomes. (medtronic.com)
  • In this retrospective study with matched populations, the RDAVR with the INTUITY valve system provided superior procedural and hemodynamic outcomes than a standard bioprosthesis without compromising safety. (uzh.ch)
  • by International Symposium on Cardiac Bioprostheses (3rd: 1985 : London, U.K. (who.int)
  • Types of malfunction Structural valve deterioration The principal complication plaguing cardiac bioprostheses is structural deterioration, often necessitating reoperation and prosthesis replacement. (dermatologyadvisor.com)
  • Current heart valve prostheses may be classified as either mechanical or tissue valves (bioprostheses). (elsevier.com)
  • An aortic homograft was implanted with preserved anterior mitral leafl et which allowed a complete resection of infected tissue and anchoring of mitral bioprosthesis. (muni.cz)
  • However, some primary tissue failures in bioprostheses have been reported. (elsevier.com)
  • Bioprosthesis was independently associated with 1-year mortality (hazard ratio: 1.298). (uab.edu)
  • The mitroflow aortic prosthesis is a bovine pericardial bioprosthesis specially designed to increase the valve area in relation to its size. (rosannemetz.com)
  • Hemodynamic evaluation of the Sorin Soprano bioprosthesis in the completely supra-annular aortic position. (tum.de)
  • The overall risk for svd is high for the mitroflow bioprosthesis, especially if the prosthesis is small and older than 5 years. (rosannemetz.com)
  • The valve was resected, and a 27-mm Mosaic mitral bioprosthesis was implanted in its place. (biomedcentral.com)
  • A 64-year-old woman received 29 mm Mosaic mitral bioprosthesis in 2010 after failure of valve repair attempt. (bmj.com)
  • Diagnosis of possible infectious endocarditis in the patient was suspected after results of a transesophageal echocardiogram were used as a major criterion (thickened and partial aortic stenosis), and predisposing heart condition (aortic bioprosthesis) were used as a minor criterion ( 3 ) Because blood cultures were negative for the organism, the diagnosis of B . henselae infection was made by using serologic analysis and PCR ( 7 ). (cdc.gov)
  • Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. (cfsremission.com)
  • For the first time, the quantitative evaluation of the αGal epitope in heart valve bioprostheses, already in clinical practice for about 40 yrs, was finally determined. (nih.gov)
  • The clinical safety and performance of the Dafodil pericardial bioprosthesis were favourable at 12-month. (biomedcentral.com)
  • We compare clinical and hemodynamic results after AVR with three bioprostheses with different design and characteristics. (unicatt.it)
  • He had had an aortic valve replacement and a bioprosthesis was inserted in 2005 for rheumatic disease. (cdc.gov)
  • BPVT is, simply put, thrombosis forming over a bioprosthesis. (medscape.com)
  • The application of advanced echocardiography on an animal model was feasible and helpful in guiding the continuous refinements needed to enhance the development of this new concept of bioprosthesis. (unipd.it)
  • LeMaitre Vascular has acquired the ProCol vascular bioprosthesis product line from Hancock Jaffe Laboratories for US$665,000 plus a three-year royalty. (vascularnews.com)
  • However, cases involving a Ross procedure, in which the aortic valve is replaced with the patient's own pulmonic valve and the pulmonic valve is then replaced with a bioprosthesis is not considered a "multiple valve" procedure and may be evaluated for a special issuance medical certification by the FAA staff physicians. (aopa.org)
  • Bioprosthesis has been increasingly implanted for the treatment of transvalvular disease across the world. (biomedcentral.com)
  • Advances in Anticalcific and Antidegenerative Treatment of Heart Valve Bioprostheses. (structuralheart.abbott)