Schistosoma mansoni
Disease Vectors
Schistosomiasis mansoni
Echinostoma
Snails
Host-Parasite Interactions
Schistosomiasis
Bulinus
Euphorbia
Schistosoma
Niclosamide
Silver Staining
Latex
Oocysts
Egypt
Biological Phenomena
Guadeloupe
Competitive Behavior
Angiostrongylus
Lakes
Saint Lucia
Pest Control, Biological
Lethal Dose 50
Piperaceae
Pest Control
Martinique
Tilapia
Cuba
Random Amplified Polymorphic DNA Technique
DNA, Ribosomal Spacer
Plant Extracts
Ecology
Polymorphism, Restriction Fragment Length
Schistosoma haematobium
Larva
Species Specificity
Polymerase Chain Reaction
Disease Reservoirs
Seasons
Predatory Behavior
Genetic Markers
Environment
Biomphalaria
Molecular Sequence Data
Water
Immunity, Innate
DNA, Ribosomal
DNA, Mitochondrial
Electrophoresis, Polyacrylamide Gel
Amino Acid Sequence
The chemical ecology of Biomphalaria glabrata: the effects of ammonia on the growth rate of juvenile snails. (1/343)
When juvenile specimens of Biomphalaria glabrata were subjected to concentrations of ammonia ranging from 1-100 mug/ml in various media the following effects were observed: the addition of ammonia to borate buffered media caused mortality. Both borate and tris-buffered media caused a decrease in the growth rate of snails when compared with controls in SSW. The growth rates of the snails could be enhanced by increasing the concentration of ammonia to critical thresholds, but further increases beyond these thresholds resulted in growth inhibition. The toxicity of ammonia in ambient water was augmented by an an increase in pH. The possible causation and ecological significance of these effects are discussed. There are indications that the snails are physiologically well-adapted to utilize ammonia when required and also to control its excretion and uptake from the medium. (+info)Interleukin 5 (IL-5) is not required for expression of a Th2 response or host resistance mechanisms during murine schistosomiasis mansoni but does play a role in development of IL-4-producing non-T, non-B cells. (2/343)
During schistosomiasis, interleukin-5 (IL-5)-dependent eosinophil responses have been implicated in immunopathology, resistance to superinfection, synergistic interactions with chemotherapeutic agents, and the inductive phase of the egg-induced Th2 response. We examined these issues in IL-5-deficient (IL-5(-/-)) mice. IL-5(-/-) and wild-type (WT) mice were indistinguishable in terms of susceptibility to primary infections and the ability to resist secondary infections. Moreover, hepatic pathology was similar in both strains apart from a relative lack of eosinophils and, during chronic infection, a significantly larger mast cell component in the granulomas of IL-5(-/-) mice. Splenocyte cytokine production in response to soluble egg antigen (SEA) or anti-CD3 revealed no significant differences except for heightened tumor necrosis factor alpha production by cells from chronically infected IL-5(-/-) mice compared to WT animals. In contrast, ionomycin-stimulated non-B, non-T (NBNT) cells from IL-5(-/-) mice produced significantly smaller IL-4 amounts than did NBNT cells from WT animals. This difference was not apparent following plate-bound anti-immunoglobulin E or SEA stimulation. The absence of IL-5 failed to affect the induction of Th2 responses in naive mice. Peritoneal exudate cells recovered from egg-injected IL-5(-/-) or WT mice produced equivalent levels of IL-4 following restimulation with SEA or anti-CD3. (+info)Geographic information systems and the environmental risk of schistosomiasis in Bahia, Brazil. (3/343)
A geographic information system was constructed using maps of regional environmental features, Schistosoma mansoni prevalence in 30 representative municipalities, and snail distribution in Bahia, Brazil to study the spatial and temporal dynamics of infection and to identify environmental factors that influence the distribution of schistosomiasis. Results indicate that population density and the duration of annual dry period are the most important determinants of prevalence of schistosomiasis in the areas selected for study. Maximum rainfall, total precipitation during three consecutive months, annual maximum or minimum temperatures, and diurnal temperature difference were not shown to be significant factors influencing S. mansoni prevalence in local populations or distribution of snail hosts. Prevalence of the disease was highest in the coastal areas of the state. Higher prevalence tended to occur in areas with latossolo soil type and transitional vegetation. (+info)Intranasal administration of synthetic recombinant peptide-based vaccine protects mice from infection by Schistosoma mansoni. (4/343)
Schistosomiasis is the cause of a chronic debilitating disease which accounts for significant mortality and morbidity every year, especially in tropical and subtropical areas. An epitope derived from the protective surface protein 9B-Ag of Schistosoma mansoni, designated 9B peptide-1, was previously showed to be protective in mice when conjugated to bovine serum albumin and administered subcutaneously in complete Freund's adjuvant. In this work, this protective peptide was expressed in the flagellin of a Salmonella vaccine strain, and the isolated recombinant flagella were used for immunization of mice. Since during the invasion of the parasite into the host the schistosomula migrate first to the lungs, the intranasal route of administration was employed in order to halt the parasite at an early stage of the infection. Such intranasal immunization with this peptide expressed in flagellin, without the addition of adjuvants, resulted in a significant humoral response and also led to protection against challenge infection, manifested as a reduction of the worm burden by an average of 42%. (+info)The epidemiology of a recent focus of mixed Schistosoma haematobium and Schistosoma mansoni infections around the 'Lac de Guiers' in the Senegal River Basin, Senegal. (5/343)
A village with mixed Schistosoma mansoni and S. haematobium infections (probably in a early endemic phase) was identified around the Lac de Guiers in the Senegal River Basin. In documenting the epidemiology of both schistosomes, we focused on prevalence and intensity of infection, transmission patterns and the impact of treatment. S. mansoni prevalences (near 100%) and egg counts (overall geometric mean eggs per gram of faeces (epg) of 589 were high in all age groups, with 35% of individuals excreting > 1000 epg, and showing a slow decline in egg output only after the age of 30 years. The overall prevalence (28%) and egg counts (2% > 50 eggs/10 ml) of S. haematobium were low, with mean counts of 6.3 eggs/10 ml. Maximal mean S. mansoni egg counts were found in 5-9 year-old boys and in 15-19 year-old girls; S. haematobium maximal counts in 1-4 year-old boys and in girls aged 5-9. Extremely high Biomphalaria pfeifferi infection ratios were recorded over the whole year. Following a single treatment, re-infection was rapid with prevalences and mean egg counts of both Schistosoma species reaching pretreatment levels within 7 months. (+info)Changes in the behavioral and immunological parameters of the mollusk Biomphalaria tenagophila induced by disruption of the circadian cycle as a consequence of continuous illumination. (6/343)
In the present investigation we studied some behavioral and immunological parameters of adult gastropod mollusk, Biomphalaria tenagophila, which have been reproducing for several generations under laboratory conditions. One group of gastropods was kept on a 14-h light/10-h dark cycle, corresponding to a regular circadian cycle, and another group was exposed to continuous light for 48 h. Animals were studied along (behavioral groups) or immediately after (immunological groups) 48 h of regular circadian cycle or continuous light conditions. Stopping/floating, dragging and sliding were the behavioral aspects considered (N = 20 for regular cycle; N = 20 for continuous illumination) and number of hemocytes/microl hemolymph was the immunological parameter studied (N = 15 for regular cycle, N = 14 for continuous illumination). Animals under continuous illumination were more active (sliding = 33 episodes, dragging = 48 episodes) and displayed a lower number of hemocytes (78.0 +/- 24. 27/microl) when compared with mollusks kept on a regular circadian cycle (sliding = 18 episodes, dragging = 27 episodes; hemocytes = 157.6 +/- 53.27/microl). The data are discussed in terms of neural circuits and neuroimmunological relations with the possible stressful effect of continuous illumination. (+info)Profile of organic acid concentrations in the digestive gland and hemolymph of Biomphalaria glabrata under estivation. (7/343)
Using high performance liquid chromatography (HPLC) analysis it was possible to determine simultaneously the concentration of organic acids (pyruvate, lactate, succinate, fumarate, malate, acetate, propionate, acetoacetate, and ss-hydroxybutyrate) in the digestive gland and the extracellular concentration of these same acids in the hemolymph of estivating Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. After a 7 day period of estivation, there was a significant increase in the tissue levels of lactate, succinate, malate and acetate compared to non-estivating snails. After 14 days of estivation, the levels of lactate and acetate were also significantly elevated. The hemolymph concentrations of pyruvate and acetate increased significantly after 7 days and acetate concentrations continued to be significantly increased up to 14 days of estivation. The other organic acids studied, such as ketone body acetoacetate and ss-hydroxybutyrate or the volatile acid propionate, did not accumulate. Their tissue concentrations, however, increased on the 7th day of estivation and reached normal levels within two weeks of estivation for some of them. One should take into consideration how the reduction in metabolism can be handled under aerobic conditions, and what role anaerobic pathways may play in both energy formation and redox balance processes. (+info)Growth changes induced by gamma radiation on Biomphalaria straminea (Dunker, 1848). (8/343)
Doses of 60Co gamma radiation with 2.5; 5; 7.5; 10; 15; 20; 25; 30; 35; 40; 45; 50; 55; 60; 80; 160; 320 and 640 Gy were applied to 1, 080 snails Biomphalaria straminea, an intermediate host of Schistosoma mansoni, divided in groups containing 30 mollusks. In addition, 60 non irradiated snails were kept as control. Fifty percent of the population was kept in colonies (allowing cross fertilization) while the other half was maintained in sexual isolation (allowing self fertilization) and during one month their growth was observed through the daily measurement of the shell diameter. Results showed that after 20 Gy doses the growth in shell diameter of irradiated snails was greater than that of the control group after 30 days. At this dose the snail size was the greatest, among all isolated groups. The 80 Gy doses also induced the final shell diameter of isolated snails to be greater then that observed in the control groups. As this effect was most evident among the isolated snails, a possible hormonal role may have been involved in the observed phenomena, which is under investigation with the objective of identifying any future applications that this could have to schistosomiasis control. (+info)The infection occurs when the parasitic worm enters the body through the skin, usually during contact with infected water. The schistosomes migrate to the liver and intestines, where they cause inflammation and damage to the host tissues.
Symptoms of schistosomiasis mansoni can include abdominal pain, diarrhea, fatigue, and weight loss. If left untreated, it can lead to serious complications such as anemia, liver and kidney damage, and even death.
Diagnosis is based on the presence of schistosome eggs in the urine or stool, and treatment typically involves a combination of antiparasitic drugs and supportive care to manage symptoms. Prevention measures include avoiding contact with contaminated water and using snail-killing agents to reduce the number of intermediate hosts.
There are two main types of schistosomiasis:
1. Schistosoma haematobium: This type is most commonly found in Africa and the Middle East, and affects the urinary tract, causing bleeding, kidney damage, and bladder problems.
2. Schistosoma japonicum: This type is found in Asia, and affects the intestines, causing abdominal pain, diarrhea, and rectal bleeding.
3. Schistosoma mansoni: This type is found in sub-Saharan Africa, and affects both the intestines and the liver, causing abdominal pain, diarrhea, and liver damage.
Symptoms of schistosomiasis can include:
* Bloody urine
* Abdominal pain
* Diarrhea
* Rectal bleeding
* Fatigue
* Anemia
* Weight loss
If left untreated, schistosomiasis can lead to serious complications such as kidney damage, bladder cancer, and infertility.
Treatment of schistosomiasis typically involves the use of praziquantel, an antiparasitic drug that is effective against all species of Schistosoma. In addition to treatment, preventive measures such as avoiding contact with contaminated water and using protective clothing when swimming or bathing in areas where the disease is common can help reduce the risk of infection.
Preventive measures for schistosomiasis include:
* Avoiding contact with contaminated water
* Using protective clothing such as long sleeves and pants when swimming or bathing in areas where the disease is common
* Avoiding activities that involve exposure to water, such as swimming or fishing, in areas where the disease is common
* Using clean water for drinking, cooking, and personal hygiene
* Implementing sanitation measures such as building latrines and improving sewage systems in areas where the disease is common
It is important to note that schistosomiasis is a preventable and treatable disease, but it requires awareness and action from individuals, communities, and governments to control and eliminate the disease.
The clinical manifestations of echinostomiasis are varied and can include hematuria, dysuria, urinary frequency, flank pain, and bladder mass lesions. The diagnosis is based on the presence of characteristic eggs in urine or stool samples, or on the detection of adult worms during cystoscopy or imaging studies such as ultrasound or computed tomography (CT) scan.
Treatment of echinostomiasis typically involves the use of antiparasitic drugs, such as praziquantel or triclabendazole, which are effective in killing the adult worms and preventing further egg production. Surgical intervention may be necessary in cases with large bladder stones or hydronephrosis.
Preventive measures against echinostomiasis include education on safe water drinking practices, use of clean water for irrigation and cooking, and avoidance of raw or undercooked fish consumption.
In conclusion, echinostomiasis is a rare and neglected parasitic infection that can cause significant morbidity and mortality in certain regions of the world. Early diagnosis and treatment are essential to prevent complications and reduce the risk of transmission.
Biomphalaria
Biomphalaria straminea
Biomphalaria angulosa
Biomphalaria stanleyi
Biomphalaria peregrina
Biomphalaria tchadiensis
Biomphalaria andecola
Biomphalaria glabrata
Biomphalaria kuhniana
Biomphalaria smithi
Biomphalaria schrammi
Biomphalaria tenagophila
Biomphalaria sudanica
Biomphalaria alexandrina
Biomphalaria salinarum
Biomphalaria barthi
Biomphalaria pfeifferi
Biomphalaria havanensis
Biomphalaria camerunensis
FMRFamide in Biomphalaria glabrata
List of non-marine molluscs of Benin
List of non-marine molluscs of Nigeria
List of non-marine molluscs of Honduras
Angiostrongylus vasorum
Red-rimmed melania
Capsaspora
Indoplanorbis
Schistosoma mansoni
Bulinus africanus
Radix natalensis
Establishment of Biomphalaria tenagophila Snails in Europe - Volume 14, Number 11-November 2008 - Emerging Infectious Diseases...
A suction dredge for collecting Biomphalaria and other molluscs from deep water.
SciELO - Brazil - The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata The influence of...
Results of search for 'su:{Biomphalaria.}'
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WHO HQ Library catalog
Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
First report of Biomphalaria tenagophila (d'Orbigny, 1835) (Gastropoda/Planorbidae) in Pará State, Amazon region of Brazil. |...
CDC - Schistosomiasis
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Total Synthesis of Ricciocarpin A by List
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Schistosoma mansoni Infection in Holochilus sciureus Shows Sex-Related Differences in Parasitological Patterns
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Glabrata15
- Of the 34 Biomphalaria species, 4 ( B. glabrata, B. pfeifferi, B. straminea , and B. tenagophila ) have recently expanded their native ranges ( 3 ). (cdc.gov)
- Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. (scielo.br)
- Two main types of hemocytes (granulocytes and hyalinocytes) occur in the hemolymph of the mollusk Biomphalaria glabrata . (scielo.br)
- The first generation of Biomphalaria snails collected from five Egyptian governorates (Giza, Fayoum, Kafr El-Sheikh, Ismailia and Damietta) were subjected to species-specific PCR assays and the results showed that snails collected from the field were B. alexandrina, and there was no evidence for the presence of B. glabrata. (scirp.org)
- According to the results of species-specific polymerase chain reaction assays that sampled both nuclear and mitochondrial genomes, and according to DNA sequence data, they found that all Biomphalaria collected during this survey were B. alexandrina and there was no evidence of the presence of B. glabrata or of hybridization of B. alexandrina with B. glabrata in the examined sites. (scirp.org)
- In a total of 505 scaffolds (N50 = 3.2Mb), 430 were assigned to 18 large linkage groups inferred to represent the 18 known chromosomes, based on whole genome comparisons with Biomphalaria glabrata. (diagenode.com)
- Studies on the host snails of schistosomiasis from north-east Brazil, with special reference to diapause in Biomphalaria glabrata (Say / by Otavio Sarmento Pieri. (who.int)
- The snail Biomphalaria glabrata is one of the intermediate hosts of S. mansoni. (swan.ac.uk)
- Foram utilizadas progênies de moluscos Biomphalaria tenagophila e Biomphalaria glabrata selecionadas para o caráter susceptibilidade ao S. mansoni das linhagens SJ e BH, respectivamente. (scielosp.org)
- H+ channels in embryonic Biomphalaria glabrata cell membranes: Putative roles in snail host-schistosome interactions. (nih.gov)
- Proteomic analysis of Biomphalaria glabrata plasma proteins with binding affinity to those expressed by early developing larval Schistosoma mansoni. (nih.gov)
- The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni. (nih.gov)
- Ricciocarpin A is indeed active against Biomphalaria glabrata water snails, which are vector of schistosomiasis, a nasty tropical disease. (organic-chemistry.org)
- NIAID also helped support the 2017 genome sequencing of the tropical freshwater Ram's Horn snail, Biomphalaria glabrata , which S. mansoni parasites require to complete their life cycle. (nih.gov)
- Currently, NIAID investigators are working on sequencing the genomes of two other important NTD vectors: the tsetse fly, which transmits T. brucei to humans, and the freshwater snail Biomphalaria glabrata , which transmits a parasite that causes schistosomiasis. (nih.gov)
Schistosoma6
- Among Schistosoma species that affect humans, Schistosoma mansoni is the most likely to invade new areas mainly because of the adaptability and invasiveness of its intermediate host, Biomphalaria snails. (cdc.gov)
- 1958). Intermediate hosts of schistosoma : African Biomphalaria and Bulinus / G. Mandahl-Barth. (who.int)
- A genome sequence for Biomphalaria pfeifferi, the major vector snail for the human-infecting parasite Schistosoma mansoni. (diagenode.com)
- BACKGROUND: Biomphalaria pfeifferi is the world's most widely distributed and commonly implicated vector snail species for the causative agent of human intestinal schistosomiasis, Schistosoma mansoni. (diagenode.com)
- Les hôtes intermédiaires de schistosoma : Biomphalaria et Bulinus africains / G. Mandahl-Barth. (who.int)
- The snails of the genus Biomphalaria were analyzed for the presence of Schistosoma mansoni cercariae and the molecular identification (only mollusks from Brejo Santo-CE) for differentiation between species. (bvsalud.org)
Snails3
- 5] reported that Biomphalaria snails were widely distributed in the Nile Delta and along the Nile as far south as Aswan. (scirp.org)
- The present study was initiated to identify Biomphalaria snails collected from certain water courses in 5 Egyptian governorates during 2009 using species specific PCR assay and calculating the similarity coefficients among different snail strains collected from these governorates using RAPD-PCR of their DNA. (scirp.org)
- In this study, populations of Biomphalaria snails from some water courses in 5 Egyptian (Giza, Fayoum, Kafr El-Sheikh, Ismailia and Damietta) were collected and reared in the laboratory and their offspring (F 1 ) were used throughout this study. (scirp.org)
Straminea2
- The ecology of Biomphalaria straminea (Dunker, 1848 (Gastropoda : pulmonata introduced into Hong Kong. (who.int)
- Biomphalaria straminea (Porcos Stream ) and Biomphalaria kuhniana was identified in the Boi 1 and Cipo reservoirs (Brejo Santo). (bvsalud.org)
Schistosomiasis1
- Identification of Biomphalaria species is important to further understand the schistosomiasis epidemiology. (scirp.org)
Species4
- They have been introduced to areas where other Biomphalaria species are endemic (e.g. (cdc.gov)
- Morphological studies of Biomphalaria species identification have been widely carried out and differentiation between some species may be difficult mainly due to phenotypic similarities, size of collected specimens and inadequate fixation procedures [1]. (scirp.org)
- 4] utilized RAPD-PCR to differentiate species and populations of Biomphalaria from Egypt and other countries. (scirp.org)
- The following species were found Biomphalaria sp. (bvsalud.org)
Tenagophila1
- A) Shell morphology of Biomphalaria tenagophila snail from Romania. (cdc.gov)
Bulinus1
- Los huéspedes intermediarios del esquistosoma : formas africanas de los géneros Biomphalaria y Bulinus / G. Mandahl-Barth. (who.int)
Identification2
- Considering the fact that morphological identification may become difficult or even impossible under particular circumstances, the use of molecular-based methods have permitted the generation of more consistent information concerning the population structure of Biomphalaria furthering knowledge on taxonomy and diagnosis of infection. (scirp.org)
- Identification of Biomphalaria sp. (bvsalud.org)
Specimens1
- In and beside an abandoned concrete pool next to the spring, we collected 100 shells and 34 living specimens that macroscopically resembled Biomphalaria spp. (cdc.gov)
Search1
- Results of search for 'su:{Biomphalaria. (who.int)
Water1
- A suction dredge for collecting Biomphalaria and other molluscs from deep water. (who.int)
Snail2
- A) Shell morphology of Biomphalaria tenagophila snail from Romania. (cdc.gov)
- In Uganda , it is endemic at both Lake Albert (LA) and Lake Victoria (LV) and caused by S. mansoni that uses Biomphalaria snails as obligatory intermediate snail hosts. (bvsalud.org)
Mansoni3
- Among Schistosoma species that affect humans, Schistosoma mansoni is the most likely to invade new areas mainly because of the adaptability and invasiveness of its intermediate host, Biomphalaria snails. (cdc.gov)
- Seasonal patterns of Schistosoma mansoni infection within Biomphalaria snails at the Ugandan shorelines of Lake Albert and Lake Victoria. (bvsalud.org)
- To shed light on local patterns of infection , we utilised two PCR -based methods to detect S. mansoni within Biomphalaria spp. (bvsalud.org)
Pfeifferi2
- Three species of Biomphalaria , B. pfeifferi, B. stanleyi and B. sudanica, were identified at our Lake Albert collection sites, while only a single species, B. choanomphala, was identified at our Lake Victoria collection sites. (bvsalud.org)
- 5%). Of the Biomphalaria species identified, B. choanomphala had the highest haplotype ( gene ) diversity score, followed by B. stanleyi, B. sudanica and B. pfeifferi. (bvsalud.org)
Species1
- They have been introduced to areas where other Biomphalaria species are endemic (e.g. (cdc.gov)