A ketose sugar that is commonly used in the commercial synthesis of ASCORBIC ACID.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.
The directed transport of ORGANELLES and molecules along nerve cell AXONS. Transport can be anterograde (from the cell body) or retrograde (toward the cell body). (Alberts et al., Molecular Biology of the Cell, 3d ed, pG3)
The movement of ions across energy-transducing cell membranes. Transport can be active, passive or facilitated. Ions may travel by themselves (uniport), or as a group of two or more ions in the same (symport) or opposite (antiport) directions.
Membrane proteins whose primary function is to facilitate the transport of molecules across a biological membrane. Included in this broad category are proteins involved in active transport (BIOLOGICAL TRANSPORT, ACTIVE), facilitated transport and ION CHANNELS.
The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
A large group of membrane transport proteins that shuttle MONOSACCHARIDES across CELL MEMBRANES.
The rate dynamics in chemical or physical systems.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The process by which ELECTRONS are transported from a reduced substrate to molecular OXYGEN. (From Bennington, Saunders Dictionary and Encyclopedia of Laboratory Medicine and Technology, 1984, p270)
Transport proteins that carry specific substances in the blood or across cell membranes.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Vesicles that are involved in shuttling cargo from the interior of the cell to the cell surface, from the cell surface to the interior, across the cell or around the cell to various locations.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Established cell cultures that have the potential to propagate indefinitely.
Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.
Membrane proteins whose primary function is to facilitate the transport of negatively charged molecules (anions) across a biological membrane.
Membrane proteins whose primary function is to facilitate the transport of positively charged molecules (cations) across a biological membrane.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
A stack of flattened vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough ENDOPLASMIC RETICULUM and directing them to secretory vesicles, LYSOSOMES, or the CELL MEMBRANE. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus and fuse with the Golgi, lysosomes or cell membrane. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990)
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A broad category of proteins involved in the formation, transport and dissolution of TRANSPORT VESICLES. They play a role in the intracellular transport of molecules contained within membrane vesicles. Vesicular transport proteins are distinguished from MEMBRANE TRANSPORT PROTEINS, which move molecules across membranes, by the mode in which the molecules are transported.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Cellular proteins and protein complexes that transport amino acids across biological membranes.
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
Elements of limited time intervals, contributing to particular results or situations.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.

Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. (1/29779)

Drosophila Armadillo and its vertebrate homolog beta-catenin are key effectors of Wingless/Wnt signaling. In the current model, Wingless/Wnt signal stabilizes Armadillo/beta-catenin, which then accumulates in nuclei and binds TCF/LEF family proteins, forming bipartite transcription factors which activate transcription of Wingless/Wnt responsive genes. This model was recently challenged. Overexpression in Xenopus of membrane-tethered beta-catenin or its paralog plakoglobin activates Wnt signaling, suggesting that nuclear localization of Armadillo/beta-catenin is not essential for signaling. Tethered plakoglobin or beta-catenin might signal on their own or might act indirectly by elevating levels of endogenous beta-catenin. We tested these hypotheses in Drosophila by removing endogenous Armadillo. We generated a series of mutant Armadillo proteins with altered intracellular localizations, and expressed these in wild-type and armadillo mutant backgrounds. We found that membrane-tethered Armadillo cannot signal on its own; however it can function in adherens junctions. We also created mutant forms of Armadillo carrying heterologous nuclear localization or nuclear export signals. Although these signals alter the subcellular localization of Arm when overexpressed in Xenopus, in Drosophila they have little effect on localization and only subtle effects on signaling. This supports a model in which Armadillo's nuclear localization is key for signaling, but in which Armadillo intracellular localization is controlled by the availability and affinity of its binding partners.  (+info)

Meiosis: MeiRNA hits the spot. (2/29779)

The protein Mei2 performs at least two functions required in fission yeast for the switch from mitotic to meiotic cell cycles. One of these functions also requires meiRNA. It appears that meiRNA targets Mei2 to the nucleus, where it can promote the first meiotic division.  (+info)

Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. (3/29779)

The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water channels facilitate fluid movement between airspace, interstitial, and capillary compartments, we measured passive and active fluid transport in AQP1 and AQP4 knockout mice. Airspace-capillary osmotic water permeability (Pf) was measured in isolated perfused lungs by a pleural surface fluorescence method. Pf was remarkably reduced in AQP1 (-/-) mice (measured in cm/s x 0.001, SE, n = 5-10: 17 +/- 2 [+/+]; 6.6 +/- 0.6 AQP1 [+/-]; 1.7 +/- 0.3 AQP1 [-/-]; 12 +/- 1 AQP4 [-/-]). Microvascular endothelial water permeability, measured by a related pleural surface fluorescence method in which the airspace was filled with inert perfluorocarbon, was reduced more than 10-fold in AQP1 (-/-) vs. (+/+) mice. Hydrostatically induced lung interstitial and alveolar edema was measured by a gravimetric method and by direct measurement of extravascular lung water. Both approaches indicated a more than twofold reduction in lung water accumulation in AQP1 (-/-) vs. (+/+) mice in response to a 5- to 10-cm H2O increase in pulmonary artery pressure for five minutes. Active, near-isosmolar alveolar fluid absorption (Jv) was measured in in situ perfused lungs using 125I-albumin as an airspace fluid volume marker. Jv (measured in percent fluid uptake at 30 min, n = 5) in (+/+) mice was 6.0 +/- 0.6 (37 degrees C), increased to 16 +/- 1 by beta-agonists, and inhibited to less than 2.0 by amiloride, ouabain, or cooling to 23 degrees C. Jv (with isoproterenol) was not affected by aquaporin deletion (18.9 +/- 2.2 [+/+]; 16.4 +/- 1.5 AQP1 [-/-]; 16.3 +/- 1.7 AQP4 [-/-]). These results indicate that osmotically driven water transport across microvessels in adult lung occurs by a transcellular route through AQP1 water channels and that the microvascular endothelium is a significant barrier for airspace-capillary osmotic water transport. AQP1 facilitates hydrostatically driven lung edema but is not required for active near-isosmolar absorption of alveolar fluid.  (+info)

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation. (4/29779)

In COS cells, Ral GDP dissociation stimulator (RalGDS)-induced Ral activation was stimulated by RasG12V or a Rap1/Ras chimera in which the N-terminal region of Rap1 was ligated to the C-terminal region of Ras but not by Rap1G12V or a Ras/Rap1 chimera in which the N-terminal region of Ras was ligated to the C-terminal region of Rap1, although RalGDS interacted with these small GTP-binding proteins. When RasG12V, Ral and the Rap1/Ras chimera were individually expressed in NIH3T3 cells, they localized to the plasma membrane. Rap1Q63E and the Ras/Rap1 chimera were detected in the perinuclear region. When RalGDS was expressed alone, it was abundant in the cytoplasm. When coexpressed with RasG12V or the Rap1/Ras chimera, RalGDS was detected at the plasma membrane, whereas when coexpressed with Rap1Q63E or the Ras/Rap1 chimera, RalGDS was observed in the perinuclear region. RalGDS which was targeted to the plasma membrane by the addition of Ras farnesylation site (RalGDS-CAAX) activated Ral in the absence of RasG12V. Although RalGDS did not stimulate the dissociation of GDP from Ral in the absence of the GTP-bound form of Ras in a reconstitution assay using the liposomes, RalGDS-CAAX could stimulate it without Ras. RasG12V activated Raf-1 when they were coexpressed in Sf9 cells, whereas RasG12V did not affect the RalGDS activity. These results indicate that Ras recruits RalGDS to the plasma membrane and that the translocated RalGDS induces the activation of Ral, but that Rap1 does not activate Ral due to distinct subcellular localization.  (+info)

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA. (5/29779)

The nature of the broad substrate specificity phenomenon, as manifested by multidrug resistance proteins, is not yet understood. In the Escherichia coli multidrug transporter, MdfA, the hydrophobicity profile and PhoA fusion analysis have so far identified only one membrane-embedded charged amino acid residue (E26). In order to determine whether this negatively charged residue may play a role in multidrug recognition, we evaluated the expression and function of MdfA constructs mutated at this position. Replacing E26 with the positively charged residue lysine abolished the multidrug resistance activity against positively charged drugs, but retained chloramphenicol efflux and resistance. In contrast, when the negative charge was preserved in a mutant with aspartate instead of E26, chloramphenicol recognition and transport were drastically inhibited; however, the mutant exhibited almost wild-type multidrug resistance activity against lipophilic cations. These results suggest that although the negative charge at position 26 is not essential for active transport, it dictates the multidrug resistance character of MdfA. We show that such a negative charge is also found in other drug resistance transporters, and its possible significance regarding multidrug resistance is discussed.  (+info)

Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation. (6/29779)

The proton motive force (PMF) renders protein translocation across the Escherichia coli membrane highly efficient, although the underlying mechanism has not been clarified. The membrane insertion and deinsertion of SecA coupled to ATP binding and hydrolysis, respectively, are thought to drive the translocation. We report here that PMF significantly decreases the level of membrane-inserted SecA. The prlA4 mutation of SecY, which causes efficient protein translocation in the absence of PMF, was found to reduce the membrane-inserted SecA irrespective of the presence or absence of PMF. The PMF-dependent decrease in the membrane-inserted SecA caused an increase in the amount of SecA released into the extra-membrane milieu, indicating that PMF deinserts SecA from the membrane. The PMF-dependent deinsertion reduced the amount of SecA required for maximal translocation activity. Neither ATP hydrolysis nor exchange with external SecA was required for the PMF-dependent deinsertion of SecA. These results indicate that the SecA deinsertion is a limiting step of protein translocation and is accelerated by PMF, efficient protein translocation thereby being caused in the presence of PMF.  (+info)

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. (7/29779)

Stimulation of the hepatocyte growth factor (HGF) receptor tyrosine kinase, Met, induces mitogenesis, motility, invasion, and branching tubulogenesis of epithelial and endothelial cell lines in culture. We have previously shown that Gab1 is the major phosphorylated protein following stimulation of the Met receptor in epithelial cells that undergo a morphogenic program in response to HGF. Gab1 is a member of the family of IRS-1-like multisubstrate docking proteins and, like IRS-1, contains an amino-terminal pleckstrin homology domain, in addition to multiple tyrosine residues that are potential binding sites for proteins that contain SH2 or PTB domains. Following stimulation of epithelial cells with HGF, Gab1 associates with phosphatidylinositol 3-kinase and the tyrosine phosphatase SHP2. Met receptor mutants that are impaired in their association with Gab1 fail to induce branching tubulogenesis. Overexpression of Gab1 rescues the Met-dependent tubulogenic response in these cell lines. The ability of Gab1 to promote tubulogenesis is dependent on its pleckstrin homology domain. Whereas the wild-type Gab1 protein is localized to areas of cell-cell contact, a Gab1 protein lacking the pleckstrin homology domain is localized predominantly in the cytoplasm. Localization of Gab1 to areas of cell-cell contact is inhibited by LY294002, demonstrating that phosphatidylinositol 3-kinase activity is required. These data show that Gab1 is an important mediator of branching tubulogenesis downstream from the Met receptor and identify phosphatidylinositol 3-kinase and the Gab1 pleckstrin homology domain as crucial for subcellular localization of Gab1 and biological responses.  (+info)

Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression. (8/29779)

Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. Here we show that signaling triggered by VEGF induced DNA-binding and transcriptional activities of nuclear factor of activated T cells (NFAT) and AP-1 in human umbilical vein endothelial cells (HUVECs). VEGF also induced TF mRNA expression and gene promoter activation by a cyclosporin A (CsA)-sensitive mechanism. As in lymphoid cells, NFAT was dephosphorylated and translocated to the nucleus upon activation of HUVECs, and these processes were blocked by CsA. NFAT was involved in the VEGF-mediated TF promoter activation as evidenced by cotransfection experiments with a dominant negative version of NFAT and site-directed mutagenesis of a newly identified NFAT site within the TF promoter that overlaps with a previously identified kappaB-like site. Strikingly, this site bound exclusively NFAT not only from nuclear extracts of HUVECs activated by VEGF, a stimulus that failed to induce NF-kappaB-binding activity, but also from extracts of cells activated with phorbol esters and calcium ionophore, a combination of stimuli that triggered the simultaneous activation of NFAT and NF-kappaB. These results implicate NFAT in the regulation of endothelial genes by physiological means and shed light on the mechanisms that switch on the gene expression program induced by VEGF and those regulating TF gene expression.  (+info)

Your biology students will learn about the cell membrane and ins-and-outs of cell transport in this engaging, effective, and fun interactive web lesson. The Cell Transport Webquest includes 6 pages of EDITABLE student questions that include fill in the blank and graphic organizer
Get an in-depth review and ask questions about Cell Transport Physiology (part 1/5). See what people are saying about Cell Transport Physiology (part 1/5).
This resource includes everything you need to teach cell transport with little to no prep- and offers many editable resources, as well! The unit includes a suggested unit planner to help guide you through it. These resources are fresh and fun- so if youre looking to diffuse your cell transport materials into a new direction, this is for you! This unit can be used as a stand alone curriculum or as
The transport of S-cysteine conjugates was studied in the kidney cell line, LLC-PK1, using the nephrotoxin, S-(1,2-dichlorovinyl)-L-cysteine (L-DCVC), as the model compound. The saturable uptake of this conjugate did not require sodium and was selectively inhibited by the amino acid transport system L-specific substrate, 2-amino-2-norbornane carboxylic acid, as well as a variety of other S-cysteine conjugates and neutral amino acids with large, nonpolar side chains. Kinetic studies suggested the existence of both low and high affinity transport systems with Km values that differed by 25-fold. Although these uptake systems showed no discernible differences in substrate specificity, the low affinity transport was more sensitive to trans-stimulation. L-DCVC uptake in subconfluent cultures was about 3-fold that of confluent cells, suggesting either adaptive regulation to cell growth or polarization of transport to the basolateral membrane. L-DCVC toxicity in LLC-PK1 cells was inhibited in the ...
Newly synthesized proteins and lipids are transported across the Golgi complex via different mechanisms whose respective roles are not completely clear. We previously identified a non-vesicular intra-Golgi transport pathway for glucosylceramide (GlcCer)--the common precursor of the different series of glycosphingolipids-that is operated by the cytosolic GlcCer-transfer protein FAPP2 (also known as PLEKHA8) (ref. 1). However, the molecular determinants of the FAPP2-mediated transfer of GlcCer from the cis-Golgi to the trans-Golgi network, as well as the physiological relevance of maintaining two parallel transport pathways of GlcCer--vesicular and non-vesicular--through the Golgi, remain poorly defined. Here, using mouse and cell models, we clarify the molecular mechanisms underlying the intra-Golgi vectorial transfer of GlcCer by FAPP2 and show that GlcCer is channelled by vesicular and non-vesicular transport to two topologically distinct glycosylation tracks in the Golgi cisternae and the trans-Golgi
Cell transport is the movement of items into and out of the cell through the cells membrane. This movement is done with a variety of proteins to facilitate the action....
Knowing the structure and properties of the transporter molecule may be the key to changing the way that some chemotherapies, for example, could work in the body to prevent tumor growth, said senior author Seok-Yong Lee, PhD, assistant professor of biochemistry at Duke.. The article was published in Nature online on March 11.. The transporter molecule, called a concentrative nucleoside transporter, works by moving nucleosides, the building blocks of DNA and RNA, from the outside to the inside of cells. It also transports nucleoside-like chemo drugs through cell membranes.. Once inside the cells, the nucleoside-like drugs are modified into nucleotides that are incorporated into DNA in ways that prevent tumor cells from dividing and functioning.. We discovered the structure of the transporter molecule, and now we believe it is possible to improve nucleoside drugs to be better recognized by a particular form of the transporter molecule that resides in certain types of tissue, Lee said. Now we ...
Kucharczyk, R, Kierzek, AM, Slonimski, PP and Rytka, J (2001) The Ccz1p interacts with Ypt7 GTPase in the process of fusion of multiple transport intermediates with the vacuole in S.cerevisiae. ...
RAVINDRA KUMAR, ERRAMPALLI MADHU and ANIL MAAN, Central Road Research Institute, India; SANJEEV SINHA, National Institute of Technology Patna, India Purpose: The purpose of this paper is to determination of Combined Exposure Factor (CEF) of different transport related environmental pollutants by a...
Rapid and extensive biliary excretion of [d-penicillamine2,5]enkephalin (DPDPE) in rats as the unchanged peptide suggests that multiple transport proteins may be involved in the hepatobiliary disposition of this zwitterionic peptide. Although DPDPE is a P-glycoprotein substrate, the role of other transport proteins in the hepatic clearance of DPDPE has not been established. Furthermore, the ability of various experimental approaches to quantitate the contribution of a specific hepatic uptake or excretion process when multiple transport systems are involved has not been addressed. 3H-DPDPE uptake in suspended Wistar rat hepatocytes was primarily (,95%) due to temperature-dependent transport mechanisms; similar results were obtained in suspended hepatocytes from Mrp2-deficient (TR-) rats. Pharmacokinetic modeling revealed that saturable and linear processes were involved in 3H-DPDPE uptake in hepatocytes. The use of transport modulators suggested that hepatic uptake of 3H-DPDPE was mediated by ...
The electronic freight transport information (eFTI) regulation has been approved by the EU and will enter into force in August 2024. It establishes a legal framework for road, rail, maritime and air transport operators to share information with enforcement authorities in an electronic format. This is a crucial step as it entails significant benefits for the EU road freight transport.
Original Message----- , From: Hemant Agrawal ,[email protected], , Sent: Saturday, April 24, 2021 3:37 AM , , From: Nipun Gupta ,[email protected], , , This patch adds two test vectors for transport block in network byte , order: , - LDPC encode for Transport Block , - LDPC decode for Transport block , , Signed-off-by: Nipun Gupta ,[email protected], , --- See related comment on patch 1. Assuming this is a different PMD assumption (not an incremental one) then this should not require new vectors with the op_flag RTE_BBDEV_LDPC_ENC_NETWORK_ORDER. These would artificially create non-compatible vectors for no reason. But all existing vectors should be able to run on any PMD, the test framework will just change order endianness based on what is supported by the device so that all unit test can be run successfully on any PMD. See how it is done for LLR numerical assumptions which can differ between PMDs. Let me know if unclear , app/test-bbdev/test_vectors/ldpc_dec_tb.data , 122 , ...
TY - JOUR. T1 - Potassium transport in normal and transformed mouse 3T3 cells. AU - Spaggiare, S.. AU - Wallach, M. J.. AU - Tupper, J. T.. PY - 1976. Y1 - 1976. N2 - The components of unidirectional K influx and efflux were investigated in the 3T3 cell and the SV40 transformed 3T3 cell in exponential and stationary growth phase. Over the cell densities used for transport experiments the 3T3 cell goes from exponential growth to density dependent inhibition of growth (4 x 104 to 4 x 105 cell cm-2) whereas the SV40 3T3 maintains exponential or near exponential growth (4 x 104 to 1 x 106 cell cm-2). In agreement with previous observations, volume per cell and mg protein per cell decrease with increasing cell density. Thus, transport measurements were expressed on a per volume basis. Total unidirectional K influx and effluxin the 3T3 cell is approximately double that of the SV40 3T3 cell at all cell densities investigated. Both cell types have similar volumes initially and show similar decreases ...
Author: Hasselbach, Wilhelm et al.; Genre: Book Chapter; Published in Print: 1974; Title: Anion specific carriers in the sarcoplasmic membranes
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View Notes - Lecture 26 from KIN 110 at UMass (Amherst). Kin 110Lecture #26 Monday April 12th, 2010 Components of Blood Red blood cells: transport oxygen o Deliver oxygen from lungs to other tissues
Over the last few years scientists have been successful in identifyin...Now Howard Hughes Medical Institute investigator A HREFhttp://ww...If you look at the history of breakthroughs in disease often the u...In the brains of patients with Alzheimers disease a peptide called...Using mouse neurons as a model the scientists showed that APP serv...,Defective,cell,transport,suggested,in,Alzheimers,disease,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
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Cells may be specialised for a particular function.. The structure will allow them to carry this function out.. Leaf cell - Absorbs light energy for photosynthesis, packed with chloroplasts. Regular shaped, closely packed cells from a continuous layer for efficient absorption of sunlight.. Root hair cell - Absorbs water and mineral ions from the soil, long finger-like process with very thin wall, which gives a large surface area. Sperm cell - Fertilises an egg cell - female gamete, the head contains genetic information and an enzyme to help pentrate the egg cell membrane. The middle section is packed with mitochondria for energy. The tail moves the sperm to the egg.. Red blood cells - Contains haemoglobin to carry oxygen to the cells, thin outer membrane to let oxygen diffuse through easily. Shape increases the surface area to allow more oxygen to be absorbed efficiently. No nucleus, so the whole cell is full of haemoglobin.. ...
Some molecules like water fit easily through the openings in the cell membrane. They simply flow in and out, always moving from the side where there are more to the side where there are less of them, or down the concentration gradient from high concentration to low ...
TERM 2002: Paving the way for EU enlargement - Indicators of transport and environment integration. The report examines progress made in the transport sector in implementing the principle, adopted by EU leaders at their Cardiff summit in 1998, of integrating environmental concerns into other policy areas.. Based on a set of key indicators of progress - or lack of it - the report finds that transport trends in both the EU and accession countries are moving away from, not closer to, the main environmental objectives of EU policies on transport and sustainable development.. These call for breaking the close link between economic growth and transport expansion, as well as stabilising the modal split - the market shares of the different transport modes - at 1998 levels by 2010, then shifting traffic from the roads back to rail and inland waterways.. The report shows, for instance, that in the EU and accession countries energy consumption by transport and the associated emissions of greenhouse gases ...
TERM 2002: Paving the way for EU enlargement - Indicators of transport and environment integration. The report examines progress made in the transport sector in implementing the principle, adopted by EU leaders at their Cardiff summit in 1998, of integrating environmental concerns into other policy areas.. Based on a set of key indicators of progress - or lack of it - the report finds that transport trends in both the EU and accession countries are moving away from, not closer to, the main environmental objectives of EU policies on transport and sustainable development.. These call for breaking the close link between economic growth and transport expansion, as well as stabilising the modal split - the market shares of the different transport modes - at 1998 levels by 2010, then shifting traffic from the roads back to rail and inland waterways.. The report shows, for instance, that in the EU and accession countries energy consumption by transport and the associated emissions of greenhouse gases ...
This lab simulates the action potential of a neuron using the membrane channel simulator. Students are directed through the process of setting up their membrane like the membrane of a neuron and performing the steps of an action potential ...
This lab simulates the action potential of a neuron using the membrane channel simulator. Students are directed through the process of setting up their membrane like the membrane of a neuron and performing the steps of an action potential ...
My strengths is that I pay attention in class and take down important notes. From taking down extra notes, I can more information and it also make me understand better. My weakness is that I am not able to spell in familiar words and I will write long answers so I will not have time to complete the paper. I also find it difficult to self-study since I will not know how to study before the test so I just remembered stuff which I was quite weak in and the mistakes I made for the past pop-quiz. And the reason for doing average for my science, I was anxious of not completing the paper so I only got part of the marks. So in the future, before the exam, I think I should read through all the notes and summarize all the topics like what are cancer cells. And in the sentence, I must make sure that I have all the keywords.. ReplyDelete ...
bestbooklibrary matches keywords, searched from 3rd-party sites, to affiliate-networks offering unlimited access to licensed entertainment content. bestbooklibrary allows visitors, otherwise looking for free-content to enjoy more for less. ...
Active and Passive Transport. Chapter 5. 1. Passive Transport . Movement of materials in and out of the cell Requires no energy to happen. Two Types of Passive Transport. Diffusion: When substance moves that is dissolved in water Osmosis: When water moves across the membrane. Slideshow 6854745 by humphrey-askew
Whats the difference between Active Transport and Passive Transport? Active and passive transport are biological processes that move oxygen, water and nutrients into cells and remove waste products. Active transport requires chemical energy because it is the movement of biochemicals from areas of lower concentration to are...
Cellular Transport The lipid bilayer acts as a barrier to what kind of molecule from PCB 2099 at Florida International University
Short, helpful video on the topic of cellular transport by top AP US Biology teacher, Patrick. Videos are produced by leading online education provider, Brightstorm.
HYDROGEOCHEM 2 - reactive multispecies-multicomponent chemical transport model - hydrologic transport and mixed geochemical kinetic/equilbrium reactions in saturated/unsaturated media
Role of Lipids in the Regulation of Transport Processes across biological membranes. We aim for a holistic molecular description how specific lipids regulate transport of ions, nutrients and compatible solutes across cell membranes and between chemically distinct organelles. Diverse chemo-physical stimuli are involved the regulation of membrane channels and carriers; some of them linked to the adaptation to environment stress. Although these sensing and regulation mechanisms are very divers in all three kingdoms of life the common theme is an essential role of the lipids in stimuli perception and signal transduction. By solving atomic structures of individual transporters and channels in their native membrane environment and in complex with regulatory proteins in combination with functional measurements and spectroscopy we want to determine a molecular movie of lipid-mediated transport regulation.. ...
WP3. Cell biophysics and physiology (IBF): WP3 will be lead by IBF. This work package is focus in the biophysical and physiological characterization of the anionophores and the assessment of the physiological impact of the anionophore-induced anion transport on normal and cystic fibrosis bronchial cell models. Up to date very little is known about the fundamentals of transmembrane anion transport. WP3 will asses several aspects of anionophore activity which are crucial for further development of these compounds as drugs. Electrophysiological characterization of compounds will be obtained using voltage clamp in frog oocytes and patch clamp in mammalian cells. It includes a detailed functional analysis (transport efficiency, ionic composition dependence, pH dependence, temperature effects, voltage dependence), pharmacological analysis, and cell distribution of compounds by biochemical methods. Of particular relevance is the effect in the bronchial epithelial cell, which is among the most affected ...
The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cells ability to make the proteins necessary for essential biological functions. Until now, it ...
Scottish Transport Review 28 (PDF) Destination Transport - The Tourist as a User of Local Transport Can Scotlands Transport Cope with the Needs of Visitors? Travel to Sports Events - […]. ...
A system and computer program product for tracking and monitoring assets along a transport route. The system includes at least one receiver for receiving asset identifications transmitted from the as
Learn about shipping dangerous goods globally. Stay current on transport regulations affecting hazard classification, packaging, marking labeling and documentation.
The alkylating peptide PSF shows very promising results in vitro on different cancer cells but its efficacy in animals has not been assessed. Here we evaluate the efficacy of PSF in human melanoma-bearing nude mice and examine the underlying mechanis
Modes of Membrane Transport Transmembrane Transport movement of small substances through a cellular membrane (plasma, ER, mitochondrial..) ions, fatty acids, H 2 O, monosaccharides, steroids, amino acids
Pittsburgh, PA. Reduced models of flow or mass transport in heterogeneous media are often adopted in the computational approach when the geometrical configuration of the system at hand is too complex. A paradigmatic example in this respect is blood flow through a network of capillaries surrounded by a porous interstitium. We numerically address this biological system by a computational model based on a multiscale resolution of embedded domains. Exploiting their large aspect ratio, we avoid resolving the complex 3D geometry of the submerged vessels by representing them with a 1D geometrical description of their centerline and the resulting network [1,2].. Cancer employs mass transport as a fundamental mechanism of coordination and communication and the physics of mass transport within body compartments and across biological barriers differentiates cancer from healthy tissues [3]. Mass transport is also at the basis of cancer pharmacological treatment Delivery of diagnostic and therapeutic agents ...
Direct carrier transport measurements were performed for different InGaAsP/InGaAlAs MQW test structures. Shallow InGaAlAs barrier QW showed faster carrier transport. Semi-insulating regrown FP lasers with InGaAlAs barrier QW showed improved high temperature operation, modal gain, differential modal gain and chirp.. ...
Active Transport vs Passive Transport As minute as they are, cells in the body carry some very important processes deep within. These processes are all vital to
Predicted to have L-lysine transmembrane transporter activity; L-ornithine transmembrane transporter activity; and arginine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to localize to plasma membrane. Orthologous to human SLC7A2 (solute carrier family 7 member 2 ...
The driving forces for solute transport at the membrane level in plants are the same as those in other biological membrane systems. However, the presence of a cell wall and of a vacuole in plant...
Crash Course Biology: In Da Club - Membranes and Transport, by Hank Essential Biology 2.4: Membranes For lots more animations on cell structure and function and cell transport, visit North Harris College. You can also work through the Membranes lessons from HippoCampus Biology. ..........o0O0o.......... Membrane Structure: The Fluid Mosaic Model Fluid Mosaic Model Tutorial from…
Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. Several important examples of their role in drug disposition and drug-drug interactions have been described to date. Investigation of drug-drug interactions at the transport protein level are therefore of increasing interest to the academic, industrial and regulatory research communities.. The gene expression of transport proteins involved in drug transport was investigated in the jejunum, liver, kidney and colon to better understand their influence on the ADMET properties of drugs. In addition, the gene and protein expression of transport proteins in cell lines, widely used for predictions of drug transport and metabolism, was examined.. The substrate and inhibitor heterogeneity ...
Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. Several important examples of their role in drug disposition and drug-drug interactions have been described to date. Investigation of drug-drug interactions at the transport protein level are therefore of increasing interest to the academic, industrial and regulatory research communities.. The gene expression of transport proteins involved in drug transport was investigated in the jejunum, liver, kidney and colon to better understand their influence on the ADMET properties of drugs. In addition, the gene and protein expression of transport proteins in cell lines, widely used for predictions of drug transport and metabolism, was examined.. The substrate and inhibitor heterogeneity ...
1. The present study has determined the kinetics of the uptake of L-3,4-dihydroxyphenylalanine (L-DOPA) and 3-O-methyl-L-DOPA (3-OMDOPA) in rat renal tubules and examined the effect of 3-OMDOPA on the inward transport of L-DOPA and on its conversion into dopamine in kidney homogenates. 2. The accumulation of both L-DOPA and 3-OMDOPA in renal tubules was found to occur through non-saturable and saturable mechanisms. The kinetics of the saturable component of L-DOPA and 3-OMDOPA uptake in renal tubules were as follows: L-DOPA, Vmax = 11.1 nmol mg-1 protein h-1 and Km = 216 microM (n = 6); 3-OMDOPA, Vmax = 8.1 nmol mg-1 protein h-1 and Km = 231 microM (n = 5). The diffusion constant of the non-saturable component for the accumulation of L-DOPA and 3-OMDOPA was 0.0010 and 0.0014 mumol-1, respectively. 3. 3-OMDOPA (100 to 2000 microM) was found to produce a concentration-dependent decrease (29% to 81% reduction) of the saturable component of the tubular uptake of L-DOPA; the Ki value of 3-OMDOPA for
The transport properties for phenylalanine and glucose in luminal-membrane vesicles from outer cortex (pars convoluta) and outer medulla (pars recta) of rabbit kidney were studied by a spectrophotometric method. Uptake of phenylalanine as well as of glucose by the two types of membrane vesicles was found to be Na+-dependent, electrogenic and stereospecific. Na+-dependent transport of L-phenylalanine by outer-cortical membrane vesicles could be accounted for by one transport system (KA congruent to 1.5 mM). By contrast, in the outer-medullary preparation, L-phenylalanine transport occurred via two transport systems, namely a high-affinity system with K1A congruent to 0.33 mM and a low-affinity system with K2A congruent to 7 mM respectively. Na+-dependent uptake of D-glucose by pars convoluta and pars recta membrane vesicles could be described by single, but different, transport systems, namely a low-affinity system with KA congruent to 3.5 mM and a high-affinity system with KA congruent to 0.30 ...
This cell transport lab will give your students a hands-on and up-close view of osmosis, diffusion, and plasmolysis in living cells. This lab has two different activities. In the first part of this lab, the observation of plasmolysis in a living cell is a qualitative measurement.
metabolism definition process biology britannica cell transport flow chart worksheet acetyl coenzyme compound release molecule an the only solution across membrane
TY - JOUR. T1 - A new locus in the phosphate specific transport (PST) region of Escherichia coli. AU - Levitz, Ruth. AU - Klar, Avihou. AU - Sar, Nehemia. AU - Yagil, Ezra. PY - 1984/10/1. Y1 - 1984/10/1. N2 - PhoS64 is a mutation in the Phosphate Specific Transport (PST) region on the E. coli chromosome which lacks the periplasmic phosphate binding protein. In contrast to other phoS mutations (which have the same phenotype) it complements the mutations in phoT and pstB. A detailed genetic map of the PST region constructed by three point transductional crosses has revealed that phoS64 is located distally from other phoS mutations. The genetic order obtained was phoS64-phoU35-pstB401-phoT-phoS-ilvC. The data indicate that phoS64 belongs to a different complementation unit in the PST region not known hitherto. We propose to name it phoV.. AB - PhoS64 is a mutation in the Phosphate Specific Transport (PST) region on the E. coli chromosome which lacks the periplasmic phosphate binding protein. In ...
The camera lens diaphragm is an important component in a noncontact optical imaging system and has a crucial influence on the images registered on the CCD camera. However, this influence has not been taken into account in the existing free-space photon transport models. To model the photon transport process more accurately, a generalized free-space photon transport model is proposed. It combines Lambertian source theory with analysis of the influence of the camera lens diaphragm to simulate photon transport process in free space. In addition, the radiance theorem is also adopted to establish the energy relationship between the virtual detector and the CCD camera. The accuracy and feasibility of the proposed model is validated with a Monte-Carlo-based free-space photon transport model and physical phantom experiment. A comparison study with our previous hybrid radiosity-radiance theorem based model demonstrates the improvement performance and potential of the proposed model for simulating photon ...
It has been determined that cortisol and a few other steroids are transported outward from certain mammalian cells growing in vitro. The extrusion process is temperature dependent, glucose dependent, saturable, and operates for only a few selected steroids. Many, but not all, steroids are able to block the extrusion process but are not themselves transported. The outward transport process for steroids has been found in mouse fibroblasts, mouse lymphoma cells, and functional mouse adrenal gland tumor cells growing in vitro. The transport process is not present in two varieties of cells cultured from human sources-HeLa or diploid fibroblasts, WI-38.. ...
Intercellular transport of auxin is driven by PIN-formed (PIN) proteins. PINs are localized at the plasma membrane (PM) and on constitutively recycling endomembrane vesicles. Therefore, PINs can mediate auxin transport either by direct translocation across the PM or by pumping it into secretory vesicles (SVs), leading to its secretory release upon fusion with the PM. Which of these two mechanisms dominates is a matter of debate. Here we addressed the issue with a mathematical modeling approach. We demonstrate that the efficiency of secretory transport depends on SV size, half-life of PINs on the PM, pH, exocytosis frequency and PIN density. 3D-SIM microscopy was used to determine PIN density on the PM. Combing this data with published values of the other parameters, we show that the transport activity of PINs in SVs would have to be at least 1000x greater than on the PM in order to produce a comparable macroscopic auxin transport. If both transport mechanisms operated simultaneously and PINs were
Multi-particle non-equilibrium dynamics in two-channel biological transport systems is investigated theoretically within the framework of asymmetric simple exclusion processes (ASEP). In exclusion processes particles move along the lattice by hopping between neighboring sites that are vacant. We consider the systems with open boundaries, where particles enter the lattice on the entrance site and leave from the exit site with given rates. Four different ASEP models are studied. The first two models investigate interchannel coupling between parallel channels in a one-way transport system. The third model considers junction of two parallel tracks, while the last model investigates two-way transport system with narrow entrances with coupling on the boundaries. Theoretical investigation of these non-equilibrium systems reveal many interesting phenomena, such as unusual phase diagrams that contain up to seven stationary-state phases, localization of the domain wall in the bulk of the system, ...
Transportation can be very stressful for animals due to rough handling, extreme weather and long transport times. Get involved in changing transport laws!
Endothelial cells separate the bloodstream from the underlying tissue and play a crucial role in vascular homeostasis. They also form an important barrier for vascular drug delivery. This thesis contains preliminary studies targeted at understanding the mechanisms of binding and transport across endothelial cells cultured in vitro. Specifically, the first study investigates how the recombinant source of Factor IX (FIX), a blood coagulant protein used in the treatment of Hemophilia B, impacts surface ligand binding (FIX to its specific receptors) to bovine aortic endothelial cells (BAECs). Competitive binding experiments between 125I-FIX and FIX were undertaken to quantify the interaction of recombinant and transgenic FIX with BAECs and human collagen IV and determine if there was a measurable difference in binding affinity. Results indicate limited specific binding of 125I-FIX to BAECs and no binding to human collagen IV. Concrete conclusions were not drawn from this data due to technical issues ...
Inborn Amino Acid Transport Disorders: Disorders characterized by defective transport of amino acids across cell membranes. These include deficits in transport across brush-border epithelial cell membranes of the small intestine (MICROVILLI) and KIDNEY TUBULES; transport across the basolateral membrane; and transport across the membranes of intracellular organelles. (From Nippon Rinsho 1992 Jul;50(7):1587-92)
The SapNP technology allows scientists to work in a detergent free environment however; detergents were initially used to extract the proteins from the membrane. Ideally we would like to eliminate the use of detergents entirely, explains Löw. These developments are ongoing and will allow us to study membrane proteins that cannot be extracted with detergents in the future. Furthermore, the SapNP method is beneficial for studying the structure of membrane proteins by single particle electron cryo-microscopy which avoids the tedious step of growing crystals. The combination of both methods at the CSSBs cryo-EM facility will provide new structural and functional information about membrane proteins such as the human PepT1 and PepT2 transporters, which transport drugs into human cells ...
Biological transport is a key step of your quality process-the integrity of previous sampling phases and/or later analysis phases depends on it. (...)
In order to verify the research from this laboratory that sheep omasal epithelium contains mRNA encoding for a peptide transporter (s) and to determine di- to octapeptide transport capability, poly(A)+ RNA isolated from sheep omasal epithelium was injected into Xenopus laevis oocytes. Poly(A)+ RNA was functionally expressed in Xenopus oocytes 4 to 7 d post-injection. Peptide (5 di-, 10 tri-, 6 tetra-, 2 penta-, 1 hepta-, 1 septa-, 1 octapeptide) transport capability was measured by impaling oocytes with a microelectrode to monitor membrane potential (Vm). Oocytes were maintained in pH 5.5 buffer. Peptide transport was identified as being expressed when, in the presence of a buffered peptide substrate (1 mM), the oocyte membrane showed persistent depolarization (a more positive Vm). In the absence of peptide transport, the membrane became depolarized with the addition of buffered substrate, but rapidly repolarized to the resting potential. Peptide transport was expressed for some di-, tri-, and ...
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth.
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth.
The hypothesis tested was that ketoconazole can modulate P-glycoprotein, thereby altering cellular uptake and apparent permeability (P(app)) of multidrug-resistant substrates, such as cyclosporin A (CSA) and digoxin, across Caco-2, MDCKII-MDR1, and MDCKII wild-type cell transport models. (3)H-CSA/(3)H-digoxin transport experiments were performed with and without co-exposure to ketoconazole, and (3)H-ketoconzole transport ...
Announcement: Quiz on Homeostasis and Cell Transport will be next week Monday 5/18, testing window will be from 1-5 pm Mon 5/11 Watch Active Transport Lecture Recording Warm-up and Post Lecture discussion question Tues Passive and Active Transport 5.1 & 5.2 section review questions Diffusion Demo and Lab Questions. Wed Cell Homeostasis Virtual Lab Thurs Ch 5 Understanding Key Concept and STP Fri Homeostasis and Cell Transport Quizlet Practice. Note: All listed assignments were initially due by Fridays 5/15 at 2pm, but assignment extension was provided due to AP Exam on Friday. Next Deadline: Monday 5/18 Warm up and Post lecture questions Ch 5.1 and 5.2 section review questions Cell Homeostasis Virtual Lab Ch 5 Understanding Key Concept and STP Screenshot of Ch 5 Quizlet Practice test result. ...
Specific membrane transporters mediate the passage of a wide variety of substances across cellular membranes. Classes of substrates include amino acids, sugars, cations, anions, vitamins, and water. The number of inherited disorders of membrane transport continues to increase with the identification of new transporters on the plasma membrane or intracellular organelles and the clarification of the molecular basis of diseases with previously unknown pathophysiology. The first transport disorders identified affected the gut or the kidney, but transport processes are now proving essential for the normal function of every organ. Mutations in transporter molecules cause disorders of the heart, muscle, brain, and endocrine and sensory organs (Table 435e-1). Inherited defects impairing the transport of selected amino acids that can present in adults are discussed here as examples of the abnormalities encountered; others are considered elsewhere in this text. ...
We present a numerical study of collisional transport in a tokamak pedestal in the presence of non-trace impurities, using the radially global delta-f neoclassical solver PERFECT [M. Landreman et al. 2014 Plasma Phys. Control. Fusion 56 045005]. It is known that in a tokamak core with non-trace impurities present the radial impurity flux opposes the bulk ion flux to provide an ambipolar particle transport, with the electron transport being negligibly small. However, in a sharp density pedestal with sub-sonic ion flows the electron transport can be comparable to the ion and impurity flows. Furthermore, the neoclassical particle transport is not intrinsically ambipolar, and the non-ambipolarity of the fluxes extends outside the pedestal region by the radial coupling of the perturbations. The neoclassical momentum transport, which is finite in the presence of ion orbit-width scale profile variations, is significantly enhanced when impurities are present in non-trace quantities, even if the total parallel
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Some examples of active transport are endocytosis, exocytosis and the use of a cell membrane pump; diffusion, osmosis and facilitated diffusion are all examples of passive transport. In active transport, particles move from areas of low concentration to high concentration, while in passive transport, the particles move from areas of high concentration to areas of low concentration.. ...
membrane, glucose transmembrane transporter activity, substrate-specific transmembrane transporter activity, sugar:proton symporter activity, glucose import, hexose transmembrane transport, transmembrane transport
TY - CHAP. T1 - Drug transporters. AU - Penzak, Scott Robert. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Membrane transporters are present in a variety of anatomical locations and organ systems throughout the body. Transporters control the absorption, distribution, intracellular penetration, and excretion of numerous drugs. ATP-binding cassette (ABC) and solute carrier (SLC) superfamilies comprise the majority of clinically relevant transport proteins. In intestinal and liver epithelia, transport proteins control the access of certain medications to systemic circulation. In the kidney, transporters may facilitate or impair drug excretion depending on their specific location and function. However, it is at the blood-brain barrier (BBB) where membrane transporters regulate access of endogenous and exogenous compounds to the central nervous system (CNS). This chapter will review the common drug transport proteins in the intestine and liver as they impact the systemic exposure of drugs that exert their ...
Cancer is an extraordinarily complex disease. It is now recognized that methods commonly used in physics can help reducing the complexity of cancer to a manageable set of underlying principles and phenomena [1, 2]. Physical properties of biological barriers control cell, particle, and molecule transport across tissues and this transport and its deregulation play an overarching role in cancer physics. According to [1], tissue invasion is mass transport deregulation at the interface between the cell and the microenvironment; metastasis is a deregulation of local and distant cellular transport at the scale of the organism; tumor-associated angiogenesis completely alters mass and fluid exchange across the microcirculation; alterations in the signaling pathways that accompany the evasion of apoptosis, growth signal dependence and growth inhibitory messages from the immediate environment are also disruptions in molecular transport since molecular signaling depends directly on the transport of ...
Nutrition All living organisms requires energy. They take in nutrition to produce energy, to grow and repair.. Below is an illustration which shows simple diffusion. Simple diffusion is when molecules travel from a place which has a lot of molecules to a place that either lacks or has low amounts of molecules. They do this by travelling down through the membrane until both places have, more or less equal amounts of molecules. Molecules that travel through the simple diffusion method must be nonpolar and they must be small in size. Below is an illustration which shows facilitated diffusion. Facilitated diffusion is different to simple diffusion because the molecules can not travel directly through the membrane. In order to go from a place which has lots of molecules to a place which lacks or doesnt have many molecule, it needs to use a channel. This channel is named a protein channel and it provides the molecules a way of getting through to the membrane.. Below is an illustration that shows ...
Just to extend the answer from @Amory slightly, I think that the terms active and passive transport are best kept for describing transmembrane movement of molecules. In the case of exocytosis the only transmembrane event is when a secreted protein is first inserted (usually cotranslationally) across the endoplasmic reticulum membrane. Im not aware of any evidence that this uses more energy than that already expended during polpeptide elongation by the ribosome. At that point the secreted protein is topologically extracytoplasmic, and everything else is achieved by rounds of vesicle formation and fusion of vesicles with target membranes. The same is true in reverse for endocytosis. Any molecule that is internalised in an endocytic vesicle is still extracytoplasmic unless some process specifically moves it across the membrane of the vesicle, or a downstream organelle such as the endosome. At that point whether the transport process was active or passive would depend upon the properties of the ...
Nitric oxide (NO) is a key endothelial cell (EC) signaling molecule that exerts its actions both within the EC and within heterologous target cells. Most investigators have assumed that NO traverses the plasma membrane of the EC by simple diffusion owing to its relative lipophilicity; however, the possibility of transmembrane channel-dependent transport has not been explored in any detail. In this study, we used bovine aortic ECs to test whether the water channel, aquaporin 1 (AQP1), and glucose transporters, could promote NO efflux from and influx into the EC. We measured NO efflux by activating EC NO synthase with 3 uM A23187, and assaying L-NAME-inhibited NO released into the media by nitrite/nitrate determination. We measured NO influx by incubating ECs with DPTA NONOate after loading the cells with the NO-sensitive intracellular fluorophore, DAF-FM. Using Western blot analysis, AQP1 mRNA was detected by quantitative RT-PCR (in human ECs), but protein expression was only detected with ...
In this study, particle transport and captured behaviors in a Diesel Particulate Filter (DPF) was investigated with Lattice Boltzmann Method. LBM calculation was performed to a 3D-reconstructed micro porous DPF substrate, which was obtained by micro-focus 3D X-ray technique. Simulating advection-diffusion behaviors of diesel particulates in micro porous channel, we adapted a LBM method used for high Peclet number flow, simulating flow conditions in DPFs. We investigated flow behaviors in a wide variety of inlet velocity. LBM simulation has clearly shown that non-dimensional flow field is similar in wide range of flow conditions in the DPF, because flow Reynolds number in the micro porous substrate is sufficiently low, dominated by laminar flow regime. It was also revealed that less than 40% pore channels was responsible for more than 80% volume flux in the porous substrate without particle loading. We also examined particle deposition behaviors in the porous substrate with LBM simulation. It was ...
Stochastic and continuum dynamics in cellular transport. SIAM Minisymposium on Mathematical modeling and simulation of complex biological systems. Joint Mathematics Meetings. January 2020
Protein aggregation can be a critical problem leading to human pathologies such as Alzheimers or Parkinsons disease.. Mitochondria, the compartments that produce most of the cellular energy, contain surface receptors, which facilitate protein uptake. These receptors specifically recognize mitochondrial proteins and direct them through pores into the interior of mitochondria, explains Prof. Johannes Herrmann, a specialist for mitochondrial biology. But, so far, we had no idea what these proteins encounter before they reach the mitochondrial surface. It was just assumed that newly synthesized proteins are directly targeted to their destination compartment.. In a close collaboration with Professor Maya Schuldiner from the Weizmann Institute in Rehovot, Israel, Herrmanns team observed that mitochondrial proteins are initially targeted to the surface of the endoplasmic reticulum (ER). The ER is a cellular compartment that serves as a central sorting station to deliver proteins to various ...
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One of the most common investigation techniques of type-II superconductors is the transport measurement, in which an electrical current is applied to a sample and the corresponding resistance is measured as a function of temperature and magnetic field. At temperatures well below the critical temperature, Tc, the resistance of a superconductor is usually immeasurably low. But at elevated temperatures and fields, in the so-called vortex liquid phase, a substantial linear resistance is observed1. In this dissipative state, which in anisotropic high-temperature superconductors like Bi2Sr2CaCu2O8 may occupy most of the mixed-state phase diagram, the transport current is usually assumed to flow uniformly across the sample as in a normal metal. To test this assumption, we have devised a measurement approach which allows determination of the flow pattern of the transport current across the sample. The surprising result is that, in Bi2Sr2CaCu2O8 crystals, most of the current flows at the edges of the sample
Such requirements resulted, first, in the evolutionary appearance of more constrained channels that could assume carrier functions, secondly, in the appearance of larger, more complex obligatory secondary carriers that could no longer catalyse passive diffusion and, thirdly, in the emergence of primary active transporters and group translocators with superimposed energy-coupling subunits. Thus, the ancestral precursors of all these transporter types were simple peptide channels. The pathways most frequently taken were evidently tandem intragenic duplications giving rise to larger helical bundles that had the potential to form discrete stereospecific intramembranous substrate binding sites. They could also be constrained for coupling to other transport processes and, through conformational coupling, they were subject to control by a superimposed primary energy-yielding process such as ATP hydrolysis. We assume that none of these requirements could be satisfied by the ancestral one, two or three ...
Such requirements resulted, first, in the evolutionary appearance of more constrained channels that could assume carrier functions, secondly, in the appearance of larger, more complex obligatory secondary carriers that could no longer catalyse passive diffusion and, thirdly, in the emergence of primary active transporters and group translocators with superimposed energy-coupling subunits. Thus, the ancestral precursors of all these transporter types were simple peptide channels. The pathways most frequently taken were evidently tandem intragenic duplications giving rise to larger helical bundles that had the potential to form discrete stereospecific intramembranous substrate binding sites. They could also be constrained for coupling to other transport processes and, through conformational coupling, they were subject to control by a superimposed primary energy-yielding process such as ATP hydrolysis. We assume that none of these requirements could be satisfied by the ancestral one, two or three ...
Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
Four sets of nonreactive solute transport experiments were conducted with micromodels. Each set consisted of three experiments with one variable, i.e., flow velocity, grain diameter, pore-aspect ratio
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (Glut or SLC2A family / solute carrier…
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Description: The transport regulations have changed with an aim to facilitate the transport of certain biological materials. What is new? Are these new regulations really clearer and easier to use? What are the problems? Are there country differences and why? Come and share your experiences and questions and lets see if we can agree on common solutions to unclear situations.. Discussion Group 2: European biosafety: a common approach? ...
The transport regulations applicable to lithium batteries can be difficult to navigate for companies and individuals who are not familiar with dangerous goods in general. As there are different parties involved in the transport of lithium batteries from manufacturers, technicians and engineers to battery assemblers and consumer electronics retailers, IATA has created the LBSG to … Continue reading ». ...
Neutral molecules transported by a Porin channelsb Ionophoresc Simple diffusion Absence of charge over molecules (Uncharged/Neutral molecules) favours their transport by simple diffusion. Small neutral molecules are usually transported freely across plasma membranes by simple dif
TY - JOUR. T1 - A new approach to the study of ion transport processes by an in situ radiotracer method based on measuring intensity changes and energy spectrum alterations of β-radiation. AU - Németh, Z.. AU - Erdei, L.. AU - Kolics, A.. PY - 1995/3. Y1 - 1995/3. N2 - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the penetration of labeled species. The applicability of the radiotracer technique is detailed through the measurement of the transport of labeled chloride ions into a PERMAPLEX-A20 anion exchanger membrane. The proposed method is applicable to in situ monitoring of the motion of ions in the membrane (or adsorbent).. AB - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the ...
NEW March 2013. 60 pages fitted two to an A4 view. London Transport Regulations concerning the supply and switching of traction current. At the back is a diagrammatic map indicating the sections for the supply. May 1982.. This file will be available to download as soon as payment has been made. You go to your account and click on Downloads. New customers create an account as they place their order.. ? ...
Convection motions within the Sun transport heat from its interior to its surface. The hot regions are seen as granular (∼1000 kilometers across) and supergranular (∼30,000 kilometers across) cells in the Sun. Using data from the Helioseismic Magnetic Imager on the Solar Dynamics Observatory, Hathaway et al. (p. 1217) found evidence for even larger cells that have long been predicted by theory but not unambiguously detected. The flows associated with these giant cells transport angular momentum toward the equator and are important for maintaining the Suns equatorial rotation.. Video follows: GO WITH THE FLOW Long-lasting plasma flows appear in red and blue in this animation, which portrays data from four solar rotations. Some flows persist for several months; these patterns are especially visible near the suns north pole. Scientists think these flows keep the suns equator rotating faster than its poles.. ...
Ground-based remote sensing observations from Aerosol Robotic Network (AERONET) sun-sky radiometers have recently shown several instances where cloud-aerosol interaction had resulted in modification of aerosol properties and/or in difficulty identifying some major pollution transport events due to aerosols being imbedded in cloud systems. Major Distributed Regional Aerosol Gridded Observation Networks (DRAGON) field campaigns involving multiple AERONET sites in Japan and South Korea during Spring of 2012 have yielded observations of aerosol transport associated with clouds and/or aerosol properties modification as a result of fog interaction. Analysis of data from the Korean and Japan DRAGON campaigns shows that major fine-mode aerosol transport events are sometimes associated with extensive cloud cover and that cloud-screening of observations often filter out significant pollution aerosol transport events. The Spectral De-convolution Algorithm (SDA) algorithm was utilized to isolate and analyze ...
Mohammad, H#., Marchisella, F#., Ortega-Martinez, S.#,Hollos, P., Eerola, K., Komulainen, E., Kulesskaya, N.Freemantle, E., Fagerholm, V., Savbontaus, E., Rauvala, H., Peterson, B.D., van Praag, H., Coffey, E. JNK1 controls adult hippocampal neurogenesis and imposes cell autonomous control of anxiety behaviour from the neurogenic niche. Molecular Psychiatry. 2016, In press. #equal contribution. Marchisella, F., Coffey, E.T. *, Hollos, P. Microtubule and microtubule associated protein anomalies in psychiatric disorders. Cytoskeleton. Special review issue on Emerging Concepts in Neuronal Cytoskeleton. 2016 in press. Padzik, A#, Deshpande, P#, Hollos, P#, Franker, M, Rannikko, E, Cai, D, Prus, P, Mågard, M, Westerlund, N, Verhey, K, James, P, Hoogenraad, C, Coffey, ET. KIF5C S176 phosphorylation regulates microtubule binding and transport efficiency in neurons. Frontiers in Cellular Neuroscience. 2016 in press. #equal contribution. Varidaki, A, Mohammad, H, Coffey, ET. Molecular Mechanisms of ...
Photon transport in biological tissue can be equivalently modeled numerically with Monte Carlo simulations or analytically by ... Thus, over one transport mean free path, the fractional change in current density is much less than unity. This property is ... Convert the pencil beam into an isotropic point source at a depth of one transport mean free path l {\displaystyle l} ' below ... Yoo, K. M.; Liu, Feng; Alfano, R. R. (1990-05-28). "When does the diffusion approximation fail to describe photon transport in ...
... sustainable transport; climate change and disaster risk reduction; oceans and seas; forests; vulnerable groups including ... "International Day for Biological Diversity - 22 May". Convention on Biological Diversity. Archived from the original on May 19 ... The International Day for Biological Diversity (or World Biodiversity Day) is a United Nations-sanctioned international day for ... The International Day for Biological Diversity falls within the scope of the UN Post-2015 Development Agenda's Sustainable ...
The AIT could transport two patients simultaneously; obviously, this was not designed for a mass casualty situation. During the ... The U.S. biological defense program began as a small defensive effort that parallels the country's offensive biological weapons ... In recent years certain critics have claimed the U.S. stance on biological warfare and the use of biological agents has ... In the 1990s, the US medical biological defense research effort (part of the U.S. Army's Biological Defense Research Program [ ...
Salomon, Etian; Keren, Nir (2011). "Manganese in Biological systems: Transport and Function". Patai's Chemistry of Functional ... 2002). Metal ions in biological systems: molybdenum and tungsten: their roles in biological processes. Vol. 39. Taylor & ... The redox transformation of Fe(II) to Fe(III), or vice versa, is vital to a number of biological and element cycling processes ... Metal ion binding to such O-donors was required to build the biological polymers, since the bond is generally weak, it can ...
... is the anisotropy of biological tissue, which has a representative value of 0.9. Figure 5 shows a plot of transport scattering ... Light scattering in biological tissue is denoted by the scattering coefficient ( μ s {\displaystyle \mu _{s}} ), which is ... Melanin is one of the major absorbers of light in some biological tissue (although its contribution is smaller than other ... Oxygen Transport to Tissue XXVI 566, 17-22, 2006. (Articles with short description, Short description matches Wikidata, ...
... and extra-cellular electron transport by cyanobacteria". Biochemical Society Transactions. 40 (6): 1302-1307. doi:10.1042/ ... Biological photovoltaic devices are a type of biological electrochemical system, or microbial fuel cell, and are sometimes also ... biological photovoltaic systems which employ whole organisms have the advantage over non-biological fuel cells and photovoltaic ... Biological photovoltaic systems are defined by the type of light harvesting material that they employ, and the mode of electron ...
There are different types of transport such as bus, van etc. Each has one amount. KSTDC focuses on sales, revenue collection ... The bifurcation of the Biological Park and the National Park took place in 2002. The Bannerghatta Biological Park covers a ... In 2007, a Butterfly Park was established within the limits of the Biological Park. The Bannerghatta Biological Park is located ... "Bengaluru Bannerghatta Biological Park: Animal Adoption". Bannerghatta Biological park Annual Report 2020-2021 : Objectives. p ...
Lein, Max; deRonde, Brittany M.; Sgolastra, Federica; Tew, Gregory N.; Holden, Matthew A. (2015-11-01). "Protein transport ... If biological membranes were not fluid, it is hard to imagine how cells could live, grow, and reproduce. Collodion bag Fluid ... A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell ... Biological membranes also have certain mechanical or elastic properties that allow them to change shape and move as required. ...
After transport of an infected patient is completed, Phoenix Air performs a decontamination process stipulated by the CDC. This ... The Aeromedical Biological Containment System (ABCS) is an aeromedical evacuation capability devised by the U.S. Centers for ... Its purpose is to safely air-transport a highly contagious patient; it comprises a transit isolator (a tent-like plastic ... Kent Brantly, an employee of Samaritan's Purse) ever to be evacuated to the United States; three days later, it transported ...
Sea water transport organisms, which facilitates the food capture and fertilization. Many settled bottom organisms use their ...
... presumably from the transported pathogens. In the 2000s, the academician, "A.S.", proposed a new biological warfare program, ... Boris Yeltsin admitted to an offensive biological weapons program as well as to the true nature of the Sverdlovsk biological ... 1998 Post-World War II Programs of Biological Weapons The Russian Biological Weapons Program: Vanished or Disappeared? by Dany ... the dismantlement of experimental technological lines for the production of biological agents and the closure of biological ...
... biological diversity (implementation of the UN Convention on Biological Diversity); Urban and industrial environmental ... Transport and infrastructure: transport policy and infrastructure management; sustainable urban mobility; Security, ... biological diversity; Sustainable Infrastructure: Water: in the field of water, sub-topics include sustainable sanitation and ...
"Transport in Plants". Department of Biological Sciences, University of Illinois at Chicago. Archived from the original on 12 ... Transport velocity is higher (transport is faster) in the apoplast than in the symplast. This method of transport also accounts ... The apoplastic pathway is one of the two main pathways for water transport in plants, the other being symplastic pathway. In ... The apoplastic route is one way by which water and solutes are transported and distributed to different places through tissues ...
Le Moigne FA (2019). "Pathways of Organic Carbon Downward Transport by the Oceanic Biological Carbon Pump". Frontiers in Marine ... Raven JA (1983). "The Transport and Function of Silicon in Plants". Biological Reviews. 58 (2): 179-207. doi:10.1111/j.1469- ... Biological mineralization can also take place as a result of fossilization. See also calcification. Among animals, biominerals ... Biological materials are assembled in aqueous environments under mild conditions by using macromolecules. Organic ...
Biological Psychiatry. 77 (6): 526-36. doi:10.1016/j.biopsych.2014.07.017. hdl:11858/00-001M-0000-0025-7742-E. PMID 25176177. ... a putative organic anion transport protein". World Journal of Gastroenterology. 12 (42): 6797-805. doi:10.3748/wjg.v12.i42.6797 ...
Drake, J.A., Mooney, H.A., Castri, F.di., Groves, R.H., Kruger, F.J., Rejmánek, M. and Williamson, M. (1989). Biological ... doi:10.1016/0006-3207(96)00020-1. Cariton, J. T.; Geller, J. B. (1993). "Ecological Roulette: the Global Transport of ... ISBN 0-471-92085-1 Carlton, J (1996). "Pattern, process, and prediction in marine invasion ecology". Biological Conservation. ...
Macro-invertebrates are transported by transoceanic and coastal vessels arriving in ports all over the world. Researchers from ... Biological Invasions. Springer. 14 (9): 1843-1850. doi:10.1007/s10530-012-0194-0. ISSN 1573-1464. S2CID 14502375. First, ... Briski, E.; Ghabooli, S.; Bailey, S.; MacIsaac, H. (2012). "Invasion risk posed by macroinvertebrates transported in ships' ... and procedures reduce the density and richness of biota effectively in ballast waters and thus reduce the risk of transporting ...
Hulme, Philip E. (2009). "Trade, transport and trouble: managing invasive species pathways in an era of globalization". Journal ... Oxford University Press (American Institute of Biological Sciences). 60 (11): 886-897. doi:10.1525/bio.2010.60.11.5. ISSN 1525- ... Biological Invasions. Springer. 8 (4): 611-630. doi:10.1007/s10530-005-1798-4. S2CID 23684940. • ...
"Transport". Taman Negara. 21 February 2017. 10. ↑ KL to Taman Negara shuttle service Wikimedia Commons has media related to ... There are several geological and biological attractions in the park. Gunung Tahan is the highest point of the Malay Peninsula; ... Biological Conservation. 120 (3): 329-344. doi:10.1016/j.biocon.2004.03.005.{{cite journal}}: CS1 maint: multiple names: ...
Seed dispersal is the movement or transport of seeds away from the parent plant. Plants are limited by vegetative reproduction ... Biological dispersal refers to both the movement of individuals (animals, plants, fungi, bacteria, etc.) from their birth site ... Therefore, biological dispersal is critical to the stability of ecosystems. Few species are ever evenly or randomly distributed ... Biological dispersal may be contrasted with geodispersal, which is the mixing of previously isolated populations (or whole ...
Molecular Recognition in Biological Systems: Phosphate Esters vs Sulfate Esters and the Mechanism of Action of Steroid ... Quercetin 3-O-sulfate Pang, K; Schwab, A; Goresky, C; Chiba, M (1994). "Transport, binding, and metabolism of sulfate ... conjugates in the liver". Chemico-Biological Interactions. 92 (1-3): 179-207. doi:10.1016/0009-2797(94)90063-9. PMID 8033253. M ... Transport proteins, All stub articles, Biochemistry stubs). ...
On the air transport of the RF; Air techniques and the objects of civil aviation; Space craft; For nuclear sets, the points of ... storing radioactive materials; Means of protecting the information that include the state secret; Immune biological ... On the federal Railway transport; Means of protection of information; Security of manufacturing of explosives; In the sphere of ... The system of certification of mechanic transport means and trailers; The system of certification of gases; The "SEPROCHIM" ...
Evidence of Significant Transport of Coral and Symbiont Cells". The Biological Bulletin. 194 (2): 178-86. doi:10.2307/1543048. ... The larvae often need a biological cue to induce settlement such as specific crustose coralline algae species or microbial ... The Biological Bulletin. 201 (3): 360-73. doi:10.2307/1543614. JSTOR 1543614. PMID 11751248. S2CID 7765487. Archived from the ...
Lastly, various molecular biology studies have utilized D. etheria to both study foreign particle transport in sponges and to ... The Biological Bulletin. 170 (2): 321-334. doi:10.2307/1541812. ISSN 0006-3185. JSTOR 1541812. De Laubenfels, Max Walker (1936 ... D. etheria has also been utilized in research to understand how sponges transport foreign particles to specific locations ... Mesohyl cells have been observed to migrate in a coordinated fashion that allows for organized transport of particles. ...
Category B, UN 3373 - Biological substance transported for diagnostic or investigative purposes. Regulated Medical Waste, UN ... A biological hazard, or biohazard, is a biological substance that poses a threat to the health of living organisms, primarily ... "Biological hazards related to working alone safety", an article focusing on working alone safety when dealing with biological ... Level of the biocontainment precautions required to isolate dangerous biological agents Chemical hazard - Non-biological ...
Series B, Biological Sciences. 357 (1422): 737-47. doi:10.1098/rstb.2002.1091. PMC 1692983. PMID 12079669. Smith RS (December ... 2008). "The role of auxin transport in plant patterning mechanisms". PLOS Biology. 6 (12): e323. doi:10.1371/journal.pbio. ... ISBN 978-0-7679-0816-0. Snow, M.; Snow, R. (1934). "The interpretation of Phyllotaxis". Biological Reviews. 9 (1): 132-137. doi ...
She serves as an Editorial board member to scientific journals including Journal of Biological Chemistry, Molecular Biosystems ... "Molecular cooperation in mannose 6-phosphate receptor transport in SearchWorks catalog". searchworks.stanford.edu. Retrieved ... Journal of Biological Chemistry. 288 (37): 26480-26488. doi:10.1074/jbc.R113.467738. ISSN 0021-9258. PMC 3772195. PMID 23861405 ...
Drug transport and drug distribution in model systems and in biological systems". Arzneimittel-Forschung. 29 (8): 1067-80. PMID ... a process known as transcellular transport). For efficient transport, the drug must be hydrophobic enough to partition into the ... In areas such as drug discovery-areas involving partition phenomena in biological systems such as the human body-the log D at ... 2012). "Transport, Accumulation and Transformation Processes (Ch. 3), Properties of Chemicals and Estimation Methodologies (Ch ...
Cousins, Robert J.; Liuzzi, Juan P.; Lichten, Louis A. (2006). "Mammalian Zinc Transport, Trafficking, and Signals". Journal of ... and was involved in governance of biological sciences. In 1982, Cousins accepted an offer from the University of Florida (UF) ... Cousins, R. J. (1985). "Absorption, transport, and hepatic metabolism of copper and zinc: Special reference to metallothionein ... identifying tissue specificity and physiologic stimuli as regulators of zinc transport. Heavy emphasis was placed on ...
Series B, Biological Sciences. 367 (1592): 1112-22. doi:10.1098/rstb.2011.0206. PMC 3297437. PMID 22411982. Geibel S, Procko E ... Hultgren SJ, Baker D, Waksman G (April 2013). "Structural and energetic basis of folded-protein transport by the FimD usher". ... and head of the Department of Biological Sciences at Birkbeck. Waksman's laboratory studies the structures and mechanisms of ...
"sulfide(2−) (CHEBI:15138)". Chemical Entities of Biological Interest (ChEBI). UK: European Bioinformatics Institute. "SULFIDE ... pipelines transporting soured oil, Kraft paper factories. Microbially-induced corrosion (MIC) or biogenic sulfide corrosion are ...
Bencala, Kenneth E.; Walters, Roy A. (1983). "Simulation of solute transport in a mountain pool-and-riffle stream: A transient ... However, the hyporheic zone is a zone of biological and physical activity, and therefore has functional significance for stream ... Moreover, it exhibits a significant control on the transport of pollutants across the river basin. The main factors affecting ... Researchers use tools such as wells and piezometers, conservative and reactive tracers, and transport models that account for ...
Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport ... and biological rhythms. Test subjects included the crew, Japanese koi fish (carp), cultured animal and plant cells, chicken ...
In February 2016, the elder Bundy was transported back from Portland, Oregon, to Las Vegas, Nevada, to be tried in the United ... Kieran Suckling, executive director of the Center for Biological Diversity, called the suit a "bizarre, incoherent, yet ... the Center for Biological Diversity and multiple unnamed officers. The lawsuit seeks more than $5 million in damages for ...
In 1933, biological and geographical divisions were opened, which were later reorganized as Biology and Chemistry and Geography ... small business management and auto transport. Since January 2016 the name has been changed to Faculty of Engineering Education ...
He also stated that he found it "unacceptable" for biological parents to have the same status as legal guardians and social ... Dzhambazki took a vocally strong stance against the 2019 proposed changes[clarification needed] to the EU transport law ... after he dubbed transport committee chairwoman Karima Delli a "French woman from Algerian descent" and another one of the ... as the reforms were deemed to hurt Bulgarian transport companies. On 17 December 2019, a statement he published online against ...
From Adams' view, the technology that enables him to transcend the biological limitations of his frail body taps into a ... as his mind was transported into a computer simulation created by the Isu known as "The Grey". During his time there, he forgot ...
The Journal of Biological Chemistry. 265 (18): 10373-82. doi:10.1016/S0021-9258(18)86956-3. PMID 2355006. Pal R, Hoke GM, ... effects of monensin on glycosylation and transport". Journal of Virology. 63 (6): 2452-6. doi:10.1128/jvi.63.6.2452-2456.1989. ...
Kang, L., Shen, Z. & Jin, C. Neodymium cations Nd3+ were transported to the interior of Euglena gracilis 277. Chin.Sci.Bull. 45 ... Neodymium is otherwise not known to have a biological role in any other organisms. Neodymium metal dust is combustible and ...
Jesse Metcalfe as Christopher Ewing, the adopted son of Bobby and his ex-wife Pamela Barnes Ewing and the biological son of Sue ... It is revealed during the season 2 finale that Ryland's transport company is also a front for cocaine smuggling where the ... Mitch Pileggi as Harris Ryland (seasons 2-3, recurring previously), the head of Ryland Transport and Ann's ex-husband. Ruthless ...
... which drives proton transport. The proton gradient formed thereby can then be used to generate chemical energy via ATP synthase ... The Journal of Biological Chemistry. 251 (7): 2005-14. doi:10.1016/S0021-9258(17)33647-5. PMID 1270419. Sára, M; Sleytr, U. B ...
Comparatively, the astral influences on the macrocosmal Spirit could be transported to the microcosmal Spirit in the blood by ... ISBN 978-1-55643-373-3. Walter Pagel (1967). William Harvey's Biological Ideas: Selected Aspects and Historical Background. ...
The connectivity of Bhutan increased in his reign through air services, internet, and surface transport. Internet reached ... and Bomdeling Wildlife Sanctuary established in 1993 UN Framework Convention on Climate Change and Convention on Biological ...
Carbohydrates are the most abundant biological molecules, and fill numerous roles, such as the storage and transport of energy ... "Mammalian zinc transport, trafficking, and signals". The Journal of Biological Chemistry. 281 (34): 24085-9. doi:10.1074/jbc. ... This is done in eukaryotes by a series of proteins in the membranes of mitochondria called the electron transport chain. In ... Series B, Biological Sciences. 293 (1063): 5-22. Bibcode:1981RSPTB.293....5B. doi:10.1098/rstb.1981.0056. PMID 6115423. Pilkis ...
Hung Chung-chiu was raised in Taichung City by his biological uncle. He lived with his adoptive parents and older sister, Hung ... Similar questions were raised on delays in emergency transport and treatment of Hung after he fell into coma at the detention ...
Schrader F (1921). "The chromosomes in Pseudococcus nipæ". Biological Bulletin. 40 (5): 259-270. doi:10.2307/1536736. JSTOR ... as genomic imprinting was thought to be associated with the evolution of viviparity and placental nutrient transport. Studies ... Biological Sciences. 264 (1388): 1657-62. Bibcode:1997RSPSB.264.1657H. doi:10.1098/rspb.1997.0230. PMC 1688715. PMID 9404029. ...
Higher substrate concentrations are usually caused by osmotic issues, viscosity, or inefficient oxygen transport. By slowly ... "Overcoming substrate inhibition during biological treatment of monoaromatics: recent advances in bioprocess design". Applied ... or inefficient oxygen transport due to overly concentrated substrate in the bioreactor medium. Substrates that are known to ...
The privately funded Computational Sciences Facility and Biological Sciences Facility house about 310 staff who support PNNL's ... and subsurface flow and transport. The Bioproducts, Sciences, and Engineering Laboratory (BSEL) is a joint effort between ... APEL provides engineering- and manufacturing-scale space and chemical, biological, and electronic laboratories and equipment ...
This should be considered for choosing a non-metallic transport container for sodium azide solutions in the laboratory. This ... Cheng, Xiongying; Gao, Mingwei (1988). "Biological and genetic effects of combined treatments of sodium azide, gamma rays and ...
1872-1951) and María Mantilla (1880-1962). His mother was said to be the biological daughter of Cuban national hero José Martí ... He reported aboard the Coast Guard-crewed assault transport USS Cavalier in November 1943. According to a press release from ...
When pRNA is in this tetramer ring form, it works as a part of the DNA packaging motor to transport DNA molecules to their ... Journal of Biological Chemistry. 277 (23): 20794-20803. doi:10.1074/jbc.M112061200. ISSN 0021-9258. Grimes, Shelley; Anderson, ...
... is a GnRH antagonist, or an antagonist of the gonadotropin-releasing hormone receptor (GnRHR), the biological target ... and concomitant use with strong organic anion-transporting polypeptide (OATP) 1B1 inhibitors such as ciclosporin and ...
Substances that are transported or inactivated by these proteins, or interfere with them, can interact with velpatasvir. In ... Biological half-life is about 15 hours. Discovery and development of NS5A inhibitors Sofosbuvir/velpatasvir/voxilaprevir, with ...
He transports everyone to Sherwood Forest and casts himself as the Sheriff of Nottingham, Picard as Robin Hood, the crew as the ... with it being all-but-explicitly stated that Q is actually Trelane's biological father, although the truth of this is kept an ...
It is ideal to keep the samplers cold while transporting them in order to preserve the integrity of the samples. After the ... A large number of studies have been performed in which POCIS data was combined with bioassays to measure biological endpoints. ... Testing POCIS extracts in biological assays is useful as a POCIS device samples over its entire deployment period, and ... Second, the contaminant must transport across the membrane either through the water-filled pores or through the membrane itself ...
Unit 731 were covert medical experiment units which conducted biological warfare research and development through human ... Headquarters and transport Three field artillery companies, each with 4 x 75mm field guns (Type 38, Type 90 or Type 95) Cavalry ... or motor transport Divisional signals (250) Medical Unit (900) Up to four Field Hospitals, each of 250 personnel (1000) ... Four engineer companies Materials company Transport regiment (1800) Up to six companies, with either carts, pack horses, ...
... the anterograde and retrograde tracing techniques are based on the visualization of the biological process of axonal transport ... is taken into intracellular organelles and is transported by the endogenous neuronal transport system including kinesin-1, ... Transport of the viral particles along the axon was shown to depend on the microtubular cytoskeleton. There is also a group of ... Norgren RB, McLean JH, Bubel HC, Wander A, Bernstein DI, Lehman MN (March 1992). "Anterograde transport of HSV-1 and HSV-2 in ...
2004). "Phylogeny as a guide to structure and function of membrane transport proteins". Mol Membr Biol. 21 (3): 171-181. doi: ... The Journal of Biological Chemistry. 279 (10): 9532-8. doi:10.1074/jbc.M313100200. PMID 14665618. Chang, Abraham B.; Lin, Ron; ...
The Journal of Biological Chemistry. 271 (8): 4201-4208. doi:10.1074/jbc.271.8.4201. PMID 8626763. Black AC, Luo J, Chun S, ... with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. ...
... biological fuel pellets which are renewable and very clean-burning. Home heating using a pellet stove is an alternative ... Gothic Revival stove in the Nuremberg Transport Museum (Nuremberg, Germany) Renaissance Revival tiled stove in Schloss ...
1952)‎. Transport of biological and pathological materials. World Health Organization. https://apps.who.int/iris/handle/10665/ ...
1952)‎. Transport of biological and pathological materials. World Health Organization. https://extranet.who.int/iris/restricted ...
New targeted therapy using nanotechnology for transport of macro-molecules across biological barriers. ...
Biological Transport * Subject Areas on Research. * 22Na+ and 86Rb+ transport in vascular smooth muscle of SHR, Wistar Kyoto, ... Cerebral glucose transport and metabolism in preterm human infants. * Cerebral transport and metabolism of 1-11C-D-glucose ... Transport properties of the calcium ionophore ETH-129. * Transport rather than diffusion-dependent route for nitric oxide gas ... Cystine and lysine transport in cultured human renal epithelial cells. * Cystine-glutamate transport interactions in rat renal ...
A supramolecular hydrophobic guest transport system based on a biological macrocycle Y. Ge, X. Shen, H. Cao, Y. Hao, L. Jin, J ...
Biological physics of selective protein and gene transport across the nuclear envelope at University of Leeds, listed on ... Cellular logistics: Biological physics of selective protein and gene transport across the nuclear envelope. University of Leeds ... Cellular logistics: Biological physics of selective protein and gene transport across the nuclear envelope. ... Transport is gated by the nuclear pore permselectivity barrier, a meshwork of intrinsically disordered proteins and transport ...
... origins and numbers of mustelids transported to New Zealand for biological control of rabbits. Biological Invasions, 1-13. ... Pandoras box down-under: origins and numbers of mustelids transported to New Zealand for biological control of rabbits. King, ... This paper describes one of the worlds first large-scale experiments in biological control of a major vertebrate pest of ...
... is a key step of your quality process-the integrity of previous sampling phases and/or later analysis ... BIOLOGICAL TRANSPORT. BIOLOGICAL TRANSPORT Guarantee temperatures during transport of your biological samples ... specially designed for laboratories and biological transport companies.. To monitor sample temperatures and be immediately ... Biological transport is a key step of your quality process-the integrity of previous sampling phases and/or later analysis ...
Ionophore constructed from non-covalent assembly of a G-quadruplex and liponucleoside transports K+-ion across biological ... Moreover, the ionophore transports K+-ions across CHO and K-562 cell membranes. This study may serve as a design principle to ... The selective transport of ions across cell membranes, controlled by membrane proteins, is critical for a living organism. DNA- ... The preferential K+-ion transport is presumably due to conformational changes of the ionophore in response to different ions. ...
The Biological Physics and Soft Matter group aims to use bespoke technology and analytical methods borrowed from the Physical ... The Biological Physics and Soft Matter group aims to use bespoke technology and analytical methods borrowed from the Physical ... Understanding the role of mechanics in nucleocytoplasmic transport. Andreu, I., Granero-Moya, I., Garcia-Manyes, S. & Roca- ... The Biological Physics and Soft Matter group aims to use bespoke technology and analytical methods borrowed from the Physical ...
... and the loading and transport of poultry to processing facilities face a number of potential health hazards. ... Biological Hazards. CDC and NIOSH Publications and Research:. *CDC Diseases and Conditions: Avian Influenza Infection [Bird Flu ... Poultry Breeding, Farming, and Transport. Individuals involved in poultry breeding, farming, and the loading and transport of ... Infections and resultant health effects may occur due to exposures to biological agents including viruses (e.g., avian ...
... which is three orders of magnitude higher than the rate of lipid transport catalyzed by biological enzymes. Furthermore, we ... Here the authors design a DNA nanostructure that catalyzes the transport of lipids between bilayers at a rate three orders of ... Through a combination of microscopic simulations and fluorescence microscopy we find the lipid transport rate catalyzed by the ... Consisting of only eight strands, our DNA nanostructure spontaneously inserts into biological membranes by forming a toroidal ...
... resilient transport systems. ... In the event of a biological incident in particular, medical ... Combined Joint Chemical, Biological, Radiological and Nuclear (CBRN) Defence Task Force * Weapons of mass destruction ... NATOs 2022 Chemical, Biological, Radiological and Nuclear (CBRN) Defence Policy establishes the framework upon which we will ... Biological agents, including both existing and modified pathogens, also pose unique and enduring challenges to NATO operations ...
Transport in plants. * 14. Transport in animals. * 15. Coordination and control in plants ... Biological Science covers both core and option material for AS Level and A Level. ...
Fate in this concept consists of a summary of transport (from their input in the environment, transport within the ... Microphysics-chemistry-transport model development and application VALDEBENITO Alvaro M. PAL Sandip BEHRENDT Andreas WULFMEYER ... transport among compartments and long-range transport in the environment) and transformation processes (abiotic and biotic ... It is based on exploration of the causality among chemical (presence of chemical compounds in the environment) and biological ( ...
A simple and inexpensive container for the transport of biological specimens in limited resource situations ... A simple and inexpensive container for the transport of biological specimens in limited resource situations ... International biological reference preparations for epidemic infectious diseases * Tafenoquine versus Primaquine to Prevent ...
Transport bags of biological samplesThe bags for transporting biological samples are provided with the writing and symbol ... Transport bags of biological samples. The bags for transporting biological samples are provided with the writing and symbol " ... biological samples bag 350 x 500 mm - no document pocket. 500pcs. 0668. biological samples bag 400 x 600 mm - no document ... biological samples bag 160 x 170 mm - document pocket color (transparent). 2500pcs. ...
Soft Matter and Biological Physics Enabling a sustainable, functional and resource-efficient next generation of materials by ... Experimental methods in transport and soft matter physics. *Introduction to NMR/MRI for imaging and flow visualization ...
iframe src="https://video.yckmc.edu.hk/embed/4547/" width="480" height="360" frameborder="0" allowfullscreen,,/iframe ...
Physical, chemical, and biological factors that influence the persistence and movement of a contaminant within and across ... Determining Fate and Transport Processes. Fate and transport are interdependent processes. Fate is what eventually happens to ... Ways That Fate and Transport Mechanisms Can Influence Potential Exposure Points. Ways That Fate and Transport Mechanisms Can ... In addition, find out how chemical and site-specific factors may affect contaminant transport in this fate and transport ...
Traffic : the International Journal of Intracellular Transport [electronic resource]. by .. Material type: Computer file; ... International Journal of Intracellular Transport.Online access: Click here to access online Availability: Items available for ...
New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a ... New insight into a central biological dogma on ion transport. New research results from Aarhus University and New York ... transport, while ion pumps mediate slow and active uphill transport against an electrochemical gradient. Both processes are ... "To me the most fascinating part of this whole thing is that it is a break with the boxes we normally like to put our biological ...
Dust catchers: Biological crusts influence the climate May 17, 2022 Chemistry (E&C) Climate Ecology (E&C) ... Humans transport dangerous smoke residues indoors. A team of scientists discovered that people carry hazardous compounds from ... Human transport of thirdhand tobacco smoke: A prominent source of hazardous air pollutants into indoor non-smoking environments ... The paper is significant since studies on THS-related VOCs in non-smoking environments do not exist and while THS transport to ...
Pleural Transport Physiology: Insights from Biological Marker Measurements in Transudates ... Pleural Transport Physiology: Insights from Biological Marker Measurements in Transudates Eleni Apostolidou*, 1, Irini Tsilioni ... The biological markers studied were lactate dehydrogenase (LDH), adenosine deaminase (ADA), interleukin-6 (IL-6), C-reactive ... The aim of this study was to evaluate the physicochemical properties of the pleural mesothelial barrier and of the biological ...
Biological substance (Category B). Service charge for shipments containing biological substances, category B (UN3373). ... Special goods transport. In accordance with international transportation regulations (IATA, ADR, etc…), we can manage special ... Dangerous Goods in Excepted Quantities in accordance with IATA Dangerous Goods Regulations, which can be transported via Air. ... Service charge for the handling and transport of shipments containing Dry Ice (UN 1845). ...
Intelligent Transport Systems: 7 Methods by Which to Optimize Processes. From FLIR Systems 7 Dec 2021 ... chemical and biological sensors. Our goal is to become the world leader in both... ...
Monte Carlo simulations describe the dependence of the Relative Biological Effectiveness of photon radiation with energies ... In a first attempt to explain the energy dependence of the RBE obtained by experiment, the radiation transport for the blood ... When biological tissue is irradiated with ionizing radiation, the biological effectiveness (i.e. the type and number of the ... To compare the biological effects of radiations of different quality, the Relative Biological Effectiveness (RBE) is indicated ...
M17.00009: Flow and transport in the spinal canal. Part 2: On the dispersion rate of a drug delivered intrathecally. Jenna J ... Session M19: Biological Fluid Dynamics: Flying Insects. Chair: Laura Miller, University of North Carolina at Chapel Hill. Room ... M17.00008: Flow and transport in the spinal canal. Part 1: Eulerian velocity field. Antonio Luis Sanchez, Jenna J Lawrence, ... M17.00010: Flow and transport in the spinal canal. Part 3: Effects of canal geometry and dura-membrane compliance. Candido ...
pollutant cycling/loss and transport Watershed Description:. 24.7 km^2 Stroubles Creek, located in the town of Blacksburg in ... An assessment of the reference watershed approach for TMDLs with biological impairments ...
BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance ...
  • The membrane insertion catalyzes spontaneous transport of lipid molecules between the bilayer leaflets, rapidly equilibrating the lipid composition. (nature.com)
  • Through a combination of microscopic simulations and fluorescence microscopy we find the lipid transport rate catalyzed by the DNA nanostructure exceeds 10 7 molecules per second, which is three orders of magnitude higher than the rate of lipid transport catalyzed by biological enzymes. (nature.com)
  • The aim of this study was to evaluate the physicochemical properties of the pleural mesothelial barrier and of the biological markers that facilitate or eliminate the passage of molecules through the pleura. (openrespiratorymedicinejournal.com)
  • Several other factors may influence the transport of the above molecules to pleural cavity, such as their charge and shape. (openrespiratorymedicinejournal.com)
  • Within melanocytes, the P protein may transport molecules into and out of structures called melanosomes (where melanin is produced). (medlineplus.gov)
  • The latest comes from the University of Edinburgh, where Professor Arjun Berera offers another possible method for the transport of life-bearing molecules. (universetoday.com)
  • Membrane proteins whose primary function is to facilitate the transport of molecules across a biological membrane. (bvsalud.org)
  • In particular, we are interested in how molecules are transported into, out of, and. (harvard.edu)
  • Fate in this concept consists of a summary of transport (from their input in the environment, transport within the environmental compartment, where they are discharged, transport among compartments and long-range transport in the environment) and transformation processes (abiotic and biotic transformations). (muni.cz)
  • Possible transport processes that can carry a contaminant away from its source. (cdc.gov)
  • Fate and transport are interdependent processes. (cdc.gov)
  • Tight control of pH is necessary for most biological processes. (medlineplus.gov)
  • Biological Processes Affecting the Distribution of Pollutants in Marine Sediments. (epa.gov)
  • Biological processes were important in maintaining this sink, especially since carbon overconsumption at a C:N ratio of 9.6 was observed in the spring bloom. (soton.ac.uk)
  • Presenting for the first time a practical, design-oriented, interdisciplinary approach to transport phenomena involving biological systems, Biological Process Engineering emphasizes the common aspects of the three main transport processes-fluid flow, heat transfer, and mass transfer. (hyfoma.com)
  • In clear and simple terms, it explores the relevance of these processes to broadly defined biological systems such as the growth of microbes in bioreactors, the leaching of pollutants into groundwater, and the chemistry of food manufacturing. (hyfoma.com)
  • Readers will find: * Systems diagrams comparing and contrasting different transport processes * Biological examples for all types of systems, including metabolic pathways, locomotion, reproduction, responses to thermal conditions, and more * Numerous design charts and procedures * An extensive collection of tables of parameter values, not found in any other text. (hyfoma.com)
  • An ideal undergraduate text for biological engineering students taking courses in transport processes, Biological Process Engineering is also an excellent reference for practicing engineers. (hyfoma.com)
  • This tutorial recognizes the importance of food as a source of energy that will fuel many biological processes. (biologyonline.com)
  • Your partner for all packaging and transportation of infectious, hazardous substances, diagnostic specimens, and biological samples either across town or around the world. (bio-bottle.com)
  • Use this microscope for observing biological specimens, samples from nature, small parts, fabric samples, and many other possibilities. (khanscope.com)
  • NHANES collected biological specimens (biospecimens) for laboratory analysis to provide detailed information about participants' health and nutritional status. (cdc.gov)
  • Suspected and confirmed SARS-CoV-2 positive clinical specimens, cultures, or isolates should be packed and shipped as UN 3373 Biological Substance, Category B. (cdc.gov)
  • 1. NATO's security environment has grown more complex and challenging since 2009, when Allies agreed NATO's Comprehensive, Strategic -Level Policy for Preventing the Proliferation of Weapons of Mass Destruction (WMD) and Defending against Chemical, Biological, Radiological and Nuclear (CBRN) Threats . (nato.int)
  • NATO's 2022 Chemical, Biological, Radiological and Nuclear (CBRN) Defence Policy establishes the framework upon which we will understand, plan, posture, exercise, train, equip, and assess our capabilities, in order to counter WMD proliferation and ensure that we deter and defend our Alliance against CBRN threats. (nato.int)
  • 3. NATO's populations, territories and forces will be defended and secure against the threat or use of chemical, biological, radiological or nuclear materials and weapons of mass destruction. (nato.int)
  • CBRN materials" refers to any chemical, biological, radiological, or nuclear substance that may pose a hazard to NATO populations, territories and forces, regardless of origin or whether the material was originally conceived as a weapon. (nato.int)
  • While this guidance is generally focused on the initial response to potential biological threats, all personnel responding to such incidents must be aware of the potential for exposure to hazardous chemical and/or radiological materials in addition to biological hazards. (cdc.gov)
  • Any such letters/packages must also be evaluated by the HAZMAT unit for only a broad class of radiological and chemical threats prior to being released to law enforcement personnel for transport. (cdc.gov)
  • The LRN was established in 1999, and it's an integrated domestic and international network of laboratories designed to respond quickly to biological, chemical, and radiological threats and other high-priority public health emergencies. (cdc.gov)
  • Any of a group of enzymes which mediate the phenomenon of active transport (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed). (bvsalud.org)
  • The coordinated transport of proteins and nucleic acids between the nucleus and the cytosol is vital for proper gene expression and cell function, and hijacked by viruses to propagate. (findaphd.com)
  • The selective transport of ions across cell membranes, controlled by membrane proteins, is critical for a living organism. (nanion.de)
  • Included in this broad category are proteins involved in active transport (BIOLOGICAL TRANSPORT, ACTIVE), facilitated transport and ION CHANNELS . (bvsalud.org)
  • It introduces the reader to diverse biological phenomena, serves as a stepping-stone to more theoretical topics, and provides important insights into the fast-growing arena of biological engineering. (hyfoma.com)
  • This project will be supervised by Professor Mark Emmerson, Dr Sarah Helyar, and Dr Paul Caplat of Queen's University School of Biological Sciences. (qub.ac.uk)
  • The School of Biological Sciences provides PhD and MPhil (research degree) programmes in subjects ranging from basic biochemistry, molecular genetics and cancer research, to agricultural science, marine ecology and the economic evaluation of ecosystem services and food retailing. (qub.ac.uk)
  • Biological Invasions, 1-13. (waikato.ac.nz)
  • While the study of invasive species can be done within many subfields of biology, the majority of research on invasive organisms has been within the field of ecology and geography where the issue of biological invasions is especially important. (wikipedia.org)
  • Much of the study of invasive species has been influenced by Charles Elton's 1958 book The Ecology of Invasion by Animals and Plants which drew upon the limited amount of research done within disparate fields to create a generalized picture of biological invasions. (wikipedia.org)
  • Biological invasions are widely recognised as one of the main threats to biodiversity, along with habitat destruction. (europa.eu)
  • Grasping at the routes of biological invasions: a framework for integrating pathways into policy. (europa.eu)
  • Infections and resultant health effects may occur due to exposures to biological agents including viruses (e.g., avian influenza virus and West Nile virus), bacteria (e.g. (cdc.gov)
  • In 2007, the Centre for Disease Control (CDC) showed that 385,000 occupational exposures to biological material involving needlestick objects occur annually among health workers 2 . (bvsalud.org)
  • In this PhD project, you will devise new methods to study the physical and molecular mechanisms that make transport selective. (findaphd.com)
  • It is based on exploration of the causality among chemical (presence of chemical compounds in the environment) and biological (mechanisms of effects on the living organisms) part of the problem of chemical contamination of the environment. (muni.cz)
  • We are interested in understanding transport mechanisms in the cell. (harvard.edu)
  • Marine non-indigenous species may arrive and enter a new region mainly through three broad mechanisms: importation of a commodity, arrival in a transport vector and/or natural spread from a neighbouring region where the species is itself alien. (europa.eu)
  • Basic objective of the research plan is complex approach to study of interactions among chemical compounds present in environmental compartments and their biological effects, study of the fate of mainly persistent chemical compounds in the environment, their effects on the environment and living organisms including human. (muni.cz)
  • Physical, chemical, and biological factors that influence the persistence and movement of a contaminant within and across environmental media, which can be important in determining whether opportunities for human exposure exist. (cdc.gov)
  • With more than 25 years of experience, Innovative Sensor Technology IST AG is one of the leading providers of physical, chemical and biological sensors. (azosensors.com)
  • Our Sustainable Water MS concentration gives you skills and experience with issues and approaches in water quality engineering from fundamental physical, chemical and biological perspectives, with applications to both natural and engineered systems. (cmu.edu)
  • According to Ordinance 3.214/78 of the Ministry of Labour and Employment, occupational hazards can be classified as chemical, biological, ergonomic, mechanical and physical 1 . (bvsalud.org)
  • The Biological Physics and Soft Matter group aims to use bespoke technology and analytical methods borrowed from the Physical Sciences to address important fundamental questions in Biology. (kcl.ac.uk)
  • The biological sciences, or the life sciences, encompass a broad spectrum of subjects from molecular biology to ecology as well as such disciplines as biochemistry, biophysics, genetics and physiology. (brocku.ca)
  • The program is designed to provide the student with a broad base in modern biological thought, to fulfill the basic requirements for admission to professional and advanced degree studies and to prepare graduates for careers in the biological sciences and related fields. (brocku.ca)
  • The honours year provides students with the opportunity for either broadening their understanding of the biological sciences or for increased specialization. (brocku.ca)
  • Students must apply to the Department of Biological Sciences in order to be admitted to year 4 (honours). (brocku.ca)
  • Prerequisite requirements are strictly enforced in Biological Sciences courses. (brocku.ca)
  • This section describes factors to consider when evaluating fate and transport of environmental contaminants, the second element of the exposure pathway evaluation. (cdc.gov)
  • Fate and transport" refers to how the nature of contaminants might change (chemically, physically, or biologically) and where they go as they move through the environment. (cdc.gov)
  • Fate and transport evaluations help you determine how likely it is that 1) contaminants have moved or will move beyond the source area, and 2) contamination could migrate and exposures could occur beyond the sampled areas. (cdc.gov)
  • But if you are not able to adequately characterize the fate and transport of contamination, you cannot rule out that contaminants traveled to relevant site-specific media. (cdc.gov)
  • An international team of scientists from the Max Planck Institute for Chemistry and Yale University now discovered that tobacco smoke off-gassing from prior exposure transports contaminants equivalent to several cigarettes of secondhand smoke. (mpg.de)
  • Moreover, the ionophore transports K + -ions across CHO and K-562 cell membranes. (nanion.de)
  • Consisting of only eight strands, our DNA nanostructure spontaneously inserts into biological membranes by forming a toroidal pore that connects the membrane's inner and outer leaflets. (nature.com)
  • New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families. (au.dk)
  • Fat provides the most energy … Practice: Biological macromolecules. (usermessage.de)
  • Biological macromolecules review. (usermessage.de)
  • Benchmarks: SC.912.L.18.1 Describe the basic molecular structures and primary functions of the four major categories of biological macromolecules. (usermessage.de)
  • Traffic : the International Journal of Intracellular Transport [electronic resource]. (who.int)
  • International Journal of Intracellular Transport. (who.int)
  • Intracellular transport by single-headed kinesin KIF1A: effects of single-motor mechanochemistry and steric interactions. (semanticscholar.org)
  • Intracellular transport of single-headed molecular motors KIF1A. (semanticscholar.org)
  • A model of intracellular transport by interacting molecular motors that captures explicitly not only the effects of adenosine triphosphate hydrolysis, but also the ratchet mechanism which drives individual motors is developed. (semanticscholar.org)
  • Based on the measurements, we conclude that humans transport THS into indoor areas via their clothing and bodies. (mpg.de)
  • Individuals involved in poultry breeding, farming, and the loading and transport of poultry to processing facilities face a number of potential health hazards. (cdc.gov)
  • This section provides links to information and investigations about the evaluation and control of these and other potential hazards during poultry breeding, farming, and transport. (cdc.gov)
  • The experimental work will be accompanied by theoretical work to aid the analysis of the experimental data and develop an understanding of the molecular and soft matter physics underpinning selective nucleo-cytoplasmic transport. (findaphd.com)
  • In accordance with international transportation regulations (IATA, ADR, etc…), we can manage special transport & handling services for the classified and designated substances and commodities. (tnt.com)
  • Service charge for shipments containing biological substances, category B (UN3373). (tnt.com)
  • This document replaces the WHO Guidance on regulations for the transport of infectious substances 2011-2012 . (who.int)
  • Infectious substances are transported for a variety of different reasons, within countries and across international borders. (who.int)
  • If you determine that the nature and extent of contamination in all relevant media have been adequately characterized after reviewing pertinent studies, you might need little or no fate and transport evaluation. (cdc.gov)
  • This paper reviews information from the existing literature and the EU GMOS (Global Mercury Observation System) project to assess the current scientific knowledge on global mercury releases into the atmosphere, on global atmospheric transport and deposition, and on the linkage between environmental contamination and potential impacts on human health. (mdpi.com)
  • These measurements helped the rover team design hardware and sampling methods that meet stringent biological contamination control requirements. (nasa.gov)
  • The risk of contamination by biological material is inherent in anything exposed to it, but it varies according to the activities undertaken by workers. (bvsalud.org)
  • Transport of nitrate and ammonium during stream flow events from a southeastern USA Coastal Plain in-stream wetland - 1997 to 1999. (usda.gov)
  • Not every site requires a comprehensive fate and transport analysis to categorize exposure pathways. (cdc.gov)
  • Dangerous Goods in Excepted Quantities in accordance with IATA Dangerous Goods Regulations, which can be transported via Air. (tnt.com)
  • Experiments and interpretation of findings, reported here, clearly support the general nature of the idiotype concept in manipulating biological systems to correct pathological conditions or to improve the immune adaptation to environmental factors. (elsevier.com)
  • However, in environments with very little potassium present, this potential cannot maintain inward flux, and active transport through potassium pump systems rapidly takes over to directly drive the uptake of potassium. (au.dk)
  • For the first time, a joint research collaboration between Aarhus University and New York University have visualized a potassium transporting structure where members from channel and pump super-families come together in a large complex to create active transport. (au.dk)
  • One 'pump-like' subunit creates the energy input (similar to a motor), while a 'channel-like' subunit has been re-purposed to function as an active carrier mediating transport of potassium against a 10,000 fold gradient. (au.dk)
  • These are all the hallmarks of active transport known from other pump systems, but here they only work if all elements of the complex are together. (au.dk)
  • This compilation is especially relevant to present and future investigations of the biological carbon pump (BP), which transports carbon to the deep ocean and regulates atmospheric CO 2 levels. (us-ocb.org)
  • Following the implementation of these regulations, Casadevall and Relman ( 2010 ) proposed that the policies may have the unintended consequence of hindering necessary research on countermeasures and potentially increasing societal vulnerability to biological attacks and natural epidemics. (cdc.gov)
  • Recent events have changed the manner in which scientists acquire and work with pathogenic microorganisms and biological toxins (Morse and Weirich, 2011 ). (cdc.gov)
  • Singlet oxygen causes damage to biological structures within range of diffusion. (medscape.com)
  • 1952)‎. Transport of biological and pathological materials. (who.int)
  • The vials were then refrigerated or frozen before transport to laboratories across the United States. (cdc.gov)
  • Events over the past 15 years have resulted in the promulgation of regulations in the United States to enhance biosecurity by restricting the access to pathogens and toxins (i.e., biological select agents and toxins [BSATs]), which pose a severe threat to human being, animal, or plant health or to animal or plant products, to qualified institutions, laboratories, and scientists. (cdc.gov)
  • The Celestron Labs CB1000CF Compound Binocular microscope offers all the essential features you need in a lab-ready Biological microscope at an economical price. (khanscope.com)
  • This Celestron Labs CB1000CF Compound Binocular microscope is especially great for doing biological examination, because it includes an Abbe type Substage Condenser with Iris Adjustment. (khanscope.com)
  • This CB1000CF Compound Binocular Biological microscope from Celestron has an excellent focusing mechanism with coarse and fine focus control knobs, on separate knobs for precise focus control. (khanscope.com)
  • Idiotypy in Biology and Medicine aims to serve the increasing interest and involvement in the practical aspects of idiotypy in biological systems. (elsevier.com)
  • Although the undergraduate program provides students with flexibility in selecting the areas of biology most compatible with their interests and skills, it also ensures that students develop an overview of the major concepts and problems of modern biology as expressed at all levels of biological organization. (brocku.ca)
  • Occupational exposure to biological material via sharps is high among health workers. (bvsalud.org)
  • To characterise the outcomes of accidents at work involving the exposure of workers to biological agents, in the ABC Paulista region. (bvsalud.org)
  • Plagued by errors and noises hidden in PPI data, these computational methods have undertaken to focus on the prediction of functions by integrating the topology of protein interaction networks and multi-source biological data. (biomedcentral.com)
  • Despite effective improvement of these computational methods, it is still challenging to build a suitable network model for integrating multiplex biological data. (biomedcentral.com)
  • Experimental results indicated that PHN performs significantly better than competing methods and improves the Area Under the Receiver-Operating Curve (AUROC) in Biological Process (BP), Molecular Function (MF) and Cellular Components (CC) by no less than 33%, 15% and 28%, respectively. (biomedcentral.com)
  • A unique, accessible guide to the application of engineering methods to biological systems. (hyfoma.com)
  • Sensitivity to experimental conditions is also explored and it is shown that alternate methods like optical traps provide an even better technique for biological agent detection. (silverchair.com)
  • International Air Transport Association (IATA) training for proper shipping dangerous goods. (cdc.gov)
  • yet, how this meshwork enables rapid yet highly selective transport is not well understood. (findaphd.com)
  • Fluorescence assays, electrophysiology measurements and molecular dynamics simulations reveal that MG/h-TELO preferentially transports K + -ions in a stimuli-responsive manner. (nanion.de)
  • A comparison of an unmanned survey vessel manned vessels for nearshore tidal current and transport measurements. (lsu.edu)
  • In a multidisciplinary environment, you will learn to create bottom up biosynthetic models of the permselectivity barrier and develop advanced optical microscopy techniques to track molecular transport within these nanoscale barriers. (findaphd.com)
  • No correlation between the molecular radius and the pleural fluid to serum ratio of the above biological markers was found. (openrespiratorymedicinejournal.com)
  • In: Proceedings of the American Society of Agricultural and Biological Engineers Annual International Meeting, July 29-August 1, 2012, Dallas, Texas, Paper #12-1337658. (usda.gov)
  • In plasma, verteporfin is transported primarily by low-density lipoproteins (LDL). (medscape.com)
  • Section 3 takes the issue of idiotype-antiidiotype out of the realm of the immune system and discusses it as a new principle to analyze and manipulate biological systems in general. (elsevier.com)
  • We found that acellular BALF is effective in dispersing nanoparticle s without masking the particles biological surface activity. (cdc.gov)
  • Team members wanted to understand the transport of biological particles when the rover is taking rock cores. (nasa.gov)
  • The blood-brain barrier (BBB) transport of choline was compared between stroke-prone spontaneously hypertensive rats (SHRSP) and normotensive Wistar KY rats (WKY). (elsevier.com)
  • Kang, YS, Terasaki, T & Tsuji, A 1990, ' Dysfunction of Choline Transport System through Blood-Brain Barrier in Stroke-Prone Spontaneously Hypertensive Rats ', journal of pharmacobio-dynamics , vol. 13, no. 1, pp. 10-19. (elsevier.com)
  • This is required by the laboratory in an effort to protect the staff members who will ultimately be opening the container and performing definitive biological testing and/or forensic examinations. (cdc.gov)
  • Biological examinations did not reveal any peculiarities. (bvsalud.org)
  • The extracts from the Recommendations on the Transport of Dangerous Goods, Model Regulations , 17th revised edition, New York and Geneva, United Nations, 2011 are reproduced by kind permission of the United Nations. (who.int)
  • The fate and transport analysis is generally a qualitative exercise that does not require quantitative evaluations (modeling studies). (cdc.gov)
  • Depending on your site, you might consider different types of information when evaluating fate and transport. (cdc.gov)
  • The extent to which you examine fate and transport issues depends on many factors, such as the availability of site-specific environmental data sets, the complexity of site issues, and community health concerns. (cdc.gov)
  • You can often obtain pertinent fate and transport information in site investigation reports. (cdc.gov)
  • All Superfund remedial investigation reports, for example, include contaminant- and media-specific fate and transport information. (cdc.gov)
  • When evaluating and interpreting fate and transport information, you might need to consult technical experts (e.g., hydrogeologists, air modelers), especially when more quantitative analyses are needed to characterize affected media. (cdc.gov)
  • When Is a Fate and Transport Evaluation Required? (cdc.gov)
  • Health assessors often use their professional judgment when evaluating environmental fate and transport. (cdc.gov)
  • You do not have to run a hydrology and bioaccumulation model to prove that fate and transport exists, nor do you have to step through every contaminant and physical property of PCBs to evaluate their fate and transport. (cdc.gov)
  • Learn about key types of contaminant fate and transport information collected during the PHA process. (cdc.gov)
  • Learn more details about fate and transport . (cdc.gov)
  • Biological transport is a key step of your quality process-the integrity of previous sampling phases and/or later analysis phases depends on it. (mappingcontrol.com)
  • The disease process involves a complex interaction among fluid dynamics, mass transport and changes in cell type and function in the arterial intima. (duke.edu)
  • The primary function of the skin is to act as a protective barrier against the harsh external environment and protect the delicate chemistries and biological process occurring inside the body. (mactac.com)
  • It presented new technologies covering the whole process of waste management: treatment, transport, collection, disposal, recovery and recycling. (asiatoday.com)
  • Service charge for the handling and transport of shipments containing Dry Ice (UN 1845). (tnt.com)
  • Biosafety is considered an inclusive part of safety and hygiene at work, involving healthcare workers in workplaces where there are not only biological risk factors present, but also other dangers that may directly aggravate health or can be "triggers" for biological accidents 3 . (bvsalud.org)
  • The bags for transporting biological samples are provided with the writing and symbol "Biohazard" in compliance with the Decree Law 493/96 and the UNI EN ISO 7010 standard. (kaltek.it)
  • Participants' demographics, clinical data including PMH, diagnosis information, treatment information and biological samples will be collected locally at study sites at the following timepoints: baseline, one year after diagnosis and annually thereafter for five years (in the first instance with the intention to extend follow-up). (who.int)
  • These samples will be transported to the lead site (Edinburgh) for storage and analysis. (who.int)
  • Accordingly, the decreased choline concentration in the brain interstitial fluid ascribed to the specific dysfunction of the BBB choline transport has been demonstrated in SHRSP. (elsevier.com)
  • This study compare the apical leakage of roots obturated with GuttaCore™, lateral condensation, and continuous wave obturation through a computerized fluid-transport system. (bvsalud.org)
  • After this period, the roots were connected to a computerized fluid-transport system, and the apical leakage was analyzed. (bvsalud.org)
  • This was due to a strong northward Florida Straits dissolved organic nitrogen transport. (soton.ac.uk)
  • 3) The rate of monocyte entry into the vessel wall represents the interaction among cells in luminal flow, the presence of secondary flows which transport the cell to the surface, adhesion molecule expression, and local mass transport of chemotactic agents released by the endothelium and intimal macrophages. (duke.edu)