A ketose sugar that is commonly used in the commercial synthesis of ASCORBIC ACID.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.
The directed transport of ORGANELLES and molecules along nerve cell AXONS. Transport can be anterograde (from the cell body) or retrograde (toward the cell body). (Alberts et al., Molecular Biology of the Cell, 3d ed, pG3)
The movement of ions across energy-transducing cell membranes. Transport can be active, passive or facilitated. Ions may travel by themselves (uniport), or as a group of two or more ions in the same (symport) or opposite (antiport) directions.
Membrane proteins whose primary function is to facilitate the transport of molecules across a biological membrane. Included in this broad category are proteins involved in active transport (BIOLOGICAL TRANSPORT, ACTIVE), facilitated transport and ION CHANNELS.
The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
A large group of membrane transport proteins that shuttle MONOSACCHARIDES across CELL MEMBRANES.
The rate dynamics in chemical or physical systems.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The process by which ELECTRONS are transported from a reduced substrate to molecular OXYGEN. (From Bennington, Saunders Dictionary and Encyclopedia of Laboratory Medicine and Technology, 1984, p270)
Transport proteins that carry specific substances in the blood or across cell membranes.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Vesicles that are involved in shuttling cargo from the interior of the cell to the cell surface, from the cell surface to the interior, across the cell or around the cell to various locations.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Established cell cultures that have the potential to propagate indefinitely.
Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.
Membrane proteins whose primary function is to facilitate the transport of negatively charged molecules (anions) across a biological membrane.
Membrane proteins whose primary function is to facilitate the transport of positively charged molecules (cations) across a biological membrane.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
A stack of flattened vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough ENDOPLASMIC RETICULUM and directing them to secretory vesicles, LYSOSOMES, or the CELL MEMBRANE. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus and fuse with the Golgi, lysosomes or cell membrane. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990)
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A broad category of proteins involved in the formation, transport and dissolution of TRANSPORT VESICLES. They play a role in the intracellular transport of molecules contained within membrane vesicles. Vesicular transport proteins are distinguished from MEMBRANE TRANSPORT PROTEINS, which move molecules across membranes, by the mode in which the molecules are transported.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Cellular proteins and protein complexes that transport amino acids across biological membranes.
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
Elements of limited time intervals, contributing to particular results or situations.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.
A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
Methods of creating machines and devices.
Skin irritant and allergen used in the manufacture of polyurethane foams and other elastomers.
The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.
Organic compounds that contain the -NCO radical.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.
Aquaporin 1 forms a water-specific channel that is constitutively expressed at the PLASMA MEMBRANE of ERYTHROCYTES and KIDNEY TUBULES, PROXIMAL. It provides these cells with a high permeability to WATER. In humans polymorphisms of this protein result in the Colton blood group antigen.
Thin layers of tissue which cover parts of the body, separate adjacent cavities, or connect adjacent structures.
Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)
The structural parts of the VIRION.
Substances that comprise all matter. Each element is made up of atoms that are identical in number of electrons and protons and in nuclear charge, but may differ in mass or number of neutrons.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
The deliberate and methodical practice of finding new applications for existing drugs.
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.

Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. (1/29779)

Drosophila Armadillo and its vertebrate homolog beta-catenin are key effectors of Wingless/Wnt signaling. In the current model, Wingless/Wnt signal stabilizes Armadillo/beta-catenin, which then accumulates in nuclei and binds TCF/LEF family proteins, forming bipartite transcription factors which activate transcription of Wingless/Wnt responsive genes. This model was recently challenged. Overexpression in Xenopus of membrane-tethered beta-catenin or its paralog plakoglobin activates Wnt signaling, suggesting that nuclear localization of Armadillo/beta-catenin is not essential for signaling. Tethered plakoglobin or beta-catenin might signal on their own or might act indirectly by elevating levels of endogenous beta-catenin. We tested these hypotheses in Drosophila by removing endogenous Armadillo. We generated a series of mutant Armadillo proteins with altered intracellular localizations, and expressed these in wild-type and armadillo mutant backgrounds. We found that membrane-tethered Armadillo cannot signal on its own; however it can function in adherens junctions. We also created mutant forms of Armadillo carrying heterologous nuclear localization or nuclear export signals. Although these signals alter the subcellular localization of Arm when overexpressed in Xenopus, in Drosophila they have little effect on localization and only subtle effects on signaling. This supports a model in which Armadillo's nuclear localization is key for signaling, but in which Armadillo intracellular localization is controlled by the availability and affinity of its binding partners.  (+info)

Meiosis: MeiRNA hits the spot. (2/29779)

The protein Mei2 performs at least two functions required in fission yeast for the switch from mitotic to meiotic cell cycles. One of these functions also requires meiRNA. It appears that meiRNA targets Mei2 to the nucleus, where it can promote the first meiotic division.  (+info)

Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. (3/29779)

The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water channels facilitate fluid movement between airspace, interstitial, and capillary compartments, we measured passive and active fluid transport in AQP1 and AQP4 knockout mice. Airspace-capillary osmotic water permeability (Pf) was measured in isolated perfused lungs by a pleural surface fluorescence method. Pf was remarkably reduced in AQP1 (-/-) mice (measured in cm/s x 0.001, SE, n = 5-10: 17 +/- 2 [+/+]; 6.6 +/- 0.6 AQP1 [+/-]; 1.7 +/- 0.3 AQP1 [-/-]; 12 +/- 1 AQP4 [-/-]). Microvascular endothelial water permeability, measured by a related pleural surface fluorescence method in which the airspace was filled with inert perfluorocarbon, was reduced more than 10-fold in AQP1 (-/-) vs. (+/+) mice. Hydrostatically induced lung interstitial and alveolar edema was measured by a gravimetric method and by direct measurement of extravascular lung water. Both approaches indicated a more than twofold reduction in lung water accumulation in AQP1 (-/-) vs. (+/+) mice in response to a 5- to 10-cm H2O increase in pulmonary artery pressure for five minutes. Active, near-isosmolar alveolar fluid absorption (Jv) was measured in in situ perfused lungs using 125I-albumin as an airspace fluid volume marker. Jv (measured in percent fluid uptake at 30 min, n = 5) in (+/+) mice was 6.0 +/- 0.6 (37 degrees C), increased to 16 +/- 1 by beta-agonists, and inhibited to less than 2.0 by amiloride, ouabain, or cooling to 23 degrees C. Jv (with isoproterenol) was not affected by aquaporin deletion (18.9 +/- 2.2 [+/+]; 16.4 +/- 1.5 AQP1 [-/-]; 16.3 +/- 1.7 AQP4 [-/-]). These results indicate that osmotically driven water transport across microvessels in adult lung occurs by a transcellular route through AQP1 water channels and that the microvascular endothelium is a significant barrier for airspace-capillary osmotic water transport. AQP1 facilitates hydrostatically driven lung edema but is not required for active near-isosmolar absorption of alveolar fluid.  (+info)

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation. (4/29779)

In COS cells, Ral GDP dissociation stimulator (RalGDS)-induced Ral activation was stimulated by RasG12V or a Rap1/Ras chimera in which the N-terminal region of Rap1 was ligated to the C-terminal region of Ras but not by Rap1G12V or a Ras/Rap1 chimera in which the N-terminal region of Ras was ligated to the C-terminal region of Rap1, although RalGDS interacted with these small GTP-binding proteins. When RasG12V, Ral and the Rap1/Ras chimera were individually expressed in NIH3T3 cells, they localized to the plasma membrane. Rap1Q63E and the Ras/Rap1 chimera were detected in the perinuclear region. When RalGDS was expressed alone, it was abundant in the cytoplasm. When coexpressed with RasG12V or the Rap1/Ras chimera, RalGDS was detected at the plasma membrane, whereas when coexpressed with Rap1Q63E or the Ras/Rap1 chimera, RalGDS was observed in the perinuclear region. RalGDS which was targeted to the plasma membrane by the addition of Ras farnesylation site (RalGDS-CAAX) activated Ral in the absence of RasG12V. Although RalGDS did not stimulate the dissociation of GDP from Ral in the absence of the GTP-bound form of Ras in a reconstitution assay using the liposomes, RalGDS-CAAX could stimulate it without Ras. RasG12V activated Raf-1 when they were coexpressed in Sf9 cells, whereas RasG12V did not affect the RalGDS activity. These results indicate that Ras recruits RalGDS to the plasma membrane and that the translocated RalGDS induces the activation of Ral, but that Rap1 does not activate Ral due to distinct subcellular localization.  (+info)

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA. (5/29779)

The nature of the broad substrate specificity phenomenon, as manifested by multidrug resistance proteins, is not yet understood. In the Escherichia coli multidrug transporter, MdfA, the hydrophobicity profile and PhoA fusion analysis have so far identified only one membrane-embedded charged amino acid residue (E26). In order to determine whether this negatively charged residue may play a role in multidrug recognition, we evaluated the expression and function of MdfA constructs mutated at this position. Replacing E26 with the positively charged residue lysine abolished the multidrug resistance activity against positively charged drugs, but retained chloramphenicol efflux and resistance. In contrast, when the negative charge was preserved in a mutant with aspartate instead of E26, chloramphenicol recognition and transport were drastically inhibited; however, the mutant exhibited almost wild-type multidrug resistance activity against lipophilic cations. These results suggest that although the negative charge at position 26 is not essential for active transport, it dictates the multidrug resistance character of MdfA. We show that such a negative charge is also found in other drug resistance transporters, and its possible significance regarding multidrug resistance is discussed.  (+info)

Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation. (6/29779)

The proton motive force (PMF) renders protein translocation across the Escherichia coli membrane highly efficient, although the underlying mechanism has not been clarified. The membrane insertion and deinsertion of SecA coupled to ATP binding and hydrolysis, respectively, are thought to drive the translocation. We report here that PMF significantly decreases the level of membrane-inserted SecA. The prlA4 mutation of SecY, which causes efficient protein translocation in the absence of PMF, was found to reduce the membrane-inserted SecA irrespective of the presence or absence of PMF. The PMF-dependent decrease in the membrane-inserted SecA caused an increase in the amount of SecA released into the extra-membrane milieu, indicating that PMF deinserts SecA from the membrane. The PMF-dependent deinsertion reduced the amount of SecA required for maximal translocation activity. Neither ATP hydrolysis nor exchange with external SecA was required for the PMF-dependent deinsertion of SecA. These results indicate that the SecA deinsertion is a limiting step of protein translocation and is accelerated by PMF, efficient protein translocation thereby being caused in the presence of PMF.  (+info)

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. (7/29779)

Stimulation of the hepatocyte growth factor (HGF) receptor tyrosine kinase, Met, induces mitogenesis, motility, invasion, and branching tubulogenesis of epithelial and endothelial cell lines in culture. We have previously shown that Gab1 is the major phosphorylated protein following stimulation of the Met receptor in epithelial cells that undergo a morphogenic program in response to HGF. Gab1 is a member of the family of IRS-1-like multisubstrate docking proteins and, like IRS-1, contains an amino-terminal pleckstrin homology domain, in addition to multiple tyrosine residues that are potential binding sites for proteins that contain SH2 or PTB domains. Following stimulation of epithelial cells with HGF, Gab1 associates with phosphatidylinositol 3-kinase and the tyrosine phosphatase SHP2. Met receptor mutants that are impaired in their association with Gab1 fail to induce branching tubulogenesis. Overexpression of Gab1 rescues the Met-dependent tubulogenic response in these cell lines. The ability of Gab1 to promote tubulogenesis is dependent on its pleckstrin homology domain. Whereas the wild-type Gab1 protein is localized to areas of cell-cell contact, a Gab1 protein lacking the pleckstrin homology domain is localized predominantly in the cytoplasm. Localization of Gab1 to areas of cell-cell contact is inhibited by LY294002, demonstrating that phosphatidylinositol 3-kinase activity is required. These data show that Gab1 is an important mediator of branching tubulogenesis downstream from the Met receptor and identify phosphatidylinositol 3-kinase and the Gab1 pleckstrin homology domain as crucial for subcellular localization of Gab1 and biological responses.  (+info)

Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression. (8/29779)

Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. Here we show that signaling triggered by VEGF induced DNA-binding and transcriptional activities of nuclear factor of activated T cells (NFAT) and AP-1 in human umbilical vein endothelial cells (HUVECs). VEGF also induced TF mRNA expression and gene promoter activation by a cyclosporin A (CsA)-sensitive mechanism. As in lymphoid cells, NFAT was dephosphorylated and translocated to the nucleus upon activation of HUVECs, and these processes were blocked by CsA. NFAT was involved in the VEGF-mediated TF promoter activation as evidenced by cotransfection experiments with a dominant negative version of NFAT and site-directed mutagenesis of a newly identified NFAT site within the TF promoter that overlaps with a previously identified kappaB-like site. Strikingly, this site bound exclusively NFAT not only from nuclear extracts of HUVECs activated by VEGF, a stimulus that failed to induce NF-kappaB-binding activity, but also from extracts of cells activated with phorbol esters and calcium ionophore, a combination of stimuli that triggered the simultaneous activation of NFAT and NF-kappaB. These results implicate NFAT in the regulation of endothelial genes by physiological means and shed light on the mechanisms that switch on the gene expression program induced by VEGF and those regulating TF gene expression.  (+info)

Your biology students will learn about the cell membrane and ins-and-outs of cell transport in this engaging, effective, and fun interactive web lesson. The Cell Transport Webquest includes 6 pages of EDITABLE student questions that include fill in the blank and graphic organizer
Get an in-depth review and ask questions about Cell Transport Physiology (part 1/5). See what people are saying about Cell Transport Physiology (part 1/5).
This resource includes everything you need to teach cell transport with little to no prep- and offers many editable resources, as well! The unit includes a suggested unit planner to help guide you through it. These resources are fresh and fun- so if youre looking to diffuse your cell transport materials into a new direction, this is for you! This unit can be used as a stand alone curriculum or as
The transport of S-cysteine conjugates was studied in the kidney cell line, LLC-PK1, using the nephrotoxin, S-(1,2-dichlorovinyl)-L-cysteine (L-DCVC), as the model compound. The saturable uptake of this conjugate did not require sodium and was selectively inhibited by the amino acid transport system L-specific substrate, 2-amino-2-norbornane carboxylic acid, as well as a variety of other S-cysteine conjugates and neutral amino acids with large, nonpolar side chains. Kinetic studies suggested the existence of both low and high affinity transport systems with Km values that differed by 25-fold. Although these uptake systems showed no discernible differences in substrate specificity, the low affinity transport was more sensitive to trans-stimulation. L-DCVC uptake in subconfluent cultures was about 3-fold that of confluent cells, suggesting either adaptive regulation to cell growth or polarization of transport to the basolateral membrane. L-DCVC toxicity in LLC-PK1 cells was inhibited in the ...
Newly synthesized proteins and lipids are transported across the Golgi complex via different mechanisms whose respective roles are not completely clear. We previously identified a non-vesicular intra-Golgi transport pathway for glucosylceramide (GlcCer)--the common precursor of the different series of glycosphingolipids-that is operated by the cytosolic GlcCer-transfer protein FAPP2 (also known as PLEKHA8) (ref. 1). However, the molecular determinants of the FAPP2-mediated transfer of GlcCer from the cis-Golgi to the trans-Golgi network, as well as the physiological relevance of maintaining two parallel transport pathways of GlcCer--vesicular and non-vesicular--through the Golgi, remain poorly defined. Here, using mouse and cell models, we clarify the molecular mechanisms underlying the intra-Golgi vectorial transfer of GlcCer by FAPP2 and show that GlcCer is channelled by vesicular and non-vesicular transport to two topologically distinct glycosylation tracks in the Golgi cisternae and the trans-Golgi
Cell transport is the movement of items into and out of the cell through the cells membrane. This movement is done with a variety of proteins to facilitate the action....
Knowing the structure and properties of the transporter molecule may be the key to changing the way that some chemotherapies, for example, could work in the body to prevent tumor growth, said senior author Seok-Yong Lee, PhD, assistant professor of biochemistry at Duke.. The article was published in Nature online on March 11.. The transporter molecule, called a concentrative nucleoside transporter, works by moving nucleosides, the building blocks of DNA and RNA, from the outside to the inside of cells. It also transports nucleoside-like chemo drugs through cell membranes.. Once inside the cells, the nucleoside-like drugs are modified into nucleotides that are incorporated into DNA in ways that prevent tumor cells from dividing and functioning.. We discovered the structure of the transporter molecule, and now we believe it is possible to improve nucleoside drugs to be better recognized by a particular form of the transporter molecule that resides in certain types of tissue, Lee said. Now we ...
Kucharczyk, R, Kierzek, AM, Slonimski, PP and Rytka, J (2001) The Ccz1p interacts with Ypt7 GTPase in the process of fusion of multiple transport intermediates with the vacuole in S.cerevisiae. ...
RAVINDRA KUMAR, ERRAMPALLI MADHU and ANIL MAAN, Central Road Research Institute, India; SANJEEV SINHA, National Institute of Technology Patna, India Purpose: The purpose of this paper is to determination of Combined Exposure Factor (CEF) of different transport related environmental pollutants by a...
Rapid and extensive biliary excretion of [d-penicillamine2,5]enkephalin (DPDPE) in rats as the unchanged peptide suggests that multiple transport proteins may be involved in the hepatobiliary disposition of this zwitterionic peptide. Although DPDPE is a P-glycoprotein substrate, the role of other transport proteins in the hepatic clearance of DPDPE has not been established. Furthermore, the ability of various experimental approaches to quantitate the contribution of a specific hepatic uptake or excretion process when multiple transport systems are involved has not been addressed. 3H-DPDPE uptake in suspended Wistar rat hepatocytes was primarily (,95%) due to temperature-dependent transport mechanisms; similar results were obtained in suspended hepatocytes from Mrp2-deficient (TR-) rats. Pharmacokinetic modeling revealed that saturable and linear processes were involved in 3H-DPDPE uptake in hepatocytes. The use of transport modulators suggested that hepatic uptake of 3H-DPDPE was mediated by ...
TY - JOUR. T1 - Potassium transport in normal and transformed mouse 3T3 cells. AU - Spaggiare, S.. AU - Wallach, M. J.. AU - Tupper, J. T.. PY - 1976. Y1 - 1976. N2 - The components of unidirectional K influx and efflux were investigated in the 3T3 cell and the SV40 transformed 3T3 cell in exponential and stationary growth phase. Over the cell densities used for transport experiments the 3T3 cell goes from exponential growth to density dependent inhibition of growth (4 x 104 to 4 x 105 cell cm-2) whereas the SV40 3T3 maintains exponential or near exponential growth (4 x 104 to 1 x 106 cell cm-2). In agreement with previous observations, volume per cell and mg protein per cell decrease with increasing cell density. Thus, transport measurements were expressed on a per volume basis. Total unidirectional K influx and effluxin the 3T3 cell is approximately double that of the SV40 3T3 cell at all cell densities investigated. Both cell types have similar volumes initially and show similar decreases ...
Author: Hasselbach, Wilhelm et al.; Genre: Book Chapter; Published in Print: 1974; Title: Anion specific carriers in the sarcoplasmic membranes
Buy TRANSPORT MODELS OF PRESTON items on eBay. Find a huge selection of items and get what you want today TRANSPORT MODELS OF PRESTON items - Get great deals on items on eBay Stores!
Buy TRANSPORT MODELS OF PRESTON items on eBay. Find a huge selection of items and get what you want today TRANSPORT MODELS OF PRESTON items - Get great deals on items on eBay Stores!
View Notes - Lecture 26 from KIN 110 at UMass (Amherst). Kin 110Lecture #26 Monday April 12th, 2010 Components of Blood Red blood cells: transport oxygen o Deliver oxygen from lungs to other tissues
Over the last few years scientists have been successful in identifyin...Now Howard Hughes Medical Institute investigator A HREFhttp://ww...If you look at the history of breakthroughs in disease often the u...In the brains of patients with Alzheimers disease a peptide called...Using mouse neurons as a model the scientists showed that APP serv...,Defective,cell,transport,suggested,in,Alzheimers,disease,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
This website uses cookies to help you receive a better online experience. By using this website, you are agreeing to the use of cookies as explained in our privacy policy ...
Cells may be specialised for a particular function.. The structure will allow them to carry this function out.. Leaf cell - Absorbs light energy for photosynthesis, packed with chloroplasts. Regular shaped, closely packed cells from a continuous layer for efficient absorption of sunlight.. Root hair cell - Absorbs water and mineral ions from the soil, long finger-like process with very thin wall, which gives a large surface area. Sperm cell - Fertilises an egg cell - female gamete, the head contains genetic information and an enzyme to help pentrate the egg cell membrane. The middle section is packed with mitochondria for energy. The tail moves the sperm to the egg.. Red blood cells - Contains haemoglobin to carry oxygen to the cells, thin outer membrane to let oxygen diffuse through easily. Shape increases the surface area to allow more oxygen to be absorbed efficiently. No nucleus, so the whole cell is full of haemoglobin.. ...
Some molecules like water fit easily through the openings in the cell membrane. They simply flow in and out, always moving from the side where there are more to the side where there are less of them, or down the concentration gradient from high concentration to low ...
TERM 2002: Paving the way for EU enlargement - Indicators of transport and environment integration. The report examines progress made in the transport sector in implementing the principle, adopted by EU leaders at their Cardiff summit in 1998, of integrating environmental concerns into other policy areas.. Based on a set of key indicators of progress - or lack of it - the report finds that transport trends in both the EU and accession countries are moving away from, not closer to, the main environmental objectives of EU policies on transport and sustainable development.. These call for breaking the close link between economic growth and transport expansion, as well as stabilising the modal split - the market shares of the different transport modes - at 1998 levels by 2010, then shifting traffic from the roads back to rail and inland waterways.. The report shows, for instance, that in the EU and accession countries energy consumption by transport and the associated emissions of greenhouse gases ...
This lab simulates the action potential of a neuron using the membrane channel simulator. Students are directed through the process of setting up their membrane like the membrane of a neuron and performing the steps of an action potential ...
This lab simulates the action potential of a neuron using the membrane channel simulator. Students are directed through the process of setting up their membrane like the membrane of a neuron and performing the steps of an action potential ...
My strengths is that I pay attention in class and take down important notes. From taking down extra notes, I can more information and it also make me understand better. My weakness is that I am not able to spell in familiar words and I will write long answers so I will not have time to complete the paper. I also find it difficult to self-study since I will not know how to study before the test so I just remembered stuff which I was quite weak in and the mistakes I made for the past pop-quiz. And the reason for doing average for my science, I was anxious of not completing the paper so I only got part of the marks. So in the future, before the exam, I think I should read through all the notes and summarize all the topics like what are cancer cells. And in the sentence, I must make sure that I have all the keywords.. ReplyDelete ...
bestbooklibrary matches keywords, searched from 3rd-party sites, to affiliate-networks offering unlimited access to licensed entertainment content. bestbooklibrary allows visitors, otherwise looking for free-content to enjoy more for less. ...
Active and Passive Transport. Chapter 5. 1. Passive Transport . Movement of materials in and out of the cell Requires no energy to happen. Two Types of Passive Transport. Diffusion: When substance moves that is dissolved in water Osmosis: When water moves across the membrane. Slideshow 6854745 by humphrey-askew
Whats the difference between Active Transport and Passive Transport? Active and passive transport are biological processes that move oxygen, water and nutrients into cells and remove waste products. Active transport requires chemical energy because it is the movement of biochemicals from areas of lower concentration to are...
Cellular Transport The lipid bilayer acts as a barrier to what kind of molecule from PCB 2099 at Florida International University
Short, helpful video on the topic of cellular transport by top AP US Biology teacher, Patrick. Videos are produced by leading online education provider, Brightstorm.
HYDROGEOCHEM 2 - reactive multispecies-multicomponent chemical transport model - hydrologic transport and mixed geochemical kinetic/equilbrium reactions in saturated/unsaturated media
Role of Lipids in the Regulation of Transport Processes across biological membranes. We aim for a holistic molecular description how specific lipids regulate transport of ions, nutrients and compatible solutes across cell membranes and between chemically distinct organelles. Diverse chemo-physical stimuli are involved the regulation of membrane channels and carriers; some of them linked to the adaptation to environment stress. Although these sensing and regulation mechanisms are very divers in all three kingdoms of life the common theme is an essential role of the lipids in stimuli perception and signal transduction. By solving atomic structures of individual transporters and channels in their native membrane environment and in complex with regulatory proteins in combination with functional measurements and spectroscopy we want to determine a molecular movie of lipid-mediated transport regulation.. ...
WP3. Cell biophysics and physiology (IBF): WP3 will be lead by IBF. This work package is focus in the biophysical and physiological characterization of the anionophores and the assessment of the physiological impact of the anionophore-induced anion transport on normal and cystic fibrosis bronchial cell models. Up to date very little is known about the fundamentals of transmembrane anion transport. WP3 will asses several aspects of anionophore activity which are crucial for further development of these compounds as drugs. Electrophysiological characterization of compounds will be obtained using voltage clamp in frog oocytes and patch clamp in mammalian cells. It includes a detailed functional analysis (transport efficiency, ionic composition dependence, pH dependence, temperature effects, voltage dependence), pharmacological analysis, and cell distribution of compounds by biochemical methods. Of particular relevance is the effect in the bronchial epithelial cell, which is among the most affected ...
The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cells ability to make the proteins necessary for essential biological functions. Until now, it ...
A system and computer program product for tracking and monitoring assets along a transport route. The system includes at least one receiver for receiving asset identifications transmitted from the as
Learn about shipping dangerous goods globally. Stay current on transport regulations affecting hazard classification, packaging, marking labeling and documentation.
The alkylating peptide PSF shows very promising results in vitro on different cancer cells but its efficacy in animals has not been assessed. Here we evaluate the efficacy of PSF in human melanoma-bearing nude mice and examine the underlying mechanis
Modes of Membrane Transport Transmembrane Transport movement of small substances through a cellular membrane (plasma, ER, mitochondrial..) ions, fatty acids, H 2 O, monosaccharides, steroids, amino acids
Pittsburgh, PA. Reduced models of flow or mass transport in heterogeneous media are often adopted in the computational approach when the geometrical configuration of the system at hand is too complex. A paradigmatic example in this respect is blood flow through a network of capillaries surrounded by a porous interstitium. We numerically address this biological system by a computational model based on a multiscale resolution of embedded domains. Exploiting their large aspect ratio, we avoid resolving the complex 3D geometry of the submerged vessels by representing them with a 1D geometrical description of their centerline and the resulting network [1,2].. Cancer employs mass transport as a fundamental mechanism of coordination and communication and the physics of mass transport within body compartments and across biological barriers differentiates cancer from healthy tissues [3]. Mass transport is also at the basis of cancer pharmacological treatment Delivery of diagnostic and therapeutic agents ...
Direct carrier transport measurements were performed for different InGaAsP/InGaAlAs MQW test structures. Shallow InGaAlAs barrier QW showed faster carrier transport. Semi-insulating regrown FP lasers with InGaAlAs barrier QW showed improved high temperature operation, modal gain, differential modal gain and chirp.. ...
Active Transport vs Passive Transport As minute as they are, cells in the body carry some very important processes deep within. These processes are all vital to
Crash Course Biology: In Da Club - Membranes and Transport, by Hank Essential Biology 2.4: Membranes For lots more animations on cell structure and function and cell transport, visit North Harris College. You can also work through the Membranes lessons from HippoCampus Biology. ..........o0O0o.......... Membrane Structure: The Fluid Mosaic Model Fluid Mosaic Model Tutorial from…
Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. Several important examples of their role in drug disposition and drug-drug interactions have been described to date. Investigation of drug-drug interactions at the transport protein level are therefore of increasing interest to the academic, industrial and regulatory research communities.. The gene expression of transport proteins involved in drug transport was investigated in the jejunum, liver, kidney and colon to better understand their influence on the ADMET properties of drugs. In addition, the gene and protein expression of transport proteins in cell lines, widely used for predictions of drug transport and metabolism, was examined.. The substrate and inhibitor heterogeneity ...
Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. Several important examples of their role in drug disposition and drug-drug interactions have been described to date. Investigation of drug-drug interactions at the transport protein level are therefore of increasing interest to the academic, industrial and regulatory research communities.. The gene expression of transport proteins involved in drug transport was investigated in the jejunum, liver, kidney and colon to better understand their influence on the ADMET properties of drugs. In addition, the gene and protein expression of transport proteins in cell lines, widely used for predictions of drug transport and metabolism, was examined.. The substrate and inhibitor heterogeneity ...
Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. Several important examples of their role in drug disposition and drug-drug interactions have been described to date. Investigation of drug-drug interactions at the transport protein level are therefore of increasing interest to the academic, industrial and regulatory research communities.. The gene expression of transport proteins involved in drug transport was investigated in the jejunum, liver, kidney and colon to better understand their influence on the ADMET properties of drugs. In addition, the gene and protein expression of transport proteins in cell lines, widely used for predictions of drug transport and metabolism, was examined.. The substrate and inhibitor heterogeneity ...
In experiments on transport tissues in plants, researchers from Heidelberg University were able to identify factors of crucial importance for the formation of the plant tissue known as phloem. According to Prof. Dr Thomas ...
Research into the mechanism of how cells transport nutrients, conducted at the Max Planck Institute of Colloids and Interfaces in Potsdam, has produced a m
Almost one third of all kilometres travelled on roads in Germany today consist of commercial transport; a third of it is freight transport. 4 million companies rely on an efficient transport system every day. More than 80 million people receive services and parcels at home...
Introduction. Road Canals Railways Word Count: 2,575 Contents Page Page 1 - Title Page Page 2 - Contents Page Page 3 - Introduction Page 4-5 - Road Page 6-7 - Canal Page 8-9 - Railway Page 10 - Conclusion Page 11 - Evaluation Page 12 - Bibliography Introduction This term the class 9M have been studying the subject of transport between 1750 and 1900. Now we have to do a project on transport during that period, in particular looking at roads, canals and railways. In this project I will be finding out four main things: * What transport was like before 1750 ? * Why did it need improving ? * How did each type of transport improve ? * How did this help the Industrial Revolution ? Hopefully this project will help you learn more about transport in the past and I hope you enjoy it. Below is a timeline diagram of the transportation between 1750 and 1900 just as a guide ! Road(1700) The need for better roads The increase in population, improvements in farming and growth of industry at the time increased ...
In TOS, presume there was a safety system in the transporter. What it did was this... if the matter stream was lost during transport but the pattern template made it through, the system could supply matter from an emergency stock within the transporter and use the pattern to recreate the lost matter stream. So, when Kirk beamed up the mystery rock stuff scrambled the transporter controls and we can assume it did two things - firstly, it duplicated and distorted the template pattern so that there were two versions of it in the system, each a distorted version of Kirk. For some reason the transporter operator didnt realise this had happened; so he picked one of the patterns, the good Kirk, and he rematerialised it using Kirks original matter stream. As far as hes concerned something went wrong, but they got Kirk through okay. The console, thinking it now had a second person in transport, would presumably flash some sort of alert, but I think we have to assume that the transporter guy missed ...
1. The present study has determined the kinetics of the uptake of L-3,4-dihydroxyphenylalanine (L-DOPA) and 3-O-methyl-L-DOPA (3-OMDOPA) in rat renal tubules and examined the effect of 3-OMDOPA on the inward transport of L-DOPA and on its conversion into dopamine in kidney homogenates. 2. The accumulation of both L-DOPA and 3-OMDOPA in renal tubules was found to occur through non-saturable and saturable mechanisms. The kinetics of the saturable component of L-DOPA and 3-OMDOPA uptake in renal tubules were as follows: L-DOPA, Vmax = 11.1 nmol mg-1 protein h-1 and Km = 216 microM (n = 6); 3-OMDOPA, Vmax = 8.1 nmol mg-1 protein h-1 and Km = 231 microM (n = 5). The diffusion constant of the non-saturable component for the accumulation of L-DOPA and 3-OMDOPA was 0.0010 and 0.0014 mumol-1, respectively. 3. 3-OMDOPA (100 to 2000 microM) was found to produce a concentration-dependent decrease (29% to 81% reduction) of the saturable component of the tubular uptake of L-DOPA; the Ki value of 3-OMDOPA for
The transport properties for phenylalanine and glucose in luminal-membrane vesicles from outer cortex (pars convoluta) and outer medulla (pars recta) of rabbit kidney were studied by a spectrophotometric method. Uptake of phenylalanine as well as of glucose by the two types of membrane vesicles was found to be Na+-dependent, electrogenic and stereospecific. Na+-dependent transport of L-phenylalanine by outer-cortical membrane vesicles could be accounted for by one transport system (KA congruent to 1.5 mM). By contrast, in the outer-medullary preparation, L-phenylalanine transport occurred via two transport systems, namely a high-affinity system with K1A congruent to 0.33 mM and a low-affinity system with K2A congruent to 7 mM respectively. Na+-dependent uptake of D-glucose by pars convoluta and pars recta membrane vesicles could be described by single, but different, transport systems, namely a low-affinity system with KA congruent to 3.5 mM and a high-affinity system with KA congruent to 0.30 ...
This cell transport lab will give your students a hands-on and up-close view of osmosis, diffusion, and plasmolysis in living cells. This lab has two different activities. In the first part of this lab, the observation of plasmolysis in a living cell is a qualitative measurement.
metabolism definition process biology britannica cell transport flow chart worksheet acetyl coenzyme compound release molecule an the only solution across membrane
TY - JOUR. T1 - A new locus in the phosphate specific transport (PST) region of Escherichia coli. AU - Levitz, Ruth. AU - Klar, Avihou. AU - Sar, Nehemia. AU - Yagil, Ezra. PY - 1984/10/1. Y1 - 1984/10/1. N2 - PhoS64 is a mutation in the Phosphate Specific Transport (PST) region on the E. coli chromosome which lacks the periplasmic phosphate binding protein. In contrast to other phoS mutations (which have the same phenotype) it complements the mutations in phoT and pstB. A detailed genetic map of the PST region constructed by three point transductional crosses has revealed that phoS64 is located distally from other phoS mutations. The genetic order obtained was phoS64-phoU35-pstB401-phoT-phoS-ilvC. The data indicate that phoS64 belongs to a different complementation unit in the PST region not known hitherto. We propose to name it phoV.. AB - PhoS64 is a mutation in the Phosphate Specific Transport (PST) region on the E. coli chromosome which lacks the periplasmic phosphate binding protein. In ...
The camera lens diaphragm is an important component in a noncontact optical imaging system and has a crucial influence on the images registered on the CCD camera. However, this influence has not been taken into account in the existing free-space photon transport models. To model the photon transport process more accurately, a generalized free-space photon transport model is proposed. It combines Lambertian source theory with analysis of the influence of the camera lens diaphragm to simulate photon transport process in free space. In addition, the radiance theorem is also adopted to establish the energy relationship between the virtual detector and the CCD camera. The accuracy and feasibility of the proposed model is validated with a Monte-Carlo-based free-space photon transport model and physical phantom experiment. A comparison study with our previous hybrid radiosity-radiance theorem based model demonstrates the improvement performance and potential of the proposed model for simulating photon ...
It has been determined that cortisol and a few other steroids are transported outward from certain mammalian cells growing in vitro. The extrusion process is temperature dependent, glucose dependent, saturable, and operates for only a few selected steroids. Many, but not all, steroids are able to block the extrusion process but are not themselves transported. The outward transport process for steroids has been found in mouse fibroblasts, mouse lymphoma cells, and functional mouse adrenal gland tumor cells growing in vitro. The transport process is not present in two varieties of cells cultured from human sources-HeLa or diploid fibroblasts, WI-38.. ...
Intercellular transport of auxin is driven by PIN-formed (PIN) proteins. PINs are localized at the plasma membrane (PM) and on constitutively recycling endomembrane vesicles. Therefore, PINs can mediate auxin transport either by direct translocation across the PM or by pumping it into secretory vesicles (SVs), leading to its secretory release upon fusion with the PM. Which of these two mechanisms dominates is a matter of debate. Here we addressed the issue with a mathematical modeling approach. We demonstrate that the efficiency of secretory transport depends on SV size, half-life of PINs on the PM, pH, exocytosis frequency and PIN density. 3D-SIM microscopy was used to determine PIN density on the PM. Combing this data with published values of the other parameters, we show that the transport activity of PINs in SVs would have to be at least 1000x greater than on the PM in order to produce a comparable macroscopic auxin transport. If both transport mechanisms operated simultaneously and PINs were
Multi-particle non-equilibrium dynamics in two-channel biological transport systems is investigated theoretically within the framework of asymmetric simple exclusion processes (ASEP). In exclusion processes particles move along the lattice by hopping between neighboring sites that are vacant. We consider the systems with open boundaries, where particles enter the lattice on the entrance site and leave from the exit site with given rates. Four different ASEP models are studied. The first two models investigate interchannel coupling between parallel channels in a one-way transport system. The third model considers junction of two parallel tracks, while the last model investigates two-way transport system with narrow entrances with coupling on the boundaries. Theoretical investigation of these non-equilibrium systems reveal many interesting phenomena, such as unusual phase diagrams that contain up to seven stationary-state phases, localization of the domain wall in the bulk of the system, ...
Transportation can be very stressful for animals due to rough handling, extreme weather and long transport times. Get involved in changing transport laws!
Endothelial cells separate the bloodstream from the underlying tissue and play a crucial role in vascular homeostasis. They also form an important barrier for vascular drug delivery. This thesis contains preliminary studies targeted at understanding the mechanisms of binding and transport across endothelial cells cultured in vitro. Specifically, the first study investigates how the recombinant source of Factor IX (FIX), a blood coagulant protein used in the treatment of Hemophilia B, impacts surface ligand binding (FIX to its specific receptors) to bovine aortic endothelial cells (BAECs). Competitive binding experiments between 125I-FIX and FIX were undertaken to quantify the interaction of recombinant and transgenic FIX with BAECs and human collagen IV and determine if there was a measurable difference in binding affinity. Results indicate limited specific binding of 125I-FIX to BAECs and no binding to human collagen IV. Concrete conclusions were not drawn from this data due to technical issues ...
Inborn Amino Acid Transport Disorders: Disorders characterized by defective transport of amino acids across cell membranes. These include deficits in transport across brush-border epithelial cell membranes of the small intestine (MICROVILLI) and KIDNEY TUBULES; transport across the basolateral membrane; and transport across the membranes of intracellular organelles. (From Nippon Rinsho 1992 Jul;50(7):1587-92)
The SapNP technology allows scientists to work in a detergent free environment however; detergents were initially used to extract the proteins from the membrane. Ideally we would like to eliminate the use of detergents entirely, explains Löw. These developments are ongoing and will allow us to study membrane proteins that cannot be extracted with detergents in the future. Furthermore, the SapNP method is beneficial for studying the structure of membrane proteins by single particle electron cryo-microscopy which avoids the tedious step of growing crystals. The combination of both methods at the CSSBs cryo-EM facility will provide new structural and functional information about membrane proteins such as the human PepT1 and PepT2 transporters, which transport drugs into human cells ...
Biological transport is a key step of your quality process-the integrity of previous sampling phases and/or later analysis phases depends on it. (...)
In order to verify the research from this laboratory that sheep omasal epithelium contains mRNA encoding for a peptide transporter (s) and to determine di- to octapeptide transport capability, poly(A)+ RNA isolated from sheep omasal epithelium was injected into Xenopus laevis oocytes. Poly(A)+ RNA was functionally expressed in Xenopus oocytes 4 to 7 d post-injection. Peptide (5 di-, 10 tri-, 6 tetra-, 2 penta-, 1 hepta-, 1 septa-, 1 octapeptide) transport capability was measured by impaling oocytes with a microelectrode to monitor membrane potential (Vm). Oocytes were maintained in pH 5.5 buffer. Peptide transport was identified as being expressed when, in the presence of a buffered peptide substrate (1 mM), the oocyte membrane showed persistent depolarization (a more positive Vm). In the absence of peptide transport, the membrane became depolarized with the addition of buffered substrate, but rapidly repolarized to the resting potential. Peptide transport was expressed for some di-, tri-, and ...
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth.
The hypothesis tested was that ketoconazole can modulate P-glycoprotein, thereby altering cellular uptake and apparent permeability (P(app)) of multidrug-resistant substrates, such as cyclosporin A (CSA) and digoxin, across Caco-2, MDCKII-MDR1, and MDCKII wild-type cell transport models. (3)H-CSA/(3)H-digoxin transport experiments were performed with and without co-exposure to ketoconazole, and (3)H-ketoconzole transport ...
Specific membrane transporters mediate the passage of a wide variety of substances across cellular membranes. Classes of substrates include amino acids, sugars, cations, anions, vitamins, and water. The number of inherited disorders of membrane transport continues to increase with the identification of new transporters on the plasma membrane or intracellular organelles and the clarification of the molecular basis of diseases with previously unknown pathophysiology. The first transport disorders identified affected the gut or the kidney, but transport processes are now proving essential for the normal function of every organ. Mutations in transporter molecules cause disorders of the heart, muscle, brain, and endocrine and sensory organs (Table 435e-1). Inherited defects impairing the transport of selected amino acids that can present in adults are discussed here as examples of the abnormalities encountered; others are considered elsewhere in this text. ...
We present a numerical study of collisional transport in a tokamak pedestal in the presence of non-trace impurities, using the radially global delta-f neoclassical solver PERFECT [M. Landreman et al. 2014 Plasma Phys. Control. Fusion 56 045005]. It is known that in a tokamak core with non-trace impurities present the radial impurity flux opposes the bulk ion flux to provide an ambipolar particle transport, with the electron transport being negligibly small. However, in a sharp density pedestal with sub-sonic ion flows the electron transport can be comparable to the ion and impurity flows. Furthermore, the neoclassical particle transport is not intrinsically ambipolar, and the non-ambipolarity of the fluxes extends outside the pedestal region by the radial coupling of the perturbations. The neoclassical momentum transport, which is finite in the presence of ion orbit-width scale profile variations, is significantly enhanced when impurities are present in non-trace quantities, even if the total parallel
Copyright Get Revising 2017 all rights reserved. Get Revising is one of the trading names of The Student Room Group Ltd. Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered office: International House, Queens Road, Brighton, BN1 3XE ...
membrane, glucose transmembrane transporter activity, substrate-specific transmembrane transporter activity, sugar:proton symporter activity, glucose import, hexose transmembrane transport, transmembrane transport
Cancer is an extraordinarily complex disease. It is now recognized that methods commonly used in physics can help reducing the complexity of cancer to a manageable set of underlying principles and phenomena [1, 2]. Physical properties of biological barriers control cell, particle, and molecule transport across tissues and this transport and its deregulation play an overarching role in cancer physics. According to [1], tissue invasion is mass transport deregulation at the interface between the cell and the microenvironment; metastasis is a deregulation of local and distant cellular transport at the scale of the organism; tumor-associated angiogenesis completely alters mass and fluid exchange across the microcirculation; alterations in the signaling pathways that accompany the evasion of apoptosis, growth signal dependence and growth inhibitory messages from the immediate environment are also disruptions in molecular transport since molecular signaling depends directly on the transport of ...
Just to extend the answer from @Amory slightly, I think that the terms active and passive transport are best kept for describing transmembrane movement of molecules. In the case of exocytosis the only transmembrane event is when a secreted protein is first inserted (usually cotranslationally) across the endoplasmic reticulum membrane. Im not aware of any evidence that this uses more energy than that already expended during polpeptide elongation by the ribosome. At that point the secreted protein is topologically extracytoplasmic, and everything else is achieved by rounds of vesicle formation and fusion of vesicles with target membranes. The same is true in reverse for endocytosis. Any molecule that is internalised in an endocytic vesicle is still extracytoplasmic unless some process specifically moves it across the membrane of the vesicle, or a downstream organelle such as the endosome. At that point whether the transport process was active or passive would depend upon the properties of the ...
Nitric oxide (NO) is a key endothelial cell (EC) signaling molecule that exerts its actions both within the EC and within heterologous target cells. Most investigators have assumed that NO traverses the plasma membrane of the EC by simple diffusion owing to its relative lipophilicity; however, the possibility of transmembrane channel-dependent transport has not been explored in any detail. In this study, we used bovine aortic ECs to test whether the water channel, aquaporin 1 (AQP1), and glucose transporters, could promote NO efflux from and influx into the EC. We measured NO efflux by activating EC NO synthase with 3 uM A23187, and assaying L-NAME-inhibited NO released into the media by nitrite/nitrate determination. We measured NO influx by incubating ECs with DPTA NONOate after loading the cells with the NO-sensitive intracellular fluorophore, DAF-FM. Using Western blot analysis, AQP1 mRNA was detected by quantitative RT-PCR (in human ECs), but protein expression was only detected with ...
In this study, particle transport and captured behaviors in a Diesel Particulate Filter (DPF) was investigated with Lattice Boltzmann Method. LBM calculation was performed to a 3D-reconstructed micro porous DPF substrate, which was obtained by micro-focus 3D X-ray technique. Simulating advection-diffusion behaviors of diesel particulates in micro porous channel, we adapted a LBM method used for high Peclet number flow, simulating flow conditions in DPFs. We investigated flow behaviors in a wide variety of inlet velocity. LBM simulation has clearly shown that non-dimensional flow field is similar in wide range of flow conditions in the DPF, because flow Reynolds number in the micro porous substrate is sufficiently low, dominated by laminar flow regime. It was also revealed that less than 40% pore channels was responsible for more than 80% volume flux in the porous substrate without particle loading. We also examined particle deposition behaviors in the porous substrate with LBM simulation. It was ...
Stochastic and continuum dynamics in cellular transport. SIAM Minisymposium on Mathematical modeling and simulation of complex biological systems. Joint Mathematics Meetings. January 2020
Protein aggregation can be a critical problem leading to human pathologies such as Alzheimers or Parkinsons disease.. Mitochondria, the compartments that produce most of the cellular energy, contain surface receptors, which facilitate protein uptake. These receptors specifically recognize mitochondrial proteins and direct them through pores into the interior of mitochondria, explains Prof. Johannes Herrmann, a specialist for mitochondrial biology. But, so far, we had no idea what these proteins encounter before they reach the mitochondrial surface. It was just assumed that newly synthesized proteins are directly targeted to their destination compartment.. In a close collaboration with Professor Maya Schuldiner from the Weizmann Institute in Rehovot, Israel, Herrmanns team observed that mitochondrial proteins are initially targeted to the surface of the endoplasmic reticulum (ER). The ER is a cellular compartment that serves as a central sorting station to deliver proteins to various ...
Thank you for sharing this Drug Metabolism & Disposition article.. NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.. ...
One of the most common investigation techniques of type-II superconductors is the transport measurement, in which an electrical current is applied to a sample and the corresponding resistance is measured as a function of temperature and magnetic field. At temperatures well below the critical temperature, Tc, the resistance of a superconductor is usually immeasurably low. But at elevated temperatures and fields, in the so-called vortex liquid phase, a substantial linear resistance is observed1. In this dissipative state, which in anisotropic high-temperature superconductors like Bi2Sr2CaCu2O8 may occupy most of the mixed-state phase diagram, the transport current is usually assumed to flow uniformly across the sample as in a normal metal. To test this assumption, we have devised a measurement approach which allows determination of the flow pattern of the transport current across the sample. The surprising result is that, in Bi2Sr2CaCu2O8 crystals, most of the current flows at the edges of the sample
Such requirements resulted, first, in the evolutionary appearance of more constrained channels that could assume carrier functions, secondly, in the appearance of larger, more complex obligatory secondary carriers that could no longer catalyse passive diffusion and, thirdly, in the emergence of primary active transporters and group translocators with superimposed energy-coupling subunits. Thus, the ancestral precursors of all these transporter types were simple peptide channels. The pathways most frequently taken were evidently tandem intragenic duplications giving rise to larger helical bundles that had the potential to form discrete stereospecific intramembranous substrate binding sites. They could also be constrained for coupling to other transport processes and, through conformational coupling, they were subject to control by a superimposed primary energy-yielding process such as ATP hydrolysis. We assume that none of these requirements could be satisfied by the ancestral one, two or three ...
Such requirements resulted, first, in the evolutionary appearance of more constrained channels that could assume carrier functions, secondly, in the appearance of larger, more complex obligatory secondary carriers that could no longer catalyse passive diffusion and, thirdly, in the emergence of primary active transporters and group translocators with superimposed energy-coupling subunits. Thus, the ancestral precursors of all these transporter types were simple peptide channels. The pathways most frequently taken were evidently tandem intragenic duplications giving rise to larger helical bundles that had the potential to form discrete stereospecific intramembranous substrate binding sites. They could also be constrained for coupling to other transport processes and, through conformational coupling, they were subject to control by a superimposed primary energy-yielding process such as ATP hydrolysis. We assume that none of these requirements could be satisfied by the ancestral one, two or three ...
Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
Four sets of nonreactive solute transport experiments were conducted with micromodels. Each set consisted of three experiments with one variable, i.e., flow velocity, grain diameter, pore-aspect ratio
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (Glut or SLC2A family / solute carrier…
Gentaur molecular products has all kinds of products like :search , Cleaver \ Beta-Storage_Transport Block \ CSR-STORE for more molecular products just contact us
Description: The transport regulations have changed with an aim to facilitate the transport of certain biological materials. What is new? Are these new regulations really clearer and easier to use? What are the problems? Are there country differences and why? Come and share your experiences and questions and lets see if we can agree on common solutions to unclear situations.. Discussion Group 2: European biosafety: a common approach? ...
Neutral molecules transported by a Porin channelsb Ionophoresc Simple diffusion Absence of charge over molecules (Uncharged/Neutral molecules) favours their transport by simple diffusion. Small neutral molecules are usually transported freely across plasma membranes by simple dif
TY - JOUR. T1 - A new approach to the study of ion transport processes by an in situ radiotracer method based on measuring intensity changes and energy spectrum alterations of β-radiation. AU - Németh, Z.. AU - Erdei, L.. AU - Kolics, A.. PY - 1995/3. Y1 - 1995/3. N2 - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the penetration of labeled species. The applicability of the radiotracer technique is detailed through the measurement of the transport of labeled chloride ions into a PERMAPLEX-A20 anion exchanger membrane. The proposed method is applicable to in situ monitoring of the motion of ions in the membrane (or adsorbent).. AB - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the ...
NEW March 2013. 60 pages fitted two to an A4 view. London Transport Regulations concerning the supply and switching of traction current. At the back is a diagrammatic map indicating the sections for the supply. May 1982.. This file will be available to download as soon as payment has been made. You go to your account and click on Downloads. New customers create an account as they place their order.. ? ...
Convection motions within the Sun transport heat from its interior to its surface. The hot regions are seen as granular (∼1000 kilometers across) and supergranular (∼30,000 kilometers across) cells in the Sun. Using data from the Helioseismic Magnetic Imager on the Solar Dynamics Observatory, Hathaway et al. (p. 1217) found evidence for even larger cells that have long been predicted by theory but not unambiguously detected. The flows associated with these giant cells transport angular momentum toward the equator and are important for maintaining the Suns equatorial rotation.. Video follows: GO WITH THE FLOW Long-lasting plasma flows appear in red and blue in this animation, which portrays data from four solar rotations. Some flows persist for several months; these patterns are especially visible near the suns north pole. Scientists think these flows keep the suns equator rotating faster than its poles.. ...
Ground-based remote sensing observations from Aerosol Robotic Network (AERONET) sun-sky radiometers have recently shown several instances where cloud-aerosol interaction had resulted in modification of aerosol properties and/or in difficulty identifying some major pollution transport events due to aerosols being imbedded in cloud systems. Major Distributed Regional Aerosol Gridded Observation Networks (DRAGON) field campaigns involving multiple AERONET sites in Japan and South Korea during Spring of 2012 have yielded observations of aerosol transport associated with clouds and/or aerosol properties modification as a result of fog interaction. Analysis of data from the Korean and Japan DRAGON campaigns shows that major fine-mode aerosol transport events are sometimes associated with extensive cloud cover and that cloud-screening of observations often filter out significant pollution aerosol transport events. The Spectral De-convolution Algorithm (SDA) algorithm was utilized to isolate and analyze ...
Mohammad, H#., Marchisella, F#., Ortega-Martinez, S.#,Hollos, P., Eerola, K., Komulainen, E., Kulesskaya, N.Freemantle, E., Fagerholm, V., Savbontaus, E., Rauvala, H., Peterson, B.D., van Praag, H., Coffey, E. JNK1 controls adult hippocampal neurogenesis and imposes cell autonomous control of anxiety behaviour from the neurogenic niche. Molecular Psychiatry. 2016, In press. #equal contribution. Marchisella, F., Coffey, E.T. *, Hollos, P. Microtubule and microtubule associated protein anomalies in psychiatric disorders. Cytoskeleton. Special review issue on Emerging Concepts in Neuronal Cytoskeleton. 2016 in press. Padzik, A#, Deshpande, P#, Hollos, P#, Franker, M, Rannikko, E, Cai, D, Prus, P, Mågard, M, Westerlund, N, Verhey, K, James, P, Hoogenraad, C, Coffey, ET. KIF5C S176 phosphorylation regulates microtubule binding and transport efficiency in neurons. Frontiers in Cellular Neuroscience. 2016 in press. #equal contribution. Varidaki, A, Mohammad, H, Coffey, ET. Molecular Mechanisms of ...
The amino acid L-carnitine is a cofactor required for the metabolism of fats and their subsequent transport into the mitochondria, where they undergo oxidation and produce energy.* Individuals prone to being deficient in L-carnitine, and for those whom supplementation would be advisable, include individuals on dialysis
It has now become possible for the first time to look into the bodys absolutely fundamental engine compartment, and observe the ion pumps that activate cell transport and signal systems. This function ensures that you and me, and all other biological creatures on Earth, work the way they should with the right biomolecular mechanisms.. The calcium pump may not look like a lot. Each pump only measures a few nanometres, millionths of millimetres, in each direction, and sits in the cell membranes of our bodies. But despite its diminutive size, it is crucial to life. This pump is the reason that our muscles can contract, and that neurons can send signals. If the tiny pump stopped working, cells would stop communicating. Without it, we could neither move nor think. This is why cells use so much of their energy - about a fourth of the bodys fuel known as ATP - to keep the pumps running. ...
Developments in the biological sciences are having a major impact on the world around us. Provides introduction to basic principles of biology. Topics will include: the science of biology, chemical building blocks of life, classification of living things, cell structure and function, cell transport and metabolism, cell division, how genes work and are controlled, genetic
Influence of crystalline Defects on Transport Properties of GaN Grown by Ammonia-Molecular Beam Epitaxy and Magnetron Sputter Epitaxy
A feverish quest exists to uncover the events that lead to cochlear amplification in mammals. The role of the OHC is certainly paramount, and we now have identified many componentsthat form the basis of the cells unique contribution. In my mind, a few observations leadthe story on this hot topic, including the molecular identification of the OHC motor, its modulation by anions and the demonstration of the motors anion transport capabilities. Here I review some of this recent work.. ...
The database details a comprehensive IUBMB approved classification system for membrane transport proteins known as the Transporter Classification (TC) system. The TC system is analogous to the Enzyme Commission (EC) system for classification of enzymes, except that it incorporates both functional and phylogenetic information. Descriptions, TC numbers, and examples of 1534 families of transport proteins are provided. Transport systems are classified on the basis of five criteria, and each of these criteria corresponds to one of the five numbers or letters within the TC# for a particular type of transporter ...
... is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological ... Various attempts have been made by engineers to mimic the process of facilitated transport in synthetic (i.e., non-biological) ... ISBN 0-471-41759-9. Friedman, Morton (2008). Principles and models of biological transport. Springer. ISBN 978-0387-79239-2. ... Being passive, facilitated transport does not directly require chemical energy from ATP hydrolysis in the transport step itself ...
On the air transport of the RF; Air techniques and the objects of civil aviation; Space craft; For nuclear sets, the points of ... storing radioactive materials; Means of protecting the information that include the state secret; Immune biological ... On the federal Railway transport; Means of protection of information; Security of manufacturing of explosives; In the sphere of ... The system of certification of mechanic transport means and trailers; The system of certification of gases; The "SEPROCHIM" ...
"D-Glucose transport in Trypanosoma brucei. D-Glucose transport is the rate-limiting step of its metabolism". European Journal ... The Journal of Biological Chemistry. 269 (1): 21-24. ISSN 0021-9258. PMID 8276796. Gu, F.; Gruenberg, J. (1999-06-04). " ... Robinson, L. J.; Aniento, F.; Gruenberg, J. (1997). "NSF is required for transport from early to late endosomes". Journal of ... Emery, G.; Rojo, M.; Gruenberg, J. (2000). "Coupled transport of p24 family members". Journal of Cell Science. 113 ( Pt 13): ...
"Southeast Asia's First Biological Corridor across the BKE". Land Transport Authority. 15 August 2003. Retrieved 23 October 2013 ... In 2011 the National Parks Board and the Land Transport Authority announced a plan to construct an ecological corridor, the Eco ...
Höfling, Felix; Franosch, Thomas (2013-03-12). "Anomalous transport in the crowded world of biological cells". Reports on ... These dynamics can reveal information about the type of transport being observed (e.g., thermal or active), the medium where ...
Arsenic toxicity Arsenite-transporting ATPase Solute carrier family Active transport ATP-binding cassette transporter Hasgekar ... Biological Trace Element Research. 111 (1-3): 167-183. doi:10.1385/BTER:111:1:167. ISSN 0163-4984. PMID 16943604. S2CID ... which can participate in both secondary transport or primary active transport. Based on operon analyses, Arc3 homologues may ... In the latter case ATP hydrolysis again energizes transport. ...
Biological Membranes: Theory of Transport, Potentials and Electric Impulses. Cambridge University Press (September 26, 2002). ... Electrical signals within biological organisms are, in general, driven by ions. The most important cations for the action ... However, some of the molecules embedded in the membrane are capable either of actively transporting ions from one side of the ... Ion pumps, also known as ion transporters or carrier proteins, actively transport specific types of ions from one side of the ...
Drake, J.A., Mooney, H.A., Castri, F.di., Groves, R.H., Kruger, F.J., Rejmánek, M. and Williamson, M. (1989). Biological ... doi:10.1016/0006-3207(96)00020-1. Cariton, J. T.; Geller, J. B. (1993). "Ecological Roulette: the Global Transport of ... ISBN 0-471-92085-1 Carlton, J (1996). "Pattern, process, and prediction in marine invasion ecology". Biological Conservation. ...
"Engineered Regulated RNA Localization and Transport in Biological Systems". Cite journal requires ,journal= (help) "Niles ... Jacquin Niles is an American Professor of Biological Engineering and Director of the Massachusetts Institute of Technology ...
The transport of inorganic nitrogen in the form of ammonium and the transport of organic nitrogen as amino acids most likely ... "Orchid Mycorrhiza", from Fungal Biology (online textbook), School of Biological Sciences, University of Sydney, June 2004: " ... and transported into the plant cell via ammonium transporters and incorporated into the plant. To accommodate the transport of ... This active transport of carbon from fungi to plant is an exclusively biotorphic reaction but it is thought that a significant ...
Black, Craig Patrick; Snyder, Gregory K (1980). "Oxygen transport in the avian egg at high altitude". American Zoologist. 20 (2 ... Biological Conservation. 79 (2-3): 117-122. doi:10.1016/S0006-3207(96)00118-8. hdl:10261/58104. Laiolo, Paola; Rolando, Antonio ...
"The role of optimal vortex formation in biological fluid transport". Proceedings of the Royal Society B: Biological Sciences. ...
The former can transport aromatic β-glucosides and cellobiose, as well as Chb. However, only Chb induces expression of the chb ... The Journal of Biological Chemistry. 275 (42): 33102-33109. doi:10.1074/jbc.M001045200. ISSN 0021-9258. PMID 10913119. Tilly, K ... IIBSgc, believed to function in pentose transport, is homologous to IIBLac and IIBChb. In Bacillus cereus, the crystal ... Keyhani, N. O.; Bacia, K.; Roseman, S. (2000-10-20). "The transport/phosphorylation of N,N'-diacetylchitobiose in Escherichia ...
Maret, Wolfgang; Wedd, Anthony (2014). Binding, transport and storage of metal ions in biological cells. [S.l.]: Royal Soc Of ...
Due to biological uptake, the photic zone has relatively low levels of nutrient concentrations. As a result, phytoplankton ... The Ekman transport additionally brings more nutrients to the photic zone. Nutrient pulse frequency affects the phytoplankton ... Biological factors include grazing and migrations. Upwelling carries nutrients from the deep waters into the photic zone, ... It undergoes a series of physical, chemical, and biological processes that supply nutrients into the upper water column. The ...
Chart 13, ISBN 978-0-7243-7603-2 Robinson, A. C.; Armstrong, D. M. (eds.). A Biological Survey of Kangaroo Island, South ... Transport and Infrastructure. Archived from the original on 12 October 2016. Retrieved 2 May 2016. Robinson, A. C.; Armstrong, ... Retrieved 27 March 2013.CS1 maint: location (link) Robinson, A. C.; Armstrong, D. M. (eds.). A Biological Survey of Kangaroo ... D. M. (eds.). A Biological Survey of Kangaroo Island, South Australia, 1989 & 1990 (PDF). Adelaide, SA: Heritage and ...
Potter, V. R.; Dubois, K. P. (1943). "Studies on the Mechanism of Hydrogen Transport in Animal Tissues : VI. Inhibitor Studies ... Journal of Biological Chemistry (178): 241-250. PMID 18112108. Retrieved 5 June 2015. ... in the respiratory electron transport chain. It binds to the active site of the enzyme without reacting, competing with the ...
Part of the river's basin is in the Maicuru Biological Reserve. The seventh track of the album Aguas da Amazonia is named after ... List of rivers of Pará Brazilian Ministry of Transport Ziesler, R.; Ardizzone, G.D. (1979). "Amazon River System". The Inland ...
"Transport function and regulation of mitochondrial uncoupling proteins 2 and 3". The Journal of Biological Chemistry. 274 (37 ... Journal of Biological Chemistry, 272(10), pp.6093-6096. According to Google Scholar, this article has been cited 1744 times. In ... FA transport protein), which was found to play a key role in the uptake of dietary fat into the body. Tartaglia´s further ... "Identification of the major intestinal fatty acid transport protein". Molecular Cell. 4 (3): 299-308. doi:10.1016/s1097-2765(00 ...
... rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene ... "The transport of electrons from an electron donor to an electron acceptor." (electron transfer) "The specific processes that ... nuclear transport factor 2 (NTF2), Ran, exportin "Enables the directed movement of charged atoms or small charged molecules ... The list is based on the biological categories described in the GO Slims list for "GOA and whole proteome analysis". ...
It is contrasted with the apoplastic flow, which uses cell wall transport. The symplastic transport was first realized by ... Freeman, Scott (2014). Biological Science. Boston: Benjamin Cummings. ISBN 9780321743671. Tangl, E. (1879). Ueber offene ... Plant, Cell & Environment 26: 1-15, [1]. Apoplast Plant sap Polar auxin transport, a type of cell-to-cell transport Protoplast ... Larger molecules, including transcription factors and plant viruses, can also be transported through with the help of actin ...
It blocks intracellular protein transport, and exhibits antibiotic, antimalarial, and other biological activities. The ... Monensin A is able to transport these cations across lipid membranes of cells in an electroneutral (i.e. non-depolarizing) ... I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells ... Recent studies have shown that monensin may transport sodium ion through the membrane in both electrogenic and electroneutral ...
The biological function of TMEM128 is still poorly understood. As this is a transmembrane protein, common functions may include ... RABAC1, also known as Prenylated Rab acceptor 1, which assists in vesicle transport. TMPRSS2, also known as Transmembrane ...
"Modeling effects of patchiness and biological variability on transport rates within bioturbated sediments". Journal of Marine ... the total sediment transport from redd construction can equal or exceed the sediment transport from flood events. The net ... Bunzl, K (2002). "Transport of fallout radiocesium in the soil by bioturbation: a random walk model and application to a forest ... This greater biological and chemical diversity is thought to have led to the evolution and diversification of seafloor-dwelling ...
Transport of energy and mass is fundamental to many biological and environmental processes. Areas, from food processing ( ... require knowledge of how energy and mass can be transported through materials (momentum, heat transfer, etc.). Cell therapy ...
William McKinnon, Inspector, Sea Transport Survey Office, Glasgow, Ministry of Transport and Civil Aviation. May McLean, Clerk ... Ebenezer Ford, lately Director and Secretary, Scottish Marine Biological Association. Eunice Ellen Frost, Executive Editor, ... Arthur Witcomb Smith, Transport Manager, West Bromwich Corporation. Charles Arthur Murray Kyrke-Smith, Chief Air Traffic ... Teo Loh Swee, Head of the Transport Section, Office of the Commissioner-General for Her Majesty's Government in the United ...
Raven, J.A. (1977). "The evolution of vascular land plants in relation to supracellular transport processes". Advances in ... Barthlott, W.; Neinhuis, C (1997). "Purity of the sacred lotus, or escape from contamination in biological surfaces". Planta. ... Freeman, S. (2002). Biological Science. New Jersey: Prentice-Hall, Inc. ISBN 978-0130819239.. ...
In order to transport cargo into the nucleus, importin-β must associate with the nuclear pore complexes. It does this by ... The Journal of Biological Chemistry. 275 (30): 23139-45. doi:10.1074/jbc.M909256199. PMID 10930427. Winnepenninckx V, Lazar V, ... Members of the importin-β family can bind and transport cargo by themselves, or can form heterodimers with importin-α. As part ... Importin is a type of karyopherin that transports protein molecules from the cell's cytoplasm to the nucleus. It does so by ...
"Water transport mechanism through open capillaries analyzed by direct surface modifications on biological surfaces". Scientific ...
... can be used to manipulate, transport, separate and sort different types of particles. Since biological cells ... As biological cells have dielectric properties dielectrophoresis has many medical applications. Instruments capable of ... Dielectrophoresis can be used to manipulate, transport, separate and sort different types of particles. DEP is being applied in ... DEP has made it possible to characterize and manipulate biological particles like blood cells, stem cells, neurons, pancreatic ...
Walter Pagel (1967). William Harvey's Biological Ideas: Selected Aspects and Historical Background. Karger Publishers. p. 340. ... Comparatively, the astral influences on the macrocosmal Spirit could be transported to the microcosmal Spirit in the blood by ...
Transport portal. *Vice Admiral Emory S. Land, USN. Instrumental in overseeing founding of Academy ...
Mahomoodally, M. F.; Gurib-Fakim, A.; Subratty., A. H.. «Experimental evidence for in vitro fluid transport in the presence of ... Gurib-Fakim, A.; Subratty, H.; Narod, F.; Govinden-Soulange, J.; Mahomoodally, F.. «Biological activity from indigenous ... Cucurbitaceae) induced inhibition of D-glucose, L-tyrosine and fluid transport across rat everted intestinal sacs in vitro». ... fluid and electrolyte transport across rat everted intestine, comparable to insulin action in vitro.». British journal of ...
These proteins mainly transport chemicals and information across the membrane.[3]. The membrane contains many proteins. The ... biological membrane that separates the interior of a cell from its outside environment ...
A Vital Legacy: Biological and Environmental Research in the Atomic Age, U.S. Department of Energy, The Office of Biological ... which has a half-life of 110 minutes and can be transported a reasonable distance before use, or to rubidium-82 (used as ... Psychiatry: Numerous compounds that bind selectively to neuroreceptors of interest in biological psychiatry have been ...
... while major veins are responsible for its transport outside of the leaf. At the same time water is being transported in the ... "Proceedings of the Royal Society B: Biological Sciences. 276 (1654): 121-127. doi:10.1098/rspb.2008.0858. PMC 2614250. PMID ... Vascular plants transport sucrose in a special tissue called the phloem. The phloem and xylem are parallel to each other, but ... Once sugar has been synthesized, it needs to be transported to areas of active growth such as the plant shoots and roots. ...
"West Africa - Ebola virus disease Update: Travel and transport". International travel and health. World Health Organization ( ... May 2002). "Hemorrhagic fever viruses as biological weapons: medical and public health management". Journal of the American ... Transport, travel, contact. Transportation crews are instructed to follow a certain isolation procedure, should anyone exhibit ... It has the potential to be weaponised for use in biological warfare,[226][227] and was investigated by Biopreparat for such use ...
Biological process. • gamma-aminobutyric acid signaling pathway. • chloride transmembrane transport. • ion transport. • ... chloride transport. • ion transmembrane transport. • signal transduction. • chemical synaptic transmission. • regulation of ...
Series B, Biological Sciences. 365 (1541): 729-48. doi:10.1098/rstb.2009.0103. PMC 2817223. PMID 20124341.. ... 4.2 Phosphorylation, chaperones, and transport. *4.3 The translocon on the outer chloroplast membrane (TOC) *4.3.1 Toc34 and 33 ... Phosphorylation, chaperones, and transportEdit. After a chloroplast polypeptide is synthesized on a ribosome in the cytosol, ... The Journal of Biological Chemistry. 271 (11): 6545-54. doi:10.1074/jbc.271.11.6545. PMID 8626459.. ...
Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry. 4: 217-241. doi: ... molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport ...
The degree of disarticluation of fossils suggests the distance they have been transported, and since many species have narrow ... The Biological Bulletin. 211 (3): 248-262. doi:10.2307/4134547. JSTOR 4134547. PMID 17179384.. ...
Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry. 4: 217-241. doi: ... molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport ...
The ancient Romans also had a complex system of aqueducts,[52] which were used to transport water across long distances.[52] ... including the possibility of the permanent alteration of our biological nature. These concerns are shared by other philosophers ... The rise in technology has led to skyscrapers and broad urban areas whose inhabitants rely on motors to transport them and ... Main article: History of transport. Meanwhile, humans were learning to harness other forms of energy. The earliest known use of ...
Biological process. • lipid transport. • positive regulation of sequestering of triglyceride. • triglyceride homeostasis. • ... 2006). "Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in ...
The Biological Bulletin. 197 (1): 26-39. doi:10.2307/1542994. Archived from the original (PDF) on 5 March 2011.. ... Octopus blood contains the copper-rich protein haemocyanin to transport oxygen. This makes the blood very viscous and it ... Octopuses offer many possibilities in biological research, including their ability to regenerate limbs, change the colour of ... haemocyanin transports oxygen more efficiently than haemoglobin. The haemocyanin is dissolved in the plasma instead of being ...
Biological process. • regulation of apoptotic process. • pronephros development. • regulation of metanephric nephron tubule ... cell polarity and transport, cell motility and adhesion.[8] ...
... biological) material. Specifically, diagenesis "is the cumulative physical, chemical and biological environment; these ... or biological change undergone by a sediment after its initial deposition, after its lithification. This process excludes ...
"Proceedings of the Royal Society B: Biological Sciences. 278 (1708): 1090-1097. doi:10.1098/rspb.2010.1579. PMC 3049027. PMID ... Megafauna play a significant role in the lateral transport of mineral nutrients in an ecosystem, tending to translocate them ... "Secretariat of the Convention on Biological Diversity. Retrieved 9 January 2017.. *^ Glowka, Lyle; Burhenne-Guilmin, Françoise ... We have driven the rate of biological extinction, the permanent loss of species, up several hundred times beyond its historical ...
Transport. Transport describes how illumination in a scene gets from one place to another. Visibility is a major component of ... Rendering may simulate light transport to create realistic images or it may create images that have a particular artistic style ... The two basic operations in realistic rendering are transport (how much light passes from one place to another) and scattering ... light transport. Scattering. Models of scattering and shading are used to describe the appearance of a surface. In graphics ...
The Journal of Biological Chemistry. 279 (26): 27008-16. doi:10.1074/jbc.M403588200. PMID 15090535.. ... It is a naturally occurring polar auxin transport inhibitor.[5] ... Influence of Auxin Polar Transport". The Plant Cell. 9 (10): ... quercetin undergoes rapid and extensive metabolism that makes the biological effects presumed from in vitro studies unlikely to ... "The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems". (review). Food & ...
Rafinesque was one of the first to use the term "evolution" in the context of biological speciation.[30] ... what were thought to be his remains were transported to Transylvania University and reinterred in a tomb under a stone ... Örstan, Aydin (2014). "Two early nineteenth-century uses of the term "evolution" to denote biological speciation". Archives of ...
Gigi II was another grey whale calf that was captured in the Ojo de Liebre Lagoon, and was transported to SeaWorld.[140] The ... Sonar interferes with the basic biological functions of whales-such as feeding and mating-by impacting their ability to ... This functions as an upward biological pump, reversing an earlier presumption that whales accelerate the loss of nutrients to ... This distinction is being questioned as these aboriginal groups are using more modern weaponry and mechanized transport to hunt ...
Biological Reviews. 78 (2): 251-345. doi:10.1017/S1464793102006103. PMID 12803423.. *^ a b Sahney, S., Benton, M.J. & Falcon- ... As amniotes, reptile eggs are surrounded by membranes for protection and transport, which adapt them to reproduction on dry ... "Proceedings of the Royal Society B: Biological Sciences. 274 (1610): 635-640. doi:10.1098/rspb.2006.3763. PMC 2197205. PMID ... Biological and Biomedical Sciences. 39 (3): 298-313. doi:10.1016/j.shpsc.2008.06.004. PMID 18761282.. ...
See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators ... function because the flexible side chains in these analogues do not have the conformations required for high biological ...
Transport phenomenaEdit. Main article: Transport phenomena. Modeling and analysis of transport phenomena is essential for many ... biological engineering, construction specification, and operating instructions. ... Transport phenomena involve fluid dynamics, heat transfer and mass transfer, which are governed mainly by momentum transfer, ... Bird, R. Byron; Stewart, Warren E.; Lightfoot, Edwin N. (2002), Kulek, Petrina (ed.), Transport Phenomena (2nd ed.), United ...
Grammar-based codes like this can compress highly repetitive input extremely effectively, for instance, a biological data ... A survey on data compression methods for biological sequences. Information 7(4):(2016): 56 ...
Biological classification * sw:Uainishaji wa kisayansi. Biological materials * sw:Biological materials. Biology * sw:Biology. ... Transport * sw:Usafiri. Treaty of Versailles * sw:Mkataba wa Versailles. Tree * sw:Mti. Trigonometry * sw:Trigonometry. ...
"Philosophical Transactions of the Royal Society B: Biological Sciences. 357 (1418): 133-142. doi:10.1098/rstb.2001.1024. PMC ... and is manufactured using a process and heat treatment that allows it to be transported and stored at ambient temperatures. ...
TransportEdit. Until recently, it was thought that the sole important retinoid delivery pathway to tissues involved retinol ... "The biological activity of retinotaurine". The Journal of Nutrition. 112 (8): 1626-30. PMID 7097369 ... "The multifaceted nature of retinoid transport and metabolism". Hepatobiliary Surgery and Nutrition. 3 (3): 126-39. doi:10.3978 ...
Scientific studies show that coarse woody debris can be a significant contributor to biological carbon sequestration. Trees ... To fulfill nutritional requirements of consumers, CWD must be first nutritionally enriched by transport of nutrients from ...
... nucleus to the cytoplasm is a critical component in a cells ability to make the proteins necessary for essential biological ... these discoveries have significant ramifications on our understanding of multiple biological questions including RNA transport ... "When we look at these transport granules to scale, we see that theyre too large to pass through the nuclear pore complex," ... Scientists shed light on biological roots of individuality. February 16, 2018 Put 50 newborn worms in 50 separate containers, ...
This second Volume in the series on Membrane Transport in Biology contains a group of essays on transport across single ... biological membranes separating the inside and outside of cells or organelles. W ... second Volume in the series on Membrane Transport in Biology contains a group of essays on transport across single biological ... The transport of water between the inside and outside of cells and organelles is important for the function of these structures ...
It does not require a transport medium and can be used dry. The device may further include a sample inoculator to distribute ... Methods for collecting and transporting microbiological specimens and for recovering detectable antigen are also described. ... A microbiological culture collection and transport device maintains viable organisms for periods of time longer than possible ... Biological specimen collection and transport system and method of use. US8728414 *. May 14, 2010. May 20, 2014. Dna Genotek Inc ...
Multi-component biological transport systems. 2003-12-11. Waugh et al.. 20030220480. Cell-permeable peptide inhibitors of the ... Multi-component biological transport systems. 2004-11-04. Waugh et al.. 20040192754. Methods for treating idiopathic ... Method for enhancing transport across biological membranes. 2002-09-19. Rothbard et al.. ... Method and composition for enhancing transport across biological membranes. 2003-08-28. Rothbard et al.. ...
"Transport in Biological Media" is a solid resource of mathematical models for researchers across a broad range of scientific ... or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging ... It provides a wide range of biological and clinical applications. It includes physiological descriptions of models. ... Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling ...
Purchase The Mechanism of gated calcium Transport across Biological Membranes - 1st Edition. Print Book & E-Book. ISBN ... The Mechanism of gated calcium Transport across Biological Membranes 1st Edition. Write a review ... The Mechanism of Gated Calcium Transport Across Biological Membranes presents the proceedings of a symposium, which was an ... Section 1: Gated Calcium Transport in Various Tissues. General Properties of Gated Calcium Transport. Development of Ca ...
Biological transport, Active. Chloride cells. Chlorides. Chlorides - Metabolism. Epithelium. Membranes (Biology). Science / ... Chloride transport coupling in biological membranes and epithelia. George A. Gerencser. Snippet view - 1984. ... absorption acetazolamide acid Acta active transport addition Ahearn allosteric anion apical membrane Aplysia californica ATPase ... gb-gplus-shareChloride transport coupling in biological membranes and epithelia. ...
9780131569881 Our cheapest price for Transport Phenomena in Biological Systems is $123.86. Free shipping on all orders over $ ... Transport Phenomena in Biological Systems. by Truskey, George A.; Yuan, Fan; Katz, David F. *ISBN13: 9780131569881. ... Oxygen Transport from the Lungs to the Tissues. Ligand-Receptor Kinetics on the Cell Surface and Molecular Transport within ... mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.For ...
... (BOK) George A. Truskey, Fan Yuan, David F. Katz Del ... this text provides students with the skills necessary to develop and critically analyze models of biological transport and ... It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by ... Presenting engineering fundamentals and biological applications in a unified way, ...
Purchase Molecular Mechanisms of Water Transport Across Biological Membranes, Volume 215 - 1st Edition. Print Book & E-Book. ... Molecular Mechanisms of Water Transport Across Biological Membranes, Volume 215 1st Edition. ... He has edited numerous books and written some 180 papers on various aspects of membrane transport and especially transport ... Passive Water Transport in Biological Pores Cell Volume Homeostasis: Ionic and Nonionic Mechanisms Cotransporteres as Milecular ...
Buy Transport Across Single Biological Membranes by D. C. Tosteson from Waterstones today! Click and Collect from your local ... Transport Across Single Biological Membranes - Membrane Transport in Biology 2 (Paperback). D. C. Tosteson (editor) Sign in to ... second Volume in the series on Membrane Transport in Biology contains a group of essays on transport across single biological ... The transport of water between the inside and outside of cells and organelles is important for the function of these structures ...
New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a ... New insight into a central biological dogma on ion transport. Aarhus University ... transport, while ion pumps mediate slow and active uphill transport against an electrochemical gradient. Both processes are ... new-insight-into-a-central-biological-dogma-on-ion-transport/. Related Journal Article. http://dx.. doi.. org/. 10.. 1038/ ...
Published Article: Biological electron transport goes the extra mile. This content will become publicly available on November ...
Physicists Reveal Quantum Effects in Biological Oxygen Transport. 17th July 2014. Physicists have created a unique combination ... All animals must transport such molecules through the blood stream to where they are needed around their bodies, and myoglobin ... applied them to a previously well characterised protein found in muscle to develop a new picture of how biomolecules transport ...
It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. ... Binding, Transport and Storage of Metal Ions in Biological Cells Editors: Wolfgang Maret, Anthony Wedd ... It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. ... His long term interests have been in polyoxometalate cluster chemistry and in biological inorganic chemistry, and particularly ...
Possible Role of Chelation between Alkali Metals and Pyridoxal in Biological Transport ... Possible Role of Chelation between Alkali Metals and Pyridoxal in Biological Transport ... Possible Role of Chelation between Alkali Metals and Pyridoxal in Biological Transport ... Possible Role of Chelation between Alkali Metals and Pyridoxal in Biological Transport ...
Division of Chemical, Biological, Environmental and Transport Systems. Directorate for Engineering. National Science Foundation ... The Division of Chemical, Biological, Environmental and Transport Systems seeks applicants for the following program:. * ... The Division for the Chemical, Biological, Environmental, and Transport Systems (CBET), within the Directorate for Engineering ... Dear Colleague Letter: Directorate for Engineering (ENG), Division of Chemical, Biological, Environmental, and Transport ...
The Process Separations Program in the Division of Chemical, Biological, Environmental, and Transport Systems (CBET) has, as of ... Dear Colleague Letter: Removal of Deadlines for the Process Separations Program in the Division of Chemical, Biological, ... Only proposals submitted to the Process Separations Program in the Division of Chemical, Biological, Environmental, and ... Transport Systems (CBET) are affected by this change. All other submissions to other programs or other funding opportunities ...
Actinides in Biological Systems. Gerhard Geipel and Katrin Viehweger Actinides are radioactive heavy elements with atomic ... Therefore, for these elements redox reactions in biological systems are of great significance. Actinides can accumulate in the ... Therefore, no information about their behaviour in biological systems has been published until recently. Especially uranium, ...
Anion transport in the colon Message Subject (Your Name) has sent you a message from Philosophical Transactions of the Royal ... The principal anions transported by colonic epithelium are Cl-, HCO-3 and organic anions (OA-), particularly acetate, butyrate ... In the normal absorptive rat colon, Cl- is transported from lumen to plasma both by the transcellular and paracellular pathways ... Your Name) thought you would like to see the Philosophical Transactions of the Royal Society B: Biological Sciences web site. ...
... and note that similar energy considerations have been used in the study of other biological transport systems [23,30-32]. For ... 2011 Symplasmic transport and phloem loading in gymnosperm leaves. Protoplasma 248, 181-190. (doi:10.1007/s00709-010-0239-0). ... 2014 Phloem transport and drought. J. Exp. Bot. 65, 1751-1759. (doi:10.1093/jxb/ert467). ... 2003 Water transport in plants obeys Murrays law. Nature 421, 939-942. (doi:10.1038/nature01444). ...
Nonequilibrium Thermodynamics: Transport And Rate Processes In Physical, Chemical And Biological…. byYasar DemirelEditorYasar ... Coupled Systems of Chemical Reactions and Transport Processes 10. Membrane Transport 11. Thermodynamics and Biological Systems ... Title:Nonequilibrium Thermodynamics: Transport And Rate Processes In Physical, Chemical And Biological…Format:Hardcover ... Customer Reviews of Nonequilibrium Thermodynamics: Transport And Rate Processes In Physical, Chemical And Biological Systems. ...
Home » Research » Projects » Biological Chemistry: Metal transport by proteins. Biological Chemistry: Metal transport by ... To overcome this paradox, living systems have developed elaborate metal-transport systems that appear to involve unique ... zinc and manganese transport proteins, for which less is known, and to (2) in vivo conditions exploring diseases related to ... the first goal is to design a plan to extend already successful in vitro biophysical research on copper transport proteins to ( ...
Biological pores are responsible for the transport of various ions and substrates between the different compartments of ... biological systems separated by membranes while artificial pores are aimed at emulating such transport properties. The aim of ... With this seminar we would like to bridge gaps and search for common ways on how to elucidate mechanisms of molecular transport ... M. Wanunu, Northeastern University Boston/USASeminarbericht Scope Nanoscale pores and channels are ubiquitous in biological ...
Your Name) thought you would like to see the Philosophical Transactions of the Royal Society B: Biological Sciences web site. ... Ionic transport mechanisms underlying fluid secretion by the pancreas Message Subject (Your Name) has sent you a message from ... Ionic transport mechanisms underlying fluid secretion by the pancreas. T. Scratcherd, D. Hutson, R. M. Case ... Thank you for your interest in spreading the word on Philosophical Transactions of the Royal Society B: Biological Sciences. ...
There are two basic mechanisms for biological transport: passive diffusion and motor-driven active transport. This thesis ... "Stochastic Modeling of Dynamical Processes in Biological Signaling and Cellular Transport." (2016) Diss., Rice University. ... In the case of active transport, we investigate the fundamental role of local interactions between molecular motors by ... Successful cellular function and organ development rely on the effective transport of proteins and other biomolecules to ...
Biological and Environmental Transport Process which is a required course for junior and senior students where the students ... Biological and Environmental Transport Process which is a required course for junior and senior students where the students ... AGEN/BSEN 344: Biological and Environmental Transport Processes-A Peer Review of Teaching Project Benchmark Portfolio ...
The aim of the investigations was to evaluate benefits of the directed transport system - a nanocomposite, based on cisplatin ... "Evaluation of Biological Effects of Nanosystems of Directed Transport in Experiments in Vivo and Their Application ... Pharmacokinetics and Biological Effects of Ferromagnetic Nanocomposite in Rats with Sensitive and Ddp-Resistant Guerins ...
Transport of carbon and phosphorus compounds about Sphagnum Message Subject (Your Name) has sent you a message from Proceedings ... Transport of carbon and phosphorus compounds about Sphagnum. H. Rydin, R. S. Clymo ... Your Name) thought you would like to see the Proceedings of the Royal Society of London B: Biological Sciences web site. ... Thank you for your interest in spreading the word on Proceedings of the Royal Society of London B: Biological Sciences. ...
... ... Multi-particle non-equilibrium dynamics in two-channel biological transport systems is investigated theoretically within the ... The third model considers junction of two parallel tracks, while the last model investigates two-way transport system with ... The first two models investigate interchannel coupling between parallel channels in a one-way transport system. ...
Mathematics of Biological Charge Transport: Molecules and Beyond. July 20 - 24, 2015 ... This brings us to the second and technical focus of our workshop, charge transport. The simplest model of charge transport is ... Charge transport has seen a resurgence in interest due partly to its central role in mathematical molecular biology and has ... Biological Solutions are Not Ideal: A Fermi Treatment. Robert Eisenberg (Rush University) ...
  • We aim for a holistic molecular description how specific lipids regulate transport of ions, nutrients and compatible solutes across cell membranes and between chemically distinct organelles. (uni-regensburg.de)
  • Three different mechanisms for passive transport in bilayer membranes. (diffen.com)
  • Active and passive transport are biological processes that move oxygen , water and nutrients into cells and remove waste products. (diffen.com)
  • The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cell's ability to make the proteins necessary for essential biological functions. (phys.org)
  • Found along the surface of the nuclear envelope, nuclear pores are small openings that allow certain molecules, such as messenger RNA, transfer RNA and ribosomes , to be transported across this physical barrier that separates a cell's nucleus and DNA from its cytoplasm. (phys.org)
  • Examples of active transport include a sodium pump, glucose selection in the intestines, and the uptake of mineral ions by plant roots. (diffen.com)
  • By solving atomic structures of individual transporters and channels in their native membrane environment and in complex with regulatory proteins in combination with functional measurements and spectroscopy we want to determine a molecular movie of lipid-mediated transport regulation. (uni-regensburg.de)
  • In some cells, these RNAs are bound together in large clusters known as transport granules, which are carried to precise locations within a cell to synthetize specific proteins needed at that site. (phys.org)
  • Working to understand how synapses develop and communicate with neighboring muscle cells, Budnik discovered a new method whereby these large granules, in the form of ribonucleoprotein (RNP) particles, were transported across the nuclear envelope. (phys.org)
  • In eukaryotic cells , amino acids, sugars and lipids need to enter the cell by protein pumps, which require active transport.These items either cannot diffuse or diffuse too slowly for survival. (diffen.com)
  • Transport occurs from a low concentration of solute to high concentration of solute. (diffen.com)
  • In addition to the canonical pathway of mRNA export going through the nuclear pore complex , we now know that large RNA transport granules can be assembled in the cell nucleus and exported via a budding mechanism previously thought to only be used by the herpes virus. (phys.org)
  • Cancer employs mass transport as a fundamental mechanism of coordination and communication and the physics of mass transport within body compartments and across biological barriers differentiates cancer from healthy tissues [3]. (nyu.edu)
  • Mass transport is also at the basis of cancer pharmacological treatment Delivery of diagnostic and therapeutic agents differs dramatically between tumor and normal tissues. (nyu.edu)
  • Passive transport occurs in the kidneys and the liver, and in the alveoli of the lungs when they exchange oxygen and carbon dioxide. (diffen.com)
  • 3] Baxter, L.T., Jain, R.K. Transport of fluid and macromolecules in tumors. (nyu.edu)
  • Active transport requires chemical energy because it is the movement of biochemicals from areas of lower concentration to areas of higher concentration. (diffen.com)
  • Active Transport uses ATP to pump molecules AGAINST/UP the concentration gradient. (diffen.com)
  • There are two types of active transport: primary and secondary. (diffen.com)
  • In primary active transport, specialized trans-membrane proteins recognize the presence of a substance that needs to be transported and serve as pumps, powered by the chemical energy ATP, to carry the desired biochemicals across. (diffen.com)
  • In secondary active transport, pore-forming proteins form channels in the cell membrane and force the biochemicals across using an electromagnetic gradient. (diffen.com)
  • Example of primary active transport , where energy from hydrolysis of ATP is directly coupled to the movement of a specific substance across a membrane independent of any other species. (diffen.com)
  • Reduced models of flow or mass transport in heterogeneous media are often adopted in the computational approach when the geometrical configuration of the system at hand is too complex. (nyu.edu)
  • Transports molecules through the cell membrane against the concentration gradient so more of the substance is inside the cell (i.e. a nutrient) or outside the cell (i.e. a waste) than normal. (diffen.com)
  • Four chapters describe transport of different types of molecules and ions across the plasma membranes of mammalian red cells. (springer.com)
  • All animals must transport such molecules through the blood stream to where they are needed around their bodies, and myoglobin is particularly important in vertebrates. (tcd.ie)
  • The phloem vascular system facilitates transport of energy-rich sugar and signalling molecules in plants, thus permitting long-range communication within the organism and growth of non-photosynthesizing organs such as roots and fruits. (royalsocietypublishing.org)
  • The phloem is a complex distribution system responsible for transporting a large number of organic molecules, defensive compounds and developmental signals by bulk fluid flow through a network of elongated sieve element cells which are connected to each other by porous sieve plates, effectively forming long tubes [ 1 ]. (royalsocietypublishing.org)
  • In the matter of passive diffusion, we investigate fundamental processes of biological development that are governed by multiple signaling molecules that create non-uniform concentration profiles known as morphogen gradients. (rice.edu)
  • Such transport typically occurs in cell membranes, which are thought to contain carriers which move molecules from one side of the membrane to the other. (thefreedictionary.com)
  • A process by which particles (e.g. ions, molecules) are transported across cell membranes, against, in almost all instances, the concentration gradient. (thefreedictionary.com)
  • In Biological Engineering, there are faculty studying the exclusion or passage of molecules through mucus barriers and other transport phenomena-related projects. (mit.edu)
  • Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins. (wikipedia.org)
  • Hence, small polar molecules are transported by proteins in the form of transmembrane channels. (wikipedia.org)
  • Larger molecules are transported by transmembrane carrier proteins, such as permeases, that change their conformation as the molecules are carried across (e.g. glucose or amino acids). (wikipedia.org)
  • As a result of investigations in many laboratories over the past four decades, our picture of the water permea- bility of the red cell membranes is rather detailed when compared to the water permeability of other biological membranes. (springer.com)
  • The transport can be across cell membranes and epithelial layers. (rush.edu)
  • The study presented in this document is the result of three years of research into the complex world of Molecular Dynamics applied to biological cell membranes. (cranfield.ac.uk)
  • The results of the interaction of shock waves with biological cell membranes have been particularly satisfactory and they have opened a new line of investigation into cancer research. (cranfield.ac.uk)
  • With this seminar we would like to bridge gaps and search for common ways on how to elucidate mechanisms of molecular transport through nanopores and -channels. (we-heraeus-stiftung.de)
  • There are two basic mechanisms for biological transport: passive diffusion and motor-driven active transport. (rice.edu)
  • This project aims to understand the mechanisms that generate Ca2+ signals in flagella and how they act to regulate the transport of flagellar proteins. (mba.ac.uk)
  • Since there are some uncertain factors in the fermentation, especially the transport mechanisms of 1,3-PD across cell membrane, the metabolic network contains multiple possible metabolic systems. (springer.com)
  • Zhang YD, Feng EM, Xiu ZL (2011) Robust analysis of hybrid dynamical system for 1,3-propanediol transport mechanisms in microbial continuous fermentation. (springer.com)
  • summarize the current knowledge on the molecular mechanisms underlying the short and long term regulation of water channels (AQPs) in principal cells, fluid transport by leaky epithelia and cotransporters of the symport type which behave as molecular water pumps. (mexmat.ru)
  • The regulation of sterol distribution between various membranes within the cell, and mechanisms behind specific intracellular sterol transport remain poorly understood. (oatd.org)
  • These recent advances, however, have not been matched with process-oriented studies addressing circulation and behavioral processes at the appropriate temporal and spatial scales, and only a few larval transport mechanisms have been considered for near shore open coastlines. (bco-dmo.org)
  • Results from this study will have important ecological implications as wave circulation / Stokes drift and internal motions may represent critical and regular transport mechanisms for larvae of marine organisms that must return to near shore habitats to complete their life cycle, thereby impacting population connectivity and management strategies used by coastal planners (e.g., ecosystem-based fisheries management, placement of Marine Protected Areas). (bco-dmo.org)
  • This second Volume in the series on Membrane Transport in Biology contains a group of essays on transport across single biological membranes separating the inside and outside of cells or organelles. (springer.com)
  • gain your firms to seek the buy Electrical Potentials in Biological Membrane on your nice feet. (emilysiy.com)
  • Negro Quakers help the ideal buy Electrical Potentials in Biological Membrane Transport 1981 to be the unusual activities within its new cancer to interest outfits, fostering toxicity accounts. (emilysiy.com)
  • Our complexities are somewhat nucleic and great buy Electrical Potentials in Biological has our l, at an Gene of 2 seminar system. (emilysiy.com)
  • provide buy Electrical Potentials in Biological Membrane Transport interest to explore your type or contact off your types? (emilysiy.com)
  • And I would have that you are this download electrical potentials in biological of the system as Just already discrete. (sokp.pl)
  • Choinka Szkolna So pushed by LiteSpeed Web ServerPlease participate walked that LiteSpeed Technologies Inc. Search the download electrical potentials in biological membrane transport of over 310 billion book proteins on the eco-efficiency. (sokp.pl)
  • Diecezjalny Konkurs dla uczniów szkół specjalnych There must let another download electrical potentials in biological out of not, extremely, ' Astro wrenched. (sokp.pl)
  • Wielka Orkiestra w Zespole Szkół Specjalnych The download electrical potentials in biological membrane is right discussed. (sokp.pl)
  • Spotkanie u Biskupa download electrical potentials in biological DM:( second) books for your theme the copilot who told into step: the( not) terrific introduction of my invalid CycD Helge and for the useless policy. (sokp.pl)
  • Two essays concern the excitable membranes of nerve and muscle cells while the remaining four chapters treat transport across several types of intracellular membranes. (springer.com)
  • The process of maintaining these normal differences in electrolytic composition between the intracellular and extracellular fluids is active transport. (thefreedictionary.com)
  • Furthermore, proper intracellular transport via the endosomal trafficking system is crucial to maintain steady-state BDNF signaling. (escholarship.org)
  • Role of PGRMC1 in intracellular sterol transport . (oatd.org)
  • In this dissertation I describe my work with a putative progesterone binding protein, PGRMCl, and detail a novel role for this protein in intracellular sterol transport . (oatd.org)
  • In Chapter 1 I review what is currently known about regulation of cholesterol homeostasis and intracellular sterol transport . (oatd.org)
  • New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families. (eurekalert.org)
  • Physicists have created a unique combination of computer models, based on the theory of quantum mechanics, and applied them to a previously well characterised protein found in muscle to develop a new picture of how biomolecules transport and store oxygen (O2). (tcd.ie)
  • p>This section provides any useful information about the protein, mostly biological knowledge. (uniprot.org)
  • the transport relies on molecular binding between the cargo and the membrane-embedded channel or carrier protein. (wikipedia.org)
  • They are transported through aqueous compartments of cells or through extracellular space by water-soluble carriers (e.g. retinol binding protein). (wikipedia.org)
  • Characterization of the suitability of various grades of Hytrel™ polymer tubing for EMB applications was undertaken based on polymer water content, molecular transport/retention, and thermodynamic affinity for a range of putative HFW components including acids, bases, salts, organic acids and other organic species. (queensu.ca)
  • Presenting engineering fundamentals and biological applications in a unified way, this book provides learners with the skills necessary to develop and critically analyze models of biological transport and reaction processes.It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.For researchers in biomedical engineering. (ecampus.com)
  • Presenting engineering fundamentals and biological applications in a unified way, this text provides students with the skills necessary to develop and critically analyze models of biological transport and reaction processes. (platekompaniet.no)
  • Looking of readers, Bend you for reading the view Principles and Models of Biological Transport a greener, leafier tutorial by email on work. (palmtennis.com)
  • Polyethylene glycols (PEGs) can improve the diffusivity of nanoparticles (NPs) in biological hydrogels, while extended PEG chains severely impede cellular uptake of NPs. (sciencemag.org)
  • Describes the need to obtain an import or export permit prior to the shipment of infectious substances and related biological substances, and/or materials that may contain infectious substances into or out of the country. (citiprogram.org)
  • Provides several lists of regulated biological materials including an example list of Category A Infectious Substances, a list of select agents, and the U.S. Department of Commerce (DOC) Commerce Control List (CCL). (citiprogram.org)
  • The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. (rush.edu)
  • The Packaging Requirement for Biological Substances and Hazardous Materials document provides information about packaging hazardous substances and materials for shipment. (umich.edu)
  • It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems. (platekompaniet.no)
  • The in- tention is to stress the close relationship between bioosmotic (transport) and biochemical processes in metabolism. (waterstones.com)
  • The in- tention is to emphasize the shut courting among bioosmotic (transport) and biochemical strategies in metabolism. (rockridgebrothers.com)
  • The simplest model of charge transport is the Poisson-Nernst-Planck system, a classical model whose mathematical properties are still not well-understood and still poses difficult computational challenges. (umn.edu)
  • Natural phenomena consist of simultaneously occurring transport processes and chemical reactions. (indigo.ca)
  • Active transport operates against gradients of chemical concentration, electrical charge or electrochemical state. (thefreedictionary.com)
  • 3DFATMIC simulates subsurface flow, transport, and fate of contaminants which are undergoing chemical and/or biological transformations (microbes). (scisoftware.com)
  • The processes governing the distribution of chemical and microbe concentration and temperature include: (1) reversible sorption, (2) microbe-chemical interaction, and (3) hydrological transport by flow advection/convection, dispersion/diffusion, and effect of unsaturation. (scisoftware.com)
  • Biological membranes outline the boundaries of cells and compartmentalize the chemical and bodily processes required for all times. (data-transport.com)
  • One could provide download ion transport through with Foot that she asks settling an design from chemical by living that what is often basic maintains Advanced. (kevinmbuck.com)
  • This course fulfills the requirements for: Shipping biological materials that contain small volumes of chemical preservatives such as ethanol or formalin. (umich.edu)
  • This book deals with energetics of transport processes, largely expressed in terms of the thermodynamics of irreversible pro- cesses. (waterstones.com)
  • This minimal model predicts a power law phloem distribution consistent with transport energy minimization, suggesting that energetics are more important than translocation speed at the leaf level. (royalsocietypublishing.org)
  • Mechanics and Energetics of Biological Transport by Prof. Dr. Erich Heinz (auth. (rockridgebrothers.com)
  • on 2017 download mechanics and energetics of biological transport 1978 powers will do you focus what you are reflecting for on Usenet. (cook-inseln.net)
  • Your download mechanics and energetics of biological transport read an alternative permission. (cook-inseln.net)
  • The course is designed to meet requirements of the International Air Transport Association (IATA) and the U.S. Department of Transportation (DOT). (citiprogram.org)
  • Discusses the packaging criteria to ensure compliance with the major requirements of the U.S. Department of Transportation (DOT), International Air Transport Association (IATA), and the U.S. Postal Service. (citiprogram.org)
  • One 'pump-like' subunit creates the energy input (similar to a motor), while a 'channel-like' subunit has been re-purposed to function as an active carrier mediating transport of potassium against a 10,000 fold gradient. (eurekalert.org)
  • It serves two biological functions: a site of redox reactions and a mechanical linkage that allows proteins to retain their three-dimensional structure . (wikipedia.org)
  • High water content polymers (=30% equilibrated water) were able to transport ionic species, facilitating the rapid transport of monovalent salts, while low water content polymers did not. (queensu.ca)
  • BioWater Technology is a company focusing on development of sales of innovative technologies and solutions for biological treatment of water and wastewater. (environmental-expert.com)
  • BRANNOCK M, HOWES T, JOHNS M, De Clercq B, KELLER J. CFD modelling of particle transport and biological reactors in a mixed wastewater treatment vessel. (ugent.be)
  • This hostile wastewater was circulated through the polymeric tubing, selectively transporting the organic compounds through the membrane for biological degradation by an enriched bacterial consortium. (queensu.ca)
  • As the majority of cellular cholesterol resides in the plasma membrane and membrane derived vesicles, regulation of cholesterol homeostasis depends upon the transport of sterols from the plasma membrane to the endoplasmic reticulum. (oatd.org)
  • This study addresses near shore cross-shore larval transport processes that operate over wide geographic areas in open coast settings, namely larval transport by wave circulation / Stokes drift, and by internal tidal bores. (bco-dmo.org)
  • Larval transport by wave circulation / Stokes drift is a ubiquitous process that has not been studied observationally, and it is not known how internal tidal bores deliver larvae to intertidal habitats. (bco-dmo.org)
  • Recent studies suggest that larval transport in the near shore zone plays a central role in larval dispersal and connectivity of shallow water species. (bco-dmo.org)
  • Recent advances in our understanding of hydrodynamic processes driving cross-shore flows and growing awareness of the importance of the processes to larval transport, however, make this study timely. (bco-dmo.org)
  • To warrant the self-contained structure of the volume, two preparatory chapters are included of which the first is on equilibrium thermodynamics and the second on transport and rate processes. (asme.org)
  • Finally this extended model highlight the promising usefulness of the biological activity in prediction more accurate results and promote the assessment of biological activity on the marine system. (utwente.nl)
  • The equations (a set of PDEs) of transport and fate of chemicals and microbes are derived based on the principle of conservation of mass and the hypothesis of Monod kinetics. (scisoftware.com)
  • Chintha C Handapangoda, Malin Premaratne, David M Paganin, and Priyantha R D S Hendahewa, "Technique for handling wave propagation specific effects in biological tissue: Mapping of the photon transport equation to Maxwell's equations," Opt. (osapublishing.org)
  • A novel algorithm for mapping the photon transport equation (PTE) to Maxwell's equations is presented. (osapublishing.org)
  • The mapping of the PTE to Maxwell's equations is required to model wave propagation through foreign structures implanted in biological tissue for sensing and characterization of tissue properties. (osapublishing.org)
  • Some complete sets of fundamental equations for the analyses of the transport phenomena fulfilling basic physical laws are derived in the article. (iospress.com)
  • In this project, the first goal is to design a plan to extend already successful in vitro biophysical research on copper transport proteins to (1) zinc and manganese transport proteins, for which less is known, and to (2) in vivo conditions exploring diseases related to problems with metal transport. (stias.ac.za)
  • Successful cellular function and organ development rely on the effective transport of proteins and other biomolecules to specific positions. (rice.edu)
  • Their transport must therefore be "facilitated" by proteins that span the membrane and provide an alternative route or bypass mechanism. (wikipedia.org)
  • The first two models investigate interchannel coupling between parallel channels in a one-way transport system. (rice.edu)
  • The third model considers junction of two parallel tracks, while the last model investigates two-way transport system with narrow entrances with coupling on the boundaries. (rice.edu)
  • BDNF endosomal transport is a key signaling system facilitating many aspects of healthy brain function and synaptic plasticity. (escholarship.org)
  • This transport system, which is highly specific for cystine and glutamate, increases the concentration of cystine inside the cell. (wikipedia.org)
  • In this system, the anionic form of cystine is transported in exchange for glutamate. (wikipedia.org)
  • The aim of this WE-Heraeus seminar is to bring together scientists working synthetic and biological nanopores and -channel both from theory and experiment. (we-heraeus-stiftung.de)
  • Fluctuation-driven transport in biological nanopores. (mendeley.com)
  • Chapter 2 is on transport and rate processes. (asme.org)
  • The Tranzport™ Hood is designed with mesh netting and bacteria-filtering fabric to restrict the spread of biological contaminants by the subject while still ensuring full visibility and breathability. (gtdist.com)
  • An EMB utilizing Hytrel™ 3548 tubing was employed for the biological treatment of frequently occurring, representative hydrophilic and hydrophobic organic contaminants at hyper-saline salt concentrations. (queensu.ca)
  • Epithelial transport physiology, George A. Gerencser (ed. (edu.au)
  • Ion channels mediate fast and passive 'downhill' transport, while ion pumps mediate slow and active 'uphill' transport against an electrochemical gradient. (eurekalert.org)
  • in active transport, movement takes place against an electrochemical gradient. (thefreedictionary.com)
  • This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients. (uniprot.org)
  • The newcomer to modeling and/or COMSOL can use the Case Studies in this book to self-learn modeling in biological/biomedical applications. (comsol.es)
  • Biological and Environmental Transport Process which is a required course for junior and senior students where the students already took considerable number of courses in their major. (unl.edu)
  • We have developed techniques to image Ca2+ in both the cytosol and the flagella of Chlamydomonas and have recently demonstrated that intraflagellar Ca2+ elevations regulate the important process of intraflagellar transport (IFT) (Collingridge et al, 2013). (mba.ac.uk)
  • Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport. (zfin.org)
  • An even lovable download ion transport through biological membranes an integrated theoretical groupings in the will commonly serve well if a main program of approaches speech, which is the process stars less innovative to be a metalworking on absurd costumes. (kevinmbuck.com)
  • Biological transport is a key step of your quality process-the integrity of previous sampling phases and/or later analysis phases depends on it. (mappingcontrol.com)
  • 2. Graphically represent simple diffusion, facilitated diffusion and active transport. (coursehero.com)
  • Do the same for facilitated diffusion and active transport (use the range of O degrees to 80 degrees C.). 2. (coursehero.com)
  • Distinguish among the types of transport (simple diffusion, facilitated diffusion, and active transport), based on their kinetics and energy requirements. (gatech.edu)
  • The temperature dependence of facilitated transport is substantially different due to the presence of an activated binding event, as compared to free diffusion where the dependence on temperature is mild. (wikipedia.org)
  • Discusses the need for general security awareness training for all employees handling hazardous materials in the transport chain. (citiprogram.org)
  • Describes the need for all employees involved in the hazardous materials transport chain to be aware of the initial emergency response procedures and whom to notify in the event of an incident. (citiprogram.org)
  • Comparison of the biological actions of three purified heat-stable enterotoxins: effects on ion transport and guanylate cyclase activity in rabbit ileum in vitro. (asm.org)
  • Utilizing a specialized microfluidic isolation chamber for in vitro primary neuronal cultures, we demonstrate that Aβ oligomers compromise BDNF retrograde transport by impairing endosomal transport rate, resulting in impaired downstream signaling driven by BDNF. (escholarship.org)
  • Many experiments have now shown that double helical DNA can serve as a conduit for efficient charge transport (CT) reactions over long distances in vitro. (elsevier.com)
  • Thus, considerations of charge transport are central to any serious attempt to link structure to function in molecular biology. (umn.edu)
  • Charge transport has seen a resurgence in interest due partly to its central role in mathematical molecular biology and has seen emergent applications in other fields in biology and related areas, such as soft condensed matter physics. (umn.edu)
  • In particular, it is important to develop effective computational methods for calculating the transport properties of polymers and complex-shaped particle aggregates arising in materials science and biology. (umn.edu)
  • The path-integration method is evidently a powerful tool for computing basic transport properties of complex-shaped objects and should find wide application in polymer science, nanotechnological applications and biology. (umn.edu)
  • This project will examine near shore (region between 20 m depth and intertidal) physical and biological processes that account for the delivery of larvae to adult habitats. (bco-dmo.org)
  • The investigators hypothesize that a series of physical and biological events results in the delivery of invertebrate larvae to the intertidal habitat. (bco-dmo.org)
  • It points to the possibility of air ow through a stable two-layered DPPC phospholipid structure either from a numerical or physical and biological point of view and the existence of an alveolar membrane at the end of the bronchial tubes. (cranfield.ac.uk)
  • Two options for the Lagrangian numerical scheme in the transport module which enable and disable the adapted zooming scheme. (scisoftware.com)
  • The biological activity was incorporated into the numerical model by adjusting physical parameters in the reference situation, which are the critical bed shear stress, erosion rates and settling velocity. (utwente.nl)
  • A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. (platekompaniet.no)
  • there you can provide appearing Kindle practitioners on your download ion transport through biological membranes an integrated theoretical approach, instructor, or someone - no Kindle category made. (kevinmbuck.com)