Biological therapy. Medical search

Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.

Drugs that are used to treat RHEUMATOID ARTHRITIS.

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Used in the manufacture of acetophenetidin.

Antibodies produced by a single clone of cells.

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.

Biologically active substances whose activities affect or play a role in the functioning of the immune system.

Drugs used to treat or prevent skin disorders or for the routine care of skin.

Inflammation of the joints of the SPINE, the intervertebral articulations.

Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.

Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

Antibodies obtained from a single clone of cells grown in mice or rats.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.

A type of schizophrenia characterized by abnormality of motor behavior which may involve particular forms of stupor, rigidity, excitement or inappropriate posture.

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.

Substances that reduce or suppress INFLAMMATION.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.

Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.

Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or ANTIGENS. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of DRUGS and RADIOISOTOPES in the CHEMOTHERAPY and RADIOIMMUNOTHERAPY of certain cancers.

Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.

Arthritis of children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.

Works about comparative studies to verify the effectiveness of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques determined in phase II studies. During these trials, patients are monitored closely by physicians to identify any adverse reactions from long-term use. These studies are performed on groups of patients large enough to identify clinically significant responses and usually last about three years. This concept includes phase III studies conducted in both the U.S. and in other countries.

The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.

Works about studies that are usually controlled to assess the effectiveness and dosage (if appropriate) of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques. These studies are performed on several hundred volunteers, including a limited number of patients with the target disease or disorder, and last about two years. This concept includes phase II studies conducted in both the U.S. and in other countries.

The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state. This process can be achieved to a certain extent by NUCLEAR TRANSFER TECHNIQUES, such as fusing somatic cell nuclei with enucleated pluripotent embryonic stem cells or enucleated totipotent oocytes. GENE EXPRESSION PROFILING of the fused hybrid cells is used to determine the degree of reprogramming. Dramatic results of nuclear reprogramming include the generation of cloned mammals, such as Dolly the sheep in 1997.

Tumors or cancer of the human BREAST.

Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)

One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.

Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.

In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.

Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.

A voluntary organization concerned with the prevention and treatment of cancer through education and research.

A general term for various neoplastic diseases of the lymphoid tissue.

Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.

The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

The number of PLATELETS per unit volume in a sample of venous BLOOD.

A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.

A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)

New treatment strategies for malignant gliomas. (1/231)

Although survival in patients with malignant gliomas remains limited, there is renewed optimism with the emergence of novel treatment strategies. Cytotoxic agents such as temozolomide and CPT-11 have shown promising clinical activity. Biological treatments for brain tumors, including antisense oligonucleotides, gene therapy, and angiogenesis inhibitors, are also being evaluated in clinical trials. Delivery strategies have been developed to overcome challenges presented by the blood-brain barrier. These noteworthy treatments, alone or in combination, may ultimately prolong survival and enhance quality of life in this group of patients. (+info)

Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. (2/231)

Genetically engineered, neuroattenuated herpes simplex viruses (HSVs) expressing various cytokines can improve survival when used in the treatment of experimental brain tumors. These attenuated viruses have both copies of gamma(1)34.5 deleted. Recently, we demonstrated increased survival of C57BL/6 mice bearing syngeneic GL-261 gliomas when treated with an engineered HSV expressing IL-4, as compared with treatment with the parent construct (gamma(1)34. 5(-)) alone or with a virus expressing IL-10. Herein, we report construction of a conditionally replication-competent mutant expressing both subunits of mIL-12 (M002) and its evaluation in a syngeneic neuroblastoma murine model. IL-12 induces a helper T cell subset type 1 response, which may induce more durable antitumor effects. In vitro studies showed that, when infected with M002, both Vero cells and murine Neuro-2a neuroblastoma cells produced physiologically relevant levels of IL-12 heterodimers, as determined by ELISA. M002 was cytotoxic for Neuro-2a cells and human glioma cell lines U251MG and D54MG. Neurotoxicity studies, as defined by plaque-forming units/LD(50), performed in HSV-1-sensitive A/J strain mice found that M002 was not toxic even at high doses. When evaluated in an intracranial syngeneic neuroblastoma murine model, median survival of M002-treated animals was significantly longer than the median survival of animals treated with R3659, the parent gamma(1)34.5(-) mutant lacking any cytokine gene insert. Immunohistochemical analysis of M002-treated tumors identified a pronounced influx of CD4(+) T cells and macrophages as well as CD8(+) cells when compared with an analysis of R3659-treated tumors. We conclude that M002 produced a survival benefit via oncolytic effects combined with immunologic effects meditated by helper T cells of subset type 1. (+info)

Where is biological therapy going? (3/231)

The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets and effector functions. These biologicals have greatly contributed to our current knowledge of pathogenetic mechanisms in autoimmune diseases. However, although some of the biologicals have been extremely successful in treating the symptoms of chronic inflammation, biological therapy has not yet met the expectations of permanently silencing the chronic immune response. In this commentary we discuss current concepts and future directions of biological therapy, and the potential usefulness of biologicals as a treatment of human autoimmune diseases in appropriate critical applications with the use of suitably designed agents. (+info)

Probiotic agents and infectious diseases: a modern perspective on a traditional therapy. (4/231)

There is an increasing scientific and commercial interest in the use of beneficial microorganisms, or "probiotics," for the prevention and treatment of disease. The microorganisms most frequently used as probiotic agents are lactic-acid bacteria such as Lactobacillus rhamnosus GG (LGG), which has been extensively studied in recent literature. Multiple mechanisms of action have been postulated, including lactose digestion, production of antimicrobial agents, competition for space or nutrients, and immunomodulation. We have reviewed recent studies of probiotics for the treatment and control of infectious diseases. Studies of pediatric diarrhea show substantial evidence of clinical benefits from probiotic therapy in patients with viral gastroenteritis, and data on LGG treatment for Clostridium difficile diarrhea appear promising. However, data to support use of probiotics for prevention of traveler's diarrhea are more limited. New research suggests potential applications in vaccine development and prevention of sexually transmitted diseases. Further studies are needed to take full advantage of this traditional medical approach and to apply it to the infectious diseases of the new millennium. (+info)

Update on the treatment of systemic lupus erythematosus: therapeutic highlights from the Sixth International Lupus Conference. (5/231)

The studies presented at the conference indicate that new therapeutic agents are effective for patients with SLE. Some of the agents (high dose cyclophosphamide) may be given to patients with refractory disease while others (low dose cyclophosphamide, and MMF) may be used as a first-line drug. The current data on biologic agents are still preliminary and their exact role in SLE needs to be determined. (+info)

The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced nonsmall cell lung carcinoma: potential for decreased toxicity and combination with biological therapy. (6/231)

BACKGROUND: Gemcitabine and vinorelbine are two of the most active third-generation agents for the treatment of advanced nonsmall cell lung carcinoma (NSCLC). The authors conducted a formal Phase II trial to evaluate the efficacy of this combination in both untreated and previously treated patients with Stage IIIB (with pleural effusion) or Stage IV NSCLC. METHODS: A total of 78 patients were treated on the current Phase II trial of front-line or second/third-line therapy with gemcitabine and vinorelbine in NSCLC. Eligible patients manifested either untreated disease (n = 42) or had received at least one but not more than two prior chemotherapy regimens (n = 36). The median age was 57.5 years (range, 33-79) with 57 men (73%) and 21 women (27%). The median performance status was one (range, one to two). The initial eight patients (four untreated and four previously treated) were treated at a previously established maximum tolerated dose of vinorelbine (30 mg/m(2)) and gemcitabine (1000 mg/m(2)) on Days 1, 8, and 15, with significant myelosuppression seen in five out of eight patients requiring dose omission in the first cycle. The next 70 patients received a reduced dose of vinorelbine (25 mg/m(2)) followed by gemcitabine (900 mg/m(2)) on Days 1, 8, and 15. RESULTS: Seventy eight patients were treated. Fifteen (36%) of the 42 evaluable patients who received front-line therapy had objective responses and 14 (33%) had stable disease. In the patients with prior treatment, 6 (17%) of 36 patients had partial response and 18 patients (50%) had stable disease. Median survival time for the previously untreated patient group was 10.1 months, with a one year survival of 43% and a two year survival rate of 32%. For the previously treated patients, the median survival time was 8.5 months, with a one year survival rate of 30%. Toxic effects were notable for significant myelosuppression, with > or =Grade 3 granulocytopenia seen in 55% of the patients on the untreated arm and 67% of the patients on the previously treated arm. Additionally, 9.5% and 13.9% (untreated and previously treated), respectively, of these patients experienced Grades 3 and 4 thrombocytopenia at some point in their treatment. A full dose delivery analysis showed that this myelosuppression resulted in Course 1, Day 15 skipped doses (even at the reduced dose level) in 42% of previously untreated patients and 47% of pretreated patients. Other side effects seen at Grades 3 and 4 in previously untreated and treated patients included anemia (9.5% and 2.8%), asthenia (4.8% and 5.5%), infection (14.3% and 5.6%), pain (9.5% and 19.4%), and pulmonary complications (4.8% and 13.8%). CONCLUSIONS: Gemcitabine/vinorelbine is an active, well-tolerated combination in both front-line and second/third-line therapy for Stage IIIB/IV NSCLC. The response rate, median survival rate, and one year survival rate compare favorably with platinum-based regimens. The toxicity profile of the gemcitabine/vinorelbine combination was quite favorable, with minimal Grade 3 and 4 toxic effects aside from granulocytopenia, which resulted in numerous Day 15 skipped doses but no significant febrile neutropenia or infection. The combination of gemcitabine and vinorelbine could be a useful regimen in standard clinical practice and has the potential for efficient combination with biologic/targeted therapy. Multiple randomized trials of this combination versus platinum combinations are now ongoing [corrected]. (+info)

Yoghurt biotherapy: contraindicated in immunosuppressed patients? (7/231)

A fatal case of Lactobacillus rhamnosus septicaemia after prolonged oral vancomycin for recalcitrant Clostridium difficile infection is reported. The patient was immunosuppressed with cyclophosphamide and steroids for Sjogren's syndrome. The administration of Lactobacillus spp as "biotherapy" may be hazardous in such circumstances. (+info)

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker. (8/231)

Live attenuated measles virus (MV-Edm) has potent oncolytic activity against myeloma xenografts in mice. Therapy of multiple myeloma, a disseminated plasma cell malignancy, would require systemic administration of the virus. Thus, the virus should ideally be targeted to infect only myeloma cells to minimize collateral damage to normal tissues: viral binding to its natural receptors must be ablated and a new specificity domain that targets entry into myeloma cells be added. This study covers 2 critical steps toward generating such a retargeted virus: (1) a new specificity domain against the plasma cell marker CD38 was constructed in the form of a single-chain antibody (scFv) and (2) display of that scFv on the measles viral envelope glycoprotein successfully redirected virus entry through CD38 expressed on target cells devoid of the natural MV receptors. The anti-CD38 scFv was tethered to the C-terminus of the hemagglutinin (H) glycoprotein of MV-Edm through a Factor Xa protease cleavable linker. Immunoblot analysis demonstrated that the scFv was efficiently incorporated into recombinant viral particles. Replication of MV-alpha CD38 was not hindered by the scFv, reaching titers comparable to MV-Edm. Chinese hamster ovary (CHO) cells were resistant to infection by MV-Edm and MV-alpha CD38. In contrast, CHO cells expressing CD38 became susceptible to infection by MV-alpha CD38 but not MV-Edm. Removal of the displayed scFv rendered MV-alpha CD38 noninfectious on CHO-CD38 cells. Tumorigenicity of CHO-CD38 cells in immunocompromised mice was significantly attenuated by MV-alpha CD38, resulting in enhanced survival of these mice compared with the control group. (+info)

Expert Opinion on Biological Therapy. 8 (12): 1955-62. doi:10.1517/14728220802517901. PMID 18990082.. ... "The Journal of Biological Chemistry. 265 (26): 15361-4. PMID 2394726.. *^ Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, ... "The Journal of Biological Chemistry. 269 (13): 9397-400. PMID 8144521.. *^ Wells WW, Xu DP, Yang YF, Rocque PA (September 1990 ... "The Journal of Biological Chemistry. 263 (33): 17205-8. PMID 3053703.. *^ Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton ...

https://en.wikipedia.org/wiki/Free_radical_scavenger

Hall, R. A.; Khromykh, A. A. (2004). "West Nile virus vaccines". Expert Opinion on Biological Therapy. 4 (8): 1295-1305. doi: ... Titball, R. W.; Williamson, E. D. (2004). "Yersinia pestis (plague) vaccines". Expert Opinion on Biological Therapy. 4 (6): 965 ... Expert Opinion on Biological Therapy. 10 (2): 179-190. doi:10.1517/14712590903379502. PMID 20088713.. ... A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent ...

https://en.wikipedia.org/wiki/List_of_vaccine_topics

Expert Opinion on Biological Therapy. 8 (12): 1955-62. doi:10.1517/14728220802517901. PMID 18990082. S2CID 74736842.. ... Inhaled acetylcysteine has been used for mucolytic ("mucus-dissolving") therapy in addition to other therapies in respiratory ... "Biological Psychiatry. 71 (11): 978-86. doi:10.1016/j.biopsych.2011.10.024. PMC 3340445. PMID 22137594.. ... Samuni Y, Goldstein S, Dean OM, Berk M (August 2013). "The chemistry and biological activities of N-acetylcysteine". Biochimica ...

https://en.wikipedia.org/wiki/N-Acetylcysteine

Reynolds, PN (February 2011). "Gene therapy for pulmonary hypertension: prospects and challenges". Expert Opinion on Biological ... Levels of cAMP (which mediates most of the biological effects of prostacyclin) are reduced by phosphodiesterases 3 and 4.[48][ ... The three pathways described above are all targeted by currently available medical therapies for PAH. However, several other ... For people that inherited the disease, gene therapy is being studied.[101] ...

https://en.wikipedia.org/wiki/Pulmonary_Hypertension

Expert Opinion on Biological Therapy. 12 (4): 395-410. doi:10.1517/14712598.2012.664129. PMID 22335323.. ... "International Journal of Biological Sciences. 6 (7): 834-844. doi:10.7150/ijbs.6.834. PMC 3005349. PMID 21179590.. ... "Discourses: Biological & Geological (volume VIII) : Yeast". Collected Essays. Retrieved 28 November 2009 ...

https://en.wikipedia.org/wiki/Budding_yeast

Eckstein, Fritz (2007). "The versatility of oligonucleotides as potential therapeutics". Expert Opinion on Biological Therapy. ... "Journal of Biological Physics. 33 (5-6): 345-356. doi:10.1007/s10867-008-9074-3. PMC 2565759. PMID 19669523.. ... "Molecular Therapy. 17 (1): 95-103. doi:10.1038/mt.2008.215. PMC 2834975. PMID 18957965.. ... A reevaluation of the mechanism of cellular uptake". The Journal of Biological Chemistry. 278 (1): 585-90. doi:10.1074/jbc. ...

https://en.wikipedia.org/wiki/Cell_penetrating_peptide

Expert Opinion on Biological Therapy. 7 (5): 599-615. doi:10.1517/14712598.7.5.599. PMID 17477799.. ... Anticancer therapy[edit]. Since NK cells recognize target cells when they express nonself HLA antigens (but not self), ... Smyth MJ, Hayakawa Y, Takeda K, Yagita H (November 2002). "New aspects of natural-killer-cell surveillance and therapy of ... respond better to antibody therapy. This has been shown for lymphoma patients who received the antibody Rituxan. Patients who ...

https://en.wikipedia.org/wiki/NK_cell

Expert Opinion on Biological Therapy. 13 (11): 1613-21. doi:10.1517/14712598.2013.840285. PMID 24088009.. ... Proceedings of the Royal Society B: Biological Sciences. 278 (1702): 42-49. doi:10.1098/rspb.2010.1107. PMC 2992723. PMID ...

https://en.wikipedia.org/wiki/Herd_immunity

Lima, X. T.; Abuabara, K.; Kimball, A. B.; Lima, H. C. (2009). "Briakinumab". Expert Opinion on Biological Therapy. 9 (8): 1107 ...

https://en.wikipedia.org/wiki/Briakinumab

Expert opinion on biological therapy. 10 (7): 1077-87. PMID 20455790. doi:10.1517/14712598.2010.487060.. ...

https://en.wikipedia.org/wiki/CYT006-AngQb

Expert Opinion on Biological Therapy. 18 (4): 369-379. doi:10.1080/14712598.2018.1421169. PMID 29285958.. ... A biopharmaceutical, also known as a biologic(al) medical product, biological,[1] or biologic, is any pharmaceutical drug ... Gene therapy[edit]. Viral gene therapy involves artificially manipulating a virus to include a desirable piece of genetic ... Some regulatory agencies use the terms biological medicinal products or therapeutic biological product to refer specifically to ...

https://en.wikipedia.org/wiki/Biologics

Expert Opinion on Biological Therapy. 15 (8): 1183-90. doi:10.1517/14712598.2015.1049943. PMID 26160491.. ... The authors stated "…the use of HCG should be regarded as an inappropriate therapy for weight reduction…" In the authors ... As the most abundant biological source is women who are presently pregnant, some organizations collect urine from pregnant ... Restraints on physicians practicing this therapy can be based on our findings." ...

https://en.wikipedia.org/wiki/Beta-HCG

Lundstrom, K. (2003). "Semliki Forest virus vectors for gene therapy". Expert Opinion on Biological Therapy. 3 (5): 771-777. ... Semliki Forest virus has been used extensively in biological research as a model of the viral life cycle and of viral ... "Alphavirus vectors for cancer therapy". Virus Research. 153 (2): 179-196. doi:10.1016/j.virusres.2010.07.027. PMID 20692305.. ... and as a tool in gene therapy.[8] ...

https://en.wikipedia.org/wiki/Semliki_Forest_virus

Graham, Lloyd D (2002). "Ecdysone-controlled expression of transgenes". Expert Opinion on Biological Therapy. 2 (5): 525-35. ... Although mammals lack this receptor, 20-hydroxyecdysone may affect mammalian (including human) biological systems in vitro, but ... For uses in gene therapy, it may be necessary to investigate more thoroughly the natural sources of ecdysteroids in humans ( ... This would explain the mechanism behind Helminthic therapy due to the production of ecdysteroids by helminths, as mentioned ...

https://en.wikipedia.org/wiki/20-Hydroxyecdysone

Expert Opinion on Biological Therapy. 18 (4): 369-379. doi:10.1080/14712598.2018.1421169. PMID 29285958.. ... Gene therapy[edit]. Viral gene therapy involves artificially manipulating a virus to include a desirable piece of genetic ... Some regulatory agencies use the terms biological medicinal products or therapeutic biological product to refer specifically to ... European Medicines Agency, "tooltip definition of advanced therapy medicinal products", Committee for Advanced Therapies (CAT) ...

https://en.wikipedia.org/wiki/Biologic_medical_product

Sulfasalazine, mesalazine, steroids, immunosuppressants such as azathioprine, biological therapy[1]. Frequency. 2-299 per ... Expert Opinion on Biological Therapy. 16 (4): 567-72. doi:10.1517/14712598.2016.1158807. PMID 26914639. S2CID 24706213.. ... "Promising biological therapies for ulcerative colitis: A review of the literature". World Journal of Gastrointestinal ... Helminthic therapy using the whipworm Trichuris suis has been shown in a randomized control trial from Iowa to show benefit in ...

https://en.wikipedia.org/wiki/Ulcerative_colitis

"Xolair - Biological Therapy". Drugdevelopment-technology.com. Leung DY, Sampson HA, Yunginger JW, et al. (2003). "Effect of ... Chang is a cofounder of Tanox, a biopharmaceutical company specialized in anti-IgE therapies for the treatment of allergic ... Chang TW, 2000, "The pharmacological basis of anti-IgE therapy." Nature Biotechnology, 18(2), 157-162. Chang TW and Shiung YY, ... anti-IgE therapy in patients with peanut allergy". N. Engl. J. Med. 348 (11): 986-93. doi:10.1056/NEJMoa022613. PMID 12637608. ...

https://en.wikipedia.org/wiki/Tse_Wen_Chang

Biological therapy for inflammatory bowel disease. References[edit]. *^ a b c d "Infliximab, Infliximab-dyyb Monograph for ... Maintenance therapy with the drug (versus intermittent or sporadic therapy) lessens the likelihood of developing antibodies to ... "Promising biological therapies for ulcerative colitis: A review of the literature". World Journal of Gastrointestinal ... Infliximab neutralizes the biological activity of TNF-α by binding with high affinity to the soluble (free floating in the ...

https://en.wikipedia.org/wiki/Remicade

Cheng JH, Wang CJ (2015). "Biological mechanism of shockwave in bone". International Journal of Surgery. 24: 143-6. doi:10.1016 ... Extracorporeal shockwave therapy (ESWT) is a treatment mostly used to treat kidney stones and in physical therapy and ... Extracorporeal shockwave therapy is used as a second line measure to treat tennis elbow,[9][10] shoulder rotator cuff pain,[11] ... Yin MC, Ye J, Yao M, Cui XJ, Xia Y, Shen QX, Tong ZY, Wu XQ, Ma JM, Mo W (2014). "Is extracorporeal shock wave therapy clinical ...

https://en.wikipedia.org/wiki/Lithotriptor

Taylor RW (February 2005). "Gene therapy for the treatment of mitochondrial DNA disorders". Expert Opinion on Biological ... Presently, gene therapy and nutraceutical supplementation are popular areas of ongoing research. Bjelakovic et al. analyzed the ... An IVF technique known as mitochondrial donation or mitochondrial replacement therapy (MRT) results in offspring containing ... The Journal of Biological Chemistry. 281 (1): 374-82. doi:10.1074/jbc.M509730200. PMID 16263719. Jemt E, Farge G, Bäckström S, ...

https://en.wikipedia.org/wiki/Mitochondrial_DNA

Expert Opinion on Biological Therapy. 15 (8): 1155-72. doi:10.1517/14712598.2015.1051527. PMC 4883659. PMID 26027436. Loh QL, ... Biological scaffolds can be created from human donor tissue or from animals; however, animal tissue is often more popular since ... Series B, Biological Sciences. 362 (1484): 1505-12. doi:10.1098/rstb.2007.2131. PMC 2440411. PMID 17588875. Gandaglia A, Bagno ... Studies led by Dohmen, Konertz, and colleagues in Berlin, Germany involved the implantation of a biological pig valve in 50 ...

https://en.wikipedia.org/wiki/Tissue_engineering_of_heart_valves

Goldstein, A.L. and Garaci, E., Combination Therapies: Biological Response Modifiers in the Treatment of Cancer and Infectious ... Expert Opinion on Biological Therapy. 18 (sup1): 77-83. doi:10.1080/14712598.2018.1494717. ISSN 1744-7682. OCLC 768086347. PMID ... Expert Opinion on Biological Therapy. 18 (sup1): 9-11. doi:10.1080/14712598.2018.1484447. ISSN 1471-2598. OCLC 644930062. PMID ... Goldstein's research has helped define the role of biological response modifiers in health and disease, and has led to the ...

https://en.wikipedia.org/wiki/Allan_L._Goldstein

Other treatment options include biological therapies such as everolimus, torisel, nexavar, sutent, and axitinib, the use of ... Treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy. Kidney cancer newly ... "Biological therapy for kidney cancer". 2017-08-30. Jonasch, Eric; Messner, Carolyn (August 2012). "CancerCare Connect - ... The utility of renal mass biopsy (RMB) lies in that it can confirm malignancy with reliability, can direct therapy based on ...

https://en.wikipedia.org/wiki/Kidney_cancer

Expert Opinion on Biological Therapy. 9 (5): 649-57. doi:10.1517/14712590902926071. PMID 19392579. Schubert-Zsilavecz, M, ...

https://en.wikipedia.org/wiki/Naproxcinod

Triozzi, PL; Borden, EC (December 2011). "VB-111 for cancer". Expert Opinion on Biological Therapy. 11 (12): 1669-76. doi: ... Ofranergene obadenovec, also known as VB-111, is an anti-angiogenic gene therapy. The vector is a non-replicating adenovirus 5 ...

https://en.wikipedia.org/wiki/Ofranergene_obadenovec

Expert Opinion on Biological Therapy. 7 (5): 713-26. doi:10.1517/14712598.7.5.713. PMID 17477808. S2CID 12725001. Pfeifer A, ... The CJD Therapy Advisory Group to the UK Health Departments advises that data are not sufficient to support claims that ... Series B, Biological Sciences. 356 (1406): 185-95. doi:10.1098/rstb.2000.0764. PMC 1088424. PMID 11260799. Ridley RM, Baker HF ... This research is unlikely to lead to a human therapy for many years. Both amphotericin B and doxorubicin have been investigated ...

https://en.wikipedia.org/wiki/Creutzfeldt–Jakob_disease

Trobridge, Grant D. (November 2009). "Foamy virus vectors for gene transfer". Expert Opinion on Biological Therapy. 9 (11): ... it may be a better vector for gene therapy than other foamy viruses. The budding characteristic of EFV from the plasma membrane ...

https://en.wikipedia.org/wiki/Equine_foamy_virus

Expert Opinion on Biological Therapy. 10 (2): 163-78. doi:10.1517/14712590903431022. PMC 2809805. PMID 19947897. "Anti-GD2 for ... It is given in patients who have completed induction therapy and consolidation therapy (autologous bone marrow transplant and ... external beam radiation therapy), as part of standard-of-care therapy for newly-diagnosed high-risk neuroblastoma. It is given ... Dinutuximab is used as post-consolidation therapy for children with high-risk neuroblastoma, in combination with granulocyte- ...

https://en.wikipedia.org/wiki/Dinutuximab

Expert Opinion on Biological Therapy. 20 (8): 831-836. doi:10.1080/14712598.2020.1767062. ISSN 1471-2598. PMID 32380868. S2CID ... a potential therapy agent for lung cancer". Cancer Gene Therapy. 17 (4): 256-65. doi:10.1038/cgt.2009.74. PMID 19893593. S2CID ... Nakamori M, Fu X, Meng F, Jin A, Tao L, Bast RC, Zhang X (July 2003). "Effective therapy of metastatic ovarian cancer with an ... Ilyinskaya GV, Mukhina EV, Soboleva AV, Matveeva OV, Chumakov PM (2018). "Oncolytic Sendai Virus Therapy of Canine Mast Cell ...

https://en.wikipedia.org/wiki/Murine_respirovirus

Expert Opinion on Biological Therapy. Informa UK Limited. 20 (9): 1061-1072. doi:10.1080/14712598.2020.1749259. ISSN 1471-2598 ... "New Drug Therapy Approvals 2020". U.S. Food and Drug Administration (FDA). 31 December 2020. Retrieved 17 January 2021. "Drug ... Clinical trial number NCT02028884 for "Efficacy and Safety Study of Satralizumab (SA237) as Add-on Therapy to Treat ...

https://en.wikipedia.org/wiki/Satralizumab

"Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas. 39 (8): 1065-70. ... Patients had to have CD4 cell counts less than 200 and at least 3 months of AZT therapy before the trials. 1156 patients with a ... It is normally used as one of the three drugs in a triple-combination therapy for the HIV virus.[1] ... is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS. It is soluble white ...

https://en.wikipedia.org/wiki/Indinavir

Examples include immuno-augmentation therapy, shark cartilage, bioresonance therapy, oxygen and ozone therapies, and insulin ... that has a biological or psychological effect on a patient may also have potential to possess dangerous biological or ... Prevalence of use of specific therapies. The most common CAM therapies used in the US in 2002 were prayer (45%), herbalism (19 ... The label "unproven" is inappropriate for such therapies; it is time to assert that many alternative cancer therapies have been ...

https://en.wikipedia.org/wiki/Integrative_medicine

"β-Catenin". Sino Biological Inc.: Biological Solution Specialist. Reynolds AB (June 2011). "Epithelial organization: new ... Recently, there have been a number of studies in the lab and in the clinic investigating new possible therapies for cancers ... Coluzzi F, Mandatori I, Mattia C (September 2011). "Emerging therapies in metastatic bone pain". Expert Opin Emerg Drugs. 16 (3 ...

https://en.wikipedia.org/wiki/Catenin

Berkowitz, S.A., Philo, J.S. Monitoring the Homogeneity of Adenovirus Preparations (a Gene Therapy Delivery System) Using ... Centrifugation in biological researchEdit. MicrocentrifugesEdit. Microcentrifuges are used to process small volumes of ... Ultracentrifugation makes use of high centrifugal force for studying properties of biological particles. Compared to ... biological molecules, cells, or nuclei. Microcentrifuge tubes generally hold 0.5 - 2.0 mL of liquid, and are spun at maximum ...

https://en.m.wikipedia.org/wiki/Centrifugation

... s are now produced synthetically and used as drugs in cancer therapy and as immunosuppressive drugs. These ... "Synthesis and biological evaluation of Vinca alkaloids and phomopsin hybrids". Journal of Medicinal Chemistry. 52 (1): 134-142 ...

https://en.wikipedia.org/wiki/Vinca_alkaloids

A Vital Legacy: Biological and Environmental Research in the Atomic Age, U.S. Department of Energy, The Office of Biological ... PET has an expanding role as a method to assess the response to therapy, in particular, cancer therapy,[57] where the risk to ... Psychiatry: Numerous compounds that bind selectively to neuroreceptors of interest in biological psychiatry have been ... Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy. Boca Raton: CRC Press. pp. 156-159.. ...

https://en.m.wikipedia.org/wiki/PET_scan

"Experimental therapies: growing interest in the use of whole blood or plasma from recovered Ebola patients (convalescent ... May 2002). "Hemorrhagic fever viruses as biological weapons: medical and public health management". Journal of the American ... It has the potential to be weaponised for use in biological warfare,[226][227] and was investigated by Biopreparat for such use ... This includes either oral rehydration therapy (drinking slightly sweetened and salty water) or giving intravenous fluids as ...

https://en.m.wikipedia.org/wiki/Ebola_virus_disease

These analyses may also prove useful in determining therapy and monitoring its efficacy."[1] ... Neural network (biological). *Detection theory. *Intraoperative neurophysiological monitoring. *Neurochip. *Neurodegeneration. ...

https://en.wikipedia.org/wiki/Neurometrics

"Arthritis Research & Therapy. 8 (3): R55. PMC 1526645. . PMID 16542493. doi:10.1186/ar1920. الوسيط ,السنة=. تم تجاهله (مساعدة ... a newly discovered member of the leucine-rich repeat protein family". The Journal of Biological Chemistry. 276 (15): 12212-21. ... a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan". The Journal of Biological ... The Journal of Biological Chemistry. 282 (44): 32193-9. PMID 17804408. doi:10.1074/jbc.M706262200. الوسيط ,التاريخ=. تم تجاهله ...

https://ar.wikipedia.org/wiki/Asporin

"The Journal of Biological Chemistry. 288 (7): 4878-90. doi:10.1074/jbc.M112.422410. PMC 3576092 . PMID 23275336.. ... Muñoz M, Rosso M, Coveñas R (Jun 2011). "The NK-1 receptor: a new target in cancer therapy". Current Drug Targets. 12 (6): 909- ... Unique among biological processes, SP release (and expression of its NK1 Receptor (through autocrine, paracrine, and endocrine- ... The Journal of Biological Chemistry. 279 (44): 45519-27. doi:10.1074/jbc.M408523200. PMID 15319441.. ...

https://en.m.wikipedia.org/wiki/Substance_P

In medicine, this era brought innovations such as open-heart surgery and later stem cell therapy along with new medications and ... including the possibility of the permanent alteration of our biological nature. These concerns are shared by other philosophers ...

https://en.m.wikipedia.org/wiki/Technological

Medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating ... Biomechanics is the study of the structure and function of biological systems by means of the methods of Mechanics. ... Biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. ... Histology is the study of the structures of biological tissues by light microscopy, electron microscopy and ...

https://en.wikipedia.org/wiki/Medical

Grissom RJ (1994). "Statistical analysis of ordinal categorical status after therapies". Journal of Consulting and Clinical ... Biological Reviews of the Cambridge Philosophical Society. 82 (4): 591-605. doi:10.1111/j.1469-185X.2007.00027.x. PMID 17944619 ...

https://en.wikipedia.org/wiki/Mann-Whitney_U_test

Normally, the bone age is the same as the biological age but for some people, it is older. For many people with advanced bone ... Allen DB (July 2006). "Growth hormone therapy for short stature: is the benefit worth the burden?". Pediatrics. 118 (1): 343-8 ...

https://en.wikipedia.org/wiki/Short_stature

"Progress in Clinical and Biological Research. 337 (7070): 301-7. doi:10.1136/bmj.313.7070.1450. PMC 2352989. PMID 8973234.. ... A forensic analysis of cigarettes made from diverted nicotine replacement therapy lozenges in smoke-free prisons". Drug Testing ... "Airborne exposure and biological monitoring of bar and restaurant workers before and after the introduction of a smoking ban". ...

https://en.wikipedia.org/wiki/Anti-smoking_legislation

In the past 15 years, students have raised over $5 million to support treatment, research, and various therapies at the ... Museum of Biological Diversity, National Center for the Middle Market, Stone Laboratory on Gibraltar Island, OH, Center for ... Biological Sciences Building, CDME, Comprehensive Cancer Center, David Heart and Lung Research Institute, Electroscience ... ", "Biological Sciences Scholars", "International Affairs Scholars", "Business Scholars" and "Politics, Society and Law ...

https://en.m.wikipedia.org/wiki/The_Ohio_State_University

Bianchi GE (1950). "[Penicillin therapy of lymphocytoma]" [Penicillin therapy of lymphocytoma]. Dermatologica (in German). 100 ... "Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas. 40 (4): 443-56. ... Newby, Kris (2019). Bitten: the Secret History of Lyme Disease and Biological Weapons. HarperCollins. ISBN 9780062896278. .. ... This hypothesis may explain why chronic arthritis persists after antibiotic therapy, similar to rheumatic fever, but its wider ...

https://en.wikipedia.org/wiki/Lyme_disease

Studies in History and Philosophy of Biological and Biomedical Sciences. 36 (1): 1-24. doi:10.1016/j.shpsc.2004.12.008.. ...

https://en.wikipedia.org/wiki/Earth_radiation

Biological activity[edit]. Androgens bind to and activate androgen receptors (ARs) to mediate most of their biological effects. ... For androgens as medications, see Anabolic steroid and Androgen replacement therapy.. Androgen. ... Biological function[edit]. Male prenatal development[edit]. Testes formation[edit]. During mammalian development, the gonads ... The Journal of Biological Chemistry. 280 (9): 7786-92. doi:10.1074/jbc.M413992200. PMID 15623502.. ...

https://en.wikipedia.org/wiki/Androgen

"11.100.20: Biological evaluation of medical devices". Retrieved 10 April 2009.. *^ International Organization for ... The precipitant for change was a radiation therapy device (Therac-25) that overdosed patients because of software coding errors ... ISO 10993 - Biological Evaluation of Medical Devices. Cleanliness standardsEdit. Medical device cleanliness has come under ... Therapeutic: physical therapy machines like continuous passive range of motion (CPM) machines ...

https://en.m.wikipedia.org/wiki/Medical_device

Lithium naturally only occurs in traces in biological systems and has no known biological role, but does have effects on the ... Sartori, H. E. (1984). "Cesium therapy in cancer patients". Pharmacol Biochem Behav. 21 (Suppl 1): 11-13. doi:10.1016/0091-3057 ... Biological role and precautionsEdit. MetalsEdit. Pure alkali metals are dangerously reactive with air and water and must be ... Rubidium has no known biological role, but may help stimulate metabolism,[234][235][236] and, similarly to caesium,[234][237] ...

https://en.m.wikipedia.org/wiki/Alkali_metal

Experimental treatments include targeted therapy, gamma knife radiosurgery,[45] boron neutron capture therapy and gene therapy. ... These differences probably reflect some biological differences as well as differences in pathologic diagnosis and reporting.[51 ... Radiation therapyEdit. The goal of radiation therapy is to kill tumor cells while leaving normal brain tissue unharmed. In ... "Molecular Therapy. 12 (5): 842-51. doi:10.1016/j.ymthe.2005.03.017. PMID 16257382. Archived from the original on 12 September ...

https://en.m.wikipedia.org/wiki/Brain_tumors

A. Al Dayela and N. al-Zuhair (2006), "Single drug therapy in the treatment of male sexual/erectile dysfunction in Islamic ... mirip dengan pakaian dipakai oleh askar-askar moden untuk perlindungan terhadap senjata biological, kimia dan nukelar. Oleh ...

https://ms.wikipedia.org/wiki/Reka_cipta_pada_zaman_pertengahan_Islam

American Cancer Society Complete Guide to Complementary and Alternative Cancer Therapies (2nd ed.). American Cancer Society. ... The Journal of Biological Chemistry. 279 (26): 27008-16. doi:10.1074/jbc.M403588200. PMID 15090535.. ... quercetin undergoes rapid and extensive metabolism that makes the biological effects presumed from in vitro studies unlikely to ... "The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems". (review). Food & ...

https://en.m.wikipedia.org/wiki/Quercetin

Katsambas AD, Dessinioti C (2010). "Hormonal therapy for acne: why not as first line therapy? facts and controversies". Clin. ... from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or ... See also: Management of prostate cancer § Hormonal therapy, and Androgen deprivation therapy ... Mario Maggi (30 January 2012). Hormonal Therapy for Male Sexual Dysfunction. John Wiley & Sons. pp. 6-. ISBN 978-0-470-65760-7. ...

https://en.m.wikipedia.org/wiki/Antiandrogen

Intravenous interferon therapy has also been used.[citation needed] When Lassa fever infects pregnant women late in their third ... Werner, Dietrich, editor (2004). Biological Resources and Migration. Springer. p. 363. ISBN 978-3-540-21470-0.. CS1 maint: ... Effective therapy with ribavirin". The New England Journal of Medicine. 314 (1): 20-26. doi:10.1056/NEJM198601023140104. ISSN ...

https://en.wikipedia.org/wiki/Lassa_fever

Biological warfare. *Carcinogen. *Food safety. *Hazard symbol. *List of extremely hazardous substances ...

https://en.wikipedia.org/wiki/Activated_charcoal

Research has identified health-behavioral and biological factors that are related to increased risk for CVD. These risk factors ... advantages of therapy with beta-receptor blockers. Clinical and Experimental Hypertension. Part A, Theory and Practice, 7(7), ...

https://en.wikipedia.org/wiki/Occupational_health_psychology

Aerosolized-augmented A1AT therapy is under study. This involves inhaling purified human A1AT into the lungs and trapping the ... Coakley RJ, Taggart C, O'Neill S, McElvaney NG (January 2001). "Alpha1-antitrypsin deficiency: biological answers to clinical ... Recombinant alpha-1 antitrypsin is not yet available for use as a drug but is under investigation as a therapy for alpha-1 ... These products for intravenous augmentation A1AT therapy can cost up to $100,000 per year per patient. They are administered ...

https://en.wikipedia.org/wiki/Alpha-1_antitrypsin

Biological Reviews. 78 (2): 251-345. doi:10.1017/S1464793102006103. PMID 12803423.. *^ a b Sahney, S., Benton, M.J. & Falcon- ... "Theraputic potential of snake venom in cancer therapy: current perspective". Asian Pacific Journal of Tropical Medicine. 3 (2 ... "Proceedings of the Royal Society B: Biological Sciences. 274 (1610): 635-640. doi:10.1098/rspb.2006.3763. PMC 2197205. PMID ... Biological and Biomedical Sciences. 39 (3): 298-313. doi:10.1016/j.shpsc.2008.06.004. PMID 18761282.. ...

https://en.m.wikipedia.org/wiki/Reptile

Targeted Radionuclide Tumor Therapy: Biological Aspects. Torgny Stigbrand,Jorgen Carlsson,Gregory P. Adams. No preview ... Targeted Radionuclide Tumor Therapy: Biological Aspects. Torgny Stigbrand,Jorgen Carlsson,Gregory P. Adams. No preview ... The title of this book "Targeted Radionuclide Tumour Therapy - Biological Aspects" was selected to reinforce the concept that a ... activation Affibody molecule affinity antigen apoptosis apoptotic Auger electrons binding biodistribution Biol biological ...

https://books.google.com/books?id=-mT0Lthq_54C

Biological therapies for cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Therapy/biological. ...

https://www.mayoclinic.org/tests-procedures/biological-therapy-for-cancer/care-at-mayo-clinic/clinical-trials/PRC-20022365

Biological reprogramming in acquired resistance to endocrine therapy of breast cancer. H Aguilar1, X Solé2,3, N Bonifaci2,3, J ... Ghayad et al., 2009). Notably, ERBB2 amplification was associated with resistance to endocrine therapies (. Ellis et al., 2006 ... Endocrine therapies are the most effective systemic treatment of estrogen receptor α (ERα)-positive breast cancer, and over two ... Winer et al., 2002). Two major strategies mediate the efficacy of these therapies. Drugs directed at ERα, mainly tamoxifen and ...

http://www.nature.com/onc/journal/v29/n45/full/onc2010333a.html?foxtrotcallback=true&error=cookies_not_supported&code=4e4de2b9-362c-43f6-b1eb-2244ff9569fc

Biological therapy may be used to treat chronic myelogenous leukemia in the chronic or accelerated phase. Learn about ... Biological therapy drug used for CML. Interferon alfa (Intron A, Wellferon) is the biological therapy occasionally used to ... Biological therapy is also called biotherapy or biological response modifiers (BRMs).. In most cases, targeted therapies are ... Biological therapy for chronic myelogenous leukemia. Biological therapy is sometimes used to treat chronic myelogenous leukemia ...

https://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/treatment/biological-therapy/?region=sk

... biological response modifiers and the family of cell adhesion-promoting molecules. ... Biological Treatments in Behçets Disease: Beyond Anti-TNF Therapy. Francesco Caso,1,2 Luisa Costa,3 Donato Rigante,4 Orso ... We found 44 cases of BD patients in therapy with biological agents other than anti-TNF-α agents. In particular, we found eight ... corticosteroid therapy is recommended for dural sinus thrombosis, while a combination therapy of corticosteroids with ...

https://www.hindawi.com/journals/mi/2014/107421/

Learn how and when biological therapy is used and side effects of biological therapy. ... Biological therapy is used treat certain types of non-Hodgkin lymphoma. ... Biological therapy is also called biotherapy or biological response modifiers (BRMs).. You may have biological therapy to:* ... Biological therapy for non-Hodgkin lymphoma. Biological therapy is sometimes used to treat non-Hodgkin lymphoma (NHL). It uses ...

http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/treatment/biological-therapy/?region=ab

Is it safe to use biologic therapies for psoriasis in women of child-bearing age? This systemic review found that the safety of ... Exposure to Biological Therapies During Conception and Pregnancy. A Systematic Review. E. Pottinger; R.T. Woolf; L.S. Exton; A. ... The aim of the review was to investigate outcomes in women exposed to biological therapies relevant to the treatment of ... has received departmental funding for research from pharmaceutical companies involved in manufacturing biological therapies ...

https://www.medscape.com/viewarticle/891748_2

Is it safe to use biologic therapies for psoriasis in women of child-bearing age? This systemic review found that the safety of ... Exposure to Biological Therapies During Conception and Pregnancy. A Systematic Review. E. Pottinger; R.T. Woolf; L.S. Exton; A. ... Background Biological therapies are effective treatments for psoriasis and are often prescribed to women of child-bearing age. ... All of the biological therapies currently licensed for psoriasis are derivatives of human immunoglobulin G (IgG) and are ...

https://www.medscape.com/viewarticle/891748_1

Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy.. Miller WR1, Dixon JM, Cameron DA, Anderson TJ. ... there was a decrease with therapy in immunohistochemical staining for Ki67 in all tumours. Staining for progesterone receptor ( ...

https://www.ncbi.nlm.nih.gov/pubmed/11850213?dopt=Abstract

Biological therapy downregulates the heterodimer S100A8/A9 (calprotectin) expression in psoriatic patients. ... the expression of the heterocomplex S100A8/A9 in lesional skin from psoriatic patients undergoing biological therapy with ... Balato A, Schiattarella M, Di Caprio R, Lembo S, Mattii M, Balato N, Ayala F. Effects of adalimumab therapy in adult subjects ... Furthermore, we have shown that the biological treatment induced a drastic reduction of S100A8/A9 expression in skin biopsies ...

https://link.springer.com/article/10.1007/s00011-018-1147-6

The light ions have a unique role in the development of modern radiation therapy where biological optimized radiation quality ... and intensity-modulated radiation therapy are increasingly coming into... ... The light ions have a unique role in the development of modern radiation therapy where biological optimized radiation quality ... Brahme A. (2011) Physical, Biological and Clinical Background for the Development of Light Ion Therapy. In: Levitt S., Purdy J ...

https://link.springer.com/chapter/10.1007/174_2011_265

Targeted (biological) therapies information for you Related. Order booklets or audio CDs about targeted (biological) therapies ... biological or hormonal therapies, transplants, and clinical trials.. Latest posts in Cancer treatments. Jenny62 replied to jane ...

https://www.macmillan.org.uk/information-and-support/breast-cancer/breast-cancer-in-men/treating/targeted-biological-therapies/find-your-therapy

CRISPR-Responsive Materials Deliver Therapy on Biological Cues. August 29th, 2019 Medgadget Editors Genetics, Materials, ... giving smart biological functionality to whatever material it is in. ... deliver therapies, and do things that are currently impossible. ... Nanoparticles for Large Gene Therapy to Cure Common Eye ...

https://www.medgadget.com/2019/08/crispr-responsive-materials-deliver-therapy-on-biological-cues.html?utm_source=dlvr.it&utm_medium=twitter

... By Jonathan Lotempio, Jr.. Scientific Program Analyst, NHGRI. Ludwig ... While gene therapy with AAV2/1-Cba-Tmc1 would likely not have helped Beethoven, since scholars can be nearly certain that he ... Gene therapy, however, may answer that technologic need. Adeno-associated viruses (AAV) have long been a promising vector for ... Tmc gene therapy restores auditory function in deaf mice. Sci Transl Med, 7(295):295ra108. 2015. [PubMed] ...

https://www.genome.gov/27562374/gene-therapy-and-the-biological-treatment-of-hearing-loss

Download all the latest market reports you need on the Biological Therapy Industry in Europe. Click here to instantly access ... Global Stem Cell Therapy Market Analysis & Trends - Ind ... $ 4200 November 2017 The Global Stem Cell Therapy Market is poised ... Biological Therapy Industry in Europe Market Research & Statistics. Biological Therapy Industry in Europe Market Research & ...

https://www.reportlinker.com/ci02233/Biological-Therapy.html/coverage/World:Europe

Download all the latest market reports you need on the Biological Therapy Industry in Thailand. Click here to instantly access ... Biological Therapy Industry in Thailand Market Research & Statistics. Biological Therapy Industry in Thailand Market Research ...

https://www.reportlinker.com/ci02233/Biological-Therapy.html/coverage/Asia:Thailand

Biological proteins have unlimited potential for use as pharmaceutical products due to their various biological activities, ... allow for the development of novel innovative protein-based products that draw on the quality of their innate biological ... review attempts to provide an overview of the development of protein-based products that take advantage of their biological ... Potential Use of Biological Proteins for Liver Failure Therapy. Kazuaki Taguchi 1. ...

https://www.mdpi.com/1999-4923/7/3/255

Expert Opinion on Biological Therapy is a monthly peer-reviewed medical journal covering research on all aspects of biological ... "Expert Opinion on Biological Therapy". 2017 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2018. ... therapy, including gene therapy and gene transfer technologies, therapeutic peptides and proteins, vaccines and antibodies, and ... cell- and tissue-based therapies. The journal is published by Taylor & Francis and the editor-in-chief is Michael Morse (Duke ...

https://en.wikipedia.org/wiki/Expert_Opinion_on_Biological_Therapy

Professor Working with Cincinnati Startup to Develop Biological Therapy. Cedarville News Professor Working with Cincinnati ... Startup to Develop Biological Therapy by Nathan Pilling, Public Relations Writer. Thursday, May 30, 2013. There is a growing ... to work on a novel biological approach to stabilize blood vessels. Photo credit: Scott L. Huck/Cedarville University ... to work on a novel biological approach to stabilize blood vessels. ...

https://www.cedarville.edu/News/2013/Professor-Working-with-Cincinnati-Startup-to-Develop-Biological-Therapy.aspx

Available until 30 September 2021. This one-day revision workshop is a revision back-up following on from the FRCR 1 statistics teaching session on 4 and 5 February.. ...

https://www.christie.nhs.uk/education/continuing-professional-development/study-days-and-conferences/biological-basis-of-cancer-therapy-part-b-video-recordings

... Steven M ... Other promising approaches include antiretroviral therapy with interleukin (IL) -2, and IFN-α wilh IL-2. The clinical research ... Therefore, approaches to attacking HIV via combination therapies have recently been under investigation. In particular, since ... pertaining to these combinations of antiretrovirals and biological response modifiers is reviewed. ...

https://www.hindawi.com/journals/cjidmm/1994/134340/abs/

Biological: aldesleukin Biological: cytokine therapy Biological: sargramostim Drug: carboplatin Drug: cyclophosphamide Drug: ... Biological Therapy in Treating Women With Metastatic Breast Cancer. The recruitment status of this study is unknown. The ... RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining ... PRIOR CONCURRENT THERAPY: See Disease Characteristics No concurrent hormonal therapy for breast cancer ...

https://clinicaltrials.gov/show/NCT00002780

TNF inhibiting biological therapies were initially used in IBD patients who werent responding to conventional therapy. They ... which often does not include traditional biological substances like vaccines. Today, biological therapy most commonly refers to ... Biological therapy has found a niche in the management of cancer, autoimmune diseases, and diseases of unknown cause that ... The advancements in biological therapy greatly changed how IBD is treated. Patients with Crohns disease and ulcerative colitis ...

https://en.wikipedia.org/wiki/Biological_therapy_for_inflammatory_bowel_disease

"Biological Therapy" by people in Harvard Catalyst Profiles by year, and whether "Biological Therapy" was a major or minor topic ... "Biological Therapy" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Biological Therapy" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Biological Therapy". ...

https://connects.catalyst.harvard.edu/Profiles/display/Concept/Biological%20Therapy

Thank you for your interest in either the Physical Therapy or Occupational Therapy Internship (Bio 498). Dr. Jim MacKenzie is ...

https://www.oswego.edu/biological-sciences/content/physical-and-occupational-therapy-internship-bio-498-questionnaire

People searching for Bachelors Degree in Biological Therapy found the following resources, articles, links, and information ... Bachelors Degree in Biological Therapy. Schools dont offer a biological therapy bachelors degree. For students who want to ... Diploma in Body Therapy: Program Overview Body therapy is generally used to describe massage therapy, body movement therapies, ... Students interested in biological therapy can earn a bachelors degree in immunology, biochemistry, or biology to learn the ...

https://study.com/articles/Bachelors_Degree_in_Biological_Therapy.html

Biological: aldesleukin Biological: lymphokine-activated killer cells Biological: therapeutic tumor infiltrating lymphocytes ... Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Combining biological ... Prostaglandin Inhibition Therapy plus Biological Response Modifier Therapy. Indomethacin; plus CTX; IL-2-activated TIL; IL-2. ... Indomethacin Plus Biological Therapy in Treating Patients With Advanced Melanoma. The safety and scientific validity of this ...

https://clinicaltrials.gov/ct2/show/NCT00002535

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Combined with acupuncture therapy, placental extract extends its therapeutic limit to pain control. Recently, we have reported ... Placenta Therapy: Its Biological Role of Anti-Inflammation and Regeneration. By Kyeong Mee Park, Dong Pill Cho and Tae Hwan Cho ... Kyeong Mee Park, Dong Pill Cho and Tae Hwan Cho (November 5th 2018). Placenta Therapy: Its Biological Role of Anti-Inflammation ... Kyeong Mee Park, Dong Pill Cho and Tae Hwan Cho (November 5th 2018). Placenta Therapy: Its Biological Role of Anti-Inflammation ...

https://www.intechopen.com/books/placenta/placenta-therapy-its-biological-role-of-anti-inflammation-and-regeneration

Cold viruses generally get a bad rap----which they've certainly earned----but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer. (biospace.com)

Targeted therapy, also called biologic therapy, uses the body's immune system or hormonal system to fight breast cancer cells. (webmd.com)
Although the use of antibodies to treat diseases can be dated back to the 1800s, biologic therapy as we know it today is a relatively new concept for the treatment of inflammatory bowel disease. (wikipedia.org)
Even so, biologic therapy still has its faults such as high cost and risk of side effects. (wikipedia.org)
Beaulieu DB, Ananthakrishnan AN, Martin C, Cohen RD, Kane SV, Mahadevan U. Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines. (harvard.edu)
Variations in Health Insurance Policies Regarding Biologic Therapy Use in Inflammatory Bowel Disease. (harvard.edu)
Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases. (harvard.edu)
Switching profiles in a population-based cohort of rheumatoid arthritis receiving biologic therapy: results from the KOBIO registry. (harvard.edu)
Side effects of biologic therapy were infections such as urinary tract infections and soft tissue abscess. (dovepress.com)
All these factors can inhibit the growth of global cancer biologic therapy market trend. (fractovia.org)
Japan cancer biologic therapy market share contributed for more than 40.1% of overall revenue share of APAC for 2015 owing to its rising old age population. (fractovia.org)
this will be compared with physical activity levels at baseline and the change in these level pre and post treatment with biologic therapy. (bioportfolio.com)

Biological therapy is also called biotherapy or biological response modifiers (BRMs). (cancer.ca)
The clinical research pertaining to these combinations of antiretrovirals and biological response modifiers is reviewed. (hindawi.com)
Biological response modifiers - change the way the body's defenses interact with cancer cells. (vcu.edu)

Two major strategies mediate the efficacy of these therapies. (nature.com)
The aim of our study was to evaluate the efficacy and safety of biological therapy for AOSD resistant to traditional therapy. (dovepress.com)
The efficacy of biological therapy and overall tolerance of biological therapy for refractory AOSD were good. (dovepress.com)
Discussion ETN has proved its efficacy in JIA (regardless of the type of onset), as it has been reported in multiple efficacy and safety studies, including long term studies of up to eight years of continuous therapy. (bmj.com)
While replacement therapy remained unrealistic, the clinical efficacy of this therapeutic option could be potentially enhanced if we could better decipher the mechanisms underlying some of the beneficial effects of transplanted cells, and work toward augmenting or combining these in a strategic manner. (degruyter.com)

Many types of biological therapy are available only in clinical trials. (mayoclinic.org)
Different types of biological therapies work in different ways. (cancer.ca)
Combining different types of biological therapies may kill more tumor cells. (clinicaltrials.gov)
What are the different types of biological therapies? (vcu.edu)
Many types of biological therapy are available only in clinical trails Biological therapy for cancer treatment is a very active area of cancer treatment. (findatopdoc.com)

https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/bio-therapies-fact-sheet. (mayoclinic.org)
Biological therapy, otherwise known as immunotherapy, is an innovative procedure used to treat cancer through immune system techniques. (study.com)
Biological therapy (also called immunotherapy, biological response modifier therapy or biotherapy) uses the body's immune system to fight cancer. (vcu.edu)
Biological therapy is also called immunotherapy, biological response modifier therapy, or biotherapy. (vidanthealth.com)
Radio-immunotherapy therapy, photodynamic therapy, and thermal therapies can also be classified under this heading. (survivingmesothelioma.com)

Biological therapy for cancer often causes fewer toxic side effects than do other cancer treatments. (mayoclinic.org)
There are several ways biological therapy treatments can achieve this goal. (mayoclinic.org)
Background Biological therapies are effective treatments for psoriasis and are often prescribed to women of child-bearing age. (medscape.com)
Biological therapies are effective treatments for psoriasis that specifically block proinflammatory cytokine pathways central to disease immunopathogenesis. (medscape.com)
They can also be combined with other treatments, such as chemotherapy and radiation therapy. (vidanthealth.com)
Hormone therapy is used to treat breast cancer that is hormone sensitive ( where the presence of estrogen and/or progesterone receptors are found) These hormone treatments work by lowering the level of estrogen in the body or by blocking the action of estrogen on breast cancer cells. (nygh.on.ca)
Main outcome measures included change in the ongoing treatments with corticosteroids, IMT and biological agents, use of alternate therapies and rates of uveitis relapse. (bmj.com)

Data generated from both clinical trials and model systems indicate that both types of therapy may prevent the progression of pump dysfunction that characterizes the natural history of heart failure and, unexpectedly and remarkably, that β-blockade may substantially improve pump function in the long term. (ahajournals.org)
The report covers biological products in development, biological products in clinical trials, and currently marketed and late-stage development biologic cancer products. (bccresearch.com)
Noncytotoxic maneuvers that short circuit damage resistance loops may thus represent an indirect form of gene therapy meriting incorporation into hepatocellular carcinoma clinical trials. (aacrjournals.org)
Allowing Innovative Stem Cell-Based Therapies Outside of Clinical Trials: Ethical and Policy Challenges. (philpapers.org)

Biological therapy for cancer is a type of treatment that uses the body's immune system to kill cancer cells. (mayoclinic.org)
The goal of biological therapy for cancer is to induce your immune system to recognize and kill cancer cells. (mayoclinic.org)
Biological therapy can also target the cancer cells, turning on or off cell signals that help them elude the immune system cells. (mayoclinic.org)
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. (clinicaltrials.gov)
Today, biological therapy most commonly refers to the use of proteins, such as monoclonal antibodies, to regulate the immune system in the treatment of disease. (wikipedia.org)
Prior to the development of biological therapy as a modality to treat IBD, other medications that modulate the immune system-including 5-aminosalicylates, steroids, azathioprine, and other immunosuppressants-were primarily used in treatment. (wikipedia.org)
Nonspecific immunomodulating agents - biological therapy drugs that stimulate the immune system, causing it to produce more cytokines and antibodies to help fight cancer and infections in the body. (vcu.edu)
Biological therapies are designed to boost the immune system, either directly or indirectly. (vidanthealth.com)
Nonspecific immunomodulating agents are biological therapy drugs that stimulate the immune system in a general way. (vidanthealth.com)
Biological therapy targets work with your immune system to target cancer cells, unlike traditional chemotherapy, which kills dividing cells (whether normal or cancerous). (nygh.on.ca)
RATIONALE: Biological therapies, such as agatolimod, may stimulate the immune system in different ways and stop tumor cells from growing. (bioportfolio.com)
Nevertheless, the immune system can recognize the administered biological as non-self and respond with generation of anti-drug antibodies (ADA), including neutralizing ADA (nADA). (fraunhofer.de)
In general, biological therapies work in one of two ways: Inducing the immune system to attack cells. (findatopdoc.com)

The aim of the review was to investigate outcomes in women exposed to biological therapies relevant to the treatment of psoriasis at conception and/or during pregnancy to assess the impact of such exposure. (medscape.com)
Population-based cohort studies or clinical trial data were eligible for review which evaluated pregnancy outcomes in women exposed during conception or pregnancy to biological therapies relevant to the treatment of psoriasis. (medscape.com)
Psoriasis often first develops in young adults, of which a significant number may require treatment with a biological agent. (medscape.com)
All of the biological therapies currently licensed for psoriasis are derivatives of human immunoglobulin G (IgG) and are actively transported across the placenta via neonatal Fc receptors. (medscape.com)

Therefore, additional therapies for a subset of refractory patients with BD are inevitably needed. (hindawi.com)
The advent of biological tumor necrosis factor-α (TNF-α) inhibitors has led to substantial improvement in management of severe and active PsA refractory to conventional DMARD. (jrheum.org)
CD19-specific chimeric antigen receptor (CAR) T-cell therapy is highly effective against relapsed or refractory acute lymphoblastic leukemia (ALL), but is hindered by neurotoxicity. (aacrjournals.org)
The investigation of molecular biological mechanisms and therapy of refractory renal edema. (nii.ac.jp)
This study was designed to investigate the mechanisms and therapy of refractory renal edema. (nii.ac.jp)

One type of targeted therapy uses antibodies to kill cancer cells or block them from growing. (webmd.com)
Another type of this therapy uses drugs made of small molecules that block signals the cancer cells need to grow. (webmd.com)
The type of targeted therapy your doctor might recommend depends on the type of breast cancer you have. (webmd.com)
Some postmenopausal women with certain types of advanced breast cancer may get a prescription for palbociclib (Ibrance) or ribociclib (Kisqali) along with hormone therapy. (webmd.com)
Biological therapy for cancer is used in the treatment of many types of cancer to prevent or slow tumor growth and to prevent the spread of cancer. (mayoclinic.org)
Biological therapy for cancer is a very active area of cancer research. (mayoclinic.org)
2 studies in Biological therapy for cancer (open studies only). (mayoclinic.org)
http://www.cancer.gov/cancertopics/factsheet/Therapy/biological. (mayoclinic.org)
Endocrine therapies targeting the proliferative effect of 17β-estradiol through estrogen receptor α (ER α ) are the most effective systemic treatment of ER α -positive breast cancer. (nature.com)
This study provides mechanistic insight into acquired resistance to endocrine therapies of breast cancer and highlights a potential therapeutic strategy. (nature.com)
Biological therapy has found a niche in the management of cancer, autoimmune diseases, and diseases of unknown cause that result in symptoms due to immune related mechanisms. (wikipedia.org)
Systemic Therapies for Nonmetastatic Breast Cancer: The Role of Neoadjuvant and Adjuvant Chemotherapy and the Use of Endocrine Therapy. (harvard.edu)
They also are produced in the laboratory and given to cancer patients in biological therapy. (vcu.edu)
Biological therapies can be used alone to treat cancer. (vidanthealth.com)
PlacidWay Medical Tourism provides cost comparison for Biological Hormone Therapy, Cancer Treatment Prices in Gurgaon, India. (placidway.com)
Stem Cell Therapy for Cancer (Brain Tumor) is quite a popular orthopedic procedure in Beijing, China. (placidway.com)
Increase in proportion of different kinds of cancers and rising acceptance of biological treatment is predicted to drive global cancer biological therapy industry trends. (fractovia.org)
Increase in aging population all across the globe is projected to fuel global biological cancer therapy industry due to correlation between aging and new cases. (fractovia.org)
High treatment cost of cancer therapy is mainly owing to high price of medicines. (fractovia.org)
Global cancer biological therapy industry was segmented into products like cytokines, monoclonal antibodies, blood cell growth factors, monoclonal antibodies and vaccines. (fractovia.org)
Global cancer biological therapy market is segmented into geographical locations like APAC, North America, MEA, Europe and LATAM. (fractovia.org)
Germany cancer biological therapy market contributed more than $4.4 billion for 2015 and is predicted to maintain its revenue share domination owing to rising occurrence and favorable compensation & insurance policies. (fractovia.org)
This report provides an update on BIO048B Biological Therapies for Cancer: Technologies and Global Markets. (bccresearch.com)
The global market for biological therapies for cancer was worth $37.9 billion in 2009, down from $38 billion in 2008. (bccresearch.com)
Biological therapy takes place in the Baruch/Weisz Cancer Centre at the General site. (nygh.on.ca)
Complementary or alternative therapy includes all therapy, or products that are not part of conventional cancer care. (nygh.on.ca)
Will there be any interactions between the complementary therapy and your conventional cancer treatment? (nygh.on.ca)
The findings, published October 11 in Cell, suggest a new avenue for developing cancer therapies by mimicking the strategies employed by the viruses. (biospace.com)
These findings suggest that reovirus therapy may provide a promising novel treatment for prostate cancer and also imply a possible role for viral immune targeting of tumor. (aacrjournals.org)
These interactions are being investigated for applications in cancer therapy. (jove.com)
Andre Goy, MD, MS, chief, Division of Lymphoma, chairman and director, John Theurer Cancer Center, discusses the combination of biological therapies in the treatment of patients with relapsed mantle cell lymphoma (MCL). (onclive.com)
Na[COSAN], which displays low toxicity and high uptake by relevant cancer cells accumulating boron within the nucleus, could act as a suitable compound for further developments as boron neutron capture therapy (BNCT) agents. (icmab.es)
Proton therapy is undergoing a rapid development making it increasingly popular as a treatment of cancer. (uib.no)
The Hyperthermia Centre in Hannover is among the leading biological cancer treatment clinics in Germany. (hyperthermia-centre-hannover.com)
Michael G. Harris Cell Therapy and Cell Engineering Facility, Memorial Sloan Kettering Cancer Center, New York, New York. (aacrjournals.org)
1 What is a Biological Therapy for Cancer? (findatopdoc.com)
Have a question about Biological Therapy For Cancer? (findatopdoc.com)
Read on to learn more what to expect about your biological therapy for cancer . (findatopdoc.com)
The results of a biological therapy for cancer will be given by your doctor. (findatopdoc.com)

However, most breast tumors initially responsive to these therapies develop resistance through molecular mechanisms that are not yet fully understood. (nature.com)
However, although endocrine therapies are initially effective, resistance occurs both in the form of tumor relapse after excision during adjuvant treatment and as a near-universal event when tumors cannot be excised. (nature.com)
DEDIĆ PLAVETIĆ NDP, BARIĆ MB, BRADIĆ LB, KULIĆ A, PLEŠTINA S. Hypoxia in solid tumors: biological responses to hypoxia and implications on therapy and prognosis. (srce.hr)
N.D.P. DEDIĆ PLAVETIĆ, M.B. BARIĆ, L.B. BRADIĆ, A. KULIĆ i S. PLEŠTINA, "Hypoxia in solid tumors: biological responses to hypoxia and implications on therapy and prognosis", Periodicum biologorum , vol.116, br. (srce.hr)
Methods to augment the biological action of radiation therapy in prostate and other tumors without additional toxicity to surrounding normal tissues would be useful for improving the therapeutic ratio. (nanotech-now.com)
This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. (ebookee.org)

In most cases, targeted therapies are now the main treatment for CML. (cancer.ca)
However, although biological treatment with anti-TNF- α agents has been largely demonstrated to be effective in BD, not all patients are definite responders, and this beneficial response might drop off over time. (hindawi.com)
Furthermore, we have shown that the biological treatment induced a drastic reduction of S100A8/A9 expression in skin biopsies from treated patients, correlating with PASI reduction. (springer.com)
Brahme A (2009) Potential developments of light ion therapy: the ultimate conformal treatment modality. (springer.com)
Order booklets or audio CDs about targeted (biological) therapies, how they work, having treatment and how it might affect you. (macmillan.org.uk)
This review attempts to provide an overview of the development of protein-based products that take advantage of their biological activity for medication, and discusses possibilities for the therapeutic potential of protein-based products produced through different approaches to specifically target the liver (or hepatic cells: hepatocytes, hepatic stellate cells, liver sinusoidal endothelial cells, and Kupffer cells) in the treatment of hepatic diseases. (mdpi.com)
Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. (wikipedia.org)
Given this, a variety of biological therapies (such as TNF inhibitors and interleukin antagonists) have been developed for the treatment of these diseases. (wikipedia.org)
The previous treatment options had many shortcomings, and the introduction of biological therapy changed the way physicians treat Crohn's disease and ulcerative colitis. (wikipedia.org)
16 17 18 19 20 These two types of therapies, ACE inhibitors and β-adrenergic-blocking agents, have changed our thinking about the potential of medical treatment of heart failure. (ahajournals.org)
Chapters present treatment strategies for those conditions for which research and clinical experience have clearly demonstrated the benefits of combination therapy-major depression, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, sleep disorders, schizophrenia, bipolar disorder, borderline personality, and generalized anxiety disorder. (silverplatter.com)
Advances in imaging and biological targeting have led to the development of stereotactic body radiation therapy (SBRT) as an alternative treatment of extracranial oligometastases. (biomedsearch.com)
Boron neutron capture therapy (BNCT) has been investigated as a potential treatment for glioblastoma multiforme (GBM), head and neck cancers, melanoma, and other tumor sites for many decades. (mdpi.com)
Biological therapies for treatment of other diseases will not be addressed in this report. (bccresearch.com)
Are there any special instructions I should follow before, during, and after each biological treatment? (nygh.on.ca)
At diagnosis, mean age was 4.94 ± 2.9, and at the beginning of biological treatment of 8.77 ± 2.63. (bmj.com)
Actually all the children are in remission, two of them (patients 1 and 4) without biological treatment or classic DMARDs (since 5 and 2 years respectively). (bmj.com)
Biological therapy means treatment with agents that are natural biologic products (such as antibodies from other species, etc. (healthtap.com)
To analyze the details of treatment, treatment outcomes and associated-systemic diseases in the scleritis patients who have received immunosuppressant and biological agents at Ocular Inflammation Service of the Nippon Medical School Hospital (NMSH), Ophthalmology. (arvojournals.org)
ALL of 24 patients succeeded in steroid-sparing after treatment with immunosuppressant or biological agents, and 10 out of 24 patients were eventually led to steroid-free. (arvojournals.org)
Immunosupressant and biological agents are effective treatment for scleritis. (arvojournals.org)
The subjects who are eligible to enter in the study will receive his/her normal treatment prescribed and be at the referral phase for biological treatment. (bioportfolio.com)
A disease activity score (aggregate score of RA symptoms - DAS) for the RA population will be calculated by a nurse specialist at the time of referral for the biological agent and again at 12 weeks post treatment, these parameters will not be repeated by the research team but the DAS score will be collected used in the final analysis. (bioportfolio.com)
This screening / baseline visit will occur before, but as near as possible to the 1st treatment day of the prescribed biological agent. (bioportfolio.com)
Some patients with these cancers can be treated with targeted genetic therapies, and some benefit from immunotherapies-but the vast majority of NSCLC patients have no treatment options except for chemotherapy. (salk.edu)
Future research may further identify when and/or which patients are most likely to discontinue biological treatment successfully. (nih.gov)
To evaluate the performance of biological drugs in psoriatic arthritis (PsA) in a routine care setting, using the Finnish national register of biological treatment (ROB-FIN). (jrheum.org)
However, evidence of the clinical benefit of DMARD therapy in treatment of PsA is largely inconclusive 3 , 4 . (jrheum.org)
To evaluate the effectiveness and adverse events (AE) of biological therapies in the treatment of inflammatory arthritides, the Finnish Society for Rheumatology has set up a national register of biological treatment (ROB-FIN) 9 , 10 , 11 , 12 , 13 , maintained with approval from the Internal Medicine Ethics Committee of the Hospital District of Helsinki and Uusimaa. (jrheum.org)
Patient selection for biological therapy of PsA with peripheral arthritis has, presumably, been based on the national evidence-based treatment recommendations (the so-called Current Care guidelines) for rheumatoid arthritis (RA) 18 , but with modification based on the clinical judgment of a specialist to accomodate individual patient needs. (jrheum.org)
Introduction: Proton therapy is a radiation treatment method growing around the world. (uib.no)
To account for this increased relative biological effectiveness (RBE), a constant RBE of 1.1 is applied in clinical proton therapy treatment planning, i.e. approximately 10% lower physical dose is given to the tumor if proton therapy is used. (uib.no)
The aim of this study was to implement a method for optimization of treatment plans with respect to both biological and physical dose, and further use this to analyze the differences in physical and biological dose distributions depending on the optimization strategies applied. (uib.no)
The aim of this prospective, randomized, clinical trial was to compare outcomes of treatment in persons with chronic diabetic foot ulcers (DFUs) randomly assigned to transdermal continuous oxygen therapy (TCOT) for 4 weeks as an adjunct to standard care (debridement, offloading, and moisture). (o-wm.com)
High-energy Extracorporeal Shock-Wave Therapy (ESWT) for the treatment of chronic plantar fasciitis. (semanticscholar.org)

In this paper, we present a computational, multiscale system of models to better assess the relative biological effectiveness (RBE) and compound biological effectiveness (CBE) of several neutron sources as applied to BNCT using boronophenylalanine (BPA) and a potential monoclonal antibody (mAb) that targets HER-2-positive cells with Trastuzumab. (mdpi.com)
However, even though there is extensive experience in the clinical use of protons, there remains much to be learned regarding the relative biological effectiveness (RBE) of protons in relation to photons. (bl.uk)
This difference in biological response is quantified by the relative biological effectiveness (RBE), which aid the comparison of the dose deposition from the two modalities and enables transferal of established clinical protocols from photon therapy to proton therapy. (uib.no)

July's Genome Advance of the Month highlights a study in the journal Science Translational Medicine that demonstrated gene therapy as an effective way to improve hearing in patients with two genes linked to genetic prelingual deafness, or hearing loss that occurs before a child learns to speak. (genome.gov)
The study's authors, Charles Askew, Ph.D., Jeffery R. Holt, Ph.D. and colleagues at École Polytechnique Fédérale de Lausanne in Switzerland, examined the use of gene therapy to cure hereditary deafness in mice with two types of Tmc1 mutations. (genome.gov)
Gene therapy, however, may answer that technologic need. (genome.gov)
Adeno-associated viruses (AAV) have long been a promising vector for human gene therapy due to their apparent inability to cause disease or integrate their viral genome into the human host genome. (genome.gov)
The hearing abilities of mice treated with this gene therapy were tested by analyzing the brain function and startle response to unexpected auditory stimuli (sounds). (genome.gov)
While gene therapy with AAV2/1- Cba - Tmc1 would likely not have helped Beethoven, since scholars can be nearly certain that he was not a carrier of a mutant TMC1 gene, this promising genomic discovery may eventually enable those who do have deafness caused by a TMC1 mutation to regain their ability to hear. (genome.gov)
Expert Opinion on Biological Therapy is a monthly peer-reviewed medical journal covering research on all aspects of biological therapy, including gene therapy and gene transfer technologies, therapeutic peptides and proteins, vaccines and antibodies, and cell- and tissue-based therapies. (wikipedia.org)
What are 3 benefits of gene therapy? (healthtap.com)
Here is some comprehensive information about gene therapy . (healthtap.com)
This suggests that STAT3 is a promising molecular target for HCC gene therapy. (checkorphan.org)

The aim of this review is to summarize all current experiences and the most recent evidence regarding these novel approaches with biological drugs other than TNF- α blockers in BD, providing a valuable addition to the actually available therapeutic armamentarium. (hindawi.com)
Combined with acupuncture therapy, placental extract extends its therapeutic limit to pain control. (intechopen.com)
The journal provides assistance in the development of knowledge about biological markers, fast operative publication of scientific advances to the development of new guided-therapeutic strategies based on diagnostic, and prognostic biological markers to help scientists cooperation in their different modern researches. (m-hikari.com)
These implantable devices are an essential technical component of radiation delivery during Image Guided Radiation Therapy (IGRT), but are inert and provide no direct therapeutic function. (nanotech-now.com)
In this review, we therefore discuss biological and potential therapeutic effects of ortho-silicic acid and ortho-silicic acid -releasing silicon compounds as its major natural sources. (nih.gov)

Explore Biological Hormone Therapy prices worldwide. (placidway.com)
Plant derivatives and hormone therapy corticosteroids. (bccresearch.com)
Hormone therapy is a pill that is taken daily. (nygh.on.ca)
Side effects may arise from hormone therapy. (nygh.on.ca)
What are the benefits and risks of hormone therapy? (nygh.on.ca)
What type of hormone therapy am I getting? (nygh.on.ca)
You will need to have blood drawn in the outpatient lab on the 4th floor , the day before you begin hormone therapy. (nygh.on.ca)

Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy. (nih.gov)
Thirty two of 271 patients given anti-TNF-α therapies (11.81%), 116 patients receiving IL-1 inhibitors (65.54%), 124 patients receiving tocilizumab (76.07%), and 13 patients given other biological therapies (36.11%) achieved remission. (dovepress.com)
Biological therapies can be defined as targeted therapies used to attack a particular protein, enzyme or other cellular component or an approach using inhibitors (i.e. anti-angiogenesis), monoclonal antibodies or other substances. (survivingmesothelioma.com)

After achieving low disease activity or remission, biological therapy might be stopped in rheumatoid arthritis patients, but information on whether and how this should be done is scarce. (nih.gov)
In most studies, patients were required to have low disease activity or be in clinical remission for at least 6 months before biological therapy was discontinued. (nih.gov)
In conclusion, in the absence of a guideline for stopping biologicals in RA, we present a preliminary proposal that biological therapy can be stopped in many RA-patients after achieving low disease activity or remission for at least 6 months. (nih.gov)

Background Biological therapies have dramatically changed the prognosis for children with juvenile idiopathic arthritis (JIA). (bmj.com)
Background- Biological pacing performed solely via HCN2 gene transfer in vivo results in relatively slow idioventricular rates and only moderate autonomic responsiveness. (ahajournals.org)

Although clinical data shows much beneficial effects of biological therapies in terms of reduction of exacerbation rates, improvement of lung functions, asthma control and patients' quality of life, little is known on the effects of these monoclonal antibodies on AR-a key clinical trait of long-term asthma management. (frontiersin.org)

Please contact the chemotherapy clinic if you have any questions or concerns regarding biological therapy. (nygh.on.ca)

Your healthcare team will consider your personal needs to plan the drugs, doses and schedules of biological therapy. (cancer.ca)
Photodynamic Therapy a technique that uses non-thermal lasers to activate light-sensitive drugs. (survivingmesothelioma.com)
Biologic drugs, which are synthesised within a biological system, have been designed to target specific molecules involved in cytokine signalling or cell-cell interactions. (bmj.com)
Anti-tumor necrosis factor-α therapy, often combined with conventional disease-modifying antirheumatic drugs, appeared to have limited toxicity and persistent effectiveness for up to 2 years in a cohort of Finnish patients with severe peripheral PsA. (jrheum.org)
Conventional drug therapy of PsA has mainly consisted of nonsteroidal antiinflammatory drugs (NSAID), intraarticular steroids, and disease modifying antirheumatic drugs (DMARD), of which methotrexate (MTX), sulfasalazine (SSZ), cyclosporine (CSA), and leflunomide (LEF) alone or in combination are the most widely used. (jrheum.org)
Therefore, STAT3 may become an important target of biological therapy in HCC, which brings hope of clinical therapy using RNAi oligonucleotide drugs. (checkorphan.org)
The aim of this study was to assess disease status and quality of life in an outpatient population treated with biological disease-modifying anti-rheumatic drugs. (lancs.ac.uk)
Material and Methods: Cross-sectional study recalling all patients ever treated in our unit with biological disease-modifying anti-rheumatic drugs. (lancs.ac.uk)

Drug Therapy is the control of psychological disorders through medications. (slideserve.com)

This is mainly due to the protons ability to deposit dose more conformal compared to conventional photon therapy. (uib.no)
Protons interact differently with the tissue compared to conventional radiation therapy with photons, resulting in a more beneficial dose distribution with greater dose conformation. (uib.no)

Even for diseases of unknown cause, molecules that are involved in the disease process have been identified, and can be targeted for biological therapy. (wikipedia.org)
Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease. (degruyter.com)
Download this slideset for an expert-curated overview of emerging biological therapies for β-thalassemia, including review of the latest clinical data leading to the recent approval of the erythroid maturation agent luspatercept for transfusion-dependent disease. (clinicaloptions.com)
and (2) if a baseline report, i.e., patient demographic data and disease profile at commencement of biological therapy, had been filed. (jrheum.org)
Biological therapy was started at a median of four years following disease onset. (lancs.ac.uk)
Conclusion: Despite therapy switches and regular follow-up, a significant percentage of patients still presented with moderate disease activity, functional impairment and a poor health-related quality of life. (lancs.ac.uk)

tips descended edited to merit the natural book Molecular Markers of Brain Tumor Cells: Implications for Diagnosis, Prognosis and Anti Neoplastic Biological Therapy, or the dyslexia, ability, and TA. (nuttyb.com)
Robert Estienne( 1503-1559) laid Henri particular right book Molecular Markers of Brain Tumor Cells: Implications for Diagnosis, Prognosis and Anti Neoplastic Biological Therapy. (nuttyb.com)
Noli book Molecular Markers of Brain Tumor Cells: Implications for Diagnosis, Prognosis and Anti Neoplastic Biological %, normally with the n jump learning. (nuttyb.com)
Fire Out Creators,( Youth Football Online), involves infected to Using any and all necessary book Molecular Markers of Brain Tumor Cells: Implications for Diagnosis, Prognosis and Anti Neoplastic Biological Therapy left of those scenes that reverence our 9 and spread expansion of our printed organizations and personnel online, slow, local and likely. (nuttyb.com)

The remaining challenge to a more wide spread clinical use of light ions are to improve the sensitivity and specificity of Molecular Tumor Imaging to more accurately localize the tumor tissues and their biological characteristics as well as to develop fast scanning systems that preserve the fundamental biological and physical advantages of the light ions. (springer.com)
Her primary focus areas include oncology and cardiovascular diseases, along with expertise in molecular and cell biology and complex cell-based biological assays, ranging from drug discovery, in vitro and in vivo screening, in vivo model development and pharmacokinetics. (bccresearch.com)
Special emphasis is given to already established and emerging molecular diagnostic tests in neuropathology, as well as molecular targeted therapies. (ebookee.org)

Side effects of biological therapy will depend mainly on the type of drug, the dose and your overall health. (cancer.ca)
The traditional dose distributional qualities of light ions like penumbra and depth dose are ideally suited for high-quality radiation therapy, and their radiation biological properties are even more important for eradicating large complex generally radiation resistant and/or hypoxic tumor volumes with minimal damage to surrounding normal tissues. (springer.com)
Brahme A (2011) Accurate description of the cell survival and biological effect at low and high dose and LET's. (springer.com)
Experimental RBE values were in excellent agreement with local effect model predicted values, indicating that dose-averaged LET is a suitable predictor of proton biological effectiveness. (bl.uk)
Protons also differ in terms of biological effect compared to photons for the same physical dose. (uib.no)
By using biological optimization the tumor may get a homogenous biological dose distribution, and prevent over- and under dosage to healthy tissue and the tumor volume. (uib.no)
These data suggest that the antiangiogenic activity of IFN-α is dependent on frequent administration of optimal biological dose and not maximal tolerated dose. (aacrjournals.org)
We show that maximal inhibition of angiogenesis-regulating genes and tumorigenicity depends on the optimal biological dose (not maximal tolerated dose) and frequency of administration. (aacrjournals.org)
Methods for early detection of kidney damage that-in this case-cannot be predicted based on dose estimations, would facilitate the development of novel therapies. (uzh.ch)

Aguilar-Company J, Fernández-Ruiz M, García-Campelo R, Garrido-Castro AC, Ruiz-Camps I. ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Cell surface receptors and associated signaling pathways). (harvard.edu)

A conservative and constant RBE of 1.1 is used in proton therapy clinics, even though experiments have shown that the RBE can be both higher and lower, varying with different biological and physical quantities, including the LET value. (uib.no)

The light ions have a unique role in the development of modern radiation therapy where biological optimized radiation quality and intensity-modulated radiation therapy are increasingly coming into clinical interest, not least through a systems biology approach to therapy optimization. (springer.com)
Brahme A (1984) Dosimetric precision requirements in radiation therapy. (springer.com)
Brahme A (1988) Optimization of stationary and moving beam radiation therapy techniques. (springer.com)
Brahme A (2003) Biologically optimized 3-dimensional in vivo predictive assay based radiation therapy using positron emission tomography-computerized tomography imaging. (springer.com)
Brahme A (2004) Recent advances in light ion radiation therapy. (springer.com)
Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review. (biomedsearch.com)
Radiation therapy. (bccresearch.com)
In order to achieve high spatial accuracy, modern radiation therapy practice routinely utilizes implantation of fiducials (external beam therapy) or radioactive source spacers (brachytherapy) into the tumor. (nanotech-now.com)

Major improvements in the natural history of advanced hepatocellular carcinoma thus seem dependent on a quantum leap in medical therapy. (aacrjournals.org)
First, the drug resistance of hepatocellular carcinoma means that no standard therapy exists against which to compare innovative regimens. (aacrjournals.org)

The aim of this study was to investigate the microRNA expression pattern in neutrophils from rheumatoid arthritis patients and its contribution to their pathogenic profile and to analyze the effect of specific autoantibodies or inflammatory components in the regulation of microRNAs in rheumatoid arthritis neutrophils and its modulation by biological therapies. (haematologica.org)

Accurate dosimetry and determination of the biological effectiveness of boron neutron capture therapy (BNCT) is challenging because of the mix of different types and energies of radiation at the cellular and subcellular levels. (mdpi.com)

It allows experimental data to be uploaded to the cloud where it can be analyzed at scale using advanced machine learning and data analysis methods, to generate biological knowledge. (princeton.edu)
Matherials and Methods We identified 9 children with JIA treated with biologic therapies, and we made a description of our experience. (bmj.com)
Methods In this national multicentric prospective case series, data of subjects with NIU receiving corticosteroids, systemic IMT and/or biological agents were analysed. (bmj.com)

The areas covered include basic and clinical research, including studies in cardiovascular medicine, endocrinology, neurological diseases, oncology, wherever guided-therapy with biological markers is used. (m-hikari.com)

The invention concerns a flexible catheter of preferably biocompatible plastic material comprising at least one electrode disposed at the distal end of the catheter for high-frequency therapy of biological tissue. (google.com)
During a high-frequency therapy procedure, the application of a high-frequency ac voltage between two electrodes causes an electric current to be produced in the body tissue between the electrodes, and the result of that electric current is an increase in temperature of the body tissue surrounding the electrodes. (google.com)
The biological effects of extracorporeal shock wave therapy (eswt) on tendon tissue. (semanticscholar.org)

Other promising approaches include antiretroviral therapy with interleukin (IL) -2, and IFN-α wilh IL-2. (hindawi.com)

Purpose To evaluate the change in the ongoing immunomodulatory (IMT) and biological therapies among patients with non-infectious uveitis (NIU), and determine the number of uveitis relapses during the COVID-19 pandemic. (bmj.com)

Objectives To evaluate the safety of biological therapy in conception and/or pregnancy. (medscape.com)

However, when these biological therapies are combined, specifically rituximab (Rituxan) and lenalidomide (Revlimid) or venetoclax (Venclexta) and ibrutinib (Imbruvica), CR rates become more evident. (onclive.com)

Biological therapy uses natural or artificial substances that change the way cells behave. (cancer.ca)
The development of recombinant DNA technology in the 1970s shaped the modern understanding of what constitutes as biological therapy, which often does not include traditional biological substances like vaccines. (wikipedia.org)

Irradiation experiments on cells and animal models have shown that protons are slightly more effective in producing biological damage than photons. (uib.no)

The aim of this study was to investigate, by immunohistochemical analysis, the expression of the heterocomplex S100A8/A9 in lesional skin from psoriatic patients undergoing biological therapy with adalimumab, etanercept or ustekinumab. (springer.com)

The research team led by Professor Piao from Liaoning Medical University and Jinlin University applied a DNA vector-based STAT3-specific RNA interfering approach to block STAT3 signaling and to evaluate the biological consequences of STAT3 down-modulation on tumor growth using a tumor-bearing nude mice model. (checkorphan.org)
While biological drug therapies have become popular in the last few years, it is important to evaluate the safety of these medications. (daavlin.com)

This work combines programming languages and compilers, which generate biological protocols that can be executed using lab automation technology. (princeton.edu)
Focussing on the key biological endpoints of cell survival and DNA damage, this work presents a comparative investigation of the biological effectiveness of clinical proton beams using normal and radioresistant human cells. (bl.uk)

Anatomy1

Diseases13

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Psychiatry and Psychology1

Phenomena and Processes3

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena3

Information Science1

Health Care4

Geographicals1

New treatment strategies for malignant gliomas. (1/231)

Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. (2/231)

Where is biological therapy going? (3/231)

Probiotic agents and infectious diseases: a modern perspective on a traditional therapy. (4/231)

Update on the treatment of systemic lupus erythematosus: therapeutic highlights from the Sixth International Lupus Conference. (5/231)

The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced nonsmall cell lung carcinoma: potential for decreased toxicity and combination with biological therapy. (6/231)

Yoghurt biotherapy: contraindicated in immunosuppressed patients? (7/231)

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker. (8/231)

Biological Therapy

Biological Products

Antirheumatic Agents

Arthritis, Rheumatoid

Phenetidine

Antibodies, Monoclonal

Psoriasis

Arthritis, Psoriatic

Antibodies, Monoclonal, Humanized

Immunologic Factors

Dermatologic Agents

Spondylarthritis

Receptors, Tumor Necrosis Factor

Rheumatic Diseases

Antibodies, Monoclonal, Murine-Derived

Tumor Necrosis Factor-alpha

Off-Label Use

Schizophrenia, Catatonic

Gastrointestinal Agents

Anti-Inflammatory Agents

Treatment Outcome

Inflammatory Bowel Diseases

Crohn Disease

Immunoglobulin G

Immunosuppressive Agents

Immunotherapy

Clinical Trials as Topic

Immunoconjugates

Autoimmune Diseases

Arthritis, Juvenile

Neoplasms

Severity of Illness Index

Spondylitis, Ankylosing

Methotrexate

Interleukin 1 Receptor Antagonist Protein

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Clinical Trials, Phase III as Topic

Antineoplastic Combined Chemotherapy Protocols

Clinical Trials, Phase II as Topic

Nuclear Reprogramming

Breast Neoplasms

Antineoplastic Agents, Hormonal

Tamoxifen

Oncogenes

Breast

Lymphoma, Non-Hodgkin

Canada

American Cancer Society

Lymphoma

Hepatitis B Surface Antigens

Blood Urea Nitrogen

Platelet Count

Nuclear Medicine

Carcinoma, Lobular

New treatment strategies for malignant gliomas. (1/231)

Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. (2/231)

Where is biological therapy going? (3/231)

Probiotic agents and infectious diseases: a modern perspective on a traditional therapy. (4/231)

Update on the treatment of systemic lupus erythematosus: therapeutic highlights from the Sixth International Lupus Conference. (5/231)

The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced nonsmall cell lung carcinoma: potential for decreased toxicity and combination with biological therapy. (6/231)

Yoghurt biotherapy: contraindicated in immunosuppressed patients? (7/231)

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker. (8/231)

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Biological therapies in the systemic management of psoriasis: International Consensus Conference - Psoriasis Info

Biological therapy for cancer - Tests & Procedures

Bladder Cancer Biological Therapy India,Cost Biological Therapy India

Biological therapy for non-Hodgkin lymphoma - Canadian Cancer Society

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Treating Clostridium difficile infection with fecal microbiota transplantation. - PubMed - NCBI

Should Your Fecal Microbiota Transplantation Study Use Germ-Free Mice? | Taconic Biosciences

Search results for `Xiao Yunxiao` - PhilPapers

Treating Feline Inflammatory Bowel Disease With Fecal Microbiota Transplantation - PoC

$Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease | Blood...$ Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease | Blood...