The privacy of information and its protection against unauthorized disclosure.
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
Facilities that collect, store, and distribute tissues, e.g., cell lines, microorganisms, blood, sperm, milk, breast tissue, for use by others. Other uses may include transplantation and comparison of diseased tissues in the identification of cancer.
Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.
Component of the NATIONAL INSTITUTES OF HEALTH. Through basic and clinical biomedical research and training, it conducts and supports research with the objective of cancer prevention, early stage identification and elimination. This Institute was established in 1937.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.
The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
Centers for acquiring, characterizing, and storing organs or tissue for future use.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
The study of the origin, structure, development, growth, function, genetics, and reproduction of organisms which inhabit the OCEANS AND SEAS.
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
Enzymes of the transferase class that catalyze the transfer of a pentose group from one compound to another.
A publication issued at stated, more or less regular, intervals.
A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). The sandfly genera Phlebotomus and Lutzomyia are the vectors.
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)
A stack of flattened vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough ENDOPLASMIC RETICULUM and directing them to secretory vesicles, LYSOSOMES, or the CELL MEMBRANE. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus and fuse with the Golgi, lysosomes or cell membrane. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990)
Exclusive legal rights or privileges applied to inventions, plants, etc.
A type of TRANSMISSION ELECTRON MICROSCOPY in which the object is examined directly by an extremely narrow electron beam scanning the specimen point-by-point and using the reactions of the electrons that are transmitted through the specimen to create the image. It should not be confused with SCANNING ELECTRON MICROSCOPY.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Elements of limited time intervals, contributing to particular results or situations.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
The systematic study of the complete DNA sequences (GENOME) of organisms.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
A subdiscipline of human genetics which entails the reliable prediction of certain human disorders as a function of the lineage and/or genetic makeup of an individual or of any two parents or potential parents.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.
The activities and endeavors of the public health services in a community on any level.
The state of legal insolvency with assets taken over by judicial process so that they may be distributed among creditors.
Financial support for training including both student stipends and loans and training grants to institutions.
Research that involves the application of the natural sciences, especially biology and physiology, to medicine.
Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
Tumors or cancer of the UTERINE CERVIX.
A type of ALPHAPAPILLOMAVIRUS especially associated with malignant tumors of the CERVIX and the RESPIRATORY MUCOSA.
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
A type of human papillomavirus especially associated with malignant tumors of the genital and RESPIRATORY MUCOSA.
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
Ruminants of the family Bovidae consisting of Bubalus arnee and Syncerus caffer. This concept is differentiated from BISON, which refers to Bison bison and Bison bonasus.
The technique of using a microtome to cut thin or ultrathin sections of tissues embedded in a supporting substance. The microtome is an instrument that hold a steel, glass or diamond knife in clamps at an angle to the blocks of prepared tissues, which it cuts in sections of equal thickness.
Directory signs or listings of designated areas within or without a facility.
A mixture of solid hydrocarbons obtained from petroleum. It has a wide range of uses including as a stiffening agent in ointments, as a lubricant, and as a topical anti-inflammatory. It is also commonly used as an embedding material in histology.
Coloring matter from the insect Coccus cacti L. It is used in foods, pharmaceuticals, toiletries, etc., as a dye, and also has use as a microscopic stain and biological marker.
Procedures, strategies, and theories of planning.

Accessory DNA in the genomes of representatives of the Escherichia coli reference collection. (1/285)

Different strains of the Escherichia coli reference collection (ECOR) differ widely in chromosomal size. To analyze the nature of the differential gene pool carried by different strains, we have followed an approach in which random amplified polymorphic DNA (RAPD) was used to generate several PCR fragments. Those present in some but not all the strains were screened by hybridization to assess their distribution throughout the ECOR collection. Thirteen fragments with various degrees of occurrence were sequenced. Three of them corresponded to RAPD markers of widespread distribution. Of these, two were housekeeping genes shown by hybridization to be present in all the E. coli strains and in Salmonella enterica LT2; the third fragment contained a paralogous copy of dnaK with widespread, but not global, distribution. The other 10 RAPD markers were found in only a few strains. However, hybridization results demonstrated that four of them were actually present in a large selection of the ECOR collection (between 42 and 97% of the strains); three of these fragments contained open reading frames associated with phages or plasmids known in E. coli K-12. The remaining six fragments were present in only between one and four strains; of these, four fragments showed no similarity to any sequence in the databases, and the other two had low but significant similarity to a protein involved in the Klebsiella capsule synthesis and to RNA helicases of archaeal genomes, respectively. Their percent GC, dinucleotide content, and codon adaptation index suggested an exogenous origin by horizontal transfer. These results can be interpreted as reflecting the presence of a large pool of strain-specific genes, whose origin could be outside the species boundaries.  (+info)

Intraspecific diversity of the 23S rRNA gene and the spacer region downstream in Escherichia coli. (2/285)

The molecular microevolution of the 23S rRNA gene (rrl) plus the spacer downstream has been studied by sequencing of different operons from some representative strains of the Escherichia coli ECOR collection. The rrl gene was fully sequenced in six strains showing a total of 67 polymorphic sites, a level of variation per nucleotide similar to that found for the 16S rRNA gene (rrs) in a previous study. The size of the gene was highly conserved (2902 to 2905 nucleotides). Most polymorphic sites were clustered in five secondary-structure helices. Those regions in a large number of operons were sequenced, and several variations were found. Sequences of the same helix from two different strains were often widely divergent, and no intermediate forms existed. Intercistronic variability was detected, although it seemed to be lower than for the rrs gene. The presence of two characteristic sequences was determined by PCR analysis throughout all of the strains of the ECOR collection, and some correlations with the multilocus enzyme electrophoresis clusters were detected. The mode of variation of the rrl gene seems to be quite similar to that of the rrs gene. Homogenization of the gene families and transfer of sequences from different clonal lines could explain this pattern of variation detected; perhaps these factors are more relevant to evolution than single mutation. The spacer region between the 23S and 5S rRNA genes exhibited a highly polymorphic region, particularly at the 3' end.  (+info)

Mouse ENU mutagenesis. (3/285)

The progress of human genome sequencing is driving genetic approaches to define gene function. Strategies such as gene traps and chemical mutagenesis will soon generate a large mutant mouse resource. Point mutations induced by N -ethyl- N -nitrosourea (ENU) provide a unique mutant resource because they: (i) reflect the consequences of single gene change independent of position effects; (ii) provide a fine-structure dissection of protein function; (iii) display a range of mutant effects from complete or partial loss of function to exaggerated function; and (iv) discover gene functions in an unbiased manner. Phenotype-driven ENU screens in the mouse are emphasizing relevance to human clinical disease by targeting cardiology, physiology, neurology, immunity, hematopoiesis and mammalian development. Such approaches are extremely powerful in understanding complex human diseases and traits: the base-pair changes may accurately model base changes found in human diseases, and subtle mutant alleles in a standard genetic background provide the ability to analyze the consequences of compound genotypes. Ongoing mouse ENU mutagenesis experiments are generating a treasure trove of new mutations to allow an in-depth study of a single gene, a chromosomal region or a biological system.  (+info)

Distribution of intervening sequences in the genes for 23S rRNA and rRNA fragmentation among strains of the Salmonella reference collection B (SARB) and SARC sets. (4/285)

Intervening sequences (IVSs) occur sporadically in several bacterial genera in the genes for 23S rRNA at relatively conserved locations. They are cleaved after transcription and lead to the presence of fragmented rRNA, which is incorporated into the ribosomes without religation but is nevertheless functional. The fragmentation of rRNA and the number of IVSs in all 72 strains of the Salmonella Reference Collection B set and 16 strains of the Salmonella Reference Collection C set, which have been established on the basis of multilocus enzyme electrophoresis (MLEE), were analyzed in the present study. Fragmentation of 23S rRNA was restricted to conserved cleavage sites located at bp 550 (helix 25) and bp 1170 (helix 45), locations where IVSs have been reported. Random cleavage at sites where IVSs could not be detected was not seen. Uncleaved IVSs were not detected in any case; thus, the IVSs invariably led to rRNA fragmentation, indicating a strong selection for maintenance of RNase III cleavage sites. The distribution of the number of IVSs carried by the different strains in the seven rrl genes is diverse, and the pattern of IVS possession could not be related to the MLEE pattern among the various Salmonella strains tested; this indicates that the IVSs are frequently exchanged between strains by lateral transfer. All eight subspecies of the genus Salmonella, including subspecies V represented by Salmonella bongori, have IVSs in both helix 25 and helix 45; this indicates that IVSs entered the genus after its divergence from Escherichia coli (more than 100 million years ago) but before separation of the genus Salmonella into many forms or that they were in the ancestor but have been lost from Escherichia.  (+info)

Differences in genotypes of Helicobacter pylori from different human populations. (5/285)

DNA motifs at several informative loci in more than 500 strains of Helicobacter pylori from five continents were studied by PCR and sequencing to gain insights into the evolution of this gastric pathogen. Five types of deletion, insertion, and substitution motifs were found at the right end of the H. pylori cag pathogenicity island. Of the three most common motifs, type I predominated in Spaniards, native Peruvians, and Guatemalan Ladinos (mixed Amerindian-European ancestry) and also in native Africans and U.S. residents; type II predominated among Japanese and Chinese; and type III predominated in Indians from Calcutta. Sequences in the cagA gene and in vacAm1 type alleles of the vacuolating cytotoxin gene (vacA) of strains from native Peruvians were also more like those from Spaniards than those from Asians. These indications of relatedness of Latin American and Spanish strains, despite the closer genetic relatedness of Amerindian and Asian people themselves, lead us to suggest that H. pylori may have been brought to the New World by European conquerors and colonists about 500 years ago. This thinking, in turn, suggests that H. pylori infection might have become widespread in people quite recently in human evolution.  (+info)

Cancer gene discovery using digital differential display. (6/285)

The Cancer Gene Anatomy Project database of the National Cancer Institute has thousands of expressed sequences, both known and novel, in the form of expressed sequence tags (ESTs). These ESTs, derived from diverse normal and tumor cDNA libraries, offer an attractive starting point for cancer gene discovery. Using a data-mining tool called Digital Differential Display (DDD) from the Cancer Gene Anatomy Project database, ESTs from six different solid tumor types (breast, colon, lung, ovary, pancreas, and prostate) were analyzed for differential expression. An electronic expression profile and chromosomal map position of these hits were generated from the Unigene database. The hits were categorized into major classes of genes including ribosomal proteins, enzymes, cell surface molecules, secretory proteins, adhesion molecules, and immunoglobulins and were found to be differentially expressed in these tumorderived libraries. Genes known to be up-regulated in prostate, breast, and pancreatic carcinomas were discovered by DDD, demonstrating the utility of this technique. Two hundred known genes and 500 novel sequences were discovered to be differentially expressed in these select tumor-derived libraries. Test genes were validated for expression specificity by reverse transcription-PCR, providing a proof of concept for gene discovery by DDD. A comprehensive database of hits can be accessed at http:// www.fau.edu/cmbb/publications/cancergenes. htm. This solid tumor DDD database should facilitate target identification for cancer diagnostics and therapeutics.  (+info)

exl, an exchangeable genetic island in Neisseria meningitidis. (7/285)

The genetic structure and evolution of a novel exchangeable meningococcal genomic island was defined for the important human pathogen Neisseria meningitidis. In 125 meningococcal strains tested, one of three unrelated nucleotide sequences, designated exl (exchangeable locus), was found between a gene required for heme utilization, hemO, and col, encoding a putative Escherichia coli collagenase homologue. The 5' boundary of each exl cassette was the stop codon of hemO, whereas the 3' boundary was delineated by a 33-bp repeat containing neisserial uptake sequences located downstream of col. One of the three alternative exl cassettes contained the meningococcal hemoglobin receptor gene, hmbR (exl3). In other meningococcal strains, hmbR was absent from the genome and was replaced by either a nucleotide sequence containing a novel open reading frame, exl2, or a cassette containing exl3. The proteins encoded by exl2 and exl3 had no significant amino acid homology to HmbR but contained six motifs that are also present in the lipoprotein components of the lactoferrin (LbpB), transferrin (TbpB), and hemoglobin-haptoglobin (HpuA) uptake systems. To determine the evolutionary relationships among meningococci carrying hmbR, exl2, or exl3, isolates representing 92 electrophoretic types were examined. hmbR was found throughout the population structure of N. meningitidis (genetic distance, >0.425), whereas exl2 and exl3 were found in clonal groups at genetic distances of <0.2. The commensal neisserial species were identified as reservoirs for all of the exl cassettes found in meningococci. The structure of these cassettes and their correlation with clonal groups emphasize the extensive gene pool and frequent horizontal DNA transfer events that contribute to the evolution and virulence of N. meningitidis.  (+info)

Recent events and observations pertaining to smallpox virus destruction in 2002. (8/285)

To destroy all remaining stocks of variola virus on or before 31 December 2002 seems an even more compelling goal today than it did in 1999, when the 52d World Health Assembly authorized temporary retention of remaining stocks to facilitate the possible development of (1) a more attenuated, less reactogenic smallpox vaccine and (2) an antiviral drug that could be used in treatment of patients with smallpox. We believe the deadline established in 1999 should be adhered to, given the potential outcomes of present research. Although verification that every country will have destroyed its stock of virus is impossible, it is reasonable to assume that the risk of a smallpox virus release would be diminished were the World Health Assembly to call on each country to destroy its stocks of smallpox virus and to state that any person, laboratory, or country found to have virus after date x would be guilty of a crime against humanity.  (+info)

TY - JOUR. T1 - Cohort profile. T2 - Design and methods in the eye and vision consortium of UK Biobank. AU - UK Biobank Eye and Vision Consortium. AU - Chua, Sharon Yu Lin. AU - Thomas, Dhanes. AU - Allen, Naomi. AU - Lotery, Andrew. AU - Desai, Parul. AU - Patel, Praveen. AU - Muthy, Zaynah. AU - Sudlow, Cathie. AU - Peto, Tunde. AU - Khaw, Peng Tee. AU - Foster, Paul J.. AU - Trucco, Emanuele. PY - 2019/2/21. Y1 - 2019/2/21. N2 - Purpose To describe the rationale, methods and research potential of eye and vision measures available in UK Biobank. Participants UK Biobank is a large, multisite, prospective cohort study. Extensive lifestyle and health questionnaires, a range of physical measures and collection of biological specimens are collected. The scope of UK Biobank was extended midway through data collection to include assessments of other measures of health, including eyes and vision. The eye assessment at baseline included questionnaires detailing past ophthalmic and family history, ...
This fact sheet provides information for NHS, Health Professionals Follow-up Study (HPFS), and Growing Up Today Study (GUTS) participants with biospecimens in the Brigham and Womens Hospital (BWH) / Harvard Cohorts Biorepository. Overview Thank you for participating in the BWH/Harvard Cohorts Biorepository. This fact sheet provides more information about the biorepository.
UK Biobank aims to assess the relevance of a very wide range of health-related outcomes. It is a large prospective study to investigate the role of genetic factors, environmental exposures and lifestyle in the causes of major diseases of late and middle age. During 2006-2010, UK Biobank conducted its recruitment phase of more than 500,000 participants who gave their consent, answered questions, had physical measurements and gave samples (blood, urine and saliva) at a Baseline assessment visit. Follow-up of their health is now being conducted through medical and other health-related records. Access systems have been developed to facilitate use of the UK Biobank Resource by bona fide researchers for health-related research that is in the public interest ...
Biospecimens collected by the CONCERT Biobank are made available to researchers on the provision that use of specimens are for scientifically valid and ethically approved research projects.. Researcher access entails search facilities which allow for researchers to search biospecimen type and availability stored in the CONCERT Biobank using a link from the CONCERT TCRC website to the Biobanks database, which is currently still under development. All biospecimens and information are stored securely and de-identified however they are re-identifiable to CONCERT Biobank personnel who have signed confidentially agreements. Search facilities on the database protect all identifiable information of the participant.. Currently, as the CONCERT Biobank is still in the progress of developing and implementing its database, researchers can request the use of biospecimens by contacting the CONCERT Biobank manager through the Ingham Institute for Applied Medical Researchs Biobank page, ...
The goal of personalized medicine has ushered in the transition from empirical medicine to molecular medicine. Thus during research, biobanks are key infrastructures for biomedical R& D because at one time or another, these biospecimens have been stored in a biobank. Well-annotated biospecimens and their associated clinical data accelerate translational and clinical research discoveries. However, high-throughput molecular sequencing and increased biosample variety have introduced significant informatics challenges for biobanking infrastructures. Meanwhile, the lack of high-quality biospecimens both stalls projects and limits research advances. Cambridge Healthtech Institutes Ninth International Leaders in Biobanking Congress addresses biospecimen science, management, and applications, bringing together biomedical and biopharmaceutical researchers, regulators, biorepository managers and practitioners to investigate the best strategies for effective use of biospecimens within todays cutting-edge
How Biorepositories Can Help Your Research. Tatiana Foroud, Ph.D. Department of Medical and Molecular Genetics. Overview. Sample collection for genetic studies Typical DNA applications for genetic studies Results from several ongoing studies. Collecting Samples for Genetic Studies. Slideshow 6743902 by dominica-ronnie
In this webinar, we briefly discussed the regulatory considerations for biorepositories including the following: When HHS, FDA and HIPAA regulations apply, Whe…
Given the importance of results discovered by biorepositories and their implications for an individuals health care choices, I believe that the individual has the right to receive his results despite their lack of verification. However, this right to receive results should be premised upon the individuals explicit consent to receive his results, and upon the understanding that by receiving these results, the burden of their verification shifts from the biorepostory to the individual.. Biorepositories are collections of biospecimens that are tested and analyzed for scientific purposes. The testing performed on these biospecimens has become the basis for development of various molecular tests, which is becoming critical for the shift toward personalized medicine. Therefore, as technology advances, the quality and management of biorepositories is becoming more important. This is especially critical for the return of accurate patient data resulting from biospecimen analysis. However, managing and ...
Medical imaging has enormous potential for early disease prediction, but is impeded by the difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to address this problem directly by acquiring high-quality, consistently acquired imaging data from 100,000 predominantly healthy participants, with health outcomes being tracked over the coming decades. The brain imaging includes structural, diffusion and functional modalities. Along with body and cardiac imaging, genetics, lifestyle measures, biological phenotyping and health records, this imaging is expected to enable discovery of imaging markers of a broad range of diseases at their earliest stages, as well as provide unique insight into disease mechanisms. We describe UK Biobank brain imaging and present results derived from the first 5,000 participants data release. Although this covers just 5% of the ultimate cohort, it has already yielded a rich range of associations between brain imaging and other measures collected by UK
Medical imaging has enormous potential for early disease prediction, but is impeded by the difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to address this problem directly by acquiring high-quality, consistently acquired imaging data from 100,000 predominantly healthy participants, with health outcomes being tracked over the coming decades. The brain imaging includes structural, diffusion and functional modalities. Along with body and cardiac imaging, genetics, lifestyle measures, biological phenotyping and health records, this imaging is expected to enable discovery of imaging markers of a broad range of diseases at their earliest stages, as well as provide unique insight into disease mechanisms. We describe UK Biobank brain imaging and present results derived from the first 5,000 participants data release. Although this covers just 5% of the ultimate cohort, it has already yielded a rich range of associations between brain imaging and other measures collected by UK
UK Biobank is a prospective cohort study with 500,000 participants aged 40 to 69. Recently an enhanced imaging study received funding. Cardiovascular magnetic resonance (CMR) will be part of a multi-organ, multi-modality imaging visit in 3-4 dedicated UK Biobank imaging centres that will acquire and
1. Dekkers IA, Jansen PR, Lamb HJ. Obesity, Brain Volume, and White Matter Microstructure at MRI: A Cross-sectional UK Biobank Study. Radiology. 2019 Apr 23:181012.. 2. Hwang LD, Lin C, Gharahkhani P, Cuellar-Partida G, Ong JS, An Gordon SD, Zhu G, MacGregor S, Lawlor DA, Breslin PAS, Wright MJ, Martin NG, Reed DR. New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances. Am J Clin Nutr. 2019 Apr 21. pii: nqz043.. 3. Machado-Fragua MD, Struijk EA, Ballesteros JM, Ortolá R, Rodriguez Artalejo F, Lopez-Garcia E. Habitual coffee consumption and risk of falls in 2 European cohorts of older adults. Am J Clin Nutr. 2019 Apr 21. pii: nqy369.. 4. Hajna S, White T, Panter J, Brage S, Wijndaele K, Woodcock J, Ogilvie D, Imamura F, Griffin SJ. Driving status, travel modes and accelerometer assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants. Int J Epidemiol. 2019 Apr 19. pii: ...
From managing the storage and maintenance of annotated specimen data to following the chain of custody and making determinations about a sample quickly and accurately, a biobanking LIMS requires standard features to meet the needs of the community.. At LabVantage, for example, we designed our biobanking LIMS to address these concerns using a centralized LIMS for efficient, accurate, and secure tracking of biobank samples and consents.. Want to learn more? Read our latest article in Genetic Engineering & Biotechnology News.. Interested in learning how a LIMS built specifically for Biobanking can better support your organization by tearing down your data silos and maximizing the insights you draw from your biobank data? Contact us today.. ...
Biobanking strategies and regulative approaches in the EU: recent perspectives Katharina Beier,1 Christian Lenk2 1Department of Medical Ethics and History of Medicine, University Medical Center Göttingen, Göttingen, Germany; 2Institute of the History, Philosophy, and Ethics of Medicine, Ulm University, Ulm, Germany Abstract: Biobanks, ie, systematic collections of human biological materials and associated clinical and lifestyle data, provide an indispensable infrastructure for modern research. Although biobank research takes place on a global scale, there is no internationally binding framework for its ethical and legal regulation yet. A better understanding of existing regulative approaches is an important prerequisite for its ethical and legal harmonization and, thus, for improving the interoperability of biobank-based research in the future. This review focuses on biobanking strategies, regulative approaches, and recent developments in Europe. Specifically, we discuss selected ethical and
Biobank consent models – are we moving toward increased participant engagement in biobanking? Berge Solberg, Kristin Solum Steinsbekk Department of Public Health and General Practice, Norwegian University of Science and Technology (NTNU), Trondheim, Norway Abstract: Engagement, involvement, and active participation are buzzwords used in today's ethical debate on research biobanking. There are a variety of context-sensitive governance frameworks for research biobanks. However, many biobanks, especially large-scale population-based ones, seem to endorse a framework of broad consent, participation with minimal or no ongoing engagement, and no return of results. An alternative vision of involvement and active participation in this type of research has become increasingly visible in the literature. The problem, seen from the biobankers' perspective, is that the alternative vision might be costly, cumbersome, and risky, while the prevailing system for governance will maximize the scientific
There are several characteristics of COLS that differentiate it from existing repositories.. First, most biobanks are created to study a given disease and consist of samples from ill patients. In contrast, COLS is disease inclusive by design. Many participants will be well when they enter the study; although, some will have chronic diseases at the outset. COLS will continue collecting samples for a decade. As people become ill that data will be captured in the bank. Therefore, both rare and common diseases will be represented over time because of the size of the cohort.. Second, COLS is omics exhaustive; that is blood and urine will be collected and stored in a way that preserves multiple molecules. Most biobanks are designed to preserve only one molecule, most commonly DNA. Previously, the dogma was that the genome was the key to understanding health and disease. We now understand that most diseases cannot be explained solely by ones genome, but instead by dynamic changes in molecules such as ...
CTSI Biorepository Biospecimen collection, processing and storage. Stored biospecimens can be used by any researcher with IRB approved protocols. Prospective biospecimen collection to fulfill investigator needs for IRB approved protocols. Storage for biospecimens collected by investigators. Stored biospecimens belong solely to the investigator. Oversight of the release of biospecimens from the UF Department of Pathology for other IRB approved research protocols. Pathology services including those provided by the Molecular Pathology Core and confirmation of diagnosis by a board certified pathologist upon request. The UF CTSI is supported in part by NIH awards UL1 TR000064, KL2 TR000065 and TL1 TR000066 One of two Hamilton 80 C automated sample management systems (Robotic freezers ). The biorepository also has eight Forma Thermo Scientific 80 C Freezers with back up CO 2 and sensaphone alarm systems including back up storage space, centrifuge for basic bodily fluid processing, QiaCube for small ...
How many clinics in Texas market stem cell procedures? What interventions do they promote? How many adult stem cell banks are located in Texas? How do they advertise their services?. There does not appear to be a comprehensive record of stem cell banks and clinics marketing stem cell procedures within the state of Texas. I am therefore trying to determine how many stem cell banks and clinics marketing stem cells in Texas can be found using an approach that a patient or customer might take when searching the Internet. In an effort to locate such businesses, I used Google search engine and entered such terms as stem cells Texas, stem cell clinics Texas, cosmetic surgery stem cell Texas, orthopedic surgery stem cell clinic Texas, and anti-aging stem cells Texas. In total, I found twenty businesses marketing what they describe as stem cell procedures as well as three stem cell banks. During my search I also noticed and recorded a spa marketing plant stem cells and a dentist who ...
The overall goal of this project is to identify strategies to reduce lung cancer incidence and mortality. Using a high-risk occupational cohort, our specific objectives are 1) to establish a biologic specimen bank and data bank that can be used for the validation and refinement of potential early markers of lung cancer, and 2) to establish a cohort for the study of environmental (including dietary) and genetic risk factors for lung cancer.. Lung cancer is the leading cause of death from malignant neoplasms in the United States and in many countries around the world. Potential strategies to reduce the incidence and mortality of lung cancer include new methods of early detection and identification and alteration of etiologic factors.. The Yunnan Tin Corporation (YTC), located in Yunnan Province in southern China, is a large, nonferrous-metals industry, formed in 1883 and nationalized after the establishment of the Peoples Republic in 1949. It is involved principally in the production of tin from ...
Moffitt Cancer Center and M2Gen have been awarded a contract from the National Institutes of Healths National Heart, Lung, and Blood Institute to serve as the Central Laboratory and Biorepository for The National Myelodysplastic Syndromes Natural History Study (The National MDS Study).
ProteoGenex has a centralized biorepository of over 200,000 human clinical specimens in a wide variety of formats (FFPE & Frozen Tissues, Serum/Plasma, etc)
The Massachusetts General Hospital Cardiovascular Biorepository (CVBio) advances cardiovascular research by providing patient data and blood samples to help researchers understand how genes and other factors contribute to heart disease.
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: National Gene Vector Biorepository and Coordinating Center (P40) RFA-RR-07-002. NCRR
The Biorepository and Pathology CoRE is a multi-dimensional service group providing consultation and technical support for the translational and basic science groups across MSHS.
Rogena, J., Kihara, A. and Kemp, S. 2014. Monitoring ILRIs biorepository. Poster presented at the 50th Anniversary Celebration and Annual Scientific Conference for the Society of Low Temperature Biology, London, UK, 8-10 October 2014 ...
Biobanking 2018 will bring together the worlds leading experts in biorepositories, policy makers, and scientific actors to strengthen knowledge in biobanking as well as explore future advances in the field of biosampling for precision medicine, drug development and health research.
Biorepositories are highly complex research facilities with expert staff to process, store, characterize and secure biological specimens and their corresponding clinical information. The Biopathology Center at Nationwide Childrens Hospital, the hospitals long-standing biorepository, has received accreditation from the College of American Pathologists, confirming that the biorepository operates to ensure that high-quality biospecimens and related data are available for the purpose of supporting cutting-edge medical research.
The aim of this thesis is to investigate the relationship between individuals and society in the context of healthcare and medical research, more specifically concerning the rights and duties of individuals in regard to biobank-based research. My starting point is that we all have a strong vested interest in improved healthcare, and therefore the possibilities to conduct important research should be optimized. In the first article, I investigate whether individual results from research using samples in large-scale biobanks should be returned. I conclude that there is good reason not to implement such policies, and instead to allocate available resources to pursuing medical advances. In the second article, I compare consent for using stored samples in research with consent for organ donation, whereby many countries have adopted opt-out strategies in order to increase the number of organs available. I claim that the default position should be changed in biobank research as well, i.e. it should be ...
Carolinas HealthCare System recently created a BioSpecimen Repository on its Mint Hill campus, which will ultimately enhance researchers understanding of how to more effectively treat a broad range of diseases. Carol J. Farhangfar, PhD, MBA, Assistant Vice President of Carolinas HealthCare Systems Tissue Procurement and Levine Cancer Institutes Translational Research, is overseeing the development of the Repository and discusses its significance for providers and patients. Q: Why was the Biospecimen Repository created at CHS, and how will it enhance our research efforts? The BioSpecimen Repository (BSR) was created at CHS to provide a comprehensive, enterprise-wide system to collect, process, store, and distribute high quality biospecimens for clinical and translational research. It will enhance the capabilities of dedicated CHS investigators and enable the evolution of CHS into a nationally recognized clinical service provider that can leverage tissues and other biospecimens to help us ...
Biobanks are an important resource for the research and development of cell and gene therapies, but biobanking requires the careful consideration of ethics and patient privacy, and carries issues around lack of inclusion of ethnic minorities. Furthermore, biobanks for cell therapies are still in their infancy in terms of potential to have a significant impact on healthcare: large, clinical-grade banks of cells, whether induced pluripotent stem cells or other, with diverse genetic backgrounds will be needed for widespread clinical application of cellular therapies. This channel includes content around all these different aspects, including the latest news and opinion, and top peer-reviewed articles.
Abstract Finland has enacted a Biobank Act that will come into force on 1 September 2013. Finland is regarded as a highly successful environment for medical research using population samples and data for many reasons. One of the rationales behind the new legislation was to solve the problems due to the overly strict informed consent doctrine hindering access to old samples and data and asking for multi-purpose consents. Yet although consent is the primary justification to use biobank samples and data, the Biobank Act allows asking for a consent for several unspecified future research purposes. The guiding principles of the Biobank Act are promotion of trust, equal access to data and samples, protection of privacy, acceleration of innovation activities, and bringing biobank activities under public scrutiny. To the authors knowledge, this is the first
OBJECTIVE: To estimate the effect of BMI on cause-specific hospital admissions and costs in men and women is not well understood, and this studys aim is to address this. METHODS: For 451,320 men and women aged 40 years or older recruited into the UK Biobank, followed up for 6 years on average, this study estimated annual rates and costs (at 2016 UK prices) of hospital admissions, overall and by diagnostic category (using International Classification of Diseases, Tenth Revision chapters), in relation to BMI. RESULTS: Among those who were never smokers, a 2-kg/m2 higher BMI (above 20 kg/m2 ) was associated with a 6.2% (99% CI: 5.3% to 7.2%) higher admission rate and an 8.6% (99% CI: 7.3% to 10.0%) higher annual cost in men and with a 5.7% (99% CI: 4.9% to 6.6%) higher admission rate and an 8.4% (99% CI: 7.5% to 9.3%) higher annual cost in women. Higher BMI was associated with higher admission rates and costs for many types of health conditions, particularly for endocrine, skin, and musculoskeletal
We investigated the association between genetic risk of stroke, lifestyle, and incident risk of stroke in 306 473 people within the population based UK Biobank study. Risk of incident stroke was 35% higher among those at high genetic risk compared with those at low genetic risk, and these associations were independent of lifestyle profile. Furthermore, an unfavourable lifestyle was associated with a 66% increased risk of incident stroke compared with a favourable lifestyle, and this increased risk was present within any genetic risk category. A high genetic risk combined with an unfavourable lifestyle profile was associated with a more than twofold increased risk of stroke compared with a low genetic risk and a favourable lifestyle.. The present study provides further support that common genetic variants are implicated in the development of stroke. Our findings showing that a polygenic risk score is associated with incident stroke is in line with both clinical and population based ...
Context: UK Biobank is a prospective study of half a million subjects, almost all aged 40-69 years, identified in 22 centres across the UK during 2006-2010. Objective: A healthy lifestyle has been described as better than any pill, and no side effects [5]. We therefore examined the relationships between healthy behaviours: low alcohol intake, non-smoking, healthy BMI, physical activity and a healthy diet, and the risk of all cancers, colon, breast and prostate cancers in a large dataset. Method: Data on lifestyle behaviours were provided by 343,150 subjects, and height and weight were measured at recruitment. 14,285 subjects were diagnosed with cancer during a median of 5.1 years of follow-up. Results: Compared with subjects who followed none or a single healthy behaviour, a healthy lifestyle based on all five behaviours was associated with a reduction of about one-third in incident cancer (hazard ratio [HR] 0.68; 95% confidence intervals [CI] 0.63-0.74). Colorectal cancer was reduced in subjects
This is a full description of the quality control procedure undertaken and the derived files produced by the MRC-IEU associated with the full UK Biobank (July 2017) genetic data ...
Healthy living and cancer: evidence from UK Biobank Peter C Elwood1, Alex Whitmarsh1, John Gallacher2, Anthony Bayer1, Richard Adams3, Luke Heslop1
Health-care research relies largely on human materials stored in highly specialised biorepositories. Medical translational research on tissues can be performed using a variety of resources in distinct situations. The best known is the secondary use of pathology archives where paraffin-embedded tissues are stored for diagnostic reasons. Another is collecting and storing frozen material obtained from leftover surgical diagnosis. Such residual tissues can either be used directly in research projects or used in the context of a clinical trial with new interventional medicinal products. The latter can make the regulations governing the use of these materials for medical research much more complicated. The use of residual materials is very distinct from biobanking projects for which tissue is specifically collected. This article describes the consequences of using residual human material from different sources in distinct situations and why signed informed consent is not always the preferred choice of ...
Purpose: Biospecimens (e.g. tissues, bloods, fluids) are critical for translational cancer research to generate the necessary knowledge to guide implementation of precision medicine. Rising demand and the need for higher quality biospecimens are already evident. Methods: The recent increase in requirement for biospecimen complexity in terms of linked biospecimen types, multiple preservation formats, and longitudinal data was explored by assessing trends in cancer research publications from 2000 to 2014. Results: A Pubmed search shows that there has been an increase in both raw numbers and the relative proportion (adjusted for total numbers of papers in each period) of the subgroups of papers typically associated with the use of biospecimens and both dense treatment and/or outcomes data and multiple biospecimen formats. Conclusions: Increasing biospecimen complexity is a largely unrecognized and new pressure on cancer research biobanks. New approaches to cancer biospecimen resources are needed ...
Trans-Hit Bio is the worldwide biospecimen access CRO with the most extensive collection capability for biospecimens and clinical samples through an unrivaled worldwide partnered-network of state-of-the-art academic biorepositories and clinical sites.. ...
Trans-Hit Bio is the worldwide biospecimen access CRO with the most extensive collection capability for biospecimens and clinical samples through an unrivaled worldwide partnered-network of state-of-the-art academic biorepositories and clinical sites.. ...
Background: Coronary heart disease (CHD) poses a major health burden in the Gulf countries. Knowledge of novel genetic and proteomic markers of CHD will provide more precise estimates of risk while defining the pathways important in individual patients, revealing new targets for intervention, and ultimately enabling an individualized approach to care. We describe design of a biorepository with linkage to medical records to facilitate discovery of biomarkers for CHD. Methods: The goal of the Qatar Cardiovascular Biorepository (QCBio) is to archive plasma and DNA of 1000 Qatari patients with CHD and 1000 age, gender, and ethnicity-matched controls who have no history of CHD. Cases will include patients needing percutaneous intervention for symptomatic CHD or admitted with an acute coronary syndrome (myocardial infarction or unstable angina). Controls will be identified from the blood bank as adults who have no history of CHD. Relevant risk factors and comorbid conditions will be ascertained by electronic
In 2012, the College accredited RUDCR through its Biorepository Accreditation Program, making the operation at Rutgers one of the first in the world to earn this designation.. The program is intended to improve and validate the quality of biospecimens and biorepositories. It focuses on standardizing and improving the collection, processing, storage, and distribution of biospecimens, along with computerizing associated information. The program also is intended to ensure the quality of human specimens (e.g., blood, serum, saliva, tissue) and the genetic materials derived from them (e.g., DNA, RNA).. Were extremely pleased by this strong validation of our shared commitment to the highest levels of quality and service to the biomedical research community, said Jay A. Tischfield, Founder and Chief Executive Officer of RUCDR, Duncan and Nancy Macmillan Professor of Genetics, and Director of the Human Genetics Institute of New Jersey. There are thousands of biorepositories in the world, with a wide ...
US Biolab is a global biobank that have access to a diverse range of human biospecimens in various disease states to meet researchers research needs. Our biobank contains more than 500,000 huamn tissue (FFPE and fresh frozen), tissue array, serum, plasma, whole blood, DNA, and RNA samples. Our team collaborates with the major clinical and research center in the USA, Europe, and Asia on developing collection protocols that are approved by local IRBs and Ethical Committees and that comply with international and local regulations and guidelines. Our customers are major pharmaceutical and biotechnology companies as well as academic and government research organizations. Our samples are handled consistently according to validated protocol accommodate the quality requirements of most research methods used in the drug discovery and development process.. ...
TY - JOUR. T1 - Contrast-free microscopic assessment of glioblastoma bioposy specimens prior to biobanking. AU - Georges, Joseph. AU - Zehri, Aqib. AU - Carlson, Elizabeth. AU - Nichols, Joshua. AU - Mooney, Michael A.. AU - Martirosyan, Nikolay L.. AU - Ghaffari, Layla. AU - Kalani, M. Yashar S.. AU - Eschbacher, Jennifer. AU - Feuerstein, Burt. AU - Anderson, Trent. AU - Preul, Mark C.. AU - Van Keuren-Jensen, Kendall. AU - Nakaji, Peter. PY - 2014/2/26. Y1 - 2014/2/26. N2 - Glioblastoma is the most common primary brain tumor with a median 12- to 15-month patient survival. Improving patient survival involves better understanding the biological mechanisms of glioblastoma tumorigenesis and seeking targeted molecular therapies. Central to furthering these advances is the collection and storage of surgical biopsies (biobanking) for research. This paper addresses an imaging modality, confocal reflectance microscopy (CRM), for safely screening glioblastoma biopsy samples prior to biobanking to ...
Disposal of samples This issue was not addressed in Resolution CNS 347/05, although there are normative documents issued by National Agency for Sanitary Vigilance (ANVISA, Brasilia, Brazil) and the National Environmental Council (CONAMA, Brasilia, Brazil). The ACCHB and BNT-INCA currently discard samples due to inadequate quality. Samples may also be retrieved for additional diagnostic purposes or by consent-granted withdrawal. The possibility of bankruptcy also needs to be considered. It is illegal to sell biological human samples in Brazil, and biobanks like ACCHB and BNT-INCA are usually established with grant support from state, federal, and international funding agencies. However, as with biorepositories, such grants are limited in duration. In this case, both the Ministry of Health Ordinance No. 2201 and the Resolution CNS 441/11 state that, provided that the samples are adequate for research, their transfer to another institution should be considered, and destruction-in a manner not ...
BACKGROUND: With an estimated one billion hypertension cases worldwide, the role of the built environment in its prevention and control is still uncertain. The present study aims to examine the associations between neighbourhood walkability and hypertension in a large and diverse population-based cohort. MATERIALS AND METHODS: We examined the association between neighbourhood walkability and blood pressure outcomes for N = 429,334 participants drawn from the UK Biobank and aged 38-73 years. Neighbourhood walkability was objectively modelled from detailed building footprint-level data within multi-scale functional neighbourhoods (1.0-, 1.5- and 2.0-kilometer street catchments of geocoded dwelling). A series of linear and modified Poisson regression models were employed to examine the association between walkability and outcomes of diastolic blood pressure (DBP in mmHg), systolic blood pressure (SBP in mmHg) and prevalent hypertension adjusting for socio-demographic, lifestyle and related physical
Results 12 015 and 10 344 participants died during a median of 18.5 and 7.0 years of follow-up in the HUNT Study and UK Biobank, respectively. Linear mendelian randomisation analyses indicated an overall positive association between genetically predicted BMI and the risk of all cause mortality. An increase of 1 unit in genetically predicted BMI led to a 5% (95% confidence interval 1% to 8%) higher risk of mortality in overweight participants (BMI 25.0-29.9) and a 9% (4% to 14%) higher risk of mortality in obese participants (BMI ≥30.0) but a 34% (16% to 48%) lower risk in underweight (BMI ,18.5) and a 14% (−1% to 27%) lower risk in low normal weight participants (BMI 18.5-19.9). Non-linear mendelian randomisation indicated a J shaped relation between genetically predicted BMI and the risk of all cause mortality, with the lowest risk at a BMI of around 22-25 for the overall sample. Subgroup analyses by smoking status, however, suggested an always-increasing relation of BMI with mortality in ...
EPIC (European Prospective Investigation into Cancer and Nutrition) is a similar study that was started in 1992 and involves 520,000 men and women mostly between 35 and 70 years old from ten European countries. Participants are recontacted every three to five years. It is specifically designed to study the respective roles of diet and genes in the development of cancer.[11][39] In 1996 a private company deCODE genetics Inc. planned to obtain biobank samples, health and genealogical data from the whole population of Iceland - then about 270,000 people.[40] The company hoped to use the data to identify genes associated with diseases[41] and use that information to develop new drugs. deCODE genetics obtained data and DNA samples on 140,000 Icelanders[42] but filed for Chapter 11 bankruptcy in 2009[43] and as of January 2015 its systems and databanks had been spun off to another company NextCODE Health,[44] owned by WuXi PharmaTech.[45] In 2015, the Chief Executive of deCODE said that with the DNA ...
A capillary electrophoresis coupled to tandem mass spectrometry (CE-MS/MS) has been used to make a qualitative determination of hercynine-the main precursor of l-ergothioneine biosynthesis-in some key human biological specimens, such as urine, whole blood, plasma, and saliva. From semiquantitative analysis results, the highest concentrations of hercynine were detected in saliva and whole blood, whereas much lower concentrations were measured in urine and plasma. Whole blood was the biological matrix with the highest concentration of l-ergothioneine followed by plasma, saliva, and urine. The antioxidant effects attributed to l-ergothioneine, along with its peculiar antioxidant mechanism, offer a possible explanation for the presence of the hercynine, as well as its concentration, in the considered biological matrices ...
Dr. Katharine Hagerman and Lisa Harvey-Duren share their experience with the Stanford Biobank. Donating the tissue or other clinical specimens of a loved one will help advance treatments for myotonic dystrophy and provides hope that our family and friends will have a better future.
Introduction: Biobanks are repositories that store biospecimens and health information for research. Healthy control samples from diverse racial/ethnic groups must be represented in biobanks to better examine genetic and environmental risk factors for diseases such as cancer. However, the general public appears to be skeptical about the purpose of these repositories, with minority populations being less likely to donate samples. The Ponce School of Medicine-Moffitt Cancer Center Partnership conducted a study to examine communication channels for delivering biobanking education to healthy Hispanics. The purpose of this article is to describe the successful strategies used during the recruitment process.. Methods: The Outreach Core recruited community members (n=254) in Ponce, Puerto Rico and Tampa, Florida using a variety of in-person and media-based approaches. In-person strategies involved staffing booths at community events targeted to Hispanics such as health fairs, American Cancer Society ...
An overview is given of serum and urine prostate cancer markers that are currently under investigation and subsequently the P-Mark project is introduced. There are many markers showing promise to overcome the limitations of prostate specific antigen (PSA). Eventually, these markers should be able to increase the specificity in diagnosis, differentiate between harmless and aggressive disease and identify progression towards androgen independence at an early stage. In the P-Mark project, several recently developed, promising markers will be evaluated using clinically well-defined biorepositories. Following successful evaluation, these markers will be validated on a sample set derived from two large, European, prostate cancer studies and used for the identification of special risk groups in the general population. In addition, novel markers will be identified in the same biorepositories by different mass spectrometry techniques.
Stem cell bank. Labelled vials of embryonic stem cells at a stem cell bank, a place for storing the stem cells (by freezing) until they are needed. Stem cells are precursor cells from which all the bodys specialized tissue cells develop. Stem cell specialization can be initiated in the laboratory by the use of chemical growth factors. Stem cell research involves trying to use stem cells to repair or replace diseased tissues or organs. All the cells in young embryos are stem cells, and these cells were obtained from embryos that died of natural causes. Photographed at the Besta Neurological Institute, Milan, Italy. - Stock Image G442/0140
Last year the MCB Cell Bank obtained an authorization (PZ-T.04061.4.2015.ASI) from the Minister of Health for harvesting, processing, storing and distribution of human skin cells - keratinocytes, fibroblasts and melanocytes, human mezenchymal stem cells isolated from bone marrow and fat tissue, human chondrocytes isolated from cartilaginous tissue, human muscle cells, extracellular adipose matrix and we obtained also scientific recommendations on classification of our advanced therapy medicinal products from EMA which are required to obtain the approval of Main Pharmaceutical Inspectorate for production of the advanced therapy medicinal products with hospital exemption HE-ATMP. This year the MCB Cell Bank obtained the consent of the Main Pharmaceutical Inspectorate (GIF-IW-400/0490/01/460/UA2/15) for production of the advanced therapy medicinal products with hospital exemption HE-ATMP which include all mentioned above. ...
The Prostate Cancer Pathology Resource Network Award was established in 2009 to provide support for the development of a prostate cancer biorepository consortium that will facilitate the collection, processing, annotation, storage, and distribution of high-quality human prostate cancer biospecimens through a collaborative network across multiple institutions. The award is designed to support a biorepository that will enable the prostate cancer research community to address multiple areas of research such as biomarkers, therapy, genetics, and tumor biology to move toward the PCRP vision of conquering prostate cancer. FY13 Prostate Cancer Pathology Resource Network Awards. ...
The study of multifactorial diseases, such as vitiligo, requires analysis of complex interplay of symptoms, treatments and outcomes across a large number of people. Population surveys and biobanks are indispensable research tools, required for downstream therapy development. Even small collections of biosamples may be extremely precious for researcher in academic institution or biopharma company.. Until recently, vitiligo researchers were generally limited to conducting studies on patient samples they could acquire themselves. When the Foundation started there were no centralized biological database along with the pre-existing body of the clinical management or the historical study data, which is required in order to proceed with the development of specific therapies. We have run a special investigation study to determine whether VRF shall establish its own biobank.. Then the projects leadership crafted a careful strategy for vitiligo biobank development, with special attention paid to the ...
Mitochondrial diseases comprise a group of relatively rare (~1 in 5000 adults) but very serious genetic disorders. Mitochondria are often called the powerhouses of the cell because they provide the energy our cells need to live. Mitochondria have their own DNA (mtDNA), but they also rely on DNA from the nucleus (nDNA). Mitochondrial diseases are caused by mutations in either mitochondrial or nuclear DNA that result in poorly functioning mitochondria. This can cause a variety of symptoms including muscle weakness, seizures, mental retardation, dementia, hearing loss, blindness, strokes, diabetes, and premature death. Most mitochondrial diseases are progressive, and we are unable to cure most of these diseases with currently available treatments.. Research into mitochondrial diseases has been hampered by the low frequency of these disorders and by under-diagnosis by clinicians. This has hindered patient recruitment for research studies and clinical trials. The North American Mitochondrial ...
The National Ecological Observatory Network is a major facility fully funded by the National Science Foundation. Any opinions, findings and conclusions or recommendations expressed in this material do not necessarily reflect the views of the National Science Foundation. ...
The National Ecological Observatory Network is a major facility fully funded by the National Science Foundation. Any opinions, findings and conclusions or recommendations expressed in this material do not necessarily reflect the views of the National Science Foundation. ...
Subscribe or upgrade your current MEED.com package to support your strategic planning with the MENA regions best source of business information. Proceed to our online shop below to find out more about the features in each package. ...
IBBL (Integrated Biobank of Luxembourg) provides biospecimen related services and biobanking infrastructure for applied medical research.
Have you had a blood sample taken for research purposes? If so, youre not alone. Hundreds of pulmonary hypertension (PH) patients in Sheffield are taking part in a world-leading research programme aimed at bringing about new treatments for the disease.. The Pulmonary Hypertension Research Biobank is a growing store of blood products which are being analysed by scientists to better understand the basic biological workings underlying the development of PH.. The collection, held at the University of Sheffield Medical School and the Royal Hallamshire Hospital, includes 900 samples taken from 400 patients since it was set up in 2009. Where the study is unique is that it gathers samples from patients from before their diagnosis and over the longer-term as they undergo therapies.. Dr Allan Lawrie, who leads the talented team behind the research, believes it will lead to breakthroughs in treatment in the future as tools the scientists use for analysis become ever more sophisticated.. The Biobank was ...
A national repository of biological samples from traumatic brain injury (TBIs) patients at the University of Pittsburgh Department of Neurological Surgery. This biorepository supports the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study, a multi-center initiative funded by the National Institutes of Health (NIH).
The biological samples collected in biobanks are a resource with significant research potential, but may also be subject to various ethical and deontological conflicts.. Policies and practices about storage and use of residual newborn screening specimens vary considerably. Several studies show, and denounce, not only significant differences in national policies, but also fragmentations with in federal States (e.g. Australia, United States) [1, 2] and different regional practices within countries (e.g. Italy) [3]. In the European Union, although binding regulations give a common framework to Member States, national regulations, policies and practices vary as regards length of storage, possibility of research use of deidentified samples, parents information sheets, and so on. Moreover, many samples now stored in biobanks were collected years ago, in situations lacking standardization and in contexts where an awareness of the need to meticulously handle information and obtain consent was not yet ...
A new Michigan State University study, published in the Journal of the American Medical Association, indicates that most people are willing to donate just knowing that their contribution is going toward research. But, when specific scenarios are brought into the equation, that willingness changes.. We really wanted to document the concerns people have that may affect their desire to donate, said Tom Tomlinson, director of MSUs Center for Ethics and Humanities. Biobanks are becoming more and more important to health research, so its important to understand these concerns and how transparent these facilities need to be in the research they support.. Tomlinson, who led the study with co-author Raymond De Vries, a bioethics professor at the University of Michigan, surveyed nearly 1,600 people within the United States and found 68 percent were willing to donate using a blanket consent method. This approach gives a biobank one-time permission to use a donation for whatever research they deem ...
Bipolar Disorder Biobank at Mayo Clinic: Collects biological samples to establish and research Bipolar Type I and II disorder causes and treatment.
The Partners Biobank has released a second batch of genotype data to the research community at Partners HealthCare. Genotype data for nearly 9,500 subjects is now available for free. Imputed data will be available in a few weeks for a fee. The Partners Biobank will genotype another ~15,500 subjects over the next two years, releasing data every six months. The subjects are
The LBIH Biobank has been specifically created to provide SMEs and academic researchers with high quality biosamples, data, and analytical services. We house a vast array of biosamples, both cancerous and non-cancerous, and have the ability to collect bespoke samples and data to suit the needs of researchers. We have access to a wide variety of samples types including, but not limited to, frozen tissue, fresh tissue, blood products, urine and FFPE blocks. The LBIH Biobank can further process these into a number of products such as DNA, frozen sections, and cryo-aliquots. In order to offer a one-stop shop for research, we offer additional services such as IHC, next generation sequencing,TMA creation, and project management for studies and projects, to include storage of trial samples. ...
Bipolar Disorder Biobank at Mayo Clinic: Contact the biobank for questions about bipolar disorder or participant and researcher inquires.
Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 years) aged ≥18 years (approximately one-fifth of all Qatari citizens), to follow up these same individuals over the long term to record any subsequent disease, and hence to study the causes and progression of disease, and disease burden, in the Qatari population. Methods: Between the 11th-December-2012 and 20th-February-2014, 1209 participants were recruited into the pilot study of the Qatar Biobank. At recruitment, extensive phenotype information was collected from each participant, including information/measurements of socio-demographic factors, prevalent health conditions, diet, lifestyle, anthropometry, body composition, bone health, cognitive function, grip strength, retinal imaging, total body dual energy X-ray absorptiometry, and measurements of cardiovascular and ...
Ex vivo microscopy is an emerging set of imaging modalities intended to enable histological imaging of whole tissue specimens at the point-of-procedure. Ex vivo microscopy holds much promise for enabling rapid verification of cancer biospecimen quantity and quality at the time of specimen acquisition. Two areas in which such technologies would be extremely helpful to pathologists are in 1) screening of biopsies collected during a biopsy procedure with the aim of providing guidance for collection of additional tissues, and 2) non-destructively assessing and verifying cancer content in biospecimens collected for banking and downstream molecular analysis. In prostate cancer diagnosis, for example, 70-80% of the 1 million biopsies collected for diagnosis each year are ultimately found to be benign on permanent histopathology review. For tissue banking, the major limiting pre- analytical factor for downstream molecular and genetic analysis is the amount of cancerous tissue present in the banked ...
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The Report Biobanking: Developing Smart, Sustainable and Ethically Compliant Biorepositories for the Future provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports. ...
The Biorepository Core serves as a resource to process, track, store, retrieve and prepare biological samples for the research projects within the Center for Molecular Epidemiology.. Critical to successful molecular epidemiologic research are high quality, accessible human biological samples. Automated specimen processing and freezer storage systems are being developed to provide specialized expertise to the proposed projects for the five-year COBRE award, and ultimately produce a sustainable institutional and regional resource Core for Molecular Epidemiology.. Read More ». ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample. Sequence reads were aligned to the hg19/GRCh37 human genome using Tophat v1.4.1 assisted by the GENCODE v19 transcriptome definition. Gene annotations were produced by ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample. Sequence reads were aligned to the hg19/GRCh37 human genome using Tophat v1.4.1 assisted by the GENCODE v19 transcriptome definition. Gene annotations were produced by ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample. Sequence reads were aligned to the hg19/GRCh37 human genome using Tophat v1.4.1 assisted by the GENCODE v19 transcriptome definition. Gene annotations were produced by ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample. Sequence reads were aligned to the hg19/GRCh37 human genome using Tophat v1.4.1 assisted by the GENCODE v19 transcriptome definition. Gene annotations were produced by ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample. Sequence reads were aligned to the hg19/GRCh37 human genome using Tophat v1.4.1 assisted by the GENCODE v19 transcriptome definition. Gene annotations were produced by ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 and HiSeq 2500 platforms to produce 76-bp paired end reads with a coverage goal of 50M (median achieved was ~82M total reads). Sequence reads were aligned to the hg38/GRCh38 human genome using STAR v2.5.3a assisted by the GENCODE 26 transcriptome definition. The ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample.. Sequence reads for this track were quantified to the hg38/GRCh38 human genome using kallisto assisted by the GENCODE v23 transcriptome definition. Read quantification was ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample.. Sequence reads for this track were quantified to the hg38/GRCh38 human genome using kallisto assisted by the GENCODE v23 transcriptome definition. Read quantification was ...
Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample.. Sequence reads for this track were quantified to the hg38/GRCh38 human genome using kallisto assisted by the GENCODE v23 transcriptome definition. Read quantification was ...
When it is used for research it is a biological specimen. Such tissues and organs may be referred to as implant tissue, ... Tissue banks in the US are monitored by the Food and Drug Administration (FDA). The Code of Federal Regulations sets out the ... Biomedical tissue is biological tissue used for organ transplantation and medical research, particularly cancer research. ... Tissue is stored in tissue establishments or tissue banks under cryogenic conditions. Fluids such as blood, blood products and ...
Most biological specimens are extremely radiosensitive, so they must be imaged with low-dose techniques (usefully, the low ... In 2019, cryo-EM structures represented 2.5% of structures deposited in the Protein Data Bank, and this number continues to ... The original rationale for CryoTEM was as a means to fight radiation damage for biological specimens. The amount of radiation ... In addition to allowing vitrified biological samples to be imaged, CryoTEM can also be used to image material specimens that ...
... incorporate a substantial translational research component and emphasise the collection and banking of biological specimens for ...
2009). Nordic biological specimen banks as basis for studies of cancer causes and control - more than 2 million sample donors, ... Furthermore, projects linking immunology and malignancy by studying the genetic and biological basis of malignancies affecting ...
They provide specialized reagents to lower level laboratories and have the ability to bank specimens, perform serotyping, and ... Cieslak, Theodore J. and George W. Christopher (2007), "Medical Management of Potential Biological Casualties: A Stepwise ... to handle specimens safely, and to forward specimens to higher-level labs within the network. These laboratories (more than 100 ... can rule on the presence of the various biological threat agents. They can use BSL-3 practices and can often conduct nucleic ...
... biological specimen banks MeSH N02.278.065.200 - blood banks MeSH N02.278.065.600 - milk banks MeSH N02.278.065.700 - sperm ... banks MeSH N02.278.065.900 - tissue banks MeSH N02.278.065.900.205 - bone banks MeSH N02.278.065.900.400 - eye banks MeSH ...
Biobank Biological database Gene bank Genetic fingerprinting Genomics Genotype ISBER Newsletter Volume No.1, Issue No. 1 " ... The purpose of a biorepository is to maintain biological specimens, and associated information, for future use in research. The ... distribution of biological specimens. (i) Collection or accession is the first operation, whereby samples are recorded as ... Tissue Banks and Biorepositories National Institute of Allergies and Infectious Diseases HIV/AIDS Specimen Repository ...
The zoological collection consists of 1,135,000 animal specimens, including a tissue bank for DNA analysis. It also holds the ... In 1992, the museum began publishing Natura Croatica, a peer-reviewed biological and geological academic journal. The natural ... including over 1.1 million animal specimens. It was founded in 1846 as the "National Museum". The National Museum was later ...
... the fastest available microtechnique to detect gene expression and/or enzyme activity in any biological specimen as well as the ... He also discovered two viruses reported under his name in the world data bank of viruses, the first was named "Peanut Chlorotic ... reported to be the fastest available microtechnique to detect gene expression and/or enzyme activity in any biological specimen ... Wagih have discovered two viruses reported under his name in the world data bank of viruses, the first was named "Peanut ...
The agency is also a United Nations International Drug Control Programme Reference Laboratory for Biological Specimens and ... HSA has been internationally accredited by the AABB (formerly known as the American Association of Blood Banks), and also the ... It runs the [email protected] in Outram, as well as three satellite blood banks - [email protected], [email protected] and ... it secures the national blood supply through its operation of the national blood bank - [email protected]; and it represents the ...
... collects 3D EM maps and associated experimental data determined using electron microscopy of biological specimens. It was ... The EM Data Bank or Electron Microscopy Data Bank (EMDB) ... EM Data Bank also provides the EMsearch search tool and data ... Software tools for molecular microscopy EM Data Bank US and UK Search pages Japan Search page (EM Navigator in PDBj). ... EMDB is an archive for three-dimensional density maps of all types of biological assemblies, including ribosomes, chaperones, ...
Nathan Banks, collecting invertebrates around Barro Colorado and along the railroad in the vicinity of Panama City. Wheeler led ... Donisthorpe and Wheeler also frequently exchanged specimens, leading the latter to first develop the idea that the Formicinae ... Wheeler, W.M. (1910). Ants: Their Structure, Development and Behavior (PDF). Columbia University Biological Series. 9. Columbia ... a six-man venture sent for the dual purpose of procuring specimens - the museum being "weak in Australian animals and...desires ...
About 230 individual specimens have been recorded there. Other species, such as the sperm whale and harbour seal, are also ... The water flow over the banks is weaker and tends have greater variation. The Scotian Shelf contains a canyon called the "Gully ... "Biological Importance of Scotian Shelf Water" (PDF). Grampus.umeoce.maine.edu. Retrieved 27 November 2017. Image Benthic ... The Scotian Shelf is characterized by shallow, offshore banks 25 to 100 metres (82 to 328 ft) under the ocean surface, with ...
... high-resolution digital images of the specimens are included. The ITSD specimen image bank forms the largest single ... All biological material deteriorates over time and these unique digital images will act as a permanent record of the specimens ... Wet specimens are whole animals, organs or body parts that have been preserved in either alcohol or formalin. Specimens of the ... The International Thylacine Specimen Database is a unique and precise database of the largest modern day marsupial carnivore. I ...
The holotype was found on a rocky stream bank in lower montane rainforest at 1,850 m (6,070 ft) above sea level. The site was ... It is unusual in its ghost-like, gray-white coloration, and it was initially thought that the specimen was an albino form of ... Proceedings of the Biological Society of Washington. 109: 744-748. Frost, Darrel R. (2017). "Craugastor phasma (Lips and Savage ... However, the specimen is also morphologically distinct, although some uncertainty regarding the validity of this species ...
Banks, Richard C.; Goodman, S. M.; Lanyon, S. M.; and Schulenberg, T. S. (1993). "Type Specimens and Basic Principles of Avian ... Banks, Richard C. (2011). "Taxonomy of Greater White-fronted Geese", (Aves: Anatidae), Proceedings of the Biological Society of ... Hubbard, John P.; and Banks, Richard C. (1970). "The Types of Taxa of Harold H. Bailey", Proceedings of the Biological Society ... Woolfenden, G. E.; and Banks, Richard C. (2004). "A specimen of the Varied Thrush from Florida", Florida Field Naturalist, 32: ...
Hungary Bank of the National Laboratory for the Genetics of Israeli Populations (NLGIP), Tel-Aviv University Bank for the ... Before the founding of EuroBioBank, researchers typically stored biobank specimens in their own laboratories and used them only ... "EU funded network provides human biological material for research on rare diseases". Times Higher Education. 5 October 2005. ... University of Padua Bank of the Molecular Genetics Laboratory, University of Malta Neuromuscular Tissue Bank of the University ...
Ripe seed was collected in 1991, and sent for storage in the Kew Seed bank. A fuller description is available in the reserve ... Badgeworth SSSI (grid reference SO 911206) is a 3.08-hectare (7.6-acre) biological Site of Special Scientific Interest in ... of a Badgeworth specimen) Guy, C, Haigh, D, Harris, Lucy, Harris, Lyn, Parker, J, Ralphs, I, Tandy, C, (1977 edition edited ... This could be an old seed bank or spread on the feet of animals or birds. Hanbury, F J, (1890), 'Ranunculus ophioglossifolius ...
Baer was interested in the northern part of Russia, and explored Novaya Zemlya in 1837, collecting biological specimens. Other ... erosion occurs mostly on the right banks of rivers, and in the Southern Hemisphere on the left banks. In its more thorough ... Before the Estonian conversion to the euro, the 2-kroon bank note bore his portrait. Baer Island in the Kara Sea was named ... He was a pioneer in studying biological time - the perception of time in different organisms. ...
Returned J. Banks, Middlesex Yeomanry; W.B. Caverhill, Berwick Yeomanry; T. Custance, Strathcona's Horse; Lieut. D.H. Greig, ... The biological laboratory occupied the tower. The room furnished with microscopes and other apparatus associated with Botanical ... In addition to a section devoted to soils and specimens of rocks and fossils the museum housed a variety of animal curiosities ... There was a collection of natural history specimens displayed in each corner of the hall. These included a magnificent Bengal ...
... by Benedict Wells tells the story of a fictitious child produced by the sperm bank, who searches for his biological father. ... intending to donate specimens, only to leave after Sheldon suffers a moral crisis over committing "genetic fraud" by donating ... ISBN 1-4000-6124-5 Series of Slate.com articles on the sperm bank Guardian article on Graham and his bank's history BBC Article ... a businessman from Ohio who had shown interest in the bank. At the time of Graham's death, the bank claimed to have produced ...
Alexander Kouzminov Biological Espionage: Special Operations of the Soviet and Russian Foreign Intelligence Services in the ... In the 1980s and 1990s, specimens of deadly bacteria and viruses stolen from Western laboratories were delivered by Aeroflot to ... All proceeds from ticket sales were distributed to 352 foreign bank accounts that could not be controlled by the Aeroflot ... Denial and deception Dummy corporation False flag FBI GONGO Mafia Media transparency Money laundering Money loop Offshore bank ...
Some specimens contain only 6 whorls instead of 7 as in the holotype. The upper whorls are smooth, then follows the body whorl ... Bank R, Neubert E, Moretzsohn F, Faber M, Houart R, Picton B, Garcia-Alvarez O (eds.). "Guildfordia yoka Jousseaume, 1899". ... Publications of the Seto Marine Biological Laboratory. 3 (2): 170-171. doi:10.5134/174471. hdl:2433/174471; Pl. 9, Figs. 5, 6. ... Some specimens lack the rose-coloured line round the umbilical callosity. The aperture is oval, thick, with the nucleus in the ...
Biological dispersal then takes place as pieces break off and float downstream. Blooming occurs in mid-June through mid-July, ... One population was located after a biologist found a specimen used as a garnish on his plate at a restaurant. The plant has ... It grows on lakesides and stream banks in wet, saturated soils or in very shallow water. It requires cold, clear flowing water ...
The museum is located on the banks of Karanji Lake, with the Chamundi Hills visible in the background. It is now a landmark in ... Biological Diversity has multiple sections. The first section has a special emphasis on the western ghats. It exhibits the ... Children can handle, examine and study specimens in the discovery room. A mini theater, a sound booth are also present to keep ...
... though specimens had been discovered on Raoul Island in the Kermadec Islands chain since the 1970s), and the first specimen in ... Banks, N. (1913) "On a collection of neuropteroid insects from the Philippine Islands"., Proceedings of the Entomological ... Wise, K.A.J. (1995). "RECORDS CONCERNING BIOLOGICAL CONTROL OF INSECT PESTS BY NEUROPTEROIDEA (INSECTA) IN NEW ZEALAND". ... Specimens can be identified by a green pterostigma present in the hind wings that is not present in Chrysopidae of a similar ...
This was in the collection of Joseph Banks at Latham's time, but later became lost. During Cook's visit, the bird was observed ... John Latham figured the bird as the "Barred Phalarope" in his General Synopsis of Birds, based on a Kiritimati specimen ... Biological Conservation. 103 (2): 139. doi:10.1016/S0006-3207(01)00112-4. Latham, John (1785): ["Barred Phalarope"]: In: A ... The Tuamotu birds only came to the attention of science during the US Exploring Expedition, which collected five specimens in ...
"Notes from the San Diego biological laboratory. The fishes of Cortez banks; additions to the fauna of San Diego; fishes of ... with notes on the specimens contained in the Museum of Comparative Zoology, at Cambridge, Massachusetts," as well as " ... After their return to California in 1889, the Eigenmanns established a biological station in San Diego and continued their ... 28-56 "South American Nematognathi," American Naturalist (1888) 23: 647-49 "Contributions from the San Diego biological ...
Sonnerat collected bird and plant specimens on his travels. He was the first person to give a scientific description of the ... Sonnerat returned to Europe in 1813, meeting Joseph Banks in London and returned to Paris in 1814 where he died. ... "Sonnerat, Pierre (1745-1814)". Cite journal requires ,journal= (help) Isaak, M. (2008). Curiosities of Biological Nomenclature ...
The type specimens were collected by William Baxter in the mountains near King George Sound in 1829. In 1891, Otto Kuntze, in ... Banksia baxteri is serotinous, that is, it has an aerial seed bank in its canopy in the form of the follicles of the old flower ... Canberra: Australian Biological Resources Study, Canberra. p. 200. Retrieved 2 April 2020. George, Alex S. (1981). "The genus ...
In 1990, the Cancha de Bochas Member produced more Herrerasaurus specimens, also from its Carnian beds.[65] Specimen PVSJ 53, ... Series B, Biological Sciences. 309 (1139): 395-460. Bibcode:1985RSPTB.309..395C. doi:10.1098/rstb.1985.0092.. ... These plants formed lowland forests along the banks of rivers.[4] Herrerasaurus remains appear to have been the most common ... Scale diagram showing the holotype specimen (red) and the largest known specimen (gray), compared in size with a human. ...
When his ship Union foundered near the coast of Connecticut, he lost all his books (50 boxes) and all his specimens (including ... Rafinesque was one of the first to use the term "evolution" in the context of biological speciation.[30] ... 1837: Safe Banking. *1837: Notes to Thomas Wright's Original Theory, or New Hypothesis of the Universe. ... Örstan, Aydin (2014). "Two early nineteenth-century uses of the term "evolution" to denote biological speciation". Archives of ...
All collecting of biological specimens is subject to proper collecting and export permits; frequently, specimens are returned ... Banks, RC; Clench, MH; Barlow JC (1973). "Bird collections in the United States and Canada". Auk. 90: 136-170.. ... In today's museum, only a small fraction of the specimens and artifacts are publicly displayed. The vast majority of specimens ... shipping over 42,000 specimens to researchers, per its Annual Report.[83] The collection specimens are an important cornerstone ...
... with larger specimens found to the north of the opossum's range and smaller specimens in the tropics. They measure 13-37 inches ... "Proceedings of the Royal Society B: Biological Sciences. 275 (1637): 923-928. doi:10.1098/rspb.2007.1645. PMC 2599941. PMID ... an extinct megafaunal rodent from the Anguilla Bank, West Indies: Estimates and implications". American Museum Novitates. New ... The largest specimen yet found is estimated to weigh up to 1,600 kg (3,500 lb) and stood up to 3.29 m (10 ft 10 in) tall on the ...
"Philosophical Transactions of the Royal Society B: Biological Sciences. 361 (1465): 23-43. doi:10.1098/rstb.2005.1736. PMC ... All other parrots and cockatoos nest in cavities, either tree hollows or cavities dug into cliffs, banks, or the ground. The ... Fossil dentary specimen UCMP 143274 restored as a parrot (left) or an oviraptorosaur ... "The Institute for Biological Invasions. Archived from the original on 2007-07-01.. ...
EM Data Bank (EM Data Bank) Frank, Joachim (2006). Three-dimensional electron microscopy of macromolecular assemblies: ... An area of the specimen is imaged at both zero and at high angle (~60-70 degrees) tilts, or in the case of the related method ... Biological samples, and especially samples embedded in thin vitreous ice, are highly radiation sensitive, thus only low ... The specimen stage of the microscope can be tilted (typically along a single axis), allowing the single particle technique ...
Biological Conservation, 143(3), 710-721. *^ a b c d e Love, J. A. (1988). The reintroduction of the white-tailed sea eagle to ... Prey specimens can often include fish, birds and, mostly in a secondary capacity, mammals.[3][9] White-tailed eagles are ... on sand banks or among reed beds.[32] Showing their adaptability, one pair even nested on a buoy on a Norwegian shipping route. ... Biological Conservation, 4(5), 373-377. *^ Kalisńska, E., Salicki, W., & Jackowski, A. (2006). Six Trace Metals in White-Tailed ...
"Proceedings of the Royal Society B: Biological Sciences. 283 (1841): 20161762. doi:10.1098/rspb.2016.1762. ISSN 0962-8452. PMC ... Surveys and specimens of brown rat populations throughout the world have shown this species is often associated with outbreaks ... In the absence of humans, brown rats prefer damp environments, such as river banks.[56] However, the great majority are now ... Some colonies along the banks of the Po River in Italy will dive for mollusks,[29][30] a practice demonstrating social learning ...
Proceedings of the Biological Society of Washington. 116 (1): 29-37.. *^ a b V.J. Syverson (2007). "Evolutionary Patterns in ... Banks, Alicia (June 16, 2014) "Condor spotted in San Mateo County is first in 110 years" Los Angeles Times ... Archibald Menzies collected the type specimen "from the coast of California" during the Vancouver expedition.[3] It was ...
... is the use of DNA profiles to determine whether an individual is the biological parent of another ... To satisfy the chain-of-custody legal requirements, all tested parties have to be properly identified and their specimens ... formerly American Association of Blood Banks). Similarly, in Canada, the lab needs to be accredited by the SCC. ... Current advances in genetic testing have led to the ability to determine who the biological father is while the woman is still ...
Left: A dissected male specimen of Onykia ingens, showing a non-erect penis (the white tubular structure located below most of ... Journal of the Marine Biological Association of the UK 83: 523-534. ... Bank R, Neubert E, Moretzsohn F, Faber M, Houart R, Picton B, Garcia-Alvarez O (eds.). "Onykia ingens (E. A. Smith, 1881)". ... Right: A specimen of the same species exhibiting elongation of the penis to 67 cm in length ...
Journal of the Marine Biological Association of the United Kingdom. 79 (5): 871-880. doi:10.1017/S0025315498001039.. ... One living specimen was found at Clachan Sound, and earlier records showed findings of gastropod shells.[138] ... "Shetland Bat Records" Archived 22 November 2008 at the Wayback Machine Shetland Biological Records Centre. Retrieved 10 August ... a member of the biological order artiodactyla or "even-toed ungulates", is still 400,000 strong, although its existence in the ...
Amongst his students was Felix Plater, who became a professor of medicine, and accumulated many plant specimens, but also ... Joseph Banks. *Johan Christian Fabricius. *James Hutton. *John Ray (Historia Plantarum). *Comte de Buffon (Histoire Naturelle) ... Marine Biological Laboratory. *Max Planck Society. *Pasteur Institute. *Rockefeller University. *Rothamsted Experimental ... He returned the favor - and kept helpful specimens coming - by naming plants after correspondents and friends.[33] ...
... from a specimen given to him by Sir Joseph Banks)[16] and following the rules of priority of nomenclature, it was later ... "Philosophical Transactions: Biological Sciences. 353 (1372): 1081-91. doi:10.1098/rstb.1998.0267. PMC 1692311. PMID 9720106.. ... "Philosophical Transactions: Biological Sciences. 353 (1372): 1115-25. doi:10.1098/rstb.1998.0270. PMC 1692310. PMID 9720109.. ... "Philosophical Transactions: Biological Sciences. 353 (1372): 1221-37. doi:10.1098/rstb.1998.0278. PMC 1692306. PMID 9720117.. ...
... biological specimens, notes, plans, and drawings collected by the members of the commission. Menou refused to hand them over, ... of Egyptian rock samples showed a close resemblance to rock from a small granodiorite quarry at Gebel Tingar on the west bank ... who finally agreed that items such as natural history specimens would be considered the scholars' private property.[41][43] ...
A 20m specimen is reported from a Soviet whaling fleet near the Kuril Islands in 1950.[35][36] There is disagreement on the ... "Proceedings of the Royal Society B: Biological Sciences. 277 (1699): 3527-3531. doi:10.1098/rspb.2010.0863. PMC 2982231. PMID ... American sperm whaling soon spread from the east coast of the American colonies to the Gulf Stream, the Grand Banks, West ... Journal of the Marine Biological Association of the United Kingdom. 58 (1): 1-17. doi:10.1017/S0025315400024371. Archived from ...
1982), The Growth of Biological Thought: Diversity, Evolution, and Inheritance. The Belknap Press of Harvard University Press: ... Many civil servants took an interest in their new surroundings, sending specimens back to museums in the Britain. (See also: ... Joseph Banks. *Johan Christian Fabricius. *James Hutton. *John Ray (Historia Plantarum). *Comte de Buffon (Histoire Naturelle) ... Studies in History and Philosophy of Biological and Biomedical Sciences, 39 (3): 326-337, doi:10.1016/j.shpsc.2008.06.006, PMID ...
"Proceedings of the Royal Society B: Biological Sciences. 285 (1881): 20181071. doi:10.1098/rspb.2018.1071. PMC 6030529. PMID ... Whitaker, R.; Members of the Gharial Multi-Task Force; Madras Crocodile Bank (2007). "The Gharial: Going Extinct Again" (PDF). ... John Edward Gray reviewed zoological specimens in the collection of the Natural History Museum, London. He also considered the ... As of 1999, gharials were also kept in the Madras Crocodile Bank Trust, Mysore Zoo, Jaipur Zoo and Kukrail Gharial ...
Mitchell, Bruce D.; Banks, Peter B. (2005). "Do wild dogs exclude foxes? Evidence for competition from dietary and spatial ... as well as specimens that remained wild and shy. He also reported about dingoes that were aggressive and completely ... Biological Conservation. 103 (3): 283-301. doi:10.1016/S0006-3207(01)00139-2.. ... a study was conducted on pre-20th century dingo specimens that are unlikely to have been influenced by later hybridisation. The ...
"Taiga Biological Station: FAQ". Taiga Biological Station. March 23, 2010. Retrieved 2011-02-21.. ... Trees have a theoretical maximum height of 130 m (430 ft),[164] but the tallest known specimen on earth is believed to be a ... Crook, M. J.; Ennos, A. R.; Banks, J. R. (1997). "The function of buttress roots: a comparative study of the anchorage systems ... Living trees have been used in bonsai and in tree shaping, and both living and dead specimens have been sculpted into sometimes ...
In 1830, Cuvier and Geoffroy engaged in a famous debate, which is said to exemplify the two major deviations in biological ... Influence on Cuvier's theory of extinction was his collection of specimens from the New World, many of them obtained from ... Joseph Banks. *Johan Christian Fabricius. *James Hutton. *John Ray (Historia Plantarum). *Comte de Buffon (Histoire Naturelle) ... anatomy before publishing his analyses of the fossil specimens.[59] The department of palaeontology dealing with the Mammalia ...
The infections from both tyrannosaurs were received by being bitten during a fight, like the Herrerasaurus specimen.[72] ... Vaisberg, Horneck G.; Eschweiler, U.; Reitz, G.; Wehner, J.; Willimek, R.; Strauch, K. (1995). "Biological responses to space: ... These diseases are fundamentally biological poisonings by relatively small numbers of infectious bacteria that produce ...
A range of tree species with individual specimens of varying sizes and ages, and a range of features such as streams, level ... It is characterized by both physical and biological features. A species's habitat is those places where it can find food, ... sand banks, mudflats, brackish lagoons, sandy and pebbly beaches, and seagrass beds, all supporting their own flora and fauna. ...
... the island in January 1973 where both of these were later made to be specimen where smaller specimen became the only specimen ( ... "Proceedings of the Royal Society of London B: Biological Sciences. 279 (1737): 2363-2368. doi:10.1098/rspb.2011.2429. PMC ... and Great Chagos Bank,[168] or even crossing the line on occasions where E. australis have been known to reach Kiribati,[176] ... On October 4, 2000, the Center for Biological Diversity (CBD) petitioned NMFS to designate the southeast Bering Sea shelf from ...
Enriching and preserving the gene bank collection to make potatoes adaptive to diverse environmental conditions is seen as a ... Ames, M.; Spooner, D.M. (February 2008). "DNA from herbarium specimens settles a controversy about origins of the European ... GMO Safety: Genetic engineering on potatoes Biological safety research projects and results ...
... the corpse of a lioness was found on the banks of the Karun River in Iran's Khuzestan Province.[54][55] ... other naturalists and zoologists also described lion specimens from other parts of Asia that used to be considered synonyms of ... Biological Conservation. 144 (5): 1753-1757. doi:10.1016/j.biocon.2011.02.009.. ... there is evidence of lion predation on mugger crocodiles on the banks of the Kamleshwar Dam (built on Hiran River) during dry, ...
In the Spring of that year he drew figures for the book, synthesising his views of specimens in Jena and published pictures to ... "pioneer in biological state thinking".[75] This opinion was also shared by the scholarly journal, Der Biologie, which ... Joseph Banks. *Johan Christian Fabricius. *James Hutton. *John Ray (Historia Plantarum). *Comte de Buffon (Histoire Naturelle) ... Though he made no suggestion that embryo illustrations should be directly based on specimens, to him the subject demanded the ...
With the discovery of new species and Sir Joseph Banks' original introduction of specimens to Europe in 1789, interest in ... "Saudi Journal of Biological Sciences. 18 (1): 7-15. doi:10.1016/j.sjbs.2010.07.003. ISSN 1319-562X. PMC 3730927. PMID 23961098. ... Hewitt-Cooper, N (2012). "A case of bird capture by a cultivated specimen of the hybrid Nepenthes × mixta". Carnivorous Plant ... Beaver, R.A. (1979). "Biological studies of the fauna of pitcher plants Nepenthes in west Malaysia". Annales de la Société ...
The procedure is not often encouraged for young single childless men as their chances for biological parenthood are thereby ... Most physicians and surgeons who perform vasectomies recommend one (sometimes two) postprocedural semen specimens to verify a ... The cost of cryo-preservation (sperm banking) may also be substantially less than alternative vaso-vasectomy procedures, ... sperm granulomas to be formed by the body to contain and absorb the sperm which the body will treat as a foreign biological ...
Around 80% of the global soybean crop is used to feed livestock.[47] According to the World Bank, animal agriculture is ... Agricultural and Biological Publications. New York: McGraw-Hill Book Company. OCLC 252589754 - via google.com.. ... charred soybean specimens. [78] However, the oldest preserved soybeans resembling modern varieties in size and shape were found ... Soybean protein isolate has a biological value of 74, whole soybeans 96, soybean milk 91, and eggs 97.[24] ...
Biological Specimen Bank. This facility houses specimens collected as part of the departments epidemiological studies and ... The EEH specimen bank currently houses about 700,000 samples from approximately 20,000 participants. ... The specimens are stored either in -80°C freezers and in cryogenic containers, or immersed in liquid nitrogen (-196 °C). A ... biological and radiological agents. We do this by improving knowledge and understanding of the physiological stresses that ...
Find marine biological articles on Environmental XPRT, the worlds largest environmental industry marketplace and information ... Marine specimen banking: archive and pollution control for the 21st century The oceans have in the past been extensively used ... marine biological Articles. Related terms for "marine biological ": marine biological sampling equipment articles , marine ... Trace metal status in marine biological samples: a review The literature on trace metal status in marine biological samples is ...
Monitoring Environmental Materials and Specimen Banking : Proceedings of the International Workshop, Berlin (West), 23-28 ... State-of-the-art of biological specimen banking in the Federal Republic of Germany.- Ecological action of mercury by-products ... Use of oysters and related molluscs as biological monitors of synthetic organic pollutants.- Specimen banking marine organisms ... Experiences in monitoring and banking human biological specimen.- Organohalogenated compounds in plants and soil.- Terrestrial ...
Owner name: SILICON VALLEY BANK, GEORGIA. Free format text: SECURITY INTEREST;ASSIGNOR:CELL ANALYSIS SYSTEMS, INC.;REEL/FRAME: ... Optical specimen analysis system and method. US5787189 *. Jun 20, 1996. Jul 28, 1998. Neopath, Inc.. Biological analysis system ... Biological specimen analysis system processing integrity checking apparatus. US5905808 *. Aug 19, 1998. May 18, 1999. Ortho ... Biological specimen analysis system processing integrity checking apparatus. WO2004021260A1 *. Aug 22, 2003. Mar 11, 2004. ...
Biological Specimen Banks / standards* * Blood* * Clinical Laboratory Techniques * Humans * Metabolome * Metabolomics / methods ...
Biological specimen banks. *informed consent. *research subjects. *confidentiality. *trust. Introduction. Biorepositories are ... The application of molecular technologies to collections of human biological specimens represents an unparalleled opportunity ... Efforts to compile health information and collect biological specimens from large populations are already under way in the ... As one stated: "Its kind of like a blood bank except that its not for people who need blood to live, its for people who need ...
Biological Markers Blood Banks. Blood Chemical Analysis. Blood Circulation. Blood Specimen Collection ... You are here: Home / Research / Tools & Resources / Biomedical Specimens and Population Research / Literature ... Biological Sciences Because its focus is on medicine the best tool to identify population-related biomarker research articles ... Biological Psychology Biomarkers Cancer Epidemiology, Biomarkers & Prevention (CEBP) Critical Reviews in Oncology/Hematology ...
Biological Specimen Banks / ethics * Biological Specimen Banks / legislation & jurisprudence * Biological Specimen Banks / ...
... has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens ... The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved ... AIDS and Cancer Specimen Bank (ACSB). The safety and scientific validity of this study is the responsibility of the study ... These specimens will be banked and linked to a clinical data set so that experimental results obtained by analysis of specific ...
... has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens ... AIDS and Cancer Specimen Bank (ACSB). Brief Summary The purpose of this study is to obtain clinical specimens from pathologists ... The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved ... AIDS and Cancer Specimen Bank (ACSB). The safety and scientific validity of this study is the responsibility of the study ...
Nørgaard-Pedersen B, Simonsen H. Biological specimen banks in neonatal screening. Acta Paediatr Suppl. 1999;88(432):106-109. ... along with a matched sample of control specimens. Ideally, specimens should be retrieved for all children who died in infancy ... linked 32 specimens positive for CH by thyroid stimulating hormone (TSH) screening to childrens records, and 31 of these ... If the primary endpoint for a disorder is mortality, a less expensive alternative is to link stored blood spot specimens with ...
The invasive sea squirt that federal and university researchers discovered on Georges Bank a year ago is flourishing in U.S. ... Width of specimen shown is 9 inches. Collectors: Page Valentine, Jeremy Collie, and Robert Reid. Photo credit: Dann Blackwood, ... biological, energy, and mineral resources; and enhance and protect our quality of life. To receive USGS news releases go to: ... Northern Georges Bank (41 deg 54.429 min N lat, 67 deg 27.146 min W lon). Water depth 59 m (194 ft). November 2004. Width of ...
... and other biological samples and specimens; cell banking methods, apparatus, and services; pending and planned patent ... 7.3 Employee further agrees to deliver to Opexa at the termination of Employees employment all biological materials ... Shanghai Institute for Biological Science, China Academy of Science of the Peoples Republic of China. In exchange for a ... biological materials, and other developments (all of the above are collectively referred to as the "Developments") conceived, ...
A COG Study for Collecting and Banking Ewing Sarcoma Specimens. Official Title: A COG Study for Collecting and Banking Ewing ... Research InnovationClinical Studies Collecting and Storing Biological Samples From Patients With Ewing Sarcoma ... Sarcoma Specimens This research study is collecting and storing samples of tumor tissue, bone marrow, and blood from patients ...
Acquisition and Reception of Primary Tissues, Cells, or Other Biological Specimens. Pages 17-27 ... Quality Assurance in Stem Cell Banking: Emphasis on Embryonic and Induced Pluripotent Stem Cell Banking ... Stem Cell Banking: Concepts and Protocols aims to contribute to the development of this field by providing information that is ... Cutting-edge and thorough, Stem Cell Banking: Concepts and Protocols is a valuable resource for stem cell scientists and ...
When it is used for research it is a biological specimen. Such tissues and organs may be referred to as implant tissue, ... Tissue banks in the US are monitored by the Food and Drug Administration (FDA). The Code of Federal Regulations sets out the ... Biomedical tissue is biological tissue used for organ transplantation and medical research, particularly cancer research. ... Tissue is stored in tissue establishments or tissue banks under cryogenic conditions. Fluids such as blood, blood products and ...
Keywords: biological specimen banks; ethics, research; informed consent; health research policy; incidental findings; Brazil. ... Cell Tissue Bank. 2007;8(4):287-95. 16. McNelly E, Cambon-Thomsen A. Twenty-five recommendations on the ethical, legal, and ... f) Steps will be taken to ensure anonymity in any form of disclosure of information derived from the use of his/her biological ... a) Biological human samples are sent to other countries for experiments that cannot be performed locally. ...
Categories: Biological Specimen Banks Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Biological Specimen Banks Carcinoma, Squamous Cell Case-Control Studies Continental Population Groups DNA-Binding Proteins ... providing a comprehensive reference for phylogenetic classification of HPV18 sublineages for epidemiological and biological ...
There are two types of national research infrastructure: National Research Facilities and National Biological Collections. ... NRCAs six biological collections contain more than 15 million specimens, representing a 240-year time-series of data on the ... The oldest specimen in the Australian National Herbarium was collected in 1770 by Joseph Banks. ... The NRCA contain many representations of PNG biological specimens, resulting from land-use surveys in PNG during the 1950s, ...
Department of Social & Preventive Medicine (SPM) Biological Specimen Bank. The facility houses specimens collected as part of ... which in conjunction with the specimen bank at RPCI and the future biobank in the CTRC provides a novel resource for ... Data Bank and BioRepository (DBBR). Collects and provides de-identified biospecimens and associated epidemiological and ... Provides human specimens and laboratory services for basic and translational research to further the understanding of the ...
Biological Specimen Banks. *Databases, Factual. *Humans. *Sensitivity and Specificity. Related in: MedlinePlus ...
Human tissues were retrieved from the bank of biological specimens of the Perinatology Research Branch. Fresh-frozen tissues ... Biological Sciences. *. Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS ...
The collected biological specimens are either banked or sent to laboratories for processing. Physical examination takes place ... methods and protocols with a private-sector contractor that could go into jails and prisons and collect biological specimens. ...
Biological specimens archived in the European Bronchial Tissue Bank. Specimen type. n. ... EBTB: European Bronchial Tissue Bank; DTT: dithiothreitol; HE: haematoxylin and eosin; PAP: papanicolaou test. ... EBTB: European Bronchial Tissue Bank; WBC: white blood cells; EDTA: ethylenediamine tetraacetic acid. ... SPLC: second primary lung cancer; CT: computed tomography; EBTB: European Bronchial Tissue Bank. ...
Repository is a storage bank of crew biological specimens collected over extended periods of time. Repository supports ...
Biological specimen banks Biomedical research Clinical medicine Clinical trial Clinical registries This is a preview of ...
Biological Measures for Prognosing and Monitoring of Persistent Concussive Symptoms in Early and Middle Adolescents: Center ... Biological Samples. All biological specimens are required to be banked at the NINDS BioSEND Biomarkers Repository. When ... The biological mechanism of action for each biological measurement is not required to be known, although it may be advantageous ... Authentication of Key Biological and/or Chemical Resources. For projects involving key biological and/or chemical resources, ...
Biological Measures for Prognosing and Monitoring of Persistent Concussive Symptoms in Early and Middle Adolescents: Center ... Biological Samples. All biological specimens are expected to be banked at the NINDS BioSEND Biomarkers Repository. When ... Authentication of Key Biological and/or Chemical Resources. For projects involving key biological and/or chemical resources, ... interim analysis for biological measures including alternative strategies, and for the selection of biological measures that ...
  • The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non- AIDS associated malignancies. (clinicaltrials.gov)
  • The new National ALS Biorepository will collect, process, store, and disseminate a variety of biological specimens such as blood, urine, and tissue from a sample of persons with ALS enrolled in the National ALS Registry who agree to take part in the Biorepository. (cdc.gov)
  • Testing is performed on a variety of biological specimens using manual or automated techniques and require a broad exercise of independent judgment and responsibility with minimal technical supervision. (healthecareers.com)
  • We gathered input on a consent template developed for the Duke Biorepository from individuals representative of those who might one day consider contributing specimens. (aacrjournals.org)
  • There is a conceptual divergence in the literature with regard to the infrastructure and practices regarding the collection of human biological material for research, wherein the term "biobank" has been used interchangeably with "biorepository. (scielosp.org)
  • Projects of the NIST Biorepository are specifically designed to cryogenically store specimens over long periods of time (50-100 years). (nist.gov)
  • The National ALS Biorepository is an exciting new component of the National ALS Registry that will increase the number of biological samples from persons with ALS available for research. (cdc.gov)
  • The National ALS Biorepository is different from other biorepositories because it collects specimens from a geographically representative sample of people with ALS that is not tied to a specific clinic or location. (cdc.gov)
  • As part of our commitment to promoting reproducibility in the life sciences, ATCC provides researchers with cGMP-compliant biorepository services that enable the secure and reliable storage and management of your precious biological materials. (atcc.org)
  • A DNA repository, containing two types of specimens: whole blood and sputum pellets and immortalized cells, is being developed with approximately 50% of anticipated samples collected to date. (nih.gov)
  • Population-based bio banking of blood from healthy individuals in large epidemiological cohorts and of biological fluids and tissue specimens both in healthy as well as in diseased subjects constitutes the "core" of biobanks. (omicsonline.org)
  • The personal data derived from the registry, correlated with biological information derived from the tissue specimens will allow for future investigative studies of pancreatic cancer etiology and tumor biology. (columbiasurgery.org)
  • The SWAN Repository contains blood and urine specimens, collected at each study participant's annual visit. (nih.gov)
  • In 2014, participants who completed the initial 24-hour urine collection were also asked to collect another two urine specimens: a void in the evening and the first void the following morning. (cdc.gov)
  • This article outlines and discusses Brazil's new regulations on the use of human biological materials for research, specifically, Resolution CNS 441/11, enacted by the National Health Council of Brazil in May 2011, and the National Guidelines for Biorepositories and Biobanks (Ordinance No. 2201) published by the Ministry of Health in September 2011. (scielosp.org)
  • Population-based biobanks usually explore germline biological traits, whereas biobanks of specimens from diseased subjects aimed to investigate somatic alterations associated to different types of diseases. (omicsonline.org)
  • 3) Disease-oriented biobanks (usually tumor banks) aimed to identify disease biomarkers in a collections of samples and their derivates (DNA/RNA/proteins), usually associated to clinical data and / or clinical trials. (omicsonline.org)
  • We are currently seeing unprecedented proliferation in the number and capacity of these biobanks, whether in terms of storage duration, quantities of banked specimens, bank sites or related financial issues. (ladydavis.ca)
  • Data banks and biobanks are a valuable resource providi ng evidence that far exceeds the anecdotal knowledge culled from limited quantities of information or biological specimens. (ladydavis.ca)
  • The National Cancer Institute has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens available for scientists studying malignancies associated with HIV disease. (clinicaltrials.gov)
  • Results of these analyses are made available to federal and provincial wildlife agencies, and tissues from carcasses and eggs are stored in the CWS Specimen Bank (a national archive of biological specimens) for future research. (bsc-eoc.org)
  • The authors examine the differences between sample collections for single studies and large-scale collections for multiple studies (e.g., the National Tumor Bank at the Brazilian National Cancer Institute and the A. C. Camargo Hospital Biobank). (scielosp.org)
  • Hence, we sought to outline a step-by-step protocol detailing how we established our HS biobank to facilitate the formation of other HS tissue banks. (nature.com)
  • The purpose of this manuscript is to present a detailed, step-by-step protocol for collecting HS specimens and building an HS biobank. (nature.com)
  • Strict patient confidentiality protection guidelines are in place for all specimens in the ACSB. (clinicaltrials.gov)
  • Efforts to compile health information and collect biological specimens from large populations are already under way in the United States and around the world ( 2 ), with the ultimate goal of unlocking the genomic basis of disease and ushering in an era of personalized medicine ( 3 ). (aacrjournals.org)
  • A random half of those who completed the initial 24-hour urine collection were recruited to collect a second 24-hour urine specimen 3 to 10 days later. (cdc.gov)
  • After completing the 24-hour urine collection, participants were instructed to collect these two full voids at home in separate specimen cups and mail them back to the contract laboratory. (cdc.gov)
  • Female and male participants aged 14-59 were asked to self-collect a vaginal or penile specimen using a sterile swab. (cdc.gov)
  • To accomplish this goal, the NCS planned to collect and bank serial environmental samples and biological specimens for each mother-child dyad to allow later measurement of exposures and genetic and epigenetic analyses. (aappublications.org)
  • The ROV robotic arms were also used to collect biological specimens for NUI Galway's SFI funded project 'Exploiting and Conserving Deep Sea Genetic Resources' and will also give new information on where sensitive species are found to help research at University of Plymouth's Deep Sea Conservation Unit to predict where high value ecological areas might be found offshore Ireland and the wider North East Atlantic. (marine.ie)
  • The objective of this protocol is to obtain clinical specimens from potential participants in clinical trials conducted by the AIDS Malignancies Consortium, and from other patients with and without HIV infection, who have AIDS-Associated malignancies. (clinicaltrials.gov)
  • The EEH specimen bank currently houses about 700,000 samples from approximately 20,000 participants. (buffalo.edu)
  • Still, questions remain: how can the collection, storage, and future research use of specimens and data be described so that prospective participants can make informed decisions? (aacrjournals.org)
  • He was also one of the participants in the RAND report on Tissue Banking. (upmc.edu)
  • NHANES collects biological specimens (biospecimens) for laboratory analysis to provide detailed information about participants' health and nutritional status. (cdc.gov)
  • Participants aged 6 and older were asked to provide a full void of urine in the MEC using a specimen cup. (cdc.gov)
  • The examining dentist instructed participants aged 14-69 to gargle and swish with mouthwash for 30 seconds and then spit into a specimen container. (cdc.gov)
  • ATSDR conducted a study from 2011-2015 to pilot methods for collecting and banking biological specimens from participants in ATSDR's Registry. (cdc.gov)
  • The pilot study recruited a nationally representative sample of patients enrolled in Registry and included two specimen collection components: biological specimens from living participants (in-home) and postmortem specimens. (cdc.gov)
  • At PPMI's 33 clinical sites in 11 countries, 1,400 participants have contributed data and biosamples to the most robust Parkinson's database and specimen bank ever created. (michaeljfox.org)
  • The specimens are stored either in -80°C freezers and in cryogenic containers, or immersed in liquid nitrogen (-196 °C). A complex, secure computerized mapping system tracks the specimens and a sophisticated back-up system maintains integrity. (buffalo.edu)
  • He was referring to the blood samples banked in the BHP freezers. (harvard.edu)
  • A visualization tool gives users a hierarchical view of specimen flow, actually showing the freezers and the boxes and plates within it, to find samples, assess storage utilization, and identify available freezer space for optimizing storage. (labvantage.com)
  • He argues that they both have excellent genetics that would be "wasted" if they do not jump at what could be their only chance to have biological children. (slate.com)
  • The first person accredited with making a cell bank for widespread use was Kral, a Czechoslovakian scientist who created his cell bank collection in the late 1890s. (wikipedia.org)
  • In January 2003, the UK Stem Cell Bank was established to serve as a central unit for specimen collection and human testing. (wikipedia.org)
  • Equipping researchers with carefully detailed processes for collection of HS specimens would accelerate the accumulation of well-organized human biological material. (nature.com)
  • Figure 1 provides an overview to our approach to specimen collection for translational studies in HS, emphasizing the role of collecting clinical phenotypic data for correlation with basic laboratory findings. (nature.com)
  • Provia Laboratories, LLC ( http://www.provialabs.com ) is a health services company specializing in high quality biobanking (the collection, transport, processing, and cryogenic storage of biological specimens). (prweb.com)
  • COG is a NIH/National Cancer Institute cooperative research coalition that conducts pediatric cancer clinical and biological trials, including specimen collection and statistical analyses. (bio-medicine.org)
  • He oversees the tissue and biological specimen collection at the 3 flagship hospitals of the University of Pittsburgh Health Systems. (upmc.edu)
  • Collection procedures varied based on the specimen types. (cdc.gov)
  • Descriptive information such as date and time of collection, study identifier, and specimen type is stored in an electronic inventory system that links to non-confidential demographics such as the age and sex of the participant. (harvard.edu)
  • The literature on trace metal status in marine biological samples is reviewed, taking into account the importance of the subject. (environmental-expert.com)
  • Head of the project is obliged to mention the origin of the samples (Environmental Specimen Bank, Swedish Museum of Natural History) in publications and send a sample of the publication/report, without no expense, to Swedish Museum of Natural History, Sara Danielsson (see the address above). (nrm.se)
  • The International Agency for Research on Cancer (IARC) uses the term "biological resource center" for collections of human cancer samples (13). (scielosp.org)
  • Now an assistant professor of pathology at Harvard Medical School, Bry, 42, has melded her computer knowledge with her clinical and research education to fill a critical need: She has developed an informatics solution to get blood and other biological samples to researchers at a lower cost, and in a shorter time frame, than ever before. (sciencemag.org)
  • Bry "has developed a highly innovative and nationally recognized system to use the biological samples obtained routinely in the course of clinical care as the basis of population-based discovery research," Isaac "Zak" Kohane , director of the Children's Hospital Informatics Program and professor of pediatrics and health sciences and technology at Harvard Medical School, writes in an e-mail. (sciencemag.org)
  • During the last 40 years, The Center for Marine Environmental Studies (CMES), Ehime University collected a variety of environmental and biological material comprising about 1000 species and 100 000 samples from many developing and developed countries and also open seas and oceans all over the world. (rsc.org)
  • The tumor samples were obtained from the Children's Oncology Group Neuroblastoma Tumor Bank. (bio-medicine.org)
  • Maintain a biological samples bank to make specimens available to scientists to evaluate additional potential biological prognostic variables and for the conduct of other research by scientists. (clinicaltrials.gov)
  • To do so, they dipped into SWOG's vast specimen bank - which contains over 800,000 tissue, blood, and other biological samples. (technologynetworks.com)
  • This comprehensive, standardized, longitudinal PD data and biological sample repository is paired with a simple online system that allows researchers to access study data and samples for complementary PD research in their own labs across the globe. (michaeljfox.org)
  • Specimens would be a more accurate term," he corrected, "biological samples freely given to be processed for diagnosis or disease monitoring. (harvard.edu)
  • The ability to access the patient profile of any given specimen is critical to understanding results, as is the ability to search for and find samples that meet research requirements. (labvantage.com)
  • Equally as important is the ability to prove that you've maintained a chain of custody for a specimen or the patient's wishes according to consents granted when the specimen samples were donated. (labvantage.com)
  • The biological samples will help us understand the connectivity of different cold-water coral reef habitats, which will ultimately help with their future management," said on board senior scientist Dr Kerry Howell from Plymouth University Deep Sea Conservation Unit. (marine.ie)
  • and bio-banks are not always readily available as a source of fresh frozen samples. (biomedcentral.com)
  • To overcome some of these critical shortcomings of prospective studies, the use of archival formalin-fixed paraffin-embedded (FFPE) samples offers a potential solution as most hospitals worldwide have collections of FFPE tumor specimens dating back many years. (biomedcentral.com)
  • With nearly a century of experience in biomaterials services and management, we have the expertise needed to authenticate, store, maintain, and globally distribute biological samples. (atcc.org)
  • The Source of specimens will include patients screened for participation on protocols conducted by the AIDS Malignancy Consortium, as well as other patients with HIV infection and cancer who are not eligible for participation in AMC trials, and patients without HIV who have malignancies associated with HIV or with immunosuppression. (clinicaltrials.gov)
  • Biomedical tissue is biological tissue used for organ transplantation and medical research, particularly cancer research. (wikipedia.org)
  • The application of molecular technologies to collections of human biological specimens represents an unparalleled opportunity to discover new ways to prevent, diagnose, and treat cancer and other diseases ( 1 ). (aacrjournals.org)
  • Currently there are no available biological markers that have been satisfactorily validated clinically as 'intermediate end-points' for evaluation of the impact of diet on cancer. (nih.gov)
  • Therefore, there is high scientific value in banking biological specimens for future use in the Malmö Diet and Cancer Study. (nih.gov)
  • The Tissue Banking initiatives have received extensive funding from various initiatives including the Cancer Genome Atlas Project, caHUB, Lung, Melanoma and Head & Neck SPORES, the Gynecologic Disease Program, the Cooperative Prostate Cancer Tissue Resource, the Shared Pathology Informatics Network, the Early Disease Research Network and others. (upmc.edu)
  • Cancer research rely on banked bio-specimens for a wide variety of purposes, including epidemiologic analyses, prevention research, target discovery and validation, research on early carcinogenesis and genetic studies. (omicsonline.org)
  • The specific aims of this project are to create a registry, as well as a blood and a tissue bank for individuals with and at high risk for pancreatic cancer. (columbiasurgery.org)
  • Despite a higher noise level, a set of genes from FFPE specimens correlated very well with the gene profiles obtained from FNAB, and could differentiate breast cancer subtypes. (biomedcentral.com)
  • Our study supports the use of FFPE specimens for the development and refinement of prognostic gene signatures for breast cancer. (biomedcentral.com)
  • Repository is a storage bank used to maintain biological specimens over extended periods of time and under well-controlled conditions. (nasa.gov)
  • This facility houses specimens collected as part of the department's epidemiological studies and clinical trials. (buffalo.edu)
  • In: Biological monitoring methods for industrial chemicals. (cdc.gov)
  • A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. (freepatentsonline.com)
  • Woods Hole, Mass.--The invasive sea squirt that federal and university researchers discovered on Georges Bank a year ago is flourishing in U.S. waters near the U.S.-Canada boundary, a joint research team announced today following a research cruise that concluded last week. (eurekalert.org)
  • Request management in a centralized LIMS is expedited because researchers can more easily search the specimen collections and related clinical data. (labvantage.com)
  • Through this consortium the investigators hope to understand the fundamental biology of these rare diseases and aim to bank long-term observational data and corresponding biological specimens for researchers to access and further enrich. (mayo.edu)
  • Fluids such as blood, blood products and urine are stored in fluid banks under similar conditions. (wikipedia.org)
  • Traci White joins Store-A-Tooth after 11 years as one of the top Clinical Consultants at Viacord, a pioneer in the cord blood banking industry. (prweb.com)
  • White began her career at Viacord as Senior Account Business Manager serving South Florida and was instrumental in the inauguration of private cord blood/cord tissue stem cell banking in the women's healthcare industry by providing educational services to OB/GYNs and their patients. (prweb.com)
  • The present invention is directed to a quantitative testing apparatus and method which may be used for a wide range of diagnostic and prognostic evaluations of various cells, antigens, or other biological materials taken from the human body. (google.com)
  • Selected RNA levels were validated using RT-qPCR, and two public databases were used to demonstrate the prognostic significance of the gene profiles generated from FFPE specimens. (biomedcentral.com)
  • We demonstrated that FFPE specimens retained important prognostic information that could be identified using a recent gene profiling technology. (biomedcentral.com)
  • Resultant biological measures should be incorporated into risk stratification algorithms to inform clinical care and patient stratification for future clinical trials. (nih.gov)
  • Novel tumour biomarkers are expected to be discovered and validated through bio banking, allowing clinical trials to be designed [ 2 , 3 ]. (omicsonline.org)
  • The long-term preservation of representative biological and environmental specimens (i.e., marine sediment, fish, marine animal tissue and fluid) for deferred analysis and evaluation is not only a valuable component of real-time monitoring and basic research, but it also enables investigators to extend their research into the past and provides for future verification of analytical results. (nist.gov)
  • In addition, the convergent development of electronic data processing and biological material preservation gives rise to large-scale storage and leading-edge human tissue studies. (ladydavis.ca)
  • Notably, biomarkers of exposure and early biological effects can be applied to the stored biospecimens. (aacrjournals.org)
  • These specimens will be banked and linked to a clinical data set so that experimental results obtained by analysis of specific specimens can be linked to relevant clinical data. (clinicaltrials.gov)
  • Such achievements, however, depend on the ready availability of high-quality specimens, annotated with relevant clinical data and collected with scrupulous attention to ethical, legal, and social concerns. (aacrjournals.org)
  • Identify and improve access to tumor tissue, biological specimens, and associated clinical outcome data that could be utilized for research by the research community at-large on the pathogenesis of HIV and non-HIV associated malignancies. (clinicaltrials.gov)
  • When it is used for research it is a biological specimen. (wikipedia.org)
  • The most often used indexes for population research cover social and biological sciences. (unc.edu)
  • Cell banks are commonly used within fields including stem cell research and pharmaceuticals, with cryopreservation being the traditional method of keeping cellular material intact. (wikipedia.org)
  • In the fall of 2003, the same research team first spotted this infestation over roughly 6 square miles of ocean bottom during a scientific cruise to study habitats on Georges Bank. (eurekalert.org)
  • Specimens from the ESB are available for research work into environmental contamination and bio-diversity. (nrm.se)
  • In 2005, the National Health Council (CNS) of Brazil approved a resolution to regulate the use of human biological materials in research projects (Resolution CNS 347/05) (1). (scielosp.org)
  • The Organization for Economic Cooperation and Development (OECD) uses the term "biological resource center" (BRC) to refer to, not only repositories, but also suppliers of health research services (12). (scielosp.org)
  • There are two types of national research infrastructure: National Research Facilities and National Biological Collections. (www.csiro.au)
  • CSIRO's National Research Collections Australia (NRCA) comprise six national biological collections and the Atlas of Living Australia (ALA), funded by the National Collaborative Research Infrastructure Strategy (NCRIS). (www.csiro.au)
  • Formal environmental specimen banking is recognized internationally as an integral part of long-term environmental research and monitoring. (nist.gov)
  • Provia Labs' Store-A-Tooth™ dental stem cell banking will be featured as a new product at this week's Greater New York Dental Meeting (GNYDM), exhibiting at booth #3333 to showcase their service and announce their initiative to support diabetes research, 'Stem Cells for a Cure. (prweb.com)
  • The visuals range from firsthand accounts of specimen collections in historical medical museums, to scientific research laboratories, to studies of plant propagation, among other themes concerning life forms and Bio Art. (peterlang.com)
  • In medical research, human bio banking is directed to investigate the genetic, molecular and environmental factors underlying diseases. (omicsonline.org)
  • The Bio banks constitute the infrastructure allowing medical research and biotechnology progresses in human oncology targeted therapy. (omicsonline.org)
  • In Europe, the Consortium BBMRI-ERIC (Bio banking and Bio Molecular Resources Research Infrastructure - European Research Infrastructure Consortium) has been developed, sustained by a forum of EU member states and approved by the European Commission ( http://bbmri.eu/ ). (omicsonline.org)
  • Besides developing the methodology to maintain live specimens in the gene bank, the National Carp Breeding Program has been initiated in cooperation with all the key stakeholders in Hungary, namely the National Association of Fish Producers (HOSZ), the National Institute for Agricultural Quality Control (OMMI), and the Research Institute for Fisheries, Aquaculture and Irrigation (HAKI). (repec.org)
  • The long-run economic costs of AIDS : theory and an application to South Africa ," Policy Research Working Paper Series 3152, The World Bank. (repec.org)
  • Analysis of large amounts of data and specimens increases the statistical power of research outcomes and thereby enhances their validity. (ladydavis.ca)
  • The possibility of correlating banked data and, also, correlating those data and biological material multiplies research resources and improves the chances of gaining new knowledge. (ladydavis.ca)
  • The purpose of this study is to create a Yale University Department of Neurology biological specimen bank and data repository that will be used for current and future research projects involving the study of autoimmune neurological diseases, illnesses and conditions. (yale.edu)
  • In certain clinical and research situations, performing such analyses on archival formalin fixed paraffin-embedded (FFPE) surgical specimens would be advantageous as large libraries of such specimens with long-term follow-up data are widely available. (biomedcentral.com)
  • Toxicology and biological monitoring of metals in humans. (cdc.gov)
  • The scientists observed mats over at least 40 square miles of the gravel substrate on the northern edge of Georges Bank. (eurekalert.org)
  • Cutting-edge and thorough, Stem Cell Banking: Concepts and Protocols is a valuable resource for stem cell scientists and novices to the field, and will help strengthen and maximize their use of existing and future stem cell resources. (springer.com)
  • Scientists who use SWAN Repository specimens can also request data collected at participant's annual visits. (nih.gov)
  • The marine scientists led by the Marine Institute with the National Parks and Wildlife Services, travelled over 1000 nautical miles over three weeks along Ireland's Porcupine Bank and continental slope collecting HD video, sample cores and biological specimens along the shelf edge from 50 locations. (marine.ie)
  • The biological collections at BGBM are seeked by scientists from around the world either by visiting BGBM, by loaning selected specimen or by studying their digital equivalents online. (bgbm.de)
  • Tissue is stored in tissue establishments or tissue banks under cryogenic conditions. (wikipedia.org)
  • The network includes a specimen bank, immunology laboratories and a data analysis center. (nih.gov)
  • Some examples of these include the World Federation for Culture Collections and the International Society for Biological and Environmental Repositories. (wikipedia.org)
  • The ESB has one of the oldest and greatest collections of environmental specimens in the world. (nrm.se)
  • CSIRO also manages over 20 smaller collections of interest that contribute to the discovery, inventory, understanding and conservation of Australia's biological diversity. (www.csiro.au)
  • We increased the proportion of the national biological collections that are digitised. (www.csiro.au)
  • As NIST became more involved with specimen banking, the focus turned toward marine animal collections, including NOAA National Marine Fisheries Service's (NMFS) National Marine Mammal Tissue Bank (NMMTB). (nist.gov)
  • The extensive biological collections at BGBM document the diversity of plants on a world wide scale. (bgbm.de)
  • The biological collections enable systematic studies of the organisms, document their variability and file their evolution in space and time. (bgbm.de)
  • Provides services to modify the murine genome by transgenic approaches for the systematic dissection of the genetic, molecular, cellular and physiological mechanisms underlying complex biological processes. (buffalo.edu)
  • The ability of gene profiling to predict treatment response and prognosis in breast cancers has been demonstrated in many studies using DNA microarray analyses on RNA from fresh frozen tumor specimens. (biomedcentral.com)
  • Ms. White will be responsible for providing resources and support to dentists who offer the Store-A-Tooth service to patients in their practices, as well as educating local families about the powerful choice they can make to bank their children's stem cells when teeth come out. (prweb.com)
  • According to Howard Greenman, CEO of Store-A-Tooth, "Traci's vast knowledge of stem cell banking will prove to be a valuable asset to the South Florida community as she will aid many families in making an informed decision to preserve their children's dental stem cells for future use. (prweb.com)
  • Its dental stem cell banking service, Store-A-Tooth™, gives parents the option to store stem cells today to protect their children's health tomorrow. (prweb.com)
  • For more information about Store-A-Tooth™ dental stem cell banking, please call 1-877-867-5753 or visit us at http://www.store-a-tooth.com or 'Like' Store-A-Tooth at Facebook.com/storeatooth. (prweb.com)
  • By joining the Store-A-Tooth provider network and informing patients about this new opportunity to bank their family's stem cells, dentists can be at the forefront of regenerative medicine and dentistry. (prweb.com)
  • Improving reproducibility and comparability of molecular data as well as designing multicentre studies / trials involving specimen exchanges among different centres is a further major advance in tumour bio banking. (omicsonline.org)
  • This high-throughput molecular technique requires fresh bio-specimens to allow extraction of RNA of sufficient quantity and quality for analysis. (biomedcentral.com)
  • 1979. Quantitative trace analysis of thallium in biological material. (cdc.gov)
  • It is also of importance for studies of biological diversity and the effects of noxious substances on threatened animal species. (nrm.se)
  • Complex behaviors and life histories have long made it challenging to assess key biological parameters and human impacts in marine turtle species. (frontiersin.org)
  • More specifically, the present invention is directed to a method of interactive image analysis for analyzing and quantifying the DNA in specimen cells taken from a person. (google.com)
  • However, the advantage in diagnosis and/or prognosis of abnormal ploidy distributions that a pathologist viewing a specimen under a microscope has is the discerning expertise of a skilled person in classifying cells as normal or abnormal. (google.com)
  • A cell bank is a facility that stores cells of specific genome for the purpose of future use in a product or medicinal needs. (wikipedia.org)
  • Utilizing cell banks also reduces the cost of cell culture processes, providing a cost-efficient alternative to keeping cells in culture constantly. (wikipedia.org)
  • Her understanding of the science of stem cells will aid her in educating the South Florida community on the benefits of banking stem cells from teeth. (prweb.com)
  • Dental stem cell banking gives families the opportunity to store their child's stem cells long after birth for potential use in therapies for conditions such as type 1 diabetes , spinal cord injuries, stroke, heart attack and neurological disorders such as Parkinson's and Alzheimer's. (prweb.com)
  • Dental professionals play an important role in spreading awareness about this option, to give patients the choice to bank their own stem cells from teeth that would otherwise be discarded during routine dental care. (prweb.com)
  • The company partners with dental offices to educate patients about the option to bank their family's stem cells. (prweb.com)
  • Besides satisfying the needs of industry, the live gene bank helped to conserve the biological diversity of Hungarian carp landraces. (repec.org)
  • AAHL continued to play a key role in avian influenza surveillance and diagnostics, testing for exclusion of foot-and-mouth disease and quarantine tests to enable global movements of healthy animals, facilitate import of biological materials, exclude exotic diseases in Australian livestock or characterise viruses detected in our region. (www.csiro.au)
  • This will be supported by a UK virtual Environmental Specimen Bank to facilitate rapid discovery of archived biological specimens. (ceh.ac.uk)
  • The National Stem Cell Bank was established in October 2005 in Madison, Wisconsin in order to serve as a repository specifically for stem cell lines. (wikipedia.org)
  • Stem Cell Banking: Concepts and Protocols aims to contribute to the development of this field by providing information that is essential to establishing a bona fide stem cell bank. (springer.com)
  • White brings over 11 years of experience in stem cell banking to her new role. (prweb.com)
  • 7. The apparatus of claim 1 further comprising a cooling system for keeping the biological specimens in the containers frozen, the cooling system including a coolant reservoir for containing a coolant, wherein the cooling station is adapted to pre-cool the coring bit by contacting the coring bit and the coolant with one another. (freepatentsonline.com)
  • 8. The apparatus of claim 1 wherein the cooling station is adapted to contact the coring bit with a stream of coolant above the biological specimens. (freepatentsonline.com)
  • But even if your husband tells his ex to go to a sperm bank and pick some other superb specimen out of the catalog, it does not solve your essential problem. (slate.com)
  • He has been the Medical Director of the Health Sciences Tissue Bank of the University of Pittsburgh since 1997. (upmc.edu)
  • They were categorically archived, catalogued and stocked in our Environment Specimen Bank ( es -BANK) facility equipped with a −25 °C cold room. (rsc.org)
  • Dr. Dhir is Chief of Pathology at UPMC Shadyside, Director of International Business Development, Director of the Genitourinary Pathology Center of Excellence, Director of the Paraffin Tissue Array Facility, and Director of the Health Science Tissue Bank. (upmc.edu)
  • Advanced Nano Step Specimen Cell 1 Removal: After successfully completing the 35-day Advanced Nano Step experiment run last week, today the Specimen Cell was removed from the Solution Crystallization Observation Facility (SCOF) and stowed until its return on SpX-13. (nasaspaceflight.com)
  • In 2019 she was involved in work to help automate the identification of insects using imaging, testing a convolutional neural network to classify images of insect specimens. (wikipedia.org)
  • If permission were granted, some specimens were aliquoted into vessels and banked for future studies. (cdc.gov)
  • and 4) to aliquot and bank for future studies. (cdc.gov)
  • Leftover specimens are archived for future studies. (clinicaltrials.gov)
  • These resources include vaccine production, preclinical evaluation of vaccines in nonhuman primates and the development of biological and chemical substances called reagents for use in comparative vaccine studies. (nih.gov)
  • Thus, a number of recent studies have started to look into the prospect of overcoming the RNA quality issues in FFPE specimens. (biomedcentral.com)
  • I thought you might be interested in this item at http://www.worldcat.org/oclc/840307092 Title: Monitoring Environmental Materials and Specimen Banking : Proceedings of the International Workshop, Berlin (West), 23-28 October 1978 Author: N -P Luepke Publisher: Dordrecht : Springer Netherlands, 1980. (worldcat.org)
  • Selection of environmental materials and specimens related to terrestrial ecosystems and pollutants or pollutant categories. (worldcat.org)
  • The Environmental Specimen Bank (ESB) is an essential part of the monitoring of contaminants in the Swedish fauna. (nrm.se)
  • The International Environmental Specimen Bank Group (IESB) promotes the world-wide development of techniques and strategies of environmental specimen banking. (nrm.se)
  • IESB is devoted to both, established Environmental Specimen Banks (ESBs) and new ESBs in the planning stages. (nrm.se)
  • Section 1004 of this legislation authorized the National Institute of Child Health and Human Development (NICHD) "to conduct a national longitudinal study of environmental influences (including physical, chemical, biological, and psychosocial) on children's health and development. (aappublications.org)
  • The long-term storage of environmental and human specimens is regarded as the main task of the German Environmental Specimen Bank: The Environmental Specimen Bank provides a continuous historical record of the state of the environment in Germany. (umweltprobenbank.de)
  • The overall goal of SWAN is to describe the chronology of the biological and psychosocial characteristics that occur during midlife and the menopausal transition. (nih.gov)
  • Medical and health history, psychosocial measures, biological measures, and anthropometry are collected during the annual visit. (nih.gov)
  • More productive sources for biomarker-related citations are found in the biological sciences. (unc.edu)
  • Somatic responses, classification networks and image banks are explored as they relate to intersections in visual art and the biological sciences. (peterlang.com)
  • Sabine Flach: What relationship do you think exists between the biological sciences and the physical ones? (peterlang.com)
  • Metal risk assessment of industrialised harbours and coastal marine waters requires the application of robust water quality guidelines to determine the likelihood of biological impacts. (environmental-expert.com)
  • This Funding Opportunity Announcement (FOA) is to promote the development and initial clinical validation of objective biological measures to be used for prognosing, and monitoring recovery of adolescents who either clinically present with or are at risk for developing prolonged/persistent concussive symptoms following exposure to repetitive head impacts and/or concussion. (nih.gov)
  • discovering, characterizing the selectivity and sensitivity, and externally validating biological measures to be used for assessing, prognosing, and monitoring recovery of adolescents who either clinically present with or are at risk for developing prolonged/persistent concussive symptoms following exposure to repetitive head impacts and/or concussion. (nih.gov)
  • 1986. Documentation of the threshold limit values and biological exposure indices. (cdc.gov)
  • However, the major challenge remains of reconstructing past exposure histories either by questionnaires or biomarkers, the latter being generally limited by their inherent biological instability. (aacrjournals.org)
  • 2) Disease-oriented bio banks for epidemiology, based on a large sample number, aimed to identify biomarker exposure, usually following a healthy exposed cohort/case-control design. (omicsonline.org)
  • AAHL continues to maintain or exceed the many regulatory requirements certified by the Department of Agriculture and Water Resources (DAWR), the Office of the Gene Technology Regulator and the Department of Health's Security Sensitive Biological Agents legislation, and all relevant International Organization for Standardization (ISO) accreditation. (www.csiro.au)
  • In: Analysis of hazardous substances in biological materials. (cdc.gov)
  • Cell banks also effectively reduce the frequency of a cell sample diversifying from natural cell divisions over time. (wikipedia.org)
  • The amount of clinical data linked to the sample determinates the availability and biological value of the sample. (omicsonline.org)
  • From managing the storage and maintenance of annotated specimen data to following the chain of custody and making determinations about a sample quickly and accurately, a biobanking LIMS requires standard features to meet the needs of the community. (labvantage.com)