The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
The study of the physical and chemical properties of a drug and its dosage form as related to the onset, duration, and intensity of its action.
The profession of writing. Also the identity of the writer as the creator of a literary production.
Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Intentional falsification of scientific data by presentation of fraudulent or incomplete or uncorroborated findings as scientific fact.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The white of an egg, especially a chicken's egg, used in cooking. It contains albumin. (Random House Unabridged Dictionary, 2d ed)
A heterogeneous mixture of glycoproteins responsible for the gel structure of egg white. It has trypsin-inhibiting activity.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
Proteins found in eggs which are consumed as a food.
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
The common name for the phylum of microscopic unicellular STRAMENOPILES. Most are aquatic, being found in fresh, brackish, and salt water. Diatoms are noted for the symmetry and sculpturing of their siliceous cell walls. They account for 40% of PHYTOPLANKTON, but not all diatoms are planktonic.
A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].
A family of gram-negative bacteria in the order Nitrosomonadales, class BETAPROTEOBACTERIA. It contains a single genus Gallionella.
A hydrated form of silicon dioxide. It is commonly used in the manufacture of TOOTHPASTES and as a stationary phase for CHROMATOGRAPHY.
A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.
A class of annelid worms with few setae per segment. It includes the earthworms such as Lumbricus and Eisenia.
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading.
The unconsolidated mineral or organic matter on the surface of the earth that serves as a natural medium for the growth of land plants.
Drugs considered essential to meet the health needs of a population as well as to control drug costs.
The presence of bacteria, viruses, and fungi in the soil. This term is not restricted to pathogenic organisms.
Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.
An allotropic form of carbon that is used in pencils, as a lubricant, and in matches and explosives. It is obtained by mining and its dust can cause lung irritation.
Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.
A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
Nanometer-scale composite structures composed of organic molecules intimately incorporated with inorganic molecules. (Glossary of Biotechnology and Nanobiotechology Terms, 4th ed)
Individual's rights to obtain and use information collected or generated by others.
The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.
The ability to speak, read, or write several languages or many languages with some facility. Bilingualism is the most common form. (From Random House Unabridged Dictionary, 2d ed)
A verbal or nonverbal means of communicating ideas or feelings.
The study of natural phenomena by observation, measurement, and experimentation.
A course of study offered by an educational institution.
The study of the structure of various TISSUES of organisms on a microscopic level.
An island south of Australia and the smallest state of the Commonwealth. Its capital is Hobart. It was discovered and named Van Diemen's Island in 1642 by Abel Tasman, a Dutch navigator, in honor of the Dutch governor-general of the Dutch East Indian colonies. It was renamed for the discoverer in 1853. In 1803 it was taken over by Great Britain and was used as a penal colony. It was granted government in 1856 and federated as a state in 1901. (From Webster's New Geographical Dictionary, 1988, p1190 & Room, Brewer's Dictionary of Names, p535)
Computer-based representation of physical systems and phenomena such as chemical processes.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.

Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans. (1/3985)

In previous studies, the bioavailability of biotin in humans was estimated from the recovery of biotin in urine; urinary biotin was measured by microbial growth assays or assays of avidin-binding activity. These assays underestimate concentrations of biotin metabolites, which originate from beta-oxidation, sulfur oxidation or a combination. We have developed an HPLC/avidin-binding assay that is specific for biotin and its metabolites. With the use of the HPLC/avidin-binding assay, TLC and derivatization with p-dimethylaminocinnamaldehyde, we have identified and quantitated biotin and metabolites in urine from six healthy adults. Of that total, biotin accounted for 32+/-12%, bisnorbiotin for 52+/-15%, bisnorbiotin methyl ketone for 7.9+/-5.8%, biotin-d,l-sulfoxide for 4.0+/-3.2% and biotin sulfone for 3.6+/-1.9%. After intravenous administration of 18.4 micromol of biotin, the urinary excretion of biotin metabolites increased 21-130 times above baseline values. Because the biliary excretion of biotin is quantitatively minor (1.9+/-0.2% of an intravenous [14C]biotin dose in rats), intravenously administered biotin is not exposed to intestinal microorganisms. Thus we conclude that biotin metabolites in human urine originate from biotin catabolism in human tissues rather than biotin catabolism by intestinal microorganisms. With the use of the HPLC/avidin-binding assay, we estimated the bioavailability of biotin in adults from the urinary excretion of biotin and metabolites after ingestion of 2.1, 8.2 and 81.9 micromol of biotin. These data provide evidence that biotin is nearly completely absorbed.  (+info)

The importance of pyruvate availability to PDC activation and anaplerosis in human skeletal muscle. (2/3985)

No studies have singularly investigated the relationship between pyruvate availability, pyruvate dehydrogenase complex (PDC) activation, and anaplerosis in skeletal muscle. This is surprising given the functional importance attributed to these processes in normal and disease states. We investigated the effects of changing pyruvate availability with dichloroacetate (DCA), epinephrine, and pyruvate infusions on PDC activation and accumulation of acetyl groups and tricarboxylic acid (TCA) cycle intermediates (TCAI) in human muscle. DCA increased resting PDC activity sixfold (P < 0.05) but decreased the muscle TCAI pool (mmol/kg dry muscle) from 1.174 +/- 0.042 to 0.747 +/- 0.055 (P < 0.05). This was probably a result of pyruvate being diverted to acetyl-CoA and acetylcarnitine after near-maximal activation of PDC by DCA. Conversely, neither epinephrine nor pyruvate activated PDC. However, both increased the TCAI pool (1.128 +/- 0.076 to 1.614 +/- 0.188, P < 0.05 and 1.098 +/- 0.059 to 1.385 +/- 0.114, P < 0.05, respectively) by providing a readily available pool of pyruvate for anaplerosis. These data support the hypothesis that TCAI pool expansion is principally a reflection of increased muscle pyruvate availability and, together with our previous work (J. A. Timmons, S. M. Poucher, D. Constantin-Teodosiu, V. Worrall, I. A. Macdonald, and P. L. Greenhaff. J. Clin. Invest. 97: 879-883, 1996), indicate that TCA cycle expansion may be of little functional significance to TCA cycle flux. It would appear therefore that the primary effect of DCA on oxidative ATP provision is to provide a readily available pool of acetyl groups to the TCA cycle at the onset of exercise rather than increasing TCA cycle flux by expanding the TCAI pool.  (+info)

Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations. (3/3985)

High-dose busulphan-containing chemotherapy regimens have shown high response rates in children with relapsed or refractory neuroblastoma, Ewing's sarcoma and medulloblastoma. However, the anti-tumour activity of busulfan as a single agent remains to be defined, and this was evaluated in athymic mice bearing advanced stage subcutaneous paediatric solid tumour xenografts. Because busulphan is highly insoluble in water, the use of several vehicles for enteral and parenteral administration was first investigated in terms of pharmacokinetics and toxicity. The highest bioavailability was obtained with busulphan in DMSO administered i.p. When busulphan was suspended in carboxymethylcellulose and given orally or i.p., the bioavailability was poor. Then, in the therapeutic experiments, busulphan in DMSO was administered i.p. on days 0 and 4. At the maximum tolerated total dose (50 mg kg(-1)), busulphan induced a significant tumour growth delay, ranging from 12 to 34 days in the three neuroblastomas evaluated and in one out of three medulloblastomas. At a dose level above the maximum tolerated dose, busulphan induced complete and partial tumour regressions. Busulphan was inactive in a peripheral primitive neuroectodermal tumour (PNET) xenograft. When busulphan pharmacokinetics in mice and humans were considered, the estimated systemic exposure at the therapeutically active dose in mice (113 microg h ml(-1)) was close to the mean total systemic exposure in children receiving high-dose busulphan (102.4 microg h ml(-1)). In conclusion, busulphan displayed a significant anti-tumour activity in neuroblastoma and medulloblastoma xenografts at plasma drug concentrations which can be achieved clinically in children receiving high-dose busulphan-containing regimens.  (+info)

Bioavailability and toxicity after oral administration of m-iodobenzylguanidine (MIBG). (4/3985)

meta-iodobenzylguanidine (MIBG) radiolabelled with iodine-131 is used for diagnosis and treatment of neuroadrenergic neoplasms such as phaeochromocytoma and neuroblastoma. In addition, non-radiolabelled MIBG, administered i.v., is used in several clinical studies. These include palliation of the carcinoid syndrome, in which MIBG proved to be effective in 60% of the patients. Oral MIBG administration might be convenient to maintain palliation and possibly improve the percentage of responders. We have, therefore, investigated the feasibility of oral administration of MIBG in an animal model. Orally administered MIBG demonstrated a bioavailability of 59%, with a maximal tolerated dose of 60 mg kg(-1). The first and only toxicity encountered was a decrease in renal function, measured by a reduced clearance of [51Cr]EDTA and accompanied by histological tubular damage. Repeated MIBG administration of 40 mg kg(-1) for 5 sequential days or of 20 mg kg(-1) for two courses of 5 sequential days with a 2-day interval did not affect renal clearance and was not accompanied by histological abnormalities in kidney, stomach, intestines, liver, heart, lungs, thymus, salivary glands and testes. Because of a sufficient bioavailability in absence of gastrointestinal toxicity, MIBG is considered suitable for further clinical investigation of repeated oral administration in patients.  (+info)

A phase I study of the lipophilic thymidylate synthase inhibitor Thymitaq (nolatrexed dihydrochloride) given by 10-day oral administration. (5/3985)

2-Amino-3,4-dihydro-6-methyl-4-oxo-5-(4-pyridylthio)-quinazoline dihydrochloride (nolatrexed dihydrochloride, Thymitaq, AG337), a specific inhibitor of thymidylate synthase, was developed using protein structure-based drug design. Intravenously administered nolatrexed is active clinically. As oral bioavailability is high (70-100%), nolatrexed was administered orally, 6 hourly for 10 days, at 3-week intervals, and dose escalated from 80 to 572 mg m(-2) day(-1) in 23 patients. Common toxicity criteria (CTC) grade 3 toxicities included nausea, vomiting, stomatitis and liver function test (LFT) abnormalities. Thrombocytopenia (grade 1 or 2) occurred at doses > or = 318 mg m(-2) day(-1) and neutropenia (grade 2) at 429 and 572 mg m(-2) day(-1). An erythematous maculopapular rash occurred at dosages > or = 318 mg m(-2) day(-1) (7 out of 19 patients). LFT abnormalities occurred in two out of six patients (grade 3 or 4 bilirubin and grade 3 alanine transaminase) at 572 mg m(-2) day(-1). Nolatrexed plasma concentrations 1 h after dosing were 6-16 microg ml(-1), and trough 3-8 microg ml(-1), at 572 mg m(-2) day(-1). Inhibition of thymidylate synthase was demonstrated by elevation of plasma deoxyuridine. Six-hourly oral nolatrexed for 10 days was associated with antiproliferative effects, but nausea and vomiting was dose limiting at 572 mg m(-2) day(-1). Nine patients were treated at 429 mg m(-2) day(-1); three out of nine experienced grade 3 nausea, but 17 out of 22 treatment courses were completed (with the co-administration of prophylactic antiemetics) and this dose level could be considered for phase II testing.  (+info)

Pharmacokinetics of recombinant human granulocyte colony-stimulating factor in rabbits and mice. (6/3985)

AIM: To study the pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhGCSF) in rabbits and mice. METHODS: 125I-rhGCSF was prepared by iodogen method and determined by size exclusive HPLC (SEHPLC). RESULTS: Concentration-time curves after i.v. 125I-rhGCSF in rabbits were best fitted with 2-compartment open model. The alpha and terminal elimination T1/2 were 0.25-0.33 and 3.2-4.6 h, respectively. AUC increased with doses, and Cls and K10 were similar. Tpeak was 0.59 +/- 0.25 h after s.c., and elimination T1/2 was similar to that after i.v. The bioavailability after sc was 1.0. In mice the highest level was found in renal system, the next was bile-enteric system. Levels in lymph nodes, bone marrow, and spleen were approximately equal to or slightly lower than that in plasma, while the levels in brain, fat, and muscles were the lowest. About 68%-86% were recovered in urine and feces. CONCLUSION: Pharamcokinetics of 125I-rhGCSF in rabbits and mice provided a useful index for clinical trial.  (+info)

Pharmacokinetics of bendazac lysine in 10 Chinese young men. (7/3985)

AIM: To compare the pharmacokinetics of domestic and imported tablets of bendazao lysine (BL). METHODS: A single oral dose of 500 mg BL of this 2 kinds of tablets was given to 10 Chinese volunteers of Han nationality in a randomized crossover study. Plasma levels were determined with HPLC-UV method. Data were analyzed automatically by using a CAPP program on microcomputer. RESULTS: The plasma concentration-time curve was fitted to 2-compartment open model, and the major pharmacokinetic parameters of domestic and imported BL tablets were shown respectively as following: Cmax 66 +/- 16 and 65 +/- 8 mg.L-1; Tmax 0.98 +/- 0.22 and 0.98 +/- 0.21 h; T1/2 beta 6.2 +/- 1.8 and 6.2 +/- 1.7 h; AUC 335 +/- 47 and 337 +/- 58 mg.h.L-1. There was no significant difference between domestic and imported tablets. The bioavailability of the domestic vs that of the imported tablet was 99 +/- 12%. The unchanged BL in urine were about 5.4% and 5.6% respectively of the dosage in 24 h after a single oral dose. CONCLUSION: The two kinds of tablets had the same biological effects.  (+info)

A study of the relative bioavailability of cysteamine hydrochloride, cysteamine bitartrate and phosphocysteamine in healthy adult male volunteers. (8/3985)

AIMS: Cysteamine, the only drug available for the treatment of cystinosis in paediatric patients, is available as the hydrochloride, the bitartrate and as sodium phosphocysteamine salts. It has been suggested that cysteamine bitartrate and phosphocysteamine are better tolerated and may have a better bioavailability than cysteamine hydrochloride. This has, however, never been demonstrated. METHODS: We compared the pharmacokinetics and tolerance of these three formulations of cysteamine in 18 healthy adult male volunteers in a double-blind, latin-square, three-period, single oral dose cross-over relative bioavailability study. RESULTS: No statistical difference was found between relative bioavailabilities, AUC (0, infinity) (geometric mean and s.d. in micromol l(-1) h: 169+/-51, 158+/-46, 173+/-49 with cysteamine hydrochloride, phosphocysteamine and cysteamine bitartrate respectively), Cmax (geometric mean and s.d. in micromol l(-1); 66+/-25.5, 59+/-12, 63+/-20) and tmax (median and range in h: 0.88 (0.25-2), 1.25 (0.25-2), 0.88 (0.25-2)) with each of the three forms of cysteamine tested. Bioequivalence statistics (90% confidence intervals) showed non equivalence of Cmax of cysteamine base as the only non equivalence of pharmacokinetics between the three formulations: 90% CI for Cmax relative ratios to cysteamine hydrochloride were [75.6-105.81 for phosphocysteamine and [74.2-124.2] for cysteamine bitartrate. The only significant adverse event was vomiting whose frequency was inversely correlated with body weight (Spearman's r=-0.76, P<0.001). The nature of the salt tested did not influence vomiting. CONCLUSIONS: While none of the three forms of cysteamine tested has a clear advantage over the others in terms of pharmacokinetics and tolerance profile, this should now however be addressed in patients treated for cystinosis during repeat administrations.  (+info)

Wheat, a tetany prone forage, and orchardgrass, a non-tetany prone forage, were cut at three stages of maturity to determine the magnesium availability in these forages for lambs. The forages were dried in forced air ovens and ground through a 2.5 cm screen. The nitrogen contents of the forages were not significantly different between forages but decreased quadratically with maturity in wheat (P < .Ol) and linearly in orchardgrass (P < .Ol). Nonprotein nitrogen was significantly higher in wheat than in orchardgrass. The magnesium content of the wheat was lower (P < .O1) than orchardgrass (.14 vs .21%). Magnesium content in wheat was similar at all maturities but decreased with maturity in orchardgrass. Potassium, calcium and phosphorous levels in the forages were similar between wheat and orchardgrass but decreased with advancing maturity in both forages.. In two metabolism trials with 18 wether lambs, the biological availability of magnesium was determined for the two forages cut at three ...
De Nucci, G., Moraes, M. E. A., Lerner, F., Zappi, E. A., Ribeiro, W., Moraes, E. O., & Frota, F. A. B. (2000). Comparative bioavailability of two capsule fluconazole formulations in human healthy. Arzneimittel-Forsch, 11, 1028-1032 ...
In the dietary and beverage industry, and food in general, the supply of minerals is usually made through inorganic salts. However, these salts are inefficient as they are poorly absorbed (bioavailability).. As a result, the industry has been moving for some time towards other alternatives to solve this problem: organic salts.. For this reason, in Quimidroga we incorporated in its moment a wide range of organic salts as a contribution of minerals for feeding by Jungbunzlauer. These are salts obtained by fermentation with greater bioavailability than their corresponding inorganic salts. For example, calcium citrate absorbs between 22% and 27% more than calcium carbonate.. Now, given the growing demand for mineral beverages and responding to their needs, Jungbuzlauer has expanded its range of organic salts with the launch of magnesium lactate and zinc lactate, which in addition to good bioavailability, offers greater solubility compared to other organic salts.. An added advantage of these organic ...
Therefore, a drug given by the intravenous route will have an absolute bioavailability of 100% (f = 1), whereas drugs given by other routes usually have an absolute bioavailability of less than one. If we compare the two different dosage forms having same active ingredients and compare the two drug bioavailability is called comparative bioavailability.. Although knowing the true extent of systemic absorption (referred to as absolute bioavailability) is clearly useful, in practice it is not determined as frequently as one may think. The reason for this is that its assessment requires an intravenous reference, that is, a route of administration that guarantees that all of the administered drug reaches the systemic circulation. Such studies come at considerable cost, not least of which is the necessity to conduct preclinical toxicity tests to ensure adequate safety, as well as there being potential problems due to solubility limitations. These limitations may be overcome, however, by administering ...
Article outlining considerations for API solubility and bioavailability enhancement during the formulation development of drug molecules.
The primary objective of this study is to compare the bioavailability of a test formulation of Buprenorphine Naloxone Sublingual (SL) spray to that of a single
This trial will investigate the pharmacokinetics and pharmacodynamics effects of salmeterol/fluticasone propionate [Seretide; GlaxoSmithKline] delivered by
At screening and check-in for each period, subjects must have blood pressure and pulse rate within the following ranges: Systolic blood pressure (110-150 mmHg); Diastolic blood pressure (70-95 mmHg); Pulse (50-105 bpm). Minor deviations (1-3 mmHg) at check-in may be acceptable at the discretion of the physician investigator. For all except the first period check-in, if a subjects vital signs measurements fall outside the range specified above, the subject may, at the discretion of the physician investigator, be allowed to remain enrolled until 0-hour measurements are made. If the 0-hour protocol vital signs requirements are met, the investigator may allow dosing and the subjects continuation in the study. If 0-hour vital signs requirements are not met, the subject will not be dosed and must be withdrawn from the study. The blood pressure and pulse will be measured after the subject has been seated at least three minutes. Subjects with blood pressure and pulse measurements outside the ranges ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Gu L, Pan C, Su Y, Zhang R, Xiao H, McClements DJ, Yang Y. In Vitro Bioavailability, Cellular Antioxidant Activity, and Cytotoxicity of ß-Carotene-Loaded Emulsions Stabilized by Catechin-Egg White Protein Conjugates. J Agric Food Chem. 2018 Feb 21; 66(7):1649-1657 ...
Lexaira Bioscience says its DehydraTECH platform has demonstrated significant improvements to the bioavailability of cannabinoids, and could be applied to other pharmaceuticals.
The most complete multinutrient formulation for men of all ages. Contains a broad spectrum of food based, highly bioavailable nutrients.
The worlds first wiki where authorship really matters. Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts.
Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process ...
Resveratrol has emerged as a leading candidate for improving healthspan through potentially slowing the aging process and preventing chronic diseases. The poor bioavailability of resveratrol in humans has been a major concern for translating basic science findings into clinical utility. Although a number of positive findings have emerged from human clinical trials, there remain many conflicting results, which may partially be attributed to the dosing protocols used. A number of theoretical solutions have been developed to improve the bioavailability of resveratrol, including consumption with various foods, micronized powders, combining it with additional phytochemicals, controlled release devices, and nanotechnological formulations. While laboratory models indicate these approaches all have potential to improve bioavailability of resveratrol and optimize its clinical utility, there is surprisingly very little data regarding the bioavailability of resveratrol in humans. If bioavailability is indeed a
Highly bioavailable magnesium chelate for sensitive individuals.* Highly bioavailable magnesium chelate* Supports metabolism of carbohydrates, amino acids and fats* Made with hypoallergenic, vegan ingredients Magnesium (glycinate) is a highly bioavailable magnesium chelate, which supports the metabolism and utilization
Quote from Gordon Bates, President, Chemical Division, Lonza Pharma & Biotech:. Chemistry is core to Lonza, and we continue to innovate and invest in flexible small molecule services and site network infrastructure that benefit our customers. We are pleased to launch SimpliFiH Solutions, which integrates our core capabilities and expertise in bioavailability enhancement and drug substance development, and accelerates the first-in-human pathway for candidate molecules.. Quote from Dr. Christian Dowdeswell, VP and Head of Dosage Forms & Delivery Systems, Lonza Pharma & Biotech:. The majority of preclinical candidate molecules require bioavailability enhancement, many even for early phase studies. We have designed SimpliFiH Services to meet the needs of customers for flexible, truly integrated packages that address the bioavailability challenge in a time- and cost-efficient manner.. Basel, Switzerland, 30 April 2019 - Lonza Pharma & Biotech announced the launch of SimpliFiHTM Services, ...
Checkout some of the amazing ingredients that every jar of EverPup® contains to make it the ultimate dog supplement for dogs of all ages. With no muss and no fuss, EverPup may be able to replace several other individual supplements you may now be giving. Especially since EverPup is formulated for high bioavailability, using our technology Biovadex™! Because EverPup is formulated with Biovadex, the ingredients in EverPup are highly bioavailable which means they can perform optimally.. ...
Please note that Lonza has updated its Privacy Policy. By visiting our website or using services provided by Lonza, you are accepting the practices described in the Privacy Policy.. We also use cookies on our websites. Cookies allow us to give you the best browsing experience and help us to understand how you use our site. You can disable cookies but parts of our website may not work. Please read our updated Cookies Policy for information about which cookies we use and the information we collect. By continuing to use this website, you agree that we may store and access cookies on your device.. By clicking I Agree, you confirm that you are above the age of 16, that you have read and understood the Privacy Policy and the Cookies Policy, and that you agree to the collection, use and processing of your Personal Information by Lonza in accordance with said policies.. ...
Several oral ivermectin (IVM) formulations for use in sheep are available in the pharmaceutical veterinary market in different countries. All of them are indicated at the same dose rate to treat the gastrointestinal nematodes. However, there is a lack of information on the relative systemic exposure (plasma bioavailability) and clinical efficacy among oral formulations routinely used in sheep. The main goal of the work reported here was to perform a pharmaco-parasitological assessment of three different IVM oral formulations in lambs infected with multiple resistant gastrointestinal nematodes. The comparative drug systemic exposure (IVM plasma concentrations) and nematodicidal efficacies (clinical efficacy) in lambs were determined for a reference (RF) and two different test (T1, T2) IVM oral formulations. One hundred and fifty six (n= 156) healthy Corriedale lambs, naturally infected with multiple resistant gastrointestinal nematodes were allocated into four experimental groups (n=39). Animals in each
The number of poorly water-soluble drug substances in the pharmaceutical pipeline is increasing, and thereby also the need to design effective drug delivery systems providing high bioavailability. One favourable formulation approach is preparation of solid dispersions, where dispersing a poorly water-soluble drug in a water-soluble polymer matrix improves the dissolution behaviour and the bioavailability of the drug. However, in order to take full advantage of such formulations the impact of material properties on their performance needs to be investigated.. An experimental toolbox has been designed, and applied, for analysing the processes which govern the behaviour of solid pharmaceutical formulations in general, and that of solid dispersions in particular. For the purpose of monitoring multifaceted phenomena in situ during tablet dissolution, nuclear magnetic resonance (NMR) spectroscopy and NMR imaging are superior to many other techniques, both on macroscopic and molecular levels. The ...
The bioavailability of an AA refers to the proportion of that AA that is in a form that can be digested, absorbed, and used for metabolic functions.1-1-1 Bioavailability coefficients of AAs in feedstuffs are determined in slope ratio growth assays. These assays are laborious and time consuming and only allow determination of the bioavailability of a single AA at a time, which is costly. Consequently, there are only a limited number of ingredients and AAs for which bioavailability coefficients have been determined and such coefficients of AA are not routinely used in feed formulation.. The use of bioavailability coefficients is important for heat-processed or long-stored ingredients because of the negative impact of these treatments on the bioavailability of the AA lysine. Lysine is rendered biologically unavailable by complexing with reducing compounds in the feed.. There are considerable efforts to develop simpler methods for estimating AA bioavailability in feedstuffs. A method known as the ...
At latest update, relevant published data on excretion into breast milk were not found. A high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infants plasma from ingested milk, except in prematures or newborns who may show an increased absorption. Case report of kidney function impairment of a baby whose mother had taken Telmisartan in pregnancy. Until more data on this medication is available, safer alternative drugs are preferred, especially in premature babies or during the neonatal period. Should an ARA-II medication (Sartan type) be necessary, the associated risk may be decreased by choosing the one with a favorable pharmacokinetics (shorter half-life elimination time and lower bioavailability) like Eprosartan and Losartan
Which antibiotics have good / near 100% oral bioavailability? Antibiotics with enhanced oral bioavailability allows conversion to oral therapy once a patient meets defined clinical criteria. This can result in reduced length of hospital stay, health care costs, and potential complications due to intravenous access.
Glucopro is a combination of Glucosamine with high bioavailability and Inulin that promotes and supports healthy joints and a good intestinal flora.
OUR FLAGSHIP ACTIVES. GIVOMAG (magnesium glycerophosphate) is a highly bioavailable magnesium chelate with no side effects on the metabolism, and is part of the 3rd generation mineral salts, called premium. Its effectiveness is proven by clinical studies, and a study carried out with LALLEMAND has proven its synergistic effect with probiotics, thanks to the presence of phosphorus in its composition. It does not contain additives and has a very low level of heavy metals. ISALTIS owns the GIVOMAG trademark and can authorize its use under license.. GIVOMAG has its own website: www.givomag.com for more information. GIVOCAL (calcium glycerophosphate) is a highly bioavailable calcium chelate with no side effects on the metabolism, and is part of the 3rd generation mineral salts, called premium. It is in particular the salt of choice for the most sensitive applications (example: milk for premature babies or babies suffering from serious diseases). The fact that it contains phosphorus and calcium in ...
Pregnancy is a period of increased metabolic demands, with changes in the womans physiology and the requirements of a growing fetus. Nutritional requirement in pregnancy increases for carbohydrate, vitamins and micronutrients especially for Iron, Zinc and Folic acid etc. Presenting R.B.TONE forte tablets containing ferrous ascorbate providing 100 mg of elemental iron which is integral part of many proteins and enzymes that maintain good health. Ferrous ascorbate have high bioavailability with least GI side effects. Folic acid is vital for cell division and growth while zinc is essential for many functions, including growth and neurobehavioral development, immune and sensory function. Thus combination in R.B. TONE FORTE improves fetal growth and develops immune system ensuring expected outcome of pregnancy - no maternal complication and healthy baby ...
Product description Magnesium (glycinate) is a highly bioavailable magnesium chelate, which supports the metabolism and utilization of carbohydrates, amino acids and fats for energy. Magnesium (glycinate) helps activate enzymes for physiological functions including cardiac health.* Highly bioavailable magnesium chelate
Buy Maclar Online! Maclar is a semisynthetic macrolide antibiotic, structurally very similar to erythromycin. The absolute bioavailability of Maclar after oral administration is 50-55%, which probably underestimates its systemic activity, as it undergoes extensive first pass metabolism to its active metabolite, 14-hydroxyMaclar.
Muscle repair and protein replacement: Currently, this is the main goal sought by the Test Boost Elite consumers and was discovered through research carried out in the elderly, aiming to maintain their muscle strength and avoid accidents such as falls, so common at this age.. In this research, the researchers linked low levels of testosterone with lower muscle strength, thus indicating that it increases muscle capacity and function. Because it is a supplement of high biological value, when it is ingested by bodybuilders, it restores eventual muscle losses through the training effort, in order to reduce catabolism. The plasma biological availability of this protein also helps in gaining muscle mass.. - Decreased post workout symptoms: A survey conducted by Ball State University compared the symptoms of bodybuilders after a week of overtraining. While one group took Test Boost Elite supplement after exercise, the other group took a placebo, without either group knowing which of the two products ...
Muscle repair and protein replacement: Currently, this is the main goal sought by the Test Boost Elite consumers and was discovered through research carried out in the elderly, aiming to maintain their muscle strength and avoid accidents such as falls, so common at this age.. In this research, the researchers linked low levels of testosterone with lower muscle strength, thus indicating that it increases muscle capacity and function. Because it is a supplement of high biological value, when it is ingested by bodybuilders, it restores eventual muscle losses through the training effort, in order to reduce catabolism. The plasma biological availability of this protein also helps in gaining muscle mass.. - Decreased post workout symptoms: A survey conducted by Ball State University compared the symptoms of bodybuilders after a week of overtraining. While one group took Test Boost Elite supplement after exercise, the other group took a placebo, without either group knowing which of the two products ...
The overall objective of this project was to investigate the role of locally derived growth factors and extracellular matrix proteins in regulating prepubertal heifer mammary development. In the first experiment, short-term treatment of heifers with GH or E increased proliferation of mammary epithelial cells. Coinciding with increased epithelial cell proliferation, IGF-I protein increased and IGFBP-3 protein decreased within mammary tissues. Thus, proliferation was associated with an apparent net increase in the biological availability of IGF-I within the mammary gland. In the second experiment, decreased mammary development and epithelial cell proliferation in response to ovariectomy coincided with decreased mammary expression of IGF-I mRNA and decreased binding of IGF-I to mammary microsomes. Taken together, these results imply an important role for locally derived IGF-I in regulating heifer mammary development. However, in contrast to our hypothesis, IGF-I mRNA did not differ between cleared ...
There are few p.o. administered chemotherapeutics currently available with demonstrated efficacy against i.c. tumors. The principal finding in our study is that ZD1839, a p.o.-active EGFR-TKI, is efficacious against i.c. tumors expressing the wild-type EGFR. This is important not only for EGFR-expressing primary malignant tumors of the CNS but also metastatic tumors that also frequently overexpress EGFR and that commonly seek refuge within the CNS. Previous studies have shown that oral administration of ZD1839 to rats (5 mg/kg) yields a terminal half-life of approximately 3-13.8 h in male animals and 5-8.2 h in female animals (data on file at AstraZeneca). The absolute bioavailability after oral dosing at 5 mg/kg was 49.8%. Consequently, when dosage was increased to 12.5 mg/kg, the absolute bioavailability was 76.7 and 87.6% in male and female animals, respectively. On the basis of this information, we had reason to believe that in our experiments treating with nontoxic doses 10-20-fold higher ...
Clinical Benefits: ● High bioavailability and absorption ● Protecting nutrients against the harsh environment of the GI tract ● Increased uptake into cells ● Liposomes can be formulated to hold both water & fat soluble nutrients ● Enhanced compliance for those who have trouble swallowing large tablets ● Less drug-nutrient interactions Overview:​ In todays health and wellness landscape, supplements are widely used and consumed. Two out of three Americans take some kind of supplement everyd
Description CalVita® is a combination based on calcium salts, phosphorus, vitamin D3 and bamboo dry extract, which has a high-efficiency thanks to its high bioavailability. This supplement is formulated to help improve bone health naturally. Instructions Take 2 to 4 tablets a day with food and a large glass of water, s
Ok so, Noopept has been proven to cause minimal negative effects when used based on recommended doses and has a really low toxicity levels.. A lot users who know anything about other Racetams, like Piracetam and Oxiracetam for example, are probably going to know that these types of nootropics have headache as a common side effect.. Noopept, on the other hand, can reduce headaches or not cause them at all.. Its able to avoid headaches because Noopept works to affect Glutamate and not Acetylcholine neurotransmitters that are going to use up your brains supply of choline.. Also, Noopept doesnt lead to digestive problems when it is being used at the ideal dosage.. Because of its really high bioavailability level almost all of it is going to get soaked up down in the GI tract and before it goes toward the brain so you probably wont have any problems.. With that being said there have been cases of where people who take abnormally large doses of Noopept do experience upset stomach and GI tract ...
Ok so, Noopept has been proven to cause minimal negative effects when used based on recommended doses and has a really low toxicity levels.. A lot users who know anything about other Racetams, like Piracetam and Oxiracetam for example, are probably going to know that these types of nootropics have headache as a common side effect.. Noopept, on the other hand, can reduce headaches or not cause them at all.. Its able to avoid headaches because Noopept works to affect Glutamate and not Acetylcholine neurotransmitters that are going to use up your brains supply of choline.. Also, Noopept doesnt lead to digestive problems when it is being used at the ideal dosage.. Because of its really high bioavailability level almost all of it is going to get soaked up down in the GI tract and before it goes toward the brain so you probably wont have any problems.. With that being said there have been cases of where people who take abnormally large doses of Noopept do experience upset stomach and GI tract ...
Raw Hemp Protein High Bioavailability (absorption into body) No psychotropic reaction - they are safe and healthy to eat Raw, Cold-processed Contains a Complete Amino Acid Profile Including the 9 Essential Amino Acids Ideal 3:1 Omega-3 vs. Omega-6 fatty acids Rich in GLAs (Gamma-Linoleic Acids) The hemp seeds, from wh
Dairy-free, great-tasting vegetarian protein powder with non-GMO pea yellow peas. High bioavailability and digestibility and a wide array of amino acids, very similar to whey. Supports healthy cholesterol and blood [...] ...
You should seize only do a weakly buffered Kerasal like Salicylic acid and urea topical. Salicylic acid and although urea topical is uniquely formulated with our bema drug delivery technology that allows approximately for assessing high bioavailability of Salvax duo in the bloodstream, and beliefs represents an important new option for patients and healthcare providers. Read More. ...
GSK2118436 is an orally administered, potent and selective small molecule BRAF inhibitor that is currently being developed for the treatment of BRAF mut
SmartLeef™ Premium Hemp Extract is made from the highest quality hemp oil, with 4.1mg of naturally-occurring CBD and other cannabinoids in each dropper full. You can trust our high bioavailability Biova™ Hemp Extract to absorb quickly and completely into your endocannabinoid system leaving your body feeling relaxed and
Dr. David Hough, the crew chief on Janssens esketamine job, absolutely thinks so. He touts esketamines high bioavailability- which means that far more on the drug will make its way to the brain-and many stellar quantities: a sixty to 70 p.c response charge and 6 to 8 months of http://trainer-albuquerque60371.blogolize.com/The-2-Minute-Rule-for-start-a-ketamine-clinic-9793483 ...
Clinical trial: Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers
Comparative Bioavailability of Two Oral Oseltamivir Formulations: Commercial Capsules and an Emergency Solution Prepared During the 2009 Influenza a (H1n1) Outbreak in Mexico Abstract.
Bioavailability refers to how easy it is for the body to digest, absorb and use a protein in its metabolic processes. Some foods have a greater bioavailability than others. Animal proteins like milk are known to have high bioavailability, meaning that they support muscle building.. Researchers from the University of Exeter compared milk protein with Mycoprotein - the patent-protected protein used in Quorn products - and found equivalent​ bioavailability.. Detailing the study, which was published in British Journal of Nutrition​, the researchers said that they investigated the impact of mycoprotein ingestion, in a dose-response manner, on acute postprandial hyperaminoacidaemia and hyperinsulinaemia.. In all, 12 healthy young men completed five experimental trials in a randomised, single-blind, cross-over design. During each trial, volunteers consumed a test drink containing either 20 g milk protein, mass matched (not protein matched due to the fibre content) mycoprotein, or a protein ...
There are some good choices today for curcumin supplements designed to improve bioavailability, much better than the options that existed even just five years ago. But even with these choices, if you are aiming to maintain significant levels of curcumin in your blood at all times for maximum effect, you are going to need to take two or three doses per day spaced evenly.. Ive not noted any particular digestive upset from taking curcumin with other supplements without a big meal, but this varies from person to person and also depends upon the other supplements you are taking. If you find that you need to take it with some food to minimize digestive upset, Id suggest you try taking one dose in the morning with breakfast and another shortly before bedtime with a small protein-rich snack with some fat content such as cottage cheese. If you choose to take a third dose each day, take it with an afternoon snack or an early dinner.. Consider taking curcumin along with other beneficial oils and fats to ...
As stated in the comments by Eliane B., testosterone can actually be administered orally when an undecanoate ester is attached. The reason regular testosterone cannot be adminstered orally is because it undergoes extensive first pass metabolism (oxidation of the 17b-hydroxyl group to a 17-keto group, catalyzed by 17b-hydroxysteroid dehydrogenase enzymes, which are active in the liver). The undecanoate ester makes the substance lipophilic enough to be transported by the lymphatic system to the circulation after absorption by the intestines. Without the ester it will first reach the liver via the portal vein, thus exposing it to first pass metabolism. Nevertheless, bioavailability of oral testosterone undecanoate is estimated to be less than 10% [1].. Besides that, there are also derivates of testosterone which have a high oral bioavailability. These derivates have an alpha-oriented alkyl group, usually methyl, at position C-17, which retards hepatic metabolism. However, this can lead to ...
IntroductionMisoprostol (Cytotec) was primarily made for treating gastric ulcers. However today it is mostly used for abortion, treating postpartum hemorrhage, and for induction of labor. The tablet contains 200 µg of misoprostol, yet the dosages used for induction of labor are much smaller (25-50 µg), leading to uncertainty of dosage in daily use.AimTo evaluate and compare the relative bioavailability of two misoprostol products (Angusta 25 µg and Cytotec 200 µg tablets) administered orally or sublingually given in a daily clinical setting to women admitted for induction of labor at term.MethodsWomen carrying a live, singleton fetus in a cephalic position and with a gestational age between 259 and 296 days were included. Blood samples were collected at 0, 5, 10, 20, 30, 40, 50, 75, 100, 120, 180, and 240 minutes. A serum analytical assay was performed and pharmacokinetic parameters were calculated. Patients were assigned to one of three groups.ResultsA total of 72 patients were included. No
Sigma-Aldrich offers abstracts and full-text articles by [Stavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J King, Jonathan E Brown, Michael N Clifford].
The current study indicates that administration of the dual ABCB1 and ABCG2 inhibitor tariquidar results in a statistically significantly increase in plasma, liver and brain exposure to imatinib. Since imatinib is known to have very high bioavailability (approximately 98%) [1], it is likely that the difference in plasma AUC is due to modified distribution and/or elimination of the drug, rather than a change in the extent of intestinal absorption. This hypothesis is supported by the fact that tariquidar increased the peak plasma concentration of imatinib by less than 20% and this change was not statistically significant. As expected, there was also no apparent change in the rate of absorption. Considering that imatinib is effluxed by both ABCB1 and ABCG2, the almost complete bioavailability may seem somewhat surprising. However, it is possible that the high concentrations of imatinib in the gut are actually leading to localized inhibition of these transporters, as has been suggested by inhibition ...
General Absorption Pravastatin sodium is administered orally in the active form. In studies in man, peak plasma pravastatin concentrations occurred 1 to 1.5 hours upon oral administration. Based on urinary recovery of total radiolabeled drug, the average oral absorption of pravastatin is 34% and absolute bioavailability is 17%. While the presence of food in the gastrointestinal tract reduces systemic bioavailability, the lipid-lowering effects of the drug are similar whether taken with or 1 hour prior to meals.. Pravastatin plasma concentrations, including area under the concentration-time curve (AUC), Cmax, and steady-state minimum (Cmin), are directly proportional to administered dose. Systemic bioavailability of pravastatin administered following a bedtime dose was decreased 60% compared to that following an AM dose. Despite this decrease in systemic bioavailability, the efficacy of pravastatin administered once daily in the evening, although not statistically significant, was marginally more ...
General Absorption Pravastatin sodium is administered orally in the active form. In studies in man, peak plasma pravastatin concentrations occurred 1 to 1.5 hours upon oral administration. Based on urinary recovery of total radiolabeled drug, the average oral absorption of pravastatin is 34% and absolute bioavailability is 17%. While the presence of food in the gastrointestinal tract reduces systemic bioavailability, the lipid-lowering effects of the drug are similar whether taken with or 1 hour prior to meals.. Pravastatin plasma concentrations, including area under the concentration-time curve (AUC), Cmax, and steady-state minimum (Cmin), are directly proportional to administered dose. Systemic bioavailability of pravastatin administered following a bedtime dose was decreased 60% compared to that following an AM dose. Despite this decrease in systemic bioavailability, the efficacy of pravastatin administered once daily in the evening, although not statistically significant, was marginally more ...
Heme iron has been identified in many plant sourcesmost commonly in the root nodules of leguminous plants, such as soy. Our objective was to test the effectiveness of soy root nodule (SRN) and purified soy hemoglobin (LHb) in improving iron bioavailability using an in vitro Caco-2 cell model, with ferritin response as the bioavailability index. We assessed bioavailability of iron from LHb (either partially purified (LHbA) or purified (LHbD)) with and without food matrix and compared it with that from bovine hemoglobin (BHb), ferrous sulfate (FeSO4), or SRN. Bioavailability of each treatment was normalized to 100% of the FeSO4 treatment. When iron sources were tested alone (100 ug iron/mL), ferritin synthesis by LHbD and BHb were 19% (P | 0.05) and 113% (P | 0.001) higher than FeSO4, respectively. However, when iron sources were used for fortification of maize tortillas (50 ppm), LHbA and BHb showed similar bioavailability, being 27% (P | 0.05) and 33% (P | 0.05) higher than FeSO4. Heat treatment had no
meilleur sites de piratage. http://testadsl.menara.ma/speed.php http://www.ratiatum.com/: pir to. such as children who pass to Hutchison Rudimentary School.Lisinopril hctz makes me tired Lisinopril make me tired Lisinopril. you`ll have to deal with it and wait for these phase to pass. Why dows lisinopril make.Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy. Diabetes Care, Dec 2000.. it was first described in medical literature. thus taking advantage of the blockade exerted by quinidine on the first-pass hepatic metabolism of.Emergency Cardiac Drugs by. • Oral nitroglycerin undergoes significant first-pass metabolism and has less than 1%. (Vasotec) • Lisinopril.. ...
First-pass hepatic retention of glucose had previously been measured indirectly from the appearance of ingested labelled glucose into the systemic circulation. To determine the accuracy of the procedure, results obtained by this indirect method were compared with those of direct measurement of hepatic retention of labelled glucose given by instantaneous injection into the portal vein. In the rat, the indirect procedure gave a value of 13.7 +/- 2.3%. In the direct method, [14C]glucose was injected intraportally together with [3H]sucrose as a marker of extracellular distribution. Hepatic content of both labels was maximal immediately after administration; the content of sucrose fell to basal values by 15 s, indicating that the injected bolus had passed through the liver; the content of [14C]glucose continued to fall for 90 s. The difference in tissue retention between glucose and sucrose, representing intracellular glucose, was constant from 90 to 180 s, and indicated a first-pass retention of 13 ...
Fortified-blended foods (FBFs), grain-legume porridges (most commonly corn and soy), are frequently used for food aid purposes. Sorghum and cowpea have been suggested as alternative FBF commodities because they are drought-tolerant, grown locally in food aid receiving countries, and are not genetically modified. The objective of this thesis was to determine the protein quality and iron bioavailability of newly formulated, extruded FBFs in broiler chickens, which have been suggested as a good model for assessing iron bioavailability. Five FBFs were formulated to contain whey or soy protein to compare protein quality, sugar, oil, and an improved micronutrient premix. These included three white sorghum-cowpea FBFs; two were extruded with either whey protein concentrate (WSC) or soy protein isolate (WSC+SPI) added, one was non-extruded (N-WSC). Two others were white sorghum-soy (WSS) and corn-soy (CSB14) FBFs. Two additional white-sorghum cowpea FBFs were reformulated and over-processed to contain ...
Curcumin is a molecule that is notoriously difficult to absorb. There is evidence that turmeric in its basal state, when used as a persistent part of the diet, can exert health benefits, including antimicrobial effects​​, even with its poor absorption profile. The curcumin content of turmeric samples tested in India recently varied widely​​, from a low of about 2.5% to a high of almost 9% by weight. The discussion among researchers then has been what dosages in a dietary supplement application are effective, given that so little of the active ingredients actually end up crossing the blood barrier. Despite its reported benefits via inflammatory and antioxidant mechanisms, one of the​ major problems with ingesting curcumin by itself is its poor bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. Several agents have been tested to improve curcumins bioavailability by addressing these various mechanisms, ​Drs Kalman and ...
Therefore, a drug given by the intravenous route will have an absolute bioavailability of 100% (f = 1), whereas drugs given by other routes usually have an absolute bioavailability of less than one. If we compare the two different dosage forms having same active ingredients and compare the two drug bioavailability is called comparative bioavailability.[citation needed] Although knowing the true extent of systemic absorption (referred to as absolute bioavailability) is clearly useful, in practice it is not determined as frequently as one may think. The reason for this is that its assessment requires an intravenous reference; that is, a route of administration that guarantees all of the administered drug reaches systemic circulation. Such studies come at considerable cost, not least of which is the necessity to conduct preclinical toxicity tests to ensure adequate safety, as well as potential problems due to solubility limitations. These limitations may be overcome, however, by administering a ...
The growth promoting hormone Insulin-like growth factor-1 (IGF-1) similar to insulin may be an important regulator of nitric oxide (NO) bioavailability. We have previously reported in two murine models of reduced IGF-1 receptor (global hemizygous knockout (IGFRKO) and endothelial cell specific IGF-1R knockout (ECIGFRKO)) evidence of increased basal NO production in the vasculature, with augmentation of this increase relative to decreasing IGF-1R number (WT v ECIGFRKO hemizygotes p=0.01, WT vs ECIGFRKO homozygotes p = 0.001). Furthermore, by decreasing IGF-1R numbers in the insulin resistant hemizygous insulin receptor knockout (IRKO) model (IRKO x IGFRKO) insulin sensitivity in the vasculature can be restored. In this study, we have investigated further these receptor interactions with the generation of a mouse overexpressing the human IGF-1R specifically in the endothelium under control of the Tie-2 promoter-enhancer (hIGFREO) and by targeted knockdown of the IGF-1R in human endothelial cells. ...
After oral administration MTX is rapidly but incompletely absorbed. Its bioavailability is about 70% at low doses (≤10 mg/m2), approximately 15-20% lower than that of intramuscular (IM) or intravenous (IV) MTX.4,5 In addition, there is a marked interindividual and a moderate intraindividual variability in the extent of absorption of oral MTX.6 Oral administration in doses above 25 mg/day is associated with lower bioavailability due to the saturation of the absorption mechanism. Thus in high doses the parenteral administration is mandatory.7 IM MTX showed higher bioavailability than oral MTX either as tablets or as solution.8 However, other studies have shown a similar MTX concentration after oral, IM, or IV administration.5,9. To compare the relative bioavailability of oral versus intramuscular administration in patients with RA, the pharmacokinetics of MTX at both the usual starting dose of 7.5 mg and at established higher maintenance doses was examined in 21 patients.10 Pharmacokinetics ...
When assessing the risks to children and adults due to contaminated soil and/or house dust, it has become clear over the past 25 years that ingestion does not equal the absorbed dose. That is, not all of the chemical in these media will be absorbed due to a myriad of chemical interactions with the different types of soil and dust present in the environment. To characterize the likely absorbed dose, many factors need to be considered. Theoretically, physiochemical characteristics should govern interactions between the contaminant and soil matrix and may affect solubilization, gastrointestinal absorption, and subsequently absolute oral bioavailability. Once solubilized and bioaccessible, a chemical must undergo absorption from the gut into systemic circulation. Absorption is most affected by chemical ionization, lipophilicity, and solubility. However, nearly 3 decades of research have not given sufficient insight to develop a universal model for predicting bioaccessibility. In this paper, we ...
Forte is utilization of the Maurmerization technology, providing more complete intake of the products ingredients.. Astymin Forte represents an encapsulated combination of 7 types of granules of different colors. Dissolution rate of each granule type is carefully calculated to allow the dissolution within the prescribed time and in certain regions of gastrointestinal tract. As a result the amino acids and vitamins, which can be found in Astymin Forte, are absorbed in the blood stream slowly and as much as possible, providing 98% bioavailability! So far, such a high bioavailability is completely unattainable for other amino acid and vitamin complexes!. Distribution of active ingredients in the granules of Astymin Forte furthermore provides a very short time to maximum blood amino acid concentration after the product administration - about 20-30 minutes.. As opposed to Astymin Forte most amino acid and vitamin complexes are manufactured in traditional presentation. Due to this active substances ...
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder. Although there is no established treatment for the core symptoms of ASD, recent research has indicated a potentially therapeutic effect of intranasally administered oxytocin. TTA-121 is a novel oxytocin nasal spray with high bioavailability and is expected to increase oxytocin delivery to the brain by adjusting osmolality and viscosity of the formulation. As nonclinical safety studies to support the conduct of the Phase 1 and Phase 2 studies of TTA-121, a 6-week repeated intranasal dose toxicity study of TTA-121 in rats was conducted. In the present study, TTA-121 was administered intranasally to male and female rats at 0 (placebo), 1.2, 6, and 30 U/body/day once daily for 6 weeks followed by a 4-week recovery period to evaluate potential toxicity and systemic exposure to oxytocin. The toxicokinetic analysis indicated that systemic exposure of oxytocin increased with a dose ranging from 1.2 to 30 U/body/day at the ...
Magnesium (glycinate) Magnesium (glycinate) is a highly bioavailable magnesium chelate, which supports the metabolism and utilization of carbohydrates, amino acids and fats for energy. Magnesium (glycinate) helps activate enzymes for physiological functions including cardiac health. Highly bioavailable magnesium chelat
Sigma-Aldrich offers abstracts and full-text articles by [Valeria Galetti, Prosper Kujinga, Comlan Evariste S Mitchikpè, Christophe Zeder, Fabian Tay, Félicien Tossou, Joseph D Hounhouigan, Michael B Zimmermann, Diego Moretti].
Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases ...
Vitamin stability has been studied for decades under a variety of storage conditions, and it is interesting to see how chemical manufacturers address long term stability issues. As stated on the website of DSM (a chemical company located in the Netherlands): The vitamin manufacturing industry has developed products of high purity and quality, with improved stability, high bioavailability and optimum handling and mixing properties…. However, when dealing with complex and reactive compounds such as the vitamins, no product form can offer complete and unlimited protection against destructive conditions, excessive periods of storage or severe manufacturing processes. The individual feed manufacturer must take responsibility for assuring customers that vitamins have been stored, handled and added to feeds in an optimum manner and that vitamin levels are routinely monitored for quality assurance.. Temperature, water content, pH, oxygen levels, light (type/intensity), catalysts (metals like Fe, Cu, ...
Organic PurePea™, an organic, natural pea protein isolate, offers a high level of functionality and nutritional benefits. Organic PurePea™ is a true vegan protein which has high bioavailability and excellent digestibility.* The raw materials, certified or
ALKOSELR397 is a specific inactivated whole cell yeast (Saccharomyces cerevisiae NCYC R397) product containing elevated levels of organic selenium (min. 98%).. It is registered and authorized in the European Union as a nutritional feed additive for all animal species (EC 3b8.11). It contains more than 98% of selenium in an organic form (this means the element selenium is metabolized by the yeast and part of the amino acids and proteins).. Due to its high bioavailability, ALKOSELR397 optimizes the animals selenium status, which helps realize their full growth and production potential. The product quality and consistency of ALKOSELR397 guarantees animal performance, which will, in turn, result in increased profitability.. ...
n humans, they are converted to acyclovir and penciclovir.This causes their close morphological and histological properties.. mechanism of action of acyclovir is in the interaction with enzymes of the virus, and then interrupted their development cycle.The result is the death of the microorganism.This interaction ensures the structure of acyclovir, which is similar to dezoksiguanedina (purine nucleoside).The most sensitive to this drug is the herpes simplex virus.There are strains of microorganisms which are resistant to this drug.This effect can be explained by the use of immunosuppressive therapy.The mechanism of resistance is a mutation of the virus enzyme systems, changing the specificity of the drug.In the event of such situations are drugs of other pharmacological groups (Foscarnet).Children antivirals include Valacyclovir.The high bioavailability, which is more than fifty percent causes a similar effect.This means that to achieve the effect required much smaller doses of the drug ...
Magnesium malate is a combination of magnesium molecules with malic acid. Magnesium malate is well tolerated and has a very high bioavailability. The exceptionally small particle size of magnesium and the fact that it is bound to malic acid guarantees
Some of the studies cited above simply used raw ginger powder to achieve the reported results, so this approach certainly has proven merit (and its nearly always the least expensive).. Simply brewing tea with ginger powder (or even mixing the powder into room temperature water) can provide relief from nausea, headaches, and other everyday maladies. Raw ginger root also adds a nice kick to smoothies and cooked dishes, so for an extra antioxidant and anti-inflammatory boost, throw some in whenever you think of it.. If you want to implement ginger as an acute therapeutic agent for the prevention and treatment of disease, though, its best to work with concentrated full-spectrum extracts and oils (especially those that have been optimally formulated for high bioavailability).. This product is our favorite, especially if youre seeking out ginger for any kind of pain relief-its a powerful complex of liposomal ginger oil, curcumin (the famed healing component in turmeric), and vegan DHA (which also ...
BUTYCAPS 900 mg Tributyrin (787 mg Butyric Acid) / sachet BUTYCAPS is a food supplement containing Microencapsulated Tributyrin.. Tributyrin is a triglyceride containing 3 molecules of butyric acid. It is a form of administration ensuring high bioavailability of butyric acid in all sections of the intestine.. Butyric acid has important actions for intestinal health, comprising both nutrition and trophism of the intestinal cells, such as favoring a balanced intestinal microbiota.. The microencapsulation technology of BUTYCAPS allows a slower and gradual release along the intestine.. BUTYCAPS are non-chewable granules.. Each sachet contains 900 mg of tributyrin microencapsulated, equivalent to 787 mg of butyric acid. Each box contains 30 sachets.. Recommended Dosage: 1 sachet per day. Other dosages may be followed after the advice of a healthcare professional.. How to Use: Open the sachet and add its content to a yogurt or to a pureed consistency food. It can also be poured directly into the mouth ...
DescriptionMaplelifes Collage peptide uses the hydrolyzed form of collagen, Peptan® collagen peptides. Peptan® is a type 1 collagen peptide that is identical to the collagens in human bones and skin. Collagen is an important type of protein that makes up the structural framework in the body. Vitamin C is an essential nutrient in supporting collagen synthesis. Biotin is an important B-vitamin for maintenance the health of your hair, skin, and nails. MapleLifes Collage peptide is scientifically designed formula to boost skin beauty, maintain healthy hair, nail, and immune function; maintain healthy bones, cartilage, teeth, and gum, and improve joint health.4 reasons to choose Maplelifes Collage peptide: Bioactive and easily digestible protein. Peptan® is a high-purity, natural bioactive product, containing more than 97% protein (on a dry weight basis). The hydrolyzed form of collagen contributes to the high bioavailability and activity of Peptan. Healthy aging. Joint degeneration and inflammation
TY - JOUR. T1 - Pharmacokinetics and bioavailability of digitoxin by a specific assay. AU - MacFarland, R. T.. AU - Marcus, F. I.. AU - Fenster, P. E.. AU - Graves, P. E.. AU - Perrier, D.. PY - 1984/1. Y1 - 1984/1. N2 - The pharmacokinetics and bioavailability of digitoxin were examined in six normal human subjects using an assay that separates digitoxin from its metabolites. After intravenous administration, the mean systemic clearance was 2.44 ml/min; the volume of distribution was 0.47 l/kg; and the elimination half-life was 6.5 days. After oral administration, the elimination half-life was 5.8 days. The bioavailability was 81.5% using the specific assay. Using a non-specific, direct serum digitoxin radioimmunoassay the bioavailability was 98.0%. Assay of aqueous fractions from extracted serum samples indicated higher levels of water-soluble metabolites following oral compared to intravenous digitoxin administration. These findings suggest that previously reported values for digitoxin ...
Bioavailable P is the proportion of P that can be absorbed and available for use or storage.4 The most common methods to estimate P bioavailability are the slope-ratio assay and digestibility experiments. The slope-ratio assay method theoretically estimates the digestible plus post-absorptive utilization of P at the tissue level and is known as available P (AvP), whereas digestibility experiments measure only digestible utilization, known as digestible P.5. Available P. In the slope-ratio assay method, linear regression is fitted to the response criterion (eg, growth performance or bone ash) for each set of titrated diets (new versus inorganic standard ingredient) and the slope of the equation from the ingredient is divided by the slope from the inorganic standard. The drawbacks of the slope-ratio assay method1,5 are mainly assumption that the inorganic standard is 100% bioavailable, thus it is important to use the same standard for all ingredients; dependence on the response criterion used ...
As far as the synergy, I would think that most would be already taking the CoQ-10, resveratrol, B-vitamins and green tea.. Curcumin-soy formulation may boost absorption 60-fold: Indena study - Nutra USA, 4/6/11 - Curcumin has been a sort of forbidden fruit for biomedical research, since its poor oral bioavailability has substantially hampered clinical development, despite the very promising indications of the preclinical research ... The volunteers received five (low-dose - 209 mg total curcuminoids) or nine (high-dose - 376 mg total curcuminoids) hard-shell capsules of either the soybean-based phospholipid-curcumin formulation (Meriva) or five capsules of a non-formulated curcuminoid mixture containing 1799 mg of curcuminoids ... Total curcuminoid absorption was about 29-fold higher for Meriva than for its corresponding unformulated curcuminoid mixture, but only phase-2 metabolites could be detected, and plasma concentrations were still significantly lower than those required for the ...
US Department of Health and Human Service, FDA Center for Drug Evaluation and Research (CDER) Draft Guidance: Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate Release Solid Dosage Forms Containing Certain Active Moieties/Active Ingredients Based on a Biopharmaceutic Drug Classification System. CDERGUID-2062 DFT.WPD, January 1999. ...
"Generic Adderall Availability". Drugs.com. Retrieved 6 February 2020. "Generic Adderall XR Availability". Drugs.com. Retrieved ... For one, it helps us redefine what a biological individual is. We suggest that a human individual is now best described as a ... Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability ... Stereochemical course of the reaction" (PDF). Journal of Biological Chemistry. 249 (2): 454-458. PMID 4809526. Retrieved 6 ...
"Nonproprietary Naming of Biological Products; Draft Guidance for Industry; Availability". U.S. Food and Drug Administration ( ... A version of the four-letter suffix has been proposed to the WHO as the biological qualifie" (BQ). It is not part of the INN, ... Even though the biosimilars market is rising, the price drop for biological drugs at risk of patent expiration will not be as ... A biosimilar is not regarded as a generic of a biological medicine. This is mostly because the natural variability and more ...
Biological functions[edit]. The cysteine sulfhydryl group is nucleophilic and easily oxidized. The reactivity is enhanced when ... The systemic availability of oral glutathione (GSH) is negligible; so it must be biosynthesized from its constituent amino ... the sulfhydryl group of cysteine has numerous biological functions, and cysteine may have played an important role in the ...
Biological functions[edit]. The cysteine sulfhydryl group is nucleophilic and easily oxidized. The reactivity is enhanced when ... The systemic availability of oral glutathione (GSH) is negligible; so it must be biosynthesized from its constituent amino ... Glutamic acid and glycine are readily available in most Western diets, but the availability of cysteine can be the limiting ... the sulfhydryl group of cysteine has numerous biological functions, and cysteine may have played an important role in the ...
"Food availability and daily biological rhythms". Neuroscience & Biobehavioral Reviews. 4 (2): 119-131. 1980-06-01. doi:10.1016/ ... Journal of biological rhythms. 33 (5): 458-474. doi:10.1177/0748730418789043. ISSN 0748-7304. PMC 6693510. PMID 30033846. ... Journal of Biological Rhythms. 33 (5): 458-474. doi:10.1177/0748730418789043. PMC 6693510. PMID 30033846. Mieda, Michihiro; ...
Biological Conservation. 71: 61-67. doi:10.1016/0006-3207(94)00021-H. Archived from the original (PDF) on 2012-10-12.. ... Estany-Tigerström, David; Bas, Josep Maria; Pons, Pere (2010). "Does Argentine ant invasion affect prey availability for ... foliage-gleaning birds?". Biological Invasions. 12 (4): 827-839. doi:10.1007/s10530-009-9504-6.. ...
... , like other biological stains may be certified by the Biological Stain Commission signifying that a particular ... Lillie RD (1974). "The hematoxylin shortage and the availability of synthetic substitutes". Am J Med Technol. 40 (11): 455-61. ... Lillie, Ralph Dougall (1977). H. J. Conn's Biological stains (9th ed.). Baltimore: Williams & Wilkins. pp. 692p. Mitchell, A. ( ... Schulte EK (1991). "Standardization of biological dyes and stains: pitfalls and possibilities". Histochemistry. 95 (4): 319-28 ...
Robert C. Ramger (February 1966). "The Availability of Helminth Parasites in Biological Supply Houses". The American Biology ...
Their biological availability to the body depends upon dihydrofolate reductase action in the liver. This action is unusually ... Biological roles[edit]. The formation of tetrahydrofolate (FH4, also THF) begins when folic acid (F) is reduced to ... All the biological functions of folic acid are performed by tetrahydrofolate and other derivatives. ... despite the availability of folate in foods and in supplements, there was still a challenge for people to meet their daily ...
Biological role and precautions[edit]. This section needs expansion. You can help by adding to it. (January 2013) ... Radium has a low availability and is highly radioactive, making it toxic to life. ... Beryllium's low aqueous solubility means it is rarely available to biological systems; it has no known role in living organisms ...
Federal Register Notice of Availability recovery plan.) PDF. (Page revised December 19, 2007). Endangered Species - Tumbling ... Proceedings of the Biological Society of Washington 103(l): 197-204. PDF. Wooley C. M. (September 22, 2003). "Approved Recovery ...
One hundred years of Biology Biological Bulletin Volume 168 Number 3 Symposium Supplement to the Biological Bulletin [4] Free ... Dohrn argued that availability of all the major published sources was essential. He gave his own books and scientific journals ... The Naples Station's biological reference collection is still unrivalled in Europe today.[citation needed] The first librarian ... SZN was divided into five parts: Biological Oceanography, Benthic Ecology (at the Villa Dohrn in Ischia), Biochemistry, Cell ...
"Habitat selection of the Eurasian woodcock in winter in relation to earthworms availability". Biological Conservation. 122 (3 ... Biological Conservation. 122 (1): 89-97. doi:10.1016/j.biocon.2004.07.002. "BTO/Game Conservancy Trust Breeding Woodcock Survey ...
Schaefer, M. R.; Golden, S. S. (1989-05-05). "Light availability influences the ratio of two forms of D1 in cyanobacterial ... Biological Sciences. 357 (1426): 1369-1420. doi:10.1098/rstb.2002.1134. ISSN 0962-8436. PMC 1693055. PMID 12437876. ... thylakoids". Journal of Biological Chemistry. 264 (13): 7412-7417. ISSN 0021-9258. PMID 2496127. http://www.nasonline.org, ...
When there is less food available, feeding adjusts to rates that correlate with food availability. In a study of A. tonsa in ... Miller, Charles (2004). Biological Oceaonography. Oxford: Blackwell. pp. 162, 176. ISBN 0-632-05536-7. Durbin, Ann (December 15 ... not related to light availability, but persistent regardless of whether the copepods were subjected to light or dark. This ... 1990). "Diel feeding behavior in the marine copepod Acartia tonsa in relation to food availability". Marine Ecology Progress ...
Radium has a low availability and is highly radioactive, making it toxic to life. The next alkaline earth metal after radium is ... Beryllium's low aqueous solubility means it is rarely available to biological systems; it has no known role in living organisms ...
The first known biological control of privet is the privet lace bug (Leptoypha hospita), which has been deployed in New Zealand ... on Decomposition and Nutrient Availability in Riparian Forests. Invasive Plant Science and Management 4:437-447. Bradley, B.A ... Biological Invasions. 14:139-150 Zhang, Y., Hanula, J., Horn, S., Braman, S.K., Sun, J. (2011). Biology of ''Leptoypha hospita ... Biological species invasion is considered a main component of global ecosystem change due to changes in biogeochemical cycles ...
"Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis". Biological Psychiatry ... The central thesis is, that harm reduction is not only a social concept, but also a biological one. More specifically, ... In addition to this, antagonists of mammalian CB receptors was seen to block both of the biological activities previously ... The Journal of Biological Chemistry. 279 (7): 5298-305. doi:10.1074/jbc.M306642200. PMID 14634025. Devane WA, Hanus L, Breuer A ...
The systemic availability of oral glutathione (GSH) is negligible; so it must be biosynthesized from its constituent amino ... Because of its high reactivity, the sulfhydryl group of cysteine has numerous biological functions. Due to the ability of ...
Biological Reviews of the Cambridge Philosophical Society, 58, 521-561. Keddy, P. A., Campbell, D., McFalls T., Shaffer, G., ... Physical alterations include changes in water temperature, water flow and light availability. Chemical alterations include ... Biological alterations include over-harvesting of commercial species and the introduction of exotic species. Human populations ... A stress on an aquatic ecosystem can be a result of physical, chemical or biological alterations to the environment. ...
... orchestrators of TGF-beta availability". The Journal of Biological Chemistry. 280 (9): 7409-12. doi:10.1074/jbc.R400029200. ... The Journal of Biological Chemistry. 275 (49): 38363-70. doi:10.1074/jbc.M004861200. PMID 10995749. Arsura M, Wu M, Sonenshein ... The Journal of Biological Chemistry. 270 (18): 10618-24. doi:10.1074/jbc.270.18.10618. PMID 7737999. Annes JP, Munger JS, ... Biological Psychiatry. 68 (10): 930-41. doi:10.1016/j.biopsych.2010.06.012. PMID 20692646. S2CID 6544784. Senatorov VV, ...
The availability of these things will affect the cost benefits of the body deploying its own biological ones. This could, in ... Now, if you wonder about this choice of managerial terminology for talking about biological healing systems, I should say that ... Placebos are explained as the result of false information about the availability of external treatment and support that mislead ... External treatment and the availability of support is factored into the health management system's cost-benefit assessment as ...
Nectar availability is likely to influence Karner blue butterfly abundance. In a right-of-way in west-central Wisconsin, the ... Schellhorn, Nancy A.; Lane, Cynthia P.; Olson, Dawn M. (2005). "The co-occurrence of an introduced biological control agent ( ... Report to National Biological Survey and U. S. Fish and Wildlife Service. Baraboo, WI: North American Butterfly Association.. ... Grundel, R; Pavlovic, N (2007). "Resource availability, matrix quality, microclimate, and spatial pattern as predictors of ...
He was also able to visit the Marine Biological Laboratory in Massachusetts. Bertalanffy was still in the US when he heard of ... The ultimate length equals the maximum length at high food availabilities. The Bertalanffy equation is the equation that ... In English: Problems of Life: An Evaluation of Modern Biological and Scientific Thought, New York: Harper, 1952. 1953, ... Peter Corning (2001). Fulfilling von Bertalanffy's Vision: The Synergism Hypothesis as a General Theory of Biological and ...
3.1 Water quality and availability 3.2 Structural safety of project infrastructure 3.3 Life and fire safety (L&FS) ... 2.5 Biological hazards 2.6 Radiological hazards 2.7 Personal protective equipment (PPE) 2.8 Special hazard environments ...
"Availability of new Bayesian-delimited gecko names and the importance of character-based species descriptions". Proceedings of ... the Royal Society B: Biological Sciences. 278 (1705): 490-492. doi:10.1098/rspb.2010.1330. PMC 3025678. PMID 20961901. ...
"Availability of new Bayesian-delimited gecko names and the importance of character-based species descriptions." Proceedings of ... the Royal Society of London B: Biological Sciences (2010): rspb20101330. Eniang, E. A., and H. M. Ijeomah. "Diversity of ...
In W. R. Wolf (ed.), Biological Reference Materials: Availability, uses and need for validation of nutrient measurement, pp. 3- ... Bowen, H. J. M., A standard biological material for elementary analysis. In P. W. Sallis (ed.), Proc. of the SAC Conference, ... Stoeppler, M., Wolf, W. R. and Jenks, P. J. (eds.), Reference Materials for Chemical Analysis: Certification, Availability and ...
"Rectal administration of nicomorphine in patients improves biological availability of morphine and its glucuronide conjugates ...
Biological Bulletin, 218(3): 211-229. Mérot, Claire; Collin, Rachel. 2012. Effects of food availability on sex change in two ... Biological Journal of the Linnean Society, 4: 541-593 Henry, Jonathan J.; Collin, Rachel; Perry, Kimberly J.. 2010. The Slipper ... Biological Journal of the Linnean Society, 4: 541-593 Collin, R. 2003. Phylogenetic Relationships Among Calyptraeid Gastropods ...
Humphries, M. M.; Thomas, D.W.; Kramer, D.L. (2003). "The role of energy availability in mammalian hibernation: A cost-benefit ... Those species that seek pest insects are considered beneficial 'biological control agents' and their presence encouraged in ... biological pest control programmes.[45] Combined, insectivorous birds eat 400-500 million metric tons of arthropods annually.[ ...
Resulting information can be used to build biological models, design experiments, or get up to speed in an area of research. ... BD Cell Pathways "Ingenuity Systems Announces Immediate Availability Of The Ingenuity Pathways Knowledge Base" (Press release ... All QIAGEN Silicon Valley use the Ingenuity Knowledge Base, which contains biological and chemical interactions and functional ... to analyze complex biological systems. QIAGEN Silicon Valley's first product, IPA, was introduced in 2003, and is used to help ...
Biological chemistryEdit. Group 3 elements are generally hard metals with low aqueous solubility, and have low availability to ... Lutetium has no biological role as well, but it is found even in the highest known organism, the humans, concentrating in bones ... Scandium has no biological role, but it is found in living organisms. Once reached a human, scandium concentrates in the liver ... Yttrium has no known biological role, though it is found in most, if not all, organisms and tends to concentrate in the liver, ...
A Vital Legacy: Biological and Environmental Research in the Atomic Age, U.S. Department of Energy, The Office of Biological ... The advantage of FDG-PET for these uses is its much wider availability. Some radioactive tracers used for Alzheimer's are ... Psychiatry: Numerous compounds that bind selectively to neuroreceptors of interest in biological psychiatry have been ...
"Proceedings of the Royal Society B: Biological Sciences. 276 (1654): 121-127. doi:10.1098/rspb.2008.0858. PMC 2614250. PMID ... "Influence of light availability on leaf structure and growth of two Eucalyptus globulus ssp. globulus provenances" (PDF). Tree ...
May 2002). "Hemorrhagic fever viruses as biological weapons: medical and public health management". Journal of the American ... This damage occurs due to the synthesis of Ebola virus glycoprotein (GP), which reduces the availability of specific integrins ... It has the potential to be weaponised for use in biological warfare,[226][227] and was investigated by Biopreparat for such use ...
"Biological Journal of the Linnean Society. 77 (2): 193-200. doi:10.1046/j.1095-8312.2002.00096.x. ISSN 0024-4066.. ... Availability of mallards, mallard ducklings, and fertilised mallard eggs for public sale and private ownership, either as ... nutrient availability, and interspecific and intraspecific competition.[62] The majority of the mallard's diet seems to be made ... where they are rare but increasing in availability.[35] ...
With this increase in population and availability of labor came an increase in labor specialization.[36] What triggered the ... including the possibility of the permanent alteration of our biological nature. These concerns are shared by other philosophers ... The advancements in technology in this era allowed a more steady supply of food, followed by the wider availability of consumer ...
Medical availability and clinical practice varies across the world due to regional differences in culture and technology. ... Biomechanics is the study of the structure and function of biological systems by means of the methods of Mechanics. ... Biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. ... Histology is the study of the structures of biological tissues by light microscopy, electron microscopy and ...
DeMarse TB, Wagenaar DA, Blau AW, Potter SM (2001). "The Neurally Controlled Animat: Biological Brains Acting with Simulated ... Because of their wide availability, neuronal networks are typically cultured from dissociated rat neurons. Studies commonly ... The Centre for Excellence in Biological Art, at the University of Western Australia. Another example can be seen in the ...
"Proceedings of the Royal Society B: Biological Sciences. 278 (1708): 1090-1097. doi:10.1098/rspb.2010.1579. PMC 3049027. PMID ... Given that phosphorus availability is thought to limit productivity in much of the region, the decrease in its transport from ... "Secretariat of the Convention on Biological Diversity. Retrieved 9 January 2017.. *^ Glowka, Lyle; Burhenne-Guilmin, Françoise ... We have driven the rate of biological extinction, the permanent loss of species, up several hundred times beyond its historical ...
Lithium naturally only occurs in traces in biological systems and has no known biological role, but does have effects on the ... and availability in significant amounts of several micrograms,[40] to make a large enough target to increase the sensitivity of ... Biological role and precautionsEdit. MetalsEdit. Pure alkali metals are dangerously reactive with air and water and must be ... Rubidium has no known biological role, but may help stimulate metabolism,[234][235][236] and, similarly to caesium,[234][237] ...
... is the manner in which a biological taxon is spatially arranged. Species distribution is not to be ... Distribution patterns can change seasonally, in response to the availability of resources, and also depending on the scale at ... and social factors include land use and water availability. An example of the effects of abiotic factors on species ...
"FHTET Biological Control Program-Sponsored Projects" (PDF). FHTET Biological Control Program. USDA Forest Service. Retrieved 10 ... high temperature and low nitrate availability.[16] Brassicaceae contain different cocktails of dozens of glucosinolates. They ... Oxford biological.. *^ Martin, N. A. (2004-01-01). "History of an invader, Scaptomyza flava (Fallen, 1823) (Diptera: ... Given that not one of an estimated 76 species that prey on the plant has been approved for biological control in North America ...
Biological Reviews. 78 (2): 251-345. doi:10.1017/S1464793102006103. PMID 12803423.. *^ a b Sahney, S., Benton, M.J. & Falcon- ... food requirements and adaptive metabolisms allow reptiles to dominate the animal life in regions where net calorie availability ... "Proceedings of the Royal Society B: Biological Sciences. 274 (1610): 635-640. doi:10.1098/rspb.2006.3763. PMC 2197205. PMID ... Biological and Biomedical Sciences. 39 (3): 298-313. doi:10.1016/j.shpsc.2008.06.004. PMID 18761282.. ...
The table below shows historical and predicted regional population figures in millions.[105][106][107] The availability of ... "Biological annihilation via the ongoing sixth mass extinction signaled by vertebrate population losses and declines". PNAS ...
"Proceedings of the Royal Society B: Biological Sciences. 277 (1681): 651-659. doi:10.1098/rspb.2009.1615. PMC 2842690. PMID ... As an example of ecological availability, chimps may learn how to fish for ants with a stick from their peers, but that ... "Philosophical Transactions of the Royal Society B: Biological Sciences. 366 (1567): 969-977. doi:10.1098/rstb.2010.0343. PMC ... "Philosophical Transactions of the Royal Society B: Biological Sciences. 369 (1644): 20130420. doi:10.1098/rstb.2013.0420. PMC ...
"Journal of Biological Chemistry. 146: 85-93.. *^ Berg, Jeremy M.; Tymoczko, John L.; Stryer, Lubert (2002). "Appendix: Vmax and ... In that case, the substrate will reduce the availability for an inhibitor to bind, and, thus, outcompete the inhibitor in ... Biological Examples[edit]. After an accidental ingestion of a contaminated opioid drug desmethylprodine, the neurotoxic effect ...
Management of Biological Invasions. 7 (4): 321-328. doi:10.3391/mbi.2016.7.4.02. ISSN 1989-8649.. ... The latter result may be a side-effect of invasives' ability to capitalize on increased resource availability and weaker ... Van Driesche, Jason; Roy Van Driesche (2004). Nature Out of Place: Biological Invasions In The Global Age. Island Press. p. 377 ... Williams, J.D.; G. K. Meffe (1998). "Non indigenous Species". Status and Trends of the Nation's Biological Resources. Reston, ...
"Philosophical Transactions of the Royal Society B: Biological Sciences. 361 (1465): 23-43. doi:10.1098/rstb.2005.1736. PMC ... In the larger species of parrots and cockatoos, the availability of nesting hollows may be limited, leading to intense ... "The Institute for Biological Invasions. Archived from the original on 2007-07-01.. ... Oren, David C.; Novaes, Fernando (1986). "Observations on the golden parakeet Aratinga guarouba in Northern Brazil". Biological ...
Biological Conservation, 143(3), 710-721. *^ a b c d e Love, J. A. (1988). The reintroduction of the white-tailed sea eagle to ... wintering in northern Arizona select perches based on food availability, visibility and cover (Doctoral dissertation, Northern ... Biological Conservation, 4(5), 373-377. *^ Kalisńska, E., Salicki, W., & Jackowski, A. (2006). Six Trace Metals in White-Tailed ... Biological Conservation, 145(1), 79-85. *^ Dahl, E. L., May, R., Hoel, P. L., Bevanger, K., Pedersen, H. C., Røskaft, E., & ...
"Biological Altruism". Stanford Encyclopedia of Philosophy. Retrieved 13 May 2011.. *^ Trivers, R.L. (1971). "The evolution of ... of resource availability and the abilities needed to gather resources. This may signal to others that the altruist is a ... Altruism in biological observations in field populations of the day organisms can be defined as an individual performing an ...
... and the availability of practical reasoning algorithms. OWL DL includes all OWL language constructs, but they can be used only ... only mean biological parent or mother and not social parent or mother. ...
"Proceedings of the Royal Society B: Biological Sciences. 283 (1841): 20161762. doi:10.1098/rspb.2016.1762. ISSN 0962-8452. PMC ... but they will range more widely where food availability is lower. It is difficult to determine the extent of their home range ... psychological and other biological experiments, and constitute an important model organism. This is because they grow quickly ... rats used as model organisms in biological research. ...
I. Isolation and characterization of the protein-glycogen complex". Journal of Biological Chemistry. 245 (24): 6642-6648. PMID ... The increased calcium availability binds to the calmodulin subunit and activates glycogen phosphorylase kinase. Glycogen ... Upon eating a meal, there is a release of insulin, signaling glucose availability in the blood. Insulin indirectly activates PP ... Browner MF, Fletterick RJ (February 1992). "Phosphorylase: a biological transducer". Trends in Biochemical Sciences. 17 (2): 66 ...
The new literate population was due to a high rise in the availability of food. This enabled many people to rise out of poverty ... the development of biological taxonomy; a new understanding of magnetism and electricity; and the maturation of chemistry as a ...
A possible biological basis for the case reports of depression involves decreased metabolism in the orbitofrontal cortex (OFC) ... restrictions on its more immediate availability have proved contentious.[17] In New Zealand, isotretinoin can be prescribed by ... Roche decided to discontinue manufacturing due to diminishing market share due to the availability of the many generic versions ... Studies have uncovered several biological processes which may credibly explain the affective changes induced by isotretinoin. ...
The development of the silicon transistor and its first commercial availability in 1956 was the pivotal event which led to ... Biological pacemaker. *Button cell. *Electrical conduction system of the heart. *Implantable cardioverter-defibrillator ... Some devices have the availability to display intracardiac electrograms of the onset of the event as well as the event itself. ... though will vary depending upon patient/device status and remote monitoring availability. Newer pacemaker models can also be ...
"Renewable biological systems for alternative sustainable energy production (FAO Agricultural Services Bulletin - 128)". Final ... 8 Availability and prices. *9 Production *9.1 Production levels. *9.2 Biodiesel feedstocks *9.2.1 Quantity of feedstocks ...
Proceedings of the Royal Society B: Biological Sciences. 276 (1676): 4087-4094. doi:10.1098/rspb.2009.1339. PMC 2821352. PMID ... Key factors that affect seasonal reproduction include the length of the wet season, subsequent food availability, and the ... A sample of strepsirrhine diversity; eight biological genera are depicted (from top, left to right): Lemur, Propithecus, ...
Biological context of Biological Availability. *Despite increasing attempts to control environmental pollution, changes in the ... Disease relevance of Biological Availability. *Ritonavir is an inhibitor of HIV-1 protease with potent in vitro anti-HIV ... Associations of Biological Availability with chemical compounds. *To assess the potential for therapeutic problems related to ... High impact information on Biological Availability. *This suggests a defect in the gene HSD11B1 encoding 11beta-hydroxysteroid ...
Biological availability of sediment phosphorus inputs to the lower Great Lakes. [Scott C Martin; Joseph V DePinto; Thomas C ... Biological availability of sediment phosphorus inputs to the lower Great Lakes. Author:. Scott C Martin; Joseph V DePinto; ... schema:name "Biological availability of sediment phosphorus inputs to the lower Great Lakes"@en ;. schema:productID "15358557 ... Add tags for "Biological availability of sediment phosphorus inputs to the lower Great Lakes". Be the first. ...
Availability of an Environmental Assessment for a Biological Control Agent for Old World Climbing Fern. A Notice by the Animal ... Notice of availability and request for comments. SUMMARY:. We are advising the public that the Animal and Plant Health ... for the biological control (biocontrol) of Old World climbing fern in Florida. The purpose of the proposed release is to reduce ... for the biological control of Old World climbing fern in Florida. We are making the environmental assessment available to the ...
1986 Food availability affects growth in a coral reef fish. Oecologia 70, 136-139. (doi:10.1007/BF00377123). ... To summarize, resource availability leads to a considerably plastic response by strongly affecting life-history traits when ... 2010 Dietary carotenoid availability, sexual signalling and functional fertility in sticklebacks. Biol. Lett. 6, 191-193. (doi: ... Your Name) thought you would like to see the Proceedings of the Royal Society of London B: Biological Sciences web site. ...
General Considerations for Pediatric Pharmacokinetic Studies for Drugs and Biological Products. This document is intended to ... is announcing the availability of a draft guidance for industry entitled `` ... Availability. A Notice by the Food and Drug Administration on 11/30/1998. ... Draft Guidance for Industry on General Considerations for Pediatric Pharmacokinetic Studies for Drugs and Biological Products; ...
ETDEWEB / Search Results / Influence of tensides and lipophilic substrates on the biological availability of polycyclic ... Influence of tensides and lipophilic substrates on the biological availability of polycyclic aromatic hydrocarbons (PAHs); ... "Influence of tensides and lipophilic substrates on the biological availability of polycyclic aromatic hydrocarbons (PAHs); ... title = {Influence of tensides and lipophilic substrates on the biological availability of polycyclic aromatic hydrocarbons ( ...
Vanguard Biological and Environmental Sample Materials NOT-HD-20-018. NICHD ... Notice of Availability of National Childrens Study (NCS) ... Notice of Availability of National Children s Study (NCS) ... It collected more than 14 million records and nearly 19,000 biological and 5,500 environmental primary samples from which a ... NICHD is issuing this Notice to alert interested investigators to the availability of biospecimens and environmental sample ...
"Biological Availability" by people in this website by year, and whether "Biological Availability" was a major or minor topic of ... "Biological Availability" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Biological Availability" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Biological Availability". ...
Silicon, aluminium and the biological availability of phosphorus in algae Message Subject (Your Name) has sent you a message ... Silicon, aluminium and the biological availability of phosphorus in algae. Christopher Exley, Alan Tollervey, Gillian Gray, ... Silicon, aluminium and the biological availability of phosphorus in algae. Christopher Exley, Alan Tollervey, Gillian Gray, ... Your Name) thought you would like to see the Proceedings of the Royal Society of London B: Biological Sciences web site. ...
Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [ ... Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [ ...
However, the formal detection and attribution of biological responses to climate change is associated with many challenges. We ... We discuss whether formal detection and/or attribution is necessary and suggest ways in which understanding of biological ... more extreme biological responses are being reported, and there is widespread interest in attributing such responses to ... to attribute these responses to anthropogenic climate change is limited by high natural variability in climate and biological ...
Funding availability. All students admitted to the Department of Biological Sciences, who do not hold a major scholarship, will ... Biological Sciences - Graduate Studies Biological Sciences Building 186. 2500 University Drive NW. Calgary, ABT2N 1N4. 403-220- ... Biological Sciences. Doctor of Philosophy (PhD). Toggle Compare Add degree to comparison list ... Graduate study in Biological Sciences puts students on the front lines of discovery. Doctoral students design, conduct and ...
Course Availability We will endeavour to make all course options available; however, these may be subject to timetabling and ... Frontiers in Biological Sciences (BI1009) - 15 Credit Points Eleven themes, critical to our understanding of the living world ... Biological Enhanced Skills Training (BEST) (BI2018) - 15 Credit Points The course will help you consolidate and develop skills ... Statistical Analysis of Biological Data (BI3010) - 15 Credit Points Review of basics of probability theory, data exploration ...
Funding availability. All students admitted to the Department of Biological Sciences, who do not hold a major scholarship, will ... Biological Sciences - Graduate Studies Biological Sciences Building 186. 2500 University Drive NW. Calgary, ABT2N 1N4. 403-220- ... Biological Sciences. Master of Science (MSc). Toggle Compare Add degree to comparison list ... Find new ways to pursue your passion for life in the University of Calgarys Biological Sciences department. Masters students ...
In the work underlying this thesis the availability, chemical composition and biological effects of PAHs in samples of soils ... Characterization of PAH-contaminated soils focusing on availability, chemical composition and biological effects ... The availability and bioavailability of contaminants in soil also has to be studied further, and such future studies should ... However, the link between the chemical analyses and the biological tests could be improved as as an organic solvent that ...
AVAILABILITY AND IMPLEMENTATION: The prototype implementation of the algorithm will be available upon request for non- ... YOABS: yet other aligner of biological sequences--an efficient linearly scaling nucleotide aligner.. Galinsky VL1. ... that combines the advantages of both hash and trie-based methods has been designed to effectively align long biological ...
AVAILABILITY AND IMPLEMENTATION: DA 1.0 was developed using Java and thus would be executable on any platform installed with ... DA 1.0: parameter estimation of biological pathways using data assimilation approach.. Koh CH1, Nagasaki M, Saito A, Wong L, ...
Data Availability. Crystallographic data for the structures reported in this manuscript have been deposited in the Cambridge ... Crystal Structure and Biological Evaluation of Two Novel Organic-Inorganic Hybrid Materials as Antitumor Agents in the ... Despite remarkable progress in the evolution of biological medicine field and understanding of the origin of the de diseases, ... cancer cells used in this work were commercially available from the Beijing National Institute for the Control of Biological ...
... polymeric and biological) materials, to hybrid materials or nanocomposites. ... Data Availability. The data obtained for this study are presented in the tables and figures herein. In addition, you may ... Biological Effects of Plasma-Based Graphene Oxide Deposition on Titanium. Keonho Rho,1 Chan Park,2 Khurshed Alam,1 Dongyun Kim, ...
Background Understanding the dynamical behaviour of biological systems is challenged by their large number of components and ... Availability of data and materials. All data generated or analysed during this study are included in the published article and ... In models of biological networks, these processes appear in a linear additive manner in each ODE. We first identify the ... Dynamical systems Biological networks Process analysis Model reduction Parameter sensitivity analysis Circadian clock ...
f) Crediting and availability of fees. (1) In general. Subject to paragraph (2), fees authorized under subsection (a) shall be ... 4) Biosimilar biological product fee. (A) In general. Each person who is named as the applicant in a biosimilar biological ... B) Annual biosimilar biological product development fee. (i) In general. A person that pays an initial biosimilar biological ... 1) Biosimilar biological product development program fees. (A) Initial biosimilar biological product development fee. (i) In ...
Availability. Building Blocks of Science 3D Spanish resources are available and accessible online at no additional charge to ... Biological Media & Supplies. Vast selection of ready to use biological media to meet diverse needs. In stock and ready to ship! ... "Carolina Biological knows that teachers have their hands full as they work hard every day to meet rigorous NGSS standards and ... Carolina Biological Supply Company. From its beginnings in 1927, Carolina (www.carolina.com) has grown to become the leading ...
Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to ... To get the biological information for each node, the node identifier is connected with the corresponding key identifier in the ... Valuable biological information can be highlighted on the nodes in the network, by the integration of various databases within ... The addition of biological information, such as pathway or disease association, helps to further understand the role of ...
MRPC learns a causal biological network efficiently and robustly from integrating individual-level genotype and molecular ... MRPC learns a causal biological network efficiently and robustly from integrating individual-level genotype and molecular ... Data Availability. Publicly available datasets were analyzed in this study. This data can be found here: GTEx: https://www. ... Learning Causal Biological Networks With the Principle of Mendelian Randomization. Md. Bahadur Badsha* and Audrey Qiuyan Fu* ...
This work is the first report of biological synthesis of CdS/CdSe Core/Shell QDs using bacterial cells and represents a ... As expected, the efficiency of solar cells sensitized with biological CdS/CdSe QDs increased almost 2.5 times when compared to ... This work is the first report of biological synthesis of CdS/CdSe Core/Shell QDs using bacterial cells and rep... ... As expected, the efficiency of solar cells sensitized with biological CdS/CdSe QDs increased almost 2.5 times when compared to ...
Software availability. The source code for Flowtrace is available for Fiji, ImageJ, Python 2, Python 3 and MATLAB. The full ... Flowtrace: simple visualization of coherent structures in biological fluid flows Message Subject (Your Name) has sent you a ... Flowtrace: simple visualization of coherent structures in biological fluid flows. William Gilpin, Vivek N. Prakash, Manu ... Flowtrace: simple visualization of coherent structures in biological fluid flows. William Gilpin, Vivek N. Prakash, Manu ...
This module explores a broad range of advanced topics in modern biological sciences, from evolution to cell and molecular ... Future availability. Biological science: from genes to species starts once a year - in October. This page describes the module ... Biological science: from genes to species. This module explores a range of advanced topics in biological science from evolution ... This topic takes a look at fascinating biological processes that occur at the beginning and end of the life of a cell. Cell ...
With massive increases in the availability of ecological and other kinds of biological data, skill in developing models to ... The University reserves the right to amend or remove courses and unit availabilities, as appropriate. ... is fundamental in modern biological research. This unit builds on the foundation provided in Quantitative Methods in Biology to ...
BIOL1004 - Biological Chemistry and Human Metabolism (2021) updated 10:35 AM on Thu, 15 April ... describe the physical and chemical characteristics of major classes of biological molecules. ... describe the physical and chemical characteristics of major classes of biological molecules ... Availabilities:. Location. Domestic. International. Gold Coast. Session2. Session2. Lismore. Session2 ...
This certificate program, offered through the Department of Biological Sciences, will prepare you to compete for jobs with ... Campus Availability Tab Closed. University Requirements Accordion Open. University Requirements. *. *. To receive an ...
  • Thank you for your interest in spreading the word on Proceedings of the Royal Society of London B: Biological Sciences. (royalsocietypublishing.org)
  • Message Body (Your Name) thought you would like to see the Proceedings of the Royal Society of London B: Biological Sciences web site. (royalsocietypublishing.org)
  • Graduate study in Biological Sciences puts students on the front lines of discovery. (ucalgary.ca)
  • A PhD in biological sciences is usually considered a final degree. (ucalgary.ca)
  • Find new ways to pursue your passion for life in the University of Calgary's Biological Sciences department. (ucalgary.ca)
  • A master's degree in biological sciences will give you the pre-requisite for a PhD. (ucalgary.ca)
  • The zebrafish facility within the School of Biological and Chemical Sciences at QMUL is dedicated to the maintenance of wild type, mutant and transgenic stock lines (for available lines please contact facility manager). (qmul.ac.uk)
  • The biological sciences encompass numerous cutting-edge disciplines, with each offering a multitude of exciting career paths. (nau.edu)
  • Our Master of Science program helps you move further down one of those paths by training you in the biological sciences through coursework and research experience. (nau.edu)
  • The Biology M.S. program prepares students for research-focused professions in the biological sciences, emphasizing the development of a students' ability to develop experimental approaches that accurately capture information to solve questions and problems in their biological field of study. (nau.edu)
  • Geneticists study these processes in all types of organisms and discover how errors in them can cause disease, and they help discover how genes work across the biological sciences. (le.ac.uk)
  • By studying genetics alongside options in other biological sciences, you will be able to apply your knowledge across the boundaries of traditional disciplines and gain a valuable and powerful asset in scientific environments and in many other walks of life. (le.ac.uk)
  • The first three years of this course are identical to the Biological Sciences (Genetics) BSc , including the option to spend a Year in Industry or a Year Abroad between Years 2 and 3. (le.ac.uk)
  • The analytical and critical skills you acquire by studying an MBiolSci in Biological Sciences are particularly valued by PhD supervisors, researchers and employers in non-scientific fields. (le.ac.uk)
  • In addition, students become qualified to pursue graduate studies in any of several areas of study within the Biological Sciences and the health professions. (wiu.edu)
  • Mathematical modelling has been used for decades as an approach to understand the functioning of biological systems in terms of their internal processes and components. (springer.com)
  • Complexity arises from the high dimension of the networks, the large number of biological processes involved and their non linearity due to the complex feedback loops that regulate them. (springer.com)
  • Reduction approaches have proven successful to significantly reduce model complexity, but they do not provide a mean to understand how the system dynamics emerges from the cascade of biological processes and regulatory mechanisms at work. (springer.com)
  • However, it is well known that these changes in biological processes are not static but dynamic. (springer.com)
  • You will learn about biological processes operating at different levels - molecular, cellular, organismal and species - and explore key concepts and research methodologies in these areas. (open.ac.uk)
  • Complex diseases are characterized by multiple subtle perturbations to biological processes. (biomedcentral.com)
  • We developed Mergeomics, a computational pipeline consisting of independent modules that 1) leverage multi-omics association data to identify biological processes that are perturbed in disease, and 2) overlay the disease-associated processes onto molecular interaction networks to pinpoint hubs as potential key regulators. (biomedcentral.com)
  • You will also gain a broad understanding of fundamental biological processes, while developing analytical skills and gaining experience in handling complex information. (le.ac.uk)
  • Improved knowledge of the genetics and biological processes that determine amino acid levels will enable researchers to use this information for plant breeding and biological discovery. (g3journal.org)
  • Toward this goal, we used genomic prediction to identify biological processes that are associated with, and therefore potentially influence, free amino acid (FAA) composition in seeds of the model plant Arabidopsis thaliana . (g3journal.org)
  • Taken together, these findings provide evidence that genomic partitioning is a viable strategy to uncover the relative contributions of biological processes to FAA traits in seeds, offering a promising framework to guide hypothesis testing and narrow the search space for candidate genes. (g3journal.org)
  • CD90 regulates key biological processes, such as cell apoptosis, migration, adhesion, cell-cell and cell-matrix interactions and T-cell activation ( 5 - 8 ). (spandidos-publications.com)
  • The technique is based purely on image processing of the input data, rather than numerical reconstruction of scalar fields like vorticity, allowing it to be used as a straightforward 'first pass' characterization technique for biological systems where traditional techniques are either unnecessary to support qualitative observations or prohibitively difficult because of the length and time scales involved. (biologists.org)
  • The risks associated with a soil contaminated by polycyclic aromatic hydrocarbons (PAHs) are generally assessed by measuring individual PAHs in the soil and correlating the obtained amounts to known adverse biological effects of the PAHs. (eugris.info)
  • This publication gives a history of biological warfare (BW) from the prehistoric period through the present, with a section on the future of BW. (gpo.gov)
  • Biological Availability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This is mostly because the natural variability and more complex manufacturing of biological medicines do not allow an exact replication of the molecular micro-heterogeneity. (wikipedia.org)
  • The availability and bioavailability of contaminants in soil also has to be studied further, and such future studies should focus on the molecular interactions between the contaminants and different compartments of the soil. (eugris.info)
  • Such studies would generate the data needed for molecular-based modelling of availability and bioavailability, which would be a big step forward compared to current risk assessment practices. (eugris.info)
  • According to them, analytical studies demonstrate that the biological product is highly similar to the reference product, despite minor differences in clinically inactive components, animal studies (including the assessment of toxicity), and a clinical study or studies (including the assessment of immunogenicity and pharmacokinetics or pharmacodynamics). (wikipedia.org)
  • We contend that a possible hitherto unrecognized mechanism of silicon essentiality in biology is to increase the biological availability of phosphorus in the presence of aluminium. (royalsocietypublishing.org)
  • This module explores a range of advanced topics in biological science from evolution to cell and molecular biology. (open.ac.uk)
  • Biological Science covers major aspects of biology and molecular science across a wide range of organisms from bacteria and fungi to humans and plants. (le.ac.uk)
  • Anthropology 362, on the other hand, addresses itself to two main problem areas where race is concerned: (1) the common concept of race has an inadequate foundation in biology and must be dispensed with before we can make sense out of the very real aspects of human biological variation. (umich.edu)
  • 2) If the common concept of race has an inadequate biological base, how did we get stuck with our generally held assumptions when it would appear that they owe more to folklore than to biology? (umich.edu)
  • Brain‑Muscle Arnt‑Like protein 1 (BMAL1) and Circadian Locomotor Output Cycles Kaput (CLOCK) are the main biological rhythm genes. (spandidos-publications.com)
  • The Cancer Genome Atlas (TCGA) database was used to detect the expression levels of the biological rhythm genes BMAL1 and CLOCK in various types of tumor. (spandidos-publications.com)
  • Colony formation experiments were used to detect cell proliferation in each group, cell cycle distribution was detected by flow cytometry and western blotting was used to detect the expression levels of wild‑type and mutant IDH1, cyclins, biological rhythm genes and Smad signaling pathway‑associated genes in U87‑MG cells. (spandidos-publications.com)
  • Therefore, the present results suggested that the IDH1 R132H mutation may alter the cell cycle and biological rhythm genes in U87‑MG cells through the TGF‑β/Smad signaling pathway. (spandidos-publications.com)
  • The enormous increase in scalability it provides empowers users to study complex and previously unassailable gene-set associations between genes and their biological functions in a hierarchical fashion and on a genome-wide scale. (biomedcentral.com)
  • This unit applies the core principles of chemistry, molecular structure and chemical reactivity to biological molecules. (edu.au)
  • Key chemical concepts such as bonding and structure (e.g. chirality) will be used to highlight the function of biological building blocks (lipids, carbohydrates, amino acids and the nitrogen bases) of large cellular molecules like proteins, DNA and RNA. (edu.au)
  • they develop rigorous expertise in everything from foundational theory and the study of evolution to cutting-edge research methodologies as they investigate a broad range of biological problems ranging from the molecular level to the biosphere. (ucalgary.ca)
  • MRPC learns a causal biological network efficiently and robustly from integrating individual-level genotype and molecular phenotype data, in which directed edges indicate causal directions. (frontiersin.org)
  • Here, all-atom molecular dynamics simulations are leveraged to investigate the capsid without symmetry bias, enabling study of capsid flexibility and its implications for biological function and cryo-EM resolution limits. (elifesciences.org)
  • In order to identify the molecular mechanism by which CD90 affects the biological behavior and energy metabolism of gastric cancer cells, the present study used Cell Counting Kit‑8 assays, lactate concentration determination and ATP content determination. (spandidos-publications.com)
  • investigation of the influence of tensides and other dissolved organic compounds on the biological availability and degradation of PAHs. (osti.gov)
  • However, the link between the chemical analyses and the biological tests could be improved as as an organic solvent that solubilised virtually all of the contaminants was used during the chemical analysis while the biological tests were performed in an aqueous solution with limited solubility for a number of compounds. (eugris.info)
  • Winter Academic Term '02 Time Schedule for Biological Anthropology. (umich.edu)
  • Introduction to Biological Anthropology. (umich.edu)
  • Understanding the dynamical behaviour of biological systems is challenged by their large number of components and interactions. (springer.com)
  • In conclusion, Principal Process Analysis is a simple-to-use method, which constitutes an additional and useful tool for analysing the complex dynamical behaviour of biological systems. (springer.com)
  • Before booking, please check the calendars for embryo booking , behaviour room and microscope room availability . (qmul.ac.uk)
  • Coastal marine ecosystems harbor high biological diversity and are among the most productive systems in the world [1] , [2] . (plos.org)
  • While the likelihood of terrorist attacks involving chemical, radiological, nuclear, and biological weapons is highly uncertain, such attacks can create circumstances in which individuals would need to be concerned with protecting their safety and health and, perhaps, even their lives. (rand.org)
  • Recovering amphibious forces can be complicated if ashore forces are attacked with chemical, biological, or radiological weapons. (rand.org)
  • abstract = "The effect of glucose and other monosaccharide availability in culture medium on production of antibody by human hybridomas has been studied. (elsevier.com)
  • Abstract This study seeks to understand biological cancer drug availability through registration and prices of the biological agents used for cancer therapy and authorized for sale in the last 5 years in Brazil , Colombia , and Mexico , comparing the data to those for the United States of America (USA) and Spain . (bvsalud.org)
  • That research created mutant viruses that could be dangerous to humans and, critics say, potentially be used as biological weapons. (npr.org)
  • In two metabolism trials with 18 wether lambs, the biological availability of magnesium was determined for the two forages cut at three stages of maturity. (vt.edu)
  • The validity of such a risk estimation is dependent on the presence of additional compounds, the availability of the compounds (including the PAHs), and the methods used to correlate the measured chemical data and biological effects. (eugris.info)
  • In the work underlying this thesis the availability, chemical composition and biological effects of PAHs in samples of soils from PAH-contaminated environments were examined. (eugris.info)
  • Consequently the compounds probably have a different impact in the biological tests than their relative abundance in profiles obtained by standard chemical analyses suggests. (eugris.info)
  • The U.S. national civilian vulnerability to the deliberate use of biological and chemical agents has been highlighted by recognition of substantial biological weapons development programs and arsenals in foreign countries, attempts to acquire or possess biological agents by militants, and high-profile terrorist attacks. (cdc.gov)
  • In partnership with representatives for local and state health departments, other federal agencies, and medical and public health professional associations, CDC has developed a strategic plan to address the deliberate dissemination of biological or chemical agents. (cdc.gov)
  • The plan contains recommendations to reduce U.S. vulnerability to biological and chemical terrorism --- preparedness planning, detection and surveillance, laboratory analysis, emergency response, and communication systems. (cdc.gov)
  • An act of biological or chemical terrorism might range from dissemination of aerosolized anthrax spores to food product contamination, and predicting when and how such an attack might occur is not possible. (cdc.gov)
  • The public health infrastructure must be prepared to prevent illness and injury that would result from biological and chemical terrorism, especially a covert terrorist attack. (cdc.gov)
  • As with emerging infectious diseases, early detection and control of biological or chemical attacks depends on a strong and flexible public health system at the local, state, and federal levels. (cdc.gov)
  • This report is a summary of the recommendations made by CDC's Strategic Planning Workgroup in Preparedness and Response to Biological and Chemical Terrorism: A Strategic Plan ( CDC, unpublished report, 2000 ), which outlines steps for strengthening public health and health-care capacity to protect the United States against these dangers. (cdc.gov)
  • They are used to create fast-responding sensors with good sensitivity and selectivity for the detection of chemical species and biological agents. (dymocks.com.au)
  • provides an overview of developments brought about by the application of nanotechnology for both chemical and biological sensor development. (dymocks.com.au)
  • With massive increases in the availability of ecological and other kinds of biological data, skill in developing models to describe and understand relationships in data and extrapolate beyond existing data, and an understanding of the nuances of particular kinds of data, is fundamental in modern biological research. (edu.au)
  • The biological and ecological factors liable to induce a change in the radio-sensitivity of a species are undoubtedly responsible for the large fluctuations observed during radio-biological experiments. (osti.gov)
  • Influence des facteurs biologiques et ecologiques sur la radiosensibilite des animaux de laboratoire} author = {Guenet, J L, and Legeay, G} abstractNote = {The biological and ecological factors liable to induce a change in the radio-sensitivity of a species are undoubtedly responsible for the large fluctuations observed during radio-biological experiments. (osti.gov)
  • Evaluation of this vulnerability has focused on the role public health will have detecting and managing the probable covert biological terrorist incident with the realization that the U.S. local, state, and federal infrastructure is already strained as a result of other important public health problems. (cdc.gov)
  • PALM SPRINGS, CA, March 14, 2019 -During the Spring CUE conference, Carolina Biological Supply Company, the leading school science supplier, launched new Spanish language instructional materials for schools using Building Blocks of Science ™ 3D . (carolina.com)
  • NICHD is issuing this Notice to alert interested investigators to the availability of biospecimens and environmental sample materials from the National Children's Study (NCS) Vanguard. (nih.gov)
  • 5) The term 'biosimilar biological product development meeting' means any meeting, other than a biosimilar initial advisory meeting, regarding the content of a development program, including a proposed design for, or data from, a study intended to support a biosimilar biological product application. (house.gov)
  • Australian citizens, permanent residents and international students studying outside Australia may have the choice of full-time, part-time and external study, depending on course availability and in-country requirements. (edu.au)
  • The present study investigates in-depth the availability of MudPIT data for the classification of biological samples. (biomedcentral.com)
  • The present study aimed to further study whether there is an association between IDH1 R132H mutation and biological rhythm in glioma, and whether this affects the occurrence of glioma. (spandidos-publications.com)
  • The new method is streamlined, efficient, and particularly well-suited to the study of huge and diverse biological data. (biomedcentral.com)
  • In this study, we performed an analysis of inter-regional and inter-annual differences in temperature (T) conditions associated with MMEs of the red gorgonian Paramuricea clavata by analyzing high resolution T time series (hourly records for 3 to 8 years) from four regions of the NW Mediterranean with differing hydrological conditions and biological impacts. (plos.org)
  • Because her topic is a mixture of civil and biological engineering she's able to make practical use of her study and classes such as hydrology, fluid mechanics and hydraulics, statics and geographic information systems. (ncat.edu)
  • Each biological problem is accompanied by precise formulations, providing graduate students and researchers in bioinformatics and computer science with a powerful toolkit for the emerging applications of high-throughput sequencing. (cambridge.org)
  • This research was supported in part by the 2004 Pfizer Fellowship in Biological Psychiatry, funded by Pfizer U.S. Pharmaceuticals, awarded to Amelia Gallitano. (plos.org)
  • 4)(A) Subject to subparagraph (B), the term 'biosimilar biological product application' means an application for licensure of a biological product under section 262(k) of title 42 . (house.gov)
  • They are sufficient to demonstrate safety, purity, and potency in one or more appropriate conditions of use for which the reference product is licensed and is intended to be used and for which licensure is sought for the biological product. (wikipedia.org)
  • The availability of resources strongly influences an individual's ability to modulate investment in sexually selected traits. (royalsocietypublishing.org)
  • As the production and maintenance of traits mediated by pre- and postcopulatory sexual selection is energetically demanding [ 12 , 13 ], an increased investment in traits subject to both episodes of sexual selection can be expected under conditions of high resource availability. (royalsocietypublishing.org)
  • By contrast, under limitation an increased allocation in one function often results in a decreased resource availability for alternative functions [ 14 ], leading to one of the major predictions of sperm competition theory that a male's investment should be traded-off between pre- and postcopulatory traits [ 15 ]. (royalsocietypublishing.org)
  • Experimental manipulation of diet is a suitable approach to explore the impact of variation in resource availability on the expression of pre- and postcopulatory traits and their interrelationship. (royalsocietypublishing.org)
  • These will be contrasted with the biological traits that show regional clustering but which have no adaptive value and cannot therefore be hierarchically arranged. (umich.edu)
  • 3) The term 'biosimilar biological product' means a specific strength of a biological product in final dosage form for which a biosimilar biological product application has been approved. (house.gov)
  • 6) The term 'biosimilar biological product development program' means the program under this subpart for expediting the process for the review of submissions in connection with biosimilar biological product development. (house.gov)
  • ii) at which one or more biosimilar biological products are manufactured in final dosage form. (house.gov)
  • D) collecting fees under section 379j-52 of this title and accounting for resources allocated for the review of submissions in connection with biosimilar biological product development, biosimilar biological product applications, and supplements. (house.gov)
  • 10) The term 'final dosage form' means, with respect to a biosimilar biological product, a finished dosage form which is approved for administration to a patient without substantial further manufacturing (such as lyophilized products before reconstitution). (house.gov)
  • A biosimilar is not regarded as a generic of a biological medicine. (wikipedia.org)
  • When a company applies for marketing authorization at EMA, data are evaluated by EMA's scientific committees on human medicines and on safety (the CHMP and PRAC), as well as by EU experts on biological medicines (Biologics Working Party) and specialists in biosimilars (Biosimilar Working Party). (wikipedia.org)
  • We apply this technique to a variety of biological systems, including the swimming currents of invertebrates and the collective motion of swarms of insects. (biologists.org)
  • A variety of biological challenges can be addressed by finding maximal bicliques in bipartite graphs. (biomedcentral.com)
  • We consider for this approach fuzzy set as a formalism of analysis of biological signals processing and we propose to be accomplished this goal by developing fuzzy operators for filtering the noise of biological signals measurement. (igi-global.com)
  • DA 1.0: parameter estimation of biological pathways using data assimilation approach. (nih.gov)
  • The integrated data from various online databases makes it easy to identify the biological relevance of nodes in the network. (springer.com)
  • However, the regulatory ERA framework could be improved by (i) inclusion of the environment in the risk-benefit analysis for human pharmaceuticals, (ii) improvement of risk management options, (iii) generation of data on existing pharmaceuticals, and (iv) improving the availability of ERA data. (royalsocietypublishing.org)
  • In order to minimize the quantity of pharmaceuticals in the environment these should aim to (i) improve the existing legislation for pharmaceuticals, (ii) prioritize pharmaceuticals in the environment and (iii) improve the availability and collection of pharmaceutical data. (royalsocietypublishing.org)
  • Innovative Formalism for Biological Data Analysis. (igi-global.com)
  • This book constitutes the refereed proceedings of the 5th International Symposium on Biological and Medical Data Analysis, ISBMDA 2004, held in Barcelona, Spain in November 2004. (barnesandnoble.com)
  • Statistical Methods and Tools for Biological and Medical Data Analysis. (barnesandnoble.com)
  • However, the formal detection and attribution of biological responses to climate change is associated with many challenges. (nature.com)
  • We discuss whether formal detection and/or attribution is necessary and suggest ways in which understanding of biological responses to extreme events could progress. (nature.com)
  • A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples. (thefreelibrary.com)
  • It can be concluded from the results presented in the included papers that the PAHs in the studied soils from industrial sites were not generally physically trapped in soil material, indicating that the availability of the PAHs was not restricted in this sense. (eugris.info)
  • It collected more than 14 million records and nearly 19,000 biological and 5,500 environmental primary samples from which a sample repository of over 250,000 items was created. (nih.gov)
  • Primarily employed for biomarker discovery, it is increasingly used for developing methods which may help to provide unambiguous diagnosis of biological samples. (biomedcentral.com)
  • The identification of proteins changing their quantitative level is a key aspect to investigate biological systems as well as to develop strategies for classifying samples into pre-specified categories, such as healthy and diseased. (biomedcentral.com)
  • We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples. (biomedcentral.com)
  • Sequencing viral genomes directly from clinical and biological samples, however, holds special challenges. (biomedcentral.com)
  • Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. (semanticscholar.org)
  • Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. (clinicaltrials.gov)
  • The University reserves the right to amend or remove courses and unit availabilities, as appropriate. (edu.au)
  • The item Biological availability of pollutants to marine organisms, by John R. Montgomery [and others], Center for Energy and Environment Research represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries . (missouri.edu)
  • At the University of Leicester, we offer seven Biological Science subjects and four Medical Bioscience subjects, all as both BSc (three years) and MBiolSci (four years), plus a Foundation Year option, giving you an impressive range of 23 different courses to choose from. (le.ac.uk)
  • He's a professor of chemistry at Rutgers University who has long called for better control of biological research that could be misused. (npr.org)
  • Dr. Godfrey Gayle, a professor of biological engineering, has secured a $400,000 contract with the U.S. Department of Agriculture's Natural Resources Conservation Service to provide scholarships and other support to students studying biological engineering at North Carolina Agricultural and Technical State University. (ncat.edu)
  • North Carolina A&T State University senior, biological engineering student Madeline Keefer will spend nine months studying flood management in the Netherlands thanks to a Fulbright U.S. Student Programs Grant jointly sponsored by the Netherland-America Foundation. (ncat.edu)
  • Are there important biological interactions that are important in this environment? (kenyon.edu)
  • Its application has enabled researchers to address important biological questions, often for the first time. (cambridge.org)
  • To test how dietary resource availability affects sexual ornamentation, sperm quality and their interrelationship in three-spined sticklebacks ( Gasterosteus aculeatus ), full-sibling groups were raised under three conditions differing in food quantity and/or quality (i.e. carotenoid content): (i) high-quantity/high-quality, (ii) high-quantity/low-quality or (iii) low-quantity/low-quality. (royalsocietypublishing.org)
  • These results suggest that change of glucose availability affects the antigen-binding activity of the antibody via the alteration of the glycosylation. (elsevier.com)
  • It can visualize the dynamic perturbations in biological networks and allows the user to investigate the changes over time. (springer.com)
  • Nevertheless, because of certain biological properties of UCB compared with bone marrow, UCB cells will grow or "engraft" in most patients and result in reconstitution of the haematopoietic and immune cells. (mja.com.au)
  • Here we present DynOVis, a network visualization tool that can capture dynamic dose-over-time effects in biological networks. (springer.com)
  • Currently there are a number of different tools available that focus on visualizing dynamic networks [ 9 , 10 , 11 ], but these do not focus on the integration of dynamic visualization with biological knowledge. (springer.com)
  • To improve upon this, we developed a tool that integrates dynamic network visualization with functional biological information. (springer.com)
  • Medical professionals learn about effective available medical countermeasures against many of the bacteria, viruses, and toxins that might be used as biological weapons against military forces or civilian communities. (gpo.gov)
  • Since the first edition in 1993, the awareness of biological weapons in the U.S. has increased dramatically. (gpo.gov)
  • In-depth definitions of biological agents, biological weapons, and biological warfare (BW) are included, as well as an appendix of further reading on the subject. (gpo.gov)
  • Describe biological interactions that might take place in this environment, using as many sections/subsections as you require. (kenyon.edu)
  • Save 12% on the Handbook of Biological Confocal Microscopy (The Language of Science) by Springer at Translate This Blog. (translateth.is)
  • Known as the USAMRIID Blue Book, this invaluable handbook supplies basic summary and treatment information quickly for the healthcare provider on the front lines of a biological incident. (gpo.gov)
  • The purpose of this handbook is to serve as a concise, pocket-sized manual that can be pulled off the shelf (or from a pocket) in a crisis to guide medical personnel in the prophylaxis and management of biological casualties. (gpo.gov)
  • The Medical Management of Biological Casualties Handbook, which has been known as the "Blue Book" has been enormously successful. (gpo.gov)
  • The EPNs have been used as biological control agents to effectively impress a large number of economically important insect pests (Grewal et al. (springer.com)
  • and biological agents. (hse.gov.uk)
  • A greater in-depth discussion of the agents covered here may be found in the Army Surgeon General's Borden Institute Textbook of Military Medicine, "Medical Aspects of Biological Warfare" (2007) and in relevant infectious disease, tropical medicine, and disaster management textbooks. (gpo.gov)
  • Target audience are military and civilian healthcare providers treating biological warfare injuries, and members of the military, defense agencies and relevant contractors that need to know the different bacterial and viral agents and biological toxins being used in warfare (and need to stay current on bioterrorist threats). (gpo.gov)
  • Wheat, a tetany prone forage, and orchardgrass, a non-tetany prone forage, were cut at three stages of maturity to determine the magnesium availability in these forages for lambs. (vt.edu)
  • The biological availability of magnesium for lambs fed wheat was slightly lower than for those fed orchardgrass. (vt.edu)
  • Examine theories of biological aging, normal physiological and anatomical changes, changing requirements for nutrition and physical activity, including health promotion. (centennialcollege.ca)
  • Description: Molybdenum, Phosphorous, and Nitrogen Availability Control Rates of Biological N2-fixation in Boreal Peatlands / Katherine Dynarski. (villanova.edu)
  • The environmental assessment considers the effects of, and alternatives to, the release of a nonindigenous gall mite, Floracarus perrepae, for the biological control of Old World climbing fern in Florida. (federalregister.gov)
  • SMMC7721, Bel-7402, and MHCC97 human liver cancer cells used in this work were commercially available from the Beijing National Institute for the Control of Biological and Pharmaceutical Products (China). (hindawi.com)
  • Biological control by entomopathogenic nematodes (EPNs) is one of the alternatives to manage the turnip moth, Agrotis segetum (Denis & Schiffermuller) (Lepidoptera: Noctuidae). (springer.com)
  • This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations for the production and control of vaccines and other biological substances, and the establishment of international biological reference materials. (tsoshop.co.uk)
  • Students will also learn to contextualize the neurobiological aspects of addictions within a multidimensional framework that includes biological, psychological and social/structural factors. (centennialcollege.ca)
  • This graph shows the total number of publications written about "Biological Availability" by people in this website by year, and whether "Biological Availability" was a major or minor topic of these publications. (umassmed.edu)
  • It is possible to switch between a Biological Science course and a Medical Bioscience course during the first half of your first year, but after that the two fields diverge. (le.ac.uk)
  • The two-year contract seeks to increase enrollment and improve retention of undergraduate and graduate students studying biological engineering, especially natural resources and agricultural engineering programs in the CAES. (ncat.edu)
  • 200 each year pending availability of funds. (nsf.gov)
  • 72,000,000 for new awards each year pending availability of funds. (nsf.gov)
  • 2. What are Biological Soil Crusts? (slideshare.net)
  • Cyanobacteria and Moss Lichen Lycopod This biological soil crust is found in the Central Range of the Dominican Republic. (slideshare.net)
  • To identify the macroscopic species that make up the biological soil crust at the Rome Sand Plains. (slideshare.net)
  • To determine the water absorption capacity of the biological soil crust under different environmental conditions. (slideshare.net)
  • To measure soil stability due to biological soil crust cover. (slideshare.net)
  • To estimate the total surface area covered with biological soil crust in the Rome Sand Plains and map the area. (slideshare.net)