Biochemical processes. Medical search

Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things.

The study of the composition, chemical structures, and chemical reactions of living things.

The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.

Computer-based representation of physical systems and phenomena such as chemical processes.

The rate dynamics in chemical or physical systems.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.

The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.

Elements of limited time intervals, contributing to particular results or situations.

Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).

Established cell cultures that have the potential to propagate indefinitely.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.

The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.

A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.

Proteins prepared by recombinant DNA technology.

The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.

The relationships of groups of organisms as reflected by their genetic makeup.

The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.

Proteins found in any species of bacterium.

Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.

The parts of a macromolecule that directly participate in its specific combination with another molecule.

The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.

The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.

The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).

Deoxyribonucleic acid that makes up the genetic material of bacteria.

An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.

The sum of the weight of all the atoms in a molecule.

A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.

Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.

DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.

A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.

The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.

A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.

Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.

Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.

The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.

Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.

Transport proteins that carry specific substances in the blood or across cell membranes.

Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).

An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.

Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.

The process by which two molecules of the same chemical composition form a condensation product or polymer.

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.

Tumors or cancer of the PROSTATE.

The process of cleaving a chemical compound by the addition of a molecule of water.

The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.

The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.

A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.

Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.

Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.

An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

The relationship between the dose of an administered drug and the response of the organism to the drug.

The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.

Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.

The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.

Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.

Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.

The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.

Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.

Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.

An examination of chemicals in the blood.

Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

The characteristic 3-dimensional shape and arrangement of multimeric proteins (aggregates of more than one polypeptide chain).

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.

The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.

An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.

A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell.

Commonly observed structural components of proteins formed by simple combinations of adjacent secondary structures. A commonly observed structure may be composed of a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.

Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.

Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.

The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

Proteins found in any species of fungus.

The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.

The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)

A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.

Genes, found in both prokaryotes and eukaryotes, which are transcribed to produce the RNA which is incorporated into RIBOSOMES. Prokaryotic rRNA genes are usually found in OPERONS dispersed throughout the GENOME, whereas eukaryotic rRNA genes are clustered, multicistronic transcriptional units.

The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

Proteins obtained from ESCHERICHIA COLI.

Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.

Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.

A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.

Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.

Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)

The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.

Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.

The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

The facilitation of biochemical reactions with the aid of naturally occurring catalysts such as ENZYMES.

The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.

Techniques to partition various components of the cell into SUBCELLULAR FRACTIONS.

The functional hereditary units of BACTERIA.

Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.

Components of a cell produced by various separation techniques which, though they disrupt the delicate anatomy of a cell, preserve the structure and physiology of its functioning constituents for biochemical and ultrastructural analysis. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p163)

The co-occurrence of pregnancy and NEOPLASMS. The neoplastic disease may precede or follow FERTILIZATION.

Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).

A mutation in which a codon is mutated to one directing the incorporation of a different amino acid. This substitution may result in an inactive or unstable product. (From A Dictionary of Genetics, King & Stansfield, 5th ed)

A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.

The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)

One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.

The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.

Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)

Stable phosphorus atoms that have the same atomic number as the element phosphorus, but differ in atomic weight. P-31 is a stable phosphorus isotope.

A mutation caused by the substitution of one nucleotide for another. This results in the DNA molecule having a change in a single base pair.

Gases or volatile liquids that vary in the rate at which they induce anesthesia; potency; the degree of circulation, respiratory, or neuromuscular depression they produce; and analgesic effects. Inhalation anesthetics have advantages over intravenous agents in that the depth of anesthesia can be changed rapidly by altering the inhaled concentration. Because of their rapid elimination, any postoperative respiratory depression is of relatively short duration. (From AMA Drug Evaluations Annual, 1994, p173)

Cellular processes, properties, and characteristics.

Single chains of amino acids that are the units of multimeric PROTEINS. Multimeric proteins can be composed of identical or non-identical subunits. One or more monomeric subunits may compose a protomer which itself is a subunit structure of a larger assembly.

Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)

The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.

A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.

Inorganic salts of phosphoric acid.

An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins.

A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Macromolecular complexes formed from the association of defined protein subunits.

A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.

Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Proteins that originate from plants species belonging to the genus ARABIDOPSIS. The most intensely studied species of Arabidopsis, Arabidopsis thaliana, is commonly used in laboratory experiments.

Techniques used in studying bacteria.

A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.

Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)

The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.

The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.

Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.

One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.

A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.

An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.

Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.

Serologic tests in which a positive reaction manifested by visible CHEMICAL PRECIPITATION occurs when a soluble ANTIGEN reacts with its precipitins, i.e., ANTIBODIES that can form a precipitate.

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.

CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CERCOPITHECUS AETHIOPS).)

Proteins found in any species of virus.

Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.

An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA.

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.

Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.

Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.

Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.

Antibodies produced by a single clone of cells.

An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.

Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.

Presence of warmth or heat or a temperature notably higher than an accustomed norm.

A family of enzymes that catalyze the conversion of ATP and a protein to ADP and a phosphoprotein.

The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.

Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.

A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.

The fractal geometry of nutrient exchange surfaces does not provide an explanation for 3/4-power metabolic scaling. (1/86)

BACKGROUND: A prominent theoretical explanation for 3/4-power allometric scaling of metabolism proposes that the nutrient exchange surface of capillaries has properties of a space-filling fractal. The theory assumes that nutrient exchange surface area has a fractal dimension equal to or greater than 2 and less than or equal to 3 and that the volume filled by the exchange surface area has a fractal dimension equal to or greater than 3 and less than or equal to 4. RESULTS: It is shown that contradicting predictions can be derived from the assumptions of the model. When errors in the model are corrected, it is shown to predict that metabolic rate is proportional to body mass (proportional scaling). CONCLUSION: The presence of space-filling fractal nutrient exchange surfaces does not provide a satisfactory explanation for 3/4-power metabolic rate scaling. (+info)

Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model. (2/86)

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Different types of cell-to-cell connections mediated by nanotubular structures. (3/86)

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Solution NMR structure determination of proteins revisited. (4/86)

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Astrocytes as the glucose shunt for glutamatergic neurons at high activity: an in silico study. (5/86)

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Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. (6/86)

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Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism. (7/86)

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Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites. (8/86)

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Biochemical engineers use their knowledge of chemical processes in biological systems in order to create tangible products that ... A common job for biochemical engineers working in the food industry is to design ways to perform all these processes on a large ... Biochemical engineers primarily focus on designing systems that will improve the production, processing, packaging, storage, ... Some commonly processed foods include wheat, fruits, and milk which undergo processes such as milling, dehydration, and ...

https://en.wikipedia.org/wiki/Biochemical_engineering

Biochemical Pharmacology. 24 (18): 1701-1705. doi:10.1016/0006-2952(75)90009-x. ISSN 0006-2952. PMID 13. Amason, Allen C.; ... Process conflict refers to disagreement over the group's approach to the task, its methods, and its group process. They note ... Conflict is a social process that is exacerbated when individual members of a group take sides in the debate. Among the methods ... Put simply, the mediator can be thought of as a disinterested guide directs the disputants through the process of developing a ...

https://en.wikipedia.org/wiki/Conflict_(process)

and its antifungal, anticancer and antimetastatic activities". Sustainable Chemical Processes. 2 (1): 8. doi:10.1186/2043-7129- ... 2-8. Freeman, G.G.; Morrison, R.I. (1949). "Metabolic products of Trichothecium roseum Link". Biochemical Journal. 45 (2): 191- ...

https://en.wikipedia.org/wiki/Trichothecium_roseum

Kuhnle, G.G.C.; Bingham, S.A. (1 November 2007). "Dietary meat, endogenous nitrosation and colorectal cancer". Biochemical ... Meat processing includes all the processes that change fresh meat with the exception of simple mechanical processes such as ... Processed meat is considered to be any meat which has been modified in order to either improve its taste or to extend its shelf ... Processed meat is usually composed of pork or beef, but also poultry, while it can also contain offal or meat by-products such ...

https://en.wikipedia.org/wiki/Processed_meat

Foundations of a query and simulation system for the modeling of biochemical and biological processes. In Pacific Symposium on ... Most biochemical cascades are series of events, in which one event triggers the next, in a linear fashion. Biochemical cascades ... genetic information processing, environmental information processing such as signal transduction, ligand-receptor interaction ... Biological processes, Chemical kinetics, Enzyme kinetics, Chemical processes, Complement system, Signal transduction). ...

https://en.wikipedia.org/wiki/Biochemical_cascade

Biochemical Evolution. Biothermodynamics: The Study of Biochemical Processes at Equilibrium. with John Edsall Kinetics for the ... Edsall, John; Gutfreund, Herbert (1983). Biothermodynamics: The Study of Biochemical Processes at Equilibrium. Wiley-Blackwell ... "Biochemical Society - Honorary Members". Biochemistry.org. Retrieved 1 November 2018. (Use dmy dates from February 2022, ... Gutfreund H (1999). "Rapid-flow techniques and their contributions to enzymology". Trends in Biochemical Sciences. 24: 458-460 ...

https://en.wikipedia.org/wiki/Herbert_Gutfreund

Process Biochemistry. 40: 3383-3388. doi:10.1016/j.procbio.2005.03.017. Adams, J. (2014). "Electro‐Biochemical Reactor (EBR) ... Electro-biochemical reactor (EBR) is a type of a bioreactor used in water treatment. EBR is a high-efficiency denitrification, ... The Electro-Biochemical Reactor directly supplies needed electrons to the reactor and microbes[unreliable source?], using a low ... Opara, A.; Adams, D.J.; Martin, A.J (2014). "Electro-biochemical reactor (EBR) technology for selenium removal from British ...

https://en.wikipedia.org/wiki/Electro-biochemical_reactor

Molecular and Biochemical Parasitology. 134 (1): 53-64. doi:10.1016/j.molbiopara.2003.11.001. ISSN 0166-6851. PMID 14747143. ... The process resulting in a variation of somatic genome that differs from germline genome is called somatic genome processing. ... The result of this process is the removal of a whole genome from a cell. The most known example is the enucleation process of ... A processed stem cell goes through changes causing it to lose a nucleus. In the beginning phase, pro-erythroblast goes through ...

https://en.wikipedia.org/wiki/Somatic_genome_processing

Scientists do know that during this process, the level of cytoplasmic vesicles is significantly reduced, which is thought to be ... Wang, Z. (2003). "Gene discovery in the Entamoeba invadens genome". Molecular and Biochemical Parasitology. 129 (1): 23-31. doi ... Welter, Brenda (2017). "Flow cytometric characterization of encystation in Entamoeba invadens". Molecular and Biochemical ... Segovia-Gamboa, Norma Cristina (2010). "Entabmoeba Invadens, encystation process and enolase". Experimental Parasitology. 125 ( ...

https://en.wikipedia.org/wiki/Entamoeba_invadens

Hochachka, P.W.; Somero, G. N (2002). "Biochemical Adaptation. Mechanism and Process in Physiological Evolution". Oxford: ...

https://en.wikipedia.org/wiki/Osmolyte

Process Biochemistry. 45 (6): 874-98. doi:10.1016/j.procbio.2010.02.007. Wang H, Ng TB (2003). "A ribonuclease with distinctive ... features from the wild green-headed mushroom Russulus virescens". Biochemical and Biophysical Research Communications. 312 (4 ... and collectively they play a critical role in many biological processes. A RNase from R. virescens was shown to be ...

https://en.wikipedia.org/wiki/Russula_virescens

... processing of enzyme activators and inhibitors, brain antigen processing and regulation of programmed cell death. Cathepsin D ... Knight CG, Barrett AJ (April 1976). "Interaction of human cathepsin D with the inhibitor pepstatin". The Biochemical Journal. ... Devosse T, Dutoit R, Migeotte I, De Nadai P, Imbault V, Communi D, Salmon I, Parmentier M (August 2011). "Processing of HEBP1 ... March 2006). "Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial ...

https://en.wikipedia.org/wiki/Cathepsin_D

is a convenient, readily applicable technique which is used extensively ... study of biochemical radical processes. The ...

https://en.wikipedia.org/wiki/Spin_trapping

Ikeda M (2002). "Amino acid production processes". Microbial Production of l-Amino Acids. Advances in Biochemical Engineering/ ... 1969). Data for Biochemical Research. Oxford: Clarendon Press. ISBN 0-19-855338-2. "Nomenclature and Symbolism for Amino Acids ... Radwanski ER, Last RL (1995). "Tryptophan biosynthesis and metabolism: biochemical and molecular genetics". The Plant Cell. 7 ( ... In addition, tryptophan functions as a biochemical precursor for the following compounds: Serotonin (a neurotransmitter), ...

https://en.wikipedia.org/wiki/Tryptophan

"Cell Factories for Industrial Production Processes: Current Issues and Emerging Solutions". Processes. 8 (7): 768. doi:10.3390/ ... Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer. 30: 147-194. doi:10.1007/BFb0006382. ISBN 978- ... Fed-batch culture is, in the broadest sense, defined as an operational technique in biotechnological processes where one or ... By having multiple approaches for MCF, companies may customize each process to their specific product(s). The commercialization ...

https://en.wikipedia.org/wiki/Microbial_cell_factory

Diagnosis is made on the basis of the clinical picture in association with biochemical studies revealing erythrocyte GPI ... Baker S (1976). "Pure fructose syrups". Process Biochemistry. 11: 20-25. Antrim RL, Colilla W, Schnyder BJ (1979). "Glucose ... Wang PY, Shopsis C, Schneider H (May 1980). "Fermentation of a pentose by yeasts". Biochemical and Biophysical Research ... Isomerases catalyze reactions across many biological processes, such as in glycolysis and carbohydrate metabolism. Examples of ...

https://en.wikipedia.org/wiki/Isomerase

The process was termed "counter-current liquid-liquid extraction." Martin and Synge described the theory of this technique in ... 2. Application to the micro-determination of the higher monoamino-acids in proteins". Biochemical Journal. 35 (12): 1358-1368. ... They would later receive the 1952 Nobel Prize in Chemistry "for their invention of partition chromatography". The process of ... Chromatographic separation was considered to occur by an adsorption process whereby compounds adhered to a solid media and were ...

https://en.wikipedia.org/wiki/Partition_chromatography

Involve a complexity of biochemical processes. Decrease entropy of an organism (lowering oxygen consumption, body temperature, ...

https://en.wikipedia.org/wiki/Actoprotector

Integrated Biochemical Processes for Liquid Biofuels. Elsevier. p. 59. ISBN 9780444594983. Cherubini, Francesco; Jungmeier, ... This operation includes pressing, milling, separation, distillation, among others Biochemical: Processes under low temperature ... Processes: Conversion process to transform biomass into a final product: Mechanical/physical: The chemical structure of the ... Chemical processes: The substrate suffer change by the action of an external chemical (e.g., hydrolysis, transesterification, ...

https://en.wikipedia.org/wiki/Biorefinery

Biochemical and Processing Aspects. CRC Press. pp. 241-. ISBN 978-1-4200-1287-3. Bauer R, Khan IA, Wagner H. Echinacea-Drogen, ...

https://en.wikipedia.org/wiki/Chicoric_acid

In this process antibodies to Aβ are used to decrease cerebral plaque levels. This is accomplished by promoting microglial ... A number of genetic, cell biology, biochemical and animal studies using experimental models support the concept that Aβ plays a ... These aggregate processes can also be studied on lipid bilayer constructs. TPM21 Sylvain Lesné - Aβ*56 Vivekanandan S, Brender ... Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L (January 2010). "Signaling effect of amyloid-beta(42) on the processing of A ...

https://en.wikipedia.org/wiki/Amyloid_beta

Calder, Philip C. (2017-10-15). "Omega-3 fatty acids and inflammatory processes: from molecules to man". Biochemical Society ... Angiogenesis is a process where tumors have their own blood supply in order to feed growing cancer cells. The alliinase ... The "Western pattern diet" consists of high-fat, high-sugar, low-fiber meals with surfeit of salt and highly processed food, ... The role of proteins as enzymes and/or hormones is imperative for cell function and physiological processes as simple as growth ...

https://en.wikipedia.org/wiki/Nutritional_immunology

Lutwak-Mann C (December 1942). "The effect of salicylate and cinchophen on enzymes and metabolic processes". The Biochemical ...

https://en.wikipedia.org/wiki/Cinchophen

PDMPs have been shown useful in ruin theory, queueing theory, for modelling biochemical processes such as DNA replication in ... Cassandras, Christos G.; Lygeros, John (2007). "Chapter 9. Stochastic Hybrid Modeling of Biochemical Processes" (PDF). ... In probability theory, a piecewise-deterministic Markov process (PDMP) is a process whose behaviour is governed by random jumps ... and hence all piecewise-deterministic Markov processes) Davis, M. H. A. (1984). "Piecewise-Deterministic Markov Processes: A ...

https://en.wikipedia.org/wiki/Piecewise-deterministic_Markov_process

CS1: long volume value, Biochemical separation processes). ... leading to an increase in entropy and making this process ...

https://en.wikipedia.org/wiki/Ammonium_sulfate_precipitation

... in which biochemical processes are represented using power-law expansions in the variables of the system. This framework, which ... Biochemical systems theory is a mathematical modelling framework for biochemical systems, based on ordinary differential ... j represents the nf biochemical processes affecting the dynamics of the species. On the other hand, μ {\displaystyle \mu } ij ( ... Eberhard Voit and others for the systems analysis of biochemical processes. According to Cornish-Bowden (2007) they "regarded ...

https://en.wikipedia.org/wiki/Biochemical_systems_theory

"Controlling EDTA treatment to produce permeable escherichia coli with normal metabolic processes". Biochemical and Biophysical ...

https://en.wikipedia.org/wiki/Phloxine

Jukes, T. H.; Holmquist, R. (1972). "Evolution of transfer RNA molecules as a repetitive process". Biochemical and Biophysical ... Crick's suggestion that there might someday be a new science of "biochemical theology" seems to have been realised under an ... Crick and Koch proposed that consciousness seems so mysterious because it involves very short-term memory processes that are as ... In his thinking about the biological processes linking DNA genes to proteins, Crick made explicit the distinction between the ...

https://en.wikipedia.org/wiki/Francis_Crick

Additionally, a processed NAA10 gene duplication NAA11 (ARD2) has been identified that is expressed in several human cell lines ... The Biochemical Journal. 386 (Pt 3): 433-43. doi:10.1042/bj20041071. PMC 1134861. PMID 15496142. Park JH, Seo JH, Wee HJ, Vo TT ... Chang HH, Falick AM, Carlton PM, Sedat JW, DeRisi JL, Marletta MA (August 2008). "N-terminal processing of proteins exported by ... Trends in Biochemical Sciences. 37 (4): 152-61. doi:10.1016/j.tibs.2012.02.003. PMID 22405572. Pruitt KD, Tatusova T, Maglott ...

https://en.wikipedia.org/wiki/N-alpha-acetyltransferase_10

Watson N, Apirion D (November 1981). "Ribonuclease F, a putative processing endoribonuclease from Escherichia coli". ... Biochemical and Biophysical Research Communications. 103 (2): 543-51. doi:10.1016/0006-291X(81)90486-1. PMID 6277308. ... A putative processing endoribonuclease from Escherichia coli". European Journal of Biochemistry. 124 (3): 553-9. doi:10.1111/j. ...

https://en.wikipedia.org/wiki/Ribonuclease_F

... biochemical and metabolic mechanisms that control its copy number and activity in response to changing environmental conditions ... resulted in new understandings of the fundamental metabolic processes by which oncogene amplification drives cancer progression ... and study its biochemical regulation. They demonstrated widespread extrachromosomal oncogene amplification across many cancer ...

https://en.wikipedia.org/wiki/Paul_Mischel

Bencala, Kenneth E. (2000). "Hyporheic zone hydrological processes". Hydrological Processes. 14 (15): 2797-2798. Bibcode: ... between the main stream and the groundwater the hyporheic zone is subjected to physic-chemical gradients generating biochemical ... Often, the hyporheic zone is dominated by heterotrophic microorganisms that process the dissolved nutrients exchanged at this ... Water residence times influence nutrient and carbon processing rates. Longer residence times promote dissolved solute retention ...

https://en.wikipedia.org/wiki/Hyporheic_zone

... (PRA) is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate, and ... PPi The biosynthesis pathway next combines PRA with glycine in a process driven by ATP giving glycineamide ribonucleotide (GAR ...

https://en.wikipedia.org/wiki/Phosphoribosylamine

This does not explain the velocity increase when compared with the uncatalyzed process. A UMP synthase deficiency can result in ... Molecular and Biochemical Parasitology. 134 (2): 245-55. doi:10.1016/j.molbiopara.2003.12.006. PMID 15003844. Breda A, Machado ... Biochemical and Biophysical Research Communications. 390 (2): 337-41. doi:10.1016/j.bbrc.2009.09.128. PMID 19800871. French JB ... Biochemical and Biophysical Research Communications. 363 (1): 216-22. doi:10.1016/j.bbrc.2007.08.164. PMID 17854773. Portal: ...

https://en.wikipedia.org/wiki/Uridine_monophosphate_synthase

He has used biochemical genetics to dissect the main metabolic pathways controlling oil mobilisation in Arabidopsis seed and ... Graham's interests include how plants make and breakdown various metabolites, how these processes are controlled and how they ... Ian Alexander Graham (born 1963) FRS is a professor of Biochemical Genetics in the Centre for Novel Agricultural Products (CNAP ... He has been Chair of Biochemical Genetics at York since 1999. ... Weston Chair of Biochemical Genetics". York: University of York ...

https://en.wikipedia.org/wiki/Ian_A._Graham

An immunohistochemical and biochemical analysis". J. Pathol. 180 (4): 383-8. doi:10.1002/(SICI)1096-9896(199612)180:4. 3.0.CO;2 ... In addition, overexpression of c-Src increases the response of EGFR-mediated processes. So both EGFR and c-Src enhance the ...

https://en.wikipedia.org/wiki/Proto-oncogene_tyrosine-protein_kinase_Src

Lei X, Li YM (December 2009). "The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its ... Biochemical and Biophysical Research Communications. 317 (1): 244-52. doi:10.1016/j.bbrc.2004.03.039. PMID 15047175. Cheng TL, ...

https://en.wikipedia.org/wiki/Rhomboid-related_protein_2

Many experts believe that the processes of daily torpor and hibernation form a continuum and utilise similar mechanisms. The ... Physiological and Biochemical Zoology. 76 (2): 165-179. doi:10.1086/367950. PMID 12794670. S2CID 14675451. Hellgren, Eric C. ( ...

https://en.wikipedia.org/wiki/Hibernation

In the absence of biochemical energy, cells begin to lose the ability to maintain electrochemical gradients. Consequently, ... Raichle, Marcus; Ann Neurol (1983). "The pathophysiology of brain ischemia" (PDF). Neurological Process. Archived from the ...

https://en.wikipedia.org/wiki/Brain_ischemia

The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal ... Biochemical and Biophysical Research Communications. 264 (1): 176-80. doi:10.1006/bbrc.1999.1497. PMID 10527860. Larsen BD, ... This was the key evidence to prove that the CAD form is implicated in this part of the process because without its contribution ... Apoptosis is a cell self-destruct process that removes toxic and/or useless cells during mammalian development and other life ...

https://en.wikipedia.org/wiki/Caspase-activated_DNase

Kozarsky K, Penman M, Basiripour L, Haseltine W, Sodroski J, Krieger M (1989). "Glycosylation and processing of the human ... Biochemical and Biophysical Research Communications. 141 (1): 33-8. doi:10.1016/S0006-291X(86)80330-8. PMID 3099781. Usuki F, ... Pal R, Hoke GM, Sarngadharan MG (May 1989). "Role of oligosaccharides in the processing and maturation of envelope ... Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP (Jun 1989). "Biosynthesis and processing of human immunodeficiency virus ...

https://en.wikipedia.org/wiki/GANC

Wu J, Li L, Wu S, Xu B (August 2020). "CMTM family proteins 1-8: roles in cancer biological processes and potential clinical ... Biochemical and Biophysical Research Communications. 387 (1): 139-42. doi:10.1016/j.bbrc.2009.06.148. PMID 19577543. Wu K, Li X ...

https://en.wikipedia.org/wiki/CKLF-like_MARVEL_transmembrane_domain-containing_5

Regeneration occurs by a process involving DNA single-stranded binding protein and is likely a form of homologous ... Journal of Biochemical Technology. 3 (2): 242-244. ISSN 0974-2328. Reilly, Michael; The Discovery Channel. "World's oldest ...

https://en.wikipedia.org/wiki/Halobacterium_salinarum

Biomedical modeling - the process of building complex 3D models of body parts through a computer imaging process which allows ... the scientific discipline of building advanced mathematical models of biochemical systems thanks to advances in computer power ...

https://en.wikipedia.org/wiki/Biomodeling

Soyer OS, Salathé M, Bonhoeffer S (January 2006). "Signal transduction networks: topology, response and biochemical processes ... Steroids are also broken down by some bacteria in a process similar to beta oxidation, and this breakdown process involves the ... The metabolism of a cell achieves this by coupling the spontaneous processes of catabolism to the non-spontaneous processes of ... This process is often coupled to the conversion of carbon dioxide into organic compounds, as part of photosynthesis, which is ...

https://en.wikipedia.org/wiki/Metabolism

15 kDa plays other roles in immunological processes, such as in antigen-presenting cell maturation and in immune cell migration ... Biochemical Pharmacology. 59 (4): 317-320. doi:10.1016/S0006-2952(99)00177-X. PMID 10644038. Donlon TA, Krensky AM, Clayberger ... Peña SV, Hanson DA, Carr BA, Goralski TJ, Krensky AM (March 1997). "Processing, subcellular localization, and function of 519 ( ...

https://en.wikipedia.org/wiki/GNLY

A fed-batch process is the most common way to decrease the effects of substrate inhibition. Fed-batch processes are ... Biochemical Engineering Journal. 30 (2): 174-183. doi:10.1016/j.bej.2006.03.006. ISSN 1369-703X. Maduka, Chinonye Medline; ... The most common solution is to change the growth from a batch process to a fed-batch process. Other methods to overcome ... A fed-batch process will also have an output flow rate of the substrate/cell/product mixture which can be collected to retrieve ...

https://en.wikipedia.org/wiki/Substrate_inhibition_in_bioreactors

The assembly of 19S lid is independent to the assembly process of 19S base. Two assembly modules, Rpn5-Rpn6-Rpn8-Rpn9-Rpn11 ... Biochemical and Biophysical Research Communications. 396 (4): 1048-53. doi:10.1016/j.bbrc.2010.05.061. PMID 20471955. Tomko RJ ... An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The gene PSMD7 ... To meet such complicated demands in biological process via spatial and temporal proteolysis, protein substrates have to be ...

https://en.wikipedia.org/wiki/PSMD7

Her research has contributed significantly to the development of anticancer drugs and understanding the differentiation process ... in Biochemical Journal Glyoxalase III from Escherichia coli a single novel enzyme for the conversion of methylglyoxal into D- ... lactate without reduced glutathione (1995) in Biochemical Journal Methylglyoxal : From a putative intermediate of glucose ...

https://en.wikipedia.org/wiki/Manju_Ray

Lai MC, Lin RI, Tarn WY (May 2003). "Differential effects of hyperphosphorylation on splicing factor SRp55". The Biochemical ... "Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1". Molecular Cell. 6 (2): 307-16 ...

https://en.wikipedia.org/wiki/SFRS6

Extensive morphological and biochemical changes during apoptosis ensure that dying cells leave minimal impact on neighboring ... Apoptosis is the programmed destruction of cells, and the DNA molecules within them, and is a highly regulated process. These ... proteins are required for a cell to begin the apoptotic process "Destruction" proteins do things such as digest DNA in a dying ... and biochemical hallmark, of apoptosis. Apoptosis involves the activation of endonucleases with subsequent cleavage of ...

https://en.wikipedia.org/wiki/Fragmentation_(cell_biology)

Nieman LK (October 2015). "Cushing's syndrome: update on signs, symptoms and biochemical screening". European Journal of ... whether due to medication or internal processes. Some sources however do not consider the glucocorticoid medication-induced ...

https://en.wikipedia.org/wiki/Cushing's_syndrome

Unconfirmed results suggested that the combination of interferon and an antiviral agent may speed the healing process compared ... Biochemical and Biophysical Research Communications. 432 (3): 425-30. doi:10.1016/j.bbrc.2013.01.132. PMID 23415865. Navratil V ... while the immunoproteasome processes these peptides for loading onto the MHC I molecule, thereby increasing the recognition and ...

https://en.wikipedia.org/wiki/Interferon

... or genome annotation is the process of identifying the locations of genes and all of the coding regions in a ... biochemical function biological function involved regulation and interactions expression These steps may involve both ... Scientists are still at an early stage in the process of delineating this parts list and in understanding how all the parts " ... a process called gene prediction attaching biological information to these elements Automatic annotation tools attempt to ...

https://en.wikipedia.org/wiki/DNA_annotation

In retaliation, Aguja unleashes a massive force field in an attempt to kill her foes, killing herself in the process. The trio ... Serafina is also able to detect genetic and bio-chemical data down to the molecular level. This makes her an extraordinary ... therefore creating in the process the Children of the Vault. After Serafina's capture and escape from Orchis and the rise of ... created by a scientist and then cycled through normal evolutionary processes over the course of 6,000 years inside a time- ...

https://en.wikipedia.org/wiki/Children_of_the_Vault

Broadwell RD, Balin BJ (December 1985). "Endocytic and exocytic pathways of the neuronal secretory process and trans-synaptic ... Biochemical and Biophysical Research Communications. 377 (1): 35-40. doi:10.1016/j.bbrc.2008.09.077. PMID 18823949. (CS1: long ... in order to examine the brain areas involved in viscero-sensory processing. Another study used HSV type1 and type2 to ... Both the anterograde and retrograde tracing techniques are based on the visualization of the biological process of axonal ...

https://en.wikipedia.org/wiki/Anterograde_tracing

In most cells, Ca2+ channels regulate a wide variety of biochemical processes due to their role in controlling intracellular ...

https://en.wikipedia.org/wiki/Voltage-gated_ion_channel

April 1998). "Determination of functional domains in polypyrimidine-tract-binding protein". The Biochemical Journal. 331 (Pt 1 ... These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of ...

https://en.wikipedia.org/wiki/PTBP1

Biocon Biochemicals of Ireland was acquired from Leslie Auchincloss by Unilever in 1989.: 50 The partnership with Unilever ... built a new plant featuring proprietary solid substrate fermentation technology based on a semi-automated tray culture process ... After a brief period as a trainee manager at Biocon Biochemicals Limited, of Cork, Ireland, to learn more about the business, ... the founder of Biocon Biochemicals Limited, of Cork, Ireland. Auchincloss's company produced enzymes for use in the brewing, ...

https://en.wikipedia.org/wiki/Kiran_Mazumdar-Shaw

In general, most biochemical reactions are stereoselective, so only one stereoisomer will produce the intended product while ... Racemization can occur through some of the following processes: Substitution reactions that proceed through a free carbocation ... The stereoselective nature of most biochemical reactions meant that different enantiomers of a chemical may have different ...

https://en.wikipedia.org/wiki/Racemization

Concept URL: http://www.eionet.europa.eu/gemet/concept/812 ...

https://www.eionet.europa.eu/gemet/en/concept/812

Knowledge about biochemical or chemical process technologies. *Apply methods for sizing selected process operations or be able ... Course - Design of Sustainable Chemical and Biochemical processes, Project - TKP4171. course-details-portlet. ... One is a project work by groups of 3-4 students per group with the objective to design a chemical or biochemical process ... Groups of 3-4 students are assigned a problem to design a chemical or biochemical process. Several of the scientific personnel ...

https://www.ntnu.edu/studies/courses/TKP4171/

Biochemicals do not so much come into the process as they are the process, having a prominent role in the identity, purity, and ... Upstream processing and biochemicals. BioPharm: Where do biochemicals come into the pharma development and manufacturing ... Experts reveal how to identify the "right" biochemical, the process of sourcing biochemicals, sourcing challenges, and what ... Culture/FermentationContinuous ProcessingDrug DeliveryFill/FinishFormulationProcess ChromatographyProcess Control/PATProcess ...

https://www.biopharminternational.com/view/upstream-processing-biochemicals-and-raw-materials

HUMAN OSTEOSARCOMA (HOS TE-85) CELLS UNDERGO AN APOPTOTIC PROCESS THAT IS INHIBITED BY IGF-1 Mark E. Nuttall; Mark E. Nuttall ... Mark E. Nuttall, Maxine Gowen; HUMAN OSTEOSARCOMA (HOS TE-85) CELLS UNDERGO AN APOPTOTIC PROCESS THAT IS INHIBITED BY IGF-1. ...

https://portlandpress.com/biochemsoctrans/article-abstract/24/4/555S/93802/HUMAN-OSTEOSARCOMA-HOS-TE-85-CELLS-UNDERGO-AN?redirectedFrom=PDF

Finally, the process will be scaled up, initially to several litres and subsequently to plant-scale with a view to having a ... Other methods will be examined to improve the process such as recycling of the enzymes. The proteins will be purified to see if ... Selective decarboxylation of the product keto-acid in the transaminase process will allow us to obtain much higher yields and ... process that is suitable for the commercial production of novel L-amino acids. ...

https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=DT/E010822/1

Biochemical Processes. NREL is advancing processes that use enzymes, microbes, and catalysts to deconstruct and upgrade biomass ... Combined with process and catalyst innovations at partner universities and labs, NRELs deacetylation and mechanical refining ... NREL has developed a novel fermentation process to upgrade biomass sugars into 2,3-butanediol, a precursor for low-emission SAF ... NREL scientists and partners are scaling a biorefining process that upgrades wet waste into sustainable aviation fuel both ...

https://www.nrel.gov/bioenergy/net-zero-emission-biofuels.html

The preanalytic phase of the testing process generally encompasses test selection and ordering; specimen collection, processing ... Biochemical Genetic Test Reports. Biochemical genetic test reports should include the following more specific information to ... Biochemical Genetic Testing. In addition to meeting the CLIA test request requirements, laboratories that perform biochemical ... Biochemical Genetic Testing. Laboratories that perform biochemical genetic testing should have procedures in place to address ...

https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6102a1.htm

Studierende, welche sich für andere Vertiefungen (Wahlpflichtmodule) interessieren, können auch an den weiteren Vertiefungsveranstaltungen teilnehmen. Bitte beachten Sie aber die Teilnahmevorraussetzungen einzelner Veranstaltungen!. ...

https://www.dyn.bci.tu-dortmund.de/cms/en/teaching/biochemical-engineering/master-biw/index.html

The study differentiated between general (i.e. monetary) and food related anticipatory reward processing. We recruited a sample ... The study differentiated between general (i.e., monetary) and food-related anticipatory reward processing. We recruited a ... provide evidence that mesolimbic brain regions underlie both general as well as food-related anticipatory reward processing. In ... provide evidence that mesolimbic brain regions underlie both general as well as food related anticipatory reward processing. In ...

https://www.frontiersin.org/articles/10.3389/fnbeh.2014.00359/full

"Even patients over 70 still have a clear biochemical PFS advantage. The clinical PFS results are similar, but those with ... "We know that when these patients had immediate postoperative radiotherapy, they do better, and had a longer biochemical [PFS] ... "When we look at baseline factors and biochemical PFS, all groups benefited. Patients with positive surgical margins and with ... At 10 years, 60.6% of patients who received postoperative radiotherapy showed biochemical PFS compared with 41.1% of the wait- ...

https://www.medscape.com/viewarticle/739945

Biochemicals - 1st Edition. Print Book & E-Book. ISBN 9780323906333, 9780323998154 ... Chapter 14 Hybrid technologies for enhanced microbial fermentation process for production of bioenergy and biochemicals ... Biomass, Biofuels, Biochemicals. Holiday Sale. :. Save up to 25% on print and eBooks with FREE shipping. No promo code needed. ... We cannot process tax exempt orders online. If you wish to place a tax exempt order please contact us. ...

https://www.elsevier.com/books/biomass-biofuels-biochemicals/zhang/978-0-323-90633-3

2.1.2 Biochemical-related predictors. Sedimentary biochemical processes directly influence the bottom DO consumption rate. ... It suggests that at the first stage of hypoxia development in late spring and early summer, sedimentary biochemical processes ... Both water stratification and bottom biochemical processes modulate the variability in bottom DO concentration in the LaTex ... However, global forecast models such as HYCOM do not cover biochemical parameters. Therefore, the biochemical-related term SOC ...

https://bg.copernicus.org/articles/19/3575/2022/

Seed priming with KNO3 mediates biochemical processes to inhibit lead toxicity in maize (Zea mays L.). ... Seed priming with KNO,sub,3,/sub, mediates biochemical processes to inhibit lead toxicity ...

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-28369913

1 Process Engineer Biochemicals / Pharmaceuticals jobs available on The Chemical Engineer Job Board. Apply or sign up for job ... The company recently expanded process development labs and manufacturing capacity in the North West and the organisation is ...

https://jobs.thechemicalengineer.com/jobs/?categories%5B%5D=Biochemicals%20%2F%20Pharmaceuticals&categories%5B%5D=Food%20%26%20Drink&categories%5B%5D=Industrial%20Gases&job_type%5B%5D=Process%20Engineer&salary=6

... biochemical ... process ...

https://ki.se/en/research/never-too-late-to-start-exercising

Nanotechnology; Chemical-composition; Chemical-properties; Toxicology; In-vitro-studies; In-vivo-studies; Biochemical-analysis ... researchers can tailor the structure of CNMs to either promote or inhibit these processes. In nanomedical applications such as ... and their oxidation/biodegradation processes as catalyzed by peroxidase enzymes. We also communicate our current understanding ... Biodegradation; Biohazards; Oxidative-enzymes; Oxidative-processes; Peroxidases; Enzymatic-effects; Enzyme-activity; Enzymes; ...

https://www.cdc.gov/niosh/nioshtic-2/20041801.html

Yet natural membranes are also dynamically remodeled in multiple cellular processes. Here, we show that synthetic amphiphile ... is associated with the reconstitution of dynamic processes. Natural membranes not only segregate biochemical reactions and ... En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes. *Lado Otrin. ORCID: orcid.org/0000 ... Otrin, L., Witkowska, A., Marušič, N. et al. En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid ...

https://www.nature.com/articles/s41467-021-25294-z?error=cookies_not_supported&code=e5febcca-f930-4651-a419-d848a579a9dd

Biochemical function: * not assigned Biological process: * not assigned Cellular component: * not assigned ...

https://www.ebi.ac.uk/pdbe/entry/pdb/1aqa

Supercritical fluids: an interesting medium for chemical and biochemical processes journal, September 1997 * Ikushima, Y. ... Process for production of esters for use as a diesel fuel substitute using a non-alkaline catalyst patent, June 1996 * Basu, ... Process for the production of fatty acid alkyl esters patent, June 2002 * Haas, Michael; Bloomer, Scott; Scott, Karen M. ... Process for the pre-esterification of free fatty acids in fats and oils patent, October 1987 * Jeromin, Lutz; Peukert, Eberhard ...

https://www.osti.gov/doepatents/biblio/1245978

Characterization of biochemical processes and structures. Genetic modification of such processes and structures through ... Emphasis on these processes in embryonic cells as well as in specialized cell types of the immune and nervous systems.. ... Topics include biochemical properties, virus-host interaction, productive cycle, effect of virus on host cell and organism, ... to industrial processes.. Lectures, 3 hours per week; lab, 3 hours per week for six weeks.. Restriction: students must have a ...

https://brocku.ca/webcal/2019/undergrad/biol.html?view=printable

Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes. Journal of ... To understand underlying mechanisms, we identified subcellular processes (SCPs) composed of one or more biochemical pathways ... A quantitative understanding of the key processes driving EBOV assembly and budding could provide valuable insights to inform ... The recognition of carbohydrates by lectins plays key roles in diverse cellular processes such as cellular adhesion, ...

https://www.jbc.org/Computational-Biology?startPage=&Ppub=%5B20201124%20TO%2020221124%5D

Analytical-processes; Metal-compounds; Biochemical-tests; Metabolites; Performance-capability; Equipment-reliability; Testing- ...

http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=battelle&f1=%2A&Startyear=&Adv=0&terms=1&EndYear=&Limit=10000&sort=&D1=10&PageNo=5&RecNo=48&View=f&

Sample Collection and Processing. Blood Sample for Hematological and Biochemical Examination. Blood samples were collected from ... Biochemical Findings. The mean values with the serum biochemical parameters, including total protein, albumin, aspartate ... The hematological and biochemical means were compared between groups of animals by using the t-test (mean comparison test) at 5 ... You can learn about what data of yours we retain, how it is processed, who it is shared with and your right to have your data ...

https://www.dovepress.com/a-comparative-study-on-pathological-changes-in-the-small-intestine-of--peer-reviewed-fulltext-article-VMRR

Analysis of Cell Biochemical Processes from First Principles to Cytometry Duration: 1 hour 3 minutes 9 seconds Cell cycle ... Advanced Process Quality Control and Outlier Detection with Discrete Particle Analysis Duration: 47 minutes 29 seconds Avanced ... Particle Size and Associated Sedimentary Processes on Wetland Gain and Loss in the Mississippi River Delta Duration: 1 hour 3 ... Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy Duration: 46 minutes ...

https://www.beckman.com/resources/videos/webinars

HGPRT catalyzes a biochemical process called purine salvage. Purines are used to make DNA and RNA-the stuff of genes and ...

https://wwwnc.cdc.gov/eid/article/11/2/04-0767_article

Although both processes increase with rising water temperatures, oxygen depletion due to BOD oxidation increases faster than ... the impact of rising water temperature on biochemical oxygen demand (BOD) assimilative capacity depends on the interplay of two ... Biochemical process equations. Water Sci. Technol. 2001, 43, 329-338. [Google Scholar] [CrossRef] ... Specifically, rising temperatures have a greater effect on the biochemical processes that deplete oxygen than on the ...

https://www.mdpi.com/2073-4441/13/17/2408?utm_campaign=releaseissue_waterutm_medium=emailutm_source=releaseissueutm_term=doilink21

Biochemical Society Company no. 00892796. *Registered Charity no. 253894. *VAT no. GB 523 2392 69 ... Unique features of selenocysteine incorporation function within the context of general eukaryotic translational processes A.L. ... This machinery includes the elements involved in transcription, mRNA splicing and transport, and translational processes. Many ... Unique features of selenocysteine incorporation function within the context of general eukaryotic translational processes. ...

https://port.silverchair.com/biochemsoctrans/article-abstract/33/6/1493/65497/Unique-features-of-selenocysteine-incorporation?searchresult=1

Consequently, to speed up the next generation of processes, innovators need to start considering how to improve process R&D at ... As a product class, its still in its infancy and there are a number of process improvements that can be made to the production ... I am confident that the next generation of ADCs will be manufactured through a more efficient and streamlined set of processes ... Process innovation needs to be undertaken in early R&D phase, predicts ADC Bio ...

https://www.chemicalsknowledgehub.com/news/process-innovation-needs-to-be-undertaken-in-early-rd-phase-predicts-adc-bio/

We sought to identify the many different biochemical pathways that contribute to this whole cell response. (jbc.org)
To understand underlying mechanisms, we identified subcellular processes (SCPs) composed of one or more biochemical pathways and their interactions required for this response. (jbc.org)
Dr Manos Karteris and Prof Amanda Harvey will then explore Biochemical Pathways to Fertility . (brunel.ac.uk)
This will offer a biochemical view of the molecules, vitamins, hormones and pathways that lead to fertility, those that can be used to enhance fertility and protect the health of a developing foetus. (brunel.ac.uk)
The company, a spin-out of ETH Zurich and the Paul Scherrer Institute, Switzerland, uses high throughput biochemical screening of compounds integrated into an artificial intelligence and cell pathways mathematical modeling process. (wspa.com)
however, the final common pathways to depression involve biochemical changes in the brain. (medscape.com)

It includes acceleration and inhibition of physiological and biochemical processes and other pharmacologic mechanisms of action. (bvsalud.org)
Although a variety of physiological and biochemical processes have been found to be vanadium sensitive, the book concludes that all studies reporting an association between vanadium and disease suffer from serious methodological flaws. (who.int)

Microbial Fermentation of Biowastes summarizes new advances in the development of various strategies for enhanced microbial fermentation for organic waste conversion to bioenergy/biochemicals, and for biodegradation of plastic waste. (elsevier.com)
The ex vitro, in vitro, and in vivo data presented in this Account provide fundamental insights into the biopersistence of CNMs, such as carbon nanotubes and graphene, and their oxidation/biodegradation processes as catalyzed by peroxidase enzymes. (cdc.gov)
For example, armed with an understanding of how and why CNMs undergo enzyme-catalyzed oxidation and biodegradation, researchers can tailor the structure of CNMs to either promote or inhibit these processes. (cdc.gov)
An improved understanding of the fuel biodegradation process also has the potential to benefit bioremediation. (rsc.org)

New quantum tool developed in groundbreaking experimental achievement Monday, November 21, 2022 En Français Scientists recreate properties of light in neutral fundamental particles called neutrons For the first time in experimental history, researchers at the Institute for Quantum Computing (IQC) have created a device that generates twisted neutrons with well-defined orbital angular momentum. (uwaterloo.ca)

ProPlantStress focused on a specific biochemical mechanism termed proteolytic processing. (europa.eu)
ABSTRACT The aim of the study was to assess the accuracy of some specific biochemical indicators in discriminating between Helicobacter pylori-associated gastritis and H. pylori-associated stomach cancer (serum gastrin level, serum soluble E-cadherin and tissue COX-2 activity, as well as serodiagnostic markers for H. pylori infection) in order to find a simple diagnostic test that can reasonably predict the development of gastric cancer. (who.int)

Current experiments are aimed at defining additional Frizzled-regulated processes and elucidating the molecular mechanisms and cell biologic results of Frizzled signaling within these various contexts. (hopkinsmedicine.org)
This chemistry must provide mechanisms that allow cells to interact with the external world, a means to power the cell, machinery to carry out varied processes within the cell, a structure within which everything runs, and also governance through a web of interlocking chemical reactions. (biggerbooks.com)
Overall, the dynamic metabolic model serves as a powerful tool to aid laboratory experiments, providing savings in time, money, and resources, as well as an improved understanding of the biochemical mechanisms driving the processes. (tufts.edu)
A newly published investigation of molecular and biochemical mechanisms revealed that CADs are injurious to human cells, not to the virus. (faegredrinker.com)

Succinate synthase enzymes, which belong to the glycyl radical enzyme family, are the main facilitators of these biochemical reactions. (rsc.org)
Eventually, personalized medicine will be further informed by detailed understanding of the body's distinct repertoire of proteins (proteomics) and complete catalog of biochemical reactions (metabolomics). (engineeringchallenges.org)
Biochemistry is the study of those reactions, the molecules that are created, manipulated, and destroyed as a result of them, and the massive macromolecules (such as DNA, cytoskeletons, proteins and carbohydrates) that form the chemical machinery and structures on which these biochemical reactions take place. (biggerbooks.com)
The chemical nature, order, and biochemical mechanism of all the oxygenative tailoring reactions has remained enigmatic despite the identification of the biosynthetic gene cluster and the use of targeted-gene deletion experiments. (cdc.gov)

The results demonstrate that the HSV1 recombinant vector expressing the fulllength CRH precursor molecule constitutes an excellent delivery system for both cell lines and postmitotic neurons in vitro, which has enabled the study of targeting, endoproteolytic processing and biological activity of this neuropeptide precursor. (semanticscholar.org)
The results demonstrate that the HSV1 recombinant vector expressing the full-length CRH precursor molecule constitutes an excellent delivery system for both cell lines and postmitotic neurons in vitro, which has enabled the study of targeting, endoproteolytic processing and biological activity of this neuropeptide precursor. (semanticscholar.org)
Mesoscopic kinetics: Stochastic chemical processes, description of stochastic biological systems with Master equations. (uu.se)
It is inescapable to understand biological processes, test potential drugs, assess toxicity of chemical compounds, and multiply cells for cell therapy. (grstiftung.ch)
The coating does not interfere with conventional biological techniques to retrieve cells for biochemical or molecular analysis. (grstiftung.ch)
In these situations, an assay measuring a real biological process may still show a phenotype of interest under some conditions that can be observed and measured even if positive controls that induce high levels of cells with the phenotype do not exist. (nih.gov)

NREL researchers are developing processes to convert widely available biomass and waste feedstocks into sustainable biofuels that reduce greenhouse gas (GHG) emissions by at least 100% compared to petroleum-based fuels. (nrel.gov)
The sponsored projects undertaken by the centre include Unnat Bharat Abhiyan, Participatory Forest Management Project, Tribal Development Project, Integrated Rural Energy Planning, Agro-Climatic Regional Planning, Lignocellulosics based liquid and gaseous biofuels (bioethanol, biobutanol, biomethane, biodiesel) and by-product utilization leading to zero-wastes process/product development. (iitkgp.ac.in)

The technology could help process standing dead wood biomass in California that has led to forest fire outbreaks, as well as emerging agricultural crops in the Midwest that sink carbon into the soil for large GHG reductions. (nrel.gov)
NREL has developed a novel fermentation process to upgrade biomass sugars into 2,3-butanediol, a precursor for low-emission SAF hydrocarbons. (nrel.gov)
NREL is advancing processes that use enzymes, microbes, and catalysts to deconstruct and upgrade biomass into sugar-derived intermediates for upgrading into renewable fuels. (nrel.gov)

Here we present a discrete mathematical model for the human sperm AR, based on the biophysical and biochemical interactions among some of the main components of this complex exocytotic process. (biorxiv.org)
Although its etiology remains unclear, several events in PE physiopathology are well studied and can be evaluated using biochemical or biophysical methods. (hindawi.com)

The ensemble model combines a zero-inflated Poisson generalized linear model (GLM) and a quasi-Poisson generalized additive model (GAM) and considers predictors with hydrodynamic and biochemical features. (copernicus.org)

Chemical processes occurring in living organisms. (europa.eu)

BS/MS/PhD in Biochemical Engineering, Chemical Engineering, Science or Biotechnology. (nih.gov)

The effects of handling processes were investigated in the mud crab, Scylla serrata, using pre-cooling and chelae tying during emersion storage.Muscle glycogen, muscle lactate, muscle yield, muscle pH, volatile basic nitrogen (VBN), and chemical composition were analyzed. (buu.ac.th)
Changes or alterations in biochemical composition take place due to various reasons viz. (org.in)
This can alter the function of other genes, with unknown consequences to biochemical composition and function. (gmwatch.org)
These mutations can affect the functioning of many genes, leading to alterations in the plant's protein and biochemical composition. (gmwatch.org)

TBT4140 Biochemical Engineering, TBT4146 Molecular Genetics and TBT4110 Microbiology (or similar) must be passed and you need to have a general knowledge of process engineering. (ntnu.edu)
Processing of procorticotropin-releasing hormone (pro-CRH): molecular forms of CRH in normal and preeclamptic pregnancy. (semanticscholar.org)
We use gene manipulation in the mouse, cell culture models, and biochemical reconstitution to investigate the relevant molecular events underlying these processes, and to genetically mark and manipulate cells and tissues. (hopkinsmedicine.org)
Genetic variability and genetic differentiation in two Ovis species--domesticated (Askanian sheep, Sokilska and Kulunda sheep) and wild (bighorn sheep) were analyzed using different types of molecular-genetic markers--genetic-biochemical (30 loci) and DNA (ISSR-PCR) ones. (cytgen.com)

Optimisation of emulsion copolymerization of Styrene and MMA in batch and semi-batch reactors, Chemical Product and Process Modeling, 6 . (psenterprise.com)
While contributing towards accelerated process development, representative process models enable advanced optimisation of process parameters, thus having a tangible impact on the assurance of product quality and manufacturing robustness. (approcess.com)

D: Somogyi L.P., Ramaswamy H.S. , Hui Y.H.(1996): Processing Fruits: Science and Technology, Volume 1, Biology principles and applications, Technomic, ISBN1-56676-362-2. (vscht.cz)

ADC Biotechnology predicts that the next crucial phase of innovation to optimize and streamline production processes of Antibody Drug Conjugates (ADCs) will be designed at the clinical development stage by specialist, ADC focused service providers. (chemicalsknowledgehub.com)
White biotechnology-also known as industrial biotechnology-uses microorganisms and enzymes to produce chemical and biochemical products. (basf.com)

In addition, the book reviews progress in the conversion of common wastes to bioenergy and biochemicals via enhanced anaerobic digestion, also summarizing the significant progress achieved on enhancing anaerobic digestion via additive strategy, multi-stage bioreactor strategy, microbial bioaugmentation strategy, genetic engineering approach, and much more. (elsevier.com)

Additionally, we will examine a series of decarboxylase enzymes for their activity and suitability as enzyme partners in the biotransformation process. (ukri.org)
Other methods will be examined to improve the process such as recycling of the enzymes. (ukri.org)

mediates biochemical processes to inhibit lead toxicity in maize (Zea mays L. (bvsalud.org)

Apply methods for sizing selected process operations or be able to look-up and apply such methods. (ntnu.edu)
Similarly, we have applied these methods to define sequence specificity and in vivo substrates of selected proteases that literature data suggested to play important roles in these processes. (europa.eu)
Often, using new biotechnological methods and processes allows us to manufacture these products more efficiently and with lower resource consumption than with conventional processes. (basf.com)
Turbo Vacuum realizes that Mass Spectrometric measuring methods have become an indispensable diagnostic aid in numerous branches of process engineering, technology and product development, medicine, and basic scientific research. (turbovacuum.com)

The course will have a focus on the design of sustainable processes for the future, being more efficient with respect to the utilization of energy and material. (ntnu.edu)

The uniqueness of the Vivostat ® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF ® ) without using cryoprecipitation and without the need for a separate thrombin component. (globalregenerative.trade)

Previous studies consistently found overweight and obesity to be related to alterations in neural food reward processing ( Burger and Stice, 2011 ). (frontiersin.org)

Experimentally, we are performing biochemical probing experiments to understand the process of switching and the effect of ligand and magnesium on this process. (lanl.gov)
Execute cell culture based experiments utilizing novel technologies to improve platform processes such as automation and non-viral transduction strategies. (nih.gov)

Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. (cdc.gov)
Laboratories that perform biochemical genetic testing are required by CLIA regulations to meet the general quality systems requirements for nonwaived testing and the personnel requirements for high-complexity testing. (cdc.gov)
As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. (cdc.gov)
These recommendations are intended for laboratories that perform biochemical genetic testing to improve the quality of laboratory services and for newborn screening laboratories to ensure the quality of laboratory practices for inherited metabolic disorders. (cdc.gov)
These recommendations also are intended as a resource for medical and public health professionals who evaluate laboratory practices, for users of laboratory services to facilitate their collaboration with newborn screening systems and use of biochemical genetic tests, and for standard-setting organizations and professional societies in developing future laboratory quality standards and practice recommendations. (cdc.gov)
In Chapter 4, further application of the model is demonstrated by simulating the metabolic responses of genetic modulations (e.g. up- or down-regulation), independently, but more importantly, in conjunction with process variable changes. (tufts.edu)
Optimal operating conditions for both process and genetic variables are determined for producing improved quantity and quality of recombinant protein. (tufts.edu)
Regulation must start from consideration of the genetic engineering process used to create the gene-edited organism ("process-based regulation"), so that regulators know where things can go wrong and what to look for. (gmwatch.org)

For anabolic processes (conversion of small molecules into large), BIOSYNTHESIS is used. (bvsalud.org)

CONCLUSIONS Novel data relating ODC activation and polyamine concentrations to neuropathology is presented indicating that high ODC activity represents a biochemical marker of malignancy in brain tumours. (bmj.com)

For rivers and streams, the impact of rising water temperature on biochemical oxygen demand (BOD) assimilative capacity depends on the interplay of two independent factors: the waterbody's dissolved oxygen (DO) saturation and its self-purification rate (i.e., the balance between BOD oxidation and reaeration). (mdpi.com)
Industrial and manufacturing processes may require pre-treatment of waste water if limits of BOD (Biochemical Oxygen Demand) are exceeded. (cityofalliance.net)

The purpose was to investigate whether the content of the polyamines putrescine, spermidine, and spermine, and the activity of the first metabolic key enzyme of polyamine metabolism, ornithine decarboxylase (ODC), represent biochemical markers of malignancy in brain tumours. (bmj.com)
8-11 It has been demonstrated that polyamines might be useful biochemical markers for diagnosis and follow up in patients with malignant neoplasms. (bmj.com)
The average heterozygosity of biochemical markers loci was in range of 0.073-0.188. (cytgen.com)
Markers involved into process of genofond divergence of two closely related species were revealed. (cytgen.com)

A quantitative understanding of the key processes driving EBOV assembly and budding could provide valuable insights to inform drug development. (jbc.org)

How do you define current good manufacturing practices (CGMP), specifically as it relates to biochemicals? (biopharminternational.com)
What are best practices for sourcing biochemicals? (biopharminternational.com)
The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)

Researchers in the fields of waste treatment, environmental engineering, and biochemical engineering. (elsevier.com)
Dynamic simulation of liquid polymerization reactors in Sheripol process for polypropylene, Journal of Industrial and Engineering Chemistry , 33, 298-306. (psenterprise.com)
Biochemical Engineering Journal , 191 , 108763. (approcess.com)
Biochemical Engineering Journal , 69. (plymsea.ac.uk)
Biochemical Engineering Journal , 54. (plymsea.ac.uk)

Carer support grants are only available for Biochemical Society Scientific Meetings, Training Events or Courses. (biochemistry.org)

Researchers are scaling the process, performing techno-economic and life cycle analysis to understand barriers to bringing the technology to the market. (nrel.gov)
We've shown that, after 5 years in a former analysis, there was a definite advantage for patients with immediate adjuvant radiotherapy with respect to the biochemical progression-free survival [PFS] and local relapses. (medscape.com)
The EORTC study involved 1005 patients enrolled between 1992 and 2001, and the first 5-year analysis showing a significant difference in clinical and biochemical PFS was published in The Lancet (Bolla et al. (medscape.com)
Blood was collected for hematological and serum biochemical analysis. (dovepress.com)
Biochemical analysis and histopathological classification were carried out in serial tumour samples. (bmj.com)
The Prisma Series for residual gas analysis, leak detections and process - monitoring in the high vacuum range. (turbovacuum.com)

The documents describe specific timelines for producing biochemical weapons and include a bar graph depicting the parallel processes that must take place between Days 1 and 31 of manufacture. (asyura2.com)

Sometimes, analytical support is available from the same vendor-an ELISA (enzyme-linked immunosorbent assay), for example-to show clearance in your process. (biopharminternational.com)
Thus, you are often evaluating both the utility of the biochemical in your process and your analytical ability to demonstrate removal in the process. (biopharminternational.com)

In addition, we have collaborated with several plant science groups across Europe to teach visiting researchers in our methodology and to investigate protease function and proteolytic processes under different stress conditions and in additional plant-microbe interactions, including economically important crop species. (europa.eu)

These metabolism boosters (or Metabolic Booster Supplements) are natural products enhancing the body's natural metabolic process, promoting the loss of unnecessary body weight and establishing the stabilization of the individual's weight at normal (and safe for his health) levels. (villagevoice.com)
Our main mission is supporting and accelerating the healing process following medical treatment by enhancing the body's own capabilities. (globalregenerative.trade)

Application of the model is the demonstrated by predicting the effect of process variable changes (e.g. temperature, seed density, nutrient concentrations) on the resulting metabolic dynamics of a CHO fed-batch culture. (tufts.edu)

Correlation of regional biochemical and histomorphological data in rapidly growing neoplasms showed high enzyme activity in solid tumour parts and low activity in necrotic areas. (bmj.com)

For upstream processing, the cell line dictates the mode in which we run the upstream process. (biopharminternational.com)
Thus, having the right producer cell for our lentiviral process can really make or break process performance-and, by extension, our ability to intensify the process to commercially-relevant scale. (biopharminternational.com)
Biochemicals often make up such intrinsic components of the process (plasmids, cell line, etc. (biopharminternational.com)
3-5 Their biosynthesis is closely associated with cellular growth processes, including physiological 3 4 6 7 and neoplastic cell proliferation. (bmj.com)
The flow of these ions creates an electrical charge across the cell membrane, which affects certain biochemical processes. (medlineplus.gov)
These abnormalities overactivate a biochemical process that increases adrenal cell growth and division (proliferation), which promotes adenoma formation. (medlineplus.gov)
Cell culture is the process of taking cells out of the body and growing them in an artificial environment. (grstiftung.ch)
In a nutshell, the cell original/natural characteristics were maintained even throughout long-term cell culture process. (grstiftung.ch)
Drugs and therapies all aim to modify biochemical processes for good or ill: Penicillin, derived from mould, stops bacteria making their cell walls. (biggerbooks.com)
Perform studies to scale-up CAR T manufacturing processes based on the gamma delta T cell platform using the Xuri and Sartorius bioreactors. (nih.gov)

R: Felows P. J. (2009): Food processing technology : principles and practice, 3rd ed. (vscht.cz)

When we refer to CGMP for biochemicals, we would expect suppliers to adhere to GMP requirements in the manufacturing, documentation, testing, release, and distribution of those materials. (biopharminternational.com)
Product categories of Biochemicals , we are specialized manufacturers from China, Sitosterol Phytosterol , Plant Sitosterol suppliers/factory, wholesale high-quality products of Beta Sitosterol R & D and manufacturing, we have the perfect after-sales service and technical support. (chsurfactants.com)

D: Smith D.S., Cash J.N., Nip W.-K., Hui Y.H.(1997): Processing Vegetables: Science and Technology, Technomic, ISBN 1-56676-507-2. (vscht.cz)

Sourcing biochemicals adds a layer of complexity on top of an already complex process of sourcing raw materials. (biopharminternational.com)

Yet natural membranes are also dynamically remodeled in multiple cellular processes. (nature.com)

Where do biochemicals come into the pharma development and manufacturing process? (biopharminternational.com)
The company recently expanded process development labs and manufacturing capacity in the North West and the organisation is working with 7 of the top 10 pharma companies globally, as well as many leading smaller biotechs. (thechemicalengineer.com)
Through implementation of digital process models, a greater understanding of the intricate relationship between product quality attributes and manufacturing process performance may be established. (approcess.com)
The process industries have begun to realize value from data analytics and machine learning, following on the success experienced in other manufacturing fields. (aiche.org)

NREL scientists and partners are scaling a biorefining process that upgrades wet waste into sustainable aviation fuel both compatible with existing jet engines and capable of supporting net-zero-carbon flight. (nrel.gov)

The researchers are particularly interested in learning how a network in an insect's brain can build such an orientation memory and how exactly the related biochemical processes function. (uni-mainz.de)
Officers with higher post-traumatic stress disorder (PTSD) symptoms had a nearly two-fold reduction in brachial artery flow-mediated dilation, indicating greater impairment of endothelial function (physiologic dysfunction of the normal biochemical processes carried out by the cells which line the inner surface of blood vessels) than officers with fewer PTSD symptoms. (cdc.gov)
Moreover, normal pregnancy is characterized by an increase in endothelial function and a progressive reduction in the resistance of uterine vessels, due to the placentation process [ 19 ]. (hindawi.com)
The consequences are an alteration in the plant's protein and biochemical function, which could lead to poor crop performance and/or the production of novel toxins and allergens or higher levels of existing toxins and allergens. (gmwatch.org)

To apply knowledge of food processes, chemistry and technology to solve specific technological assignments. (vscht.cz)

From greenhouse gas emissions to process cost drivers to investment decision-making, NREL is analyzing the numerous economic, environmental, and social vectors that shape the deployment of net-zero-emission fuels. (nrel.gov)
They ensure homogenous mixing results, high process reliability, high efficiency, low operating costs and low environmental stress. (sulzer.com)

For many biochemicals, you not only have to evaluate the performance in your process but also how it will be characterized. (biopharminternational.com)

Anatomy24

Organisms15

Diseases3

Chemicals and Drugs83

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Phenomena and Processes82

Disciplines and Occupations5

Information Science6

Health Care2

The fractal geometry of nutrient exchange surfaces does not provide an explanation for 3/4-power metabolic scaling. (1/86)

Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model. (2/86)

Different types of cell-to-cell connections mediated by nanotubular structures. (3/86)

Solution NMR structure determination of proteins revisited. (4/86)

Astrocytes as the glucose shunt for glutamatergic neurons at high activity: an in silico study. (5/86)

Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. (6/86)

Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism. (7/86)

Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites. (8/86)

Biochemical Processes

Biochemistry

Biochemical Phenomena

Models, Biological

Models, Chemical

Computer Simulation

Kinetics

Molecular Sequence Data

Algorithms

Thermodynamics

Signal Transduction

Amino Acid Sequence

Models, Molecular

Temperature

Time Factors

Proteins

Escherichia coli

Mutation

Oxidation-Reduction

Cell Line

Cells, Cultured

Protein Binding

Base Sequence

Protein Structure, Tertiary

Sequence Homology, Amino Acid

Substrate Specificity

Recombinant Proteins

Cloning, Molecular

Phylogeny

Phenotype

Bacterial Proteins

Electrophoresis, Polyacrylamide Gel

Binding Sites

Sequence Alignment

Biological Markers

Microscopy, Electron

Crystallography, X-Ray

RNA, Ribosomal, 16S

Protein Conformation

DNA, Bacterial

Alkaline Phosphatase

Molecular Weight

Sequence Analysis, DNA

Membrane Proteins

DNA

Liver

Phosphorylation

Hydrogen-Ion Concentration

Species Specificity

DNA, Ribosomal

Saccharomyces cerevisiae

Cell Membrane

Adenosine Triphosphatases

Bacterial Typing Techniques

Metabolic Networks and Pathways

Catalytic Domain

Recombinant Fusion Proteins

Blotting, Western

Pregnancy-Associated Plasma Protein-A

Carrier Proteins

Prostatectomy

Adenosine Triphosphate

Fatty Acids

Structure-Activity Relationship

Enzymes

Dimerization

DNA-Binding Proteins

Saccharomyces cerevisiae Proteins

Prostatic Neoplasms

Hydrolysis

Catalysis

Amino Acids

Protein Structure, Secondary

Cattle

Calcium

RNA, Messenger

Plasmids

Prostate-Specific Antigen

DNA Primers

Peptides