Bioartificial organs. Medical search

Artificial organs that are composites of biomaterials and cells. The biomaterial can act as a membrane (container) as in BIOARTIFICIAL LIVER or a scaffold as in bioartificial skin.

Devices for simulating the activities of the liver. They often consist of a hybrid between both biological and artificial materials.

Devices intended to replace non-functioning organs. They may be temporary or permanent. Since they are intended always to function as the natural organs they are replacing, they should be differentiated from PROSTHESES AND IMPLANTS and specific types of prostheses which, though also replacements for body parts, are frequently cosmetic (EYE, ARTIFICIAL) as well as functional (ARTIFICIAL LIMBS).

Devices which can substitute for normally functioning KIDNEYS in removing components from the blood by DIALYSIS that are normally eliminated in the URINE.

A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.

Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)

The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.

Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.

Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.

Devices for simulating the activity of the pancreas. They can be either electromechanical, consisting of a glucose sensor, computer, and insulin pump or bioartificial, consisting of isolated islets of Langerhans in an artificial membrane.

Genetically developed small pigs for use in biomedical research. There are several strains - Yucatan miniature, Sinclair miniature, and Minnesota miniature.

Methods for maintaining or growing CELLS in vitro.

Water-soluble proteins found in egg whites, blood, lymph, and other tissues and fluids. They coagulate upon heating.

Methods of creating machines and devices.

A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.

Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.

Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.

The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.

Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.

The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Electrical devices that are composed of semiconductor material, with at least three connections to an external electronic circuit. They are used to amplify electrical signals, detect signals, or as switches.

Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.

Exclusive legal rights or privileges applied to inventions, plants, etc.

Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.

Large hospitals with a resident medical staff which provides continuous care to maternity, surgical and medical patients.

Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.

The transference of a complete HAND, as a composite of many tissue types, from one individual to another.

Transference of an organ between individuals of the same species or between individuals of different species.

Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.

A highly miniaturized version of ELECTROPHORESIS performed in a microfluidic device.

Reductions in all or any portion of the costs of providing goods or services. Savings may be incurred by the provider or the consumer.

Learning algorithms which are a set of related supervised computer learning methods that analyze data and recognize patterns, and used for classification and regression analysis.

Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.

Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.

Theory and development of COMPUTER SYSTEMS which perform tasks that normally require human intelligence. Such tasks may include speech recognition, LEARNING; VISUAL PERCEPTION; MATHEMATICAL COMPUTING; reasoning, PROBLEM SOLVING, DECISION-MAKING, and translation of language.

A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.

Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.

The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.

The normal length of time of an organism's life.

A subdiscipline of human genetics which entails the reliable prediction of certain human disorders as a function of the lineage and/or genetic makeup of an individual or of any two parents or potential parents.

The point at which religious ensoulment or PERSONHOOD is considered to begin.

A publication issued at stated, more or less regular, intervals.

X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.

The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

The profession concerned with the teeth, oral cavity, and associated structures, and the diagnosis and treatment of their diseases including prevention and the restoration of defective and missing tissue.

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

One of a set of bone-like structures in the mouth used for biting and chewing.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

Excitability and contractility of skeletal muscle engineered from primary cultures and cell lines. (1/58)

The purpose of this study was to compare the excitability and contractility of three-dimensional skeletal muscle constructs, termed myooids, engineered from C2C12 myoblast and 10T1/2 fibroblast cell lines, primary muscle cultures from adult C3H mice, and neonatal and adult Sprague-Dawley rats. Myooids were 12 mm long, with diameters of 0.1-1 mm, were excitable by transverse electrical stimulation, and contracted to produce force. After approximately 30 days in culture, myooid cross-sectional area, rheobase, chronaxie, resting baseline force, twitch force, time to peak tension, one-half relaxation time, and peak isometric force were measured. Specific force was calculated by dividing peak isometric force by cross-sectional area. The specific force generated by the myooids was 2-8% of that generated by skeletal muscles of control adult rodents. Myooids engineered from C2C12-10T1/2 cells exhibited greater rheobase, time to peak tension, and one-half relaxation time than myooids engineered from adult rodent cultures, and myooids from C2C12-10T1/2 and neonatal rat cells had greater resting baseline forces than myooids from adult rodent cultures. (+info)

Injectable gels for tissue engineering. (2/58)

Recently, tissue engineering approaches using injectable, in situ gel forming systems have been reported. In this review, the gelation processes and several injectable systems that exhibit in situ gel formation at physiological conditions are discussed. Applications of selected injectable systems (alginate, chitosan, hyaluronan, polyethylene oxide/polypropylene oxide) in tissue engineering are also described. Injectable polymer formulation can gel in vivo in response to temperature change (thermal gelation), pH change, ionic cross-linking, or solvent exchange. Kinetics of gelation is directly affected by its mechanism. Injectable formulations offer specific advantages over preformed scaffolds such as: possibility of a minimally invasive implantation, an ability to fill a desired shape, and easy incorporation of various therapeutic agents. Several factors need to be considered before an injectable gel can be selected as a candidate for tissue engineering applications. Apart from tissue-specific cell-matrix interactions, the following gel properties need to be considered: gelation kinetics, matrix resorption rate, possible toxicity of degradation products and their elimination routes, and finally possible interference of the gel matrix with histogenesis. (+info)

Tissue engineering strategies for adipose tissue repair. (3/58)

Tissue engineering is a relatively young field that combines engineering, clinical science, and life sciences to, in part, repair or regrow tissues. Adipose tissue has recently become a focus area for tissue engineering, encouraged by the large number of reconstructive, cosmetic, and correctional indications that could be addressed with clinically translatable adipose tissue engineering strategies. This review discusses the three aspects of an adipose construct, namely cell types, scaffold, and microenvironment, and presents current tissue engineering strategies under pursuit. (+info)

Tissue engineering in the cardiovascular system: progress toward a tissue engineered heart. (4/58)

Achieving the lofty goal of developing a tissue engineered heart will likely rely on progress in engineering the various components: blood vessels, heart valves, and cardiac muscle. Advances in tissue engineered vascular grafts have shown the most progress to date. Research in tissue-engineered vascular grafts has focused on improving scaffold design, including mechanical properties and bioactivity; genetically engineering cells to improve graft performance; and optimizing tissue formation through in vitro mechanical conditioning. Some of these same approaches have been used in developing tissue engineering heart valves and cardiac muscle as well. Continued advances in scaffold technology and a greater understanding of vascular cell biology along with collaboration among engineers, scientists, and physicians will lead to further progress in the field of cardiovascular tissue engineering and ultimately the development of a tissue-engineered heart. (+info)

Tissue engineering in plastic reconstructive surgery. (5/58)

Tissue engineering (TE) is a new interdisciplinary field of applied research combining engineering and biosciences together with clinical application, mainly in surgical specialities, to develop living substitutes for tissues and organs. Tissue engineering approaches can be categorized into substitutive approaches, where the aim is the ex vivo construction of a living tissue or organ similar to a transplant, vs. histioconductive or histioinductive concepts in vivo. The main successful approaches in developing tissue substitutes to date have been progresses in the understanding of cell-cell interactions, the selection of appropriate matrices (cell-matrix interaction) and chemical signalling (cytokines, growth factors) for stimulation of cell proliferation and migration within a tissue-engineered construct. So far virtually all mammalian cells can be cultured under specific culture conditions and in tissue specific matrices. Future progress in cell biology may permit the use of pluripotent stem cells for TE. The blueprint for tissue differentiation is the genome: for this it is reasonable to combine tissue engineering with gene therapy. The key to the progress of tissue engineering is an understanding between basic scientists, biochemical engineers, clinicians, and industry. (+info)

Engineering of vascular ingrowth matrices: are protein domains an alternative to peptides? (6/58)

Anastomotic intimal hyperplasia and surface thrombogenicity are the main reasons for the high failure rate of prosthetic small-diameter vascular grafts. While anastomotic intimal hyperplasia is a multifactorial event, ongoing surface thrombogenicity is primarily caused by the lack of an endothelium, even after years of clinical implantation. After decades of poorly performing synthetic artery-grafts, tissue engineering has emerged as a promising approach to generate biologically functional bio-synthetic hybrid grafts mimicking native arteries regarding the presence of an endothelial lining on the blood surface. "In vitro endothelialization" represented the first generation of such tissue-engineered vascular grafts, utilising cell culture techniques for the creation of a confluent autologous endothelium on ePTFE grafts. The clinical long-term results with this method in almost 200 patients are highly encouraging, showing patencies equal to vein grafts. Since "in vitro endothelialization" requires cell culture facilities, it will always be confined to large centres. Therefore, research of the 1990s turned to the development of spontaneously endothelializing implants, to make tissue-engineered grafts amenable to the entire vascular-surgical community. Apart from scaffold designs allowing transmural ingrowth, biological signalling through a facilitating ingrowth matrix holds a key to spontaneous endothelialization. In biological signalling, the increasingly deeper understanding of bio-active molecules and the discovery of domains and peptide sequences during the 1980s created the expectation in the 1990s that peptide signalling may be all that is needed. This present review highlights the possible problems associated with such a reductionist approach. Using the fibronectin molecule, we demonstrated that domains may be more suitable modules in tissue engineering than peptide sequences. (+info)

Peripheral nerve injury: a review and approach to tissue engineered constructs. (7/58)

Eleven thousand Americans each year are affected by paralysis, a devastating injury that possesses associated annual costs of $7 billion (American Paralysis Association, 1997). Currently, there is no effective treatment for damage to the central nervous system (CNS), and acute spinal cord injury has been extraordinarily resistant to treatment. Compared to spinal cord injury, damage to peripheral nerves is considerably more common. In 1995, there were in excess of 50,000 peripheral nerve repair procedures performed. (National Center for Health Statistics based on Classification of Diseases, 9th Revision, Clinical Modification for the following categories: ICD-9 CM Code: 04.3, 04.5, 04.6, 04.7). These data, however, probably underestimate the number of nerve injuries appreciated, as not all surgical or traumatic lesions can be repaired. Further, intraabodominal procedures may add to the number of neurologic injuries by damage to the autonomic system through tumor resection. For example, studies assessing the outcome of impotency following radical prostatectomy demonstrated 212 of 503 previously potent men (42%) suffered impotency when partial or complete resection of one or both cavernosal nerve(s). This impotency rate decreased to 24% when the nerves were left intact (Quinlan et al., J. Urol. 1991;145:380-383; J. Urol. 1991;145:998-1002). (+info)

Self-assembly and mineralization of peptide-amphiphile nanofibers. (8/58)

We have used the pH-induced self-assembly of a peptide-amphiphile to make a nanostructured fibrous scaffold reminiscent of extracellular matrix. The design of this peptide-amphiphile allows the nanofibers to be reversibly cross-linked to enhance or decrease their structural integrity. After cross-linking, the fibers are able to direct mineralization of hydroxyapatite to form a composite material in which the crystallographic c axes of hydroxyapatite are aligned with the long axes of the fibers. This alignment is the same as that observed between collagen fibrils and hydroxyapatite crystals in bone. (+info)

Bioartificial organs are typically created with the intent to restore critical biological functions like in the replacement of ... Skin Tissue-engineered skin is a type of bioartificial organ that is often used to treat burns, diabetic foot ulcers, or other ... While some examples of bioartificial organs are still in the research stage of development due to the limitations involved with ... An artificial organ is an engineered device that can be extra corporeal or implanted to support impaired or failing organ ...

https://en.wikipedia.org/wiki/Tissue_engineering

Bhatia's dissertation became the basis for Microfabrication in tissue engineering and bioartificial organs (1999). Bhatia co- ... Bhatia, Sangeeta N. (1999). Microfabrication in Tissue Engineering and Bioartificial Organs. Springer US. ISBN 9781461373865. ... Bhatia, Sangeeta (1999). Microfabrication in tissue engineering and bioartificial organs. Boston: Kluwer Academic Publishers. ... Bhatia, Sangeeta (1999). Microfabrication in tissue engineering and bioartificial organs. Boston: Kluwer Academic Publishers. ...

https://en.wikipedia.org/wiki/Sangeeta_N._Bhatia

Renken A, Hunkeler D (1998). "Microencapsulation: a review of polymers and technologies with a focus on bioartificial organs". ... Hunkeler D (November 2001). "Allo transplants xeno: as bioartificial organs move to the clinic. Introduction". Annals of the ... However, the two major hurdles faced in this technique are the limited availability of donor organs and with the need for ... The potential of using bioartificial pancreas, for treatment of diabetes mellitus, based on encapsulating islet cells within a ...

https://en.wikipedia.org/wiki/Cell_encapsulation

"Present status and perspectives of bioartificial kidneys". J Artif Organs. 9 (3): 130-5. doi:10.1007/s10047-006-0336-1. PMID ... These organs routinely filter about 100 to 140 liters of blood a day to produce 1 to 2 liters of urine, composed of wastes and ... Saito A, Aung T, Sekiguchi K, Sato Y (2006). "Present status and perspective of the development of a bioartificial kidney for ... Kidneys are paired vital organs located behind the abdominal cavity at the bottom of the ribcage corresponding to the levels ...

https://en.wikipedia.org/wiki/Artificial_kidney

... and implanting bioartificial tissues. In 1999 the bladder was the first regenerated organ to be given to seven patients; as of ... Researchers from the University of Edinburgh have succeeded in regenerating a living organ. The regenerated organ closely ... Like other organs, the kidney is also known to regenerate completely in lower vertebrates such as fish. Some of the known fish ... Numerous tissues and organs have been induced to regenerate. Bladders have been 3d printed in the lab since 1999. Skin tissue ...

https://en.wikipedia.org/wiki/Regeneration_in_humans

Safety barrier between a patients blood and a bioartificial liver". The International Journal of Artificial Organs. 19 (11): ... American Society for Artificial Internal Organs Tissue engineering Pless, G. (2007). "Artificial and bioartificial liver ... "Phase I clinical trial with the AMC-bioartificial liver". The International Journal of Artificial Organs. 25 (10): 950-9. doi: ... clinical results of a new membrane-based blood purification system for bioartificial liver support". Artificial Organs. 23 (4 ...

https://en.wikipedia.org/wiki/Liver_support_system

... utilize untransplantable organs as cell sources for cell transplantation or bioartificial organ substitutes, such as ... bioartificial livers, and if the organ proves completely unresuscitatable, utilize them as biocompatible scaffolds for tissue ... In 2008, Uygun was awarded a Career Award by NIDDK at NIH "Computer-Aided Development of a Liver Organ Culture System". In 2009 ... A major research objective of Uygun is to enhance utilization of discarded donor organs in order to either increase the supply ...

https://en.wikipedia.org/wiki/Korkut_Uygun

... artificial organs MeSH E07.858.082.050 - artificial limbs MeSH E07.858.082.212 - bioartificial organs MeSH E07.858.082.374 - ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(E07)

... bioartificial organs for purposes including, but not limited to, customized organ restoration, drug screening, as well as ... Organ printing technology can also be combined with microfluidic technology to develop organ-on-chips. These organs-on-chips ... Developments enabling an organ recipient's host cells to be used to synthesize organs decreases the risk of organ rejection. ... The current regulation for organ matching is centered on the national registry of organ donors after the National Organ ...

https://en.wikipedia.org/wiki/Organ_printing

Highfield, Roger (January 13, 2008). "First bioartificial heart may signal end of organ shortage". The Telegraph. Retrieved ... The first bioartificial hearts were created in 2008 using cadaveric rat hearts. In 2014, human-sized bioartificial pig hearts ... Often, the only viable treatment for end-stage heart failure is organ transplantation. Currently organ supply is insufficient ... A bioartificial heart is an engineered heart that contains the extracellular structure of a decellularized heart and cellular ...

https://en.wikipedia.org/wiki/Bioartificial_heart

Weinberg E, Kaazempur-Mofrad M, Borenstein J (June 2008). "Concept and computational design for a bioartificial nephron-on-a- ... Organ-on-Chip in development hDMT human organ and disease model technologies: pre-competitive non-profit, organ-on-chip ... mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject ... Most organ-on-a-chip models today only culture one cell type, so even though they may be valid models for studying whole organ ...

https://en.wikipedia.org/wiki/Organ-on-a-chip

HepaLife is developing a bioartificial liver device intended for the treatment of liver failure using stem cells. The ... An artificial organ is a human made organ device or tissue that is implanted or integrated into a human - interfacing with ... RFID tags). Organ chips are devices containing hollow microvessels filled with cells simulating tissue and/or organs as a ... Artificial Organs. ISSN 1525-1594. American Society for Artificial Internal Organs (ASAIO) "Elon Musk wants to hook your brain ...

https://en.wikipedia.org/wiki/Artificial_organ

He now works at Ott Lab which focuses on the creation of bioartificial hearts, lungs, tracheas and kidneys. In 2016, another ... Parts of an organ or a whole organ can be cultured in vitro. The main objective is to maintain the architecture of the tissue ... Embryonic organs generally grow well on agar, but adult organ culture will not survive on this medium. The culture of adult ... Cultured organs can be an alternative for organs from other (living or deceased) people. This is useful as the availability of ...

https://en.wikipedia.org/wiki/Organ_culture

Bioartificial organs, which use both synthetic and biological component, are also a focus area in research, such as with ... One of the goals of tissue engineering is to create artificial organs (via biological material) for patients that need organ ... "Doctors grow organs from patients' own cells". CNN. April 3, 2006.. *^ a b Trial begins for first artificial liver device using ... Beyond modeling organs and the human body, emerging engineering techniques are also currently used in the research and ...

https://en.m.wikipedia.org/wiki/Biomedical_Engineering

... ranging from end organ failure to cosmetic surgery. One of the greatest limitations to organ transplantation derives from organ ... Ott, H.C (2008). "Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart". Nature Medicine ... which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical ... Complete organ reconstruction is still in the early levels of development. Researchers are able to take the tissue from a donor ...

https://en.wikipedia.org/wiki/Decellularization

She was the Director, Regenerative Medicine Research and Director, Center for Cell and Organ Biotechnology at the Texas Heart ... February 2008). "Perfusion- decellularized: Using Nature's Platform to Engineer Bioartificial Heart". Nat Med. 14 (2): 213-21. ... research which has uncovered differences in the underlying framework of male and female hearts and other vital organs. Maggie ...

https://en.wikipedia.org/wiki/Doris_Taylor

The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ ... Artificial liver support like liver dialysis or bioartificial liver support concepts are currently under preclinical and ... The risk of ischemic cholangiopathy increases with longer durations of cold ischemia time, which is the time that the organ ... The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient ...

https://en.wikipedia.org/wiki/Liver_transplantation

Being a thoracic surgeon, he focused on the generation of bioartificial airway tissues for tracheo-bronchial replacement. His ... Young Investigator Award of the World Heart Federation 2003 Young Researcher Award of the European Society of Artificial Organs ... Tissue remodelling in a bioartificial fibromuscular patch following transplantation in a human. Transplantation. 2005; 80: 284- ... transplanted patients Walles and his coworkers demonstrated a post-transplant tissue-maturation process of the bioartificial ...

https://en.wikipedia.org/wiki/Thorsten_Walles

American Society for Artificial Internal Organs. *Artificial extracorporeal liver support. *Bioartificial liver device ... Like a bioartificial liver device, it is a form of artificial extracorporeal liver support.[1][2] ... "Clinical application of bioartificial liver support systems". Ann. Surg. 240 (2): 216-30. doi:10.1097/01.sla.0000132986.75257. ...

https://en.m.wikipedia.org/wiki/Liver_dialysis

Washed off cells reach other organs or die, which can be an issue at the time of prepare ICH module 8. Other alternative ... using natures platform to engineer a bioartificial heart". Nat. Med. 14 (2): 213-221. doi:10.1038/nm1684. PMID 18193059. ... cell signaling agents to induce the regeneration of an organ or damaged tissue. In an ideal scenario, regenerated tissue would ... genetic and biomedical engineering for regeneration and cell expansion targets to restructure and/or repair human organs. ...

https://en.wikipedia.org/wiki/Cardiomyoplasty

The NT-3 protein is found within the thymus, spleen, intestinal epithelium but its role in the function of each organ is still ... Currently, neurotrophic factors are being intensely studied for use in bioartificial nerve conduits because they are necessary ...

https://en.wikipedia.org/wiki/Neurotrophic_factors

In addition to scaffold material and physical cues, biological cues can also be incorporated into a bioartificial nerve conduit ... Artificial Organs. 27 (12): 1079-1088. doi:10.1111/j.1525-1594.2003.07208.x. PMID 14678421.CS1 maint: multiple names: authors ... Inserting neurons into a bioartificial nerve conduit seems like the most obvious method for replacing damaged nerves; however, ... Currently, neurotrophic factors are being intensely studied for use in bioartificial nerve conduits because they are necessary ...

https://en.wikipedia.org/wiki/Nerve_guidance_conduit

The Lancet Editors (2016). "Expression of concern-Tracheobronchial transplantation with a stem-cell-seeded bioartificial ... 9 In 2016 she underwent multiple organ transplants in the U.S., and her trachea was replaced with one from a cadaver.[25]:9 ... Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: A proof-of-concept study". The Lancet. ... He obtained degree certificates-a masters in organ and tissue transplantation dated 1994 and a doctorate in the same dated 1997 ...

https://en.wikipedia.org/wiki/Paolo_Macchiarini

The organs known as the accessory digestive organs are the liver, gall bladder and pancreas. Other components include the mouth ... The stomach is a major organ of the gastrointestinal tract and digestive system. It is a consistently J-shaped organ joined to ... A major digestive organ is the stomach. Within its mucosa are millions of embedded gastric glands. Their secretions are vital ... The spleen is the largest lymphoid organ in the body but has other functions.[23] It breaks down both red and white blood cells ...

https://en.wikipedia.org/wiki/Digestive_system

Brouns F, Beckers E (April 1993). "Is the gut an athletic organ? Digestion, absorption and exercise". Sports Med. 15 (4): 242- ...

https://en.wikipedia.org/wiki/Fecal_occult_blood

It is hoped this technique could ultimately help damaged organs and nerves to repair themselves and help transplanted organs to ... Jank, Bernhard J. (2015). "Engineered composite tissue as a bioartificial limb graft". Biomaterials. 61: 246-256. doi:10.1016/j ...

https://en.wikipedia.org/wiki/2015_in_science

By body part: When surgery is performed on one organ system or structure, it may be classed by the organ, organ system or ... Resection is the removal of all of an internal organ or body part, or a key part (lung lobe; liver quadrant) of such an organ ... excision - cutting out an organ, tumor,[9] or other tissue.. *resection - partial removal of an organ or other bodily structure ... reconnection of organs, tissues, etc., particularly if severed. Resection of organs such as intestines involves reconnection. ...

https://en.wikipedia.org/wiki/Surgery

Depending on the organs to be examined, barium radiographs can be classified into barium swallow, barium meal, barium follow- ... With fluoroscopy, it is also possible to visualize the functional movement of examined organs such as swallowing, peristalsis, ...

https://en.wikipedia.org/wiki/Barium_meal

in females, for the limited gynecological palpations of internal organs when you are unable to access the vaginal vault or it ... organ damage, anal bruising, and foreign objects in the rectal cavity; ...

https://en.wikipedia.org/wiki/Rectal_examination

https://en.wikipedia.org/wiki/Resection_

... as organ injury. Indeed, the TAPP approach needs to go through the abdomen. All that said, many surgeons are moving to ...

https://en.wikipedia.org/wiki/Inguinal_hernia_surgery

The chair of (bio) artificial organs addresses several of these challenges by developing an innovative research program, which ... Bioartificial: combining biomaterials and biological cells to fully replace failing patient organs. Typical examples here are ... This chair has the ambition, to take-on the challenge of helping the patients by developing (bio) artificial organs. These ... The complexity increases from artificial to bioartificial organs, and the engineering and regulatory demands increase further ...

https://www.utwente.nl/en/tnw/bst/research/section_stamatialis/

Stephen D. Senturia Cambridge MA Microfabrication in Tissue Engineering and Bioartificial Organs Foreword One of the emerging ... applications of microsystems technology in biology and medicine is in the field of tissue engineering and artificial organs. In ...

https://link.springer.com/book/10.1007/978-1-4615-5235-2

The conduit may be loaded with anti-inflammatory agents and stem cells when complete and this combination bio-artificial organ ... Final Report Summary - NEUROGRAFT (Development of Functionalised Cell Seeded Bioartificial Organ for Transplantation in Nerve ... Development of Functionalised Cell Seeded Bioartificial Organ for Transplantation in Nerve Repair. ...

https://cordis.europa.eu/project/id/304936/reporting

... proposed programme is to conduct a multi-disciplinary research activity in order to evolve bioartificial tissues and organs, ... Bioartificial organs and tissues: a euopean patnership in cellular engineering for improved health and industrial ... Bioartificial organs and tissues: a euopean patnership in cellular engineering for improved health and industrial ... Bioartificial organs and tissues: a euopean patnership in cellular engineering for improved health and industrial ...

https://cordis.europa.eu/project/rcn/30890_pl.html

Its the first tissue-engineered, bio-artificial trachea transplant in a child. Hannahs own stem cells from her own bone ... This area of medicine is expected now to change the way we "replace" damaged or ruined organs and body parts. ... "This view into the future portends the end to organ donation, with its risky anti-rejection drugs and their inherent ... Yet, for all that, concerning the small number of children born with organs that need replacing (what a strange statement), ...

https://www.fortmcmurraytoday.com/2013/05/02/the-miracle-of-the-bio-artificial-organ-transplant/wcm/33500ad6-4152-4237-0929-f88f167e8992/amp/

... this high quality global Bioartificial Organ Manufacturing Market research report is a definitive solution. The data and ... Global Bioartificial Organ Manufacturing Market Scope and Market Size. Bioartificial organ manufacturing market is segmented on ... Market Analysis and Insights of Global Bioartificial Organ Manufacturing Market. Bioartificial organ manufacturing technologies ... global-bioartificial-organ-manufacturing-market. Bioartificial Organ Manufacturing Market analysis report is a comprehensive ...

https://www.pharmiweb.com/press-release/2020-11-06/bioartificial-organ-manufacturing-market-covid-19-impact-analysis-2020-by-top-companies-drivers

A bioartificial kidney could save kidney patients from being stuck on a dialysis machine for life - or dying while waiting for ... LISTENER: How could we improve upon the human organs we already have? Is there a way to make a kidney more efficient by making ... MOSS: What about a bioartificial kidney? I am sure people will come out of the woodwork to think this is a fantastic idea, ... FAKE: But is its promise as a life-changing device enough to bring it to market? Would access to a bioartificial kidney be ...

https://shouldthisexist.com/the-promise-of-bioartificial-organs/

Implantations of living cells, tissue, drugs, medicines and/or enzymes, contained in the bioartificial implants may be made to ... particularly bioartificial pancreases. In particular, the implants may be thin sheets which enclose cells, may be completely ... Bioartificial implants and methods for their manufacture and use are described, ... Artif Organs, 1994. 18(3): p. 193-7.. SUMMARY OF THE INVENTION. The present invention concerns a bioartificial implant and ...

http://www.google.com/patents/US5855613?dq=inventor:%22Arthur+R.+Hair%22&ei=VAy0Tsa4NYTl0QGQiqWiBA

Bioartificial tissues and organs: are we ready to translate? [Lancet. 2011]. *Stem cells in a tissue-engineered human airway. [ ... The bioartificial nanocomposite has patent anastomoses, lined with a vascularised neomucosa, and was partly covered by nearly ... Tailor-made bioartificial scaffolds can be used to replace complex airway defects. The bioreactor reseeding process and ... Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study.. Jungebluth P1 ...

https://www.ncbi.nlm.nih.gov/pubmed/22119609

Bioartificial organ manufacturing market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge ... Home/Business/Global Bioartificial Organ Manufacturing Market to grow at a CAGR of 8.20% 2020-2027. Global Bioartificial Organ ... global-bioartificial-organ-manufacturing-market. The countries covered in the bioartificial organ manufacturing market report ... Bioartificial organ manufacturing technologies are a set of techniques facilitating the development of human organs, based on ...

https://www.mccourier.com/global-bioartificial-organ-manufacturing-marketto-grow-at-a-cagr-of-8-20-2020-2027/

Vascular bioartificial organ. US5593852 *. 1 Sep 1994. 14 Jan 1997. Heller; Adam. Subcutaneous glucose electrode. ...

http://www.google.ca/patents/US20090203979

The main objective of these technologies is to produce high-throughput and/or customized organ substitutes (or bioartificial ... the distinguished potential to eventually manufacture implantable bioartificial organs for purposes such as customized organ ... This article is an overview of the intrinsic/extrinsic properties of the gelatin-based hydrogels in organ 3D bioprinting areas ... Multi-nozzle extrusion-based organ 3D bioprinting technologies have ...

http://www.mdpi.com/2073-4360/9/9/401

Bioartificial kidney alters cytokine response and survival time in acute uremic pigs with multiple organ dysfunction syndrome ... Objective To study the effects of bioartificial kidney(BAK)treatment on cytokines interleukin-10(IL-10)and tumor necrosis ... Bioartificial kidney alters cytokine response and survival time in acute uremic pigs with ... factor-α(TNF-α),biochemistry indexes,and survival time in acute uremic pigs with multiple organ dysfunction syndrome(MODS). ...

https://search.bvsalud.org/gim/resource/en/wpr-392854

ASAIO Journal is the primary source for updates in artificial organ research, development, and testing. In the forefront of the ... THE POSSIBLE MECHANISM OF REDUCED ANTIGENICITY OF THE TRACHEAL BIOARTIFICIAL ORGAN TREATED BY CRYOPRESERVATION. Liu, Yu; Zheng ... NUMERICAL MODELING TO ASSESS OXYGEN AVAILABILITY IN THE AMC BIOARTIFICIAL LIVER. Mareels, Guy; Poyck, Paul P.; Eloot, Sunny; ... CHARACTERIZATION OF A NOVEL PORCINE LIVER SLICE-FILLED BIOARTIFICIAL LIVER (BAL) FOR TREATMENT OF LIVER FAILURE PATIENTS. ...

https://journals.lww.com/asaiojournal/toc/2006/03000

Ultrafiltration membrane, device, bioartificial organ, and related methods. US9433573. Jun 1, 2015. Sep 6, 2016. Delpor, Inc.. ... Ultrafiltration membrane, device, bioartificial organ, and methods. US20050072689 *. Mar 6, 2003. Apr 7, 2005. Reimar Spohr. ... Ultrafiltration membrane,device, bioartificial organ, and methods. US20060282115 *. Jun 9, 2005. Dec 14, 2006. Abrams Robert M ... Ultrafiltration membrane device, bioartificial organ, and related methods. US20020119589 *. Jan 24, 2002. Aug 29, 2002. Frank ...

http://www.google.com/patents/US5985164?dq=Xerox+%2B+%22centroid

ASAIO Journal is the primary source for updates in artificial organ research, development, and testing. In the forefront of the ... HYBRID ORGANS/TISSUE ENGINEERING/CLONNING: BIOARTIFICIAL PHAGOCYTOSIS ASSIST - A NEW TOOL IN CRITICAL CARE MEDICINE. ... HYBRID ORGANS/TISSUE ENGINEERING/CLONNING: TRANSPORT OF TOXINS THROUGH A NEW IMMUNOLOGICAL BARRIER BETWEEN A BIOARTIFICIAL ... HYBRID ORGANS/TISSUE ENGINEERING/CLONNING: ORGANOTYPICAL IN VITRO MODEL FOR 3-D CULTURE OF HEPATOCYTES AND HEPATIC NON ...

https://journals.lww.com/asaiojournal/toc/1998/03000

Bioartificial tissues and organs: are we ready to translate?. Ott HC, Mathisen DJ.. Lancet. 2011 Dec 10;378(9808):1977-8. Epub ... Recellularization of organs: what is the future for solid organ transplantation?. Moser PT, Ott HC. Curr Opin Organ Transplant. ... On the road to bioartificial organs.. Ren X, Ott HC.. Pflugers Arch. 2014 Oct;466(10):1847-57. doi: 10.1007/s00424-014-1504-4. ... Decellularized scaffolds as a platform for bioengineered organs.. Tapias LF, Ott HC.. Curr Opin Organ Transplant. 2014 Apr;19(2 ...

http://www.massgeneral.org/research/researchlab.aspx?id=1772

Int J Bioartificial Organs 33:512-525Google Scholar. *. Weber C, Pohl S, Poertner R, Pino-Grace P, Wallrapp C, Geigle P, ...

https://link.springer.com/article/10.1007%2Fs10616-011-9359-4

... bioartificial) organs; biomaterials; biomechanics and rehabilitation, including orthopedics and sports medicine; medical ...

https://www.journals.elsevier.com/biocybernetics-and-biomedical-engineering

Stem Cell-Based Bioartificial Tissues and Organs. Surgeon Paolo Macchiarini has made his name by successfully transplanting ...

http://www.innovationtoronto.com/tag/acute-liver-failure/

But what of the hundreds of thousands of patients with chronically diseased organs? Bioartificial-organ technology could ... Bioartificial organs most compelling use may be for kidney failure patients. While a strictly artificial device such as a ... While bioartificial organs offer benefits that purely mechanical devices cant match, they still have some severe limitations. ... As Paganini puts it, "The concept of a bioartificial organ is in and of itself exciting." But whats even more exciting to ...

https://www.technologyreview.com/s/402031/saving-lives-with-living-machines/

New Phase of Growth for Xenogeneic-Based Bioartificial Organs. Next Article in Special Issue. Extracts of Magnolia Species- ...

http://www.mdpi.com/1422-0067/17/9/1586

So to the future of bioartificial organs. A computer doesnt look much like a brain, a slide-rule, or a typewriter. The ... Regenerative medicine moves forward, organ by organ: "The trachea and other respiratory tubes, like most tubes in the body, ... bioartificial organs; massive computational capacities; a complete control over evolved biological cells; a working ... At a comparable stage in the advance of biotechnology, today we see that bioartificial implants - cells combined with ...

https://www.fightaging.org/archives/2008/05/longevity-meme-newsletter-may-12-2008/

Bhatias dissertation became the basis for Microfabrication in tissue engineering and bioartificial organs (1999). Bhatia co- ... Bhatia, Sangeeta N. (1999). Microfabrication in Tissue Engineering and Bioartificial Organs. Springer US. ISBN 9781461373865. ... Bhatia, Sangeeta (1999). Microfabrication in tissue engineering and bioartificial organs. Boston: Kluwer Academic Publishers. ... Bhatia, Sangeeta (1999). Microfabrication in tissue engineering and bioartificial organs. Boston: Kluwer Academic Publishers. ...

https://en.wikipedia.org/wiki/Sangeeta_N._Bhatia

https://en.wikipedia.org/wiki/Tissue_engineering

Generation of Bioartificial Salivary Gland Using Whole-Organ Decellularized Bioscaffold.. Gao Z, Wu T, Xu J, Liu G, Xie Y, ... Cells Tissues Organs. 2014;200(3-4):171-80. doi: 10.1159/000371873. Epub 2015 Mar 25. ... Cells Tissues Organs. 2016;201(1):65-76. doi: 10.1159/000440952. Epub 2015 Nov 17. ...

https://www.ncbi.nlm.nih.gov/pubmed/?cmd=Search&term=Guolin%20Liu

Investigating whole-organ tissue engineering of bioartificial organs for transplantation. *Exploring new preservation ... Uygun BE, Yarmush ML, Uygun K. Application of whole-organ tissue engineering in hepatology. Nat Rev Gastroenterol Hepatol. 2012 ... Developing new studies that challenge the current dogma regarding the underlying mechanisms of multi-system organ failure in ... The center focuses on artificial organ development, biopreservation, metabolic engineering, stem cell bioengineering, ...

https://www.massgeneral.org/surgery/research/researchlab.aspx?id=1615&display=projects

Kidney bioengineering, Organ development, Cell therapy, Bioartificial , Review. Send correspondence to: Steven H. Kim, ... Current strategies and challenges in engineering a bioartificial kidney Steven Kim 1 2 , William H. Fissell 3 , H. David Humes ... Renal replacement therapy was an early pioneer in both extra-corporeal organ replacement and whole organ transplantation. Today ... Bioartificial renal epithelial cell system (BRECS). 7.3. Implantable renal assist device (iRAD). 8. Discussion. 9. Conclusion. ...

http://www.bioscience.org/2015/v7e/af/729/3.htm

... bioartificial organs and regeneration of injured tissue in the body. In order to successfully create bioartificial organs from ... Bioartificial windpipe : The first procedure of regenerative medicine of an implantation of a "bioartificial" organ. ... Bioartificial organs In 2013, a group from the University of Tokyo developed cell laden fibers up to a meter in length and on ... An artificial organ is a man-made device that is implanted or integrated into a human to replace a natural organ, for the ...

http://www.netlibrary.net/articles/eng/Tissue_engineering

Tissue engineering aims to create bio-artificial organs in the laboratory. Tissue engineering is beneficial in providing ...

https://www.news-medical.net/health/Micro-CT-Applications-in-Dentistry.aspx

Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study. (nih.gov)
We report the clinical transplantation of the tracheobronchial airway with a stem-cell-seeded bioartificial nanocomposite. (nih.gov)
The Ott Laboratory is working to develop new tissue engineering strategies for regenerating whole organs and organ grafts as an alternative to donor transplantation. (massgeneral.org)
Currently, organ transplantation is the only potentially curative therapy available. (massgeneral.org)
The Ott Laboratory is investigating tissue engineered organs as an alternative to donor transplantation. (massgeneral.org)
The human heart project in the Ott Laboratory aims to engineer a bioartificial heart for clinical application and transplantation. (massgeneral.org)
Renal replacement therapy was an early pioneer in both extra-corporeal organ replacement and whole organ transplantation. (bioscience.org)
The Education Committee (EC) of the European Society for Organ Transplantation (ESOT) is a formally established committee of ESOT aiming to advance transplant education in Europe for all disciplines related to the field of transplantation. (esot.org)
The Young Professionals in Transplantation (YPT) is the Network for Junior Transplant professionals of ESOT, representing all young transplant clinicians and scientists who are beginning a career in transplantation and organ donation. (esot.org)
The mission of ECTORS is to provide a forum for discussing and stimulating novel developments in the fields of cellular therapies in organ transplantation, organ regeneration and generation of new organs from stem cells and biomaterials. (esot.org)
EDTCO aims to support health care professionals to provide clinically effective programmes on organ and tissue donation, procurement and transplantation. (esot.org)
In the majority of the cases the only so far curable therapeutic option is an allogenic organ transplantation. (confex.com)
However, conventional transplantation is associated with a shortage of donor organs and a lifetime of immunosuppressant, which is a non-ideal solution. (confex.com)
Thus, the implementation of tissue bioengineering to organ regeneration has emerged as an alternative to traditional organ transplantation. (frontiersin.org)
The recellularization of these scaffolds with different cell sources, such as stem cells or adult differentiated cells, can provide an organ with functionality and no immune response after in vivo transplantation on the host. (frontiersin.org)
2 Department of Cardiac-, Thoracic-, Transplantation and Vascular Surgery, Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Carl-Neuberg-Str. (osapublishing.org)
Cardiac tissue engineering is a promising strategy for regenerative therapies to overcome the shortage of donor organs for transplantation. (osapublishing.org)
Due to the shortage of liver donors for orthotropic liver transplantation, bioartificial liver systems are currently considered as an alternative therapy for liver failure in clinical trials ( 1 ). (medsci.org)
A bioartificial kidney could replace the need for dialysis or transplantation in the millions of patients with kidney failure. (eurekalert.org)
This report analyzes the worldwide markets for Organ and Tissue Transplantation in number of organs transplanted. (marketpublishers.com)
The Global and regional markets (except the US) for Organ and Tissue Transplantation in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, Lungs, and Corneal Transplantation). (marketpublishers.com)
We have active projects in our lab using pluripotent stem cells to also derive lung endothelium, fibroblasts, and smooth muscle cells as part of our long-term goal of generating the full cellular diversity and structural complexity of the entire lung organ for future transplantation studies and disease models. (bu.edu)
This research clearly will lead to advances in organ transplantation and contribute to breakthroughs in health care. (fairfield.edu)
In her announcement, Provost Christine Siegel, PhD, described Dr. Sundarram's research proposal, "Microwave Foamed Tissue Scaffolds for Bio-Artificial Organs," as "exceedingly well-crafted" and noted, "This research clearly will lead to advances in organ transplantation and contribute to breakthroughs in health care… a field critical to society. (fairfield.edu)
Dr. Reich serves in numerous national leadership roles, including as member of the Board of Directors and Region 2 Councilor for the United Network for Organ Sharing (UNOS), chair of the Quality and Pay Reform MACRA Task Force and past chair of the Standards Committee and of the Legislative Committee of the American Society of Transplant Surgeons, and Member of the Editorial Board of Liver Transplantation. (hahnemannhospital.com)
Dr. Soto-Gutierrez's research is focused on the development of new technologies for organ replacement using regenerative medicine approaches (bioengineering, cell transplantation and organ engineering) to generating entire replacement organs, Dr. Soto-Gutierrez's laboratory use the structural connective tissue of discarded livers as a scaffold for growing new liver tissue for transplantation and primary liver isolated cells. (upmc.edu)
While portions of the studies are carried out in organ culture systems, several ongoing studies are performed in special animal models of liver regeneration to understand hepatic tissue assembling and regeneration using auxiliary partial orthotopic liver transplantation (APOLT). (upmc.edu)
In few cases, artificial organs are capable of eliminating the need for organ transplantation altogether. (sbwire.com)
Many patients die, however, before a suitable graft is available, and for those who progress to multi-organ failure, transplantation is not an option. (biomedcentral.com)
Scarcity of organs & tissues for transplantation also has a positive impact. (abnewswire.com)
Although these initial clinical trials have made use of transplantation of stem cells via a vascular route, we are now establishing grafting strategies for transplantation of stem cells into and onto internal organs. (unc.edu)

Typical examples here are: (i) bioartificial kidney devices, combining biomaterials and kidney epithelial cells for improved blood detoxification (ii) bioartificial pancreas devices, combining encapsulation of pancreatic cells for treatment of diabetes (iii) development of a bioartificial lungs for studying lung regeneration. (utwente.nl)
Use of the medaka fish as a model to study human diseases such as cancer and the functional regeneration of tissues and organs. (bath.ac.uk)
A "failed experiment" became a life-saving discovery by MIT Professor Ioannis V. Yannas and his colleague Dr. John Burke when their search for a better way to treat severe burn victims led to the discovery of organ regeneration. (mit.edu)
The principal research interest of Dr Yannas is the process of induced organ regeneration used to replace organs that are either severely injured or are terminally diseased. (mit.edu)
Hesitant steps from the artificial skin to organ regeneration. (mit.edu)
This work resulted in the first patent on induced organ regeneration. (mit.edu)
Regeneration in humans is the regrowth of lost tissues or organs in response to injury. (wikipedia.org)
Some tissues such as skin and large organs including the liver regrow quite readily, while others have been thought to have little or no capacity for regeneration. (wikipedia.org)
However ongoing research, particularly in the heart and lungs, suggests that there is hope for a variety of tissues and organs to eventually become regeneration-capable. (wikipedia.org)
Advances in research have enabled the induced regeneration of many more tissues and organs than previously thought possible. (wikipedia.org)
In 2009, the regeneration of hollow organs and tissues with a long diffusion distance, was a little more challenging. (wikipedia.org)
This review focuses mainly on tissue and organ regeneration using SC and in particular MSC. (hindawi.com)
The early results are encouraging and pave the way for further investigations to understand the interactions between the organ structures and cells and to identify the optimal cell type to achieve complete regeneration of the endothelium and islets," said Orlando. (eurekalert.org)
It specifically emphasizes the regeneration of bone, cartilage, and osteochondral tissues as well as soft tissues such as nerves, heart, and endocrine organs. (panstanford.com)
Extensive research in organ regeneration through engineered tissues would open new opportunities. (abnewswire.com)

This review will examine the state-of-the-art in kidney bioengineering by evaluating the various techniques currently being utilized to create a bioartificial kidney. (bioscience.org)

For reaching towards the success at local, regional as well as international level, this high quality global Bioartificial Organ Manufacturing Market research report is a definitive solution. (pharmiweb.com)

In the coming years, due to the aging of the population and the low availability of donor organs there will be urgent need for bioengineering solutions to assist, mimic or replace failing patient organs. (utwente.nl)
However, its outcomes are limited by shortage of donor organs and the side effects of harsh immunosuppressive treatments designed to prevent the body from rejecting the organ. (massgeneral.org)
The goal is to create various whole organs that are derived from a patient's own cells, and transplanting them into patients, avoiding the need for a donor. (massgeneral.org)
For this reason, organ donor recipients have to take drugs that suppress the immune system. (zdnet.com)
Dr. Macchiarini has used scaffolds to successfully replace windpipes from cadavers in about a dozen patients who don't have the major problem facing other organ donor recipients: the risk of organ rejection. (zdnet.com)
But scaffolds still have some problems of traditional organ transplants: They require donor organs, for which there is a long waiting list, and the patient has to wait for the organ to be stripped of cells. (zdnet.com)
Although both patients died as a consequence of multi-organ failure, the result has provided the first evidence that stem cell therapy can be a promising alternative to restore function in certain damaged organs - without the need for them to be removed and replaced with healthy donor organs. (regenerativemedicine.net)
He has conducted internationally recognized research into safe use of extended criteria donor organs, bioartificial liver support, and healthcare performance improvement. (hahnemannhospital.com)

Artificial: based on new biomaterials and novel designs, to assist or mimic a patient organ. (utwente.nl)
Bioartificial: combining biomaterials and biological cells to fully replace failing patient organs. (utwente.nl)
The main objective of these technologies is to produce high-throughput and/or customized organ substitutes (or bioartificial organs) with heterogeneous cell types or stem cells along with other biomaterials that are able to repair, replace or restore the defect/failure counterparts. (mdpi.com)
He completed a residency in general surgery at the Massachusetts General Hospital and while a surgical resident, received a PhD in Chemical Engineering at the Massachusetts Institute of Technology with a focus on artificial organs and the design of biomaterials for reconstructive surgery. (harvard.edu)
the biorobotics curriculum is focused on the development of humanoid and animaloid robot models, wearable robots, bionic implantable organs, artificial upper and lower limbs, robots and platforms for diagnosis, surgery and rehabilitation, computational biomechanics, micro/nano-robots and biomaterials. (imtlucca.it)
The potential of biomaterials is manifested in diverse areas and every organ in our bodies have benefited from them in one form or another. (frontiersin.org)
These organs are incorporated with different technologies like sensors, biomaterials, and innovative delivery systems. (sbwire.com)

A bioartificial kidney could save kidney patients from being stuck on a dialysis machine for life - or dying while waiting for a rare transplant. (shouldthisexist.com)
There are alternatives to dialysis - organ transplant. (shouldthisexist.com)
Already in human trials, these bioartificial livers could help patients in acute liver failure, whose only chance today is a rare organ transplant. (technologyreview.com)
Even such temporary support could be a boon for medicine, sustaining thousands of patients and enabling them to regain the function of their own organs or survive until transplant organs become available. (technologyreview.com)
There are also plans to transplant the esophagus, an organ that is more complex than a trachea as it has muscles. (regenerativemedicine.net)
The lack of transplant vascularization forecloses the generation and clinical implementation of bioartificial tissues. (fraunhofer.de)
a leader in the research and development of a bioartificial pancreas , a minimally invasive cellular transplant for the treatment of insulin-dependent diabetes mellitus, has obtained exclusive rights for diabetes cell therapy from the University of Texas to United States Patent Number 5,529,914, issued on June 25, 1996. (thefreedictionary.com)
Clinical and laboratory research to reduce organ rejection and improve transplant success. (hahnemannhospital.com)
Italian specialists in biological membranes review recent developments in membranes and investigate how they can be used to improve the quality and efficiency of artificial organs as an aging population increases the demand for organ transplant while it decreases the supply. (thefreedictionary.com)
Each year, there is a severe shortage of kidneys for organ transplant. (ufl.edu)

After all the cells were gone (in three days), what was left of the organs was the scaffold, the basic shape of the organ, composed of a matrix of proteins and other compounds that keep the right cells in the right places. (zdnet.com)
In contrast, organ specific properties can vary from time to time e.g. for the trachea air- and liquid-tight seals, flexibility and strength to prevent the collapse of the scaffolds, and must be considered when choosing the ideal scaffold. (confex.com)
When asked to describe his research "in layman's terms," Dr. Sundarram compared the building block of bio-artificial organs - a three-dimensional porous tissue scaffold - to a regular sponge with hollow channels that provide pathways for water flow and absorption. (fairfield.edu)
Extracellular matrix scaffold technology for bioartificial pancreas engineering: state of the art and future challenges. (thefreedictionary.com)
Organs are made by plac- ing a culture of cells from a patient's organ onto a shaped tissue scaffold. (sciencephoto.com)
Fed by special nutrients the cells multiply using the fibres as a scaffold to form an organ in a few weeks. (sciencephoto.com)
Examining the ability of these cells to proliferate and differentiate in a whole kidney extracellular matrix scaffold would serve as a valuable baseline for future studies in producing a functioning organ. (ufl.edu)
Our work is aimed at the bioartificial fabrication of functional lungs by recellularizing the organ scaffold with stem cells and recreating the in vivo mechanical micro/ nano -environment. (ub.edu)

Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives. (bioportfolio.com)
Design and fabrication of bioreactors for cell-based therapies, cell expansion, in vitro models and bioartificial organs. (bath.ac.uk)
Thus far, immortalized human hepatocytes with indefinite expansion in vitro and allogeneic cells are ideal for bioartificial liver system applications ( 2 - 4 ). (medsci.org)
The metabolic activity of the bioartificial tissue increased continuously over time ill vitro. (fraunhofer.de)
Such in vitro -generated cells may be very useful for the development of bioartificial organs ( 14 ) or cell-based therapies in chronic or acute renal failure. (asnjournals.org)

But, the New York Times reports , scientists are working on creating more complex organs such as kidneys and livers with these techniques. (zdnet.com)
Implanting such a "bioartificial" organ would be a first-of-its-kind procedure for the field of regenerative medicine, which for decades has been promising a future of ready-made replacement organs - livers, kidneys, even hearts - built in the laboratory. (nytimes.com)
The cells are made available to carry out subtle metabolic and endocrine functions that the patient's failing kidneys can no longer perform, thereby staunching a cascading decline in the patient's health and allowing time for the patient's own organs to recover,' Dr. Humes explains. (medgadget.com)
It would be interesting to be able to use patient cells to make bioartificial kidneys. (hubrecht.eu)

Traditional medical treatments for functional deficiencies of biological organs have focused on replacing identified normal secreted products of the deficient organ with natural or synthetic pharmaceutical compositions. (google.com)
On the basis of material, the bioartificial organ manufacturing market is segmented into mechanical, biomechanical and biological. (mccourier.com)
Decellularization of organs with chemical, physical, and/or biological agents generates natural scaffolds, which can serve as basis for tissue reconstruction. (frontiersin.org)
Biomechanics is the study of the structure and function of the mechanical aspects of biological systems, at any level from whole organisms to organs , cells and cell organelles , [3] using the methods of mechanics . (wikipedia.org)
One of the goals of tissue engineering is to create artificial organs (via biological material) for patients that need organ transplants. (wikipedia.org)

Fetal and adult stem cells are undifferentiated cells, which can be found within fetus or in adult tissues or organs. (hindawi.com)
These principals also form the foundation for strategies for cell therapies for dysfunctional tissues or organs. (unc.edu)
Tissue engineering is a set of biomedical, biotechnological and engineering techniques that aim to maintain, regenerate or replace tissues or organs. (scielo.br)

The creation of a transplantable, bioengineered kidney that can permanently replace kidney function could address this severe organ shortage and, at the same time, allow recipients to avoid the side effects of immunosuppressant drugs. (massgeneral.org)
However, the shortage of available organs, as well as the high rate of organ rejection, supports the need for new therapies. (frontiersin.org)

Blood pressure crashes, starving the body of oxygen, and in short order the lungs, liver, and other organs begin to fail. (technologyreview.com)
He now plans to use the technique to recreate more complex tissues, such as the esophagus and diaphragm or organs such as the heart and lungs. (regenerativemedicine.net)
In 2009, we began a now long-standing collaboration with Dr. Harald Ott of Massachusetts General Hospital, resulting in 2010 in the publication of the first successfully transplanted bioartificial lungs in rat recipients . (bu.edu)

It's pretty obvious that with advances in stem cell technology, computer science, engineering and 3D printing, we will one day be able to create bioartificial tissue and implantable organs," said Markus Reiterer, senior principal scientist at Medtronic. (medtronic.com)

To address these problems, researchers have turned to using cell-based therapies for the development of a bioartificial kidney. (bioscience.org)

These results may open the door for the clinical application of various sophisticated bioartificial tissue substitutes and organ replacements. (fraunhofer.de)

So far, only a few such organs have been created and transplanted, and the they aren't complex organs -- just simples one like bladders and a windpipe. (zdnet.com)
For complex organs, such as heart, lung or the liver, cell therapy and pharmaceutical intervention can be an optimum alternative. (confex.com)
But scientists around the world are using similar techniques with the goal of building more complex organs. (nytimes.com)
Tissue engineers caution that the work they are doing is experimental and costly, and that the creation of complex organs is still a long way off. (nytimes.com)

Bhatia studied bioengineering at Brown University where she joined a research group studying artificial organs which convinced her to pursue graduate study the field. (wikipedia.org)

Living membranes' of renal epithelial cells on biofunctionalized membranes (the 'bioartificial kidney' (BAK)) have been shown to improve the removal of protein-bound toxin, representing a great leap forward for dialysis patients. (utwente.nl)
The aim of this proposed programme is to conduct a multi-disciplinary research activity in order to evolve bioartificial tissues and organs, utilising the phenomena and materials from cells. (europa.eu)
Implantations of living cells, tissue, drugs, medicines and/or enzymes, contained in the bioartificial implants may be made to treat and/or prevent disease. (google.com)
The present invention may be used for implantation of living cells, tissue, drugs, medicines and/or enzymes, contained in the bioartificial implants. (google.com)
He proposed the joining of the terms tissue (in reference to the fundamental relationship between cells and organs) and engineering (in reference to the field of modification of said tissues). (wikipedia.org)
Developed after a decade of research by University of Michigan internist David Humes, this hybrid of living cells and artificial structure is at the forefront of a pragmatic effort to find an effective treatment for people whose organs have failed. (technologyreview.com)
And it's only one example of the increasingly popular strategy of using living cells to do the heavy lifting in artificial organs. (technologyreview.com)
Scientists are beginning to come up with a way to help patients who need organ transplants: to create them a new organ using their own cells. (zdnet.com)
Scientists are having preliminary success with a new way to get patients new organs that they may need: bioartificial organs made of plastic and the patient's own cells. (zdnet.com)
A detergent-like liquid connected via tube dripped into the jar and out, slowly stripping the organs of their living cells. (zdnet.com)
Co-culturing with the HSC-Li cells improved the liver-specific functions of hepatocytes, which may be valuable and applicable for bioartificial liver systems. (medsci.org)
The (bio)artificial organs chair of Professor Dimitrios Stamatialis focuses on the development of novel immune-protective membrane-based cell encapsulation devices, containing insulin producing cells for regulation of blood glucose in T1D, without the need for injections and immunosuppressive drugs. (utwente.nl)
First, the discarded organs were washed in a mild detergent to remove all cells, a process that is known as decellularization. (eurekalert.org)
The idea is based on evidence that the decellularized organs contain proteins and other substances that play a vital role in the survival, welfare and function of the organ's cells. (eurekalert.org)
In theory, these organ structures could be re-populated with a patient's own cells. (eurekalert.org)
In both cases, the organs structures were cell-friendly and allowed the cells to attach, function and maintain their original cell type. (eurekalert.org)
Now, however, researchers like Dr. Macchiarini are building organs with a different approach, using the body's cells and letting the body itself do most of the work. (nytimes.com)
They want to make organs with the cells, blood vessels and nerves to become a living, functioning part of the body. (nytimes.com)
These studies provide a proof of concept for using oxygen-generating materials to solve one of the major obstacles to engineering a bioartificial pancreas - making sure the cells have enough oxygen to function until the structure integrates with the body," said lead scientist Emmanuel C. (thefreedictionary.com)
As a substitute to these options, scientists are working to build a bioartificial pancreas by encapsulating insulin-producing cells within tiny biocompatible beads. (thefreedictionary.com)
The "renal assist device" (RAD) is a bioartificial kidney - a device lined with human renal tubular cells grown from donated organs. (medgadget.com)
these acellular scaffolds retain the native organ ultrastructure and can be seeded with autologous cells towards the goal of regenerating functional tissues. (nih.gov)
One of the models suitable for this application is an organoid - a miniature organ, grown from adult stem cells. (hubrecht.eu)
The culture of kidney organoids can be made compatible with the development of the bioartificial kidney - a filter containing living kidney cells, that might someday be able to replace conventional dialysis. (hubrecht.eu)
We also have resident stem cells in every organ of the body. (parentsguidecordblood.org)
Through her pioneering work, we now have the capability to deplete animal and human hearts of all of their cellular structure and regenerate the "decellularized" scaffolds into healthy organs by the infusion of stem cells. (parentsguidecordblood.org)
Many believe that these "bioartificial" organs are the early steps toward our ability to grow new organs for people using their own adult stem cells. (parentsguidecordblood.org)
Artificial organs are another possible lifesaver, but like gene-editing pig cells to create transplantable organs, the technology is not complete. (thefreedictionary.com)
February 9, 2018 -- Medical researchers envision a day when a sick person with a diseased heart or other organ can get a new one, designed on a computer, made specifically for their personal anatomy and created from stem cells, or perhaps even their own cells, on a 3D printer. (medtronic.com)
Ideally, the resulting extracellular matrices would retain the organ-specific architecture and chemical composition to guide implanted cells into functional structures and eventually working organs. (ufl.edu)
If recognition of these phenomena is utilized in strategies for handling cells, then these cells (of any tissue and from any species) can be maintained as stem cells or as one of the intermediates in the maturational cell lineages or as fully mature cells ex vivo in monolayer cultures, in organoid cultures (floating aggregates of the cells), or as bioartificial organs in perfusion bioreactors. (unc.edu)
Addition of Bmp7 further enhanced the ability of these cells to contribute to developing tubules in a kidney organ culture system. (asnjournals.org)

Chicago, IL (November 19, 2016) -- Investigators are getting closer to creating a functional bioartificial kidney, with advances being presented at ASN Kidney Week 2016 November 15¬-20 at McCormick Place in Chicago, IL. (eurekalert.org)
Engineering of bioartificial organs using either natural or synthetic scaffolds is an exciting new potential option for generation of functional pulmonary tissue for human clinical application. (nih.gov)

While a strictly artificial device such as a dialysis machine can cleanse the blood, it can't replace or mimic the subtler metabolic functions of a large, complex organ like the kidney. (technologyreview.com)
This study shows the successful development of a living membrane consisting of a reproducible ciPTEC monolayer on hollow fiber membranes, an important step towards the development of a bioartificial kidney device," said Prof. Stamatialis. (eurekalert.org)
Neocrin is a leader in the research and development of a bioartificial pancreas , a minimally invasive implantable device, to treat insulin-dependent diabetes. (thefreedictionary.com)

The Ott Laboratory developed and first reported a novel technique to isolate the whole organ extracellular matrix (ECM) scaffolds by a process called perfusion decellularization. (massgeneral.org)

Human scaffolds could be better for building new organs than synthetic scaffolds that just try to imitate nature. (zdnet.com)

RM aims to replace and regenerate damaged tissue to restore organ function. (confex.com)
There are some human organs and tissues that regenerate rather than simply scar, as a result of injury. (wikipedia.org)
Therefore, to regenerate hollow organs and tissues with a long diffusion distance, the tissue had to be regenerated inside the lab, via the use of a 3D printer. (wikipedia.org)
Most of human tissues and organs do not regenerate spontaneously, justifying why cell therapy is today a significant tissue and organ repair strategy. (hindawi.com)
It is an interdisciplinary field combining many techniques that aim to maintain, regenerate or replace a tissue or organ. (scielo.br)

This project draws from expertise in stem cell biology, developmental biology, physiology, cardiology, and biomedical engineering in pursuit of creating a bioartificial heart as an alternative treatment option for patients in need of heart transplants. (massgeneral.org)
One of the problems of organ transplants is the potential for the body to reject the foreign organ. (zdnet.com)
An ingenious method for making new organs could one day revolutionize medical transplants. (technologyreview.com)

Artificial Vital Organs And Medical Bionics Market Is Expected To Grow Owing To Increased Demand In Medical Sectors Till 2022: Grand View Research, Inc. (abnewswire.com)
The artificial vital organs and medical bionics market was valued USD 23 billion in 2014. (abnewswire.com)
By 2022, revenues of the artificial vital organs and medical bionics market could surpass USD 44 billion. (abnewswire.com)
Products include artificial vital organs, medical bionics, and cardiac bionics. (abnewswire.com)
Artificial vital organs, with 65% of the revenues, dominated the market in 2014. (abnewswire.com)
Regions wise, the artificial vital organs and medical bionics market encompasses North America, Europe, Asia Pacific, and Rest of the World (RoW). (abnewswire.com)

The complexity increases from artificial to bioartificial organs, and the engineering and regulatory demands increase further if these organs would be extracorporeal or implantable. (utwente.nl)
These advantages allow hydrogels to be developed as an extracorporeal bio-artificial organ, space filling material, and delivery vehicle. (medindia.net)
These scaffolds with desired properties will be incorporated into bioreactor chambers integrated with sensors and fluidic networks, resulting in extracorporeal bio-artificial organs," he explained. (fairfield.edu)

This view into the future portends the end to organ donation, with its risky anti-rejection drugs and their inherent complications, and the start of a new age of science and technology with the creation of bioengineered organs and the cure for human disease. (fortmcmurraytoday.com)
Bioartificial organ manufacturing technologies are a set of techniques facilitating the development of human organs, based on bionic principles. (pharmiweb.com)
Three-dimensional (3D) bioprinting is a family of enabling technologies that can be used to manufacture human organs with predefined hierarchical structures, material constituents and physiological functions. (mdpi.com)
We developed techniques to generate a bioartificial human tissue with all innate vascularization. (fraunhofer.de)
But what if the answer is to "recycle" the more than 300 human pancreata from organ donors that aren't currently being used? (eurekalert.org)
MAILPAN (MAcroencapsulation of PANcreatic Islets) is a prototype of bioartificial pancreas usable in the human designed to treat type 1 diabetic patients. (thefreedictionary.com)
Boston, MA -- ( SBWIRE ) -- 02/09/2017 -- Artificial organs are human-made bioartificial devices, which are implanted or integrated into individuals to replace or support natural organs. (sbwire.com)
n.pl the devices used to support life because of the failure or limited capacity of the human organ. (thefreedictionary.com)
Scientist makes materials used in tissue scaffolds to grow artificial human organs outside the body for implantation. (sciencephoto.com)

Sol-gel encapsulation has a variety of applications in biotechnology and medicine: creating biosensors, biocatalysts, and bioartificial organs. (umn.edu)
The graduate program is designed for students interested in a range of topics related to the field of biotechnology including drug and gene delivery, prosthetic devices, cancer therapeutics, vascular grafts, tissue engineering, disease diagnostic assays and bioartificial organs. (brown.edu)

Gelatin-based hydrogels, such as gelatin/fibrinogen, gelatin/hyaluronan and gelatin/alginate/fibrinogen, have unique features in organ 3D bioprinting technologies. (mdpi.com)
This article is an overview of the intrinsic/extrinsic properties of the gelatin-based hydrogels in organ 3D bioprinting areas with advanced technologies, theories and principles. (mdpi.com)
Multi-nozzle extrusion-based organ 3D bioprinting technologies have the distinguished potential to eventually manufacture implantable bioartificial organs for purposes such as customized organ restoration, high-throughput drug screening and metabolic syndrome model establishment. (mdpi.com)

Objective To study the effects of bioartificial kidney (BAK) treatment on cytokines interleukin-10 ( IL-10 )and tumor necrosis factor -α(TNF-α), biochemistry indexes,and survival time in acute uremic pigs with multiple organ dysfunction syndrome ( MODS ). (bvsalud.org)

Adipose tissue is an endocrine and paracrine organ that contributes to both metabolic and vascular homeostasis . (fightaging.org)

But the real revolution will come with the development of permanent, implantable bioartificial organs. (technologyreview.com)
The strategies and methods of this work could be relevant to the development of other bioartificial organs, such as a bioartificial liver or bioartificial pancreas, and organs on chips--such as a kidney on chip, a lung on chip, or a liver on chip. (eurekalert.org)
With this scenario, the future growth of artificial organs development appears to be obvious with tissue engineering and artificial organ development. (thefreedictionary.com)

Bioartificial implants and methods for their manufacture and use are described, particularly bioartificial pancreases. (google.com)
The present invention is directed to the field of bioartificial pancreases, bioartificial implants generally, and methods for their manufacture and use. (google.com)
The present invention also concerns implantations made using these bioartificial implants. (google.com)

Many studies used several techniques that are herein presented, including biopolymers, decellularization and bioreactors, and made significant advances, either seeking a graft or an entire bioartificial heart. (scielo.br)

others have artificial organs - from increasingly sophisticated prosthetic limbs to bionic eyes and ears. (thefreedictionary.com)

Herein, an overview of the current literature for kidney decellularization and whole-organ recellularization is presented, addressing the pros and cons of the actual techniques already developed, the methods adopted to evaluate the efficacy of the procedures, and the challenges to be overcome in order to achieve an optimal protocol. (frontiersin.org)
Such scaffolds may be produced through the decellularization of whole organs. (ufl.edu)

They can connect the blood vessels of the two artificial organs , thereby modelling not just the organs themselves, but the interactions between them. (thefreedictionary.com)

Despite early clinical applications for the trachea, bladder, skin or heart valves, more solid organs can probably never be transferred to the patient regarding their demanding and complicated engineering process. (confex.com)
Level four was solid organs, which were by far the most complex to recreate due to the vascularity. (wikipedia.org)

Some, like Dr. Macchiarini, want to go even further - to harness the body's repair mechanisms so that it can remake a damaged organ on its own. (nytimes.com)

So far, only a few organs have been made and transplanted, and they are relatively simple, hollow ones - like bladders and Mr. Beyene's windpipe, which was implanted in June 2011. (nytimes.com)

This chair has the ambition, to take-on the challenge of helping the patients by developing (bio) artificial organs. (utwente.nl)
Bioartificial organs' most compelling use may be for kidney failure patients. (technologyreview.com)
The goal of both projects is to develop a new, potentially inexhaustible source of organs that would not require patients to take powerful anti-rejection drugs. (eurekalert.org)

Some of the other factors such as advancement in the medical bionics, rising ageing population, lack of organ donors, and increasing number of road accidents are some of the factors which will drive the bioartificial organ manufacturing market in the forecast period of 2020 to 2027. (pharmiweb.com)
The goal of the research was to test the suitability of pancreata from organ donors as a platform for building a new bio-artificial pancreas. (eurekalert.org)

Anatomy2

Organisms2

Diseases2

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Phenomena and Processes3

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture3

Humanities3

Information Science6

Named Groups1

Health Care5

Geographicals2

Excitability and contractility of skeletal muscle engineered from primary cultures and cell lines. (1/58)

Injectable gels for tissue engineering. (2/58)

Tissue engineering strategies for adipose tissue repair. (3/58)

Tissue engineering in the cardiovascular system: progress toward a tissue engineered heart. (4/58)

Tissue engineering in plastic reconstructive surgery. (5/58)

Engineering of vascular ingrowth matrices: are protein domains an alternative to peptides? (6/58)

Peripheral nerve injury: a review and approach to tissue engineered constructs. (7/58)

Self-assembly and mineralization of peptide-amphiphile nanofibers. (8/58)

Bioartificial Organs

Liver, Artificial

Artificial Organs

Kidneys, Artificial

Liver Failure, Acute

Bioreactors

Liver Failure

Hepatocytes

Tissue Engineering

Extracorporeal Circulation

Pancreas, Artificial

Swine, Miniature

Cell Culture Techniques

Albumins

Equipment Design

Ammonia

Swine

Biocompatible Materials

Prostheses and Implants

Diffusion

Electrodes

Electronics

Transistors, Electronic

Electrodes, Implanted

Patents as Topic

Biosensing Techniques

Massachusetts

Hospitals, General

Boston

Tissue Donors

Hand Transplantation

Organ Transplantation

Tissue Scaffolds

Electrophoresis, Microchip

Cost Savings

Support Vector Machines

Renal Dialysis

Peritoneal Dialysis

Artificial Intelligence

Quality of Life

Congresses as Topic

Genetic Privacy

Longevity

Archives

Genetics, Medical

Beginning of Human Life

Periodicals as Topic

X-Ray Microtomography

Imaging, Three-Dimensional

Dentistry

Tomography, X-Ray Computed

Tooth

Algorithms

Models, Biological

Excitability and contractility of skeletal muscle engineered from primary cultures and cell lines. (1/58)

Injectable gels for tissue engineering. (2/58)

Tissue engineering strategies for adipose tissue repair. (3/58)

Tissue engineering in the cardiovascular system: progress toward a tissue engineered heart. (4/58)

Tissue engineering in plastic reconstructive surgery. (5/58)

Engineering of vascular ingrowth matrices: are protein domains an alternative to peptides? (6/58)

Peripheral nerve injury: a review and approach to tissue engineered constructs. (7/58)

Self-assembly and mineralization of peptide-amphiphile nanofibers. (8/58)

Asia-Pacific Bio-Artificial Pancreas Market Report - Research, Industry Analysis Reports and Market Demands

Patent US5855613 - Retrievable bioartificial implants having dimensions allowing rapid ... - Google Patents

Home | The Kidney Project | UCSF

Philosophical Comment: CROSSPOST: Untangling forgotten tracheal transplants of Heike and Thorsten Walles, who set a lawyer upon...

OPUS 4 | Search

Symposium on Therapeutic Organ Engineering

Bioartificial Renal Assist Device Reduces Risk of Death from Acute Kidney Injury | Medgadget

Bioartificial Heart: A Human-Sized Porcine Model - The Way Ahead - pdf descargar

Special Lecture: Organs on Demand - Solving Chronic Disease with Stem Cells and Organ Engineering - European Forum Alpbach

Generation and transplantation of an autologous vascularized bioartificial human tissue

JCI - Welcome

Overview

HDAC1/2 Inhibitor reduce the risk of cardiovascular - Page 2 of 7

University of Pittsburgh Begins Trial with New Bio-Artificial Liver Device

A Bio-Artificial Kidney Is Being Developed To End The Need For Dialysis | Healthy Food Team

Russian Scientists Created A Bioartificial Liver :: Russia-InfoCentre

The emerging field of cell and tissue engineering<...

Bio)Artificial Organs

風(風邪)強し | わかばテニススクール～wakabaブログ～