Bile ducts. Medical search

The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.

The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.

An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.

Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT.

Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.

Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).

Tumors or cancer of the BILE DUCTS.

Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.

Diseases of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.

Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.

Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.

A benign tumor of the intrahepatic bile ducts.

Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.

Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.

An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.

Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.

Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.

The duct that is connected to the GALLBLADDER and allows the emptying of bile into the COMMON BILE DUCT.

Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).

The largest lymphatic vessel that passes through the chest and drains into the SUBCLAVIAN VEIN.

Excision of the gallbladder through an abdominal incision using a laparoscope.

The BILE DUCTS and the GALLBLADDER.

Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.

Surgical removal of the GALLBLADDER.

Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.

Any surgical procedure performed on the biliary tract.

Application of a ligature to tie a vessel or strangulate a part.

Presence or formation of GALLSTONES in the COMMON BILE DUCT.

Incision of Oddi's sphincter or Vater's ampulla performed by inserting a sphincterotome through an endoscope (DUODENOSCOPE) often following retrograde cholangiography (CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE). Endoscopic treatment by sphincterotomy is the preferred method of treatment for patients with retained or recurrent bile duct stones post-cholecystectomy, and for poor-surgical-risk patients that have the gallbladder still present.

A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.

Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.

Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.

A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

Linear TETRAPYRROLES that give a characteristic color to BILE including: BILIRUBIN; BILIVERDIN; and bilicyanin.

A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.

Minute intercellular channels that occur between liver cells and carry bile towards interlobar bile ducts. Also called bile capillaries.

Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.

Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.

A malignant tumor arising from the epithelium of the BILE DUCTS.

A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.

The sphincter of the hepatopancreatic ampulla within the duodenal papilla. The COMMON BILE DUCT and main pancreatic duct pass through this sphincter.

Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).

A pair of ducts near the WOLFFIAN DUCTS in a developing embryo. In the male embryo, they degenerate with the appearance of testicular ANTI-MULLERIAN HORMONE. In the absence of anti-mullerian hormone, mullerian ducts give rise to the female reproductive tract, including the OVIDUCTS; UTERUS; CERVIX; and VAGINA.

Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.

A congenital anatomic malformation of a bile duct, including cystic dilatation of the extrahepatic bile duct or the large intrahepatic bile duct. Classification is based on the site and type of dilatation. Type I is most common.

FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.

Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

Surgical formation of an opening (stoma) into the COMMON BILE DUCT for drainage or for direct communication with a site in the small intestine, primarily the DUODENUM or JEJUNUM.

The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.

An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.

INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

A bile pigment that is a degradation product of HEME.

Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.

Tumors or cancer of the gallbladder.

The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.

A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.

A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.

Straight tubes commencing in the radiate part of the kidney cortex where they receive the curved ends of the distal convoluted tubules. In the medulla the collecting tubules of each pyramid converge to join a central tube (duct of Bellini) which opens on the summit of the papilla.

Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic).

Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.

A tubular duct that conveys TEARS from the LACRIMAL GLAND to the nose.

Pathological processes of the LIVER.

Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.

A Y-shaped surgical anastomosis of any part of the digestive system which includes the small intestine as the eventual drainage site.

Paired ducts in the human male through which semen is ejaculated into the urethra.

The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.

Excision of all or part of the liver. (Dorland, 28th ed)

The condition of an anatomical structure's being dilated beyond normal dimensions.

A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.

A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function. It may cause skin and kidney damage.

A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.

Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.

Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.

Surgery of the smooth muscle sphincter of the hepatopancreatic ampulla to relieve blocked biliary or pancreatic ducts.

Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.

A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.

Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.

Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.

Endoscopic examination, therapy or surgery of the luminal surface of the duodenum.

Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.

A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.

The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.

A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.

A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.

Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.

Recycling through liver by excretion in bile, reabsorption from intestines (INTESTINAL REABSORPTION) into portal circulation, passage back into liver, and re-excretion in bile.

The condition of an anatomical structure's being constricted beyond normal dimensions.

Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.

Adenocarcinoma of the common hepatic duct bifurcation. These tumors are generally small, sharply localized, and seldom metastasizing. G. Klatskin's original review of 13 cases was published in 1965. Once thought to be relatively uncommon, tumors of the bifurcation of the bile duct now appear to comprise more than one-half of all bile duct cancers. (From Holland et al., Cancer Medicine, 3d ed, p1457)

The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.

A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.

The transference of a part of or an entire liver from one human or animal to another.

An abnormal concretion occurring mostly in the urinary and biliary tracts, usually composed of mineral salts. Also called stones.

Pathological processes of the PANCREAS.

A subclass of ORGANIC ANION TRANSPORTERS whose transport of organic anions is driven either directly or indirectly by a gradient of sodium ions.

A short thick vein formed by union of the superior mesenteric vein and the splenic vein.

Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.

Endoscopic examination, therapy or surgery of the digestive tract.

Infection of the biliary passages with CLONORCHIS SINENSIS, also called Opisthorchis sinensis. It may lead to inflammation of the biliary tract, proliferation of biliary epithelium, progressive portal fibrosis, and sometimes bile duct carcinoma. Extension to the liver may lead to fatty changes and cirrhosis. (From Dorland, 27th ed)

Fragmentation of CALCULI, notably urinary or biliary, by LASER.

Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Congenital cystic dilatation of the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC). It consists of 2 types: simple Caroli disease is characterized by bile duct dilatation (ectasia) alone; and complex Caroli disease is characterized by bile duct dilatation with extensive hepatic fibrosis and portal hypertension (HYPERTENSION, PORTAL). Benign renal tubular ectasia is associated with both types of Caroli disease.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

The narrow tube connecting the YOLK SAC with the midgut of the EMBRYO; persistence of all or part of it in post-fetal life produces abnormalities, of which the commonest is MECKEL DIVERTICULUM.

The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed.

Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously.

An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)

Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.

Establishment of an opening into the gallbladder either for drainage or surgical communication with another part of the digestive tract, usually the duodenum or jejunum.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Interference with the secretion of tears by the lacrimal glands. Obstruction of the LACRIMAL SAC or NASOLACRIMAL DUCT causing acute or chronic inflammation of the lacrimal sac (DACRYOCYSTITIS). It is caused also in infants by failure of the nasolacrimal duct to open into the inferior meatus and occurs about the third week of life. In adults occlusion may occur spontaneously or after injury or nasal disease. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p250)

The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

Radiography of the gallbladder after ingestion of a contrast medium.

The part of the membranous labyrinth that traverses the bony vestibular aqueduct and emerges through the bone of posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) where it expands into a blind pouch called the endolymphatic sac.

A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Organic or functional motility disorder involving the SPHINCTER OF ODDI and associated with biliary COLIC. Pathological changes are most often seen in the COMMON BILE DUCT sphincter, and less commonly the PANCREATIC DUCT sphincter.

Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.

One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.

The act of dilating.

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.

Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).

Elements of limited time intervals, contributing to particular results or situations.

A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.

Tumors or cancer of the LIVER.

Presence or formation of GALLSTONES in the GALLBLADDER.

Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.

Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.

A peptide hormone of about 27 amino acids from the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level. (USAN and the USP Dictionary of Drug Names, 1994, p597)

A genus of trematode liver flukes of the family Opisthorchidae. It consists of the following species: O. felineus, O. noverca (Amphimerus noverca), and O. viverrini. The intermediate hosts are snails, fish, and AMPHIBIANS.

Infection with flukes of the genus Opisthorchis.

A species of trematode flukes of the family Opisthorchidae. Many authorities consider this genus belonging to Opisthorchis. It is common in China and other Asiatic countries. Snails and fish are the intermediate hosts.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.

INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.

A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.

Tumors or cancer of the DUODENUM.

A spiral tube that is firmly suspended in the bony shell-shaped part of the cochlea. This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) thus dividing the PERILYMPH-filled spiral canal into two channels, the SCALA VESTIBULI and the SCALA TYMPANI.

The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.

A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)

Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)

An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.

INFLAMMATION of the LIVER.

An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

A malignant epithelial tumor with a glandular organization.

A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.

Endoscopes for examining the interior of the duodenum.

The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces.

A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.

Cholestanes substituted in any position with one or more hydroxy groups. They are found in feces and bile. In contrast to bile acids and salts, they are not reabsorbed.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.

A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)

Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.

A semisynthetic bile acid made from cholic acid. It is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid.

Hemorrhage in or through the BILIARY TRACT due to trauma, inflammation, CHOLELITHIASIS, vascular disease, or neoplasms.

Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.

Operation for biliary atresia by anastomosis of the bile ducts into the jejunum or duodenum.

Repair or renewal of hepatic tissue.

Abdominal symptoms after removal of the GALLBLADDER. The common postoperative symptoms are often the same as those present before the operation, such as COLIC, bloating, NAUSEA, and VOMITING. There is pain on palpation of the right upper quadrant and sometimes JAUNDICE. The term is often used, inaccurately, to describe such postoperative symptoms not due to gallbladder removal.

The period during a surgical operation.

Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.

A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.

A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.

Membrane transporters that co-transport two or more dissimilar molecules in the same direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.

A species of helminth commonly called the sheep liver fluke. It occurs in the biliary passages, liver, and gallbladder during various stages of development. Snails and aquatic vegetation are the intermediate hosts. Occasionally seen in man, it is most common in sheep and cattle.

Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.

The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)

A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.

Uptake of substances through the lining of the INTESTINES.

A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).

Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)

Tumors or cancer of the DIGESTIVE SYSTEM.

The circulation of BLOOD through the LIVER.

A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.

The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.

The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.

An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.

A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

Hand-held tools or implements used by health professionals for the performance of surgical tasks.

A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)

A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.

Bile duct epithelial cells exposed to alpha-naphthylisothiocyanate produce a factor that causes neutrophil-dependent hepatocellular injury in vitro. (1/1207)

The acute hepatotoxicity induced by alpha-naphthylisothiocyanate (ANIT) in rats is manifested as neutrophil-dependent necrosis of bile duct epithelial cells (BDECs) and hepatic parenchymal cells. This hepatotoxicity mirrors that of drug-induced cholangiolitic hepatitis in humans. Since BDECs are primary targets of ANIT-induced toxicity, we hypothesized that after exposure to ANIT, BDECs produce a factor(s) that causes neutrophil chemotaxis and neutrophil-dependent hepatocellular injury. To test this hypothesis BDECs were isolated from male Sprague Dawley rats and incubated with ANIT (6.25, 12.5, 25, or 50 microM) or vehicle for 24 h. The conditioned medium (CM) was collected and placed in the bottom chamber of a two-chambered chemotaxis system, while isolated neutrophils were placed in the top chamber. Chemotaxis was indicated by neutrophil migration through a membrane to the bottom chamber. CM from BDECs exposed to each concentration of ANIT was chemotactic, whereas CM from vehicle-treated BDECs was not. ANIT alone caused a modest degree of chemotaxis at 50 microM. The conditioned media were added to isolated hepatocytes or to hepatocyte-neutrophil cocultures and incubated for 24 h. Hepatocyte toxicity was indicated by alanine aminotransferase release into the culture medium. CM from vehicle-treated BDECs did not cause hepatocyte killing in either hepatocyte-neutrophil cocultures or hepatocyte cultures. In contrast, the addition of CM from ANIT-treated BDECs (CM-BDEC-A) to hepatocyte-neutrophil cocultures resulted in hepatocyte killing. The same CM was not cytotoxic to hepatocyte cultures devoid of neutrophils. The hepatocyte killing could not be explained by residual ANIT in the CM, which was below the limit of detection (< or = 0.5 microM). The addition of antiproteases afforded protection against neutrophil-dependent hepatocellular injury induced by CM-BDEC-A. These results indicate that ANIT causes BDECs to release a factor(s) that attracts neutrophils and stimulates them to injure hepatocytes in vitro. (+info)

Transfer of the 1-pro-R and the 1-pro-S hydrogen atoms of ethanol in metabolic reductions in vivo. (2/1207)

The transfer of deuterium from [1 R-2H]ethanol and [1 S-2H]-ethanol to reduced metabolites of administered compounds was measured in female rats provided with bile fistulas. Administered cyclohexanone was reduced to cyclohexanol, and in this reduction hydrogen was transferred only from the 1-pro-R position of the ethanol. The deuterium content in the cyclohexanol was about 67% of that in the ethanol. In the reduction of the 17-oxo group in 3beta-hydroxy-5alpha-androstan-17-one, hydrogen was transferred both from the 1-pro-R position and the 1-pro-S position, resulting in degrees of labelling that were about 25% and 2%, respectively, of those in the specific positions of the ethanols. The 1-pro-R and 1-pro-S positions of ethanol contributed about 9% and 5%, respectively, of the 3beta hydrogen in lithocholic acid formed from 3-oxo-5beta-cholanoic acid. The results indicate that alcohol dehydrogenase and aldehyde dehydrogenase do not share a common pool of NAD, and that NADH formed during acetaldehyde oxidation is utilized for reductions in the cytosol to a smaller extent than the NADH formed in the alcohol dehydrogenase reaction. This result supports the concept that aldehyde oxidation is mainly an intramitochondrial process. The relatively extensive utilization of the 1-pro-S hydrogen of ethanol in the reduction of 3-oxo-5beta-cholanoic acid, that is probably NADPH-dependent, indicates that cytosolic NADPH may be produced from malate or isocitrate formed intramitochondrially. (+info)

Effect of its demethylated metabolite on the pharmacokinetics of unchanged TAK-603, a new antirheumatic agent, in rats. (3/1207)

A factor in the dose-dependent pharmacokinetics of ethyl 4-(3, 4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2, 4-triazol-1-yl-methyl)quinoline-3-carboxylate (TAK-603) in rats was shown to be due to the inhibition of metabolic clearance of unchanged TAK-603 by its major metabolite, M-I, in other words, product inhibition. The effect of M-I on the metabolic clearance of TAK-603 was studied using rats continuously infused i.v. with this metabolite at rates of 5.3 and 16.0 mg/h/kg. The total body clearance of TAK-603 was decreased remarkably in M-I-infused rats, and the decline of total body clearance depended on the steady-state plasma concentrations of M-I. The effect of M-I generated from the dosed parent drug on the plasma concentration-time profile of TAK-603 was investigated using bile-cannulated rats after i.v. injection of 14C-labeled TAK-603 at doses of 1 and 15 mg/kg. Elimination rates of TAK-603 from rat plasma increased in the bile-cannulated rats in which systemic M-I levels were reduced by interrupting its enterohepatic circulation. To express, simultaneously, the relationships between TAK-603 and M-I in plasma concentration-time profiles, a kinetic model based on the product inhibition was developed for the bile-cannulated rats. A good agreement between calculated curves and the observed concentrations of both TAK-603 and M-I was found at 1 and 15 mg/kg, and the calculated curves were drawn using constant parameters for the two dosages. These results show that the product inhibition by M-I is one factor responsible for the dose-dependent pharmacokinetics of TAK-603 in rats. (+info)

Complications of cholecystectomy: risks of the laparoscopic approach and protective effects of operative cholangiography: a population-based study. (4/1207)

BACKGROUND: Previous studies suggest that laparoscopic cholecystectomy (LC) is associated with an increased risk of intraoperative injury involving the bile ducts, bowel, and vascular structures compared with open cholecystectomy (OC). Population-based studies are required to estimate the magnitude of the increased risk, to determine whether this is changing over time, and to identify ways by which this might be reduced. METHODS: Suspected cases of intraoperative injury associated with cholecystectomy in Western Australia in the period 1988 to 1994 were identified from routinely collected hospital statistical records and lists of persons undergoing postoperative endoscopic retrograde cholangiopancreatography. The case records of suspect cases were reviewed to confirm the nature and site of injury. Ordinal logistic regression was used to estimate the risk of injury associated with LC compared with OC after adjusting for confounding factors. RESULTS: After the introduction of LC in 1991, the proportion of all cholecystectomy cases with intraoperative injury increased from 0.67% in 1988-90 to 1.33% in 1993-94. Similar relative increases were observed in bile duct injuries, major bile leaks, and other injuries to bowel or vascular structures. Increases in intraoperative injury were observed in both LC and OC. After adjustment for age, gender, hospital type, severity of disease, intraoperative cholangiography, and calendar period, the odds ratio for intraoperative injury in LC compared with OC was 1.79. Operative cholangiography significantly reduced the risk of injury. CONCLUSION: Operative cholangiography has a protective effect for complications of cholecystectomy. Compared with OC, LC carries a nearly twofold higher risk of major bile, vascular, and bowel complications. Further study is required to determine the extent to which potentially preventable factors contribute to this risk. (+info)

Investigation of bile ducts before laparoscopic cholecystectomy. (5/1207)

BACKGROUND: Since the advent of laparoscopic cholecystectomy, there has been controversy about the investigation of the bile ducts and the management of common bile duct stones. Routine peroperative cholangiography (POC) in all cases has been recommended. We have adopted a policy of not performing routine POC, and the results of 700 cases are reported. METHODS: Since 1990, all patients have undergone preoperative ultrasound scan. We have performed selective preoperative endoscopic retrograde cholangiopancreatography (ERCP) because of a clinical history of jaundice and/or pancreatitis, abnormal liver function tests and ultrasound evidence of dilated bile ducts (N=78, 11.1%). The remaining 622 patients did not have a routine POC, but selective peroperative cholangiogram (POC) was performed only in 42 patients (6%) because of unsuccessful ERCP or mild alteration in the criteria for the presence of bile duct stones. The remaining 580 patients did not undergo POC. Careful dissection of Calot's triangle was performed in all cases to reduce the risk of bile duct injuries. RESULTS: The overall operative complications, postoperative morbidity and mortality was 1.71%, 2.14% and 0.43%, respectively. Bile duct injuries occurred in two patients (0.26%) and both were recognized during the operation and repaired. There was a single incidence of retained stone in this series of 700 cases (0.14%), which required postoperative ERCP. CONCLUSIONS: This policy of selective preoperative ERCP, and not routine peroperative cholangiogram, is cost effective and not associated with significant incidence of retained stones or bile duct injuries after laparoscopic cholecystectomy. (+info)

Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver. (6/1207)

Bile duct damage and/or loss is limited to a range of duct sizes in cholangiopathies. We tested the hypothesis that CCl4 damages only large ducts. CCl4 or mineral oil was given to bile duct-ligated (BDL) rats, and 1, 2, and 7 days later small and large cholangiocytes were purified and evaluated for apoptosis, proliferation, and secretion. In situ, we measured apoptosis by morphometric and TUNEL analysis and the number of small and large ducts by morphometry. Two days after CCl4 administration, we found an increased number of small ducts and reduced number of large ducts. In vitro apoptosis was observed only in large cholangiocytes, and this was accompanied by loss of proliferation and secretion in large cholangiocytes and loss of choleretic effect of secretin. Small cholangiocytes de novo express the secretin receptor gene and secretin-induced cAMP response. Consistent with damage of large ducts, we detected cytochrome P-4502E1 (which CCl4 converts to its radicals) only in large cholangiocytes. CCl4 induces selective apoptosis of large ducts associated with loss of large cholangiocyte proliferation and secretion. (+info)

Aquaporin water channels in gastrointestinal physiology. (7/1207)

Fluid transport is a major function of the gastrointestinal (GI) tract with more than 9 litres of fluid being absorbed or secreted across epithelia in human salivary gland, stomach, the hepatobiliary tract, pancreas, small intestine and colon. This review evaluates the evidence that aquaporin-type water channels are involved in GI fluid transport. The aquaporins are a family of small ( approximately 30 kDa) integral membrane proteins that function as water channels. At least seven aquaporins are expressed in various tissues in the GI tract: AQP1 in intrahepatic cholangiocytes, AQP4 in gastric parietal cells, AQP3 and AQP4 in colonic surface epithelium, AQP5 in salivary gland, AQP7 in small intestine, AQP8 in liver, pancreas and colon, and AQP9 in liver. There are functional data suggesting that some GI cell types expressing aquaporins have high or regulated water permeability; however, there has been no direct evidence for a role of aquaporins in GI physiology. Recently, transgenic mice have been generated with selective deletions of various aquaporins. Preliminary evaluation of GI function suggests a role for AQP1 in dietary fat processing and AQP4 in colonic fluid absorption. Further study of aquaporin function in the GI tract should provide new insights into normal GI physiology and disease mechanisms, and may yield novel therapies to regulate fluid movement in GI diseases. (+info)

Dihydropyrimidine dehydrogenase activity and fluorouracil pharmacokinetics with liver damage induced by bile duct ligation in rats. (8/1207)

Hepatic metabolism is the main determinant in the pharmacokinetics of 5-fluorouracil (5-FU). Its disposition might be affected with liver dysfunction. In the present study, the influence of liver damage induced by bile duct ligation on dihydropyrimidine dehydrogenase (DPD), a rate-limiting enzyme in 5-FU catabolism, CYP2B, and 5-FU pharmacokinetics were compared in male Sprague-Dawley rats. After 3 weeks of the ligation in two different groups of animals for in vitro and pharmacokinetic experiments, significant increases in serum bilirubin level and spleen weight were found in both groups. No significant differences were noted in bilirubin level or spleen weight of the bile duct ligation group between the two experiment groups. In the in vitro experiment, DPD activity and protein levels determined by Western blot analysis in the bile duct ligation group were slightly but significantly greater than those of a sham-operated group, whereas CYP2B activity and protein level were significantly reduced. These findings were supported by mRNA levels of CYP2B and DPD. When 40 mg/kg 5-FU was administered i.v. in the pharmacokinetic experiment, no significant differences in pharmacokinetic parameters were found between the bile duct ligation and sham-operated groups. These results suggested that DPD activity and protein level were maintained and that 5-FU pharmacokinetics was not altered in the presence of liver damage accompanied by a significant reduction in CYP2B activity and protein level, supporting previous clinical studies showing that mild to moderate liver dysfunction does not affect 5-FU disposition. (+info)

Diseases of the pancreas, gall bladder, bile duct[edit]. Primary biliary cirrhosis. CD is prevalent in primary biliary ...

https://en.wikipedia.org/wiki/Gluten-sensitive_enteropathy_associated_conditions

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Lactose_intolerance

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ... Poor feeding, bloating, decreased activity, vomiting of bile[1]. Complications. Short-gut syndrome, intestinal strictures, ...

https://en.wikipedia.org/wiki/Necrotizing_enterocolitis

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Spigelian_hernia

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Bacillary_dysentery

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ... The pain and discomfort that a patient experiences is due to the reflux of gastric acid, air, or bile. While there are several ...

https://en.wikipedia.org/wiki/Hiatal_hernia

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Adhesion_

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Montezuma's_Revenge_

Bile duct. Identifiers. IUPAC name. *. 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13 ... Biodistribution of 14C-labelled docetaxel in three patients showed the bulk of the drug to be metabolised and excreted in bile ...

https://en.wikipedia.org/wiki/Docetaxel

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ... Gallstones, which can impede the flow of bile into the duodenum, which can affect the ability to neutralize gastric acid[ ...

https://en.wikipedia.org/wiki/GERD

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Diverticulosis

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Intestinal_obstruction

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Collagenous_colitis

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Pancreatic_abscess

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Peptic_ulcer_disease

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Mesenteric_ischemia

Bile duct cancerEdit. Main article: Bile duct cancer. A review of the literature found that there is no association between ...

https://en.m.wikipedia.org/wiki/Alcohol_and_cancer

kidney, bile duct. Identifiers. IUPAC name. *. (±)-cis-4-amino-5-chloro-N-(1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4- ...

https://en.wikipedia.org/wiki/Cisapride

Swelling of the bile duct *^ a b c A potentially fatal skin reaction ...

https://en.wikipedia.org/wiki/Sorafenib

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Amoebic_liver_abscesses

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Esophageal_motility_disorder

... leading to the contraction and release of bile into the bile ducts. Other hormones allow for the relaxation and further storing ... and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts ... Estrogens increase cholesterol secretion and diminish bile salt secretion, while progestins act by reducing bile salt secretion ... is used in both the diagnosis and treatment as it can remove the stones that are blocking the bile ducts causing ...

https://en.wikipedia.org/wiki/Gallbladder_disease

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Hepatic_encephalopathy

Bile duct/ Other biliary tree. *Cholangitis *Primary sclerosing cholangitis. *Secondary sclerosing cholangitis ... bile, and small intestine and pancreatic contents cause damage to the cells of the lower esophagus. Recently, bile acids were ... Gong L, Debruyne PR, Witek M, Nielsen K, Snook A, Lin JE, Bombonati A, Palazzo J, Schulz S, Waldman SA (2009). "Bile acids ... "Bile acids induce ectopic expression of intestinal guanylyl cyclase C through nuclear factor-kappaB and Cdx2 in human ...

https://en.wikipedia.org/wiki/Barrett's_esophagitis

Bile duct involvement. No increase in rate of primary sclerosing cholangitis. Higher rate[64] ... Liver function tests are performed to screen for bile duct involvement: primary sclerosing cholangitis. ... bile duct cancer).[28][24] PSC is a progressive condition, and may result in cirrhosis of the liver.[24] No specific therapy ... a progressive inflammatory disorder of small and large bile ducts. Up to 70-90% of people with primary sclerosing cholangitis ...

https://en.wikipedia.org/wiki/Ulcerative_colitis

Berci, G.; Cuschieri, A. (1996). Bile Ducts and Bile Duct Stones. Philadelphia: Saunders. "Alfred Cuschieri" (PDF). Retrieved ... Cuschieri, A.; Berci, G. (1984). Common Bile Duct Exploration. Boston: Martinus Nijhoff. Berci, G.; Cuschieri, A. (1986). ...

https://en.wikipedia.org/wiki/Alfred_Cuschieri

... , also known as bile duct cancer, is a type of cancer that forms in the bile ducts. Symptoms of ... American Cancer Society Detailed Guide to Bile Duct Cancer. Patient information on extrahepatic bile duct tumors, from the ... Tumors occurring in the bile ducts within the liver are referred to as intrahepatic, those occurring in the ducts outside the ... Chronic inflammation and obstruction of the bile ducts, and the resulting impaired bile flow, are thought to play a role in ...

https://en.wikipedia.org/wiki/Cholangiocarcinoma

Extrahepatic bile duct cancer. *Gallbladder cancer. *Gastric (stomach) cancer. *Gastrointestinal carcinoid tumor ... which suggests that it has originated in the milk ducts.[citation needed] ...

https://en.wikipedia.org/wiki/List_of_cancer_types

Treatment of choice is bile duct excision. Reason for surgery is significant risk of malignancy and symptomatic relief of ... with minimal dilatation of Bile duct (6-10mm) in children and associated biliary and/ or pancreatic symptoms. ...

https://en.wikipedia.org/wiki/Forme_fruste

... common bile duct stones, or inflammation of the common bile duct. More than 90% of the time acute cholecystitis is from ... alternate or additional diagnoses should be considered such as gallstone blocking the common bile duct (common bile duct stone ... Diseases of the Gallbladder and Bile Ducts. In Longo D.L., Fauci A.S., Kasper D.L., Hauser S.L., Jameson J, Loscalzo J (Eds), ... Blockage of the cystic duct by a gallstone causes a buildup of bile in the gallbladder and increased pressure within the ...

https://en.wikipedia.org/wiki/Cholecystitis

... a bile acid-sensitive ion channel highly expressed in bile ducts". FASEB J. 26 (10): 4122-30. doi:10.1096/fj.12-207043. PMID ... Primary bile acidsEdit. Bile acid synthesis occurs in liver cells, which synthesize primary bile acids (cholic acid and ... These conjugated bile acids are often referred to as bile salts. The pKa of the unconjugated bile acids are between 5 and 6.5,[ ... Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. Diverse bile acids are ...

https://en.m.wikipedia.org/wiki/Bile_acids

... blockage of the bile duct) ।[୫] ବିକଶିତ ଦେଶମାନଙ୍କରେ ଏହା ପିତ୍ତନଳୀ ଅବରୋଧ ବା ଔଷଧ ଯୋଗୁ ହେଉଥିବା ବେଳେ ବିକାଶଶୀଳ ଦେଶମାନଙ୍କରେ ଏହା ଭୁତାଣୁ ...

https://or.wikipedia.org/wiki/ଜଣ୍ଡିସ୍

Talk:Bile. *Talk:Bile duct. *Talk:Sue Black (anthropologist). *Talk:Blaschko's lines ...

https://en.wikipedia.org/wiki/Category:Mid-importance_Anatomy_articles

Gallbladder, bile duct. *Cholecystectomy. *Cholecystostomy. *ERCP. *Hepatoportoenterostomy. *Medical imaging: Cholangiography * ...

https://en.wikipedia.org/wiki/Rectal_examination

Bile duct/. other biliary tree. Cholangitis (PSC, Secondary sclerosing cholangitis, Ascending) · Cholestasis/Mirizzi's syndrome ...

https://ta.wikipedia.org/wiki/சொளிங்கர்-எலிசன்_கூட்டறிகுறி

It may be caused by a blockage of the bile ducts which release bile salts and pigment into the intestines. The bile then gets ... mixed with blood and this gives a yellow colour to the skin.[3] The blockage of the bile ducts could be caused by: *gallstones ... The bile, made by the liver, is a vital digestive fluid needed for proper nutrition. It also stops decaying changes in food. If ... The yellow colour of the skin and mucous membranes happens because of an increase in the bile pigment, bilirubin, in the blood. ...

https://simple.wikipedia.org/wiki/Jaundice

Presence of gallstones in the common bile duct is called choledocholithiasis, from the Greek chol- (bile) + docho- (duct) + ... bile) + ang- (vessel) + itis- (inflammation), a serious infection of the bile ducts. Gallstones within the ampulla of Vater can ... Gallstone disease refers to the condition where gallstones are either in the gallbladder or common bile duct.[5] The presence ... Experimental investigation of the flow of bile in patient specific cystic duct models M Al-Atabi, SB Chin…, Journal of ...

https://en.m.wikipedia.org/wiki/Gallstones

bile. A dark green to yellowish-brown fluid, produced by the liver of most vertebrates, which aids the digestion of lipids in ... A gland of the animalian endocrine system that secretes hormones directly into the blood rather than through a duct. In humans ...

https://en.m.wikipedia.org/wiki/Glossary_of_biology

... , also known as bile duct cancer, is a type of cancer that forms in the bile ducts.[2] Symptoms of ... American Cancer Society Detailed Guide to Bile Duct Cancer.. *Patient information on extrahepatic bile duct tumors, from the ... ERCP image of cholangiocarcinoma, showing common bile duct stricture and dilation of the proximal common bile duct ... Tumors occurring in the bile ducts within the liver are referred to as intrahepatic, those occurring in the ducts outside the ...

https://en.m.wikipedia.org/wiki/Cholangiocarcinoma

This duct joins with the cystic duct to connect in a common bile duct with the gallbladder. Bile is stored in the gallbladder ... Bile flows from the liver through the bile ducts and into the gall bladder for storage. The bile is released in response to ... It connects to the duodenum via the pancreatic duct which it joins near to the bile duct's connection where both the bile and ... so that it can discharge its bile into the bile duct. The gallbladder needs to store bile in a natural, semi-liquid form at all ...

https://en.wikipedia.org/wiki/Digestive_system

Other causes of KF rings are cholestasis (obstruction of the bile ducts), primary biliary cirrhosis and "cryptogenic" cirrhosis ...

https://en.wikipedia.org/wiki/Kayser–Fleischer_ring

... including the gallbladder and bile ducts. The image produced by this type of medical imaging, called a cholescintigram, is also ... where it is excreted into the bile ducts and stored by the gallbladder[1] until released into the duodenum. ... If the gallbladder is not visualized within 4 hours after the injection, this indicates either cholecystitis or cystic duct ...

https://en.wikipedia.org/wiki/Cholescintigraphy

An important function is the production and control of bile acids. Too much bile acid can be toxic to cells and its synthesis ... The effect of vasopressin on the kidney tubules is to reabsorb water from the distal convoluted tubules and collecting ducts, ... Palmer, LG; Frindt, G (2000). "Aldosterone and potassium secretion by the cortical collecting duct". Kidney International. 57 ( ... Aldosterone acts primarily on the distal convoluted tubules and collecting ducts of the kidneys, stimulating the excretion of ...

https://en.wikipedia.org/wiki/Human_homeostasis

... bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.[11] ... can lead to myoepithelium contraction which causes the expulsion of secretions from the secretory acinus into the ducts and ...

https://en.wikipedia.org/wiki/Saliva

Gallbladder, bile duct. *Cholecystectomy. *Cholecystostomy. *ERCP. *Hepatoportoenterostomy. *Medical imaging: Cholangiography * ...

https://en.wikipedia.org/wiki/Proctoscopy

bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ...

https://en.wikipedia.org/wiki/Gastrointestinal_carcinoid_tumor

6,0 6,1 «SEER Stat Fact Sheets: Liver and Intrahepatic Bile Duct Cancer»։ NCI։ Արխիվացված օրիգինալից 2017-07-28-ին։ Վերցված է ...

https://hy.wikipedia.org/wiki/Լյարդի_քաղցկեղ

Dormia baskets, which are metal baskets used to remove stones from the common bile duct in a procedure known as endoscopic ...

https://en.wikipedia.org/wiki/Esophageal_food_bolus_obstruction

... at the age of 74 due to complications related to bile duct cancer.[101] Robby Krieger and John Densmore, the two remaining ...

https://en.wikipedia.org/wiki/The_Doors

... an infection of the bile duct, or an intestinal infarction.[10] A pierced internal organ (free air on an abdominal x-ray or CT ... Impaired utilization of oxygen in the liver impairs bile salt transport, causing jaundice (yellowish discoloration of skin). In ...

https://en.wikipedia.org/wiki/Sepsis

... or blockage of the bile duct. In the developed world, the cause is more often blockage of the bile duct or medications while in ... can live in the common bile duct, causing obstructive jaundice. Other causes include strictures of the common bile duct, ... with the enlarged gallbladder squeezing on the common hepatic duct). In complete obstruction of the bile duct, no urobilinogen ... Blockage of the bile duct may occur due to gallstones, cancer, or pancreatitis. Medical imaging such as ultrasound is useful ...

https://en.wikipedia.org/wiki/Jaundice

Gallbladder, bile duct. *Cholecystectomy. *Cholecystostomy. *ERCP. *Hepatoportoenterostomy. *Medical imaging: Cholangiography * ...

https://en.wikipedia.org/wiki/Barium_meal

K83.3) Fistula of bile duct *Biliary fistula: connecting the bile ducts to the skin surface, often caused by gallbladder ...

https://en.wikipedia.org/wiki/Fistula

Ing kundilat a duct at ing common bile duct lulub la keng palalam na ning duodenum, at karaniwan yang mayayaus a ... Iting dake ning duodenum atin ya naman minor duodenal papilla, ing bukana ning accessory pancreatic duct. Ing kantu ning ... hepatopancreatic duct (o kaya kundilat a duct king United States), kapamilatan ning pun duodenal papilla. ...

https://pam.m.wikipedia.org/wiki/Duodenum

... indicating that little amount of drug is transferred to the milk duct during breast milk formation. ... primarily originating from bile secretion.[citation needed] ...

https://en.wikipedia.org/wiki/Prilosec

... and cancer can result in bile duct problems. Discover the types, causes, symptoms, and treatment of bile duct diseases. ... your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps ... Different diseases can block the bile ducts and cause a problem with the flow of bile:. *Gallstones, which can increase ... ClinicalTrials.gov: Bile Duct Diseases (National Institutes of Health) * ClinicalTrials.gov: Cholangitis (National Institutes ...

https://medlineplus.gov/bileductdiseases.html

Intrahepatic bile duct cancers (those starting within the liver). *Perihilar (hilar) bile duct cancers (those starting in the ... No matter where they are, nearly all bile duct cancers start in the innermost layer of the wall of the bile duct (called the ... Distal bile duct cancers (those starting farther down the bile duct system) ... Over time they can grow through the wall toward the outside of the bile duct. If a tumor grows through the bile duct wall, it ...

https://www.cancer.org/cancer/bile-duct-cancer/detection-diagnosis-staging/staging.html

Many small ducts drain into the right and left hepatic ducts, which unite to form the main bile duct, the common hepatic duct. ... any of the ducts that convey bile from the liver. ... bile duct n. any of the ducts that convey bile from the liver. ... Many small ducts drain into the right and left hepatic ducts, which unite to form the main bile duct, the common hepatic duct. ... bile duct • n. the duct that conveys bile from the liver and the gallbladder to the duodenum. ...

https://www.encyclopedia.com/medicine/anatomy-and-physiology/anatomy-and-physiology/bile-duct

Learn about bile duct cancer tests, diagnosis, treatment, and survival rates. ... Bile duct cancer can be caused by liver diseases or colitis. ... your gallbladder pushes the bile into tubes called bile ducts. ... Bile duct cancer is rare. It can happen in the parts of the bile ducts that are outside or inside the liver. Cancer of the bile ... How Is Bile Duct Cancer Diagnosed? (American Cancer Society) * Stages of Extrahepatic Bile Duct Cancer (National Cancer ...

https://medlineplus.gov/bileductcancer.html

Learn how intrahepatic bile duct cancer is staged. ... Determining the stage of bile duct cancer helps doctors decide ... Staging of Intrahepatic Bile Duct Cancers. After a person is diagnosed with intrahepatic bile duct cancer, doctors will try to ... Distal Bile Duct Cancer Stages (for cancers starting farther down the bile duct) ... Staging systems for cancers starting in other parts of the bile ducts are described in:. *Perihilar Bile Duct Cancer Stages ( ...

https://www.cancer.org/cancer/bile-duct-cancer/detection-diagnosis-staging/staging/staging-intrahepatic-bile-duct.html

... is used to examine the bile duct and pancreatic ducts for the presence of gallstones, tumours, or inflammation. In this ... Other articles where Bile duct is discussed: endoscopic retrograde cholangiopancreatoscopy: … ... The common bile duct averages about 10 cm in length, and flow of bile from its lower end into the intestine is controlled by ... is used to examine the bile duct and pancreatic ducts for the presence of gallstones, tumours, or inflammation. In this ...

https://www.britannica.com/science/bile-duct

Bile Duct Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Hepatic Duct Sclerosing Cholangitis These keywords were ... 1992) Mechnisms of major bile duct injury during laparoscopic cholecystectomy. Ann Surg 215: 196-202PubMedGoogle Scholar ... Sussman SK, Hall FM, Elboim CM (1986) Radiographic assessment of anomalous bile ducts. Gastrointest Radiol 11: 269-272PubMed ... Desmet VJ (1992) Vanishing bile duct disorders. Prog Liver Dis 10: 89-121PubMedGoogle Scholar ...

https://link.springer.com/chapter/10.1007/3-540-30971-3_3

... surgical bile duct exploration, percutaneous approach to the bile duct, or long-term bile duct stenting should be discussed ... bile duct stones, intrahepatic stones, or impacted stones in the bile duct or cystic duct. The initial approach to the removal ... bile duct stones may be difficult to remove due to challenging access to the bile duct (periampullary diverticulum, Billroth II ... two or more bile duct stents should be inserted, and ursodiol added to aid in duct decompression, stone fragmentation, and ...

https://www.ncbi.nlm.nih.gov/pubmed/16539873

... usually develops in the bile duct system that arises from the liver and bile ducts and ends at the small intestine. Cancer that ... develops in the section of bile ducts within and outside the liver is called as intrahepatic and hilar cholangiocarcinoma, ... Distal cholangiocarcinoma is developed in the bile section that is associated with small intestine. Prognostic factors of ... Cholangiocarcinoma (bile duct cancer) usually develops in the bile duct system that arises from the liver and bile ducts and ...

https://www.news-medical.net/health/Bile-Duct-Cancer-Prognosis.aspx

... and staged with the help of tests that analyze bile ducts and neighboring organs. It is essential to be aware whether the bile ... duct can be detached by surgery, when planning for treatment. To find, diagnose, and confirm bile duct cancer; tests and ... Understanding Liver and Bile Duct Cancer. Play. Biopsies for Bile Duct Cancer. Needle biopsy: In this method, without making a ... Bile duct cancer is identified, diagnosed, and staged with the help of tests that analyze bile ducts and neighboring organs. It ...

https://www.news-medical.net/health/Test-for-Bile-Duct-Cancer.aspx

Bile duct damage. The bile ducts carry bile from your liver to your small intestine. When bile ducts become damaged, bile can ...

https://www.mayoclinic.org/diseases-conditions/primary-biliary-cholangitis-pbc/multimedia/bile-duct-damage/img-20007458

3) that arise in the gallbladder and migrate down the cystic duct. Depending on geographic variation in this incidence of... ... The majority of bile duct stones are secondary bile duct stones (Chap. ... The majority of bile duct stones are secondary bile duct stones (Chap. 3) that arise in the gallbladder and migrate down the ... Primary duct closure verses T-tube drainage following exploration of the common bile duct. Aust N Z J Surg. 1994;64:823-6. ...

https://link.springer.com/chapter/10.1007%2F978-3-319-63884-3_20

The interlobular bile ducts (or interlobular ductules) carry bile in the liver between the Canals of Hering and the interlobar ... STRAZZABOSCO, MARIO; FABRIS, LUCA (2008-06-01). "Functional Anatomy of Normal Bile Ducts". Anatomical Record. 291 (6): 653-660 ... bile ducts. They are part of the interlobular portal triad and can be easily localized by looking for the much larger portal ... The cells of the ducts are described as cuboidal epithelium with increasing amounts of connective tissue around it. ...

https://en.wikipedia.org/wiki/Interlobular_bile_ducts

Interlobular bile ducts (between the interlobar ducts and the lobules) - simple columnar epithelium. Intralobular bile ducts ( ... Intrahepatic bile ducts compose the outflow system of exocrine bile product from the liver. They can be divided into: Lobar ... Interlobar ducts (between the main hepatic ducts and the interlobular ducts) - pseudostratified columnar epithelium. ... ducts (right and left hepatic ducts) - stratified columnar epithelium. ...

https://en.wikipedia.org/wiki/Intrahepatic_bile_ducts

Role of β-catenin in development of bile ducts.. Cordi S1, Godard C2, Saandi T1, Jacquemin P1, Monga SP3, Colnot S2, Lemaigre ... However, its role in development of bile ducts has not yet been addressed. Here we used stage-specific in vivo gain- and loss- ... Beta-catenin is dispensable for bile duct morphogenesis. (A) After injection of tamoxifen at E14.5, inactivation of β-catenin ... Second, when β-catenin was depleted in the latter, maturation of cholangiocytes, bile duct morphogenesis and differentiation of ...

https://www.ncbi.nlm.nih.gov/pubmed/26856660

Unfortunately, most benign bile duct strictures (biliary strictures) are iatrogenic, resulting from operative trauma (see ... Bile duct stricture (biliary stricture) is an uncommon but challenging clinical condition that requires a coordinated ... the exact prevalence of bile duct strictures is unknown. One major category of bile duct strictures is postoperative bile duct ... causing a narrowing of the bile duct lumen and obstructing the flow of bile) or extrinsic compression of the bile ducts by a ...

https://emedicine.medscape.com/article/186850-overview

dilated Common bile duct renato126 Hi im 36 years old and had been in the ER 2x for abdominal pain, all my labs were normal ... dilated Common bile duct. Hi im 36 years old and had been in the ER 2x for abdominal pain, all my labs were normal including ...

https://www.medhelp.org/posts/Gastroenterology/dilated-Common-bile-duct/show/636657

See your GP if you have the symptoms of bile duct cancer (see below). ... Cancer of the bile ducts, (small tubes that connect the liver, gall bladder and small intestine) is also known as ... Outlook for bile duct cancer. The outlook for bile duct cancer depends on which part of the bile duct is affected and how far ... Symptoms of bile duct cancer. There arent usually any symptoms of bile duct cancer until it grows large enough to block the ...

https://www.nidirect.gov.uk/conditions/bile-duct-cancer

Now, scientists reveal bacteria in the bile duct may also be linked to cancer. ... Bile duct cancer, or cholangiocarcinoma, is cancer that starts in the bile duct, a series of thin tubes that transports bile ... Smoking gun for role of bacteria in bile duct cancer. For their study, Dr. Nagarajan and colleagues profiled the bile duct ... American Cancer Society Bile Duct (Cholangiocarcinoma) Cancer, and What are the key statistics about bile duct cancer?, ...

https://www.medicalnewstoday.com/articles/311237.php

Bile duct tumors cause bile duct obstruction with biliary stasis and a consequent alteration of liver function test results. ... encoded search term (Bile Duct Tumors) and Bile Duct Tumors What to Read Next on Medscape ... which descends for about 2.5 cm before being joined by the cystic duct to form the common bile duct (CBD). The CHD lies to the ... the most important primary tumors of the bile ducts, may involve either the intrahepatic or the extrahepatic biliary ducts. The ...

https://emedicine.medscape.com/article/189843-overview

Mark R Borgaonkar, "Melanoma Extracted from the Common Bile Duct," Canadian Journal of Gastroenterology, vol. 26, no. 7, pp. ... Melanoma Extracted from the Common Bile Duct. Mark R Borgaonkar Memorial University of Newfoundland, St Johns, Newfoundland ...

https://www.hindawi.com/journals/cjgh/2012/269297/cta/

Grading is a way of classifying extrahepatic bile duct cancer cells based on their appearance and behaviour when viewed under a ... To find out the grade of bile duct cancer, the pathologist looks at a tissue sample from the bile duct under a microscope. The ... Grading bile duct cancer. The grade is a description of how the cancer cells look and act compared to normal cells. ... pathologist gives bile duct cancer a grade from 1 to 4. A lower number means the cancer is a lower grade. ...

https://www.cancer.ca/en/cancer-information/cancer-type/bile-duct/grading/?region=sk

Furthermore, an x-ray localization system is essential to visualize the stones after having filled the bile duct over a ... well-controlled shockwaves can be generateJ without the risks for duct perfo ration (as described for the electrohydraulic ... of all common bile duct concrements can be removed via the endoscopic retrograde route via endoscopic sphincterotomy, stone ... Endoscopic Management of Difficult Bile Duct Stones,. Canadian Journal of Gastroenterology and Hepatology,. vol. 6. ,. Article ...

https://www.hindawi.com/journals/cjgh/1992/175814/

... which carry bile to the small intestine for digestion and waste removal. If you have a bile duct obstruction, it can be caused ... Types of bile ducts. You have several types of bile ducts. The two types of bile ducts in the liver are intrahepatic and ... also called bile duct stones or gallstones in the bile duct) is the presence of a gallstone in the common bile duct. ... The biliary duct, or the duct from the gallbladder, also opens into the common hepatic duct. The bile duct from this point ...

https://www.healthline.com/health/bile-duct-obstruction

... what is the common measurement of the bile duct? thanks ... a mild bile duct dilation is consider all right or is a serious ... bile duct dilation goodhealth2008 a mild bile duct dilation is consider all right or is a serious condition, will the liver ... what is the common measurement of the bile duct? thanks ... Create an account to receive updates on: bile duct dilation ...

https://www.medhelp.org/posts/Occupational-Safety--Health/bile-duct-dilation/show/508263

Liver and Intrahepatic Bile Duct Cancer, United States-2006-2015. USCS data brief, no 5. Atlanta, GA: Centers for Disease ... Liver and Intrahepatic Bile Duct Cancer, United States-2006-2015. *Cancers Associated with Human Papillomavirus, United States- ... From 2006 to 2015, the incidence rate for liver and intrahepatic bile duct cancer increased by 32%, and the mortality rate ... In 2015, 32,908 new liver and intrahepatic bile duct cancer cases and 25,760 deaths were reported in the United States. ...

https://www.cdc.gov/cancer/uscs/about/data-briefs/no5-liver-intrahepatic-bile-duct-2016-2015.htm

This glossary can help you to easily understand medical terms related to the article on Bile Duct Cancer ... Infographics on Bile Duct Cancer. Bile duct cancer occurs either within the liver or the point where the bile ducts emerge from ... Test Your Knowledge on Bile Duct Cancer. Bile duct carcinoma (cholangiocarcinoma) is a cancer of the bile ducts, the tubes that ... Aspirin Could Prevent Bile Duct Cancer. *BAP1 Protein Linked to Tumor Suppression in Kidney, Eye, Bile Duct and Mesothelioma ...

https://www.medindia.net/patients/patientinfo/bile-duct-cancer-glossary.htm

... bile duct carinoma, bile duct injury, bile duct stricture, bile leak, biliary colic, biliary disease, biliary tract, bilirubin ... Video Tag: Bile Duct Carinoma. SAGES Webinar : Preparing for the ABSITE-December 2016. ... common bile duct, computed tomography, congenital hemolytic anemia, constipation, continence, COPD, corticosteroids, Crohns ...

https://www.sages.org/video-tag/bile-duct-carinoma/

The bile duct is near the liver and pancreas. So many hepatic and pancreatic diseases also affect the bile duct. The bile duct ... The bile duct is the part of the biliary system transporting bile from the intrahepatic biliary canaliculi in the liver and ... Management of diseases of the bile duct requires a multi-disciplinary team which includes primary care physicians, ... not only anatomical and physiological aspects but also the current diagnostic and therapeutic aspects of different bile duct ...

https://www.intechopen.com/welcome/214bdd1b3b1867823b5af2cbc89aef19

Complete Stenosis of Common Bile Duct: Operative Cure Br Med J 1941; 2 :229 ... Complete Stenosis of Common Bile Duct: Operative Cure. Br Med J 1941; 2 doi: https://doi.org/10.1136/bmj.2.4206.229 (Published ...

http://www.bmj.com/content/2/4206/229.1

Cholangiocarcinoma (bile duct cancer) usually develops in the bile duct system that arises from the liver and bile ducts and ends at the small intestine. (news-medical.net)
Cancer that develops in the section of bile ducts within and outside the liver is called as intrahepatic and hilar cholangiocarcinoma, respectively. (news-medical.net)
Distal cholangiocarcinoma is developed in the bile section that is associated with small intestine. (news-medical.net)
The prognosis of bile duct cancer is affected by various factors such as the site of cancer, type and grade (extent of cell abnormalities when examined under a microscope) of cholangiocarcinoma, physical health condition, treatment, etc. (news-medical.net)
Nevertheless, the prognosis of distal cholangiocarcinoma is better when compared to other two types of bile duct cancer. (news-medical.net)
After extrahepatic cholangiocarcinoma segmentectomy, various data are subjected to evaluation to find the prognostic factors after segmentectomy of extrahepatic bile duct cancer. (news-medical.net)
Cancer of the bile ducts, (small tubes that connect the liver, gall bladder and small intestine) is also known as cholangiocarcinoma. (nidirect.gov.uk)
Bile duct cancer, or cholangiocarcinoma, is cancer that starts in the bile duct, a series of thin tubes that transports bile from the liver and gallbladder to the small intestine to help digest fats in food. (medicalnewstoday.com)
Bile duct carcinoma (cholangiocarcinoma) is a cancer of the bile ducts, the tubes that connect the liver and gall bladder to the small intestine. (medindia.net)
There are several types of cholangiocarcinoma, or bile duct cancer. (moffitt.org)
Cholangiocarcinoma can develop anywhere within the bile duct system, and the condition is classified based on its site of origin. (moffitt.org)
Bile duct cancer is also called cholangiocarcinoma. (aacr.org)
Other names/types of bile duct cancer: cancer of the bile duct, cholangiocarcinoma, intrahepatic bile duct cancer, distal bile duct cancer, extrahepatic bile duct cancer, perihilar bile duct cancer, Klatskin tumour. (bccancer.bc.ca)
Cholangiocarcinoma is a rare form of cancer that forms in bile ducts, which are slender tubes that carry the digestive fluid bile from the liver to gallbladder and small intestine. (fda.gov)
Extrahepatic jaundice is most often due to a stone in the common bile duct (CBD) or a pancreaticobiliary malignancy (pancreatic, ampullary or cholangiocarcinoma). (thefreedictionary.com)
Fortunes turn for Mr. Manzarek, as he passes away from cholangiocarcinoma , bile duct cancer , a rare cancer that afflicts less than 4,000 people a year in the U.S. (medicinenet.com)
Intrahepatic cholangiocarcinoma (ICC) is a rare cancer of the bile ducts in the liver, with limited treatment options and a poor prognosis. (massgeneral.org)
Perihilar bile duct cancer is also called a Klatskin tumor or perihilar cholangiocarcinoma. (oncolink.org)
What are the staging classifications for perihilar bile duct tumors in cholangiocarcinoma (CCC)? (medscape.com)
Strictures of the bile duct may be due to tumors, such as cholangiocarcinoma, gallbladder adenocarcinoma or pancreatic adenocarcinoma, or metastatic disease. (reference.com)
NEW YORK (GenomeWeb) - QED Therapeutics said today that it has partnered with Foundation Medicine to develop a companion diagnostic for its drug candidate infigratinib in patients with cholangiocarcinoma (bile duct cancer). (genomeweb.com)
Bile duct cancer (cholangiocarcinoma) is a cancer of the biliary duct system, which includes the gallbladder, bile ducts, and certain cells inside the liver. (va.gov)
Cholangiocarcinoma, or bile duct cancer, occurs when a malignant (cancerous) tumor grows in one of the ducts that transport bile from the liver to the small intestine. (hopkinsmedicine.org)
Cholangiocarcinoma, also called bile duct cancer, occurs when a cancerous tumor grows in the bile ducts. (hopkinsmedicine.org)
Bile duct cancer is also referred to as cholangiocarcinoma. (hoag.org)
Norton Cancer Institute, the leading provider of cancer care in Louisville and Southern Indiana, offers same-day appointments for patients newly diagnosed with cholangiocarcinoma, also known as bile duct cancer. (nortonhealthcare.com)
The determination that plasma IL-6 levels are associated with bile duct fibrosis (a precursor state to bile duct cancer) and early bile duct cancer were done by examining participants in the Khon Kaen Cholangiocarcinoma Cohort, the largest cancer cohort of its type in the world, and an NIH sponsored project in collaboration with George Washington University and Khon Kaen University. (innovations-report.com)
Each year, about six million northeastern people are diagnosed with bile duct cancer, or cholangiocarcinoma, the highest number in the world. (pattayamail.com)
Cholangiocarcinoma is cancer of the bile ducts. (bostonscientific.com)
For more information on Bile Duct Cancer, including the latest research, patient and caregiver support, visit the Cholangiocarcinoma Foundation . (bostonscientific.com)

Tubes that carry bile from your liver to your gallbladder for storage and to the duodenum (the first part of your small intestine) for use in digestion. (nih.gov)
They carry the bile to your small intestine. (medlineplus.gov)
Bile is carried from the liver to the gallbladder and then from the gallbladder to the small intestine. (news-medical.net)
Bile ducts are small tubes that connect the liver, gall bladder and small intestine. (nidirect.gov.uk)
The bile ducts carry bile from the liver and gallbladder through the pancreas to the duodenum, which is a part of the small intestine. (healthline.com)
Before emptying into the small intestine, the common bile duct passes through the pancreas. (healthline.com)
The bile duct is a thin tube that spans from the liver to the first part of the small intestine (duodenum). (moffitt.org)
The bile ducts are thin tube-like vessels that carry bile from the liver to the gallbladder and small intestine. (aacr.org)
The bile duct is a 4-5 inch long tube that carries bile from the liver to the gallbladder and then to the small intestine. (bccancer.bc.ca)
Bile is a fluid made in the liver to help digest fats in the small intestine. (bccancer.bc.ca)
Bile is sent to the gallbladder where it is stored until it is needed in the small intestine to help digest food. (bccancer.bc.ca)
Bile duct obstruction is a blockage in the tubes that carry bile from the liver to the gallbladder and small intestine. (patientslikeme.com)
They carry a thick fluid called bile, from the liver to the upper part of the small intestine (duodenum) to aid in digesting food. (mdanderson.org)
This disease arises near the small intestine, at the farthest reach of the bile ducts. (mdanderson.org)
When food is being digested, bile stored in the gallbladder is released and passes through the cystic duct to the common bile duct and into the small intestine. (oncolink.org)
The distal region is made up of the common bile duct which passes through the pancreas and ends in the small intestine. (oncolink.org)
Once food has been ingested, bile is released into the small intestine to aid in the digestion and break down of food so that it can be used appropriately by the body or carried out as waste. (petmd.com)
This region includes the common bile duct and inserts into the small intestine. (oncolink.org)
The function of the common bile duct is to carry bile from the liver and the gallbladder into the duodenum, the top of the small intestine directly after t. (reference.com)
The bile ducts are small channels within the gallbladder and liver that secrete bile into the duodenum (small intestine) to aid in digestion. (virginiamason.org)
Disorders of the bile duct oftentimes have the same symptoms because most of them block the ducts from releasing bile or digestive enzymes into the small intestine. (virginiamason.org)
A tube that carries bile from the liver and the gallbladder through the pancreas and into the duodenum (the upper part of the small intestine). (cancer.gov)
The bile duct is part of a network of tubes that connect the liver, gallbladder, pancreas, and small intestine. (utah.edu)
Bile duct begins in the liver and ends in the small intestine. (altiusdirectory.com)
Bile duct cancer starts in the bile ducts, which are thin tubes between the liver and the small intestine. (cancertutor.com)
The ducts move bile (a greenish-brown alkaline fluid that aids digestion) from the liver and gallbladder to the small intestine, where it helps digest the fats in food. (cancertutor.com)
A bile duct is a tube that carries bile (fluid made by the liver) between the liver and gallbladder and then on to the small intestine. (umc.edu)
Bile is released by the gallbladder into the small intestine to help break down fats. (nortonhealthcare.com)
Bile is a digestive fluid secreted by the liver and stored in the gallbladder which normally is released into the duodenum portion of the small intestine through the sphincter of Oddi. (mountsinai.org)
Whipple Procedure: A surgical procedure in which the head of the pancreas, the gallbladder, part of the stomach, part of the small intestine and the bile duct are removed. (cancersupportcommunity.org)
Surgical Biliary Bypass: This is done if the tumor cannot be removed but is blocking the small intestine and causing bile to build up in the gallbladder. (cancersupportcommunity.org)

Most patients with bile duct tumors present with jaundice due to obstruction of the biliary tree by the tumor. (medscape.com)
The anticipated course of most cases of bile duct tumors includes recurrent biliary obstruction with infectious complications, local spread, and death in 6-12 months. (medscape.com)
A biliary obstruction is a blockage of the bile ducts . (healthline.com)
Obstruction of any of these bile ducts is referred to as a biliary obstruction. (healthline.com)
Data from patients with bile duct obstruction, who reported starting treatments within the last 5 years. (patientslikeme.com)
In malignant bile duct obstruction , these interventions are used for palliation of symptoms including anorexia and pruritus as well as to reduce the serum bilirubin levels to allow administration of chemotherapy. (thefreedictionary.com)
PDA typically presents as an infiltrative hypovascular solid mass, frequently associated with pancreatic and/or common bile duct obstruction and local vascular invasion (2). (thefreedictionary.com)
Duodenal diverticulum is not rare, but complications like perforation, bleeding, pancreatitis, and bile duct obstruction are very rare. (thefreedictionary.com)
Baron, "Meta-analysis of randomized trials comparing the patency of covered and uncovered self-expandable metal stents for palliation of distal malignant bile duct obstruction ," Gastrointestinal Endoscopy, vol. (thefreedictionary.com)
Facts and fallacies of common bile duct obstruction by pancreatic pseudocysts. (thefreedictionary.com)
Stones in the common bile duct can cause biliary obstruction, cholangitis, pancreatitis, or secondary biliary cirrhosis in patients who have had the stones for a long time. (cmaj.ca)
An obstruction of the bile duct, also called cholestasis, is a term used to describe what happens when the bile duct is blocked and prevents bile from entering the intestine. (petmd.com)
Symptoms relating to bile duct obstruction in cats can include l ethargy, lack of appetite or excessive hunger (also called polyphagia ), vomiting, jaundice , weight loss, dark urine, jaundice (discoloration of the skin or eyes) and pale colored stool. (petmd.com)
Your veterinarian will require you to give them a complete history of your cat's health, including a clear description of your cat's symptoms and anything that may have preceded the condition that can be causing the bile duct obstruction, such as an injury to the body, a prior surgery or gallstones. (petmd.com)
The amount of waste product found in your cat's blood will also be indicative of a problem, including high levels of bilirubin , a component of bile and blood fluids that usualy leaves the body as waste but may remain in the blood as a result of the bile duct obstruction. (petmd.com)
The physician may also insert small tubes (called stents) into the bile duct or the pancreatic duct, if they are obstructed, to relieve the obstruction. (hoag.org)
The most common cause of common biliary duct dilatation is obstruction due to gallstones, states the Radiology Assistant. (reference.com)
Another cause of obstruction besides gallstones is stricture, or narrowing, of the common bile duct. (reference.com)
If there are no gallstones and no strictures causing obstruction, the cause of the bile duct dilatation may be non-obstructive biliary disease, notes the Radiology Assistant. (reference.com)
I was admitted to the hospital last night and found out I have a bile duct obstruction. (cancer.org)
In Group 2, 10 dogs underwent transient common bile duct obstruction. (scielo.br)
Common bile duct obstruction secondary to infection with Candida. (asm.org)
A patient is reported who had biliary tract obstruction secondary to infection of the common bile duct with Candida albicans, with the formation of a fungus ball. (asm.org)
Ureteral obstruction through fungus ball formation, and even pulmonary fungus ball formation, has been attributed to candida, but this is the first case reported, to our knowledge, of bile duct obstruction. (asm.org)

This joins the cystic duct , which leads from the gall bladder , to form the common bile duct , which drains into the duodenum. (encyclopedia.com)
15 mm in diameter) bile duct stones, intrahepatic stones, or impacted stones in the bile duct or cystic duct. (nih.gov)
The majority of bile duct stones are secondary bile duct stones (Chap. 3 ) that arise in the gallbladder and migrate down the cystic duct. (springer.com)
The main right and left hepatic ducts from the liver unite near the right end of the porta hepatis to form the common hepatic duct (CHD), which descends for about 2.5 cm before being joined by the cystic duct to form the common bile duct (CBD). (medscape.com)
The hepatic ducts and the upper and middle portions of the CBD are supplied with blood primarily by rami from the cystic artery. (medscape.com)
Any of the excretory passages in the liver that carry bile to the hepatic duct, which joins with the cystic duct to form the common bile duct opening into the duodenum. (thefreedictionary.com)
The duct formed by the union of the cystic duct and the hepatic duct that carries bile from the liver and the gallbladder to the duodenum. (thefreedictionary.com)
Stones in the common bile duct most commonly result from the passage of gallstones through the cystic duct into the common bile duct. (cmaj.ca)
The cystic duct connects the gallbladder to the common hepatic duct. (oncolink.org)
Bile from the liver passes through the hepatic ducts, common hepatic duct, and cystic duct and is stored in the gallbladder. (oncolink.org)
Bile is made in the liver and flows through the common hepatic duct and the cystic duct to the gallbladder, where it is stored. (oncolink.org)
The hilum is the region where the right and left hepatic ducts exit the liver and join to form the common hepatic duct that is proximal to the origin of the cystic duct. (oncolink.org)
Bile ducts include the common hepatic, cystic and common bile ducts. (uvahealth.com)
Symptoms may develop suddenly, as when a gallstone blocks the cystic duct within the gallbladder, or may occur over several years as scar tissue develops. (virginiamason.org)
2. any of the ducts conveying bile between the liver and the intestine, including hepatic, cystic, and common bile ducts. (thefreedictionary.com)
A generic term for any of the ducts which begin with the bile canaliculi in the liver, converging in turn with the canals of Hering, the interlobular bile ducts, intrahepatic bile ducts, and the left and right hepatic ducts to become the common hepatic duct, which exits the liver and joins the cystic duct forming the common bile duct. (thefreedictionary.com)
The common hepatic duct and the cystic duct are regarded as the "bile ducts", which then enter the pancreas, merge with pancreatic duct, dilate to form the ampulla of Vater, pass through the sphincter of Oddi and enter the duodenum. (thefreedictionary.com)
Any of the intercellular passages that convey bile from the liver to the hepatic duct, which joins the duct from the gallbladder (cystic duct) to form the common bile duct (ductus choledochus), and which enters the duodenum about 3 in (7.6 cm) below the pylorus. (thefreedictionary.com)
Just under the liver, this gives off a branch, the cystic duct, to the gall bladder. (thefreedictionary.com)
2. specifically the terminal segment of the biliary tree extending from the union of the common hepatic duct and cystic duct to the major duodenal papilla. (thefreedictionary.com)

An international group of researchers has found a link between gut bacteria in the bile duct and a raised risk of developing bile duct cancer. (medicalnewstoday.com)
This study by Lewis Roberts and colleagues showed that people who took aspirin had 3.5 times lower risk of developing bile duct cancer. (medindia.net)
The main risk factor for developing bile duct cancer in the northeast of Thailand is eating raw freshwater fish, leading to an infection of liver flukes in the bile duct. (bumrungrad.com)

Tumors of the bile duct constitute about 2% of all cancers found at autopsy. (medscape.com)
Cholangiocarcinomas, the most important primary tumors of the bile ducts, may involve either the intrahepatic or the extrahepatic biliary ducts. (medscape.com)
These tumors account for 40 to 60% of all bile duct cancer cases. (mdanderson.org)
TNM staging for perihilar bile duct tumors. (medscape.com)
Tumors of the Bile Ducts, Gallbladder, and Ampulla. (medscape.com)
Traditionally, bile duct tumors located within the liver had been classified with hepatocellular carcinoma as primary liver tumors. (oncolink.org)
In contrast, bile duct tumors located outside of the liver had been classified with gallbladder cancer as extrahepatic biliary tract tumors. (oncolink.org)
The classification of bile duct tumors has changed to include intrahepatic tumors of the bile ducts and extrahepatic tumors (perihilar and distal) of the bile ducts. (oncolink.org)
Tumors of the intrahepatic bile ducts originate in small intrahepatic ductules or large intrahepatic ducts that are proximal to the bifurcation of the right and left hepatic ducts. (oncolink.org)
Bile duct tumors are usually slow growing and treatment often depends on the location of the tumor. (hopkinsmedicine.org)
The distinction between the two types of tumors is important since bile duct cancer treatment is based on the tumor location. (hoag.org)

In this method, a sequence of images of interior body parts such as bile duct, pancreas, liver, gall bladder, and pancreatic duct are generated by making use of radio waves, a magnet, and a computer. (news-medical.net)
Malignant strictures are usually the result of either a primary bile duct cancer (ie, causing a narrowing of the bile duct lumen and obstructing the flow of bile) or extrinsic compression of the bile ducts by a neoplasm in an adjacent organ, such as the gallbladder, pancreas, or liver (see image below). (medscape.com)
They allow fluid called bile to flow from the liver, through the pancreas, to the gut, where it helps with digestion. (nidirect.gov.uk)
An MRI scan provides detailed pictures of the liver, gallbladder, pancreas, and bile ducts. (healthline.com)
The bile duct is near the liver and pancreas. (intechopen.com)
Islets were isolated using a liberase enzyme prepared in HBSS buffer which was injected into the common bile duct to distend the pancreas. (thefreedictionary.com)
Bile can't travel though the blocked bile duct and it backs up, causing inflammation of the liver and pancreas. (medicinenet.com)
Endoscopic Ultrasound (EUS) uses an ultrasound device to make images of your bile duct and pancreas from inside your abdomen. (hoag.org)
Endoscopic Retrograde Cholangiopancreatography (ERCP) uses a dye to highlight the bile ducts in the pancreas, so that an accurate image of the bile duct and pancreatic duct may be obtained. (hoag.org)
Surgery of the Liver, Bile Ducts and Pancreas in Children, Third Edition describes the modern approach to the diagnosis, management and surgery of childhood conditions of the liver and associated structures. (routledge.com)
Parasitic disease of Liver, Bile ducts and Pancreas. (routledge.com)
The pancreas also secretes digestive enzymes into the duodenum through the pancreatic duct. (virginiamason.org)
Magnetic resonance cholangiopancreatography (MRCP) is performed in Radiology using MRI technology (magnets and radio waves) to produce computer images of the gallbladder, pancreas and bile ducts. (virginiamason.org)
Endoscopic retrograde cholangiopancreatography, or ERCP, is a specialized endoscopic technique used to study the gallbladder, pancreas and bile ducts, and has the added benefit of being a therapeutic tool. (virginiamason.org)
A tumor that completely blocks a bile duct can lead to inflammation of organs within the biliary tract (gallbladder, liver and pancreas) as well as a serious bacterial infection within the liver (ascending cholangitis). (virginiamason.org)
UW Health Liver and Pancreas Surgeons in Madison, Wisconsin are experts in the surgical management of bile duct disorders. (uwhealth.org)

No matter where they are, nearly all bile duct cancers start in the innermost layer of the wall of the bile duct (called the mucosa ). (cancer.org)
The earliest stage intrahepatic bile duct cancers are stage 0 (also called carcinoma in situ, or CIS) . (cancer.org)
While their role in the development of colon and gastrointestinal cancers is now better understood, this cannot be said of the involvement of bacteria in the development of bile duct cancer, note the authors. (medicalnewstoday.com)
Thus, the 5-year survival prognosis is much less optimistic than for many cancers, ranging from 5-30 percent, depending on the type of bile duct cancer. (medicalnewstoday.com)
Most bile duct cancers are adenocarcinomas that start in the glandular cells lining the inside of the duct. (moffitt.org)
Bile duct cancer and ampullary cancer risk were also lowered with the use of aspirin, however, the number of patients with these types of cancers was low. (medindia.net)
Though prolonged use of aspirin has shown a reduction in gallbladder cancer and bile duct cancer risk, it cannot be used as a preventive medication for these cancers right away as further research is required to support these studies. (medindia.net)
Mayo Clinic Q&A podcast: Hidden gallbladder and bile duct cancers Feb. 22, 2021, 05:30 p.m. (mayoclinic.org)
For bile duct cancers, quantity (how long people live and how long they can survive), depends upon exactly where in the bile duct the cancer is located. (medicinenet.com)
Bile duct cancers hide deep within the abdomen, hidden by the bulk of the liver, and are largely unable to be detected. (medicinenet.com)
Can understanding the genetic mechanisms driving resistance to the FGFR inhibitor BGJ398 lead to better therapies for bile duct and other cancers? (massgeneral.org)
Listen to Dr. Lipika Goyal discuss her research of the genetic mechanisms that drive resistance and that may lead to better therapies for bile duct and other cancers. (massgeneral.org)
If the findings can be repeated in a larger population, they could guide the development of more durable therapeutic strategies for bile duct cancer, as well as for the wide variety of other cancers that are driven by alterations in the FGFR pathway in a subset of patients. (massgeneral.org)
Cancers of the bile ducts are relatively uncommon in the United States. (mdanderson.org)
Since most bile duct cancers are diagnosed in more advanced stages, the current five-year survival rate is only 10% to 30%, depending upon the type of cancer. (mdanderson.org)
In the U.S., Native Americans and Hispanics are more likely to get bile duct cancers. (mdanderson.org)
Only a small number of bile duct cancers are intrahepatic . (oncolink.org)
Intrahepatic bile duct cancers are also called intrahepatic cholangiocarcinomas. (oncolink.org)
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of bile duct cancers. (oncolink.org)
Many bile duct cancers are multifocal. (oncolink.org)
Nearly all bile duct cancers are called cholangiocarcinomas (composed of mutated epithelial cells). (cancertutor.com)
Researchers do not know the exact cause of most bile duct cancers. (cancertutor.com)
However, there seems to be a link between these cancers and things that irritate and inflame the bile ducts - bile duct stones, choledochal cysts, parasites, cirrhosis of the liver, or something else. (cancertutor.com)
There is no known way to prevent most bile duct cancers. (cancertutor.com)
Many of the known risk factors for bile duct cancers, such as age, ethnicity, and bile duct abnormalities, are beyond our control. (cancertutor.com)
At Sutter Delta Medical Center, doctors are skilled at treating liver and bile duct cancers using a variety of diagnostic tests, surgical procedures, drug therapies and radiation therapies. (sutterhealth.org)
For some cancers, we offer a variety of advanced surgical techniques , including embolization therapy, bile duct resection, biliary bypass surgery and liver resection. (sutterhealth.org)
HOUSTON - Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. (eurekalert.org)

Virginia Mason is an international center for treating patients with biliary tract disorders, including cancer of the bile ducts. (virginiamason.org)

Tests to diagnose bile duct cancer may include a physical exam, imaging tests of the liver and bile ducts, blood tests, and a biopsy. (medlineplus.gov)
Several tests may be needed to help diagnose bile duct cancer. (nidirect.gov.uk)
Different procedures may be used to obtain a sample of tissue and diagnose bile duct cancer. (oncolink.org)
Procedures that make pictures of the bile ducts and the nearby area help diagnose bile duct cancer and show how far the cancer has spread. (cancer.gov)
Your health care provider uses medical history, physical examination, and may employ a variety of blood tests and medical imaging (Xrays, CT, MRI scans, and/or ultrasound) and consultation with specialists to diagnose bile duct cancer. (va.gov)

If a tumor grows through the bile duct wall, it can invade (grow into) nearby blood vessels, organs, or other structures. (cancer.org)
T describes whether the main (primary) tumor has invaded through the wall of the bile duct and whether it has invaded other nearby organs or tissues. (cancer.org)
Some of the risk factors that affect the prognosis of distal bile duct cancer are perineural infiltration, tumor markers, tumor cell differentiation, serum bilirubin, lymph node metastasis, amount of transfusion, age, etc. (news-medical.net)
Most of these patients die of complications of tumor invasion and metastasis rather than from the bile duct stricture per se. (medscape.com)
The researchers profiled the microbiomes of fluke-associated (Ova) versus non-associated (non-Ova) tumor (T) and normal (N) bile duct tissues, and found differences in relative proportions of bacteria species. (medicalnewstoday.com)
During PDT, a doctor gives an inactive form of a drug and then directs a special light at the tumor in the bile duct, using an endoscope in a procedure similar to ERCP. (cancer.net)
Surgery, however, may be performed to remove a portion of the tumor and reroute the bile duct to allow better drainage of bile. (virginiamason.org)
The cancer that starts in the junction of the bile ducts is called Klatskin's Tumor. (altiusdirectory.com)
Starting with clinical symptoms, diagnosis of bile duct cancer involves biochemical tests like liver function tests, tumor marker tests, biopsy, ultrasound, CT scan, MRI scan and endoscopic examination. (altiusdirectory.com)
Cancer is an uncontrolled growth of abnormal cells (a malignant tumor) that can begin in the cells of the liver, bile duct, or surrounding organs. (umc.edu)
Removal of the Bile Duct: If the tumor is small and only in the bile duct, the entire bile duct may be removed. (cancersupportcommunity.org)
If during the surgery to remove the tumor, the surgeons discover that the cancer has spread to such an extent that it cannot be removed, the surgeons will provide palliative therapy by draining bile to relieve the patient's itchy skin and jaundice (yellowing of the skin and eyes). (bumrungrad.com)

Difficult bile duct stones. (nih.gov)
Bile duct stones are routinely removed at time of endoscopic retrograde cholangiopancreatography (ERCP) after biliary sphincterotomy with standard balloon or basket extraction techniques. (nih.gov)
Follow-up ERCP attempts to remove the difficult bile duct stones may be performed locally if expertise is available or alternatively referred to a tertiary center for advanced extracorporeal or intracorporeal fragmentation (mother-baby laser or electrohydraulic lithotripsy) techniques. (nih.gov)
Nearly all patients with bile duct stones can be treated endoscopically if advanced techniques are utilized. (nih.gov)
A thoughtful approach to each patient with difficult bile duct stones and a healthy awareness of the operator/endoscopy unit limitations is necessary to ensure the best patient outcomes. (nih.gov)
Dias MM, Martin CJ, Cox MR. Patterns of management of common bile duct stones in the laparoscopic era: a NSW survey. (springer.com)
Treatment of Common Bile Duct Stones in Sweden 1989-2006: an Observational Nationwide Study of a Paradigm Shift. (springer.com)
Blind PJ, Lundmark M. Management of bile duct stones: lithotripsy by laser, electrohydraulic, and ultrasonic techniques. (springer.com)
Randomized trial of laparoscopic exploration of common bile duct versus postoperative endoscopic retrograde cholangiography for common bile duct stones. (springer.com)
Furthermore, an x-ray localization system is essential to visualize the stones after having filled the bile duct over a nasobiliary catheter. (hindawi.com)
There was no correlation between the use of aspirin and bile stones. (medindia.net)
Some diseases, such as polycystic liver disease, ulcerative colitis, stones in the bile duct, choledochal cysts, cirrhosis (damage to the liver) and Caroli syndrome, may increase the risk of bile duct cancer. (bccancer.bc.ca)
The presence of stones in the common bile duct affects more than 61 million people worldwide, resulting in 800,000 therapeutic ERCP procedures each year. (thefreedictionary.com)
4 - 7 One complication is the occurrence of stones in the common bile duct. (cmaj.ca)
More than 1 in 10 patients (10%-18%) undergoing cholecystectomy for gallstones have concomitant common bile duct stones, 7 and up to 3.8% have symptoms related to common bile duct stones during the first year after cholecystectomy. (cmaj.ca)
The management of patients with gallstone disease suspected of having stones in the common bile duct has three aims: to evaluate the probability of stones in the common bile duct, to treat these stones when present, and to treat the stones in the gallbladder. (cmaj.ca)
When should common bile duct stones be suspected? (cmaj.ca)
Symptoms and signs suggestive of common bile duct stones can occur in people with intact gallbladders as well as those who have had a cholecystectomy. (cmaj.ca)
Ducts can become blocked with stones, form strictures or scar tissue, or become narrowed from infection, inflammation or cancer. (virginiamason.org)
Endoscopic balloon sphincter dilation (sphincteroplasty) versus sphincterotomy for common bile duct stones. (uptodate.com)
OBJECTIVES: To assess the beneficial and harmful effects of endoscopic balloon dilation versus endoscopic sphincterotomy in the management of common bile duct stones. (uptodate.com)
SELECTION CRITERIA: Randomised clinical trials comparing endoscopic balloon dilation versus endoscopic sphincterotomy in removal of common bile duct stones irrespective of publication status, language, or blinding. (uptodate.com)
BACKGROUND: Balloon dilation or sphincteroplasty is emerging as a potentially safe and effective alternative to sphincterotomy in the management of bile duct stones. (uptodate.com)
when unnatural foods are run through the body, and an unnatural lifestyle is carried on, bile changes in it's chemical make up, consistency and liquidity, often causing it to dehydrate, stagnate and clump up into stones. (curezone.com)
Association between common bile duct stones and treated hypothyroidism. (wellnessresources.com)
The purpose of this study was to investigate the frequency of diagnosed hypothyroidism in patients with common bile duct stones. (wellnessresources.com)
These patients did not have diagnosed gallbladder or common duct stones. (wellnessresources.com)
In addition, we studied 36 consecutive gallbladder stone patients (Group III) of over 60 years, who had no evidence of common bile duct stones. (wellnessresources.com)
There is a significant association between the common bile duct stones and previously diagnosed hypothyroidism. (wellnessresources.com)
There stronger association between the common bile duct stones and hypothyroidism compared to gallbladder stones and hypothyroidism suggests a mechanism other than merely the cholesterol metabolism mediated mechanism. (wellnessresources.com)
The 11% prevalence of previously diagnosed hypothyroidism in the common bile duct stone patients of over 60 years of age suggests all patients with common bile duct stones be screened for current thyroid dysfunction. (wellnessresources.com)

Many small ducts drain into the right and left hepatic ducts, which unite to form the main bile duct, the common hepatic duct . (encyclopedia.com)
They can be divided into: Lobar ducts (right and left hepatic ducts) - stratified columnar epithelium. (wikipedia.org)
Most strictures after a laparoscopic procedure are short and occur more commonly in the common hepatic duct (ie, distal to the confluence of the right and left hepatic ducts). (medscape.com)
The small ducts come together to form the right and left hepatic ducts, which lead out of the liver. (oncolink.org)
They include part of the right and left hepatic ducts that are outside the liver, the common hepatic duct, and the common bile duct. (oncolink.org)

The risk factors for bile duct cancer include primary sclerosing cholangitis (a gradually developing disorder in which inflammation and scarring block bile ducts), chronic ulcerative colitis, and cysts within the bile ducts (these block bile flow, leading to bile duct enlargement, infection, and inflammation). (news-medical.net)
The risk of developing the cancer is linked to presence of cysts and inflammations that block the bile duct. (medicalnewstoday.com)
Cysts in the bile ducts (cysts block the flow of bile and can cause swollen bile ducts, inflammation, and infection ). (oncolink.org)
Cholestasis is associated with a number of diseases, including gallstones , pancreatitis , a parasitic infestation, liver inflammation ( cholangitis ), cysts in the liver and bile duct or as a side effect of abdominal surgery. (petmd.com)
Bile duct cancer may occur more frequently in patients with a history of primary sclerosing cholangitis, chronic ulcerative colitis, choledochal cysts, or infections with the liver fluke Clonorchis sinensis. (oncolink.org)
It is a rare form of cancer that can be triggered by underlying conditions such as chronic liver inflammation, ulcerative colitis and cysts in the bile duct . (altiusdirectory.com)

This is a surgical procedure to examine the interior portion of the abdomen such as liver and bile duct to check up for signs and symptoms of cancer. (news-medical.net)
Investigation of the Liver and Bile Ducts. (routledge.com)
Liver and Bile Ducts (Benign). (routledge.com)
Liver and Bile Duct Trauma. (routledge.com)
Getting a picture of your liver and bile ducts can help your doctor determine the best course of treatment for your particular cancer. (sutterhealth.org)
The Biesecker Pediatric Liver Center at The Children's Hospital of Philadelphia is actively involved in research studies on liver and bile duct disease and development. (chop.edu)

See your GP if you have the symptoms of bile duct cancer (see below). (nidirect.gov.uk)
There aren't usually any symptoms of bile duct cancer until it grows large enough to block the bile ducts. (nidirect.gov.uk)
Symptoms of bile duct cancer include jaundice (yellowing of the skin and the whites of the eyes), pain in the abdomen, dark urine, light or 'clay' colored stool, fever, itchy skin, nausea and vomiting, and unexplained weight loss. (va.gov)

Risk factors include having inflammation of the bile duct, ulcerative colitis , and some liver diseases. (medlineplus.gov)
Primary sclerosing cholangitis results in strictures in the bile ducts and is associated with ulcerative colitis and Crohn's disease. (reference.com)

n. the duct that conveys bile from the liver and the gallbladder to the duodenum. (encyclopedia.com)
It opens, in common with the pancreatic duct, into the ampulla of Vater, which is situated in the second part of the duodenum. (medscape.com)
The bile duct is the part of the biliary system transporting bile from the intrahepatic biliary canaliculi in the liver and also from the gallbladder to the duodenum. (intechopen.com)
The intrahepatic biliary tree is responsible for concentrating and transporting bile from the blood stream, while extrahepatic portions store and secretes bile into the duodenum 4 . (nature.com)
The pancreatic duct (of Wirsung) extends through the length of the gland and empties into the duodenum at the hepatopancreatic ampulla (of Vater) through which the common bile duct from the liver and gallbladder also enters the duodenum. (thefreedictionary.com)
The biliary system is comprised of the organs and duct system that create, transport, store and release bile into the duodenum for digestion. (mountsinai.org)
The duct continues down, as the 'common bile duct' to run into the DUODENUM . (thefreedictionary.com)
the duct through which bile passes from the liver or gall bladder to the duodenum. (thefreedictionary.com)

The interlobular bile ducts (or interlobular ductules) carry bile in the liver between the Canals of Hering and the interlobar bile ducts. (wikipedia.org)
Intrahepatic bile ducts are a network of small tubes that carry bile inside the liver. (oncolink.org)
Extrahepatic bile ducts are small tubes that carry bile outside of the liver. (oncolink.org)
The biliary system consists of a network of ducts that carry bile from the liver to the small bowel and is classified by its anatomic location (Figure 1). (oncolink.org)
Bile ducts are long, tube-like structures that carry bile , which is secreted by the liver and is essential for helping us digest food. (fightaging.org)

1990) Left hepatic duct anatomy: implications. (springer.com)
Karakousis CP, Douglass HO (1977) Hilar hepatojejunostomy in resection of carcinoma of the main hepatic duct junction. (springer.com)
Endoscopic retrograde cholangiopancreatographic cholangiogram demonstrating an isolated mid-hepatic duct stricture as a result of pancreatic cancer. (medscape.com)
As they descend from the liver, they unite to form the common hepatic duct. (healthline.com)
The biliary duct, or the duct from the gallbladder, also opens into the common hepatic duct. (healthline.com)
in type II, atresia is at the level of the hepatic duct (2. (thefreedictionary.com)
The two ducts join outside the liver and form the common hepatic duct . (oncolink.org)
This type of cancer is found in the hilum region, the area where the right and left bile ducts exit the liver and join to form the common hepatic duct. (oncolink.org)
They are made up of the common hepatic duct (hilum region) and the common bile duct (distal region). (oncolink.org)
Klatskin G. Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis. (medscape.com)
The bile collecting tubules in the liver join up to form a main tube called the hepatic duct. (thefreedictionary.com)

However, not all bile duct strictures are benign. (medscape.com)
Nonetheless, both benign and malignant bile duct strictures can be associated with distressing symptoms and excessive morbidity. (medscape.com)
Strictures of the bile duct can be benign or malignant. (medscape.com)
Benign strictures develop when the bile ducts are injured in some way. (medscape.com)
Depending on the nature of the insult, bile duct strictures can be single or multiple. (medscape.com)
Atrophy of the hepatic segment or lobe drained by the involved bile ducts, associated with hypertrophy of the unaffected segments, can occur, especially with chronic high-grade strictures. (medscape.com)
The causes of benign bile duct strictures are usually surgical inexperience, failure to recognize abnormal biliary anatomy and congenital anomalies, acute inflammation, misplacement of clips, excessive use of cautery, and excessive dissection around the major bile ducts, resulting in ischemic injury. (medscape.com)
Bile duct strictures can also occur as unexpected complications after other surgeries, such as gastrectomy, pancreatic surgery, or hepatic and portal vein surgery. (medscape.com)
announced the European availability of the WallFlex Biliary RX Stent for the treatment of malignant common bile duct strictures. (thefreedictionary.com)

The common bile duct averages about 10 cm in length, and flow of bile from its lower end into the intestine is controlled by the muscular action of the hepatopancreatic sphincter (sphincter of Oddi), located in the duodenal papilla. (britannica.com)
These ducts tend to be confined and the flow of bile is restricted or slowed down, which leads to jaundice. (news-medical.net)
The cancer in the bile duct blocks the flow of bile, causing a yellowing of the skin and eyes. (bumrungrad.com)

is used to examine the bile duct and pancreatic ducts for the presence of gallstones, tumours, or inflammation. (britannica.com)
Before the major open surgery, she underwent a procedure known as endoscopic stenting, in which a stent was inserted in her bile duct to prevent it from narrowing due to the gallstones before the open surgery. (mid-day.com)
The common bile duct stone group (Group I) consisted of all the patients who had verified gallstones in the common bile duct in endoscopic retrograde cholangiopancreatography during 1995. (wellnessresources.com)

This ERCP method is used to x-ray the ducts (also known as tubes). (news-medical.net)
Heinerman PM, Boeckl O, Pimpl W. Selective ERCP and pre-operative stone removal in bile duct surgery. (springer.com)
Prospective randomized trial of LC + LCBDE vs ERCP/S + LC for common bile duct stone disease. (springer.com)
ERCP - Endoscopic Retrograde Cholangiopancreatography - A tube is passed down the throat and into the bile duct. (bccancer.bc.ca)
MRCP is being used primarily in patients who may have failed or who are not good candidates for ERCP, in those who do not want to undergo an endoscopic procedure, and in individuals considered to be at low risk of having a pancreatic duct or bile duct disorder. (virginiamason.org)
A definitive diagnosis is made through a procedure called ERCP, for endoscopic retrograde cholangiopancreatography, which allows your gastroenterologist to view the biliary and pancreatic ducts. (virginiamason.org)

People with chronic inflammation of the bile duct, called sclerosing cholangitis, have an increased risk of bile duct cancer. (bccancer.bc.ca)

The two types of bile ducts in the liver are intrahepatic and extrahepatic ducts. (healthline.com)
In contrast, large cholangiocytes populate larger diameter intrahepatic and extrahepatic ducts and display a mature cholangiocyte phenotype by being active in bile transport. (nature.com)

it may block the common bile duct, which leads to a buildup of bilirubin in the blood and causes jaundice (a yellowing of the skin and eyes). (britannica.com)
Symptoms of both gallbladder and bile duct cancer include yellowing of the skin and/or the whites of the eyes (jaundice), abdominal pain, and fever. (aacr.org)
The blockage can cause bile to build up in the liver resulting in jaundice (yellow color of the skin) due to the increasing levels of bilirubin in the blood. (patientslikeme.com)
Signs of bile duct cancer include jaundice and pain in the abdomen. (oncolink.org)
Jaundice or abnormal liver enzyme blood tests are the most common reasons physicians would suspect a problem with the bile ducts. (clevelandclinic.org)
As the cancerous growth blocks the bile duct, the first symptoms experienced by the patient include jaundice due to accumulation of bile. (altiusdirectory.com)
When the bile ducts become blocked, bile builds up in the liver, and jaundice (yellow color of the skin) develops due to the increasing level of bilirubin in the blood. (mountsinai.org)

Around 20% to 30 % of the extrahepatic bile duct cancer patients survive for five years after surgical resection. (news-medical.net)
Some patients survive even after five years even though they are affected with recurrent extrahepatic bile duct cancer. (news-medical.net)
Extrahepatic bile duct cancer is a rare disease in which cancer cells form in the ducts that are outside the liver. (aacr.org)
Extrahepatic Bile Duct Cancer Clinical Trials. (medicinenet.com)
Perihilar bile duct cancer is the most common type of extrahepatic bile duct cancer. (mdanderson.org)
The extrahepatic bile duct is made up of the hilum region and the distal region. (oncolink.org)
Anatomy of the extrahepatic bile duct. (oncolink.org)
Having colitis or certain liver diseases can increase the risk of extrahepatic bile duct cancer. (uvahealth.com)
Extrahepatic bile duct cancer starts in the bile duct outside the liver. (bumrungrad.com)

It starts small, in the tube that delivers bile from the liver and gallbladder into the intestine, helping digest fats and getting rid of waste products. (medicinenet.com)
If the cancer begins in the duct after it has left the liver on the way to the intestine, survival is marginally better. (medicinenet.com)
The bile ducts connect the liver to the intestine and their function is to drain the bile, a waste product of normally functioning liver cells, which are also called hepatocytes. (clevelandclinic.org)
Bile duct cancer forms in a bile duct, which is a tube that carries bile (fluid made by the liver that helps digest fat) between the liver and gallbladder and the intestine. (uvahealth.com)
This condition is treated with surgery, using part of the newborn's intestine to form bile ducts or to reroute the drainage of bile through the intestine. (virginiamason.org)
The bile duct is the pipe that drains the bile from the liver into the intestine. (uwhealth.org)
When the main bile duct is removed, another way for the bile to drain into the intestine has to be created. (uwhealth.org)
This is done by selecting a piece of the bowel, making a small opening in it, and then connecting the bile duct remaining with the liver directly to the intestine. (uwhealth.org)
A new duct is created by connecting the duct openings in the liver and to the intestine. (cancersupportcommunity.org)

Interlobar ducts (between the main hepatic ducts and the interlobular ducts) - pseudostratified columnar epithelium. (wikipedia.org)

Hoag's state-of-the-art diagnostic technologies provide our team with the latest modalities in the accurate diagnosis of bile duct cancer and other disorders. (hoag.org)

Expert-reviewed information summary about the treatment of bile duct cancer. (oncolink.org)
This PDQ cancer information summary has current information about the treatment of bile duct cancer. (oncolink.org)
That's why it's important to seek care from a center that provides a multidisciplinary, specialized team experienced in the accurate diagnosis and treatment of bile duct cancer. (hoag.org)

Blockage of the bile duct may also cause the gallbladder to become enlarged. (britannica.com)
A dye is injected into the tube, which can show a narrowing or blockage of the bile duct. (bccancer.bc.ca)
If the blockage is caused by cancer, the duct may need to be widened. (mountsinai.org)

Individuals who eat undercooked fish are at risk of a parasitic infection, called Chinese liver fluke that increases the risk of developing bile duct infections and cancer. (virginiamason.org)

When you eat, your gallbladder pushes the bile into tubes called bile ducts. (medlineplus.gov)
Intrahepatic ducts are a system of smaller tubes within the liver that collect and transport bile to the extrahepatic ducts. (healthline.com)
After four weeks, the cells had fully covered the miniature scaffolding resulting in artificial tubes which exhibited key features of a normal, functioning bile duct. (fightaging.org)
Bile duct cancer describes a type of cancer that forms in the bile ducts (slender tubes) that carry the digestive fluid bile through the liver. (hoag.org)

The cancer is more common in Southeast Asia because infection by the liver fluke parasite - which causes chronic inflammation of the bile duct - is much more common there. (medicalnewstoday.com)
Gallbladder cancer is one of the most common biliary tract cancer and is caused largely due to chronic inflammation of the bile duct. (medindia.net)

Endoscopic retrograde cholangiopancreatographic cholangiogram demonstrating a long bile duct stricture that represents external compression by gallbladder cancer. (medscape.com)
Bile duct cancer differs from gallbladder cancer in that it is distributed more evenly between males and females, and the course is more prolonged. (medscape.com)
Enju Liu and colleagues studied 627 cancer patients out of which 328 had gallbladder cancer, 68 had ampulla of Vater and 191 had extra hepatic bile duct cancer. (medindia.net)
Join the AACR in supporting research to find better ways to prevent and treat gallbladder cancer and bile duct cancer. (aacr.org)
Gallbladder cancer and bile duct cancer are relatively rare forms of cancer. (aacr.org)
How Do Gallbladder Cancer and Bile Duct Cancer Develop? (aacr.org)

Operative common bile duct imaging by operative cholangiography and flexible choledochoscopy. (springer.com)
A cholangiography is an X-ray of the bile ducts. (healthline.com)
The bile duct is evaluated by hepatic function tests, cross-sectional imagings like magnetic resonance cholangiography, computerized tomography, trans-abdominal ultrasound or by endoscopic diagnostic and therapeutic procedures like endoscopic retrograde cholangiopancreatography, cholangioscopy and endoscopic ultrasound. (intechopen.com)
Cholangiography - A dye is injected into the bile duct with a thin needle and x-ray pictures are taken. (bccancer.bc.ca)
To determine the correlation between baseline characteristics of bile ducts and intraductal volume of the biliary tree by CT cholangiography and MELD score and the Mayo risk score in patients with PSC. (clinicaltrials.gov)
To determine the correlation between change in characteristics of bile ducts and intraductal volume of the biliary tree by CT cholangiography and change in MELD score and the Mayo risk score after 2-years of follow-up as compared with baseline. (clinicaltrials.gov)
Cholangiography is an invasive test that uses x-rays and a large needle inserted into the liver to examine the gallbladder and bile ducts. (hoag.org)

Learn about the types of bile duct cancer, risk factors, clinical features, staging, and treatment for bile duct cancer in this expert-reviewed summary. (oncolink.org)

If you are diagnosed with bile duct cancer, the health professional looking after your care will discuss the treatment options with you. (nidirect.gov.uk)
It is reasonable to believe that this reflects the position for people in Northern Ireland who are diagnosed with bile duct cancer. (nidirect.gov.uk)
My mom was just diagnosed with Bile Duct Cancer. (cancer.org)
Only 5 percent of those diagnosed with bile duct cancer are alive a year later. (opposingviews.com)

It is essential to be aware whether the bile duct can be detached by surgery, when planning for treatment. (news-medical.net)
Krauss H, Kern E. Some current problems of biliary tract surgery: indication and technique for choledochotomy, intra-operative cholangiomanometry, primary closure of the common bile duct. (springer.com)
In order to plan treatment, it is important to know if the bile duct cancer can be removed by surgery . (cancer.gov)
Among infants who underwent surgery to repair bile ducts that do not drain properly (biliary atresia), the administration of high-dose steroid therapy following surgery did not significantly improve bile drainage after 6 months, although a small clinical benefit could not be excluded, according to a study in the May 7 issue of JAMA , a theme issue on child health. (eurekalert.org)
Hepatoportoenterostomy (surgery to improve bile drainage) results in successful bile drainage in only about half of patients with biliary atresia treated in the United States, underscoring the need for additional therapies to improve survival without liver transplantation, according to background information in the article. (eurekalert.org)
There have been conflicting reports regarding the effectiveness of the use of corticosteroids to improve bile flow following surgery. (eurekalert.org)
Jorge A. Bezerra, M.D., of Cincinnati Children's Hospital Medical Center, Cincinnati, and colleagues randomly assigned 140 infants (average age, 2.3 months) to receive high-dose steroid therapy or placebo following surgery to improve bile drainage. (eurekalert.org)
The researchers found that the proportion of infants with improved bile drainage was not significantly improved by steroids at 6 months following surgery (58.6 percent of steroids group vs 48.6 percent of placebo group). (eurekalert.org)
Bile duct injury brings about serious complications, and the outcome of the reparative surgery depends on the gravity of the injury intraoperative conditions and the technique chosen 1-4 . (scielo.br)
ConclusionEctopic biliary drainage into the stomach is extremely rare, but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if required. (medworm.com)
The main treatment for bile duct cancer is surgery. (bostonscientific.com)

In 2013, however, researchers at the University of Michigan discovered that a specific kind of genetic alteration in the fibroblast growth factor receptor (FGFR) pathway recurs in patients with bile duct cancer. (massgeneral.org)

Schulte S (1995) Embryology and congenital anomalies of the bile and pancreatic ducts. (springer.com)

This book, the proceedings of the Falk Symposium 107 on `Diseases of the Liver and the Bile Ducts - New Aspects and Clinical Implications', held in Prague, Czech Republic, on April 30-May 2, 1998, brings together scientists and clinicians to highlight the most recent advances in molecular biology, physiology, diagnosis and therapy of diseases of the biliary system. (bookdepository.com)

After you eat, the gallbladder releases bile to help in digestion and fat absorption. (healthline.com)
Its main function is to transport bile, a fluid that aids in the digestion of the fats in foods. (moffitt.org)
It collects and stores bile - a fluid made by the liver to aid with digestion of fats. (aacr.org)
This network begins in the liver where many small ducts collect bile (a fluid made by the liver to break down fats during digestion ). (oncolink.org)
Bile is produced by the liver and is important for fat digestion. (oncolink.org)
The production of bile makes the liver an important organ within digestion, as it emulsifies fat, much like dish soap acts on fat and grease to split it in. (reference.com)
Bile, released after a meal containing fats, aids in absorption and digestion of the fat. (mountsinai.org)

According to MedicalHealthTests, a pipida scan is a test designed to determine the functional ability of the gall bladder and related parts in the bile del. (reference.com)
The liver is the organ that produces gall (bile) in the first place and has much more room to store this type of congestion. (curezone.com)

Researchers are looking at radiosensitizers to treat bile duct cancer. (cancer.net)

Distal bile duct cancer is the most common type of bile duct cancer after intrahepatic bile duct cancer. (news-medical.net)
Complications experienced by bile duct cancer patients after they are treated with pancreaticoduodenectomy and whipple procedures for distal bile duct cancer are as follows. (news-medical.net)
Around 47% of patients were affected by distal bile duct cancer for the second time, which indicates that 53% of patients do not experience recurrence during follow-up. (news-medical.net)

Management of diseases of the bile duct requires a multi-disciplinary team which includes primary care physicians, gastroenterologists, surgeons, medical and radiation oncologists. (intechopen.com)

Your liver makes a digestive juice called bile. (medlineplus.gov)
The researchers wanted to find out whether this might be true of the bile duct as it is for other parts of the digestive system. (medicalnewstoday.com)
A 2000 study in Greece found that blueberry juice significantly improved visualization of both the common bile duct and main pancreatic duct, which carries digestive fluids. (thefreedictionary.com)
As part of the digestive system, bile ducts help digest food properly. (cancertutor.com)

Anatomy40

Organisms8

Diseases70

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Phenomena and Processes5

Disciplines and Occupations1

Technology, Industry, Agriculture1

Health Care7

Bile duct epithelial cells exposed to alpha-naphthylisothiocyanate produce a factor that causes neutrophil-dependent hepatocellular injury in vitro. (1/1207)

Transfer of the 1-pro-R and the 1-pro-S hydrogen atoms of ethanol in metabolic reductions in vivo. (2/1207)

Effect of its demethylated metabolite on the pharmacokinetics of unchanged TAK-603, a new antirheumatic agent, in rats. (3/1207)

Complications of cholecystectomy: risks of the laparoscopic approach and protective effects of operative cholangiography: a population-based study. (4/1207)

Investigation of bile ducts before laparoscopic cholecystectomy. (5/1207)

Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver. (6/1207)

Aquaporin water channels in gastrointestinal physiology. (7/1207)

Dihydropyrimidine dehydrogenase activity and fluorouracil pharmacokinetics with liver damage induced by bile duct ligation in rats. (8/1207)

Bile Ducts

Common Bile Duct

Bile

Bile Duct Diseases

Bile Acids and Salts

Bile Ducts, Extrahepatic

Bile Duct Neoplasms

Bile Ducts, Intrahepatic

Common Bile Duct Diseases

Cholestasis

Pancreatic Ducts

Gallstones

Adenoma, Bile Duct

Common Bile Duct Neoplasms

Cholangiopancreatography, Endoscopic Retrograde

Cholangiography

Hepatic Duct, Common

Cholestasis, Extrahepatic

Cystic Duct

Cholelithiasis

Thoracic Duct

Cholecystectomy, Laparoscopic

Biliary Tract

Jaundice, Obstructive

Cholecystectomy

Cholangitis

Biliary Tract Surgical Procedures

Ligation

Choledocholithiasis

Sphincterotomy, Endoscopic

Gallbladder

Biliary Tract Diseases

Salivary Ducts

Liver

Bile Pigments

Ampulla of Vater

Bile Canaliculi

Cholangiopancreatography, Magnetic Resonance

Biliary Fistula

Cholangiocarcinoma

Wolffian Ducts

Sphincter of Oddi

Cholestasis, Intrahepatic

Mullerian Ducts

Bile Reflux

Choledochal Cyst

Liver Cirrhosis, Biliary

Biliary Atresia

Taurocholic Acid

Choledochostomy

Drainage

Ursodeoxycholic Acid

Pancreatitis

Bilirubin

Cholangitis, Sclerosing

Gallbladder Neoplasms

Cholic Acids

Chenodeoxycholic Acid

Jejunostomy

Jaundice

Kidney Tubules, Collecting

Cholagogues and Choleretics

Biliary Tract Neoplasms

Nasolacrimal Duct

Liver Diseases

Cholecystitis

Anastomosis, Roux-en-Y

Ejaculatory Ducts

Lithotripsy

Hepatectomy

Dilatation, Pathologic

Lithiasis

1-Naphthylisothiocyanate

Cholic Acid

Deoxycholic Acid

Intraoperative Complications

Iatrogenic Disease

Sphincterotomy, Transhepatic

Anastomosis, Surgical

Lithocholic Acid