A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.
Organic matter in a state of advanced decay, after passing through the stages of COMPOST and PEAT and before becoming lignite (COAL). It is composed of a heterogenous mixture of compounds including phenolic radicals and acids that polymerize and are not easily separated nor analyzed. (E.A. Ghabbour & G. Davies, eds. Humic Substances, 2001).
Encyclopedias as Topic
Chromatography, High Pressure Liquid
Seedless nonflowering plants of the class Filicinae. They reproduce by spores that appear as dots on the underside of feathery fronds. In earlier classifications the Pteridophyta included the club mosses, horsetails, ferns, and various fossil groups. In more recent classifications, pteridophytes and spermatophytes (seed-bearing plants) are classified in the Subkingdom Tracheobionta (also known as Tracheophyta).
Gymnosperms are a group of vascular plants whose seeds are not enclosed by a ripened ovary (fruit), in contrast to ANGIOSPERMS whose seeds are surrounded by an ovary wall. The seeds of many gymnosperms (literally, "naked seed") are borne in cones and are not visible. Taxonomists now recognize four distinct divisions of extant gymnospermous plants (CONIFEROPHYTA; CYCADOPHYTA; GINKGOPHYTA; and GNETOPHYTA).
Grape Seed Extract
Gene Expression Regulation, Plant
Genus of perennial plants in the family CLUSIACEAE (sometimes classified as Hypericaceae). Herbal and homeopathic preparations are used for depression, neuralgias, and a variety of other conditions. Hypericum contains flavonoids; GLYCOSIDES; mucilage, TANNINS; volatile oils (OILS, ESSENTIAL), hypericin and hyperforin.
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.
Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. (1/171)We have previously reported that proanthocyanidins extracted from grape seeds possess growth-promoting activity toward murine hair epithelial cells in vitro and stimulate anagen induction in hair cycle progression in vivo. This report constitutes a comparison of the growth-promoting activity of procyanidin oligomers and the target cells of procyanidins in the skin. Results show that procyanidin dimer and trimer exhibit higher growth-promoting activity than the monomer. The maximum growth-promoting activity for hair epithelial cells with procyanidin B-2, an epicatechin dimer, reached about 300% (30 microM) relative to controls (= 100%) in a 5 d culture. Optimum concentration of procyanidin C-1, an epicatechin trimer, was lower than that of procyanidin B-2; the maximum growth-promoting activity of procyanidin C-1 was about 220% (3 microM). No other flavonoid compounds examined exhibit higher proliferative activities than the procyanidins. In skin constituent cells, only epithelial cells such as hair keratinocytes or epidermal keratinocytes respond to procyanidin oligomers. Topical application of 1% procyanidin oligomers on shaven C3H mice in the telogen phase led to significant hair regeneration [procyanidin B-2, 69.6% +/- 21.8% (mean +/- SD); procyanidin B-3, 80.9% +/- 13.0%; procyanidin C-1, 78.3% +/- 7.6%] on the basis of the shaven area; application of vehicle only led to regeneration of 41.7% (SD = 16.3%). In this paper, we demonstrate the hair-growing activity of procyanidin oligomers both in vitro and in vivo, and their potential for use as agents to induce hair growth. (+info)
Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. (2/171)Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this study, we examined the inhibitory effects of black tea polyphenols, including theaflavin (TF-1), a mixture (TF-2) of theaflavin-3-gallate (TF-2a) and theaflavin-3'-gallate (TF-2b), theaflavin-3,3'-digallate (TF-3) and the thearubigin fraction on the autophosphorylation of the EGF and PDGF receptors in A431 cells and mouse NIH3T3 fibroblast cells, respectively. First, we examined the effects of these polyphenols on the proliferation of A431 and NIH3T3 cells. Both EGCG and TF-3 strongly inhibited the proliferation of A431 and NIH3T3 cells more than the other theaflavins did. In cultured cells with pre-treatment of tea polyphenol, TF-3 was stronger than EGCG on the reduction of EGF receptor and PDGF receptor autophosphorylation induced by EGF and PDGF, respectively. Other theaflavins slightly reduced the autophosphorylation of the EGF and PDGF receptors; furthermore, TF-3 could reduce autophosphorylation of the EGF receptor (or PDGF receptor) even with co-treatment with EGF (or PDGF) and TF-3, but EGCG was inactive under these conditions. In addition, TF-3 was stronger than EGCG in blocking EGF binding to its receptor. These results suggest that not only the green tea polyphenol, EGCG, but also the black tea polyphenol, TF-3, have an antiproliferative activity on tumor cells, and the molecular mechanisms of antiproliferation may block the growth factor binding to its receptor and thus suppress mitogenic signal transduction. (+info)
Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. (3/171)Procyanidins present in grape seeds are known to exert anti-inflammatory, anti-arthritic and anti-allergic activities, prevent skin aging, scavenge oxygen free radicals and inhibit UV radiation-induced peroxidation activity. Since most of these events are associated with the tumor promotion stage of carcinogenesis, these studies suggest that grape seed polyphenols and the procyanidins present therein could be anticarcinogenic and/or anti-tumor-promoting agents. Therefore, we assessed the anti-tumor-promoting effect of a polyphenolic fraction isolated from grape seeds (GSP) employing the 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol 13-acetate (TPA)-promoted SENCAR mouse skin two-stage carcinogenesis protocol as a model system. Following tumor initiation with DMBA, topical application of GSP at doses of 0.5 and 1.5 mg/mouse/application to the dorsal initiated mouse skin resulted in a highly significant inhibition of TPA tumor promotion. The observed anti-tumor-promoting effects of GSP were dose dependent and were evident in terms of a reduction in tumor incidence (35 and 60% inhibition), tumor multiplicity (61 and 83% inhibition) and tumor volume (67 and 87% inhibition) at both 0.5 and 1.5 mg GSP, respectively. Based on these results, we directed our efforts to separate and identify the individual polyphenols present in GSP and assess their antioxidant activity in terms of inhibition of epidermal lipid peroxidation. Employing HPLC followed by comparison with authentic standards for retention times in HPLC profiles, physiochemical properties and spectral analysis, nine individual polyphenols were identified as catechin, epicatechin, procyanidins B1-B5 and C1 and procyanidin B5-3'-gallate. Five of these individual polyphenols with evident structural differences, namely catechin, procyanidin B2, procyanidin B5, procyanidin C1 and procyanidin B5-3'-gallate, were assessed for antioxidant activity. All of them significantly inhibited epidermal lipid peroxidation, albeit to different levels. A structure-activity relationship study showed that with an increase in the degree of polymerization in polyphenol structure, the inhibitory potential towards lipid peroxidation increased. In addition, the position of linkage between inter-flavan units also influences lipid peroxidation activity; procyanidin isomers with a 4-6 linkage showed stronger inhibitory activity than isomers with a 4-8 linkage. A sharp increase in the inhibition of epidermal lipid peroxidation was also evident when a gallate group was linked at the 3'-hydroxy position of a procyanidin dimer. Procyanidin B5-3'-gallate showed the most potent antioxidant activity with an IC(50) of 20 microM in an epidermal lipid peroxidation assay. Taken together, for the first time these results show that grape seed polyphenols possess high anti-tumor-promoting activity due to the strong antioxidant effect of procyanidins present therein. In summary, grape seed polyphenols in general, and procyanidin B5-3'-gallate in particular, should be studied in more detail to be developed as cancer chemopreventive and/or anticarcinogenic agents. (+info)
Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved. (4/171)ras gene mutation, which perpetually turns on the growth signal transduction pathway, occurs frequently in many cancer types. The mouse epidermal JB6 cell line has been transfected with a mutant H-ras gene to mimic carcinogenesis in vitro. These transformed cells (30.7b Ras 12) are able to grow in soft agar, exhibiting anchorage independence and high endogenous activator protein 1 (AP-1) activity, which can be detected by a stable AP-1 luciferase reporter. The present study investigated the ability of different pure green and black tea polyphenols to inhibit this ras signaling pathway. The major green tea polyphenols (catechins), (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin, (-)-epicatechin-3-gallate, (-)-epicatechin, and their epimers, and black tea polyphenols, theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate (TFdiG), were compared with respect to their ability to inhibit the growth of 30.7b Ras 12 cells and AP-1 activity. All of the tea polyphenols except (-)-epicatechin showed strong inhibition of cell growth and AP-1 activity. Among the catechins, both the galloyl structure on the B ring and the gallate moiety contributed to the growth inhibition and AP-1 activity; the galloyl structure appeared to have a stronger effect on the inhibitory action than the gallate moiety. The epimers of the catechins showed similar inhibitory effects on AP-1 activity. The addition of catalase to the incubation of the cells with EGCG or TFdiG did not prevent the inhibitory effect on AP-1 activity, suggesting that H2O2 does not play a significant role in the inhibition by tea polyphenols. Both EGCG and TFdiG inhibited the phosphorylation of p44/42 (extracellular signal-regulated kinase 1 and 2) and c-jun without affecting the levels of phosphorylated-c-jun-NH2-terminal kinase. TFdiG inhibited the phosphorylation of p38, but EGCG did not. EGCG lowered the level of c-jun, whereas TFdiG decreased the level of fra-1. These results suggest that tea polyphenols inhibited AP-1 activity and the mitogen-activated protein kinase pathway, which contributed to the growth inhibition; however, different mechanisms may be involved in the inhibition by catechins and theaflavins. (+info)
Protection against peroxynitrite by cocoa polyphenol oligomers. (5/171)Flavonoids, natural plant constituents, protect against peroxynitrite and can thereby play a role in defense against this mediator of inflammation. Procyanidin oligomers of different size (monomer through nonamer), isolated from the seeds of Theobroma cacao, were examined for their ability to protect against peroxynitrite-dependent oxidation of dihydrorhodamine 123 and nitration of tyrosine. By molarity, oligomers were more effective than the monomeric epicatechin; the tetramer was particularly efficient at protecting against oxidation and nitration reactions. These results suggest that epicatechin oligomers found in cocoa powder and chocolate may be a potent dietary source for defense against peroxynitrite. (+info)
Procyanidin content and variation in some commonly consumed foods. (6/171)Procyanidins are a subclass of flavonoids found in commonly consumed foods that have attracted increasing attention due to their potential health benefits. However, little is known regarding their dietary intake levels because detailed quantitative information on the procyanidin profiles present in many food products is lacking. Therefore, the procyanidin content of red wine, chocolate, cranberry juice and four varieties of apples has been determined. On average, chocolate and apples contained the largest procyanidin content per serving (164.7 and 147.1 mg, respectively) compared with red wine and cranberry juice (22.0 and 31.9 mg, respectively). However, the procyanidin content varied greatly between apple samples (12.3-252.4 mg/serving) with the highest amounts on average observed for the Red Delicious (207.7 mg/serving) and Granny Smith (183.3 mg/serving) varieties and the lowest amounts in the Golden Delicious (92.5 mg/serving) and McIntosh (105.0 mg/serving) varieties. The compositional data reported herein are important for the initial understanding of which foods contribute most to the dietary intake of procyanidins and may be used to compile a database necessary to infer epidemiological relationships to health and disease. (+info)
Cocoa procyanidins and human cytokine transcription and secretion. (7/171)We examined whether cocoa, in its isolated procyanidin fractions (monomer through decamer), would modulate cytokine production at the levels of transcription and protein secretion in both resting and phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMC). In resting cells, interleukin (IL)-1beta and IL-4 gene expression from cocoa-treated cells varied markedly among the subjects tested. However, at the protein level, the larger fractions (pentamer through decamer) stimulated a dramatic increase in IL-1beta concentration (up to ninefold) with increasing degree of polymerization. Similarly, these larger fractions augmented IL-4 concentration by as much as 2 pg/ml, whereas the control displayed levels nearly undetectable. In the presence of PHA, gene expression also seemed to be most affected by the larger procyanidin fractions. The pentameric through decameric fractions increased IL-1 beta expression by 7-19% compared with PHA control, whereas the hexameric through decameric fractions significantly inhibited PHA-induced IL-4 transcription in the range of 71-86%. This observation at the transcription level for IL-1 beta was reflected at the protein level in PHA-stimulated PBMC. Significant reductions in mitogen-induced IL-4 production were also seen at the protein level with the hexamer, heptamer and octamer. Individual oligomeric cocoa fractions were unstimulatory for IL-2 in resting PBMC. However, when induced with PHA, the pentamer, hexamer and heptamer fractions caused a 61-73% inhibition in IL-2 gene expression. This study offers additional data for the consideration of the health benefits of dietary polyphenols from a wide variety of foods, including those benefits associated specifically with cocoa and chocolate consumption. (+info)
Reactions of peroxynitrite with cocoa procyanidin oligomers. (8/171)Peroxynitrite is a mediator molecule in inflammation, and its biological properties are being studied extensively. Flavonoids, which are natural plant constituents, protect against peroxynitrite and thereby could play an anti-inflammatory role. Procyanidin oligomers of different sizes (monomer through nonamer), isolated from the seeds of Theobroma cacao, were recently examined for their ability to protect against peroxynitrite-dependent oxidation of dihydrorhodamine 123 and nitration of tyrosine and were found to be effective in attenuating these reactions. The tetramer was particularly efficient at protecting against oxidation and nitration reactions. Epicatechin oligomers found in cocoa powder and chocolate may be a potent dietary source for defense against peroxynitrite. (+info)
Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin.
PMID: Clin Interv Aging. 2012 ;7:275-86. Epub 2012 Jul 27. PMID: 22956863. Abstract Title: Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin. Abstract: BACKGROUND: French maritime pine bark extract (PBE) has gained popularity as a dietary supplement in the treatment of various diseases due to its polyphenol-rich ingredients. Oligometric proanthocyanidins (OPCs), a class of bioflavonoid complexes, are enriched in French maritime PBE and have antioxidant and anti-inflammatory activity. Previous studies have suggested that French maritime PBE helps reduce ultraviolet radiation damage to the skin and may protect human facial skin from symptoms of photoaging. To evaluate the clinical efficacy of French maritime PBE in the improvement of photodamaged facial skin, we conducted a randomized trial of oral supplementation with PBE.METHODS: One hundred and twelve women with mild to moderate photoaging of the skin were randomized ...
French Maritime Pine Bark Extract Side Effects | LIVESTRONG.COM
French Maritime Pine Bark Extract, also simply known as pine bark extract and marketed under the trade name Pycnogenol, is a medicinal substance derived...
Analysis of black tea theaflavins by non-aqueous capillary electrophoresis. - Semantic Scholar
In this study a new capillary electrophoresis (CE) method was developed to quantify the four major theaflavins occurring in black tea. Where aqueous based CE methods showed poor selectivity and considerable band broadening, non-aqueous CE achieved baseline separation of the theaflavins within 10 min. The effects of the organic solvent composition and background electrolyte concentration on the separation selectivity and electrophoretic mobilities were investigated. Our optimized separation solution consisted of acetonitrile-methanol-acetic acid (71:25:4, v/v) and 90 mM ammonium acetate. This method was used to analyze three black tea samples.
Life Extension - Life Extension - Arthromax With Theaflavins And Apresflex 120 Vegetarian Capsules
ArthroMax with Theaflavins & AprèsFlex 120 vegetarian capsuleAs people grow older, age-related stiffness and discomfort in the joints becomes a fact of life. Activities once routine become a challenge as limited mobility hampers your every move. You now have a more potent option to provide broad-spectrum support for aging joints. ArthroMax is available with Black Tea Theaflavins (without UC-II) to protect against immune attack in the joints via a separate mechanism. Inflammatory reactions are regulated by a series of cytokines produced in the body. Normal aging results in an unfavorable balance of these cytokines that contributes to persistent inflammatory conditions. Studies have shown that a special fraction found in black tea suppresses proinflammatory cytokines at the genomic level. Scientists have found that these com-pounds called theaflavins uniquely downregulate the expression of genes and cytokines associated with inflammatory conditions. ArthroMax with Theaflavins and AprèsFlex
Frontiers | Amentoflavone Affects Epileptogenesis and Exerts Neuroprotective Effects by Inhibiting NLRP3 Inflammasome |...
Brain inflammation is one of the main causes of epileptogenesis, a chronic process triggered by various insults, including genetic or acquired factors that enhance susceptibility to seizures. Amentoflavone, a naturally occurring biflavonoid compound that has anti-inflammatory effects, exerts neuroprotective effects against nervous system diseases. In the present study, we aimed to investigate the effects of amentoflavone on epilepsy in vivo and in vitro and elucidate the underlying mechanism. The chronic epilepsy model and BV2 microglial cellular inflammation model were established by pentylenetetrazole (PTZ) kindling or lipopolysaccharide (LPS) stimulation. Cognitive dysfunction was tested by Morris water maze while hippocampal neuronal apoptosis was evaluated by immunofluorescence staining. The levels of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome complexes and inflammatory cytokines were determined using quantitative real-time polymerase chain reaction, Western
Herbal Source of Amentoflavone - Similar Threads
The biflavonoid amentoflavone was identified in research as an antagonist of the very same receptor. I would like to know whether a Ginkgo Biloba-leaf extract may contain a significant amount of amentoflavone.
A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology
There is much evidence showing that PYC has beneficial effects on physiological functions. Results from ongoing clinical research are required to confirm and extend previous observations.
Life Extension ArthroMAX with Theaflavin & AprsFlex(Not to be sold in - Healthy Planet Shopping
ArthroMAX with Theaflavin & AprsFlex Not to be sold in Belgium 120 VegCapProduct DescriptionArthroMax R with Theaflavins & AprsFlex R is one of our ArthroMax R family of joint supplements. It combines five innovative nutrients to support joint and connective tissue health and mobility.Black tea theaflavins, MSM
Exploring the potential of black tea based flavonoids against hyperlipidemia related disorders | Lipids in Health and Disease |...
In recent decade, Hyperlipidemia related disorders like obesity, hypercholesterolemia and diabetes are considered as the leading killers for mankind. Fundamental nexus between nutrition and health diverting the consumers focus towards plant based natural products as a remedy against various metabolic syndrome. Considering this, present study was conducted to explicate the role of black tea polyphenols such as Theaflavins and thearubigins therapeutic potential to tackle targeted maladies especially oxidative stress related disorders like hypercholesterolemia and diabetes. The mandate of current investigation was to explore the hypoglycemic and hypocholestrolemic perspective of isolated theaflavin and thearubigins through a model feeding trial. For the purpose, theaflavin & thearubigins were isolated from black tea through solvent partition method and utilize to form three types of nutraceutical drinks (theaflavin, thearubigins & theaflavin + thearubigins based) alongside control to be further utilized in
Pine bark extract shows promise against heart failure
Extracts from French maritime pine bark may protect against heart failure, if a new study with mice can be translated into humans.
KAL Pycnogenol® -- 50 mg - 60 Tablets - Vitacost
Pycnogenol is a powerful antioxidant containing a complex of more than 40 water-soluble antioxidants, including a variety of procyanidin compounds and organic acids. It is intended to provide nutritive support for normal, healthy circulation, skin and connective tissue. French maritime pine bark extract is protected by U.S. patents 4,698,360 and 5,720,956 ...
Insights into interaction profile and inhibitory potential of amentoflavone with ?-glucosidase, tyrosinase and 15-lipoxygenase...
Insights into interaction profile and inhibitory potential of amentoflavone with ?-glucosidase, tyrosinase and 15-lipoxygenase as validated therapeutic targets., Tomisin Happy Ogun
Tinnitis Symptom | Dr. Jeffrey Tucker
October 2010 Journal Panminerva Medica, • Daily supplements of French maritime pine bark extract (Pycnogenol) may ease tinnitus. • It may improve blood flow to the inner ear and therefore relieve tinnitus symptoms.. •Impaired blood flow to the ear is a common cause for tinnitus. Patients should try 100 to 150 milligrams per day of Pycnogenol (pine bark). Order @ www.DrJeffreyTucker.meta-ehealth.com •Pycnogenol is effective in a short period of time in relieving tinnitus symptoms by improving cochlear blood flow.. Panminerva Medica 52(2 Suppl 1):63-68, 2010. More ...
Polyphenols in Pycnogenol Improve Erectile Function and Lipid Profile
Pycnogenol®, the French maritime pine bark extract, may improve the symptoms of erectile dysfunction and improve circulation and blood flow, which strengthens the vascular system and manages cholesterol.
Reference - RRC(Research Resource Circulation)
Theasinensin A is one of the oolong tea theasinensins, which differ from green tea catechins and black tea theaflavins. In a previous study, we found that theasinesin A had a potential effect on antiinflammation since theasinensin A suppressed LPS-induced COX2 and PGE(2) production. To clarify the molecular mechanisms, we investigated the gene expression profiling in macrophage-like cells treated with theasinensin A through a genome-wide DNA microarray in the present study. Among 22,050 oligonucleotides, the expression levels of 406 genes were increased by ≥3-fold in LPS-activated RAW264 cells, 259 gene signals of which were attenuated by theasinensin A treatment (≥2-fold). Expression levels of 717 genes were decreased by ≥3-fold in LPS-activated cells, of which 471 gene signals were restored by theasinensin A treatment (≥2-fold). These genes were further categorized as defense, inflammatory response, cytokines activities, and receptor activities, and some of them were confirmed by ...
ADHD treatments: Magnesium Combination Treatments for ADHD
Bloggers note: You may have read a number of references or seen a number of websites for ADHD and multiple other ailments touting the benefits of compounds such as pycnogenol (also known as French Maritime Pine Bark Extract), and grape-seed extract. As of now, I am neutral as far as using products such as these. However, it is important to note that the majority of the benefits derived from treatments such as these are due to their antioxidant effects, which are quite powerful by the way (however, other functions besides mere antioxidant effects have been suggested and are entirely possible). Additionally, these supplements can be quite costly. It is this bloggers opinion that similar effects and benefits can be seen with vitamin C and E supplementation for a cheaper price. Nonetheless, the large number of studies supporting the effectiveness of pycnogenol and grape-seed extract does warrant further investigation and potential success as an ADHD treatment option. With youre doctors ...
Preparation of procyanidin B2 from apple pomace and its inhibitory effect on the expression of cyclooxygenase-2 in...
Dimeric procyanidin B2 (PB2) is one of phenolic compounds in apple pomace, an agro-industrial byproduct in apple juice processing. This work focused on purification of PB2 from apple pomace using sephadex column chromatography and its potential effect on lipopolysaccharide (LPS)-induced inflammation using RAW264.7 macrophages. PB2 with the purity of 72.28 Â± 1.85% was successfully afforded using resin and gel column chromatographic technique. Anti-inflammatory tests suggested that the expression of cyclooxygenase-2 (COX-2) in LPS-induced murine RAW264.7 macrophages was suppressed in a PB2 concentration-dependent manner. PB2 at no less than 50 Âµg mL-1 could significantly suppress inflammation in the LPS-induced cells. Moreover, this suppressive effect was not correlated with PB2 pretreating. However, the COX-2 expression was not reduced in LPS pretreatment way followed by PB2 exposure, which suggested that PB2 has no repairing function. The results showed that high pure PB2 prepared from ...
Pynocare White - Mega BiO-LiFE
ENG 中文 BM PYNOCARE WHITE Overview For healthy ravishing skin from inside out. How does Pynocare White helps in skin health? It provides free radical defence function, UV protecting function, and moisturizing effect with the ingredients PiWhiteTM (French maritime pine bark extract), vitamin C, vitamin E, D-salina extract (mixed carotenoids), LycoskinTM (tomato extract), and Lucent-PTM (rice-derived ceramide). French […]
|p|This premium French maritime pine bark extract contains numerous bioactive compounds that support capillary and connective tissue function and provide antioxidant protection.|sup|†|/sup| Pycnogenol|sup|®|/sup| is a powerful scavenger of free radicals i
Pycnogenol Boosts Hyaluronic Acid (44%) in Skin Study
In a clinical trial on 20 elderly women, supplementation with the French maritime pine bark extract Pycnogenol improved a number of key skin health markers. The study is published in the journal Skin Pharmacology and Physiology
Pycnogenol®, 100 mg, 60 vegetarian capsules - Life Extension
Our Pycnogenol® vascular health supplement is a patented extract of French maritime pine bark extensively studied to support overall wellness & longevity.
Procyanidin B2 Improves Oocyte Maturation and Subsequent Development
Procyanidin B2 improves oocyte maturation and subsequent development in Type 1 diabetic mice by promoting mitochondrial function.
In vivo bioavailability, absorption, excretion, and pharmacokinetics of [14C]procyanidin B2 in male rats. | Sigma-Aldrich
Sigma-Aldrich offers abstracts and full-text articles by [Stavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J King, Jonathan E Brown, Michael N Clifford].
Theaflavin Standardized Extract, 30 capsules | Life Extension
Theaflavin Standardized Extract contains a number of beneficial flavonoids found naturally in tea leaves that help support levels of cholesterol that are already within the normal range.
Rapid determination of theaflavins by HPLC with a new monolithic column | Czech Journal of Food Sciences
Rapid determination of theaflavins by HPLC with a new monolithic column | Jianyong Zhang, Hongchun Cui, Heyuan Jiang, Lei Fang, Weiwei Wang, Wei Su, Chunhua Xiong | Agricultural Journals
Bethard bonus, Tiki Tumble, Www free slots : Cheerleaderhandbook
If you need to discover what great adventures in your jackpot magic sweetheart, then tiki tumble simply youve go to the best area. In about cases, victimization medication to process the excitement put up besides supporter. Emma, a writer, met her husband anthony, an electrician, via tinder! Its hard to be optimistic. To get started today, just visit audible. Walters, who says he only recently discovered the distortion button on his guitar amp, performs in a jacket with a patch of heavy-metal band megadeath.. Examples amentoflavone bis apigenin coupled at 8 tiki tumble and 3 positions lophirone l and lophirone m found in lophira alata sulcatone a a naturally occurring biflavonoid isolated from ouratea sulcata. The suit of the top card in the draw pile is this by default, but any player can change it if desired. Ralph lauren custom fit pima stretch mesh polo xl ray ban brown justin bracelet homme hermes pas cher nike lebron 14 gold pink mackage jackets kijiji montreal the north face live ...
Procyanidin B2 inhibits high glucose‑induced epithelial‑mesenchymal transition in HK‑2 human renal proximal tubular epithelial...
Sigma-Aldrich offers abstracts and full-text articles by [Dandan Li, Tingbao Zhao, Jianzhong Meng, Ying Jing, Fengyu Jia, Ping He].
Uncut- A New Encapsulated Pre-Workout From Applied Nutriceuticals - AnabolicMinds.com - Page 13
Originally Posted by AZMIDLYF What ingredient is providing the pump? Amentoflavone. Also Im pretty sure this was designed to be used with NO Uptake.
French maritime pine bark extract (Pinus pinaster) - B-Healthy
4-Beta-D-glucoside, arbre dor (French), bioflavonoid, borovice hvezdicovit (Czech), caffeic acid, catechin, condensed tannins, epicatechin, ferulic acid, Flavangenol , free glucose, French maritime pine bark extract, French Pinus maritime bark, gallic acid, L-(feruloyl)-beta-D-glucose, L-(p-coumaroyl)-beta-D-glucose, maritime pine tree bark, merim nd (Estonian), oligomeric proanthocyanidin complexes, OPCs, PCOs, p-coumaric acid, phenolcarbonic acids, phenolic acids, phenolic fruit acid, p-hydroxybenzoic acid, pi mar tim (Catalan), pi pinastre (Catalan), pin de Bordeaux (French), pin de Corte (French), pin des Landes (French), pin maritime (French), pin m sog en (French), Pinaceae (family), pinastro (Italian, Spanish), pinheiro-bravo (Portuguese), pino costiero (Italian), pino gallego (Spanish), pino mar timo (Spanish), pino marittimo (Italian), pino resinero (Spanish), pino rodeno (Spanish), pino rubial (Spanish), Pinus pinaster, Pinus maritima, polyphenols, proanthocyanidins, procyanidins, ...
Amentoflavone - Wikipedia
Amentoflavone is a biflavonoid (bis-apigenin coupled at 8 and 3 positions, or 3′,8′′-biapigenin) constituent of a number of plants including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Hypericum perforatum (St. Johns Wort) and Xerophyta plicata. Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body. It is also an inhibitor of human cathepsin B. Amentoflavone has a variety of in vitro activities including antimalarial activity, anticancer activity (which may, at least in part, be mediated by its inhibition of fatty acid synthase), and antagonist activity at the κ-opioid receptor (Ke = 490 nmol L−1) as well as activity at the allosteric benzodiazepine site of the GABAA receptor as a negative allosteric modulator. Apigenin Pan X, Tan N, Zeng G, Zhang Y, Jia R (2005). Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B. Bioorg. Med. ...
CiNii 論文 - S-Phase Accumulation of Candida albicans by Anticandidal Effect of Amentoflavone...
Amentoflavone, which is a biflavone derived from various plants, has been known to possess various biological activities including anti-tumor and anti-inflammatory activity. In the previous study, we reported antifungal effect of amentoflavone isolated from an ethyl acetate extract of Selaginella tamariscina on human pathogenic fungi. Amentoflavone significantly inhibited the growth of fungal cells without hemolysis of human erythrocytes. In the present study, we investigated antifungal acting mode of amentoflavone in human pathogenic yeast Candida albicans. Anticandidal activity was exerted in an energy-independent manner presented by an antifungal assay in the presence of NaN3, which is ATP-depleting agent as a metabolic inhibitor. To investigate the effects of amentoflavone on cellular physiology in C. albicans, we performed cell cycle analysis, and the analysis showed that amentoflavone significantly arrested cell cycles during the S-phase. These results demonstrated that amentoflavone has ...
Neuroprotective Effects of Grape Seed Procyanidin Extract on
Grape seed procyanidin extract may represent a new therapeutical direction for the treatment of ischemia-reperfusion brain injury.
Pycnogenol (French Maritime Pine Bark Extract) Shown To Improve Visible Signs Of Aging In New Study - Redorbit
Pycnogenol® reduced skin wrinkles by three percent and increased skin smoothness by six percent. To date, Pycnogenol® is the only natural supplement that stimulates hyaluronic acid production in human skin. And, we are encouraged by the molecular evidence confirmed in this study that shows nutritional supplementation with Pycnogenol® benefits human skin, explains Dr. Jean Krutmann, the lead researcher from the Leibniz Research Institute in Dusseldorf, Germany.. Study results confirmed Pycnogenol® improved skin at a physiological and molecular level. Pycnogenol® increased hyaluronic acid in women by 44 percent after 12 weeks of supplementation. Hyaluronic acid binds large quantities of water in the skin and in other tissues, such as cartilage. An increased amount of hyaluronic acid explains the increased skin hydration, higher elasticity and overall smoother skin appearance found in women taking Pycnogenol®.. This exciting and technically advanced investigation with women representing ...
Absorption and Metabolism of Dietary Cocoa Procyanidins in Humans - Full Text View - ClinicalTrials.gov
Flavanols and their oligomeric derivatives, the procyanidins, are plant-derived compounds normally present in the human diet. Accumulating data demonstrate a causal role for flavanols in mediating the cardiovascular benefits associated with the consumption of flavanol-/procyanidin-containing foods. Evidence for a direct, causal role for procyanidins in this context is far less profound. As this is often based on the poor absorption of procyanidins, it has been proposed that procyanidins may indirectly contribute to the systemic presence of bioactive compounds via derivatives generated from the breakdown or catabolism of procyanidins in the gastrointestinal tract. These postulated breakdown products include: i) flavanols, putatively generated by acid hydrolysis in the stomach, and ii) series of phenolic compounds, including 5-(3,4-dihydroxyphenyl)-gamma-valerolactone, that are produced from procyanidin catabolism by the gut microbiome. Verification or rejection of these suppositions could ...
Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract ...
French maritime pine bark extract (Pycnogenol®) displays a variety of anti-inflammatory effects in vivo. Aim of this study was to determine whether human plasma after oral intake of Pycnogenol...
Selaginella tamariscina PFAF Plant Database
Selaginella tamariscina is an evergreen Perennial growing to 0.1 m (0ft 4in). It is in leaf 12-Jan. The flowers are hermaphrodite (have both male and female organs)Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Suitable pH: acid, neutral and basic (alkaline) soils. It can grow in semi-shade (light woodland). It prefers moist soil.
Molecules | Free Full-Text | Inhibitory Activity of Synthesized Acetylated Procyanidin B1 Analogs against HeLa S3 Cells...
Proanthocyanidins, also known as condensed tannins and/or oligomeric flavonoids, occur in many edible plants and have various interesting biological activities. Previously, we reported a synthetic method for the preparation of various procyanidins in pure form and described their biological activities. Here, we describe the synthesis of procyanidin B1 acetylated analogs and discuss their inhibition activities against HeLa S3 cell proliferation. Surprisingly, the lower-unit acetylated procyanidin B1 strongly inhibited the proliferation of HeLa S3 cells. This molecule showed much stronger inhibitory activity than did epigallocatechin-3-O-gallate (EGCG), green tea polyphenol, and dimeric compounds that included EGCG as a unit. This result suggests that the phenolic hydroxyl groups of the upper-units in flavan-3-ols are important for their inhibitory activity against cancer cell proliferation and that a hydrophobic lower unit dimer enhances this activity.
MANUFACTURING METHOD FOR THEAFLAVINS USING RAW TEA LEAVES - Patent application
0046]Milling step can be carried out at temperatures from 0° C. to 30° C. When the mixture was milled with a mixer for 3 minutes, the content of the theaflavins was substantially increased over that from the 1 minute milling process. The content of the theaflavins was measured after standing for 24 hours and 120 hours. The content of TF3G, TF3G, and TFDG was reduced after 120 hours relative to that after 24 hours, but not completely converted to TF as in Example 2. This is believed to be due to an increased content of TF3G, TF3G, and TFDG in the 3 minute shaking step, the hydrolysis reactions did not proceed to completion within 120 hours. An even longer standing time will be required. It is also believed that TF3G, TF3G, and TFDG are increased in the 3 minutes shaking step, but is not completely hydrolyzed within 120 hours, because the hydrolysis of EGCG and ECG easily proceeds while the hydrolysis of TF3G, TF3G, and TFDG hardly proceeds (comparison among Examples 2, 4, and 5). The mixer ...
IJMS | Free Full-Text | Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
Anti-bacterial effect:. Choleve is rich in theaflavins. A group of researchers from US department of Agriculture conducted a research to evaluate the antimicrobial activities of theaflavins from tea. The bacteria strain they used is Bacillus cereus (strain RM3190). The results demonstrate that theaflavins showed antimicrobial activities at nanomolar level; they were more active than were medicinal antibiotics, such as tetracycline or vancomycin, at comparable concentrations.. Reference:. Friedman M, Henika PR, Levin CE, Mandrell RE, Kozukue N: Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus. Journal of Food Protection 2006; 69(2): 354-361. Anti-viral effect:. Theaflavin derivatives and catechin derivatives are the major polyphenols in black tea and green tea, respectively. Several tea polyphenols, especially those with galloyl moiety, can inhibit HIV-1 replication with multiple mechanisms of action. Researchers showed that the theaflavin ...
Synergistic antibacterial effects of theaflavin in combination with ampicillin against hospital isolates of Stenotrophomonas...
Stenotrophomonas maltophilia is an important opportunistic nosocomial pathogen that shows intrinsic resistance to many antibiotics. This often limits treatment options and can cause lengthy hospital stays. Combination treatments are often used to combat resistance and using natural compounds such as polyphenols could give increased treatment options and even the reuse of antibiotics to which high levels of resistance have been observed. A checkerboard assay was used to determine if any synergy exists between ampicillin and the polyphenol theaflavin against 9 clinical isolates and one control isolate (NCTC 13014) of S. maltophilia. It was discovered that significant synergy (P 0.05) does exist between theaflavin and ampicillin, reducing the mean MIC of ampicillin from 12.5-22.9 µg/mL, in liquid culture, to 3.125-6.25 µg/mL. The FIC index was calculated to be 0.22-0.35 confirming synergy. From these results, significant potential for medical applications can be seen and further investigation ...
Antioxidant and membrane effects of procyanidin dimers and trimers isolated from peanut and cocoa. | Cocoa Flavanol Science
Abstract. The antioxidant and membrane effects of dimer (Dim) and trimer (Trim) procyanidins isolated from cocoa (Theobroma cacao) (B- and C-bonded) and peanut (Arachis hypogea L.) skin (A-bonded) were evaluated in phosphatidyl choline liposomes. When liposomes were oxidized with a steady source of oxidants, the above dimers and trimers inhibited to a similar extent lipid oxidation in a concentration (0.33-5 microM)-dependent manner. With respect to membrane effects, Dim A1, Dim B, Trim A, and Trim C increased (Dim A1 = Dim B and Trim A = Trim C), while Dim A2 decreased, membrane surface potential. All of the procyanidins tested decreased membrane fluidity as determined by fluorescent probes at the water-lipid interface, an effect that extended into the hydrophobic region of the bilayer. Both dimers and trimers protected the lipid bilayer from disruption by Triton X-100. The magnitude of the protection was Dim A1 , Dim A2 , Dim B and Trim C , Trim A. Thus, dimers and trimers can interact with ...
Are Nitric Oxide Supplements Good for Your Health and Well-being? - MSN Box
Nitric oxide plays an important role in erectile function. Several supplements, including L-citrulline, L-arginine, and French maritime pine bark extract, have been shown to increase nitric oxide levels in men with erectile dysfunction (ED).. A form of L-citrulline called citrulline malate not only increases nitric oxide production but also reduces muscle soreness.. Muscle soreness is an unpleasant experience that occurs after strenuous or unaccustomed exercise.. This muscle soreness is called delayed onset muscle soreness and is usually most intense 24 to 72 hours after exercise.. In one study, 41 people were randomly assigned to receive either 8 grams of citrulline malate or a placebo one hour before performing as many repetitions as possible while doing bench presses with a flat bar.. Those who received citrulline malate reported 40% less muscle soreness 24 and 48 hours after exercise compared to those who took the placebo.. Citrulline malate increases nitric oxide production, which increases ...
Amla and Pycnogenol May Powerfully Lower Dangerous C Reactive Protein and Fibrinogen Levels | EmediaHealth
As for the beneficial changes, I think these can be largely lied to the Amla and Pycnogenol supplements. Both are strong antioxidants and both have documented impact on C Reactive Protein. After examining studies on the likely effects of amla (Indian gooseberry) and Pycnogenol (French maritime pine bark), it seems like they plus nattokinase (a proteolyic enzyme) may make a powerful one-two-three punch against cardiovascular disease by lowering inflammation, clearing out blood vessels, reducing oxidative damage to lipids and cells, and lowering the amount of clot-inducing fibrinogen that in most people is far higher than they need. I mention nattokinase for two reasons. One is that the outspoken Dr. David Williams promotes the use of amla with nattokinase to reduce abnormal clotting risk in typical aging people so if you read up on amla youre likely to run across this discussion. A second is that these test results Im discussing were achieved after about 3.5 years of supplementation with ...
Pycnogenol for the Treatment of Lymphedema
The objectives of this study are to evaluate the effectiveness of Pycnogenol (French maritime pine bark extract) for arm lymphedema in women following t
Rumput Kipas/Grass Fan (Selaginella tamariscina) | CCRC
Spherical stem, clayey, fork-shaped branching or form a fan without secondary growth and green. The leaves are single, dealing, composite march, along the stem shape of the needle with 1-2 mm length and green. This plants have sporangium that reduced, found in the axillaries, greenish white while the fiber appear from the stem like sticky roots and brown. Grass fan has habitus herb, creep, little upright. Round stem, clayey, branching like a fork, without secondary growth and brownish white. Single leave, arranged in line around the stem, dealing, 1-2 mm length, smooth, and green. Spore from of the sporangium reduced in axillary and white. Root fibers, appear from the leafy stems and blackish brown (Hutapea, 1994).. 4. Spread of ...
Extracellular Signal-Regulated Kinase Is a Direct Target of the Anti-Inflammatory Compound Amentoflavone Derived from Torreya...
Mediators of Inflammation is a peer-reviewed, Open Access journal that publishes original research and review articles on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.
Human Health Benefits Evaluated in Research on Flavanols and Procyanidins
New insights into the distinct roles of flavanols and procyanidins in the human body have been provided by collaborative research by Mars, Incorporated and the University of California, Davis.
Author: Li, Shuyi / Journal: Journal of agricultural and food chemistry / Subject: pericarp - PubAg Search Results
It has been proven that A-type procyanidins, containing an additional ether bond, compared to B-type procyanidins are also bioavailable in vitro and in vivo. However, their bioavailability and absorption in the gastrointestinal tract remain uncertain. In this study, a model of the human adenocarcinoma stomach cell line (MKN-28) was established to explore the cellular transport of flavanolic monome ...
New Study: Pycnogenol(R) Reduces Heart Failure
HOBOKEN, NJ -- (MARKET WIRE) -- May 16, 2007 -- A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol®, natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart. The study...
Study Confirms Anti-inflammatory Property of Pycnogenol
Researchers at the National Research Institute on Food and Nutrition have reported that Pycnogenol, an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems.
Hay Fever Symptoms: Hay Fever Relief from this Tree
A new study has found that an antioxidant plant extract derived from the bark of the French maritime pine tree could substantially improve those nagging symptoms most of us know so well
Solgar Pycnogenol 30 mg Vegetable Capsules
Pycnogenol® is the extract from the bark of the French Maritime Pine Tree, which grows in south-west France. It is a natural, concentrated source of plant-d
Stem cells are the source of differentiated cells that constitute tissues and organs | Page 2
Supplementary MaterialsSupplemental Material kcbt-20-01-1504718-s001. inhibitor treatments) into a total cell death response when PF384 and PD901 are combined. This response was also impartial of KRAS mutation, occurring in both BxPC3 (wildtype) and MIA-PaCa-2 (mutant PDAC cells. gene is usually mutated in ~?90% of PDAC and is thought to be an early and initiating event, which in combination with cooperative genetic alterations (and and mutational status. In part the ambiguity surrounding this may relate to particular cancer types. For instance, mTOR inhibition continues to be found to diminish appearance of Mcl-1 in colorectal cancers cells, but only once mutations had been present.30 Compared, the dual PI3K/mTOR inhibitor BEZ235 acquired no influence on Mcl-1 expression in PDAC cell lines regardless of status,31 but reduced expression in ovarian cancer cell Procyanidin B1 lines.32 Additionally, while MEK inhibition is more reported to improve or stabilise appearance of Bim commonly, its been ...
Senjata Rahasia dibalik Khasiat Black Tea
Guys, ada yang suka minum Black Tea? Hmm...Aku sendiri sebenarnya bukan pecinta fanatik black tea, tapi aku gak asing dengan minuman yang satu ini. Selalu ada di kantin dan penyegar yang paling murah harganya hihihii...Gak lama ini ada tugas matakuliah yang topiknya seputar Black Tea. Setelah dikerjain dan nyari banyak referensi ternyata black tea ini…
Point of Interest!: Green tea extract: Proanthocyanidins and procyanidins
As for comments, please find a relevant post and write your comment there. Theres no point asking for help with your lotion bar on a post about conditioners as no one will see it but you. Please find something that relates by doing a search or looking at sections like hair care, newbie links, or extracts, for example, post your comments there. Itll make it easier for other people to help you if I cant find time, too. If you post something that is very clearly not related to the post in which youre asking for help, it will go unanswered by me. ...
Black Tea | Best Organic Black Teas | Art of Tea, Popularity: Award Winning, Origin: Art of Tea Blend, Mood: Rejuvenating,...
Explore Our Black Teas, Including Loose Leaf, Organic, Herbal & More. Shop Our Tea Store Online Today!, Popularity: Award Winning, Origin: Art of Tea Blend, Mood: Rejuvenating, Flavor: Fruity
Black Tea | Best Organic Black Teas | Art of Tea, Origin: Art of Tea Blend, Mood: Sleepy, Occasion: Afternoon, Flavor: Sweet
Explore Our Black Teas, Including Loose Leaf, Organic, Herbal & More. Shop Our Tea Store Online Today!, Origin: Art of Tea Blend, Mood: Sleepy, Occasion: Afternoon, Flavor: Sweet
The Many Health Benefits of Drinking Black Tea
Drinking black tea provides many health benefits. Use this guide to learn the health benefits of drinking black tea, including heart health and more.
Benefits of Black Tea And Its Side Effects | Lybrate
|P| While over indulging in anything is not good, drinking black tea in moderate amounts has a vast variety of health benefits. Black tea promotes oral healthy while h...
Is black tea good for you? | Reference.com
Consumed in moderation, black tea is beneficial. Besides temporarily boosting alertness, black tea contains helpful substances that may prevent a number of diseases and conditions, including reducing...
Ceylan black tea 100 g - Buy
Black tea is one of the varieties most consumed in the world. It is an oxidized tea, with an agreeable flavor and a slight orange color. A natural source of satiating and digestive .
Fresh - BLACK TEA AGE-DELAY FIRMING SERUM - Fresh
An age-delay treatment that smoothes the appearance of fine lines and wrinkles while providing a firmer, luminous look. Fresh, Inc.
Naturally occurring phenols
Biflavonoids Amentoflavone many (C6-C3)n,. (C6)n,. (C6-C3-C6)n n , 12 Lignins,. Catechol melanins,. Flavolans (Condensed ...
Leaflets also contain biflavonoids. Estragole is the primary volatile compound emitted from the male and female cones of C. ... Moderately Active Antibacterial Biflavonoids. Abeer Moawad, Mona Hetta, Jordan K. Zjawiony, Melissa R. Jacob, Mohamed Hifnawy, ...
The two biflavonoids, 3′-O-methyl loniflavone and loniflavone, along with luteolin and chrysin, can be isolated from the leaves ... Kumar, Neeraj; Singh, Bikram; Bhandari, Pamita; Gupta, Ajai P.; Uniyal, Sanjay K.; Kaul, Vijay K. (2005). "Biflavonoids from ...
Biflavonoids from Ochna lanceolata v t e. ...
Biflavonoids are a type of flavonoids with the general formula scheme (C6-C3-C6)2. Amentoflavone (bis-apigenin coupled at 8 and ... "Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata". Phytochemistry. 66 (16): 1922-1926. doi:10.1016/j. ... revoluta contain biflavonoids such as (2S, 2′′S)-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-O-methylamentoflavone ( ... Moderately active antibacterial biflavonoids". Planta Med. 76 (8): 796-802. doi:10.1055/s-0029-1240743. PMC 3711132. PMID ...
Williams, Christine A.; Harborne, Jeffrey B.; Tomas-Barberan A., Francisco (1987). "Biflavonoids in the primitive monocots ...
To date, the field of biochemistry of biflavonoids is still wide open. Little is known about Ochnaflavone of its natural ...
"Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis". International Journal of ...
Leaflets of C. circinalis contain biflavonoids such as (2S, 2′′S)-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-O-methylamentoflavone ( ... Phytochemical Investigation of Cycas circinalis and Cycas revoluta Leaflets: Moderately Active Antibacterial Biflavonoids. ...
... a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids". Planta Medica. 55 (2): 166-8. doi ...
Both biflavonoids were obtained in small quantities, and their structures show some new and unusual biflavonoid diversity. ... The leaves of Lophira alata afforded two new biflavonoids, lophirone L (1) and lophirone M (2), and the known luteolin and ...
... , an isolate of Garcinia dulcis, belongs to the family of biflavonoids and is an inhibitor of HMG-CoA reductase. ...
پلیفنل - ویکیپدیا، دانشنامهٔ آزاد
1978). Direct synthesis, structure and absolute configuration of biflavonoids from black wattle bark (mimosa) extract. J. Chem ...
List of MeSH codes (D03)
... biflavonoids MeSH D03.438.150.266.450.206 - catechin MeSH D03.438.150.266.450.221 - chalcones MeSH D03.438.150.266.450.221.500 ... biflavonoids MeSH D03.830.219.266.450.206 - catechin MeSH D03.830.219.266.450.221 - chalcones MeSH D03.830.219.266.450.221.500 ...
The biflavonoids 2",3"-dihydrohinokiflavone, 2,3,2",3"-tetrahydrohinokiflavone, 2,3-dihydroamentoflavone, 2,3,2",3"- ...
Molecules | Free Full-Text | Low-Density Lipoprotein (LDL)-Antioxidant Biflavonoids from Garcinia madruno
The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu2+, was studied ... The flavanone-(3→8)-flavone biflavonoids displayed antioxidant activity, particularly morelloflavone, which was significantly ... Six biflavonoids were isolated from G. madruno, one of which, 7-O-(6-acetyl)-glucoside of morelloflavone, is a new ... Six biflavonoids were isolated from G. madruno, one of which, 7-O-(6-acetyl)-glucoside of morelloflavone, is a new ...
IJMS | Free Full-Text | Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of ... Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of ... Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis. Li-Yin Chen 1,* , Ih-Sheng ... Chen L-Y, Chen I-S, Peng C-F. Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis ...
Natural biflavonoids as potential therapeutic agents against microbial diseases - PubMed
Natural biflavonoids as potential therapeutic agents against microbial diseases José C J M D S Menezes 1 , Vinícius R Campos 2 ... Natural biflavonoids as potential therapeutic agents against microbial diseases José C J M D S Menezes et al. Sci Total Environ ... Antiviral activities of biflavonoids. Lin YM, Flavin MT, Schure R, Chen FC, Sidwell R, Barnard DL, Huffman JH, Kern ER. Lin YM ... Biochemical pharmacology of biflavonoids: implications for anti-inflammatory action. Kim HP, Park H, Son KH, Chang HW, Kang SS. ...
Profile for - iHerb.com
Naturally occurring phenols - Wikipedia
Quantitative analysis of flavan-3-ols in Spanish foodstuffs and beverages
Lignophytes, and Cycadales in particular
Medical Herbalism The Science & Practice of Herbal Medicine: David Hoffmann: Hardcover: 9780892817498: Powell's Books
Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer | DR. NDAKALA...
Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer. ... and biflavonoids: chamaejasmin (3), 7,7″-di-O-methylchamaejasmin (4) and campylospermone A (5), a dimeric chromene [diphysin(6 ... "Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer." ...
In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania)...
S. sellowii may be a potential source of biflavonoids that could provide promising compounds for the treatment of cutaneous ... Animals , Female , Mice , Antiprotozoal Agents/therapeutic use , Biflavonoids/therapeutic use , Leishmania/drug effects , ... In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) ... In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella ...
Plant antitumor agents. 31. The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human...
The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines. ... The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines. Journal ... Three new biflavonoids to which we have accorded the trivial names calycopterone (1), isocalycopterone (2), and 4- ...
DNA topoisomerase inhibitors: biflavonoids from Ouratea species | Braz. j. med. biol. res;35(7): 819-822, July 2002. ilus |...
DNA topoisomerase inhibitors: biflavonoids from Ouratea species DNA topoisomerase inhibitors: biflavonoids from Ouratea species ... These biflavonoids and the acetyl derivative of II (IIa) are inhibitors of human DNA topoisomerases I at 200 æM, as ... These biflavonoids were assayed against human K562 leukemia cells in 45-h culture, but only I showed 42 percent growth ... The biflavonoids showed concentration-dependent growth inhibitory activities on Ehrlich carcinoma cells in 45-h culture, ...
The Flavonoids : Advances in Research since Nineteen Eighty by J. B. Harborne | 9780412287701 | Booktopia
Cycas revoluta - Wikipedia
Lonicera japonica - Wikipedia
Antioxidant activity and phenolic content of Oregon caneberries
Pentameric procyanidins isolated from Theobroma cacao seeds selectively downregulate ErbB2 in human aortic endothelial cells.
The Enzymology of Proanthocyanidin Biosynthesis | SpringerLink
Amentoflavone - Wikipedia
CiNii 論文 - S-Phase Accumulation of Candida albicans by Anticandidal Effect of Amentoflavone...
Braz J Med Biol Res - vol.35 issue7
KAKEN - Research Projects | The inventory of rare plants and these evaluation of both usefulness and safety by the utilization...
Presentation] Biflavonoids from the roots of Diplomorpha canescens. *. Author(s). Hari Prasad Devkota, Khem Raj Joshi, 渡邊高志, 矢原 ... Journal Article] Biflavonoids, Lignans and Related Compounds from the Roots of Diplomorpha canescens2015. *. Author(s). Hari ... Journal Article] Isolation, Structure Determination, and Anti-HIV Evaluation of Tigliane-Type Diterpenes and Biflavonoids from ...
Journal of the Brazilian Chemical Society
Joint Max TS (120 Soft Chews) | Free Shipping* | EntirelyPets
Frontiers | Metabolic Profile and Root Development of Hypericum perforatum L. In vitro Roots under Stress Conditions Due to...
Enhancement of Bioactive Compounds and Antioxidant Activities of Olive ( Olea europaea L.) Leaf Extract by Instant Controlled...
- Members of this family are characterised by the presence of flavonoids, biflavonoids and terpenoids as main secondary metabolites. (scielo.org.za)
- From Ormocarpum kirkii, a series of known flavonoids and biflavonoids was obtained, as well as three new compounds, i.e., 7,7′′-di-O-β-D-glucosyl-(−)-chamaejasmin, 7-O-β-D-glucosyl-(I-3,II-3)-biliquiritigenin, and isovitexin-(I-3,II-3)-naringenin. (sigmaaldrich.com)
- It contains flavonoids (flavonol glycoside and non-glycosidid biflavonoids), unique diterpene lactones (gingolides A, B, C, J and M) as well as a sesquiterpenoid (bilobalide). (ageless.co.za)
- This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from this plant (SSHE), as well as of the biflavonoids amentoflavone and robustaflavone, isolated from this species. (bvsalud.org)
- 7"-O-Methyl-agathisflavone (I) and amentoflavone (II) are biflavonoids and were isolated from the Brazilian plants Ouratea hexasperma and O. semiserrata, respectively. (bvsalud.org)
- Amentoflavone is one of the plant-derived biflavonoids currently being explored for potent pharmacological activities. (alliedacademies.org)
- This compound belongs to the class of organic compounds known as biflavonoids and polyflavonoids. (hmdb.ca)
- Benzophenones are the major secondary metabolites in G. gummi-gutta, followed by xanthones and biflavonoids. (healthbenefitstimes.com)
- Previous activity-guided phytochemical studies on Garcinia buchananii stem bark, which is traditionally used in Africa to treat various gastrointestinal and metabolic illnesses, revealed xanthones, polyisoprenylated benzophenones, flavanone-C-glycosides, biflavonoids, and/or biflavanones as bioactive key molecules. (tum.de)
- Adem FA, Mbaveng AT, Kuete V, Heydenreich M, Ndakala A, Irungu B, Yenesew A, Efferth T. "Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer. (ac.ke)
- The aim of this study was to determine the cytotoxicity of isoflavones: osajin (1), 5,7-dihydroxy-4ˈ-methoxy-6,8-diprenylisoflavone (2) and biflavonoids: chamaejasmin (3), 7,7″-di-O-methylchamaejasmin (4) and campylospermone A (5), a dimeric chromene [diphysin(6)] and an ester of ferullic acid with long alkyl chain [erythrinasinate (7)] isolated from the stem bark and roots of the Kenyan medicinal plant, Ormocarpum kirkii. (ac.ke)
- 31. The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines. (duke.edu)
- Three new biflavonoids to which we have accorded the trivial names calycopterone (1), isocalycopterone (2), and 4-demethylcalycopterone (3) and the known flavone 4',5-dihydroxy-3,3',6,7-tetramethoxyflavone (4) were isolated as cytotoxic constituents from the flowers of Calycopteris floribunda Lamk. (duke.edu)
- Roots yielded biflavonoids and sterols. (stuartxchange.com)
- Unequivocal structure elucidation of biflavonoids and biflavanones by means of NMR spectroscopy is often complicated by the hindered rotation of the monomers around the C-C axis (atropisomerism), resulting in a high spectral complexity. (tum.de)
- Osorio E, Londoño J, Bastida J. Low-Density Lipoprotein (LDL)-Antioxidant Biflavonoids from Garcinia madruno . (mdpi.com)
- Recent reports have shown that synthetic biflavonoids are now produced for specific therapeutic uses [ 6 ]. (alliedacademies.org)
- Six biflavonoids were isolated from G. madruno , one of which, 7''- O -(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. (mdpi.com)
- The flavanone-(3→8'')-flavone biflavonoids displayed antioxidant activity, particularly morelloflavone, which was significantly more potent than quercetin, with a CE 50 of 12.36 μg/mL. (mdpi.com)
- Approximately 109 phytochemical constituents have been searched out as isolates from various parts of this plant comprising mostly diterpenoids and biflavonoids. (eurekaselect.com)
- Biflavonoids are generally known for a wide number of pharmacological potentials in different countries and they are found in limited number of plants with interesting medicinal and pharmacological properties. (alliedacademies.org)
- Stafford, H.A. Enzymic regulation of procyanidin biosynthesis: lack of flav-3-en-3-ol intermediate. (springer.com)
- Three new biflavonoids, wikstaiwanones A-C ( 1 - 3 ), along with four known compounds ( 4 - 7 ) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). (mdpi.com)
- S. sellowii may be a potential source of biflavonoids that could provide promising compounds for the treatment of cutaneous leishmaniasis . (bvsalud.org)
- Biflavonoids are unique biologically active naturally-occurring compounds for which the attentions of researchers have been drawn over the years. (alliedacademies.org)
- The two biflavonoids, 3′-O-methyl loniflavone and loniflavone, along with luteolin and chrysin, can be isolated from the leaves. (wikipedia.org)
- The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu 2+ , was studied by means of a TBARS assay. (mdpi.com)
- These biflavonoids were assayed against human K562 leukemia cells in 45-h culture, but only I showed 42 percent growth inhibitory activity at 90 æM. (bvsalud.org)
- The biflavonoids showed concentration-dependent growth inhibitory activities on Ehrlich carcinoma cells in 45-h culture, assayed by a tetrazolium method, with IC50 = 24 ± 1.4 æM for I, 26 ± 1.1 æM for II and 10 ± 0.7 æM for IIa. (bvsalud.org)
- Anti-virulence activities of biflavonoids from Mesua ferrea L. flower. (nih.gov)
- These biflavonoids and the acetyl derivative of II (IIa) are inhibitors of human DNA topoisomerases I at 200 æM, as demonstrated by the relaxation assay of supercoiled DNA, and only agathisflavone (I) at 200 æM also inhibited DNA topoisomerases II-alpha, as observed by decatenation and relaxation assays. (bvsalud.org)
- However, the connecting linkages are present at diverse positions yielding more than a hundred biflavonoids which have been isolated and structurally characterized till date [ 1 , 5 ]. (alliedacademies.org)
- Kennelly, E. J. - Benzophenones and Biflavonoids from Garcinia livingstonei Fruits, J. Agric. (ac.vn)
- The result suggests that these biflavonoids maybe potential as insulin mimetics for developing antidiabetic agents. (ac.vn)