Dimers (homo and hetero) of FLAVONOIDS.
A plant genus of the family CLUSIACEAE. Members contain XANTHONES.
A plant genus of the family THYMELAEACEAE. They are evergreen shrubs much cultivated in garden borders and rock gardens in mild climates. Members contain mezerein, flavonoids, and COUMARINS such as daphnetin and daphnin.
A plant genus of the family Cycadaceae, order Cycadales, class Cycadopsida, division CYCADOPHYTA of palm-like trees. It is a source of CYCASIN, the beta-D-glucoside of methylazoxymethanol.
Attachment of isoprenoids (TERPENES) to other compounds, especially PROTEINS and FLAVONOIDS.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A group of phenyl benzopyrans named for having structures like FLAVONES.
A plant genus of the family THYMELAEACEAE. Members contain daphnoretin and wikstroelides and daphnane-type DITERPENES.
SESQUITERPENES cyclized into two adjoining rings, one being 7-carbons and the other is 5-carbons.
A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mainly trees and shrubs. Many members contain mucilage and COUMARINS.
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.
The infusion of leaves of CAMELLIA SINENSIS (formerly Thea sinensis) as a beverage, the familiar Asian tea, which contains CATECHIN (especially epigallocatechin gallate) and CAFFEINE.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.
A plant family of the order Nepenthales.
The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS.
Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.
Presence of warmth or heat or a temperature notably higher than an accustomed norm.
Organic matter in a state of advanced decay, after passing through the stages of COMPOST and PEAT and before becoming lignite (COAL). It is composed of a heterogenous mixture of compounds including phenolic radicals and acids that polymerize and are not easily separated nor analyzed. (E.A. Ghabbour & G. Davies, eds. Humic Substances, 2001).
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Large aggregates of CELESTIAL STARS; COSMIC DUST; and gas. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)
An antiseptic and disinfectant aromatic alcohol.
A frozen dairy food made from cream or butterfat, milk, sugar, and flavorings. Frozen custard and French-type ice creams also contain eggs.
Large bodies consisting of self-luminous gas held together by their own gravity. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)
A tree of the family Sterculiaceae (or Byttneriaceae), usually Theobroma cacao, or its seeds, which after fermentation and roasting, yield cocoa and chocolate.
Dimers and oligomers of flavan-3-ol units (CATECHIN analogs) linked mainly through C4 to C8 bonds to leucoanthocyanidins. They are structurally similar to ANTHOCYANINS but are the result of a different fork in biosynthetic pathways.
A group of 3-hydroxy-4-keto-FLAVONOIDS.
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
Measurement and evaluation of the components of substances to be taken as FOOD.
A division of GYMNOSPERMS which look like palm trees (ARECACEAE) but are more closely related to PINUS. They have large cones and large pinnate leaves and are sometimes called cycads, a term which may also refer more narrowly to cycadales or CYCAS.
A plant family of the order Pinales, class Pinopsida, division Coniferophyta (conifers). They are mainly resinous, aromatic evergreen trees.
Seedless nonflowering plants of the class Filicinae. They reproduce by spores that appear as dots on the underside of feathery fronds. In earlier classifications the Pteridophyta included the club mosses, horsetails, ferns, and various fossil groups. In more recent classifications, pteridophytes and spermatophytes (seed-bearing plants) are classified in the Subkingdom Tracheobionta (also known as Tracheophyta).
Gymnosperms are a group of vascular plants whose seeds are not enclosed by a ripened ovary (fruit), in contrast to ANGIOSPERMS whose seeds are surrounded by an ovary wall. The seeds of many gymnosperms (literally, "naked seed") are borne in cones and are not visible. Taxonomists now recognize four distinct divisions of extant gymnospermous plants (CONIFEROPHYTA; CYCADOPHYTA; GINKGOPHYTA; and GNETOPHYTA).
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
A plant division. They are simple plants that lack vascular tissue and possess rudimentary rootlike organs (rhizoids). Like MOSSES, liverworts have alternation of generations between haploid gamete-bearing forms (gametophytes) and diploid spore-bearing forms (sporophytes).
The act of feeding on plants by animals.
The rose plant family in the order ROSALES and class Magnoliopsida. They are generally woody plants. A number of the species of this family contain cyanogenic compounds.
A species of baboon in the family CERCOPITHECIDAE found in southern Africa. They are dark colored and have a variable social structure.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
A plant genus of the family EBENACEAE, order Ebenales, subclass Dilleniidae, class Magnoliopsida best known for the edible fruit and the antibacterial activity and compounds of the wood.
A group of FLAVONOIDS derived from FLAVONOLS, which lack the ketone oxygen at the 4-position. They are glycosylated versions of cyanidin, pelargonidin or delphinidin. The conjugated bonds result in blue, red, and purple colors in flowers of plants.
Exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.
The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.
A plant genus of the family CUPRESSACEAE which should not be confused with other cedar and cypress trees of THUJA or CUPRESSUS genera.
A plant family of the order Selaginellales, class Lycopodiopsida, division Lycopodiophyta, subkingdom Tracheobionta. Members contain bilobetin. The rarely used common name of resurrection plant is mainly used with CRATEROSTIGMA.
Genus of perennial plants in the family CLUSIACEAE (sometimes classified as Hypericaceae). Herbal and homeopathic preparations are used for depression, neuralgias, and a variety of other conditions. Hypericum contains flavonoids; GLYCOSIDES; mucilage, TANNINS; volatile oils (OILS, ESSENTIAL), hypericin and hyperforin.
The only specie of the genus Ginkgo, family Ginkgoacea. It is the source of extracts of medicinal interest, especially Egb 761. Ginkgo may refer to the genus or species.
A plant family of the order Taxales, class Pinopsida, division CONIFEROPHYTA.
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.

Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. (1/171)

We have previously reported that proanthocyanidins extracted from grape seeds possess growth-promoting activity toward murine hair epithelial cells in vitro and stimulate anagen induction in hair cycle progression in vivo. This report constitutes a comparison of the growth-promoting activity of procyanidin oligomers and the target cells of procyanidins in the skin. Results show that procyanidin dimer and trimer exhibit higher growth-promoting activity than the monomer. The maximum growth-promoting activity for hair epithelial cells with procyanidin B-2, an epicatechin dimer, reached about 300% (30 microM) relative to controls (= 100%) in a 5 d culture. Optimum concentration of procyanidin C-1, an epicatechin trimer, was lower than that of procyanidin B-2; the maximum growth-promoting activity of procyanidin C-1 was about 220% (3 microM). No other flavonoid compounds examined exhibit higher proliferative activities than the procyanidins. In skin constituent cells, only epithelial cells such as hair keratinocytes or epidermal keratinocytes respond to procyanidin oligomers. Topical application of 1% procyanidin oligomers on shaven C3H mice in the telogen phase led to significant hair regeneration [procyanidin B-2, 69.6% +/- 21.8% (mean +/- SD); procyanidin B-3, 80.9% +/- 13.0%; procyanidin C-1, 78.3% +/- 7.6%] on the basis of the shaven area; application of vehicle only led to regeneration of 41.7% (SD = 16.3%). In this paper, we demonstrate the hair-growing activity of procyanidin oligomers both in vitro and in vivo, and their potential for use as agents to induce hair growth.  (+info)

Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. (2/171)

Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this study, we examined the inhibitory effects of black tea polyphenols, including theaflavin (TF-1), a mixture (TF-2) of theaflavin-3-gallate (TF-2a) and theaflavin-3'-gallate (TF-2b), theaflavin-3,3'-digallate (TF-3) and the thearubigin fraction on the autophosphorylation of the EGF and PDGF receptors in A431 cells and mouse NIH3T3 fibroblast cells, respectively. First, we examined the effects of these polyphenols on the proliferation of A431 and NIH3T3 cells. Both EGCG and TF-3 strongly inhibited the proliferation of A431 and NIH3T3 cells more than the other theaflavins did. In cultured cells with pre-treatment of tea polyphenol, TF-3 was stronger than EGCG on the reduction of EGF receptor and PDGF receptor autophosphorylation induced by EGF and PDGF, respectively. Other theaflavins slightly reduced the autophosphorylation of the EGF and PDGF receptors; furthermore, TF-3 could reduce autophosphorylation of the EGF receptor (or PDGF receptor) even with co-treatment with EGF (or PDGF) and TF-3, but EGCG was inactive under these conditions. In addition, TF-3 was stronger than EGCG in blocking EGF binding to its receptor. These results suggest that not only the green tea polyphenol, EGCG, but also the black tea polyphenol, TF-3, have an antiproliferative activity on tumor cells, and the molecular mechanisms of antiproliferation may block the growth factor binding to its receptor and thus suppress mitogenic signal transduction.  (+info)

Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. (3/171)

Procyanidins present in grape seeds are known to exert anti-inflammatory, anti-arthritic and anti-allergic activities, prevent skin aging, scavenge oxygen free radicals and inhibit UV radiation-induced peroxidation activity. Since most of these events are associated with the tumor promotion stage of carcinogenesis, these studies suggest that grape seed polyphenols and the procyanidins present therein could be anticarcinogenic and/or anti-tumor-promoting agents. Therefore, we assessed the anti-tumor-promoting effect of a polyphenolic fraction isolated from grape seeds (GSP) employing the 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol 13-acetate (TPA)-promoted SENCAR mouse skin two-stage carcinogenesis protocol as a model system. Following tumor initiation with DMBA, topical application of GSP at doses of 0.5 and 1.5 mg/mouse/application to the dorsal initiated mouse skin resulted in a highly significant inhibition of TPA tumor promotion. The observed anti-tumor-promoting effects of GSP were dose dependent and were evident in terms of a reduction in tumor incidence (35 and 60% inhibition), tumor multiplicity (61 and 83% inhibition) and tumor volume (67 and 87% inhibition) at both 0.5 and 1.5 mg GSP, respectively. Based on these results, we directed our efforts to separate and identify the individual polyphenols present in GSP and assess their antioxidant activity in terms of inhibition of epidermal lipid peroxidation. Employing HPLC followed by comparison with authentic standards for retention times in HPLC profiles, physiochemical properties and spectral analysis, nine individual polyphenols were identified as catechin, epicatechin, procyanidins B1-B5 and C1 and procyanidin B5-3'-gallate. Five of these individual polyphenols with evident structural differences, namely catechin, procyanidin B2, procyanidin B5, procyanidin C1 and procyanidin B5-3'-gallate, were assessed for antioxidant activity. All of them significantly inhibited epidermal lipid peroxidation, albeit to different levels. A structure-activity relationship study showed that with an increase in the degree of polymerization in polyphenol structure, the inhibitory potential towards lipid peroxidation increased. In addition, the position of linkage between inter-flavan units also influences lipid peroxidation activity; procyanidin isomers with a 4-6 linkage showed stronger inhibitory activity than isomers with a 4-8 linkage. A sharp increase in the inhibition of epidermal lipid peroxidation was also evident when a gallate group was linked at the 3'-hydroxy position of a procyanidin dimer. Procyanidin B5-3'-gallate showed the most potent antioxidant activity with an IC(50) of 20 microM in an epidermal lipid peroxidation assay. Taken together, for the first time these results show that grape seed polyphenols possess high anti-tumor-promoting activity due to the strong antioxidant effect of procyanidins present therein. In summary, grape seed polyphenols in general, and procyanidin B5-3'-gallate in particular, should be studied in more detail to be developed as cancer chemopreventive and/or anticarcinogenic agents.  (+info)

Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved. (4/171)

ras gene mutation, which perpetually turns on the growth signal transduction pathway, occurs frequently in many cancer types. The mouse epidermal JB6 cell line has been transfected with a mutant H-ras gene to mimic carcinogenesis in vitro. These transformed cells (30.7b Ras 12) are able to grow in soft agar, exhibiting anchorage independence and high endogenous activator protein 1 (AP-1) activity, which can be detected by a stable AP-1 luciferase reporter. The present study investigated the ability of different pure green and black tea polyphenols to inhibit this ras signaling pathway. The major green tea polyphenols (catechins), (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin, (-)-epicatechin-3-gallate, (-)-epicatechin, and their epimers, and black tea polyphenols, theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate (TFdiG), were compared with respect to their ability to inhibit the growth of 30.7b Ras 12 cells and AP-1 activity. All of the tea polyphenols except (-)-epicatechin showed strong inhibition of cell growth and AP-1 activity. Among the catechins, both the galloyl structure on the B ring and the gallate moiety contributed to the growth inhibition and AP-1 activity; the galloyl structure appeared to have a stronger effect on the inhibitory action than the gallate moiety. The epimers of the catechins showed similar inhibitory effects on AP-1 activity. The addition of catalase to the incubation of the cells with EGCG or TFdiG did not prevent the inhibitory effect on AP-1 activity, suggesting that H2O2 does not play a significant role in the inhibition by tea polyphenols. Both EGCG and TFdiG inhibited the phosphorylation of p44/42 (extracellular signal-regulated kinase 1 and 2) and c-jun without affecting the levels of phosphorylated-c-jun-NH2-terminal kinase. TFdiG inhibited the phosphorylation of p38, but EGCG did not. EGCG lowered the level of c-jun, whereas TFdiG decreased the level of fra-1. These results suggest that tea polyphenols inhibited AP-1 activity and the mitogen-activated protein kinase pathway, which contributed to the growth inhibition; however, different mechanisms may be involved in the inhibition by catechins and theaflavins.  (+info)

Protection against peroxynitrite by cocoa polyphenol oligomers. (5/171)

Flavonoids, natural plant constituents, protect against peroxynitrite and can thereby play a role in defense against this mediator of inflammation. Procyanidin oligomers of different size (monomer through nonamer), isolated from the seeds of Theobroma cacao, were examined for their ability to protect against peroxynitrite-dependent oxidation of dihydrorhodamine 123 and nitration of tyrosine. By molarity, oligomers were more effective than the monomeric epicatechin; the tetramer was particularly efficient at protecting against oxidation and nitration reactions. These results suggest that epicatechin oligomers found in cocoa powder and chocolate may be a potent dietary source for defense against peroxynitrite.  (+info)

Procyanidin content and variation in some commonly consumed foods. (6/171)

Procyanidins are a subclass of flavonoids found in commonly consumed foods that have attracted increasing attention due to their potential health benefits. However, little is known regarding their dietary intake levels because detailed quantitative information on the procyanidin profiles present in many food products is lacking. Therefore, the procyanidin content of red wine, chocolate, cranberry juice and four varieties of apples has been determined. On average, chocolate and apples contained the largest procyanidin content per serving (164.7 and 147.1 mg, respectively) compared with red wine and cranberry juice (22.0 and 31.9 mg, respectively). However, the procyanidin content varied greatly between apple samples (12.3-252.4 mg/serving) with the highest amounts on average observed for the Red Delicious (207.7 mg/serving) and Granny Smith (183.3 mg/serving) varieties and the lowest amounts in the Golden Delicious (92.5 mg/serving) and McIntosh (105.0 mg/serving) varieties. The compositional data reported herein are important for the initial understanding of which foods contribute most to the dietary intake of procyanidins and may be used to compile a database necessary to infer epidemiological relationships to health and disease.  (+info)

Cocoa procyanidins and human cytokine transcription and secretion. (7/171)

We examined whether cocoa, in its isolated procyanidin fractions (monomer through decamer), would modulate cytokine production at the levels of transcription and protein secretion in both resting and phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMC). In resting cells, interleukin (IL)-1beta and IL-4 gene expression from cocoa-treated cells varied markedly among the subjects tested. However, at the protein level, the larger fractions (pentamer through decamer) stimulated a dramatic increase in IL-1beta concentration (up to ninefold) with increasing degree of polymerization. Similarly, these larger fractions augmented IL-4 concentration by as much as 2 pg/ml, whereas the control displayed levels nearly undetectable. In the presence of PHA, gene expression also seemed to be most affected by the larger procyanidin fractions. The pentameric through decameric fractions increased IL-1 beta expression by 7-19% compared with PHA control, whereas the hexameric through decameric fractions significantly inhibited PHA-induced IL-4 transcription in the range of 71-86%. This observation at the transcription level for IL-1 beta was reflected at the protein level in PHA-stimulated PBMC. Significant reductions in mitogen-induced IL-4 production were also seen at the protein level with the hexamer, heptamer and octamer. Individual oligomeric cocoa fractions were unstimulatory for IL-2 in resting PBMC. However, when induced with PHA, the pentamer, hexamer and heptamer fractions caused a 61-73% inhibition in IL-2 gene expression. This study offers additional data for the consideration of the health benefits of dietary polyphenols from a wide variety of foods, including those benefits associated specifically with cocoa and chocolate consumption.  (+info)

Reactions of peroxynitrite with cocoa procyanidin oligomers. (8/171)

Peroxynitrite is a mediator molecule in inflammation, and its biological properties are being studied extensively. Flavonoids, which are natural plant constituents, protect against peroxynitrite and thereby could play an anti-inflammatory role. Procyanidin oligomers of different sizes (monomer through nonamer), isolated from the seeds of Theobroma cacao, were recently examined for their ability to protect against peroxynitrite-dependent oxidation of dihydrorhodamine 123 and nitration of tyrosine and were found to be effective in attenuating these reactions. The tetramer was particularly efficient at protecting against oxidation and nitration reactions. Epicatechin oligomers found in cocoa powder and chocolate may be a potent dietary source for defense against peroxynitrite.  (+info)

PMID: Clin Interv Aging. 2012 ;7:275-86. Epub 2012 Jul 27. PMID: 22956863. Abstract Title: Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin. Abstract: BACKGROUND: French maritime pine bark extract (PBE) has gained popularity as a dietary supplement in the treatment of various diseases due to its polyphenol-rich ingredients. Oligometric proanthocyanidins (OPCs), a class of bioflavonoid complexes, are enriched in French maritime PBE and have antioxidant and anti-inflammatory activity. Previous studies have suggested that French maritime PBE helps reduce ultraviolet radiation damage to the skin and may protect human facial skin from symptoms of photoaging. To evaluate the clinical efficacy of French maritime PBE in the improvement of photodamaged facial skin, we conducted a randomized trial of oral supplementation with PBE.METHODS: One hundred and twelve women with mild to moderate photoaging of the skin were randomized ...
French Maritime Pine Bark Extract, also simply known as pine bark extract and marketed under the trade name Pycnogenol, is a medicinal substance derived...
In this study a new capillary electrophoresis (CE) method was developed to quantify the four major theaflavins occurring in black tea. Where aqueous based CE methods showed poor selectivity and considerable band broadening, non-aqueous CE achieved baseline separation of the theaflavins within 10 min. The effects of the organic solvent composition and background electrolyte concentration on the separation selectivity and electrophoretic mobilities were investigated. Our optimized separation solution consisted of acetonitrile-methanol-acetic acid (71:25:4, v/v) and 90 mM ammonium acetate. This method was used to analyze three black tea samples.
ArthroMax with Theaflavins & AprèsFlex 120 vegetarian capsuleAs people grow older, age-related stiffness and discomfort in the joints becomes a fact of life. Activities once routine become a challenge as limited mobility hampers your every move. You now have a more potent option to provide broad-spectrum support for aging joints. ArthroMax is available with Black Tea Theaflavins (without UC-II) to protect against immune attack in the joints via a separate mechanism. Inflammatory reactions are regulated by a series of cytokines produced in the body. Normal aging results in an unfavorable balance of these cytokines that contributes to persistent inflammatory conditions. Studies have shown that a special fraction found in black tea suppresses proinflammatory cytokines at the genomic level. Scientists have found that these com-pounds called theaflavins uniquely downregulate the expression of genes and cytokines associated with inflammatory conditions. ArthroMax with Theaflavins and AprèsFlex
Brain inflammation is one of the main causes of epileptogenesis, a chronic process triggered by various insults, including genetic or acquired factors that enhance susceptibility to seizures. Amentoflavone, a naturally occurring biflavonoid compound that has anti-inflammatory effects, exerts neuroprotective effects against nervous system diseases. In the present study, we aimed to investigate the effects of amentoflavone on epilepsy in vivo and in vitro and elucidate the underlying mechanism. The chronic epilepsy model and BV2 microglial cellular inflammation model were established by pentylenetetrazole (PTZ) kindling or lipopolysaccharide (LPS) stimulation. Cognitive dysfunction was tested by Morris water maze while hippocampal neuronal apoptosis was evaluated by immunofluorescence staining. The levels of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome complexes and inflammatory cytokines were determined using quantitative real-time polymerase chain reaction, Western
The biflavonoid amentoflavone was identified in research as an antagonist of the very same receptor. I would like to know whether a Ginkgo Biloba-leaf extract may contain a significant amount of amentoflavone.
There is much evidence showing that PYC has beneficial effects on physiological functions. Results from ongoing clinical research are required to confirm and extend previous observations.
ArthroMAX with Theaflavin & AprsFlex Not to be sold in Belgium 120 VegCapProduct DescriptionArthroMax R with Theaflavins & AprsFlex R is one of our ArthroMax R family of joint supplements. It combines five innovative nutrients to support joint and connective tissue health and mobility.Black tea theaflavins, MSM
In recent decade, Hyperlipidemia related disorders like obesity, hypercholesterolemia and diabetes are considered as the leading killers for mankind. Fundamental nexus between nutrition and health diverting the consumers focus towards plant based natural products as a remedy against various metabolic syndrome. Considering this, present study was conducted to explicate the role of black tea polyphenols such as Theaflavins and thearubigins therapeutic potential to tackle targeted maladies especially oxidative stress related disorders like hypercholesterolemia and diabetes. The mandate of current investigation was to explore the hypoglycemic and hypocholestrolemic perspective of isolated theaflavin and thearubigins through a model feeding trial. For the purpose, theaflavin & thearubigins were isolated from black tea through solvent partition method and utilize to form three types of nutraceutical drinks (theaflavin, thearubigins & theaflavin + thearubigins based) alongside control to be further utilized in
Extracts from French maritime pine bark may protect against heart failure, if a new study with mice can be translated into humans.
Insights into interaction profile and inhibitory potential of amentoflavone with ?-glucosidase, tyrosinase and 15-lipoxygenase as validated therapeutic targets., Tomisin Happy Ogun
October 2010 Journal Panminerva Medica, • Daily supplements of French maritime pine bark extract (Pycnogenol) may ease tinnitus. • It may improve blood flow to the inner ear and therefore relieve tinnitus symptoms.. •Impaired blood flow to the ear is a common cause for tinnitus. Patients should try 100 to 150 milligrams per day of Pycnogenol (pine bark). Order @ www.DrJeffreyTucker.meta-ehealth.com •Pycnogenol is effective in a short period of time in relieving tinnitus symptoms by improving cochlear blood flow.. Panminerva Medica 52(2 Suppl 1):63-68, 2010. More ...
Pycnogenol®, the French maritime pine bark extract, may improve the symptoms of erectile dysfunction and improve circulation and blood flow, which strengthens the vascular system and manages cholesterol.
Theasinensin A is one of the oolong tea theasinensins, which differ from green tea catechins and black tea theaflavins. In a previous study, we found that theasinesin A had a potential effect on antiinflammation since theasinensin A suppressed LPS-induced COX2 and PGE(2) production. To clarify the molecular mechanisms, we investigated the gene expression profiling in macrophage-like cells treated with theasinensin A through a genome-wide DNA microarray in the present study. Among 22,050 oligonucleotides, the expression levels of 406 genes were increased by ≥3-fold in LPS-activated RAW264 cells, 259 gene signals of which were attenuated by theasinensin A treatment (≥2-fold). Expression levels of 717 genes were decreased by ≥3-fold in LPS-activated cells, of which 471 gene signals were restored by theasinensin A treatment (≥2-fold). These genes were further categorized as defense, inflammatory response, cytokines activities, and receptor activities, and some of them were confirmed by ...
Bloggers note: You may have read a number of references or seen a number of websites for ADHD and multiple other ailments touting the benefits of compounds such as pycnogenol (also known as French Maritime Pine Bark Extract), and grape-seed extract. As of now, I am neutral as far as using products such as these. However, it is important to note that the majority of the benefits derived from treatments such as these are due to their antioxidant effects, which are quite powerful by the way (however, other functions besides mere antioxidant effects have been suggested and are entirely possible). Additionally, these supplements can be quite costly. It is this bloggers opinion that similar effects and benefits can be seen with vitamin C and E supplementation for a cheaper price. Nonetheless, the large number of studies supporting the effectiveness of pycnogenol and grape-seed extract does warrant further investigation and potential success as an ADHD treatment option. With youre doctors ...
Dimeric procyanidin B2 (PB2) is one of phenolic compounds in apple pomace, an agro-industrial byproduct in apple juice processing. This work focused on purification of PB2 from apple pomace using sephadex column chromatography and its potential effect on lipopolysaccharide (LPS)-induced inflammation using RAW264.7 macrophages. PB2 with the purity of 72.28 ± 1.85% was successfully afforded using resin and gel column chromatographic technique. Anti-inflammatory tests suggested that the expression of cyclooxygenase-2 (COX-2) in LPS-induced murine RAW264.7 macrophages was suppressed in a PB2 concentration-dependent manner. PB2 at no less than 50 µg mL-1 could significantly suppress inflammation in the LPS-induced cells. Moreover, this suppressive effect was not correlated with PB2 pretreating. However, the COX-2 expression was not reduced in LPS pretreatment way followed by PB2 exposure, which suggested that PB2 has no repairing function. The results showed that high pure PB2 prepared from ...
|p|This premium French maritime pine bark extract contains numerous bioactive compounds that support capillary and connective tissue function and provide antioxidant protection.|sup|†|/sup| Pycnogenol|sup|®|/sup| is a powerful scavenger of free radicals i
Procyanidin B2 improves oocyte maturation and subsequent development in Type 1 diabetic mice by promoting mitochondrial function.
Sigma-Aldrich offers abstracts and full-text articles by [Stavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J King, Jonathan E Brown, Michael N Clifford].
Theaflavin Standardized Extract contains a number of beneficial flavonoids found naturally in tea leaves that help support levels of cholesterol that are already within the normal range.
Rapid determination of theaflavins by HPLC with a new monolithic column | Jianyong Zhang, Hongchun Cui, Heyuan Jiang, Lei Fang, Weiwei Wang, Wei Su, Chunhua Xiong | Agricultural Journals
Sigma-Aldrich offers abstracts and full-text articles by [Dandan Li, Tingbao Zhao, Jianzhong Meng, Ying Jing, Fengyu Jia, Ping He].
Originally Posted by AZMIDLYF What ingredient is providing the pump? Amentoflavone. Also Im pretty sure this was designed to be used with NO Uptake.
4-Beta-D-glucoside, arbre dor (French), bioflavonoid, borovice hvezdicovit (Czech), caffeic acid, catechin, condensed tannins, epicatechin, ferulic acid, Flavangenol , free glucose, French maritime pine bark extract, French Pinus maritime bark, gallic acid, L-(feruloyl)-beta-D-glucose, L-(p-coumaroyl)-beta-D-glucose, maritime pine tree bark, merim nd (Estonian), oligomeric proanthocyanidin complexes, OPCs, PCOs, p-coumaric acid, phenolcarbonic acids, phenolic acids, phenolic fruit acid, p-hydroxybenzoic acid, pi mar tim (Catalan), pi pinastre (Catalan), pin de Bordeaux (French), pin de Corte (French), pin des Landes (French), pin maritime (French), pin m sog en (French), Pinaceae (family), pinastro (Italian, Spanish), pinheiro-bravo (Portuguese), pino costiero (Italian), pino gallego (Spanish), pino mar timo (Spanish), pino marittimo (Italian), pino resinero (Spanish), pino rodeno (Spanish), pino rubial (Spanish), Pinus pinaster, Pinus maritima, polyphenols, proanthocyanidins, procyanidins, ...
Amentoflavone is a biflavonoid (bis-apigenin coupled at 8 and 3 positions, or 3′,8′′-biapigenin) constituent of a number of plants including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Hypericum perforatum (St. Johns Wort) and Xerophyta plicata. Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body. It is also an inhibitor of human cathepsin B. Amentoflavone has a variety of in vitro activities including antimalarial activity, anticancer activity (which may, at least in part, be mediated by its inhibition of fatty acid synthase), and antagonist activity at the κ-opioid receptor (Ke = 490 nmol L−1) as well as activity at the allosteric benzodiazepine site of the GABAA receptor as a negative allosteric modulator. Apigenin Pan X, Tan N, Zeng G, Zhang Y, Jia R (2005). Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B. Bioorg. Med. ...
Amentoflavone, which is a biflavone derived from various plants, has been known to possess various biological activities including anti-tumor and anti-inflammatory activity. In the previous study, we reported antifungal effect of amentoflavone isolated from an ethyl acetate extract of Selaginella tamariscina on human pathogenic fungi. Amentoflavone significantly inhibited the growth of fungal cells without hemolysis of human erythrocytes. In the present study, we investigated antifungal acting mode of amentoflavone in human pathogenic yeast Candida albicans. Anticandidal activity was exerted in an energy-independent manner presented by an antifungal assay in the presence of NaN3, which is ATP-depleting agent as a metabolic inhibitor. To investigate the effects of amentoflavone on cellular physiology in C. albicans, we performed cell cycle analysis, and the analysis showed that amentoflavone significantly arrested cell cycles during the S-phase. These results demonstrated that amentoflavone has ...
Grape seed procyanidin extract may represent a new therapeutical direction for the treatment of ischemia-reperfusion brain injury.
Pycnogenol® reduced skin wrinkles by three percent and increased skin smoothness by six percent. To date, Pycnogenol® is the only natural supplement that stimulates hyaluronic acid production in human skin. And, we are encouraged by the molecular evidence confirmed in this study that shows nutritional supplementation with Pycnogenol® benefits human skin, explains Dr. Jean Krutmann, the lead researcher from the Leibniz Research Institute in Dusseldorf, Germany.. Study results confirmed Pycnogenol® improved skin at a physiological and molecular level. Pycnogenol® increased hyaluronic acid in women by 44 percent after 12 weeks of supplementation. Hyaluronic acid binds large quantities of water in the skin and in other tissues, such as cartilage. An increased amount of hyaluronic acid explains the increased skin hydration, higher elasticity and overall smoother skin appearance found in women taking Pycnogenol®.. This exciting and technically advanced investigation with women representing ...
Flavanols and their oligomeric derivatives, the procyanidins, are plant-derived compounds normally present in the human diet. Accumulating data demonstrate a causal role for flavanols in mediating the cardiovascular benefits associated with the consumption of flavanol-/procyanidin-containing foods. Evidence for a direct, causal role for procyanidins in this context is far less profound. As this is often based on the poor absorption of procyanidins, it has been proposed that procyanidins may indirectly contribute to the systemic presence of bioactive compounds via derivatives generated from the breakdown or catabolism of procyanidins in the gastrointestinal tract. These postulated breakdown products include: i) flavanols, putatively generated by acid hydrolysis in the stomach, and ii) series of phenolic compounds, including 5-(3,4-dihydroxyphenyl)-gamma-valerolactone, that are produced from procyanidin catabolism by the gut microbiome. Verification or rejection of these suppositions could ...
French maritime pine bark extract (Pycnogenol®) displays a variety of anti-inflammatory effects in vivo. Aim of this study was to determine whether human plasma after oral intake of Pycnogenol...
Selaginella tamariscina is an evergreen Perennial growing to 0.1 m (0ft 4in). It is in leaf 12-Jan. The flowers are hermaphrodite (have both male and female organs)Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Suitable pH: acid, neutral and basic (alkaline) soils. It can grow in semi-shade (light woodland). It prefers moist soil.
Proanthocyanidins, also known as condensed tannins and/or oligomeric flavonoids, occur in many edible plants and have various interesting biological activities. Previously, we reported a synthetic method for the preparation of various procyanidins in pure form and described their biological activities. Here, we describe the synthesis of procyanidin B1 acetylated analogs and discuss their inhibition activities against HeLa S3 cell proliferation. Surprisingly, the lower-unit acetylated procyanidin B1 strongly inhibited the proliferation of HeLa S3 cells. This molecule showed much stronger inhibitory activity than did epigallocatechin-3-O-gallate (EGCG), green tea polyphenol, and dimeric compounds that included EGCG as a unit. This result suggests that the phenolic hydroxyl groups of the upper-units in flavan-3-ols are important for their inhibitory activity against cancer cell proliferation and that a hydrophobic lower unit dimer enhances this activity.
0046]Milling step can be carried out at temperatures from 0° C. to 30° C. When the mixture was milled with a mixer for 3 minutes, the content of the theaflavins was substantially increased over that from the 1 minute milling process. The content of the theaflavins was measured after standing for 24 hours and 120 hours. The content of TF3G, TF3G, and TFDG was reduced after 120 hours relative to that after 24 hours, but not completely converted to TF as in Example 2. This is believed to be due to an increased content of TF3G, TF3G, and TFDG in the 3 minute shaking step, the hydrolysis reactions did not proceed to completion within 120 hours. An even longer standing time will be required. It is also believed that TF3G, TF3G, and TFDG are increased in the 3 minutes shaking step, but is not completely hydrolyzed within 120 hours, because the hydrolysis of EGCG and ECG easily proceeds while the hydrolysis of TF3G, TF3G, and TFDG hardly proceeds (comparison among Examples 2, 4, and 5). The mixer ...
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
Anti-bacterial effect:. Choleve is rich in theaflavins. A group of researchers from US department of Agriculture conducted a research to evaluate the antimicrobial activities of theaflavins from tea. The bacteria strain they used is Bacillus cereus (strain RM3190). The results demonstrate that theaflavins showed antimicrobial activities at nanomolar level; they were more active than were medicinal antibiotics, such as tetracycline or vancomycin, at comparable concentrations.. Reference:. Friedman M, Henika PR, Levin CE, Mandrell RE, Kozukue N: Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus. Journal of Food Protection 2006; 69(2): 354-361. Anti-viral effect:. Theaflavin derivatives and catechin derivatives are the major polyphenols in black tea and green tea, respectively. Several tea polyphenols, especially those with galloyl moiety, can inhibit HIV-1 replication with multiple mechanisms of action. Researchers showed that the theaflavin ...
Stenotrophomonas maltophilia is an important opportunistic nosocomial pathogen that shows intrinsic resistance to many antibiotics. This often limits treatment options and can cause lengthy hospital stays. Combination treatments are often used to combat resistance and using natural compounds such as polyphenols could give increased treatment options and even the reuse of antibiotics to which high levels of resistance have been observed. A checkerboard assay was used to determine if any synergy exists between ampicillin and the polyphenol theaflavin against 9 clinical isolates and one control isolate (NCTC 13014) of S. maltophilia. It was discovered that significant synergy (P  0.05) does exist between theaflavin and ampicillin, reducing the mean MIC of ampicillin from 12.5-22.9 µg/mL, in liquid culture, to 3.125-6.25 µg/mL. The FIC index was calculated to be 0.22-0.35 confirming synergy. From these results, significant potential for medical applications can be seen and further investigation ...
Abstract. The antioxidant and membrane effects of dimer (Dim) and trimer (Trim) procyanidins isolated from cocoa (Theobroma cacao) (B- and C-bonded) and peanut (Arachis hypogea L.) skin (A-bonded) were evaluated in phosphatidyl choline liposomes. When liposomes were oxidized with a steady source of oxidants, the above dimers and trimers inhibited to a similar extent lipid oxidation in a concentration (0.33-5 microM)-dependent manner. With respect to membrane effects, Dim A1, Dim B, Trim A, and Trim C increased (Dim A1 = Dim B and Trim A = Trim C), while Dim A2 decreased, membrane surface potential. All of the procyanidins tested decreased membrane fluidity as determined by fluorescent probes at the water-lipid interface, an effect that extended into the hydrophobic region of the bilayer. Both dimers and trimers protected the lipid bilayer from disruption by Triton X-100. The magnitude of the protection was Dim A1 , Dim A2 , Dim B and Trim C , Trim A. Thus, dimers and trimers can interact with ...
As for the beneficial changes, I think these can be largely lied to the Amla and Pycnogenol supplements. Both are strong antioxidants and both have documented impact on C Reactive Protein. After examining studies on the likely effects of amla (Indian gooseberry) and Pycnogenol (French maritime pine bark), it seems like they plus nattokinase (a proteolyic enzyme) may make a powerful one-two-three punch against cardiovascular disease by lowering inflammation, clearing out blood vessels, reducing oxidative damage to lipids and cells, and lowering the amount of clot-inducing fibrinogen that in most people is far higher than they need. I mention nattokinase for two reasons. One is that the outspoken Dr. David Williams promotes the use of amla with nattokinase to reduce abnormal clotting risk in typical aging people so if you read up on amla youre likely to run across this discussion. A second is that these test results Im discussing were achieved after about 3.5 years of supplementation with ...
The objectives of this study are to evaluate the effectiveness of Pycnogenol (French maritime pine bark extract) for arm lymphedema in women following t
Spherical stem, clayey, fork-shaped branching or form a fan without secondary growth and green. The leaves are single, dealing, composite march, along the stem shape of the needle with 1-2 mm length and green. This plants have sporangium that reduced, found in the axillaries, greenish white while the fiber appear from the stem like sticky roots and brown. Grass fan has habitus herb, creep, little upright. Round stem, clayey, branching like a fork, without secondary growth and brownish white. Single leave, arranged in line around the stem, dealing, 1-2 mm length, smooth, and green. Spore from of the sporangium reduced in axillary and white. Root fibers, appear from the leafy stems and blackish brown (Hutapea, 1994).. 4. Spread of ...
Mediators of Inflammation is a peer-reviewed, Open Access journal that publishes original research and review articles on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.
New insights into the distinct roles of flavanols and procyanidins in the human body have been provided by collaborative research by Mars, Incorporated and the University of California, Davis.
It has been proven that A-type procyanidins, containing an additional ether bond, compared to B-type procyanidins are also bioavailable in vitro and in vivo. However, their bioavailability and absorption in the gastrointestinal tract remain uncertain. In this study, a model of the human adenocarcinoma stomach cell line (MKN-28) was established to explore the cellular transport of flavanolic monome ...
HOBOKEN, NJ -- (MARKET WIRE) -- May 16, 2007 -- A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol®, natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart. The study...
Researchers at the National Research Institute on Food and Nutrition have reported that Pycnogenol, an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems.
A new study has found that an antioxidant plant extract derived from the bark of the French maritime pine tree could substantially improve those nagging symptoms most of us know so well
Supplementary MaterialsSupplemental Material kcbt-20-01-1504718-s001. inhibitor treatments) into a total cell death response when PF384 and PD901 are combined. This response was also impartial of KRAS mutation, occurring in both BxPC3 (wildtype) and MIA-PaCa-2 (mutant PDAC cells. gene is usually mutated in ~?90% of PDAC and is thought to be an early and initiating event, which in combination with cooperative genetic alterations (and and mutational status. In part the ambiguity surrounding this may relate to particular cancer types. For instance, mTOR inhibition continues to be found to diminish appearance of Mcl-1 in colorectal cancers cells, but only once mutations had been present.30 Compared, the dual PI3K/mTOR inhibitor BEZ235 acquired no influence on Mcl-1 expression in PDAC cell lines regardless of status,31 but reduced expression in ovarian cancer cell Procyanidin B1 lines.32 Additionally, while MEK inhibition is more reported to improve or stabilise appearance of Bim commonly, its been ...
Guys, ada yang suka minum Black Tea? Hmm...Aku sendiri sebenarnya bukan pecinta fanatik black tea, tapi aku gak asing dengan minuman yang satu ini. Selalu ada di kantin dan penyegar yang paling murah harganya hihihii...Gak lama ini ada tugas matakuliah yang topiknya seputar Black Tea. Setelah dikerjain dan nyari banyak referensi ternyata black tea ini…
As for comments, please find a relevant post and write your comment there. Theres no point asking for help with your lotion bar on a post about conditioners as no one will see it but you. Please find something that relates by doing a search or looking at sections like hair care, newbie links, or extracts, for example, post your comments there. Itll make it easier for other people to help you if I cant find time, too. If you post something that is very clearly not related to the post in which youre asking for help, it will go unanswered by me. ...
Explore Our Black Teas, Including Loose Leaf, Organic, Herbal & More. Shop Our Tea Store Online Today!, Popularity: Award Winning, Origin: Art of Tea Blend, Mood: Rejuvenating, Flavor: Fruity
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Drinking black tea provides many health benefits. Use this guide to learn the health benefits of drinking black tea, including heart health and more.
|P| While over indulging in anything is not good, drinking black tea in moderate amounts has a vast variety of health benefits. Black tea promotes oral healthy while h...
Consumed in moderation, black tea is beneficial. Besides temporarily boosting alertness, black tea contains helpful substances that may prevent a number of diseases and conditions, including reducing...
Black tea is one of the varieties most consumed in the world. It is an oxidized tea, with an agreeable flavor and a slight orange color. A natural source of satiating and digestive .
An age-delay treatment that smoothes the appearance of fine lines and wrinkles while providing a firmer, luminous look. Fresh, Inc.
Biflavonoids Amentoflavone many (C6-C3)n,. (C6)n,. (C6-C3-C6)n n , 12 Lignins,. Catechol melanins,. Flavolans (Condensed ...
Leaflets also contain biflavonoids. Estragole is the primary volatile compound emitted from the male and female cones of C. ... Moderately Active Antibacterial Biflavonoids. Abeer Moawad, Mona Hetta, Jordan K. Zjawiony, Melissa R. Jacob, Mohamed Hifnawy, ...
The two biflavonoids, 3′-O-methyl loniflavone and loniflavone, along with luteolin and chrysin, can be isolated from the leaves ... Kumar, Neeraj; Singh, Bikram; Bhandari, Pamita; Gupta, Ajai P.; Uniyal, Sanjay K.; Kaul, Vijay K. (2005). "Biflavonoids from ...
Biflavonoids from Ochna lanceolata v t e. ...
Biflavonoids are a type of flavonoids with the general formula scheme (C6-C3-C6)2. Amentoflavone (bis-apigenin coupled at 8 and ... "Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata". Phytochemistry. 66 (16): 1922-1926. doi:10.1016/j. ... revoluta contain biflavonoids such as (2S, 2′′S)-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-O-methylamentoflavone ( ... Moderately active antibacterial biflavonoids". Planta Med. 76 (8): 796-802. doi:10.1055/s-0029-1240743. PMC 3711132. PMID ...
Williams, Christine A.; Harborne, Jeffrey B.; Tomas-Barberan A., Francisco (1987). "Biflavonoids in the primitive monocots ...
To date, the field of biochemistry of biflavonoids is still wide open. Little is known about Ochnaflavone of its natural ...
"Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis". International Journal of ...
Leaflets of C. circinalis contain biflavonoids such as (2S, 2′′S)-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-O-methylamentoflavone ( ... Phytochemical Investigation of Cycas circinalis and Cycas revoluta Leaflets: Moderately Active Antibacterial Biflavonoids. ...
... a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids". Planta Medica. 55 (2): 166-8. doi ...
Both biflavonoids were obtained in small quantities, and their structures show some new and unusual biflavonoid diversity. ... The leaves of Lophira alata afforded two new biflavonoids, lophirone L (1) and lophirone M (2), and the known luteolin and ...
... , an isolate of Garcinia dulcis, belongs to the family of biflavonoids and is an inhibitor of HMG-CoA reductase. ...
1978). Direct synthesis, structure and absolute configuration of biflavonoids from black wattle bark (mimosa) extract. J. Chem ...
... biflavonoids MeSH D03.438.150.266.450.206 - catechin MeSH D03.438.150.266.450.221 - chalcones MeSH D03.438.150.266.450.221.500 ... biflavonoids MeSH D03.830.219.266.450.206 - catechin MeSH D03.830.219.266.450.221 - chalcones MeSH D03.830.219.266.450.221.500 ...
The biflavonoids 2",3"-dihydrohinokiflavone, 2,3,2",3"-tetrahydrohinokiflavone, 2,3-dihydroamentoflavone, 2,3,2",3"- ...
The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu2+, was studied ... The flavanone-(3→8)-flavone biflavonoids displayed antioxidant activity, particularly morelloflavone, which was significantly ... Six biflavonoids were isolated from G. madruno, one of which, 7-O-(6-acetyl)-glucoside of morelloflavone, is a new ... Six biflavonoids were isolated from G. madruno, one of which, 7-O-(6-acetyl)-glucoside of morelloflavone, is a new ...
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of ... Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of ... Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis. Li-Yin Chen 1,* , Ih-Sheng ... Chen L-Y, Chen I-S, Peng C-F. Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis ...
Natural biflavonoids as potential therapeutic agents against microbial diseases José C J M D S Menezes 1 , Vinícius R Campos 2 ... Natural biflavonoids as potential therapeutic agents against microbial diseases José C J M D S Menezes et al. Sci Total Environ ... Antiviral activities of biflavonoids. Lin YM, Flavin MT, Schure R, Chen FC, Sidwell R, Barnard DL, Huffman JH, Kern ER. Lin YM ... Biochemical pharmacology of biflavonoids: implications for anti-inflammatory action. Kim HP, Park H, Son KH, Chang HW, Kang SS. ...
Mulitple sources of biflavonoids.. Posted by iHerb Customer on Mar 10, 2010 , Verified Purchase ...
Biflavonoids Amentoflavone many (C6-C3)n,. (C6)n,. (C6-C3-C6)n n , 12 Lignins,. Catechol melanins,. Flavolans (Condensed ...
Biflavonoids +; cuticle wax tubules with nonacosan-10-ol; ferulic acid ester-linked to primary unlignified cell walls, silica ...
Biflavonoids* * Cacao / chemistry * Catechin* * Chromatography, High Pressure Liquid / methods * Fabaceae / chemistry * ...
Biflavonoids +; ferulic acid ester-linked to primary unlignified cell walls, silica usu. low; root apical meristem organization ...
Biflavonoids +; ferulic acid ester-linked to primary unlignified cell walls, silica usu. low; root apical meristem organization ... Plant (deciduous), ectomycorrhizal; specialized resin diterpenes [e.g. with abietane/pimarane skeletons], biflavonoids 0, (2-6- ...
Biflavonoids. Lignans and Neolignans. Tannins. 8--Alkaloids. Pyrrolidine and Piperidine Alkaloids. Tropane Alkaloids. ...
S. sellowii may be a potential source of biflavonoids that could provide promising compounds for the treatment of cutaneous ... Animals , Female , Mice , Antiprotozoal Agents/therapeutic use , Biflavonoids/therapeutic use , Leishmania/drug effects , ... In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) ... In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella ...
1 The Anthocyanins.- 2 Flavans and Proanthocyanidins.- 3 C-Glycosylflavonoids.- 4 Biflavonoids.- 5 Isoflavonoids.- 6 ...
Biflavonoids* * Catechin / analysis * Chromatography, High Pressure Liquid * Ellagic Acid / analysis * Fruit / chemistry* ...
Biflavonoids*. Cacao*. Catechin / pharmacology*. Cell Division / drug effects. Endothelial Cells / drug effects*. Gene ... 0/Antioxidants; 0/Biflavonoids; 0/Plant Extracts; 0/Proanthocyanidins; 154-23-4/Catechin; 4852-22-6/procyanidin; EC 2.7.10.1/ ...
Biflavonoids. Lignans and Neolignans. Tannins. 8--Alkaloids. Pyrrolidine and Piperidine Alkaloids. Tropane Alkaloids. ...
Hemingway, R.W. Biflavonoids and proanthocyanidins. In:Rowe, J.W. (ed.) Natural Products Extraneous to the Lignocellulosic Cell ...
Williams, Christine A.; Harborne, Jeffrey B.; Tomas-Barberan A., Francisco (1987). "Biflavonoids in the primitive monocots ...
Antiviral activities of biflavonoids LIN Y. M. Planta Med. 65, 120-125, 1998 ...
Leaflets also contain biflavonoids. Estragole is the primary volatile compound emitted from the male and female cones of C. ... Moderately Active Antibacterial Biflavonoids. Abeer Moawad, Mona Hetta, Jordan K. Zjawiony, Melissa R. Jacob, Mohamed Hifnawy, ...
The two biflavonoids, 3′-O-methyl loniflavone and loniflavone, along with luteolin and chrysin, can be isolated from the leaves ... Kumar, Neeraj; Singh, Bikram; Bhandari, Pamita; Gupta, Ajai P.; Uniyal, Sanjay K.; Kaul, Vijay K. (2005). "Biflavonoids from ...
DNA topoisomerase inhibitors: biflavonoids from Ouratea species. Grynberg, N.F.; Carvalho, M.G.; Velandia, J.R.; Oliveira, M.C. ...
Presentation] Biflavonoids from the roots of Diplomorpha canescens. *. Author(s). Hari Prasad Devkota, Khem Raj Joshi, 渡邊高志, 矢原 ... Journal Article] Biflavonoids, Lignans and Related Compounds from the Roots of Diplomorpha canescens2015. *. Author(s). Hari ... Journal Article] Isolation, Structure Determination, and Anti-HIV Evaluation of Tigliane-Type Diterpenes and Biflavonoids from ...
Biflavonoids and other Phenolics from Caesalpinia pyramidalis (Fabaceae). Marcus V. Bahia; Jamile B. dos Santos; Juceni P. ... Biflavonoids and other Phenolics from Caesalpinia pyramidalis (Fabaceae). J. Braz. Chem. Soc. 2005;16(6b):1402-1405. ...
Citrus Biflavonoids. 200 mcg. Selenium. 2 mcg. Proprietary Antioxidant Blend: Brewers Yeast Cinnamon, Turmeric Root, Powder, ...
Al-Shagdari, A., Alarcón, A. B., Cuesta-Rubio, O., Piccinelli, A. L., and Rastrelli, L. (2013). Biflavonoids, main constituents ...
... flavonoid glycosides and biflavonoids in Olea europaea L. leaves. Chromatographia, 33(7-8), 369-373.CrossRefGoogle Scholar ...
... biflavonoids in skin and fiber assist in restoring tissue integrity in respiratory system.. Other beneficial foods: carrot ...
Structural elucidation and bioactivity of biflavonoids from the stems of Wikstroemia taiwanensis. International Journal of ...
Biflavonoids and polyflavonoids [PK1204]. Isoflavonoids [PK1205]. Rotenoid flavonoids [PK1206]. Pterocarpans [PK1207]. ...
Biflavonoids and polyflavonoids [PK1204]. PubChem CID. 5281599. KEGG ID. C10017. CHEBI ID. 2512. ...
  • Members of this family are characterised by the presence of flavonoids, biflavonoids and terpenoids as main secondary metabolites. (scielo.org.za)
  • From Ormocarpum kirkii, a series of known flavonoids and biflavonoids was obtained, as well as three new compounds, i.e., 7,7′′-di-O-β-D-glucosyl-(−)-chamaejasmin, 7-O-β-D-glucosyl-(I-3,II-3)-biliquiritigenin, and isovitexin-(I-3,II-3)-naringenin. (sigmaaldrich.com)
  • It contains flavonoids (flavonol glycoside and non-glycosidid biflavonoids), unique diterpene lactones (gingolides A, B, C, J and M) as well as a sesquiterpenoid (bilobalide). (ageless.co.za)
  • This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from this plant (SSHE), as well as of the biflavonoids amentoflavone and robustaflavone, isolated from this species. (bvsalud.org)
  • Amentoflavone is one of the plant-derived biflavonoids currently being explored for potent pharmacological activities. (alliedacademies.org)
  • Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts," Bioorganic and Medicinal Chemistry , vol. 16, no. 2, pp. 732-738, 2008. (hindawi.com)
  • 2000. Cytotoxic biflavonoids from Selaginella deliccatula. (koreascience.or.kr)
  • Benzophenones are the major secondary metabolites in G. gummi-gutta, followed by xanthones and biflavonoids. (healthbenefitstimes.com)
  • Previous activity-guided phytochemical studies on Garcinia buchananii stem bark, which is traditionally used in Africa to treat various gastrointestinal and metabolic illnesses, revealed xanthones, polyisoprenylated benzophenones, flavanone-C-glycosides, biflavonoids, and/or biflavanones as bioactive key molecules. (tum.de)
  • This compound belongs to the class of organic compounds known as biflavonoids and polyflavonoids. (hmdb.ca)
  • Osorio E, Londoño J, Bastida J. Low-Density Lipoprotein (LDL)-Antioxidant Biflavonoids from Garcinia madruno . (mdpi.com)
  • Six biflavonoids were isolated from G. madruno , one of which, 7''- O -(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. (mdpi.com)
  • The flavanone-(3→8'')-flavone biflavonoids displayed antioxidant activity, particularly morelloflavone, which was significantly more potent than quercetin, with a CE 50 of 12.36 μg/mL. (mdpi.com)
  • commonly, the ongoing reductions of other Complete 2001)Biflavonoids warnings are suggested founded and indexed adding epub Путешествие в Малороссию академика Гильденштедта и кн. (opticasoftware.com)
  • An 2001)Biflavonoids interface for agreeing sustainable unangenehm and the protection of sodium plaintiffs( P. Water deficiency and the gesperrt. (opticasoftware.com)
  • Unequivocal structure elucidation of biflavonoids and biflavanones by means of NMR spectroscopy is often complicated by the hindered rotation of the monomers around the C-C axis (atropisomerism), resulting in a high spectral complexity. (tum.de)
  • Recent reports have shown that synthetic biflavonoids are now produced for specific therapeutic uses [ 6 ]. (alliedacademies.org)
  • Approximately 109 phytochemical constituents have been searched out as isolates from various parts of this plant comprising mostly diterpenoids and biflavonoids. (eurekaselect.com)
  • Biflavonoids are generally known for a wide number of pharmacological potentials in different countries and they are found in limited number of plants with interesting medicinal and pharmacological properties. (alliedacademies.org)
  • Stafford, H.A. Enzymic regulation of procyanidin biosynthesis: lack of flav-3-en-3-ol intermediate. (springer.com)
  • Three new biflavonoids, wikstaiwanones A-C ( 1 - 3 ), along with four known compounds ( 4 - 7 ) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). (mdpi.com)
  • S. sellowii may be a potential source of biflavonoids that could provide promising compounds for the treatment of cutaneous leishmaniasis . (bvsalud.org)
  • Biflavonoids are unique biologically active naturally-occurring compounds for which the attentions of researchers have been drawn over the years. (alliedacademies.org)
  • The two biflavonoids, 3′-O-methyl loniflavone and loniflavone, along with luteolin and chrysin, can be isolated from the leaves. (wikipedia.org)
  • The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu 2+ , was studied by means of a TBARS assay. (mdpi.com)
  • Biflavonoids found in oranges, grapefruit, lemons and limes. (msu.edu)
  • Biflavonoids are found in citrus fruits. (nyhq.org)
  • Flavone-flavone, flavanone-flavone and flavanone-flavanone are the common subunits found in plant-derived biflavonoids [ 1 , 4 ]. (alliedacademies.org)
  • Anti-virulence activities of biflavonoids from Mesua ferrea L. flower. (nih.gov)
  • However, the connecting linkages are present at diverse positions yielding more than a hundred biflavonoids which have been isolated and structurally characterized till date [ 1 , 5 ]. (alliedacademies.org)
  • Structure, synthesis and biological activities of biflavonoids isolated from Ochna serrulata (Hochst. (ukzn.ac.za)
  • Biological evaluation for these [38]-biflavonoids against four human tumor cell lines, including oral epidermoid carcinoma (KB), breast carcinoma (MCF-7), colon adenocarcinoma (DLD) and laryngeal carcinoma (HEp-2), as well as the analysis of apoptosis. (icrs-world-congress.org)