Bicyclo compounds. Medical search

A class of saturated compounds consisting of two rings only, having two or more atoms in common, containing at least one hetero atom, and that take the name of an open chain hydrocarbon containing the same total number of atoms. (From Riguady et al., Nomenclature of Organic Chemistry, 1979, p31)

Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.

Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)

The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products.

The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Drugs that selectively bind to and activate ADENOSINE A3 RECEPTORS.

Compounds that selectively bind to and block the activation of ADENOSINE A3 RECEPTORS.

Attachment of isoprenoids (TERPENES) to other compounds, especially PROTEINS and FLAVONOIDS.

An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.

Rhodium. A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh. (Dorland, 28th ed)

A group of compounds with an 8-carbon ring. They may be saturated or unsaturated.

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.

A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAIN and endocrine tissues. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.

Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)

Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.

Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).

Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The characteristic three-dimensional shape of a molecule.

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.

Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.

Inorganic or organic compounds that contain sulfur as an integral part of the molecule.

Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)

Exclusive legal rights or privileges applied to inventions, plants, etc.

Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)

Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.

The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

Four fused benzyl rings with three linear and one angular, that can be viewed as a benzyl-phenanthrenes. Compare with NAPHTHACENES which are four linear rings.

Processes by which phototrophic organisms use sunlight as their primary energy source. Contrasts with chemotrophic processes which do not depend on light and function in deriving energy from exogenous chemical sources. Photoautotrophy (or photolithotrophy) is the ability to use sunlight as energy to fix inorganic nutrients to be used for other organic requirements. Photoautotrophs include all GREEN PLANTS; GREEN ALGAE; CYANOBACTERIA; and green and PURPLE SULFUR BACTERIA. Photoheterotrophs or photoorganotrophs require a supply of organic nutrients for their organic requirements but use sunlight as their primary energy source; examples include certain PURPLE NONSULFUR BACTERIA. Depending on environmental conditions some organisms can switch between different nutritional modes (AUTOTROPHY; HETEROTROPHY; chemotrophy; or phototrophy) to utilize different sources to meet their nutrients and energy requirements.

A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

An independent Federal agency established in 1958. It conducts research for the solution of problems of flight within and outside the Earth's atmosphere and develops, constructs, tests, and operates aeronautical and space vehicles. (From U.S. Government Manual, 1993)

Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.

A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.

Activities performed in the preparation of bibliographic records for CATALOGS. It is carried out according to a set of rules and contains information enabling the user to know what is available and where items can be found.

Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).

A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)

A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.

A technique of operations research for solving certain kinds of problems involving many variables where a best value or set of best values is to be found. It is most likely to be feasible when the quantity to be optimized, sometimes called the objective function, can be stated as a mathematical expression in terms of the various activities within the system, and when this expression is simply proportional to the measure of the activities, i.e., is linear, and when all the restrictions are also linear. It is different from computer programming, although problems using linear programming techniques may be programmed on a computer.

The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.

A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.

Substances used to obtain a lighter skin complexion or to treat HYPERPIGMENTATION disorders.

Coloration of the skin.

Drugs used to treat or prevent skin disorders or for the routine care of skin.

Insoluble polymers of TYROSINE derivatives found in and causing darkness in skin (SKIN PIGMENTATION), hair, and feathers providing protection against SUNBURN induced by SUNLIGHT. CAROTENES contribute yellow and red coloration.

A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections.

Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.

Drug-protein binding and blood-brain barrier permeability. (1/549)

The permeability surface area (PS) product, an index of permeability of the blood-brain barrier (BBB), was measured by using the in situ perfusion method. In the cerebral circulation, the fraction of drug that permeates into the brain through the BBB is not only the unbound fraction but also the fraction dissociated from the protein in the perfusate. The sum of these two fractions, the apparent exchangeable fraction, was estimated by fitting the parameters of the BBB permeability under the condition of varying BSA concentrations in the perfusate. The unbound fraction of drugs in a buffer containing 0.5 mM BSA was measured by using the ultrafiltration method in vitro, and the apparent exchangeable fraction was measured in vivo by using the intracarotid artery injection method. The apparent exchange fraction was 100% for S-8510, 96.5% for diazepam, 90.9% for caffeine, 38.3% for S-312-d, 33.1% for propranolol, and 6.68% for (+)-S-145 Na, and each of these was higher than the corresponding unbound fraction in vitro in all drugs. The apparent exchangeable fractions, for example, were 8 times higher for diazepam and 38 times for S-312-d than the unbound fractions in vitro. The apparent exchangeable fraction of drugs was also estimated from the parameters obtained with the perfusion method. Because drugs can be infused for an arbitrary length of time in the perfusion method, substances with low permeability can be measured. The apparent exchangeable fractions obtained with this method were almost the same as those obtained with the intracarotid artery injection method. (+info)

Influence of a new antiulcer agent, ammonium 7-oxobicyclo (2, 2, 1) hept-5-ene-3-carbamoyl-2-carboxylate (KF-392) on gastric lesions and gastric mucosal barrier in rats. (2/549)

Antiulcer effects of KF-392 were studied in several experimental gastric ulcer models in rats. It was found that KF-392 given orally at 1.0 to 5.0 mg/kg had a marked suppression on the developments of Shay ulcer as well as the aspirin-, stress-, and reserpine-induced gastric lesions. The influence of KF-392 on gastric mucosal barrier was also studied. A back diffusion of H+ into the gastric mucosa and a fall of transmucosal potential difference were induced with KF-392 given orally at the above mentioned doses. KF-392 given s.c. at 5.0 mg/kg showed no inhibition of Shay ulcer and no induction of back diffusion of H+ into the gastric mucosa. (+info)

Isolation and structural determination of a novel bicyclic taxane diterpene from needles of the Chinese yew, Taxus mairei. (3/549)

A novel bicyclic taxane diterpene with a rare 12-membered ring was isolated from needles of the Chinese yew, Taxus mairei, and its structure was established as (3E, 8E)-2 alpha, 7 beta, 9, 10 beta, 13 alpha, 20-hexaacetoxy-5(2'-acetoxy-cinnamoyloxy)-3,8-secotaxa -3,8,11-triene (1) with the help of 1D and 2D NMR data. The relative stereochemistry was deduced from a NOESY experiment. (+info)

Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. (4/549)

We examined the effects of modulating group II metabotropic glutamate receptors (mGluRs) on traumatic neuronal injury using both in vitro and in vivo models. Treatment with various selective group II mGluR agonists significantly decreased lactate dehydrogenase release, a marker of cell death, after traumatic injury to rat neuronal-glial cultures; injury-induced increases in cyclic AMP and glutamate levels were also significantly reduced by a group II agonist. The neuroprotective effects of group II agonists were markedly attenuated by coadministration of a group II antagonist or a membrane-permeable cyclic AMP analog and were additive to those provided by an N-methyl-D-aspartate receptor antagonist or a selective group I mGluR antagonist. Administration of a group II mGluR agonist 30 min after lateral fluid percussion-induced brain injury in rats significantly improved subsequent behavioral recovery as compared with vehicle-treated controls. Together these studies indicate that group II mGluR agonists protect against traumatic neuronal injury by attenuating glutamate release and cAMP levels and suggest a potential role for these agents in the treatment of clinical neurotrauma. (+info)

Endothelium-derived contracting factor in carotid artery of hypertensive Dahl rats. (5/549)

The present study is designed to investigate whether acetylcholine (ACh) elicits an endothelium-derived contracting factor (EDCF) and whether it contributes to decreased relaxant response induced by ACh in Dahl rats. Dahl salt-sensitive (DS) and -resistant (DR) rats were fed a 0.4% NaCl or an 8% NaCl diet for 4 weeks. High sodium intake significantly increased blood pressure in DS rats but not in DR rats. The carotid rings were suspended for isometric tension recording. ACh caused an endothelium-dependent contraction in carotid rings from hypertensive DS rats but not from normotensive Dahl rats. Atropine, indomethacin, SQ29548, or ONO-3708 (prostaglandin H(2) [PGH(2)]/thromboxane A(2) [TXA(2)] receptor antagonist) abolished ACh-induced contraction, and OKY-046 (inhibitor of TXA(2) synthetase) partially attenuated the contraction. High sodium intake significantly enhanced contraction evoked by U46619, a PGH(2)/TXA(2) receptor agonist, in both DS and DR rats. In contrast, ACh-induced relaxation was significantly depressed in the rings from hypertensive DS rats, and ONO-3708 partially improved the depressed relaxation. Administration of ONO-8809 (an orally active PGH(2)/TXA(2) receptor antagonist; 30 micrograms per body per day) for 4 weeks neither reduced blood pressure nor improved the depressed ACh-induced relaxation in hypertensive DS rats. These results suggest that ACh causes release of EDCF in carotid rings of hypertensive DS rats, which is likely to be PGH(2) and TXA(2). The EDCF contributed in part to the depressed ACh-induced relaxation. (+info)

Fatty acid translocase/CD36 mediates the uptake of palmitate by type II pneumocytes. (6/549)

Type II pneumocytes, which synthesize, store, and secrete pulmonary surfactant, require exogenous fatty acids, in particular palmitic acid, for maximum surfactant synthesis. The uptake of palmitate by type II pneumocytes is thought to be protein mediated, but the protein involved has not been characterized. Here we show by RT-PCR and Northern blot analysis that rat type II pneumocytes express the mRNA for fatty acid translocase (FAT/CD36), a membrane-associated protein that is known to facilitate the uptake of fatty acids into adipocytes. The deduced amino acid sequence from rat type II pneumocytes reveals 98% identity to the FAT/CD36 sequence obtained from rat adipocytes. The uptake of palmitate by type II pneumocytes follows Michaelis-Menten kinetics (Michaelis-Menten constant = 11.9 +/- 1.8 nM; maximum velocity = 62.7 +/- 5.8 pmol. min(-1). 5 x 10(5) pneumocytes(-1)) and decreases reversibly under conditions of ATP depletion to 35% of control uptake. Incubation of cells at 0 degrees C inhibited the uptake of palmitate almost completely, whereas depletion of potassium was without effect. Preincubation of the cells with bromobimane or phloretin decreases the uptake of palmitate significantly as does preincubation with sulfo-N-succinimidyl oleate, the specific inhibitor of FAT/CD36 (C. M. Harmon, P. Luce, A. H. Beth, and N. A. Abumrad. J. Membr. Biol. 121: 261-268, 1991). From these data, we conclude that FAT/CD36 is expressed in type II pneumocytes and mediates the uptake of palmitate in a saturable and energy-dependent manner. The data suggest that the uptake process is independent of the formation of coated pits and endocytotic vesicles. (+info)

Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1. (7/549)

Extracts of Hypericum perforatum (St. John's Wort) are widely used for the treatment of depressive disorders and are unspecific inhibitors of the neuronal uptake of several neurotransmitters. Previous studies have shown that hyperforin represents the reuptake inhibiting constituent. To characterize the mechanism of serotonin reuptake inhibition, kinetic analyses in synaptosomes of mouse brain were performed. Michaelis-Menten kinetics revealed that hyperforin (2 microM) induces a decrease in V(max) by more than 50% while only slightly decreasing K(m), indicating mainly noncompetitive inhibition. By contrast, citalopram (1 nM) leads to an elevation of K(m) without changing V(max). Monensin, a Na(+)/H(+) exchanger, showed similar properties as hyperforin (decrease of V(max) without changing K(m)). Compared with classical antidepressants, such as selective serotonin reuptake inhibitors and tricyclic antidepressants, hyperforin is only a weak inhibitor of [(3)H]paroxetine binding relative to its effects on serotonin uptake. As monensin decreases serotonin uptake by increasing Na(+)/H(+) exchange, we compared the effects of hyperforin and monensin on the free intracellular sodium concentration ([Na(+)](i)) in platelets by measuring 1,3-benzenedicarboxylic acid, 4,4'-[1,4,10-trioxa-7, 13-diazacyclopentadecan-7,13-diylbis(5-methoxy-6, 2-benzofurandiyl)]bis-, tetraammonium salt (SBFI/AM) fluorescence. Both drugs elevated [Na(+)](i) over basal levels, with a maximal [Na(+)](i) of 69 +/- 16.1 mM (50 microM hyperforin) and 140 +/- 9.1 mM (10 microM monensin). Citalopram at concentrations relevant for [(3)H]serotonin uptake inhibition had no effect on [Na(+)](i). Although the mode of action of hyperforin seems to be associated with elevated [Na(+)](i) similar to those levels found with monensin, the molecular mechanism might be different, as even at high concentrations, hyperforin does not elevate free intracellular sodium concentration ([Na(+)](i)) up to the extracellular level, as monensin does. Hyperforin represents the first substance with a known preclinical antidepressant profile that inhibits serotonin uptake by elevating [Na(+)](i). (+info)

Cross-resistance with dieldrin of a novel tricyclic dinitrile GABA receptor antagonist. (8/549)

A novel tricyclic dinitrile, KN244, blocked the wild-type (dieldrin-sensitive) homo-oligomeric gamma-aminobutyric acid (GABA)-gated chloride channel of Drosophila melanogaster expressed in Xenopus oocytes. Sensitivity to the block by KN244 of the response to 30 microM GABA (IC50=41.6 nM, wild-type RDLac) was reduced abut 100 fold (IC50=4.5 microM) in the dieldrin-resistant (RDLacA302S) form of RDL. (+info)

The simplest polyquinane is the bicyclic compound bicyclo[3.3.0]octane. Other members are triquinacene and dodecahedrane. The ... A polyquinane polycyclic compound consisting of fused five-membered hydrocarbon rings. If the compound is unsaturated instead ... compound triquinacene, sometimes simply called quinacene (tricyclo[5.2.1.04,10]deca-2,5,8-triene) is the second member of a ... it was found to have no such properties-and also as part of a failed attempt to synthesize the then-elusive compound ...

https://en.wikipedia.org/wiki/Polyquinane

Fused and bridged bicyclic compounds get the prefix bicyclo, whereas spirocyclic compounds get the prefix spiro. In between the ... Therefore, fused bicyclic compounds have a "0" included in the brackets. For example, decalin is named bicyclo[4.4.0]decane. ... An example of a spirocyclic compound is the photochromic switch spiropyran. In fused bicyclic compounds, two rings share two ... When naming simple fused bicyclic compounds, the same method as for bridged bicyclic compounds is applied, except the third ...

https://en.wikipedia.org/wiki/Bicyclic_molecule

Structurally similar to paraherquamides, they are a small class compounds that contain a bicyclo[2.2.2]diazoctane ring system. ...

https://en.wikipedia.org/wiki/Brevianamide

... (also known as bicyclo[2.2.1]heptane) is an organic compound and a saturated hydrocarbon with chemical formula C7H12 ... and is a bridged bicyclic compound. The compound is a prototype of a class of strained bicyclic hydrocarbons. The compound was ... It is a crystalline compound with a melting point of 88 °C. The carbon skeleton is derived from cyclohexane ring with a ... das Bicyclo-[1.2.2]-heptan, und die stereoisomeren Norborneole". Naturwissenschaften. 22: 171. doi:10.1007/BF01496254. ...

https://en.wikipedia.org/wiki/Norbornane

With this reaction, compounds with bicyclo skeletons can be synthesized, e.g. a diester with a norbornene (bicyclo[2.2.1] ... The compound (and its metabolite, monomethyl fumarate) activates the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway ... As a α,β-unsaturated electrophilic compound, dimethyl fumarate is rapidly attacked by the detoxifying agent glutathione (GSH) ... Boyland, E; Chasseaud, LF (1967). "Enzyme-catalysed conjugations of glutathione with unsaturated compounds". The Biochemical ...

https://en.wikipedia.org/wiki/Dimethyl_fumarate

... octane Bicyclo[3.3.0]octane (polyquinane) Bicyclo[3.2.1]octane https://pubchem.ncbi.nlm.nih.gov/compound/Bicyclo_3.2.1_octane ... 7-Octadiene Octynes 1-Octyne 2-Octyne 3-Octyne 4-Octyne Bicyclooctane Bicyclo[2.2.2] ...

https://en.wikipedia.org/wiki/C8H14

Instead, the group proposed the structure of the bicyclo[5.1.0]octadienyl compound, theorizing that the cyclopropane bond ... Similarly, a substituted bicyclo[3.2.1]octa-3,6-dien-2-yl cation (the 2-(4'-Fluorophenyl) bicyclo[3.2.1]oct-3,6-dien-2-yl ... These anionic compounds are often prepared from their neutral parent compounds through lithium metal reduction. 1,2- ... Just as aromatic compounds exhibit exceptional stability, antiaromatic compounds, which deviate from Huckel's rule and contain ...

https://en.wikipedia.org/wiki/Homoaromaticity

... (decahydronaphthalene, also known as bicyclo[4.4.0]decane and sometimes decaline), a bicyclic organic compound, is an ...

https://en.wikipedia.org/wiki/Decalin

Bicyclo[1.1.1]pentane is an organic compound, the simplest member of the bicyclic bridged compounds family. It is a hydrocarbon ... Bicyclo[1.1.1]pentane is a highly strained molecule. Kenneth Wiberg and Frederick Walker used bicyclo[1.1.1]pentane to make [ ... The bicyclo[1.1.1]pentane structure has been used as an unusual bioisostere for a phenyl ring. Housane Wiberg, Kenneth B.; ... "Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally ...

https://en.wikipedia.org/wiki/Bicyclo(1.1.1)pentane

Bicyclo[6.2.0]decapentaene is a bicyclic organic compound and an isomer of naphthalene and azulene. Whether this substance is ... Bicyclo[6.2.0]decapentaene can be synthesised in a multistep process from bicyclo[4.2.0]octa-3,7-diene-2,5- dione. This is ... Bicyclo[6.2.0]decapentaene dissolves in pentane. Bicyclo[6.2.0]decapentaene reacts with oxygen in air. When heated to 100 °C it ... Unlike aromatic compounds, it has alternating bond lengths in the rings. One double bond is in the exclusive part of the four ...

https://en.wikipedia.org/wiki/Bicyclo(6.2.0)decapentaene

An iptycene is an aromatic compound composed of varying number of arene subunits bound to a bridged bicyclo-octatriene core ...

https://en.wikipedia.org/wiki/Iptycene

Doering, W. von E.; Roth, W. R. (1963). "A Rapidly Reversible Degenerate Cope Rearrangement : Bicyclo[5.1.0]octa-2,5-diene". ... Verbrugge, P. A. (1977). "Unusual organic compounds. XXIV. Compounds with the formula (CH)n. (d). Synthesis of cubane, (CH)8; ... Monk, Felonious (13 April 2006). "Chemical Cock-ups: A Story of How Not to Name a Chemical Compound". h2g2: The guide to life, ... Chemical nomenclature, replete as it is with compounds with complex names, is a repository for some names that may be ...

https://en.wikipedia.org/wiki/List_of_chemical_compounds_with_unusual_names

A compound decoction of this root is administered in cases of Hemiplegia as some Indian physicians consider it useful in ... 7-tri methyl bicyclo [2.2.1] heptane) has been found in the orchid in 2013. The plant has an alkaloid, a glucoside, tannins, β- ... A Subramoniam, A Gangaprasad, P K Sureshkumar, J Radhika and B K Arun (18 April 2013). A novel aphrodisiac compound from an ... and exhibit potent analgesic effects combined with a relatively low toxicity A novel aphrodisiac compound ( 2,7, ...

https://en.wikipedia.org/wiki/Vanda_tessellata

One demonstration of this principle is found in the two bicyclic compounds depicted below. The one on the left is a bicyclo[2.2 ... Rickert Reaction in the Structures of Bicyclo[2.2.2]octadiene and Bicyclo[2.2.2]octene Derivatives". The Journal of Organic ... Compared to the compound on the right (which, lacking an alkene group, is unable to give this reaction) the bridgehead carbon- ... For these two compounds the prediction holds up based on X-ray crystallography. One way that enzymatic catalysis proceeds is by ...

https://en.wikipedia.org/wiki/Transition_state

Reaction of organic compounds under high temperature - dilute acid (HTDA) conditions. III. The perdeuteration of bicyclo[2.2.1] ... Commercially available, this colorless compound may be prepared by the reaction of norbornene with formic acid, followed by ...

https://en.wikipedia.org/wiki/Exo-Norborneol

Bicyclo(2.2.1)heptane-2-carbonitrile. *Biotin hydrazide. *2,3-Bis(acetylmercaptomethyl)quinoxaline ... This category is for stub articles relating to organic compounds. You can help by expanding them.. To add an article to this ... Pages in category "Organic compound stubs". The following 200 pages are in this category, out of approximately 1,151 total. ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Category:Organic_compound_stubs&oldid=734103263" ...

https://en.wikipedia.org/wiki/Category:Organic_compound_stubs

... , or bicyclo[4.1.0]heptane, is a colorless liquid. It is an organic compound prepared using the Simmons-Smith reaction ...

https://en.wikipedia.org/wiki/Norcarane

... pentane Bicyclo[2.1.0]pentane (housane) Bicyclopentyl (cyclopentylcyclopentane) Bicyclic compound Bicyclobutane Spiropentane ... This set index page lists chemical compounds articles associated with the same name. If an internal link led you here, you may ...

https://en.wikipedia.org/wiki/Bicyclopentane

Both routes leverage a small [2]-ladderene building block bicyclo[2.2.0]hexene prepared by a Ramberg-Bäcklund reaction. The ... Trans-ladderanes have not been synthesized due to the ring strain in these compounds. The second stereochemical relationship ... Various synthetic methods have been used for the laboratory synthesis of ladderane compounds. The three major approaches are (1 ... Elimination of H-Br and addition of an organozinc compound installs the alkyl alcohol. A hydrazine-mediated deoxygenation ...

https://en.wikipedia.org/wiki/Ladderane

... (IUPAC name: tricyclo[4.4.0.03,8]decane) is an organic compound with the formula C10H16. It is a cycloalkane and an ... The original 1962 method was based on a bicyclo[2.2.2]octane framework. A 1967 publication concerned an intramolecular aldol ... The compound was first reported by Whitlock in 1962. Twistane has been synthesized in a variety of ways. ...

https://en.wikipedia.org/wiki/Twistane

The compound 1,3-dehydroadamantane, which can be viewed as a bridged [1.3.3]propellane, also polymerizes in a similar way. [2.2 ... Propellane Bicyclo(1.1.1)pentane which lacks a bond between the bridgehead carbons. "Houben-Weyl Methods of Organic Chemistry ... 1.1.1]Propellane is an organic compound, the simplest member of the propellane family. It is a hydrocarbon with formula C5H6 or ... 3-di-carboxylic acid of bicyclo[1.1.1]pentane 1 in a Hunsdiecker reaction to the corresponding dibromide 2 followed by a ...

https://en.wikipedia.org/wiki/1.1.1-Propellane

As an oxygen-rich compound of carbon and nitrogen, it is predicted to have explosive properties,[2] but to be too thermally ... The all-carbon analog (bicyclo[1.1.1]pentane) and other elemental variations of this ring structure have been synthesized. ... The nitratoxycarbon functional group itself has yet to be observed in any chemical compound. Computational chemistry studies ... and nitrate compounds and their potential as high energy materials". Computational and Theoretical Chemistry. 979: 33-37. doi: ...

https://en.wikipedia.org/wiki/Tetranitratoxycarbon

... is a tetracyclic compound and is grouped with the TeCAs. Its chemical name is N-methyl-9,10-ethanoanthracen-9(10H)- ... This results in it having a unique three-dimensional central ring (a bicyclo[2.2.2]octane or 1,4-endoethylenecyclohexane ring) ... Tatsumi M, Groshan K, Blakely RD, Richelson E (1997). "Pharmacological profile of antidepressants and related compounds at ... and being a tetracyclic rather than a tricyclic compound. However, it could also or alternatively be considered to be a ...

https://en.wikipedia.org/wiki/Maprotiline

The perdeuteration of bicyclo[2.2.1]heptanes PDF J. K. Stille, and Fred M. Sonnenberg (1966). "The Reaction of endo- and exo-2- ... Exo-Norborneol (+)-endo-2-Norborneol at Sigma-Aldrich endo-Norborneol MSDS Reaction of organic compounds under high temperature ...

https://en.wikipedia.org/wiki/Endo-Norborneol

Benzotrichloride Benzyl chloride Benzyl cyanide Bicyclo(2.2.1)heptane-2-carbonitrile Bis(chloromethyl) ketone Bitoscanate Boron ... trichloride Boron trifluoride Boron trifluoride compound with dimethyl ether (1:1) Bromadiolone Bromine Cadmium oxide Cadmium ...

https://en.wikipedia.org/wiki/EPA_list_of_extremely_hazardous_substances

Most such compounds act as releasers of monoamine neurotransmitters, and have stimulant effects. Some also act as agonists at ... stereochemistry and anti-tetrabenazine activity of bicyclo analogues of 2-phenylmorpholines". Journal of Heterocyclic Chemistry ... Some compounds have also become subject to illicit use as designer drugs. Substituted amphetamine Substituted benzofuran ... NIH PubChem Compound Summary for CID 3283983 Media related to Substituted phenylmorpholines at Wikimedia Commons. ...

https://en.wikipedia.org/wiki/Substituted_phenylmorpholine

The compound itself was first synthesized in 1962 as a tert-butyl derivative and then as the unsubstituted compound by Eugene ... Bicyclo[2.2.0]hexa-2,5-dienes (Dewar benzenes)". J. Am. Chem. Soc. 93 (23): 6092-6101. doi:10.1021/ja00752a021. CS1 maint: ... The compound is named after James Dewar who included this structure in a list of possible C6H6 structures in 1867. However, he ... The compound has nevertheless considerable strain energy and reverts to benzene with a chemical half-life of two days. This ...

https://en.wikipedia.org/wiki/Dewar_benzene

For example, bicyclo[5.3.1]undecane-11-one-1-carboxylic acid undergoes decarboxylation on heating to 132 °C, but the similar ... There has been an active research program to seek compounds inconsistent with the rule, and for bicyclic systems a limit of S ... Köbrich, Gert (1973). "Bredt Compounds and the Bredt Rule". Angew. Chem. Int. Ed. 12 (6): 464-473. doi:10.1002/anie.197304641. ... 7 is now established with several such compounds having been prepared. The above norbornene system has S = 5 and so they are ...

https://en.wikipedia.org/wiki/Bredt's_rule

... or bicyclo[2.1.0]pentane is a saturated cycloalkane with the formula C5H8. It is a colorless volatile liquid at room ... This compound is prepared in several steps starting with cyclopentadiene. The two rings are fused in a cis configuration-this ... P. G. Gassman, K. T. Mansfield "Bicyclo[2.1.0]pentane" Org. Synth. 1969, volume 49, pp. 1. doi:10.15227/orgsyn.049.0001 v t e. ... meso compound formally has (1R,4S) absolute stereochemistry. The small size of the two rings prevents the trans isomer from ...

https://en.wikipedia.org/wiki/Housane

Safety hazards have resulted in rapid decline of DEAD usage and replacement with DIAD and other similar compounds. Diethyl azo ... Gassman PG, Mansfield KT (1969). "BICYCLO[2.1.0]PENTANE". Organic Syntheses. 49: 1. doi:10.15227/orgsyn.049.0001. ISSN 0078- ... DEAD can be used for synthesis of heterocyclic compounds. Thus, pyrazoline derivatives convert by condensation to α,β- ... P. N. Preston (1980). Benzimidazoles and congeneric tricyclic compounds. John Wiley and Sons. pp. 475-. ISBN 978-0-471-08189-0 ...

https://en.wikipedia.org/wiki/Diethyl_azodicarboxylate

"Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices". Chem Inf. Comput. Sci. 41: 1488-1493. PMID ... Reposal, 5-Ethyl-5-(bicyclo(3.2.1)octenyl)barbituric acid Farmakoinformacioni podaci ...

https://sh.wikipedia.org/wiki/Reposal

Most carbon compounds CO2 Carbon dioxide Determining the point group is a useful way to predict polarity of a molecule. In ... Examples of household nonpolar compounds include fats, oil, and petrol/gasoline. Therefore, most nonpolar molecules are water- ...

https://en.wikipedia.org/wiki/Polarity_

Brasofensine was made "class A" in the UK under the MDA (misuse of drugs act). BF is an interesting compound in so far as the ... n-dimethylaminomethyl-bicyclo-2,2,2-octane, hydrochloride". Life Sciences. 23 (10): 1041-7. doi:10.1016/0024-3205(78)90664-1. ... This is based on the fact that the compound is bicyclic and therefore does not adhere to the equation given above. It is ... Hence, this might be viewed as a strategy for increasing the safety of the compounds and would also be preferable to use in ...

https://en.wikipedia.org/wiki/Serotonin–norepinephrine–dopamine_reuptake_inhibitor

MacKenzie, DA; Pezacki, JP (2014). "Kinetics studies of rapid strain- promoted [3+2] cycloadditions of nitrones with bicyclo[ ...

https://en.wikipedia.org/wiki/Click_chemistry

Intercalation compounds are not 3-dimensional, unlike clathrate compounds.[6] According to IUPAC, clathrates are "Inclusion ... Usually, clathrate compounds are polymeric and completely envelop the guest molecule. Inclusion compounds are often molecules, ... Two potassium graphite compounds are KC8 and KC24. Carbon fluorides (e.g., (CF)x and (C4F)) are prepared by reaction of ... J. L. Atwood "Inclusion Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2012, Wiley-VCH, Weinheim. doi: 10.1002/ ...

https://en.wikipedia.org/wiki/Exfoliation_corrosion

Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State ... Reposal, 5-Ethyl-5-(bicyclo(3.2.1)octenyl)barbituric acid. Hemijski podaci. ...

https://sr.wikipedia.org/wiki/Reposal

... is an acid-labile compound. Acid-labile compounds are more easily broken down in acidic environments, so the ... N,N-dimethyl-2-([(1R,4R,6S)-1,7,7-trimethyl-6-phenyl-6-bicyclo[2.2.1]heptanyl]oxy)ethanamine ... "Inhibition of high-affinity synaptosomal uptake of gamma-aminobutyric acid by a bicyclo-heptane derivative". Arzneimittel- ...

https://en.m.wikipedia.org/wiki/Deramciclane

... s are seen in many boron compounds, such as diborane (B2H6). The monomer BH3 is unstable since ... This type of bond also occurs in carbon compounds, where it is sometimes referred to as hyperconjugation; another name for ...

https://en.wikipedia.org/wiki/Three-center_two-electron_bond

First, α-diazocarbonyl compounds are in an equilibrium of s-cis and s-trans-conformers, the distribution of which may influence ... CS1 maint: Multiple names: authors list (link) Horner, L. Spietschka, E. (1955). "Über Lichtreaktionen IV1): Bicyclo-[1.1.2]- ... α-diazocarbonyl compounds are generally locally planar, with large rotational barriers (55-65 kJ/mol) due to C-C olefin ... Generally, under photolysis, compounds in the s-cis conformation react in a concerted manner due to the antiperiplanar ...

https://en.wikipedia.org/wiki/Wolff_rearrangement

Ionic compounds conduct electricity when molten or in solution, typically as a solid. Ionic compounds generally have a high ... Many sulfides, e.g., do form non-stoichiometric compounds. Many ionic compounds are referred to as salts as they can also be ... Main article: Ionic compound. Ionic compounds in the solid state form lattice structures. The two principal factors in ... obey the rules of stoichiometry despite not being molecular compounds. For compounds that are transitional to the alloys and ...

https://en.wikipedia.org/wiki/Ionic_bond

These compounds can be liquid until a certain temperature, then solid even as the temperature increases, and finally liquid ... Lipinski CA (December 2004). "Lead- and drug-like compounds: the rule-of-five revolution". Drug Discovery Today: Technologies. ... Increase in the melting point, boiling point, solubility, and viscosity of many compounds can be explained by the concept of ... The hydrogen bond is responsible for many of the anomalous physical and chemical properties of compounds of N, O, and F. In ...

https://en.wikipedia.org/wiki/Hydrogen_bond

This result suggested that there is a high selectivity for the 3° hydrogen, but the intermediate tertiary chloro compound 17 is ... Esposito, G.; Furstoss, R.; Waegell, B. (1971). "Synthese de la methyl-6, aza-6, bicyclo (3,2,1) octanone-4". Tetrahedron Lett ... Synthesis of 1,4-epimine compounds". J. Org. Chem. 48 (23): 4430-4432. doi:10.1021/jo00171a066. De Armas, P.; Carrau, R.; ... Part 4. Intramolecular functionalization of N-nitroamine radicals: synthesis of 1,4-nitroimine compounds". J. Chem. Soc., ...

https://en.wikipedia.org/wiki/Hofmann–Löffler_reaction

Half-cell potential of aromatic compounds against the SCE (Fc+/0)[24] Compound Potential (V) ... Housane (bicyclo[2.1.0]pentane). *Norbornane (bicyclo[2.2.1]heptane). *Decalin (bicyclo[4.4.0]decane) ... Compounds derived from biogenic precursors during early diagenesis". Geochimica et Cosmochimica Acta. 44 (3): 415-429. Bibcode: ... A polycyclic aromatic hydrocarbon (PAH) is a hydrocarbon-a chemical compound containing only carbon and hydrogen-that is ...

https://en.wikipedia.org/wiki/Polycyclic_aromatic_hydrocarbon

Solubility and compound formation. Metals are insoluble in water or organic solvents unless they undergo a reaction with them. ... Some intermetallic materials e.g. do exhibit metal clusters, reminiscent of molecules and these compounds are more a topic of ... Despite all this progress, the nature of intermetallic compounds and alloys largely remained a mystery and their study was ... One could call these materials metal compounds, but, because materials with metallic bonding are typically not molecular, ...

https://en.wikipedia.org/wiki/Metallic_bonding

"IR-9.2.4.1 Coordination Compounds: Describing the Constitution of Coordination Compounds: Specifying donor atoms: General" (PDF ... Historically important compounds where the ligands are described with hapticity[edit]. *Ferrocene - bis(η5-cyclopentadienyl) ... W(CO)3(PPri3)2(η2-H2 ) - the first compound to be synthesized with a dihydrogen ligand.[8][9] ... Reduction of the 18-VE compound [Ru(η6-C6Me6)2]2+ (where both aromatic rings are bonded in an η6-coordination), results in ...

https://en.wikipedia.org/wiki/Hapticity

Lam, Jørgen (1988). Chemistry and biology of naturally-occurring acetylenes and related compounds (NOARC): proceedings of a ... Housane (bicyclo[2.1.0]pentane). *Norbornane (bicyclo[2.2.1]heptane). *Decalin (bicyclo[4.4.0]decane) ... These compounds are highly bioactive, e.g. as nematocides.[12] 1-Phenylhepta-1,3,5-triyne is illustrative of a naturally ... However, inorganic compounds featuring unsaturation in the form of triple bonds may be denoted by substitutive nomenclature ...

https://en.wikipedia.org/wiki/Alkyne

... is an organic compound with formula C. 10H. 8. It is the simplest polycyclic aromatic hydrocarbon, and is a white ... Bicyclo[6.2.0]decapentaene is a structural isomer with a fused 4-8 ring system[18] and azulene is another, with a fused 5-7 ... Is bicyclo[6.2.0]decapentaene aromatic or antiaromatic?". J. Org. Chem. 50 (15): 2684-2688. doi:10.1021/jo00215a018.. ... Seidell, Atherton; Linke, William F. (1919). Solubility of Inorganic and Organic Compounds (2nd ed.). New York: D. Van Nostrand ...

https://en.m.wikipedia.org/wiki/Naphthalene

Also note: methylcyclopropane is yet a different chemical compound, which is a cycloalkane with the formula C4H8. ... Housane (bicyclo[2.1.0]pentane). *Norbornane (bicyclo[2.2.1]heptane). *Decalin (bicyclo[4.4.0]decane) ... Sisler E.C., Serek M. (2003). "Compounds interacting with the ethylene receptor in plants". Plant Biol. 5 (5): 473-80. doi: ... Synthesis Methods, Complexes and Delivery Methods for the Safe and Convenient Storage, Transport and Application of Compounds ...

https://en.wikipedia.org/wiki/1-Methylcyclopropene

It was first synthesized by Curtius and Gloebel in 1888 and was the first compound containing a peptide bond to be studied by X ... 5-diketopiperazine that possess a unique bicyclo[2.2.2]diazaoctane core ring system and is active against the human colon HCT- ... 2,5-Diketopiperazine, also known as piperazine-2,5-dione and as the cyclodipeptide cyclo(Gly-Gly), is an organic compound and ... In food systems, 2,5-diketopiperazines have been shown to be important sensory compounds contributing to the taste of the final ...

https://en.wikipedia.org/wiki/2,5-Diketopiperazine

... and aza-bicyclo[2,1,1]hexanes". J. Chem. Soc. D. 19: 1167. doi:10.1039/C29710001167. Corey, E. J.; Kang, M. C.; Desai, M. C.; ... many intramolecular reactions that would not occur as an intermolecular reaction between two compounds take place. Examples of ... reactions have been used to synthesize organic compounds with interesting ring systems and topologies. For example, [2+2] ...

https://en.wikipedia.org/wiki/Intramolecular_reaction

Gold-Catalyzed Synthesis of Bicyclo[4.3.0]nonadiene Derivatives via Tandem 6-endo-dig/Nazarov Cyclization of 1,6-Allenynes J. ... Nazarov cyclization tandem catalysed by a gold compound: A 5-endo-dig ring closing reaction was part of a synthesis of (+)- ... chemistry are a series of guidelines outlining the relative favorabilities of ring closure reactions in alicyclic compounds. ...

https://en.wikipedia.org/wiki/Baldwin's_rules

Symmetrical cyclooctynes such as BCN (bicyclo[6.1.0]nonyne) form a single regioisomer upon cycloaddition and may serve to ... and it has also been used in the generation of SPECT imaging compounds. More recently, the use of an oxanorbornadiene was ... The reaction must be selective between endogenous functional groups to avoid side reactions with biological compounds ... imaging agents which must be made quickly with high purity and yield in order to minimize isotopic decay before the compounds ...

https://en.wikipedia.org/wiki/Bioorthogonal_chemistry

The example shown is a facile reaction combining a 1-aza-bicyclo[2.2.1]heptane salt starting material with paraformaldehyde at ... although other silver and copper compounds have been used. This added step allows for more precise control of iminium ion ...

https://en.wikipedia.org/wiki/Aza-Cope_rearrangement

Yu and co-workers reported a unique variant of the reaction that preferentially forms bridged bicyclic compounds. Martin and co ... Cycloaddition of cis-Allene-vinylcyclopropanes to Synthesize the Bicyclo[4.3.1]decane Skeleton". Angewandte Chemie. 56 (30): ...

https://en.wikipedia.org/wiki/Vinylcyclopropane_(5 2)_cycloaddition

Bicyclo Compounds. *Biphenyl Compounds. *Biphenyl Compounds: therapeutic use. *Carbolines. *Carbolines: therapeutic use ...

https://www.mendeley.com/research-papers/clinical-trials-irritable-bowel-syndrome-review/

Bridged Bicyclo Compounds / pharmacology * Calcimycin / pharmacology * Calcium / metabolism * Dose-Response Relationship, Drug ...

https://pubmed.ncbi.nlm.nih.gov/12670876/

Bridged Bicyclo Compounds, Heterocyclic / metabolism * DNA-Binding Proteins / genetics * DNA-Binding Proteins / metabolism* ...

https://pubmed.ncbi.nlm.nih.gov/19490533/

Bridged Bicyclo Compounds, Heterocyclic / therapeutic use* * Drug Approval* * Humans * Leukemia, Lymphocytic, Chronic, B-Cell ...

https://pubmed.ncbi.nlm.nih.gov/27315468/?dopt=Abstract

Bicyclo Compounds / pharmacology. Cyclooxygenase 1 / metabolism. Cyclooxygenase 2 / drug effects, metabolism. Cyclooxygenase 2 ... 0/Bicyclo Compounds; 0/Cyclooxygenase 2 Inhibitors; 0/Hexanoic Acids; 0/Lactones; 0/Membrane Proteins; 0/ONO 8711; 0/Ptgir ...

http://www.biomedsearch.com/nih/Involvement-prostaglandin-E-receptor-EP3/17928639.html

0 (Benzimidazoles); 0 (Bridged Bicyclo Compounds); 0 (Carbamates); 0 (Nitriles); 0 (Pesticide Residues); 0 (Pyrethrins); ... and bioavailability of xenobiotic compounds in soils; data related to sorption capacity are therefore needed for environmental ...

http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=D02.886.675.840

PRIMA-1 has been identified as a compound that restores the transactivation function to mutant p53 and induces apoptosis in ... Aza Compounds / pharmacology*. Bicyclo Compounds, Heterocyclic / pharmacology*. Breast Neoplasms / metabolism*. Cell Line, ... 0/2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one; 0/Antineoplastic Agents; 0/Aza Compounds; 0/Bicyclo Compounds, ... PRIMA-1 has been identified as a compound that restores the transactivation function to mutant p53 and induces apoptosis in ...

http://www.biomedsearch.com/nih/PRIMA-1-cytotoxicity-correlates-with/20946886.html

0 (Actins); 0 (Bridged Bicyclo Compounds, Heterocyclic); 0 (Thiazolidines); 22144-77-0 (Cytochalasin D); EC 3.6.1.- (Myosin ...

http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=D03.633.100.473.231.450

Random copolymer containing derivative of bicyclo [2.2.1] hept-2-ene compound. ... comprising titanium compounds and organoaluminum compounds or vanadium-containing catalysts comprising vanadium compounds and ... Ethylene/bicyclo(2.2.1)hept-2-ene copolymers. US4573994. Dec 7, 1981. Mar 4, 1986. The Johns Hopkins University. Refillable ... 0 556 034 discloses a medical instrument of a material containing a resin of a cyclic olefin compound or a bridged polycyclic ...

http://www.google.com/patents/US6632318?dq=6,049,612

BICYCLO COMPOUNDS/METABOLISM BLUE GREEN ALGAE CHLOROBI CHROMATIUM CYANOBACTERIA DISULFIDES DISULFIDES/ANALYSIS EUKARYOTES ... BICYCLO COMPOUNDS/METABOLISM; CHLOROBI; CHROMATIUM; CYANOBACTERIA; DISULFIDES/ANALYSIS; EUKARYOTIC CELLS; OXIDATION-REDUCTION; ... BACTERIA/CHEMISTRY/METABOLISM; EVOLUTION; GLUTATHIONE/METABOLISM; SULFHYDRYL COMPOUNDS/ANALYSIS; ALGAE, GREEN; BACTERIAL ...

https://ntrs.nasa.gov/search.jsp?R=20040089109&hterms=euglena&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Deuglena

The standard enthalpies of formation of bicyclo compounds. 2. Bicyclo[3.3.1]nonane and bicyclo[3.3.2]decane, J. Chem. Thermodyn ... The Standard Enthalpies of FOrmation of Bicyclo Compounds 2. Bicyclo[3.3.1] nonane and Bicyclo[3.3.2]decane, J, Chem. Thermodyn ... Steele, W.V., The standard enthalpies of formation of bicyclic compounds. IV. Bicyclo[2.2.1]heptan-2-one and bicyclo[2.2.1] ... Steele, W.V., The Standard Enthalpies of Formation of Bicylclic Compounds IV. Bicyclo[2,2,1]heptan-2-one and Bicyclo[2.2.1] ...

https://webbook.nist.gov/cgi/cbook.cgi?Author=Steele%2C+W.V.&Units=CAL&Mask=1A8F

Categories: Bicyclo Compounds, Heterocyclic Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Bicyclo+Compounds,+Heterocyclic&parentid=12823&catid=34825

... can include multi-cyclo compounds such as bicyclo and tricyclo compounds. It should be understood that two bridging bonds will ... For example, the bicyclo compounds that are generally defined by formula (I) can more specifically be represented by formulas ( ... As an example, two R2 bridging bonds can form a bridge across the cyclic amino ring, and thereby create a bicyclo compound. ... Accordingly, it should also be understood that the Z containing moiety can be tethered to the bicyclo compound in the one ring ...

http://www.google.ca/patents/US5786441

Substituted bicyclo [2.2.2] oct/5-ene compounds and their use as cooling agents. April, 2009. Galopin et al. ... Without the sulfites, browning is observed at 55° C. after 1 month of storage, and in the absence of all of the compounds ... Of course, one skilled in this art will select this or these optional additional compounds, and/or their amount, in such manner ... The following are representative non-limiting examples of surface-active wetting agents: compounds of the poloxamer class and ...

https://www.freepatentsonline.com/y2007/0148110.html

CID 17575653 | C8H12O2 | CID 17575653 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

https://pubchem.ncbi.nlm.nih.gov/compound/1R_4S_-bicyclo_2.2.1_heptane-2-carboxylic-acid

https://en.wikipedia.org/wiki/Polyquinane

Compounds having [2.2.1] bicyclo skeleton US6330446B1 (en) * 1998-04-08. 2001-12-11. Oki Electric Industry Co., Ltd.. Velocity- ... Compounds having [2.2.1] bicyclo skeleton US6272344B1 (en) 1998-06-09. 2001-08-07. Nec Corporation. Position registration ...

https://patents.google.com/patent/US7890103B2/en

Bicyclo Compounds [D04.075.080]. *Bicyclo Compounds, Heterocyclic [D04.075.080.875]. *Azabicyclo Compounds [D04.075.080.875.099 ...

https://connects.catalyst.harvard.edu/Profiles/display/Concept/Amdinocillin

1-Amino-2-bicyclo[2.2.1]hept-5-enyl)acetic acid , C9H13NO2 , CID 89235588 - structure, chemical names, physical and chemical ...

https://pubchem.ncbi.nlm.nih.gov/compound/2-_1-Amino-2-bicyclo_2.2.1_hept-5-enyl_acetic-acid

https://en.wikipedia.org/wiki/Bicyclic_molecule

Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating ... which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. ... Disclosed are compounds of Formula A, or a salt thereof: Formula (A), wherein: Het, Q and R1A to R4A are defined herein, ... tetrahydrothiophenyl, tetrahydrothiopyranyl, and the like; and polycyclicheterocyclyl compounds, for example, a bicyclo moiety ...

http://www.sumobrain.com/patents/wipo/Diamino-alkylamino-linked-arylsulfonamide-compounds/WO2018093694A1.html

6 Nomenclature of Unsaturated Compound (Alkenes/Alkynes), Bicyclo compounds 64 Min. 7 Nomenclature of Spiro Compounds, ... 9 Multiple Functional Group Compounds, Aromatic Compounds Nomenclature, Common Names 55 Min. ... 1Classification and Nomenclature of Organic Compound 1 Bonding and Hybridisation of Carbon 55 Min. ... 3 Identification of Functional Groups, Homocyclic and Heterocyclic Compound, Homologous Series 47 Min. ...

https://www.etoosindia.com/courses/neet/500633/n/detail.do

https://en.wikipedia.org/wiki/Dimethyl_fumarate

C. Bicyclo[3.3.0]octane-2,6-dione. (Compound 4; (Note 10).) Diol 3, 12.6 g (0.089 mol), is placed in a 250-ml, three-necked, ... B. Bicyclo[3.3.0]octane-2,6-diol. (Compound 3; (Note 5).) An ice-cooled aqueous 10% solution of sodium hydroxide (100 mL) is ... A. 2,6-Diacetoxybicyclo[3.3.0]octane. (Compound 2; (Note 1) and (Note 2).) An ovendried. 1-L round-bottomed flask, equipped ... Bicyclo[3.3.0]octane-2,6-dione has been known since 1934,10 but extant procedures for large-scale multigram synthesis of this ...

http://www.orgsyn.org/demo.aspx?prep=CV8P0043

3 naming of compound having only one functional group 68 Min. 4 Naming of poly function group,cyclo,bicyclo compound,spiro comp ...

https://www.etoosindia.com/courses/jee/19210/jee-complete-organic-chemistry-for-main-and-advanced-by-PO-sir/detail.do

Spiro{bicyclo[4.2.0]octa-1,3,5-triene-7,2′-[1,3]-dioxolan}-8-one. Encyclopedia of Reagents for Organic Synthesis. Gary W. ...

http://onlinelibrary.wiley.com/compoundRecord/overview?doi=10.1002%252F047084289X.rd078.pub2&xmlid=rd078-eo-c00158

Bicyclo and Aromatic Compounds Class 11 Notes , EduRev search giving you solved answers for the same. Stereoisomers - Compounds ... IUPAC accepted their common trivial names e.g., The document Naming Alicyclic, Spiro, Bicyclo and Aromatic Compounds Class 11 ... Naming Alicyclic Spiro Bicyclo And Aromatic Compounds, Pdf Nomenclature Of Regular Double Strand Ladder And Spiro, 2 5 Naming ... Nomenclature Of Organic Compounds Pdf Alkane Functional, The Correct Iupac Name Of The Spiro Compound Br Img Src, Pdf ...

https://itb-entertainment.com/site/article.php?550a0b=naming-spiro-compounds-practice-problems-pdf

4 indent ) 2,2,1-bicyclo 121 .. (2 indent ) Cyclopentyl in acid moiety (e.g., prostaglandins, etc.) ... 4 indent ) Epoxy compound, or metal, utilized 354 .. (2 indent ) Containing polycyclo ring system having alicyclic ring as one ... 1 indent ) Compounds having the group -C(=X)-X-nX-, wherein the Xs may be the same or diverse chalcogens, nX is a divalent ... 1 indent ) Peroxynitrate esters (i.e., compounds having the -O-O-N(=O)(=O) group bonded directly to carbon, which carbon may be ...

https://www.uspto.gov/web/patents/classification/uspc560/isched560.htm

... about INDIUM COMPOUNDS. Search and download thousands of Swedish university dissertations. Full text. Free. ... 3. Synthesis of Spiro-bicyclo[2.2.2]Octane Derivatives Towards the Development of Paclitaxel Mimetics. University dissertation ... Search for dissertations about: indium compounds. Showing result 1 - 5 of 9 swedish dissertations containing the words indium ... Abstract : Volatile organic compounds (VOCs) in the indoor air have adverse effects on the dwellers residing in a building or a ...

https://www.dissertations.se/about/indium+compounds/

Pino, J.A.; Marbot, R.; Bello, A., Volatile compounds of Psidium salutare (H.B.K.) Berg. fruit, J. Agric. Food Chem., 2002, 50 ... 7-Dimethyl-2-methylen-bicyclo(2,2,1)heptane; 7,7-Dimethyl-2-methylenebicyclo[2.2.1]heptane; Fenchene, Bicyclo[2.2.1]heptane,2- ... Helmig, D.; Klinger, L.F.; Guenther, A.; Vierling, L.; Geron, C.; Zimmerman, P., Biogenic volatile organic compound emissions ( ... Meynier, A.; Novelli, E.; Chissolinim, R.; Zanardi, E.; Gandemer, G., Volatile compounds of commercial Milano salami, Meat Sci. ...

https://webbook.nist.gov/cgi/cbook.cgi?ID=C471841&Units=CAL&Mask=FFFF

The main focus of this thesis concerns the diastereoselective synthesis of heterocyclic compounds using main group elements as Lewis acid catalysts. (dissertations.se)
Study on cyclization reactions of heterocyclic compounds bearing ethynyl and formyl groups in close proximity to each other. (vu.lt)
Heterocyclic compounds for producing dyes are classified in subclass C09B . (uspto.gov)

Fowden, L.: The Occurrence and Metabolism of Carbon-Halogen Compounds. (springer.com)

Three modes of ring junction are possible for a bicyclic compound: In spirocyclic compounds, the two rings share only one single atom, the spiro atom, which is usually a quaternary carbon. (wikipedia.org)
Fused and bridged bicyclic compounds get the prefix bicyclo, whereas spirocyclic compounds get the prefix spiro. (wikipedia.org)
The Correct Iupac Name Of The Spiro Compound Br Img Src. (itb-entertainment.com)
Monospiro compounds consisting of only two alicyclic rings as components are named by placing "spiro" before the name of the normal acyclic hydrocarbon of the same total number of carbon atoms. (itb-entertainment.com)

WO 97/6168 forms prior art under Art 54(3) (4) EPC and discloses the use of bis-diazo compounds in the synthesis of diaza bicyclo compounds. (patent-de.com)

Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. (elsevier.com)
The rapid synthesis of bicyclo[ m . n .1]alkanone cores possessing quaternary carbon centers adjacent to a bridged ketone represents a significant synthetic challenge. (beilstein-journals.org)

Wine is an alcoholic solution with a high variety of dissolved substances such as sugars, acids, alcohols, phenolic compounds, nitrogen compounds, macromolecular materials, minerals, and a number of volatile organic compounds that have great influence on sensory and variety characteristics of wine. (hindawi.com)
As aroma compounds are intrinsically volatile substances, most of the compounds should be determined by gas chromatography with the exception for thermolabile substances. (hindawi.com)

Synthesis, structural and association studies of chiral supramolecular polycyclic tectones based on bicyclo[3.3.1]nonane framework. (vu.lt)
The bicyclo[3.3.1]nonane system adopts a boat-chair conformation. (eurekamag.com)

The simplest polyquinane is the bicyclic compound bicyclo[3.3.0]octane. (wikipedia.org)
A bicyclic compound can be carbocyclic (all of the ring atoms are carbons), or heterocyclic (the rings atoms consist of at least two elements), like DABCO. (wikipedia.org)

Overall, the invention provides the chemistry for the compounds and for the processes to prepare compounds derived from 1,5-diazacyclooctanes. (patents.com)
To name bicyclic compounds based on the International Union of Pure and Applied Chemistry (IUPAC) system of nomenclature, start with the term "bicyclo. (reference.com)
Lithium Phenylethynolate and Its Reaction with Carbony1 Compounds to Give p-Lactones By Ulrich Schollkopf and lnga Hoppe'] While enolates ( I ) have numbered among the most important reagents of organic chemistry for more than a century, ynolates (2) have hitherto remained unknown although their chemistry should certainly be no less interesting than that of the former class of compounds. (docme.ru)

In this work, we describe the development of a more general, lipase-catalyzed double-acetylation reaction, which could successfully resolve an earlier precursor, 4-(tert-butyldiphenylsilamethoxy)-1-(hydroxymethyl)bicyclo[3.1.0]hexan-2-ol [(±)7], into enantiomerically pure (+)-diacetate 8 and (-)-monoacetate 9. (elsevier.com)
There are prepared reaction products of a. 4,4-bis-(hydroxymethyl)-cyclohexene compounds of the formula ##EQU1## where R1, R2 and R4 are the same or different and are hydrogen, methyl or phenyl and there is also present either (1) X as the bridging member methylene or ethylene or (2) X is absent and. (google.ca)

Krebs, H.C.: Recent Developments in the Field of Marine Natural Products with Emphasis on Biologically Active Compounds. (springer.com)

After 1981 researchers all over the world have focused on marine-derived Phoma for their bioactive compounds. (springer.com)
In addition, this review summarizes the novel bioactive compounds derived from marine Phoma and their biological activities. (springer.com)
Study for bioactive compounds in leaves yielded heneicosanoic acid (25.22), bicyclo [4.1.0] hepta-2, 4-dien (27.41), octadecanoic acid (CAS), stearic acid (31.19) and octadeca-9, 12-dienoic acid (32.02). (stuartxchange.com)

Nonaromatic compounds are hydrocarbon compounds that do not have a conjugate ring system, such as naphthalene, benzene or imidazole. (reference.com)
The 2D-GCxGC/TOFMS results showed that various types of hydrocarbon compounds (aliphatics, aromatics, cyclics olefins, and phenanthrene) were available in the liquid hydrocarbon fuel. (rsc.org)

Palladium-Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds. (docme.ru)
DOI: 10.1002/anie.200900013 Palladium Catalysis Palladium-Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds Anne Brennfhrer, Helfried Neumann, and Matthias Beller* Keywords: aryl halides · carbon monoxide · carbonylation · homogeneous catalysis · palladium Dedicated to Professor Armin de Meijere on the occasion of his 70th birthday Angewandte Chemie 4114 www.angewandte.org 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Angew. (docme.ru)
1] This Review summarizes the recent work in the area of palladium-catalyzed carbonylation reactions of aryl halides and related compounds. (docme.ru)
In particular, coupling reactions of aryl-X compounds to give carboxylic acid derivatives, aldehydes, and ketones are described. (docme.ru)

With this reaction, compounds with bicyclo skeletons can be synthesized, e.g. a diester with a norbornene (bicyclo[2.2.1]heptene) skeleton from dimethyl fumarate and cyclopentadiene. (wikipedia.org)

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. (freepatentsonline.com)
Biocidal, pest attractant, or plant growth regulatory activity of chemical compounds or preparations is further classified in subclass A01P (this subclass does only exist in IPC).Therapeutic activity of chemical compounds is further classified in subclass A61P . (uspto.gov)

Carbonylation of Aromatic (Pseudo)Halides to Carboxylic Acid Derivatives The palladium-catalyzed carbonylation of aryl X compounds to give carboxylic acid derivatives is becoming a valuable tool in organic synthesis. (docme.ru)
2-exo-Amino-6-endo-(methylthio)bicyclo[2.2.1]heptane-2-endo-carboxylic acid (lc) was synthesized by amination of the lithium enolate of methyl 6-endo-(methylthio)bicyclo[2.2.1]heptane-2-ercdo-carboxylate with 0-(mesitylenesulfonyl)hydroxylamine followed by hydrolysis. (elsevier.com)
The structure is compared both with 6-exo-(methylthio)bicyclo[2.2.1]heptane-2-endo-carboxylic acid (3) and the HBr salt of 2-exo-aminobicyclo[2.2.1]heptane-2-endo-carboxylic acid (2). (elsevier.com)

Disclosed are compounds of Formula A, or a salt thereof: Formula (A), wherein: Het, Q and R1A to R4A are defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. (sumobrain.com)
said compound is unsubstituted or substituted with a halo, alkyl, alkoxy, or combinations thereof. (google.com.au)

Engvild, K.C.: Chlorine-Containing Natural Compounds in Higher Plants. (springer.com)
Amadis Chemical Co., Ltd. provides Pharmaceutical Intermediates, Active Pharmaceutical Ingredients (APIs) and Natural Compounds. (chemicalregister.com)

For example, decalin is named bicyclo[4.4.0]decane. (wikipedia.org)

For example, bicyclo[1.1.0]butane is typically called simply bicyclobutane. (wikipedia.org)

Selection of sampling techniques, sample preparation, determinants separation, detection, and quantification, will be essential and crucial for the proper chemical characterization of aroma-related compounds. (hindawi.com)
Characterization of 9 slowly dissociated opioid ligands azabicyclononances compounds to mu, delta, and kappa receptors]. (semanticscholar.org)

Stereoisomers - Compounds that have the same molecular formula and the same connectivity, but different arrangement of the atoms in 3-dimensional space. (itb-entertainment.com)
There were 71 low molecular weight organic compounds observed, two of which remained unidentified. (ijpsonline.com)
The low-molecular weight organic compounds (LMWOC) of the extracts were defined by methods of GC/MS with the help of Shimadzu GC/MS (QP-5050А, Shimadzu, Japan) equipped with the software Class 5000 and chromato-mass spectrometer TRACE DSQ II (Thermo Electron Corporation) with quadrupole mass analyser. (ijpsonline.com)

Cover compounds containing one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system, with or without other non-condensed hetero rings. (uspto.gov)

For example, norbornane, also known as bicyclo[2.2.1]heptane, can be viewed as a pair of cyclopentane rings each sharing three of their five carbon atoms. (wikipedia.org)
Addition of the prefix bicyclo gives the total name bicyclo[2.2.1]heptane. (wikipedia.org)

Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating cough, itch, acute pain and neuropathic pain disorders using the same. (sumobrain.com)
Several methods exist for the laboratory synthesis of dimethyl fumarate, with reported methods alkene isomerization of dimethyl maleate , and Fischer esteriﬁcation of fumaric acid Dimethyl fumarate is an ester and an α,β-unsaturated electrophilic compound which can quickly undergo Michael additions with nucleophiles. (wikipedia.org)
Preparations for medical, dental, or toilet purposes or methods of using compounds for the same purposes are classified in subclass A61K . (uspto.gov)
Bringing together the research and methods of leading scientists in the fluorine field, Efficient Preparations of Fluorine Compounds is the definitive manual to creating, and understanding the reaction mechanisms integral to a wide variety of fluorine compounds. (wiley.com)

Phenolic compounds profile yielded ellagic acid (4.13 min), catechol (3.59 min), gallic acid (4.12 min) and catechin (7.41 min). (stuartxchange.com)

As a α,β-unsaturated electrophilic compound, dimethyl fumarate is rapidly attacked by the detoxifying agent glutathione (GSH) in a Michael addition reaction. (wikipedia.org)
A phase transfer catalyst facilitates the reaction in a heterogeneous system between general organic compounds that are soluble in organic solvents and com. (reference.com)
In order to solve this issue, we assumed that bicyclo[3.3.1]nonenone scaffolds can be directly obtained through an intermolecular Diels-Alder reaction/Au(I)-catalyzed 6- endo-dig carbocyclization ( Scheme 3 ). (beilstein-journals.org)

A process for producing compounds represented by general formulae (III) and (IV), which are useful as intermediates for the production of amino acid derivatives which have a renin inhibitory activity and are useful as a hypotensive, ster. (sumobrain.com)

These results indicate that in some cellular context, the cell sensitivity to PRIMA-1 could depend on the abolition of a gain-of-function activity of the mutated p53, through a protein degradation pathway specifically induced by this compound. (biomedsearch.com)

Natural chlorine-, bromine-, iodine-, and fluorine-containing organic chemical compounds are abundant on our planet. (springer.com)
Resembling a spirit from a chemical netherworld, fluorine is highly reactive, difficult to handle, yet very versatile as a reagent-with the power to form compounds with almost any other element. (wiley.com)
The only chemical resource of its kind, Efficient Preparations of Fluorine Compounds -from its first experiment to its last-is a unique window into the centuries old science of fluorine and the limitless universe of fluorine-based compounds. (wiley.com)
Methodology: Air-dried and pulverized leaves were hydrodistilled in a Clevenger-type apparatus to obtained pale yellow volatile oil whose chemical constituents was analyzed by GC and GC/MS. Results: A total of sixty compounds were identified, amounting to 98.9%of the total oil contents. (bvsalud.org)

The oil is then distilled under reduced pressure (74-79°C at 0.06 mm) to yield analytically pure bicyclo[3.3.0]octane-2,6-dione , 4 ( 6.4-7.1 g , 52-58% ) as a white crystalline solid, mp 45-46°C (lit. (orgsyn.org)

The antiproliferative effect of these compounds were determined against human leukemia, K562 (chronic myelogenous leukemia) and CEM (T-cell leukemia) cells using trypan blue and MTT assay, and the SAR associated with the position of N-terminal substituents in diazaspiro bicyclo hydantoin have also been discussed. (springer.com)

The position and number of substituents in benzyl group attached to N− 8 of diazaspiro bicyclo hydantoin nucleus interacted selectively with specific targets leading to the difference of biochemical and pharmacological effects. (springer.com)

HS-SPME shows a much higher sensitivity to volatile aromatic compounds and semivolatile than other conventional headspace techniques [ 3 ]. (hindawi.com)
Therefore, compounds with molecules containing one or more of a non-aromatic rings are collectively categorized as nonaromatic compounds. (reference.com)

It has been observed that these compounds displayed strong, moderate and weak cytotoxic activities. (springer.com)
Interestingly, compounds having electron withdrawing groups at third and fourth position of the phenyl ring displayed selectively cytotoxic activities to both the cell lines tested with IC 50 value lower than 50 μM. (springer.com)

A polyquinane polycyclic compound consisting of fused five-membered hydrocarbon rings. (wikipedia.org)

Heterocycles incorporating elements other than C, H, halogen, N, O, S, Se or Te are classified in subclass C07F , but only if the metal-containing compound has a metal carbon bond or if the metal is attached to at least two different ligands. (uspto.gov)
Specifically, infrared light which has been generated by a laser is first absorbed by a radiation absorber (e.g., an infrared absorbing material such as an infrared dye, black alumina, or carbon black) and then converted to heat to decompose the energetic compound. (patent-de.com)

The bicyclo[3.1.0]hexane scaffold can lock the conformation of a carbocyclic nucleoside into one of the two antipodal (north or south) conformations typical of conventional nucleosides that normally exist in a rapid, two-state equilibrium in solution. (elsevier.com)

The compounds are represented by compounds of formula (1.0) and their pharmaceutically acceptable salts and solvates. (sumobrain.com)
The only exception to this requirement is that the compounds may contain metal atoms, but only as the cations of heterocyclic organic acid salts, alcoholates, phenolates or mercaptides, or as chelating atoms, e.g. in porphyrins. (uspto.gov)
Salts, chelates, alcoholates (except Ti/Zr), phenates involving a single ligand are classified as the parent compound (metal containing porphyrin C07D 487/22 ). (uspto.gov)
Examples of such energetic compounds include diazonium salts as well as compounds containing azo, azido, nitrato, and nitramino groups, such as nitrocellulose, polyvinyl nitrates, and the like. (patent-de.com)

Nonaromatic compounds do not have a loop for pi electron. (reference.com)
In accordance with the present invention, the sensitivity of laser induced thermal imaging systems can be increased by using diazo compounds that contain at least one electron withdrawing functional group adjacent the diazo substituent capable of stabilizing the diazo substituent (i.e., the =N + =N - substituent). (patent-de.com)

Liquid hydrocarbons as fuel were found to be appropriate for use in petrol and diesel engines and they were found to be a good source of organic compounds/petrochemicals. (rsc.org)

Organic compounds containing at least one heterocyclic ring, and with no ring comprising a steroid, saccharide or peptide moiety. (uspto.gov)
Succinimidyl ester/NHS functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. (sigmaaldrich.com)

In class C07 , the last place priority rule is used, i.e. in the absence of an indication to the contrary, a compound is classified in the last appropriate subclass. (uspto.gov)
Similarly, compounds containing saccharide radicals are classified in subclass C07H , and heterocyclic steroids are classified in subclass C07J . (uspto.gov)
This subclass is a structure-oriented entry for the compounds themselves and does not cover the application or use of the compounds under the subclass definition. (uspto.gov)

The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain coding molecules that encode the. (patents.com)
A compound of formula (I). The present invention relates to therapeutically active .beta. (patents.com)
In particular, this invention pertains to the method of improving sensitivity in laser induced thermal imaging using diazo compounds. (patent-de.com)

In fused bicyclic compounds, two rings share two adjacent atoms. (wikipedia.org)
In bridged bicyclic compounds, the two rings share three or more atoms, separating the two bridgehead atoms by a bridge containing at least one atom. (wikipedia.org)
The root of the compound name depends on the total number of atoms in all rings together, possibly followed by a suffix denoting the functional group with the highest priority. (wikipedia.org)
When naming simple fused bicyclic compounds, the same method as for bridged bicyclic compounds is applied, except the third path between the two bridgehead atoms now consists of zero atoms. (wikipedia.org)

Volatile organic compounds (VOCs) in the indoor air have adverse effects on the dwellers residing in a building or a vehicle. (dissertations.se)
Application of headspace solid-phase microextraction (HS-SPME) coupled with high-resolution gas chromatographic (HRGC) analytical system was studied for detection and identification of volatile compounds in wines. (hindawi.com)
This is a useful technique for obtaining fingerprints of food flavors, although the most obvious benefit is the ability to isolate and concentrate volatile compounds without interference from matrix components [ 1 ]. (hindawi.com)
SPME is the suitable technique for volatile compounds in wine. (hindawi.com)
The aim of this work was to apply the GC-MS technique combined with automatic headspace (HS) SPME to the identification of minor volatile compounds in wine selecting the best fiber for this purpose. (hindawi.com)

Diseases2

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Phenomena and Processes10

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture3

Information Science2

Health Care2

Publication Characteristics1

Drug-protein binding and blood-brain barrier permeability. (1/549)

Influence of a new antiulcer agent, ammonium 7-oxobicyclo (2, 2, 1) hept-5-ene-3-carbamoyl-2-carboxylate (KF-392) on gastric lesions and gastric mucosal barrier in rats. (2/549)

Isolation and structural determination of a novel bicyclic taxane diterpene from needles of the Chinese yew, Taxus mairei. (3/549)

Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. (4/549)

Endothelium-derived contracting factor in carotid artery of hypertensive Dahl rats. (5/549)

Fatty acid translocase/CD36 mediates the uptake of palmitate by type II pneumocytes. (6/549)

Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1. (7/549)

Cross-resistance with dieldrin of a novel tricyclic dinitrile GABA receptor antagonist. (8/549)

Bicyclo Compounds

Bicyclo Compounds, Heterocyclic

Octanes

Imides

Cyclization

Indole Alkaloids

Molecular Structure

Cycloaddition Reaction

Stereoisomerism

Adenosine A3 Receptor Agonists

Adenosine A3 Receptor Antagonists

Prenylation

Methyl n-Butyl Ketone

Norbornanes

Rhodium

Cyclooctanes

Anti-Anxiety Agents

Receptor, Adenosine A3

Ketones

Nucleosides

Cyclopropanes

Hexanes

Magnetic Resonance Spectroscopy

Spectrophotometry, Infrared

Bornanes

Molecular Conformation

Structure-Activity Relationship

Catalysis

Models, Molecular

Sulfur Compounds

Cycloparaffins

Patents as Topic

Solvents

Lab-On-A-Chip Devices

Complement C1

Complement C2

Benz(a)Anthracenes

Phototrophic Processes

Technical Report

Glutathione

United States National Aeronautics and Space Administration

Glutathione Reductase

Glutathione Transferase

Cataloging

Polymers

Amines

Carbon

Programming, Linear

Hydrogen

Vitiligo

Skin Lightening Preparations

Skin Pigmentation

Dermatologic Agents

Melanins

Hypopigmentation

Keratolytic Agents

Drug-protein binding and blood-brain barrier permeability. (1/549)

Influence of a new antiulcer agent, ammonium 7-oxobicyclo (2, 2, 1) hept-5-ene-3-carbamoyl-2-carboxylate (KF-392) on gastric lesions and gastric mucosal barrier in rats. (2/549)

Isolation and structural determination of a novel bicyclic taxane diterpene from needles of the Chinese yew, Taxus mairei. (3/549)

Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. (4/549)

Endothelium-derived contracting factor in carotid artery of hypertensive Dahl rats. (5/549)

Fatty acid translocase/CD36 mediates the uptake of palmitate by type II pneumocytes. (6/549)

Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1. (7/549)

Cross-resistance with dieldrin of a novel tricyclic dinitrile GABA receptor antagonist. (8/549)

BICYCLO(2.2.2)OCTANE-2-METHYLAMINE, N,N-DIMETHYL-3-PHENYL-, HYDROCHLORIDE, (E)- | C17H26ClN - PubChem

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CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors | PNAS

Piperazine,1-bicyclo[3.1.0]hex-3-yl-4-methyl-,(1-alpha-,3-ba-,5-alpha-)-(9ci) - Alfa Chemistry

3-bicyclo[2.2.1]hept-2-yl-benzene-1,2-diol | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY

3-[(1S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |...

procymidone (Sumilex) Proposed Tolerance 3/94

DRUG SYNTHESIS INTERNATIONAL: November 2015

DRUG SYNTHESIS INTERNATIONAL: 2015

4-Nitrophenyl bicyclo[4.1.0]heptane-7-carboxylate | C14H15NO4 - PubChem

1-(5-(hydroxymethyl)bicyclo(3.1.0)hex-3-en-2-yl)-5-methyl-1,3-dihydropyrimidine-2,4-dione Summary Report | CureHunter

PQR | [(1s,2r,3s,4r,5s)-2-(6-amino-2-chloro-purine-1,3,7-triium-9-yl)-3,4-dihydroxy-5-bicyclo[3.1.0]hexanyl]methyl dihydrogen...

PQR | 2-[(1s,2r,3s,4r,5r)-2-(6-amino-2-chloro-purine-1,3,7-triium-9-yl)-3,4-dihydroxy-5-bicyclo[3.1.0]hexanyl]ethylphosphonic...

Chemical Database: 7-Oxabicyclo(4.1.0)hept-3-ene, 2,5-dibromo-, trans- (EnvironmentalChemistry.com)

2-Methoxy-6-(5,6,6-trimethyl-2-bicyclo[2.2.1]heptanyl)phenol - Alfa Chemistry

1-(4-fluorophenyl)bicyclo[1.1.1]pentan-3-amine