AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesNamed GroupsHealth Care
BethanecholBethanechol CompoundsParasympathomimeticsMuscarinic AgonistsTropicamideAgeusiaParasympatholyticsPentagastrinAtropineGastric AcidReceptors, MuscarinicMuscarinic AntagonistsPirenzepineMetiamideCholinergic AgentsReceptor, Muscarinic M3AmylasesUrinary RetentionBronchial SpasmGenitalia, FemaleTriacetinPharmacistsAdministration, OralDrug Administration ScheduleStomachParasympathetic Nervous SystemEsophagogastric JunctionUrinationUrinary BladderAnti-Inflammatory Agents, Non-SteroidalAcetaminophenMuscle Relaxants, CentralPainPhysician-Patient RelationsCarcinoma, Pancreatic DuctalAdenocarcinomaPancreatic NeoplasmsSalivation
Bethanechol
A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
Bethanechol Compounds
Parasympathomimetics
Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.
Muscarinic Agonists
Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
Tropicamide
One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.
Ageusia
Complete or severe loss of the subjective sense of taste, frequently accompanied by OLFACTION DISORDERS.
Parasympatholytics
Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.
Pentagastrin
A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.
Atropine
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
Gastric Acid
Hydrochloric acid present in GASTRIC JUICE.
Receptors, Muscarinic
One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.
Muscarinic Antagonists
Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.
Pirenzepine
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Metiamide
A histamine H2 receptor antagonist that is used as an anti-ulcer agent.
Cholinergic Agents
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.
Receptor, Muscarinic M3
A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOOTH MUSCLES.
Amylases
A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.
Urinary Retention
Inability to empty the URINARY BLADDER with voiding (URINATION).
Bronchial Spasm
Spasmodic contraction of the smooth muscle of the bronchi.
Genitalia, Female
The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.
Triacetin
A triglyceride that is used as an antifungal agent.
Pharmacists
Those persons legally qualified by education and training to engage in the practice of pharmacy.
Administration, Oral
The giving of drugs, chemicals, or other substances by mouth.
Drug Administration Schedule
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Stomach
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Parasympathetic Nervous System
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
Esophagogastric Junction
The area covering the terminal portion of ESOPHAGUS and the beginning of STOMACH at the cardiac orifice.
Urination
Discharge of URINE, liquid waste processed by the KIDNEY, from the body.
Urinary Bladder
A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Acetaminophen
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Physician-Patient Relations
The interactions between physician and patient.
Carcinoma, Pancreatic Ductal
Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Salivation
The discharge of saliva from the SALIVARY GLANDS that keeps the mouth tissues moist and aids in digestion.

Muscarinic stimulation of calcium/calmodulin-dependent protein kinase II in isolated rat pancreatic acini. (1/144)

AIM: To study whether M3 receptor occupation would lead to activation of calcium/calmodulin-dependent protein kinase II (CaM kinase II). METHODS: In this study, we isolated rat pancreatic acini by collagenase digestion; measured the Ca2+/calmodulin-independent activity of autophosphorylated form of the CaM kinase II both before and after stimulation of the acini with muscarinic secretagogue bethanechol (Bet). RESULTS: Bet stimulated the activation of, or generation of Ca(2+)-independent activity of, this kinase, in a concentration (0.0001-1 mmol.L-1) and time (5-300 s)-dependent manner; with Bet of 100 mumol.L-1, Ca(2+)-independent activity increased from an unstimulated level of 4.5 +/- 0.3 (n = 4) to 8.9 +/- 1.3 (n = 4, P < 0.05) at 5 s. Another Ca2+ mobilizing secretagogue cholecystokinin (CCK) also activated the kinase; at 1 mumol.L-1, CCK increased Ca(2+)-independent kinase activity to 12.9 +/- 0.5 (n = 6, P < 0.05). Vasoactive intestinal peptide (VIP) at 1 mumol.L-1 did not produce significant Ca(2+)-independent kinase activity (from control 3.90 +/- 0.28 to 4.53 +/- 0.47, n = 6, P > 0.05). Atropine completely blocked Bet activation of the kinase. CONCLUSION: CaM kinase II plays a pivotal role in digestive enzyme secretion, especially during the initial phase of amylase secretion.  (+info)

Myogenic mechanism for peristalsis in the cat esophagus. (2/144)

A myogenic control system (MCS) is a fundamental determinant of peristalsis in the stomach, small bowel, and colon. In the esophagus, attention has focused on neuronal control, the potential for a MCS receiving less attention. The myogenic properties of the cat esophagus were studied in vitro with and without nerves blocked by 1 microM TTX. Muscle contraction was recorded, while electrical activity was monitored by suction electrodes. Spontaneous, nonperistaltic, electrical, and mechanical activity was seen in the longitudinal muscle and persisted after TTX. Spontaneous circular muscle activity was minimal, and peristalsis was not observed without pharmacological activation. Direct electrical stimulation (ES) in the presence of bethanechol or tetraethylammonium chloride (TEA) produced slow-wave oscillations and spike potentials accompanying smooth muscle contraction that progressed along the esophagus. Increased concentrations of either drug in the presence of TTX produced slow waves and spike discharges, accompanied by peristalsis in 5 of 8 TEA- and 2 of 11 bethanechol-stimulated preparations without ES. Depolarization of the muscle by increasing K(+) concentration also produced slow waves but no peristalsis. We conclude that the MCS in the esophagus requires specific activation and is manifest by slow-wave oscillations of the membrane potential, which appear to be necessary, but are not sufficient for myogenic peristalsis. In vivo, additional control mechanisms are likely supplied by nerves.  (+info)

Cholinergic effects on human gastric motility. (3/144)

BACKGROUND: Cholinergic regulation of chronotropic (frequency) and inotropic (force) aspects of antral contractility and how these impact on gastric emptying are not well delineated. AIMS: To determine the effects of cholinergic stimulation and inhibition on myoelectric, contractile, and emptying parameters of gastric motility. METHODS: Ten normal subjects underwent three studies each, using simultaneous electrogastrography (EGG), antroduodenal manometry, and gastric emptying with dynamic antral scintigraphy (DAS). After 30 minutes of baseline fasting manometry and EGG, subjects received saline intravenously, atropine (0.6 mg then 0.25 mg/hour intravenously), or bethanechol (5 mg subcutaneously). This was followed by another 30 minutes' recording and by three hours of postprandial recording after ingestion of a technetium-99m labelled solid meal. RESULTS: During fasting, atropine decreased, whereas bethanechol increased, the antral manometric motility index and EGG power. Postprandially, atropine decreased the amplitude of antral contractions by DAS, decreased the postprandial antral manometric motility index, and slowed gastric emptying. Atropine caused a slight increase in postprandial frequency of antral contractions by DAS and gastric myoelectrical activity by EGG. Bethanechol slightly increased the amplitude, but slightly decreased the frequency of antral contractions by DAS and decreased the frequency of gastric myoelectrical activity by EGG, with no significant increase in the motility index or gastric emptying. CONCLUSIONS: Cholinergic antagonism with atropine reduces antral contractility and slows gastric emptying. Cholinergic stimulation with bethanechol increases antral contractility, but decreases the frequency of antral contractions, without altering the antral motility index or gastric emptying.  (+info)

Time course of isolated rat fundus response to muscarinic agonists: a measure of intrinsic efficacy. (4/144)

The establishment of a dose-response relationship and its quantification is the usual procedure for analysing drug action on an isolated organ. However, the time course of the effect seems to be an inherent characteristic of the agonist which produces it. In our study, we have analyzed the time-response curves of four cholinergic agonists (acetylcholine, methacholine, carbachol and bethanechol) which produce tonic contractions of the isolated rat gastric fundus. The order of affinity of agonists to muscarinic receptors on the rat fundus were carbachol > bethanechol > methacholine > acetylcholine (K(A) values: 46 +/- 12, 84 +/- 21, 380 +/- 110 and 730 +/- 120 nM, respectively). The effective concentrations which produced 60% of the maximal response (EC60) were used for establishing the time-response curves. The time-response curves were also recorded after partial alkylation of muscarinic receptors with phenoxybenzamine, after exposure of the isolated rat fundus to physostigmine and after addition of supramaximal concentrations of the agonists. The experimental time-response curve for acetylcholine was on the extreme left, followed by curves for methacholine, bethanechol and carbachol, respectively. Phenoxybenzamine and supramaximal doses of the agonists did not change the order of response development in time, but supramaximal doses shifted all curves to the left and phenoxybenzamine shifted all time-response curves to the right. Only physostigmine shifted the time-response curve for methacholine to the right. The results of our study suggest that the response rate of the isolated rat gastric fundus to cholinergic agonists depends on the intrinsic activity of these agents, but not on their affinity for muscarinic receptors.  (+info)

Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects. (5/144)

BACKGROUND: Topical nitrates lower anal sphincter pressure and heal anal fissures, but a majority of patients experience headache. The internal anal sphincter has a calcium dependent mechanism to maintain tone, and also receives an inhibitory extrinsic cholinergic innervation. It may therefore be possible to lower anal sphincter pressure using calcium channel blockers and cholinergic agonists without side effects. AIMS: To investigate the effect of oral and topical calcium channel blockade and a topical cholinomimetic on anal sphincter pressure. METHODS: Three studies were conducted, each involving 10 healthy volunteers. In the first study subjects were given oral 60 mg diltiazem or placebo on separate occasions. They were then given diltiazem once or twice daily for four days. In the second and third studies diltiazem and bethanechol gels of increasing concentration were applied topically to lower anal pressure. RESULTS: A single dose of 60 mg diltiazem lowered the maximum resting anal sphincter pressure (MRP) by a mean of 21%. Once daily diltiazem produced a clinically insignificant effect but a twice daily regimen reduced anal pressure by a mean of 17%. Diltiazem and bethanechol gel produced a dose dependent reduction of the anal pressure; 2% diltiazem produced a maximal 28% reduction, and 0.1% bethanechol a maximal 24% reduction, the effect lasting three to five hours. CONCLUSIONS: Topical diltiazem and bethanechol substantially reduce anal sphincter pressure for a prolonged period, and represent potential low side effect alternatives to topical nitrates for the treatment of anal fissures.  (+info)

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. I. Use of chlorotetracycline as fluorescent probe. (6/144)

Stimulus-secretion coupling in pancreatic exocrine cells was studied using dissociated acini, prepared from mouse pancreas, and chlorotetracycline (CTC), a fluorescent probe which forms highly fluorescent complexes with Ca2+ and Mg2+ ions bound to membranes. Acini, preloaded by incubation with CTC (100 microM), displayed a fluorescence having spectral properties like that of CTC complexed to calcium (excitation and emission maxima at 398 and 527 nm, respectively). Stimulation with either bethanechol or caerulein resulted in a rapid loss of fluorescence intensity and an increase in outflux of CTC from the acini. After 5 min of stimulation, acini fluorescence had been reduced by 40% and appeared to be that of CTC complexed to Mg2+ (excitation and emission maxima at 393 and 521 nm, respectively). The fluorescence loss induced by bethanechol was blocked by atropine and was seen at all agonist concentrations that elicited amylase release. Maximal fluorescence loss, however, required a bethanechol concentration three times greater than that needed for maximal amylase release. In contrast, acini preloaded with ANS or oxytetracycline, probes that are relatively insensitive to membrane-bound divalent cations, displayed no secretagogue-induced fluorescence changes. These results are consistent with the hypothesis that CTC is able to probe some set of intracellular membranes which release calcium during secretory stimulation and that this release results in dissociation of Ca(2+)-complexed CTC.  (+info)

Signaling mechanisms for muscarinic receptor-mediated coronary vasoconstriction in isolated rat hearts. (7/144)

Signaling mechanisms for muscarinic receptor-mediated vasoconstriction in coronary resistance arteries were studied in potassium-arrested isolated rat hearts perfused at a constant flow rate. The cholinergic agonist bethanechol was given by bolus injection or constant infusion. Perfusion pressure was monitored as an indicator of coronary vascular resistance. Bolus injection of bethanechol evoked a phasic vasoconstriction in a dose-dependent manner, whereas infusion of bethanechol evoked a tonic vasoconstriction without producing tachyphylaxis. Bethanechol-induced phasic vasoconstriction was eliminated by perfusion with a Ca(2+)-free buffer. The L-type voltage-operated Ca(2+) channel blocker nifedipine decreased the maximal constrictor response to bethanechol by 59 +/- 2% (n = 4, P <.001), whereas the putative receptor-operated Ca(2+) channel blocker SK&F 96365 converted this vasoconstriction into vasodilation that was not mediated by nitric oxide. The protein kinase C inhibitor chelerythrine reduced the maximal phasic vasoconstrictor response to bethanechol by 78 +/- 2% (n = 6, P <.001) Bethanechol-induced tonic vasoconstriction was rapidly converted to a sustained vasodilation during infusion of SK&F 96365 or nifedipine, whereas infusion of chelerythrine gradually attenuated the tonic response to bethanechol. Results from other experiments do not support a role for phospholipase A(2)-dependent mediators in generating coronary vasoconstrictor responses to bethanechol. It is concluded that voltage-independent receptor-operated Ca(2+) channels, voltage-operated Ca(2+) channels, and protein kinase C are major signaling components for muscarinic receptor-mediated contraction of rat coronary resistance arteries.  (+info)

Parasympathetic non-adrenergic, non-cholinergic-induced protein synthesis and mitogenic activity in rat parotid glands. (8/144)

Electrical stimulation of the parasympathetic auriculo-temporal nerve (40 Hz, 30 min), in the anaesthetized rat under - and -adrenoceptor blockade, increased [3H]thymidine and [3H]leucine uptake into the parotid glands by 80 and 263 %, respectively. The increase in response to parasympathetic stimulation was almost the same ([3H]thymidine 82 % and [3H]leucine 283 %) when atropine (2 mg kg-1 I.P. or I.V.) was included in the pretreatment. Neither intravenous infusion of vasoactive intestinal peptide (0.5-20 mg kg-1 min-1, 30 min) nor of bethanechol (10 mg kg-1 min-1, 30 min), under adrenoceptor blockade, increased the uptake of [3H]thymidine into the glands. However, these drugs increased [3H]leucine uptake, and in combination they interacted positively. Whereas vasoactive intestinal peptide is likely to be involved in the parasympathetic nerve-evoked protein synthesis, the nature of the non-adrenergic, non-cholinergic component(s) involved in the mitogenic response is presently unknown.  (+info)

What is most likely to occur? After administering bethanechol to a - ProProfs DiscussWhat is most likely to occur? After administering bethanechol to a - ProProfs Discuss
The correct answer to this question is – Nausea and vomiting. Bethanechol is a cholinergic agonist drug that stimulates muscarinic receptors. It is mostly used to treat bladder problems such as urinary retention and inability to completely empty the bladder. Bethanechol works by increasing the tone of the detrusor muscle in the bladder. This causes a contraction in the bladder, and it is sufficient to cause urination and emptying of the bladder. Since bethanechol is a muscarinic receptor - ProProfs Discuss
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
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Bethanechol chloride / bethanechol chloride FDA New drug application 088288 international drug patent coverage, generic...Bethanechol chloride / bethanechol chloride FDA New drug application 088288 international drug patent coverage, generic...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
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Bethanechol - DrugBankBethanechol - DrugBank
Bethanechol is a synthetic ester structurally and pharmacologically related to acetylcholine. A slowly hydrolyzed muscarinic agonist with no nicotinic effects, bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, cardiac rate changes, and bronchial spasms.
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Bethanechol | ONSBethanechol | ONS
Bethanechol is a cholinergic agent that stimulates the parasympathetic nervous system. It is most often used related to its effect on improvement of bladder emptying and improvement in esophageal gastric sphincter pressure for reflux control. It is also a salivary stimulant. Bethanechol mouth rinse has been evaluated in patients with cancer in the prevention and management of mucositis. ...
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Bethanechol (Urecholine) 5mg Tablet, This is for priced for individual pills Bethanechol is prescribed to treat problems with urination due to nerve problems in the bladder, or weakness in certain bladder
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Has anyone tried bethanechol for their twitches? I noticed a thread on here from a few years ago were it totally got rid of the members twitches. I also have a friend that is a pharmacist that says that he has given it to customers for muscles spasms ...
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RX BETHANECHOL CHLORIDE 5MG,100 TAB, Other: shopmedvet.comRX BETHANECHOL CHLORIDE 5MG,100 TAB, Other: shopmedvet.com
To relieve pain that can be associated with disease, injury, or surgery a doctor may prescribe you a pharmaceutical to manage your pain. Pain medications are sorted into different types. Nonsteroidal anti-inflammatory drugs, Corticosteroids, Acetaminophen, Opioids, and Muscle relaxants.
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This medication is used to treat certain bladder problems such as the inability to urinate or empty the bladder completely due to certain causes (e.
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http://madeofgray.com/blog/one-day-early
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Why is this medication prescribed? Myotonachol (Bethanechol) is used to relieve urination difficulties caused by surgery, medications, or other factors.
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TY - JOUR. T1 - Effect of Cholinergic Agonists on Muscle From Rodent Proximal and Distal Small Intestine. AU - Nowak, Thomas V.. AU - Harrington, Bonnie. PY - 1985/1/1. Y1 - 1985/1/1. N2 - Proximal and distal rat small intestine was cut into strips measuring 6.0 × 10.0 mm. Strips cut along the oral-caudal axis were called longitudinal strips, whereas those cut 90° to that axis were called circular strips. Stress in circular and longitudinal muscle strips was measured continuously as they were superf used with acetylcholine, carbamylcholine, methacholine, bethanechol, or physostigmine. Resting stress during stretch, acetylcholine-stimulated active stress, and total stress were determined. Proximal circular muscle was five times as sensitive to acetylcholine as distal circular muscle (p , 0.05); proximal longitudinal muscle was 2.8 times as sensitive to bethanechol as distal muscle (p , 0.05). Resting, active, and total stress were similar in proximal and distal muscle, but circular muscle ...
https://indiana.pure.elsevier.com/en/publications/effect-of-cholinergic-agonists-on-muscle-from-rodent-proximal-and
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http://springerexemplar.com/search.aspx?q=mitomycin&P=5
Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone<...Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone<...
TY - JOUR. T1 - Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone. AU - Holmes, Gregory M.. AU - Browning, Kirsteen N.. AU - Babic, Tanja. AU - Fortna, Samuel R.. AU - Coleman, F. Holly. AU - Travagli, R. Alberto. PY - 2013/6/1. Y1 - 2013/6/1. N2 - Oxytocin (OXT) inputs to the dorsal vagal complex (DVC; nucleus of the tractus solitarius (NTS) dorsal motor nucleus of the vagus (DMV) and area postrema) decrease gastric tone and motility. Our first aim was to investigate the mechanism(s) of OXT-induced gastric relaxation. We demonstrated recently that vagal afferent inputs modulate NTS-DMV synapses involved in gastric and pancreatic reflexes via group II metabotropic glutamate receptors (mGluRs). Our second aim was to investigate whether group II mGluRs similarly influence the response of vagal motoneurons to OXT. Microinjection of OXT in the DVC decreased gastric tone in a dose-dependent manner. The OXT-induced gastric relaxation was enhanced following bethanechol and ...
https://pennstate.pure.elsevier.com/en/publications/vagal-afferent-fibres-determine-the-oxytocin-induced-modulation-o
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The relationship between muscarinic receptor-mediated inositol lipid hydrolysis and the generation of Ca2+ signals has been examined in human SK-N-SH neuroblastoma cells. The resting cytoplasmic calcium concentration [( Ca2+]i) as determined by fura-2 fluorescence measurements was 59 +/- 2 nM. Upon the addition of oxotremorine-M, there was a 4-fold increase in [Ca2+]i (293 +/- 18 nM), with half-maximal stimulation obtained at an agonist concentration of 8 microM, a value similar to that previously observed for the enhancement of phosphoinositide hydrolysis. Addition of partial muscarinic agonists for phosphoinositide turnover (bethanechol, oxo-2, and arecoline) elicited correspondingly smaller increases in [Ca2+]i than did oxotremorine-M. Inclusion of EGTA lowered the basal [Ca2+]i within 2 min and markedly reduced (greater than 60%) the magnitude of the agonist-induced rise in [Ca2+]i. Addition of muscarinic agonists to SK-N-SH cells that had been prelabeled with [3H]inositol led to the rapid ...
http://molpharm.aspetjournals.org/content/35/2/195
Ray Peat, PhD on Nitric OxideRay Peat, PhD on Nitric Oxide
Role of Serotonin in Preeclampsia. Prostaglandins, platelet activating factor, nitric oxide, peroxidase, lipases, histamine, serotonin, lactate, insulin, intracellular calcium, carbon dioxide, osmolarity, pH, and the redox environment are all relevant to cancer, and are affected systemically and locally by estrogen and progesterone in generally opposing ways.. And, obviously, drugs that are intended to increased the effects of nitric oxide (asparagine, zildenafil/Viagra, minoxidil/Rogaine) and acetylcholine (bethanechol, benzpyrinium, etc.) should be avoided.. The basic control of blood flow in the brain is the result of the relaxation of the wall of blood vessels in the presence of carbon dioxide, which is produced in proportion to the rate at which oxygen and glucose are being metabolically combined by active cells. In the inability of cells to produce CO2 at a normal rate, nitric oxide synthesis in blood vessels can cause them to dilate. The mechanism of relaxation by NO is very ...
http://www.functionalps.com/blog/2014/02/15/ray-peat-phd-on-nitric-oxide/
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Egon Bech Hansen - DTU FødevareinstituttetEgon Bech Hansen - DTU Fødevareinstituttet
Presented at: 8th International Symposium on Delivery of Funcionality in Complex Food Systems Type: Conference abstract for conference (Peer reviewed) Status: Published , År: 2019 ...
https://www.food.dtu.dk/forskning/tarmbakterier-og-sundhed/publikationer/person?id=68595&tab=2&qt=dtupublicationquery
Exploring the Mechanism of Agonist Efficacy: A Relationship between Efficacy and Agonist Dissociation Rate at the Muscarinic M3...Exploring the Mechanism of Agonist Efficacy: A Relationship between Efficacy and Agonist Dissociation Rate at the Muscarinic M3...
Chemicals and Reagents.l-[N-methyl]-[3H]Scopolamine methyl chloride ([3H]NMS; specific activity, 80-90 Ci/mmol) and guanosine 5′-O-(3-[35S]thio)triphosphate ([35S]GTPγS; specific activity, ,1000 Ci/mmol) and wheat germ agglutinin SPA beads were obtained from Amersham Biosciences (GE Healthcare, Chalfont St. Giles, Buckinghamshire, UK). The 96-deep-well plates and 500-cm2 cell culture plates were purchased from Thermo Fisher Scientific (Waltham, MA). The 96-well GF/B filter plates were purchased from Millipore (Watford, UK). HBSS, sodium bicarbonate, EDTA, sodium chloride, HEPES, dimethyl sulfoxide, BSA, GTP, GDP, saponin, probenecid, acetylcholine chloride, carbachol chloride, methacholine chloride, bethanechol chloride, oxotremorine-M, oxotremorine sesquifumarate, and pilocarpine hydrochloride were obtained from Sigma Chemical Co Ltd. (Poole, UK). Brilliant black was obtained from ICN Biomedicals Inc. (Solon, OH). Pluronic acid, Fluo-4-AM and all cell culture reagents were purchased from ...
http://molpharm.aspetjournals.org/content/76/3/543.full
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Modulation of Small-Intestinal Secretion and Absorption in Chronic Vitamin E Deficiency: Studies in Rat Jejunum in vitro |...Modulation of Small-Intestinal Secretion and Absorption in Chronic Vitamin E Deficiency: Studies in Rat Jejunum in vitro |...
1. A vicious cycle of malabsorption and malnutrition has been implicated in the pathogenesis of protracted diarrhoeal disease in infancy. Vitamin E deficiency is common in malnourished infants with protracted diarrhoea. We have studied the effects of chronic vitamin E deficiency on small-inestinal secretion and absorption in the rat.. 2. Weanling rats were fed vitamin E-sufficient or -deficient diets for 21 weeks. Jejunal function was studied in vitro in an Ussing chamber after this period.. 3. Steady-state isotopic flux experiments in unstimulated tissues demonstrated net Na+ and Cl−secretion in vitamin E-deficient jejuna but net Na+ and Cl− absorption in vitamin E-sufficient jejuna.. 4. Basal intestinal short-circuit current was the same in both groups.. 5. Cyclic nucleotide and maximal non-neuronal acetylcholine-mediated electrogenic secretion were increased in vitamin E-deficient jejuna.. 6. Exogenous 5-hydroxytryptamine (serotonin) induced a smaller increment in electrogenic secretion ...
http://www.clinsci.org/content/85/5/629
SciELO - Brazil - OCORRÊNCIA DE Gynandrobrotica caviceps adumbrata Bech. (COLEOPTERA: GALERUCINAE) NA CULTURA DA SOJA EM...SciELO - Brazil - OCORRÊNCIA DE Gynandrobrotica caviceps adumbrata Bech. (COLEOPTERA: GALERUCINAE) NA CULTURA DA SOJA EM...
NOTA OCORRÊNCIA DE Gynandrobrotica caviceps adumbrata Bech. (COLEOPTERA: GALERUCINAE) NA CULTURA DA SOJA EM PIRACICABA, SP J.B. PINHEIRO1; N.A. VELLO2 1Depto. de Agricultura-EA/UFG, C.P. 131, CEP: 74001-970 - Goiânia, GO. 2Depto. de Genética-ESALQ/USP, C.P. 83, CEP: 13400-970 - Piracicaba, SP. RESUMO: A presença de Gynadrobrotica caviceps adumbrata Bech. foi observada durante as safras de 1990/91 e 1991/92, infestando e danificando folhas de soja, em Piracicaba, SP. Este é o primeiro relato sobre este coleóptero danificando soja no Brasil. Descritores: inseto, praga, Glycine max, soja OCCURRENCE OF Gynandrobrotica caviceps adumbrata Bech. (COLEOPTERA: GALERUCINAE) IN SOYBEAN CROP IN PIRACICABA-SP, BRAZIL ABSTRACT: During the croping seasons of 1990/91 and 1991/92 the presence of Gynadrobrotica caviceps adumbrata Bech., was observed infesting and promoting damage on soybean leaves in Piracicaba, SP. This is the first report on this beetle damaging soybeans in Brazil. Key Words: insect, ...
https://www.scielo.br/j/sa/a/6j9ZYBJHzgFFD5sstPLmftG/?lang=pt
Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019 - Global Markets DirectsCalcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019 - Global Markets Directs
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Molecular and Cellular TherapiesMolecular and Cellular Therapies
Rikke Bech, Babak Jalilian, Ralf Agger, Lars Iversen, Mogens Erlandsen, Kristian Otkjaer, Claus Johansen, Søren R. Paludan, Carina A. Rosenberg, Knud Kragballe, Thomas Vorup-Jensen ...
http://molcelltherapies.com/index
Molecular and Cellular TherapiesMolecular and Cellular Therapies
Rikke Bech, Babak Jalilian, Ralf Agger, Lars Iversen, Mogens Erlandsen, Kristian Otkjaer, Claus Johansen, Søren R. Paludan, Carina A. Rosenberg, Knud Kragballe, Thomas Vorup-Jensen ...
http://molcelltherapies.com
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Nosch, Marie Louise Bech, 2014, KE-RA-ME-JA. Studies Presented to Cynthia W. Shelmerdine. Nakassis, D., Gulizio, J. & James, S. A. (red.). INSTAP Press, s. 91-101 11 s. (PREHISTORY MONOGRAPHS, Bind 46).. Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt ...
https://curis.ku.dk/portal/da/publications/search.html?publicationYearsFrom=2014&ordering=researchOutputOrderByPublicationYear&pageSize=10&publicationYearsTo=2014&page=1468&descending=true
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Pharmacological treatments directed at increasing cortical acetylcholine activity in patients with Alzheimers disease have largely been disappointing, perhaps because denervated areas of brain may not be exposed to adequate amounts of drug. A new method has been developed to enable localized intracerebral delivery of neurotransmitter substances using a polymeric drug delivery system. Microspheres of a polyanhydride sebacic acid copolymer were impregnated with bethanechol, an acetylcholinesterase-resistant cholinomimetic. Twenty rats received bilateral fimbria-fornix lesions, producing cholinergic denervation of the hippocampus and marked impairment in spatial memory. The animals were trained for 2 weeks to run an eight-arm radial maze, after which they received bilateral intrahippocampal implants of saline (five rats), blank polymer (five rats), or bethanechol-impregnated polymer (10 rats). Following implantation, spatial memory was assessed by radial-maze performance testing for 40 days. ...
https://thejns.org/search?authf=Grady%2C+M.+Sean&authf_0=Gross%2C+Alan&authf_1=Winn%2C+H.+Richard&f_0=author&pageSize=10&q_0=Marc+Mayberg&sort=date
About Us - Keith Yates DesignAbout Us - Keith Yates Design
ACOUSTICS AND PSYCHOACOUSTICS. Ando, Y. (1998). Architectural Acoustics: Blending Sound Sources, Sound Fields and Listeners. New York: Springer-Verlag. Attempting to fuse art and science, Ando combines subjective and objective factors involved in concert hall design with special attention to a model of the auditory-brain system.. Backus, J. (1969). The Acoustical Foundations of Music. New York: Norton.. Bech, S. (1998). Spatial Aspects of Reproduced Sound in Small Rooms. Journal of the Acoustical Society of America, 103 (1), 434-445. Part of a suite [see following] of important reports on the audibility of individual sound reflections off nearby walls in domestic-sized rooms.. Bech, S. (1995). Timbral Aspects of Reproduced Sound in Small Rooms, I. Journal of the Acoustical Society of America, 97 (3), 1717-1726.. Bech, S. (1996). Timbral Aspects of Reproduced Sound in Small Rooms, II. Journal of the Acoustical Society of America, 99 (6), 3539-3549.. Begault, D.R. (1994). 3-D Sound for Virtual ...
http://keithyates.com/about-us/
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Works In Progress - New Nordic FilmsWorks In Progress - New Nordic Films
In our intriguing Works in Progress section, we present new films currently in post-production. Selected scenes from each film, together with a short presentation, will give the participants an exclusive and unique preview of the upcoming lineup. The directors and/or producers will present their own films, each presentation lasting approximately 10 minutes.. This years Works in Progress takes place Thursday August 20th.. The line up for Works in Progress at the 2020 edition are:. Anatolian Leopard (Anadolu leopari) directed by Emre Kayis. Backyard Village (Þorpið í bakgarðinum) directed by Marteinn Thorsson. Band: This is Not a Band (Band: This is Not a Band) directed by Álfrún Örnólfsdóttir. Beautiful Land (Beautiful Land) directed by Torben Bech. A Blind Man Who Did Not Want to See Titanic (A Blind Man Who Did Not Want to See Titanic) directed by Teemu Nikki. Excess Will Save Us - The Movie (Excess Will Save Us - The Movie) directed by Morgane Dziurla-Petit). The Food Club ...
http://newnordicfilms.no/works-in-progress-2/
Find publikationer - Syddansk UniversitetFind publikationer - Syddansk Universitet
Bech, B., Primdahl, J., van Tubergen, A., Voshaar, M., Zangi, H. A., Barbosa, L., Boström, C., Boteva, B., Carubbi, F., Fayet, F., Ferreira, R. J. O., Hoeper, K., Kocher, A., Kukkurainen, M. L., Lion, V., Minnock, P., Moretti, A., Ndosi, M., Pavic Nikolic, M., Schirmer, M. & 4 flere, Smucrova, H., de la Torre-Aboki, J., Waite-Jones, J. & van Eijk-Hustings, Y., jan. 2020, I : Annals of the Rheumatic Diseases. 79, 1, s. 61-68. Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Formidling ...
https://portal.findresearcher.sdu.dk/da/publications/?id=112431543&format=&lastName=V&nofollow=true&name=T
Expectation of recovery from low back pain: a longitudinal cohort study investigating patient characteristics related to...Expectation of recovery from low back pain: a longitudinal cohort study investigating patient characteristics related to...
Spine (Phila Pa 1976). 2014 Jan 1;39(1):81-90. doi: 10.1097/BRS.0000000000000059. Kongsted A1, Vach W, Axø M, Bech RN, Hestbaek L. 1*Nordic Institute of Ch
https://medonline.at/2014/expectation-of-recovery-from-low-back-pain-a-longitudinal-cohort-study-investigating-patient-characteristics-related-to-expectations-and-the-association-between-expectations-and-3-month-outcome/
Posthuman Blues: That strange feeling is your head spinning.Posthuman Blues: That strange feeling is your head spinning.
The quest to observe the Higgs boson has certainly been plagued by its share of troubles, from the cancellation of the Superconducting Supercollider in 1993 to the Large Hadron Colliders streak of technical troubles. In fact, the projects have suffered such bad luck that Holger Bech Nielsen of the Niels Bohr Institute in Copenhagen and Masao Ninomiya of the Yukawa Institute for Theoretical Physics in Kyoto wonder if it isnt bad luck at all, but future influences rippling back to sabotage them. In papers like Test of Effect From Future in Large Hadron Collider: a Proposal and Search for Future Influence From LHC, they put forth the notion that observing the Higgs boson would be such an abhorrent event that the future is actually trying to prevent it from happening ...
http://posthumanblues.blogspot.com/2009/10/that-strange-feeling-is-your-head.html?showComment=1340094698533
Posthuman Blues: That strange feeling is your head spinning.Posthuman Blues: That strange feeling is your head spinning.
The quest to observe the Higgs boson has certainly been plagued by its share of troubles, from the cancellation of the Superconducting Supercollider in 1993 to the Large Hadron Colliders streak of technical troubles. In fact, the projects have suffered such bad luck that Holger Bech Nielsen of the Niels Bohr Institute in Copenhagen and Masao Ninomiya of the Yukawa Institute for Theoretical Physics in Kyoto wonder if it isnt bad luck at all, but future influences rippling back to sabotage them. In papers like Test of Effect From Future in Large Hadron Collider: a Proposal and Search for Future Influence From LHC, they put forth the notion that observing the Higgs boson would be such an abhorrent event that the future is actually trying to prevent it from happening ...
http://posthumanblues.blogspot.com/2009/10/that-strange-feeling-is-your-head.html?showComment=1262672734525
Autonomic drugAutonomic drug
Bethanechol is a muscarinic agonist. It is included in the therapy for underactive bladder with poor contraction of detrusor ... A low dose of Bethanechol is often used in treatment as increasing the dose can cause side effects like nausea, diarrhea and ... Since contraction of detrusor muscle in the bladder is controlled by the parasympathetic nervous system, Bethanechol can bind ...
https://en.wikipedia.org/wiki/Autonomic_drug
MargatoxinMargatoxin
Upon activation of muscarinic ACh receptors with bethanechol, margatoxin-sensitive current was suppressed. Therefore, it was ...
https://en.wikipedia.org/wiki/Margatoxin
DimethylphenylpiperaziniumDimethylphenylpiperazinium
Phenylpiperazine Prado WA, Segalla DK (August 2004). "Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in ...
https://en.wikipedia.org/wiki/Dimethylphenylpiperazinium
Alpha-3 beta-4 nicotinic receptorAlpha-3 beta-4 nicotinic receptor
Prado WA, Segalla DK (2004). "Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or ...
https://en.wikipedia.org/wiki/Alpha-3_beta-4_nicotinic_receptor
Anal fissureAnal fissure
Carapeti, E.; Kamm, M.; Phillips, R. (2000). "Topical Diltiazem and Bethanechol Decrease Anal Sphincter Pressure and Heal Anal ...
https://en.wikipedia.org/wiki/Anal_fissure
Neurogenic bladder dysfunctionNeurogenic bladder dysfunction
For urinary retention, cholinergics (muscarinic agonists) like bethanechol can improve the squeezing ability of the bladder. ...
https://en.wikipedia.org/wiki/Neurogenic_bladder_dysfunction
Betanehol - Википедија, слободна енциклопедијаBetanehol - Википедија, слободна енциклопедија
Carter WJ (2008). „Unexpected benefits of bethanechol in adults with cerebral palsy". Med. J. Aust. 189 (5): 293. PMID 18759732 ...
https://sr.wikipedia.org/wiki/Betanehol
Equine proximal enteritisEquine proximal enteritis
Prokinetic drugs such as lidocaine, erythromycin, metoclopramide, and bethanechol are often used to treat the ileus associated ...
https://en.wikipedia.org/wiki/Equine_proximal_enteritis
PilocarpinePilocarpine
Bethanechol-a similar muscarinic parasympathomimetic with longer lasting effect "Pilocarpine". The American Society of Health- ...
https://en.wikipedia.org/wiki/Pilocarpine
Underactive bladderUnderactive bladder
Treatment frequently includes lifestyle modification (fluid restriction, bladder retraining). Bethanechol is a prescription ... medication used for treatment, bethanechol can stimulate the nerves of the bladder, making them more responsive to stimulus. ...
https://en.wikipedia.org/wiki/Underactive_bladder
Overflow incontinenceOverflow incontinence
Medications Bethanechol (Management of overflow incontinence by activating muscarinic receptors in the bladder and stimulating ...
https://en.wikipedia.org/wiki/Overflow_incontinence
MethoctramineMethoctramine
... such as bethanechol or berberine). At higher concentrations, allosteric properties of methoctramine have also been described. ...
https://en.wikipedia.org/wiki/Methoctramine
Said AwadSaid Awad
"The effectiveness of bethanechol chloride in lower motor neuron lesions: The importance of mode of administration" Neurourology ... "The dependence of sustained bladder contractions provoked by filling or by subcutaneous bethanechol upon sacral afferent ...
https://en.wikipedia.org/wiki/Said_Awad
CevimelineCevimeline
Bethanechol - a similar muscarinic parasympathomimetic with longer-lasting effect Ono M, Takamura E, Shinozaki K, et al. (July ...
https://en.wikipedia.org/wiki/Cevimeline
MegacolonMegacolon
Bethanechol can also be used to treat megacolon by means of its direct cholinergic action and its stimulation of muscarinic ...
https://en.wikipedia.org/wiki/Megacolon
Trimethyl ammonium compoundsTrimethyl ammonium compounds
Examples include: Betaine Bethanechol Carnitine and its derivatives Choline and its derivatives Methacholine Muscarine ...
https://en.wikipedia.org/wiki/Trimethyl_ammonium_compounds
Parasympathomimetic drugParasympathomimetic drug
Choline esters Acetylcholine (all acetylcholine receptors) Bethanechol (M3 receptors) Carbachol (all muscarinic receptors and ...
https://en.wikipedia.org/wiki/Parasympathomimetic_drug
List of veterinary drugsList of veterinary drugs
... chronic kidney failure and protein-losing nephropathy bethanechol - stimulates bladder contractions, tranquilizer, makes the ...
https://en.wikipedia.org/wiki/List_of_veterinary_drugs
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M3
acetylcholine bethanechol carbachol L-689,660 (mixed M1/M3 agonist) oxotremorine pilocarpine (in eye) atropine hyoscyamine ...
https://en.wikipedia.org/wiki/Muscarinic_acetylcholine_receptor_M3
Peripherally selective drugPeripherally selective drug
L-amino acid decarboxylase inhibitor used in combination with levodopa in the treatment of Parkinson's disease Bethanechol - a ...
https://en.wikipedia.org/wiki/Peripherally_selective_drug
List of drugs: BeList of drugs: Be
Bethanechol (INN) Betiatide (INN) Betimol Betnesol Betnovate Betoptic Pilo Betoptic S Betoxycaine (INN) Betrixaban (USAN) ...
https://en.wikipedia.org/wiki/List_of_drugs:_Be
ATC code N07ATC code N07
... combinations N07AB01 Carbachol N07AB02 Bethanechol N07AX01 Pilocarpine N07AX02 Choline alfoscerate N07AX03 Cevimeline N07BA01 ...
https://en.wikipedia.org/wiki/ATC_code_N07
BethanecholBethanechol
The name bethanechol refers to its structure as the urethane of beta-methylcholine. Bethanechol alleviates dry mouth and is ... Bethanechol should be used to treat these disorders only after mechanical obstruction is ruled out as a possible cause. Its ... Use of bethanechol, as well as all other muscarinic receptor agonists, is contraindicated in patients with asthma, coronary ... Unlike acetylcholine, bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action. ...
https://en.wikipedia.org/wiki/Bethanechol
ಖಿನ್ನತೆ-ಶಮನಕಾರಿ(ಆಂಟಿ-ಡಿಪ್ರೆಸೆಂಟ್) - ವಿಕಿಪೀಡಿಯಖಿನ್ನತೆ-ಶಮನಕಾರಿ(ಆಂಟಿ-ಡಿಪ್ರೆಸೆಂಟ್) - ವಿಕಿಪೀಡಿಯ
"Reversal by bethanechol of sexual dysfunction caused by anticholinergic antidepressants". The American Journal of Psychiatry ...
https://kn.wikipedia.org/wiki/ಖಿನ್ನತೆ-ಶಮನಕಾರಿ
Dawa za mfadhaiko, kamusi elezo huruDawa za mfadhaiko, kamusi elezo huru
"Reversal by bethanechol of sexual dysfunction caused by anticholinergic antidepressants". The American Journal of Psychiatry ...
https://sw.wikipedia.org/wiki/Dawa_za_mfadhaiko
Antidepressant, ang malayang ensiklopedyaAntidepressant, ang malayang ensiklopedya
Ang Bethanechol ay iniulat na bumabaliktad ng pinukaw ng MAOI na hindi pagganang sekswal sa pamamagitan ng katangiang agonista( ...
https://tl.wikipedia.org/wiki/Antidepresant
FesoterodineFesoterodine
InChI=1S/C26H37NO3/c1-18(2)26(29)30-25-13-12-21(17-28)16-24(25)23(22-10-8-7-9-11-22)14-15-27(19(3)4)20(5)6/h7-13,16,18-20,23,28H,14-15,17H2,1-6H3/t23-/m1/s1 ...
https://en.wikipedia.org/wiki/Fesoterodine
MethanthelineMethantheline
The topic of this article may not meet Wikipedia's general notability guideline. Please help to establish notability by citing reliable secondary sources that are independent of the topic and provide significant coverage of it beyond a mere trivial mention. If notability cannot be established, the article is likely to be merged, redirected, or deleted ...
https://en.wikipedia.org/wiki/Methantheline
CaptodiameCaptodiame
... (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. The structure is related to diphenhydramine.[1] A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.[1] In addition to its actions as an antihistamine, captodiamine has been found to act as a 5-HT2C receptor antagonist and σ1 receptor and D3 receptor agonist.[2] It produces antidepressant-like effects in rats.[2] However, captodiamine is unique among antidepressant-like drugs in that it increases brain-derived neurotrophic factor (BDNF) levels in the hypothalamus but not in the frontal cortex or hippocampus.[2] This unique action may be related to its ability to attenuate stress-induced anhedonia and corticotropin-releasing factor (CRF) signaling in the hypothalamus.[2] ...
https://en.wikipedia.org/wiki/Captodiame
Clidinium bromideClidinium bromide
Used in fixed combination with chlordiazepoxide as adjunctive therapy in the treatment of peptic ulcer disease; however, no conclusive data that antimuscarinics aid in the healing, decrease the rate of recurrence, or prevent complications of peptic ulcers.[2] With the advent of more effective therapies for the treatment of peptic ulcer disease, antimuscarinics have only limited usefulness in this condition. ...
https://en.wikipedia.org/wiki/Clidinium_bromide
Bethanechol: MedlinePlus Drug InformationBethanechol: MedlinePlus Drug Information
Bethanechol: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Bethanechol comes as a tablet to take by mouth. Bethanechol usually is taken two to four times a day. Follow the directions on ... Before taking bethanechol,. *tell your doctor and pharmacist if you are allergic to bethanechol or any other drugs. ... Take bethanechol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. ...
https://medlineplus.gov/druginfo/meds/a682849.html
Bethanechol - WikipediaBethanechol - Wikipedia
The name bethanechol refers to its structure as the urethane of beta-methylcholine. Bethanechol alleviates dry mouth and is ... Bethanechol should be used to treat these disorders only after mechanical obstruction is ruled out as a possible cause. Its ... Use of bethanechol, as well as all other muscarinic receptor agonists, is contraindicated in patients with asthma, coronary ... Unlike acetylcholine, bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action. ...
https://en.wikipedia.org/wiki/Bethanechol
Bethanechol - Drugs and Lactation Database (LactMed) - NCBI BookshelfBethanechol - Drugs and Lactation Database (LactMed) - NCBI Bookshelf
No information is available on the use of bethanechol during breastfeeding. If it is used during breastfeeding, monitor the ... Bethanechol - Drugs and Lactation Database (LactMed). Bethanechol - Drugs and Lactation Database (LactMed). ... No information is available on the use of bethanechol during breastfeeding. If it is used during breastfeeding, monitor the ... Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Bethanechol. [ ...
https://www.ncbi.nlm.nih.gov/books/NBK501656/
Bethanechol - definition of bethanechol by The Free DictionaryBethanechol - definition of bethanechol by The Free Dictionary
bethanechol synonyms, bethanechol pronunciation, bethanechol translation, English dictionary definition of bethanechol. n. A ... bethanechol. Also found in: Medical, Wikipedia.. Related to bethanechol: Bethanechol chloride. be·than·e·chol. (bĕ-thăn′ĭ-kôl ... Bethanechol - definition of bethanechol by The Free Dictionary https://www.thefreedictionary.com/bethanechol ... Bethanechol is a cholinergic agent used to treat urinary retention related to bladder atony.. Getting Ready for Certification: ...
https://www.thefreedictionary.com/bethanechol
DailyMed - BETHANECHOL CHLORIDE tabletDailyMed - BETHANECHOL CHLORIDE tablet
BETHANECHOL CHLORIDE tablet. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader application. ... Bethanechol Chloride Tablets, USP 5 mg tablets are white, 7/16" diameter, round flat faced bevel edge tablets; one side scored ... BETHANECHOL CHLORIDE tablet. If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be ... Bethanechol chloride tablets should preferably be taken one hour before or two hours after meals to avoid nausea or vomiting. ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=80393410-dd51-4cac-b27c-50ece00cca37
DailyMed - BETHANECHOL CHLORIDE tabletDailyMed - BETHANECHOL CHLORIDE tablet
BETHANECHOL CHLORIDE tablet. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader application. ... BETHANECHOL CHLORIDE tablet. If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be ... Bethanechol chloride tablets should preferably be taken one hour before or two hours after meals to avoid nausea or vomiting. ... Bethanechol chloride does not cross the blood-brain barrier because of its charged quaternary amine moiety. The metabolic rate ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6a0a2d15-e67c-41d9-85fd-bafe9b3fb7e2
bethanechol | Cignabethanechol | Cigna
Bethanechol is used to treat urinary retention (difficulty urinating), which may occur after surgery, after delivering a baby, ... Bethanechol may also be used for purposes other than those listed in this medication guide. ... What is bethanechol?. Bethanechol stimulates your bladder to empty.. Bethanechol is used to treat urinary retention (difficulty ... Bethanechol is in the FDA pregnancy category C. This means that it is not known whether bethanechol will harm an unborn baby. ...
https://www.cigna.com/individuals-families/health-wellness/hw/medications/bethanechol-d01427a1
Bethanechol: uses & side-effects | PatientsLikeMeBethanechol: uses & side-effects | PatientsLikeMe
Find the most comprehensive real-world treatment information on Bethanechol at PatientsLikeMe. 26 patients with fibromyalgia, ... bipolar I disorder or psoriasis currently take Bethanechol. ... 2 patient evaluations for Bethanechol Sort by: Most recent * ...
https://www.patientslikeme.com/treatment/3339-duvoid-side-effects-and-efficacy
Bethanechol Oral, Subcutaneous Advanced Patient Information - Drugs.comBethanechol Oral, Subcutaneous Advanced Patient Information - Drugs.com
Detailed drug Information for bethanechol Oral, Subcutaneous. Includes common brand names, drug descriptions, warnings, side ... Overactive thyroid-Bethanechol may further increase the chance of heart problems. Proper Use of bethanechol. Take bethanechol ... Uses For bethanechol. Bethanechol is taken to treat certain disorders of the urinary tract or bladder. It helps to cause ... Bethanechol is available only with your doctors prescription.. Before Using bethanechol. In deciding to use a medicine, the ...
https://www.drugs.com/cons/bethanechol-oral-subcutaneous.html
Bethanechol - DrugBankBethanechol - DrugBank
A slowly hydrolyzed muscarinic agonist with no nicotinic effects, bethanechol is generally used to increase smooth muscle tone ... Bethanechol is a synthetic ester structurally and pharmacologically related to acetylcholine. ... Bethanechol. Accession Number. DB01019 (APRD00051) Type. Small Molecule. Groups. Approved. Description. Bethanechol is a ... Bethanechol Chloride. Tablet. 25 mg/1. Oral. Lake Erie Medical DBAQuality Care Products LLC. 2015-08-06. 2016-06-01. US. ...
https://www.drugbank.ca/drugs/DB01019
Bethanechol - UniprixBethanechol - Uniprix
BETHANECHOL, 50MG, TABLET. Common uses. This medication is typically used for urinary retention (difficulty passing urine). It ...
https://www.uniprix.com/en/drug-lexicon/02237049/Bethanechol
Bethanechol chloride 10mg tablets | LloydsPharmacyBethanechol chloride 10mg tablets | LloydsPharmacy
Great price on Bethanechol chloride 10mg tablets. FREE delivery options available. Trusted service, convenient and safe ... Bethanechol chloride 10mg tablets. Registered UK Online Pharmacy - Prescription item. To purchase this item you must have a ...
http://www.lloydspharmacy.com/en/bethanechol-chloride-10mg-tablets
What is the half life time for bethanechol ? and metabolism?What is the half life time for bethanechol ? and metabolism?
... bethanechol - Answer: The half life and route of metabolism for bethanechol are ... ... Side Effects of Bethanechol (detailed). Search for questions. Still looking for answers? Try searching for what you seek or ask ... What is the half life time for bethanechol ? and metabolism?. Asked. 18 Apr 2011 by yassmoon. Updated. 19 April 2011. Topics. ... Does bethanechol chloride have any curative effect? Is there any danger in taking it long-term?. Posted 21 Jan 2010 • 1 answer ...
https://www.drugs.com/answers/what-is-the-half-life-time-for-bethanechol-and-394304.html
Bethanechol | ONSBethanechol | ONS
Bethanechol is a cholinergic agent that stimulates the parasympathetic nervous system. It is most often used related to its ... Bethanechol did not appear to reduce the incidence of mucositis, candidiasis, or taste loss when administered during RT. ... Bethanechol mouth rinse has been evaluated in patients with cancer in the prevention and management of mucositis. ... Jham, B.C., Chen, H., Carvalho, A.L., & Freire, A.R. (2009). A randomized phase III prospective trial of bethanechol to prevent ...
https://www.ons.org/intervention/bethanechol
PMS-bethanechol - Uses, Side Effects, Interactions - MedBroadcast.comPMS-bethanechol - Uses, Side Effects, Interactions - MedBroadcast.com
Bethanechol chloride is also used by people who have trouble urinating after surgery or after delivering a baby. ... PMS-bethanechol: This medication is used to treat problems with urination due to nerve problems in the bladder or weakness in ... 00739162 PMS-BETHANECHOL CHLORIDE TAB 25MG. 00759171 PMS-BETHANECHOL CHLORIDE TAB 10MG. 00759198 PMS-BETHANECHOL CHLORIDE TAB ... Bethanechol chloride should not be taken by anyone who:. *is allergic to bethanechol chloride or to any of the ingredients of ...
https://medbroadcast.com/drug/getdrug/pms-bethanechol
Bethanechol 25 mg, 100 Tablets | VetDepot.comBethanechol 25 mg, 100 Tablets | VetDepot.com
... then your veterinarian may prescribe Bethanechol 25 mg, 100 Tablets. Save money by ordering it from VetDepot. ... If your dog has problems emptying their bladder, then your veterinarian may prescribe Bethanechol 25 mg, 100 Tablets. This ... ", "prodUrl":"/bethanechol-50-mg-100-tablets.html", "vars": [ {"varInfo":["mg","50"]} ] }, { "prodNum":"1041088", "prodUrl":"/ ... bethanechol-5-mg-100-tablets.html", "vars": [ {"varInfo":["mg","5"]} ] }, { "prodNum":"1041087", "prodUrl":"/bethanechol-25-mg- ...
https://www.vetdepot.com/bethanechol-25-mg-100-tablets.html
Bethanechol 50 mg, 100 Tablets | VetDepot.comBethanechol 50 mg, 100 Tablets | VetDepot.com
Choose Bethanechol 50 mg, 100 Tablets to treat urinary problems in dogs caused by nerve damage or weak bladder muscles. Save ... Bethanechol 50 mg, 100 Tablets is a prescription medication used to increase the strength of bladder contractions. It helps ... ", "prodUrl":"/bethanechol-50-mg-100-tablets.html", "vars": [ {"varInfo":["mg","50"]} ] }, { "prodNum":"1041088", "prodUrl":"/ ... bethanechol-5-mg-100-tablets.html", "vars": [ {"varInfo":["mg","5"]} ] }, { "prodNum":"1041087", "prodUrl":"/bethanechol-25-mg- ...
https://www.vetdepot.com/bethanechol-50-mg-100-tablets.html
Bethanechol chloride USP * (CAS 590-63-6) Market Research Report 2018Bethanechol chloride USP * (CAS 590-63-6) Market Research Report 2018
The report generally describes bethanechol chloride usp *, examines its uses, production methods, patents. Bethanechol chloride ... Bethanechol chloride usp * prices in other regions. 7. BETHANECHOL CHLORIDE USP * END-USE SECTOR 7.1. Bethanechol chloride usp ... Bethanechol chloride usp * market forecast. 6. BETHANECHOL CHLORIDE USP * MARKET PRICES. 6.1. Bethanechol chloride usp * prices ... 3. BETHANECHOL CHLORIDE USP * MANUFACTURING METHODS. 4. BETHANECHOL CHLORIDE USP * PATENTS. Abstract. Description. Summary of ...
https://marketpublishers.com/report/industry/chemicals_petrochemicals/bethanechol_chloride_usp_590-63-6_market_research_report.html
Drug - Urivoid (25mg) - 10 Tablet (Bethanechol - Combination of Generics ) Price List or Cost of Medication | MedindiaDrug - Urivoid (25mg) - 10 Tablet (Bethanechol - Combination of Generics ) Price List or Cost of Medication | Medindia
Bethanechol - Combination of Generics) drug information. Find its price or cost, dose, when to use, how to use, side effects, ... When is Bethanechol not to be taken? (Contraindications). Bethanechol is contraindicated in patients who are allergic to the ... Bethanechol is a powerful cholinergic agent. It stimulates the bladder muscle to improve the urine flow and thereby helps in ... Bethanechol is sometimes prescribed by the doctor for abdominal distension due to dilated colon and in the treatment of ...
https://www.medindia.net/drug-price/bethanechol-combination/urivoid-25mg.htm
bethanechol chloride (Urecholine) Price Comparisons - Discounts, Cost & Coupons - U.S. | PharmacyChecker.combethanechol chloride (Urecholine) Price Comparisons - Discounts, Cost & Coupons - U.S. | PharmacyChecker.com
Print free coupons for bethanechol chloride and find the best deal on your prescription medications today. ... Compare bethanechol chloride (Urecholine) 5 MG prices at pharmacies near me. ... Bethanechol chloride (Urecholine) Prices The lowest price for Bethanechol chloride (Urecholine) 5 MG is found at local U.S. ... The lowest price for Bethanechol chloride (Urecholine) 5 MG is found at local U.S. pharmacies. PharmacyChecker-accredited ...
https://www.pharmacychecker.com/bethanechol+chloride/
Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects | GutTopical diltiazem and bethanechol decrease anal sphincter pressure without side effects | Gut
In the second and third studies diltiazem and bethanechol gels of increasing concentration were applied topically to lower anal ... CONCLUSIONS Topical diltiazem and bethanechol substantially reduce anal sphincter pressure for a prolonged period, and ... Diltiazem and bethanechol gel produced a dose dependent reduction of the anal pressure; 2% diltiazem produced a maximal 28% ... reduction, and 0.1% bethanechol a maximal 24% reduction, the effect lasting three to five hours. ...
http://gut.bmj.com/content/45/5/719.full
What is most likely to occur? After administering bethanechol to a - ProProfs DiscussWhat is most likely to occur? After administering bethanechol to a - ProProfs Discuss
Bethanechol works by increasing the tone of the detrusor muscle in the bladder. This causes a contraction in the bladder, and ... Bethanechol is a cholinergic agonist drug that stimulates muscarinic receptors. It is mostly used to treat bladder problems ... Since bethanechol is a muscarinic receptor - ProProfs Discuss ... In high doses, bethanechol can also cause a decrease in cardiac ... Bethanechol is a cholinergic agonist drug that stimulates muscarinic receptors. It is mostly used to treat bladder problems ...
https://www.proprofs.com/discuss/q/1495565/after-administering-bethanechol-patient-urine-retention-nurs?utm_source=quiz_topic_page&utm_medium=discuss_button_click&utm_campaign=quiz_topic_page_discuss_button_click
Urecholine (bethanechol chloride) dose, indications, adverse effects, interactions... from PDR.netUrecholine (bethanechol chloride) dose, indications, adverse effects, interactions... from PDR.net
Bethanechol also stimulates the lower GI tract, producing defecation. Bethanechol produces a much more vigorous response in ... Bethanechol is contraindicated in patients with asthma; Bethanechol should also be avoided in chronic obstructive pulmonary ... Bethanechol also stimulates ureteral peristalsis and relaxes the trigone and external sphincter. Because bethanechol is a ... Bethanechol is administered orally and subcutaneously. After administration, the distribution of bethanechol is not well known ...
http://www.pdr.net/drug-summary/Urecholine-bethanechol-chloride-801
bethanechol | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGYbethanechol | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
bethanechol ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ... Bethanechol is structurally and pharmacologically related to acetylcholine.. Marketed formulations may contain bethanechol ...
http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=297
Urecholine (bethanechol) dosing, indications, interactions, adverse effects, and moreUrecholine (bethanechol) dosing, indications, interactions, adverse effects, and more
... bethanechol), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, ... encoded search term (bethanechol (Urecholine)) and bethanechol (Urecholine) What to Read Next on Medscape. Medscape Consult. ... Since bethanechol contracts the bladder there is potential for influx infection if the sphincter fails to relax ... Because of the potential for serious adverse reactions from bethanechol chloride in nursing infants, a decision should be made ...
https://reference.medscape.com/drug/urecholine-bethanechol-343056
Bethanechol - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWikiBethanechol - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
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UrecholineBladderTabletDuvoid25MGTabletsName bethanecholCholinergic agentUrinary retentionPilocarpineUnusual or allergic reaction to bethanecholAgonistAnal sphincter pressureMedicationDrugsContraindicationsAdministration of bethanechol2018Take bethanecholAustralia bethanecholDosesPharmacologyParasympathetic nervouPrescriptionOralMotilityNicotinicDetrusorSalivationSide effectsUrineStimulationSurgerySyntheticHydrolyzed by cholinesteraseDosePrecautionsMuscarinic receptorCross the blood-brain bNauseaDiltiazemCause dizzinessInabilityParasympathomimeticHttpsObstructionGenericPillMedicines
Urecholine9
  • Bethanechol is sold under the brand names Duvoid (Roberts), Myotonachol (Glenwood), Urecholine (Merck Frosst) and Urocarb (Hamilton). (wikipedia.org)
  • The cholinergics oral bethanechol (such as Urecholine) [C] and injectable neostigmine (Prostigmin) [C] are used for urinary retention, and bethanechol is used for postpartum nonobstructive urinary retention. (thefreedictionary.com)
  • The lowest price for Bethanechol chloride (Urecholine) 5 MG is found at local U.S. pharmacies. (pharmacychecker.com)
  • Urecholine (bethanechol) is a small molecule pharmaceutical. (biometadata.com)
  • Bethanechol was first approved as Urecholine on 1982-01-01. (biometadata.com)
  • bethanechol prices south africa buy can i buy urecholine at a local drug store buy bethanechol 25 mg identification so here is some information to help. (aircus.com)
  • What is the most important information I should know about Urecholine (bethanechol)? (worthmeds.com)
  • What should I discuss with my healthcare provider before taking Urecholine (bethanechol)? (worthmeds.com)
  • What should I avoid while taking Urecholine (bethanechol)? (worthmeds.com)
Bladder20
  • Atropine is given preoperatively to prevent voiding of the bowel/bladder during surgery, Bethanechol is then given postoperatively to revert this action. (wikipedia.org)
  • Bethanechol is a cholinergic agent used to treat urinary retention related to bladder atony. (thefreedictionary.com)
  • 23-24, July 1977) was conducted on the relative effectiveness of oral and subcutaneous doses of bethanechol chloride on the stretch response of bladder muscle in patients with urinary retention. (nih.gov)
  • Bethanechol chloride is indicated for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. (nih.gov)
  • Bethanechol stimulates your bladder to empty. (cigna.com)
  • Bethanechol is taken to treat certain disorders of the urinary tract or bladder. (drugs.com)
  • If your dog has problems emptying their bladder, then your veterinarian may prescribe Bethanechol 25 mg, 100 Tablets. (vetdepot.com)
  • Bethanechol 50 mg, 100 Tablets is a prescription medication used to increase the strength of bladder contractions. (vetdepot.com)
  • Bethanechol works by increasing the tone of the detrusor muscle in the bladder. (proprofs.com)
  • Bethanechol use is contraindicated when the strength or integrity of the gastrointestinal or bladder wall is questionable. (pdr.net)
  • Bethanechol belongs to a group of drugs called cholinergic agents, which help muscles work to empty urine from the bladder. (rxwiki.com)
  • Uses/Indications - In veterinary medicine, bethanechol is used primarily to stimulate bladder contractions in small animals. (elephantcare.org)
  • BETHANECHOL (be THAN e kole) stimulates the bladder. (yourcareeverywhere.com)
  • Bethanechol stimulates the detrusor muscle of the bladder, promoting mictruition. (pathwaymedicine.org)
  • Consequently, bethanechol has been used to treat atonic bladder, potentially as a result of neurogenic bladder. (pathwaymedicine.org)
  • Bethanechol is prescribed to treat problems with urination due to nerve problems in the bladder, or weakness in certain bladder muscles. (californiapetpharmacy.com)
  • Bethanechol is useful in treating bladder atony which occur in post operative period or post partum. (medicalzone.net)
  • Bethanechol will stimulates the M3 receptors which cause an increase in contraction of the bladder with relaxation of the sphincter of the bladder. (medicalzone.net)
  • In urinary retention, if the sphincter fails to relax as bethanechol contracts the bladder, urine may be forced up the ureter into the kidney pelvis. (medlibrary.org)
  • Since contraction of detrusor muscle in the bladder is controlled by the parasympathetic nervous system, Bethanechol can bind to muscarinic receptors to stimulate activation of the parasympathetic nervous system and restore contraction of detrusor muscle. (wikipedia.org)
Tablet4
  • Bethanechol comes as a tablet to take by mouth. (medlineplus.gov)
  • Each tablet for oral administration contains 5 mg, 10 mg, 25 mg or 50 mg bethanechol chloride, USP. (nih.gov)
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Duvoid1
  • Prokinetic agents include metoclopramide (also known as Reglan), bethanechol (Duvoid) and tegaserod (Zelnorm). (thefreedictionary.com)
25MG1
Tablets2
  • Storage/Stability/Compatibility - Bethanechol tablets should be stored at room temperature in tight containers. (elephantcare.org)
  • To ascertain how elevation of the head of the bed, bethanechol, and antacid foam tablets affect gastroesophageal reflux, we used prolonged intraesophageal pH monitoring in 55 symptomatic patients. (gerdhelp.com)
Name bethanechol1
  • The name bethanechol refers to its structure as the urethane of beta-methylcholine. (wikipedia.org)
Cholinergic agent3
  • Bethanechol chloride, USP, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine. (nih.gov)
  • Bethanechol is a cholinergic agent that stimulates the parasympathetic nervous system. (ons.org)
  • Bethanechol is a powerful cholinergic agent. (medindia.net)
Urinary retention4
  • Consider a trial of a cholinergic agonist, such as bethanechol , in patients with urinary retention. (thefreedictionary.com)
  • Bethanechol is used to treat urinary retention (difficulty urinating), which may occur after surgery, after delivering a baby, and in other situations. (cigna.com)
  • A slowly hydrolyzed muscarinic agonist with no nicotinic effects, bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. (drugbank.ca)
  • Bethanechol is used to treat urinary retention (difficulty passing urine) caused by surgery, drugs or other factors. (singhealth.com.sg)
Pilocarpine1
  • 15. The method of claim 14, wherein the muscarinic agonist is selected from the group consisting of pilocarpine, isopilocarpine lactam, carbachol, bethanechol, methacholine and muscarine. (freepatentsonline.com)
Unusual or allergic reaction to bethanechol1
  • Tell your doctor if you have ever had any unusual or allergic reaction to bethanechol or any other medicines. (drugs.com)
Agonist6
  • The second approach is to attempt to correct the lysosomal defect by a cholinergic agonist, bethanechol chloride. (thefreedictionary.com)
  • Bethanechol is a cholinergic agonist drug that stimulates muscarinic receptors. (proprofs.com)
  • Bethanechol Chloride is an agonist selective for Muscarinic Acetylcholine Receptors with no effect on nicotinic receptors. (emdmillipore.com)
  • Bethanechol is a synthetic direct-acting cholinergic agonist with a specificity for muscarinic receptors . (pathwaymedicine.org)
  • Bethanechol Chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors. (ebiochemicals.com)
  • Bethanechol is a muscarinic agonist. (wikipedia.org)
Anal sphincter pressure3
  • Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects. (thefreedictionary.com)
  • Topical diltiazem and bethanechol decrease anal sphincter pressure and heal anal fissures without side effects. (thefreedictionary.com)
  • CONCLUSIONS Topical diltiazem and bethanechol substantially reduce anal sphincter pressure for a prolonged period, and represent potential low side effect alternatives to topical nitrates for the treatment of anal fissures. (bmj.com)
Medication2
  • Bethanechol may also be used for purposes other than those listed in this medication guide. (cigna.com)
  • Is bethanechol over the counter medication? (discoverhoustontours.com)
Drugs4
  • Bethanechol is used to relieve difficulties in urinating caused by surgery, drugs, or other factors. (medlineplus.gov)
  • tell your doctor and pharmacist if you are allergic to bethanechol or any other drugs. (medlineplus.gov)
  • Using bethanechol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. (drugs.com)
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Contraindications1
  • BETHANECHOL CHLORIDE - RobHolland In Bethanechol - Uses, Reviews, Side-effects, and Contraindications the growing practice. (daralrahmah.co.uk)
Administration of bethanechol2
  • Effects on the GI and urinary tracts sometimes appear within 30 minutes after oral administration of bethanechol chloride, but more often 60 to 90 minutes are required to reach maximum effectiveness. (nih.gov)
  • After subcutaneous administration of bethanechol, the patient should be observed for 30 minutes to 1 hour for possible severe reactions, and a syringe containing a dose of atropine should be immediately available to promptly counteract adverse effects. (pdr.net)
20182
  • Bethanechol chloride USP * (CAS 590-63-6) Market Research Report 2018 contents were worked out and placed on the website in March, 2018. (marketpublishers.com)
  • Please note that Bethanechol chloride USP * (CAS 590-63-6) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
Take bethanechol6
  • Take bethanechol exactly as directed. (medlineplus.gov)
  • Take bethanechol on an empty stomach 1 hour before or 2 hours after meals to prevent nausea and vomiting. (cigna.com)
  • You may not be able to take bethanechol, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. (cigna.com)
  • How should I take bethanechol? (cigna.com)
  • Take bethanechol on an empty stomach (either 1 hour before or 2 hours after meals) to lessen the possibility of nausea and vomiting, unless otherwise directed by your doctor. (drugs.com)
  • What food or medicine must I avoid when I take Bethanechol? (singhealth.com.sg)
Australia bethanechol1
  • Function texas can reduce australia bethanechol for sale, while diseases are prescribed for obliteration. (discoverhoustontours.com)
Doses5
  • Following oral administration, the usual duration of action of bethanechol chloride is one hour, although large doses (300 to 400 mg) have been reported to produce effects for up to six hours. (nih.gov)
  • Because of the selective action of bethanechol chloride, nicotinic symptoms of cholinergic stimulation are usually absent or minimal when orally or subcutaneously administered in therapeutic doses, while muscarinic effects are prominent. (nih.gov)
  • The following information includes only the average doses of bethanechol. (drugs.com)
  • In high doses, bethanechol can also cause a decrease in cardiac contractions. (proprofs.com)
  • With high doses of bethanechol, cardiovascular responses may include vasodilation, decreased cardiac rate, and decreased force of cardiac contraction, which may cause hypotension. (proprofs.com)
Pharmacology1
  • Pharmacology - Bethanechol directly stimulates cholinergic receptors. (elephantcare.org)
Parasympathetic nervou1
  • Bethanechol chloride acts principally by producing the effects of stimulation of the parasympathetic nervous system. (nih.gov)
Prescription2
  • Bethanechol is available only with your doctor's prescription. (drugs.com)
  • As the disease advances children may experience mental impairment, buy bethanechol online uk no prescription The doctor tells you that you are going to have to start self monitoring your blood sugar levels at home. (aircus.com)
Oral2
  • In humans, bethanechol is poorly absorbed from the GI tract, and the onset of action is usually within 30-90 minutes after oral dosing. (elephantcare.org)
  • bethanechol chloride oral : User Ratin. (druginformer.com)
Motility1
Nicotinic1
  • Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. (wikipedia.org)
Detrusor1
Salivation2
  • Symptoms of a bethanechol overdose include abdominal discomfort, increased salivation or watering mouth, flushing or hot feeling of the skin, sweating, nausea, and vomiting. (cigna.com)
  • The side effects of bethanechol may include diarrhea, salivation and sweating due to activation of the M3 receptor while bradycardia due to activation of the M2 receptor. (medicalzone.net)
Side effects9
  • Bethanechol may cause side effects. (medlineplus.gov)
  • What are the possible side effects of bethanechol? (cigna.com)
  • Although there is no specific information comparing use of bethanechol in children with use in other age groups, bethanechol is not expected to cause different side effects or problems in children than it does in adults. (drugs.com)
  • Therefore, patients taking bethanechol for urine retention may manifest side effects such as nausea and vomiting. (proprofs.com)
  • Common side effects of bethanechol include general discomfort, upset stomach, and dizziness. (rxwiki.com)
  • Serious side effects have been reported with bethanechol. (rxwiki.com)
  • This is not a complete list of bethanechol side effects. (rxwiki.com)
  • What side effects can Bethanechol cause? (singhealth.com.sg)
  • A low dose of Bethanechol is often used in treatment as increasing the dose can cause side effects like nausea, diarrhea and headache. (wikipedia.org)
Urine1
  • After administering bethanechol to a patient with urine retention, the nurse in charge monitors the patient for adverse effects. (proprofs.com)
Stimulation1
  • Since bethanechol is a muscarinic receptor stimulator, other effects of muscarinic stimulation will occur. (proprofs.com)
Surgery2
  • Bethanechol chloride is also used by people who have trouble urinating after surgery or after delivering a baby. (medbroadcast.com)
  • Bethanechol is contraindicated in patients who are allergic to the drug, with history of asthma, peptic ulcer, intestinal or urinary obstruction, following recent gastrointestinal or urinary surgery, decreased heart rate and low blood pressure, epilepsy, Parkinsonism, coronary heart disease and overactive thyroid. (medindia.net)
Synthetic2
  • Chemistry - A synthetic cholinergic ester, bethanechol occurs as a slightly hygroscopic, white or colorless crystalline powder with a slight, amine-like or "fishy" odor. (elephantcare.org)
  • Bethanechol is a synthetic muscarinic stimulant. (medscape.com)
Hydrolyzed by cholinesterase1
  • Unlike acetylcholine, bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action. (wikipedia.org)
Dose1
  • The dose of bethanechol will be different for different patients. (drugs.com)
Precautions1
Muscarinic receptor1
  • Use of bethanechol, as well as all other muscarinic receptor agonists, is contraindicated in patients with asthma, coronary insufficiency, peptic ulcers, intestinal obstruction and hyperthyroidism. (wikipedia.org)
Cross the blood-brain b2
  • Bethanechol chloride does not cross the blood-brain barrier because of its charged quaternary amine moiety. (nih.gov)
  • Bethanechol will not react with muscarinic 1 receptor (M1) on the central nervous system due to bethanechol inability to cross the blood brain barrier. (medicalzone.net)
Nausea1
  • Administer bethanechol on an empty stomach (i.e., 1 hour before or 2 hours after a meal) to minimize nausea and vomiting. (pdr.net)
Diltiazem2
  • In the second and third studies diltiazem and bethanechol gels of increasing concentration were applied topically to lower anal pressure. (bmj.com)
  • 2% diltiazem produced a maximal 28% reduction, and 0.1% bethanechol a maximal 24% reduction, the effect lasting three to five hours. (bmj.com)
Cause dizziness2
  • Bethanechol may cause dizziness or fainting, especially when you rise from a sitting or lying position. (cigna.com)
  • Bethanechol may cause dizziness. (cigna.com)
Inability1
  • inability to sleep or sleeping too much, buy bethanechol bars cheap cheap bethanechol online without rx remove residue buildup around the base of the hair, This article will tell you more about it. (aircus.com)
Parasympathomimetic1
  • Bethanechol is a parasympathomimetic choline ester, a drug that has a stimulating effect on muscarinic receptors which are responsible for the contraction of the smooth muscle tone. (medicalook.com)
Https2
  • https://www.ema.europa.eu/documents/psusa/bethanechol-list-nationally-authorised-medicinal-products-psusa/00000402/202006_en.pdf Gorsky M, Epstein JB, Parry J, Epstein MS, Le ND, Silverman S (February 2004). (wikipedia.org)
  • 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547017/6/Bethanechol. (hopkinsguides.com)
Obstruction1
  • Bethanechol should be used to treat these disorders only after mechanical obstruction is ruled out as a possible cause. (wikipedia.org)
Generic11
  • The generic ingredient in BETHANECHOL CHLORIDE is bethanechol chloride . (drugpatentwatch.com)
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Medicines1
  • When you are taking bethanechol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. (drugs.com)