Effect of amodiaquine on gastric histamine methyltransferase and on histamine-stimulated gastric secretion. (1/2)
1 Amodiaquine was found to be a potent inhibitor in vitro of gastric histamine methyltransferase from human and canine corpus and from pig antrum. The ID50 for the enzyme, purified from pig antrum mucosa by ultracentrifugation and chromatography on DEAE-cellulose, was 2.5 muM. 2 In six dogs with Heidenhanin pouches the maximum secretory response to histamine (40 mug/kg i.m.) was augmented by i.m. injection of amodiaquine. The augmentation depended on the dose of amodiaquine, the optimum effect (40% increase in volume of gastric juice, 80% in acid output) being achieved with 2 mg/kg. The maximum secretory response to betazole was also enhanced by amodiaquine. 3 It was suggested that amodiaquine may enhance the histamine and betazole stimulated gastric secretion by an inhibition of gastric histamine methyltransferase in vivo. (+info)Pathophysiological responses to meals in the Zollinger-Ellison syndrome: I. Paradoxical postprandial inhibition of gastric secretion. (2/2)
The gastric acid, pepsin, and secretory volume output in response to a mixed meal were measured in six patients with Zollinger-Ellison syndrome caused by a gastrin-producing tumour proved subsequently at surgery. The patients were all normocalcaemic, and none had previous abdominal surgery. In four of the six patients, ingestion of the meal markedly inhibited the gastric secretory output, which decreased to below fasting levels, returning later to basal values. In two other patients, whose fasting acid output was considerably lower, the secretory output increased after the meal, but some inhibiton of gastric secretion was also apparent for variable intervals of time. The serum gastrin concentration in all patients remained essentially unchanged or increased after the meal. Two patients were restudied after successful removal of the duodenal gastrin-producing tumour, and in each the normal gastric secretory and gastrin-releasing responses were completely restored. Our studies suggest that, in patients with the Zollinger-Ellison syndrome caused by a gastrinoma, physiological regulatory mechanisms triggered by food reduce the continuous stimulation of gastric secretion caused by their tumoural hypergastrinaemia. (+info)Betazole is a medication used to treat certain types of skin conditions, such as psoriasis and eczema.
Betazole is a medication that is used to treat certain types of skin conditions, such as psoriasis and eczema. It is a topical cream or ointment that is applied to the affected area of the skin. Betazole works by reducing inflammation and slowing down the growth of skin cells, which can help to improve the appearance of the skin and reduce symptoms such as itching and redness. It is usually applied once or twice a day, and the dosage and duration of treatment will depend on the specific condition being treated and the individual patient. Betazole is generally considered to be safe and effective when used as directed, but it can cause side effects such as skin irritation, burning, or redness. It is important to follow the instructions provided by your healthcare provider and to report any side effects to them.
Betazole
... (also known as ametazole) is a histamine H2 receptor agonist. Betazole hydrochloride is known as gastramine and ... Betazole is used as a stimulant in preference to histamine because of its specificity for the H2 receptor and its advantage of ... The volume of acid secretion is measured following administration of betazole, diagnosis being secretion greater than 60% of ... Hammond JB, Offen WW (1988). "Effect of nizatidine and cimetidine on betazole-stimulated gastric secretion of normal subjects: ...
Histamine H2 receptor
The drug betazole is an example of a histamine H2 receptor agonist. Histamine is a ubiquitous messenger molecule released from ...
Histamine agonist
H2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H3: Betahistine is a weak ...
Pyrazole
In medicine, derivatives of pyrazole are widely used, including celecoxib and similar COX-2 inhibitors, zaleplon, betazole, and ...
List of MeSH codes (D03)
... betazole MeSH D03.383.129.539.120 - 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)-1h-pyrazol-3-amine MeSH D03.383.129.539.200 - ...
C5H9N3
The molecular formula C5H9N3 (molar mass: 111.15 g/mol, exact mass: 111.0796 u) may refer to: Betazole (also called ametazole) ...
ATC code V04
V04CF01 Tuberculin V04CG01 Cation exchange resins V04CG02 Betazole V04CG03 Histamine phosphate V04CG04 Pentagastrin V04CG05 ...
List of drugs: Be
Betaxon Betazole (INN) Bethanechol (INN) Betiatide (INN) Betimol Betnesol Betnovate Betoptic Pilo Betoptic S Betoxycaine (INN) ...
Bromazepam
Stacher G, Stärker D (February 1974). "Inhibitory effect of bromazepam on basal and betazole-stimulated gastric acid secretion ...
Betazole - Wikipedia
Betazole (also known as ametazole) is a histamine H2 receptor agonist. Betazole hydrochloride is known as gastramine and ... Betazole is used as a stimulant in preference to histamine because of its specificity for the H2 receptor and its advantage of ... The volume of acid secretion is measured following administration of betazole, diagnosis being secretion greater than 60% of ... Hammond JB, Offen WW (1988). "Effect of nizatidine and cimetidine on betazole-stimulated gastric secretion of normal subjects: ...
National Ambulatory Medical Care Survey, 1994
Antihistamines; Latest Classification of Antihistamine - illnesshacker
Manomet drug & pharmaceuticals. Manomet available forms, doses, prices
When food and betazole were used to stimulate secretion, inhibition of hydrogen ion concentration usually ranged from 45 to 75 ... Betazole. 1.5 mg/kg (sc). 300 mg (po). 85% at 2 ½ hours. ... Intrinsic factor secretion was studied with betazole as a ... Oral Manomet 300 mg inhibited the rise in intrinsic factor concentration produced by betazole, but some intrinsic factor was ... Oral Manomet significantly inhibited gastric acid secretion stimulated by betazole (an isomer of histamine), pentagastrin, ...
DrugBase: ATC-Code
Rupatadine - wikidoc
Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H1 receptor antagonist activity. It further blocks the receptors of the platelet-activating factor (PAF) according to in vitro and in vivo studies.[2] Rupatadine possesses anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli, and inhibition of the release of cytokines, particularly of the TNF in human mast cells and monocytes.[3] ...
XENON PHARMACEUTICALS (PVT) LTD.
Information provided on this Web site is neither intended nor implied to be a substitute for professional medical advice. You should not use this information on this web site or the information on links from this site to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Pharma Professional Services advises you to always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.. You should check with your physician/health care provider before using any of the means or methods presented on this site. If you undertake any treatment methods displayed on this site without such supervision, you are solely and entirely responsible for its outcome. Pharma Professional Services nor anyone connected with this site cannot be held responsible for your actions nor any conditions resulting thereof.. ...
DailyMed - RANITIDINE- ranitidine hydrochloride tablet
Lexical Tools
C67159|Chemotherapy Regimen Used to Treat Childhood Hodgkins Lymphoma|Modify|23-APR-07|(null)|Chemotherapy Regimen Used to...
Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome | eNeuro
Figure 1. Locomotion assay to identify drugs that rescue the scn1Lab mutant epilepsy phenotype. a, Schematic of the phenotype-based screening process. Chemical libraries can be coded and aliquoted in small volumes (75 µL) into individual wells containing one mutant fish. The 96-well microplate is arranged so that six fish are tested per drug; with one row of six fish maintained as an internal control (red circles) on each plate. b, Representative images for WT and scn1Lab mutant zebrafish larvae at 5 dpf. Note the morphological similarity but darker pigmentation in mutant larvae. c, Box plot of mean velocity (in millimeters per second) for two consecutive recordings of mutant larvae in embryo media. Experiments were performed by first placing the mutant larvae in embryo media and obtaining a baseline locomotion response; embryo media was then replaced with new embryo media (to mimic the procedure used for test compounds), and a second locomotion response was obtained. The percentage change in ...
Code System Concept
MeSH Browser
Betazole Dihydrochloride Narrower Concept UI. M0330849. Registry Number. 138-92-1. Terms. Betazole Dihydrochloride Preferred ... Betazole Monohydrochloride Narrower Concept UI. M0330848. Registry Number. 1121-45-5. Terms. Betazole Monohydrochloride ... Betazole Dihydrochloride Betazole Monohydrochloride Histalog Lilly 96791 Pharm Action. Gastrointestinal Agents. Histamine ... Betazole Preferred Concept UI. M0002440. Registry Number. 1C065P542O. Related Numbers. 105-20-4. 1121-45-5. 138-92-1. Scope ...
MeSH Browser
Betazole Dihydrochloride Narrower Concept UI. M0330849. Registry Number. 138-92-1. Terms. Betazole Dihydrochloride Preferred ... Betazole Monohydrochloride Narrower Concept UI. M0330848. Registry Number. 1121-45-5. Terms. Betazole Monohydrochloride ... Betazole Dihydrochloride Betazole Monohydrochloride Histalog Lilly 96791 Pharm Action. Gastrointestinal Agents. Histamine ... Betazole Preferred Concept UI. M0002440. Registry Number. 1C065P542O. Related Numbers. 105-20-4. 1121-45-5. 138-92-1. Scope ...
E0000163|Adriamycin|doxorubicin
Lexical Tools
Glz Total Tablet - Online Pharmacy
Betazole P 40mg Tablet is to be taken empty stomach. How Betazole P Tablet works Betazole P 40mg Tablet is a proton pump ... Dose adjustment of Betazole P 40mg Tablet may be needed. Please consult your doctor. What if you forget to take Betazole P ... Uses of Betazole P Tablet Heartburn Gastroesophageal reflux disease (Acid reflux) Peptic ulcer disease Benefits of Betazole P ... Kidney SAFE IF PRESCRIBED Betazole P 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Betazole ...
ABORTIFACIENT AGENTS ABORTIFACIENT AGENTS
HISTAMINE AGENTS BETAZOLE HISTAMINE AGENTS BROMPHENIRAMINE HISTAMINE AGENTS BURIMAMIDE HISTAMINE AGENTS BUTYRIC ACID HISTAMINE ... AND RENA BETAZOLE HEMATOLOGIC, GASTROINTESTINAL, AND RENA BISACODYL HEMATOLOGIC, GASTROINTESTINAL, AND RENA BISMUTH HEMATOLOGIC ... HISTAMINE AGONISTS BETAZOLE HISTAMINE AGONISTS DIMAPRIT HISTAMINE AGONISTS HISTAMINE AGONISTS HISTAMINE AGONISTS IMPROMIDINE ... GASTROINTESTINAL AGENTS BETAZOLE GASTROINTESTINAL AGENTS BISACODYL GASTROINTESTINAL AGENTS BISMUTH GASTROINTESTINAL AGENTS ...
DeCSSecretion2
- The volume of acid secretion is measured following administration of betazole, diagnosis being secretion greater than 60% of the maximal acid secretion following betazole stimulation. (wikipedia.org)
- Intrinsic factor secretion was studied with betazole as a stimulant. (sdrugs.com)
Stimulant1
- Betazole is used as a stimulant in preference to histamine because of its specificity for the H2 receptor and its advantage of not generating the undesirable side effects that histamine would induce. (wikipedia.org)
Histamine1
- Betazole (also known as ametazole) is a histamine H2 receptor agonist. (wikipedia.org)
Histalog1
- Betazole hydrochloride is known as gastramine and histalog. (wikipedia.org)
Ametazole1
- Betazole (also known as ametazole) is a histamine H2 receptor agonist. (wikipedia.org)
Acid3
- The volume of acid secretion is measured following administration of betazole, diagnosis being secretion greater than 60% of the maximal acid secretion following betazole stimulation. (wikipedia.org)
- Introduction Betazole P 40mg Tablet is a medicine that reduces the amount of acid produced in your stomach. (amazmeds.com)
- Uses of Betazole P Tablet Heartburn Gastroesophageal reflux disease (Acid reflux) Peptic ulcer disease Benefits of Betazole P Tablet In Heartburn Heartburn and acid reflux happens when a muscle above your stomach relaxes too much and allows stomach contents and acid to come back up into your esophagus and mouth. (amazmeds.com)
Effects3
- Betazole is used as a stimulant in preference to histamine because of its specificity for the H2 receptor and its advantage of not generating the undesirable side effects that histamine would induce. (wikipedia.org)
- show more show less Side effects of Betazole P Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. (amazmeds.com)
- Consult your doctor if they persist or if you?re worried about them Common side effects of Betazole P Diarrhea Flatulence Headache Nausea Stomach pain Vomiting Dizziness How to use Betazole P Tablet Take this medicine in the dose and duration as advised by your doctor. (amazmeds.com)
