Betamethasone: A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)Betamethasone Valerate: The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Fetal Organ Maturity: Functional competence of specific organs or body systems of the FETUS in utero.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.Phimosis: A condition in which the FORESKIN cannot be retracted to reveal the GLANS PENIS. It is due to tightness or narrowing of the foreskin opening.Prenatal Exposure Delayed Effects: The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Administration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Clobetasol: A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.Respiratory Distress Syndrome, Newborn: A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.Protective Devices: Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)Pharmaceutical Solutions: Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents. For reasons of their ingredients, method of preparation, or use, they do not fall into another group of products.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Biological Products: Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.Materia Medica: Materials or substances used in the composition of traditional medical remedies. The use of this term in MeSH was formerly restricted to historical articles or those concerned with traditional medicine, but it can also refer to homeopathic remedies. Nosodes are specific types of homeopathic remedies prepared from causal agents or disease products.Health Food: A non-medical term defined by the lay public as a food that has little or no preservatives, which has not undergone major processing, enrichment or refinement and which may be grown without pesticides. (from Segen, The Dictionary of Modern Medicine, 1992)Consumer Product SafetyDermatologic Agents: Drugs used to treat or prevent skin disorders or for the routine care of skin.Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).Beclomethasone: An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA.Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.Diphtheria-Tetanus-Pertussis Vaccine: A vaccine consisting of DIPHTHERIA TOXOID; TETANUS TOXOID; and whole-cell PERTUSSIS VACCINE. The vaccine protects against diphtheria, tetanus, and whooping cough.Rotavirus Vaccines: Vaccines or candidate vaccines used to prevent infection with ROTAVIRUS.Immunization Schedule: Schedule giving optimum times usually for primary and/or secondary immunization.Vaccines, Combined: Two or more vaccines in a single dosage form.Product Labeling: Use of written, printed, or graphic materials upon or accompanying a product or its container or wrapper. It includes purpose, effect, description, directions, hazards, warnings, and other relevant information.Drug Interactions: The action of a drug that may affect the activity, metabolism, or toxicity of another drug.Haplosporida: A phylum of EUKARYOTES in the RHIZARIA group. They are small endoparasites of marine invertebrates. Spores are structurally complex but without polar filaments or tubes.Fluprednisolone: A synthetic glucocorticoid with anti-inflammatory properties.TracheitisStreptococcus equi: A species of gram-positive, coccoid bacteria isolated from abscesses in submaxillary glands and mucopurulent discharges of the upper respiratory tract of horses. This organism belongs to Group C streptococci with regards to antigen response and is known to cause strangles. The subspecies S. zooepidemicus is also considered a pathogen of horses.Adrenal Cortex HormonesScalp DermatosesSwimming PoolsFluocinolone Acetonide: A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)Health Resources: Available manpower, facilities, revenue, equipment, and supplies to produce requisite health care and services.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Pharmacies: Facilities for the preparation and dispensing of drugs.Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.Pharmaceutical Services, Online: Pharmacy services accessed via electronic means.Pharmacy: The practice of compounding and dispensing medicinal preparations.Education, Pharmacy: Formal instruction, learning, or training in the preparation, dispensing, and proper utilization of drugs in the field of medicine.Skin DiseasesSkin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.Hemorrhoids: Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.Suppositories: Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.Hemorrhoidectomy: The surgical removal of HEMORRHOIDS.Anal Canal: The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.Proctoscopy: Endoscopic examination, therapy or surgery of the rectum.

Delay of preterm delivery in sheep by omega-3 long-chain polyunsaturates. (1/339)

A positive correlation has been shown between dietary intake of long-chain omega-3 fatty acids in late pregnancy and gestation length in pregnant women and experimental animals. To determine whether omega-3 fatty acids have an effect on preterm labor in sheep, a fish oil concentrate emulsion was continuously infused to six pregnant ewes from 124 days gestational age. At 125 days, betamethasone was administered to the fetus to produce preterm labor. Both the onset of labor and the time of delivery were delayed by the fish oil emulsion. Two of the omega-3-infused ewes reverted from contractions to nonlabor, an effect never previously observed for experimental glucocorticoid-induced preterm labor in sheep. Maternal plasma estradiol and maternal and fetal prostaglandin E2 rose in control ewes but not in those infused with omega-3 fatty acid. The ability of omega-3 fatty acids to delay premature delivery in sheep indicates their possible use as tocolytics in humans. Premature labor is the major cause of neonatal death and long-term disability, and these studies present information that may lead to a novel therapeutic regimen for the prevention of preterm delivery in human pregnancy.  (+info)

Secondary glioblastoma remarkably reduced by steroid administration after anaplastic transformation from gliomatosis cerebri--case report. (2/339)

A 45-year-old female presented with gliomatosis cerebri manifesting as hemiballismus-like involuntary movement in the arm, motor weakness in the leg, and hypesthesia in her left side. Computed tomography showed only diffuse swelling of the right cerebral hemisphere, but T2-weighted magnetic resonance imaging revealed a diffuse lesion spreading from the right thalamus to the temporal, parietal, and occipital lobes on the same side. No abnormal enhancement was recognized. Cerebral angiography showed no specific finding. A right occipital lobectomy was performed to confirm the diagnosis of gliomatosis cerebri. Anaplastic transformation was recognized 5 months later. The disease did not resolve with radiation or interferon administration, but steroid therapy achieved remarkably effective tumor regression. The patient died due to pneumonia. Autopsy showed the features of diffuse glioblastoma. Steroid therapy may be an effective treatment for gliomatosis cerebri before the terminal stage.  (+info)

Betamethasone-mediated vascular dysfunction and changes in hematological profile in the ovine fetus. (3/339)

Glucocorticoid administration to fetal sheep induces a sustained systemic blood pressure rise and an associated increase in femoral vascular resistance. We utilized a small vessel myograph to compare isometric vascular responses of small femoral arterial branches from fetal sheep infused intravenously with either betamethasone or vehicle in vivo from 128 days gestation. Changes in hematological parameters were also determined. Betamethasone was infused for 48 h to produce fetal plasma betamethasone concentrations similar to those observed in human fetuses after maternal treatment with betamethasone to accelerate fetal lung maturation. When compared with vessels removed from vehicle-infused fetuses, vessels obtained from betamethasone-treated fetuses exhibited 1) enhanced sensitivity to depolarizing potassium solutions; 2) no differences in response to the thromboxane mimetic U-46619 or norepinephrine; and 3) differential responses to vasodilators, enhanced sensitivity to ACh, but decreased response to bradykinin and forskolin. In addition, erythrocyte and leukocyte counts were increased in betamethasone-infused fetuses. These observations indicate that multiple mechanisms operate to increase fetal vascular resistance during antenatal betamethasone exposure.  (+info)

Concentration of steroids in bovine peripheral plasma during the oestrous cycle and the effect of betamethasone treatment. (4/339)

Testosterone, oestradiol and progesterone were measured in peripheral plasma during the oestrous cycle of 6 heifers. Oestradiol and progesterone results confirmed earlier reports. Concentration of testosterone on the day of oestrus was 40+/-3 pg/ml (mean+/-S.E.M.), and two peaks were detected during the cycle, one 7 days before oestrus (1809+/-603 pg/ml) and the other (78+/- 7 pg/ml) on the day before the onset of oestrus. The concentration of progesterone declined in most cases 1 day after the maximum concentration of testosterone. Betamethasone treatment in 5 heifers extended luteal function by an average of 10 days: plasma androstenedione and oestradiol concentrations were unaltered; cortisol values were depressed for at least 16 days after treatment; testosterone concentrations were lowered by 13+/-2-4% during treatment, and except in one heifer the peak on Day -7 was abolished.  (+info)

Functional capacity of fetal zone cells of the baboon fetal adrenal gland: a major source of alpha-inhibin. (5/339)

We have shown that ACTH receptor mRNA expression and steroidogenesis were increased in the transitional zone and decreased in the fetal zone of the baboon fetal adrenal in the second half of gestation. Thus, we proposed that there is a divergence in ACTH receptor-mediated zone-specific steroidogenesis within the fetal adrenal during mid to late gestation. We have also demonstrated that fetal serum alpha-inhibin levels decline with advancing development. It is possible, therefore, that the alpha subunit of inhibin provides a good marker of fetal zone cellular function and that the changes in circulating fetal alpha-inhibin with advancing pregnancy reflect ontogenetic changes in fetal adrenal cortical zone-specific cell function. However, it remains to be determined whether the fetal adrenal is a major source of circulating alpha-inhibin in the fetus and whether alpha-inhibin is expressed in the fetal, definitive, and/or transitional zones. Therefore, the current study compared fetal serum alpha-inhibin levels with immunocytochemical localization of alpha-inhibin in baboon fetal adrenals obtained on Days 60 (early), 100 (mid), and 165 or 182 (late) of gestation (term averages Day 184) from animals untreated or treated with betamethasone, which we previously demonstrated suppressed fetal pituitary ACTH and adrenal weight. Fetal serum alpha-inhibin levels (mean +/- SE) were greater (p < 0.05) at mid (5863 +/- 730 microliter eq/ml) than at late (3246 +/- 379) gestation and were reduced (p < 0. 05) by betamethasone. The inhibin alpha subunit was expressed in abundant quantities in the fetal adrenal cortex, but not in medulla, throughout gestation. At mid and late gestation, alpha-inhibin was expressed throughout the fetal adrenal cortex but most intensely in the innermost area of fetal zone cells. By late gestation, the fetal adrenal exhibited a gradient of alpha-inhibin expression. Thus, the outermost definitive zone cells were devoid of alpha-inhibin, the transitional zone exhibited a relatively low alpha-inhibin content, and fetal zone cells continued to exhibit extensive expression of alpha-inhibin. Betamethasone diminished the intensity of alpha-inhibin expression throughout the fetal adrenal cortex. These results indicate that the fetal adrenal fetal zone is a significant source of circulating alpha-inhibin in the baboon fetus and that alpha-inhibin provides a good marker to study the developmental regulation of fetal zone-specific adrenocortical function.  (+info)

Spontaneous labour at term is associated with fetal monocyte activation. (6/339)

The aetiology of both term and preterm labour remains incompletely understood. Maternal infectious diseases as well as intra-uterine infections were shown to be a well established cause of uncontrollable preterm delivery, indicating that inflammatory reactions, regulated by maternal immunecompetent cells, are implicated in labour-promoting mechanisms. To investigate the possibility that the activation of the fetal immune system may be involved in labour induction, we examined cytokine production patterns of different cord blood cell populations obtained from neonates after spontaneous onset of normal term labour and vaginal delivery (n = 25), vaginal delivery but induced term labour (n = 17), and preterm delivery because of uncontrollable labour (n = 27, 20 patients received corticoid treatment for fetal lung maturation), in comparison with cells obtained from neonates after elective term caesarean delivery in the absence of labour (n = 15). Our results demonstrate that spontaneous term labour, but not induced term labour, was associated with significantly increased IL-6 production by myelomonocytic cell populations. Preterm delivery due to uncontrollable labour with resistance to tocolysis was not associated with increased IL-6 production by fetal myelomonocytic cells. Two-colour flow cytometry combined with intracellular cytokine staining was used to identify fetal monocytes as sources of labour-associated IL-6 release at term. We did not find any activation of cord blood T cells in association with spontaneous term or uncontrollable preterm labour. Therefore, fetal T cell responses may not cause monocyte activation. Our results suggest that increased release of IL-6 from fetal monocytes is involved in mechanisms promoting normal term, but not preterm labour, and that mechanisms inducing term and preterm labour are completely different.  (+info)

Developmental expression of and effect of betamethasone on the messenger ribonucleic acid levels for peptide growth factors in the baboon fetal adrenal gland. (7/339)

In the present study, we determined whether expression of the messenger ribonucleic acids (mRNAs) for insulin-like growth factor-II (IGF-II), and its principal IGF type-1 receptor and IGF-binding protein-2 (IGFBP-2), as well as basic fibroblast growth factor (bFGF), was developmentally regulated in the baboon fetal adrenal gland. In the second phase of this study, fetal pituitary ACTH was suppressed by the administration of betamethasone to determine the possible effect on the mRNA levels for those factors, i.e. IGF-II and IGFBP-2, shown to be expressed at high levels in the adrenal late in fetal development. Adrenals were obtained from fetuses delivered via Cesarean section on days 60 (early), 100 (mid), and 165 (late) of gestation (term=184 days) from untreated baboons and on day 165 from baboons in which betamethasone was administered to the fetus, or to fetus and mother, every other day between days 150 and 164 of gestation. Although the mRNA levels of IGF-II in the fetal adrenal were similar at early, mid and late gestation, IGF type-1 receptor mRNA levels were approximately 2- to 3-fold greater (P<0.01) at mid than at early or late gestation. In contrast, there was an increase (P<0.001) in fetal adrenal IGFBP-2 and bFGF mRNA levels in late gestation. Although fetal adrenal weights and width of the zone of definitive/transitional cells exhibiting immunocytochemical staining for Delta(5)-3beta-hydroxysteroid dehydrogenase (3beta-HSD) were markedly suppressed (P<0.01) by the administration of betamethasone, IGF-II and IGFBP-2 mRNA expression was not decreased. In summary, very different patterns of mRNA levels for IGF-II, IGF type-1 receptor, IGFBP-2 and bFGF were exhibited in the developing baboon fetal adrenal gland, which may reflect functionally important differences in their respective cellular localization within the cortex, as well as a divergence in the functional development of the fetal, transitional and definitive zones of the baboon fetal adrenal cortex.  (+info)

Antenatal glucocorticoid treatment and cystic periventricular leukomalacia in very premature infants. (8/339)

BACKGROUND: Antenatal glucocorticoid therapy decreases the incidence of several complications among very premature infants. However, its effect on the occurrence of cystic periventricular leukomalacia, a major cause of cerebral palsy, remains unknown. METHODS: We retrospectively analyzed a cohort of 883 live-born infants, with gestational ages ranging from 24 to 31 weeks, who were born between January 1993 and December 1996 at three perinatal centers in the Paris area. The mothers of 361 infants had received betamethasone before delivery, the mothers of 165 infants had received dexamethasone before delivery, and the mothers of 357 infants did not receive glucocorticoids. We compared the rates of cystic periventricular leukomalacia among the three groups of infants in bivariate and multivariate analyses after adjustment for confounding factors. RESULTS: The rate of cystic periventricular leukomalacia was 4.4 percent among the infants whose mothers had received betamethasone, 11.0 percent among the infants whose mothers had received dexamethasone, and 8.4 percent among the infants whose mothers had not received a glucocorticoid. After adjustment for gestational age, the mode of delivery, and the presence or absence of chorioamnionitis, prolonged interval between the rupture of membranes and delivery (>24 hours), preeclampsia, and the use of tocolytic drugs, antenatal exposure to betamethasone was associated with a lower risk of cystic periventricular leukomalacia than was either the absence of glucocorticoid therapy (adjusted odds ratio, 0.5; 95 percent confidence interval, 0.2 to 0.9) or exposure to dexamethasone (adjusted odds ratio, 0.3; 95 percent confidence interval, 0.1 to 0.7). The adjusted odds ratio for the group of infants whose mothers had received dexamethasone as compared with the group of infants whose mothers had not received a glucocorticoid was 1.5 (95 percent confidence interval, 0.8 to 2.9). CONCLUSIONS: Antenatal exposure to betamethasone but not dexamethasone is associated with a decreased risk of cystic periventricular leukomalacia among very premature infants.  (+info)

*Lotion

"Betamethasone (Topical)". Lexicomp Online. Hudson, OH: Lexi-Comp, Inc. April 21, 2017. Retrieved April 25, 2017. Sanders, ...

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In pharmacy, a thermophobic foam consisting of 0.1% betamethasone valerate was found to be at least as effective as ... August 4, 2003). "Efficacy of Betamethasone Valerate 0.1% Thermophobic Foam". Curr Med Res Opin. 19 (4): 342-5. doi:10.1185/ ...

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Alclometasone dipropionate, betamethasone dipropionate, betamethasone valerate, clobetasol propionate, clobetasone butyrate, ... Beclometasone, betamethasone, dexamethasone, fluocortolone, halometasone, and mometasone. ...

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It contains betamethasone valerate as an anti-inflammatory. Banamine - A non-steroidal anti-inflammatory drug (NSAID) used in ...

*Alejandro Marque

However, Marque tested positive for Betamethasone during the race. Marque claimed that the UCI had known about the use of the ...

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In 2009 he was found guilty of betamethasone doping. The sample was delivered on 22 May 2008 in an in-of-competition test in ...

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... clobetasol and betamethasone. Suppressing the immune system with corticosteroids helps by decreasing the number of antibodies ...

*Anne Anderson (researcher)

"Placental transfer and metabolism of betamethasone in human pregnancy". Obstet Gynecol. 49 (4): 471-474. PMID 857211. Anderson ...

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Betamethasone, on the other hand, is preferred over dexamethasone because it is thought to have better prophylaxis of brain ... Dexamethasone and betamethasone are the corticosteroids used for the purpose although the former is recommended over the latter ... "Dexamethasone versus betamethasone as an antenatal corticosteroid (ACS)" (PDF). UN Commission / Born Too soon Care Antenatal ... Treatment consists of 2 doses of 12 mg of betamethasone given intramuscularly 24 hours apart or 4 doses of 6 mg of ...

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Commonly used solutions are of fluorometholone, medrysone, betamethasone or dexamethasone. Mast cell stabilizers such as sodium ...

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Prescribed treatments include: topical creams such as Tacrolimus and Betamethasone. systemic immunosuppressants such as ...

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The active ingredients of are gentamicin, betamethasone valerate and clotrimazole. Otomax is used for treatment of acute ...

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Kin, KC; Hill, D; Feldman, SR (June 2016). "Calcipotriene and betamethasone dipropionate for the topical treatment of plaque ...

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"Enstilar (calcipotriene and betamethasone dipropionate) Foam, 0.005%/0.064% for topical use. Full Prescribing Information" (PDF ...

*Ecchymosis

The medication betamethasone can have the adverse effect of causing echhymosis. The word ecchymosis (/ˌɛkɪˈmoʊsɪs/; plural ...

*Ludger Beerbaum

However, following the competition, Goldfever tested positive for the prohibited substance betamethasone. The International ...

*Emanuel Molina

He tested positive for betamethasone, a substance that was banned in 2016. However, both the player and the club claimed Molina ...

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... betamethasone cream in treating dermatitis, though both were well-tolerated with no systemic adverse effects reported. Galbiati ... versus betamethasone dipropionate". Zeitschrift für Hautkrankheiten. 58 (4): 230-7. PMID 6342285. ...

*List of drugs known for off-label use

Dexamethasone and Betamethasone in premature labor, to enhance pulmonary maturation of the fetus. Doxepin has been used to ...

*List of 2004 Summer Olympics medal winners

... later tested positive for the banned substance betamethasone. Upon being found guilty of riding a drugged horse, the ...

*Domoprednate

A double-blind, randomized comparison with hydrocortisone butyrate, betamethasone valerate, clobetasole propionate and placebo ... betamethasone valerate ointment. A double-blind, randomized trial". Dermatologica. 170 (4): 195-8. PMID 3888709. Schmidt H, ...

*Cheilitis

"Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline". ...

*Mouthwash

Acts as a buffer Betamethasone is sometimes used as an anti-inflammatory, corticosteroid mouthwash. It may be used for severe ...

*Darier's disease

Ciclosporin and prescription-only topical corticosteroids, e.g., betamethasone, have been used during acute flares. Some ...

*Tinea incognito

These combinations include betamethasone dipropionate and clotrimazole (trade name Lotrisone) and triamcinolone acetonide and ...

*Diflorasone diacetate

Shupack, J. L.; Jondreau, L.; Kenny, C.; Stiller, M. J. (1993). "Diflorasone diacetate ointment 0.05% versus betamethasone ...
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LEMUS, DAVID et al. Antiangiogenic effect of betamethasone on the chick cam stimulated by TA3 tumor supernatant. Biol. Res. [online]. 2001, vol.34, n.3-4, pp.227-236. ISSN 0716-9760. http://dx.doi.org/10.4067/S0716-97602001000300010.. Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: ß-MAAC). Methylcellulose discs instilled with 10 µl of ß-MAAC (0.08 µg/ml),10 µl of tumor supernatant(TA3ts),5 µl ß-MAAC + 5 µl TA3ts, and 10 µl of PBS as control were implanted in host chick eggs. On day 12, the grafts were removed, photographed and fixed. Sections were stained in parallel, one and three with hematoxylin-eosin, and section two by the Tunel method. The number of vessels was evaluated in a microscopic field of the CAM (2250 µm2 ). The results show that ß-MAAC produced a significant ...
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Chang, Y-Lung.; Chang, S-Dyh.; Chao, A-Shine.; Hsieh, P.C.C.; Wang, C-Nin.; Wang, T-Hao., 2012: Placenta share discordance and umbilical artery Doppler change after antenatal betamethasone administration in monochorionic twins with selective intrauterine growth restriction: is there a link?
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A simple RP HPLC method for quantification of betamethasone dipropionate (BDP) in gingival crevicular fluid (GCF) has been developed and validated. GCF represents a valuable matrix for therapeutic monitoring of drugs used in the treatment of periodontal disease. The proposed method involves single step extraction for sample preparation. The calibration curve for BDP was linear over the concentration range of 0.10-2.00 μg mL-1 (R2 = 0.9971). RSD values of intra- and inter-day precision ranged 2.2-4.5 and 1.6-5.7 %, while accuracy values were higher than 96.6 and 97.0 %, respectively. The described method can be successfully applied for determination of betamethasone concentrations in GCF obtained from patients with chronic periodontitis after local treatment with BDP cream 0.5 mg g-1. ...
PURPOSE: The aim of the study was to evaluate the effect of perioperatively systemically administered betamethasone on nerve recovery (within or outside a confined space) after induced nerve crush injury. MATERIALS AND METHODS: The sciatic nerve of 40 adult Wistar rats was crushed. In half of the animals, the injured nerve was entrapped in a silicone tube to simulate the environment of a closed space, and in the other half the nerve was left to heal. Half of the rats in each group were treated with subcutaneous betamethasone (2 mg/kg body weight/day) during the first 24 hours, starting preoperatively, whereas the other half, the control animals, were given the same amount of physiological saline. All animals underwent preoperative and postoperative walking track analysis (toe spread [TS] and intermediate toe spread [ITS]) twice weekly for 6 weeks. RESULTS: For nonconfined space groups, there was no significant difference between the 2 groups (P = .052 for ITS and P = .315 for TS) during the ...
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This study will compare efficacy and safety of once daily treatment of calcipotriol plus betamethasone dipropionate gel (LEO 80185) with tacalcitol ointment and LEO 80185 vehicle alone in subjects with psoriasis vulgaris. Subjects will be treated for up to 8 weeks followed by an observation period of up to 8 weeks to investigate the occurence and the time to relapse and occurence of rebound after discontinuation of the investigational products. Only subjects with controlled disease will be considered for this observation phase of the study. Controlled disease is defined as Clear or Almost Clear severity category based on Investigators global assessment (IGA ...
This study will compare efficacy and safety of once daily treatment of calcipotriol plus betamethasone dipropionate gel (LEO 80185) with tacalcitol ointment and LEO 80185 vehicle alone in subjects with psoriasis vulgaris. Subjects will be treated for up to 8 weeks followed by an observation period of up to 8 weeks to investigate the occurence and the time to relapse and occurence of rebound after discontinuation of the investigational products. Only subjects with controlled disease will be considered for this observation phase of the study. Controlled disease is defined as Clear or Almost Clear severity category based on Investigators global assessment (IGA ...
Betamethasone: Betamethasone is a glucocorticoid receptor agonist. This leads to changes in genetic expression once this complex binds to the GRE. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Betamethasone binds to plasma transcortin, and it becomes active when it is not bound to transcortin ...
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Erratum to: Calcipotriol Plus Betamethasone Dipropionate Aerosol Foam in Patients with Moderate-to-Severe Psoriasis: Sub-Group Analysis of the PSO-ABLE ...
Glucocorticoids appear to play an integral role in stimulating surfactant synthesis by activating the rate-regulatory enzyme for phosphatidylcholine synthesis, CTP:cholinephosphate cytidylyltransferase (CT). The activity of liver CT, in vitro, has been shown to be inhibited by the sphingomyelin hydrolysis product, sphingosine. In order to investigate the mechanisms by which glucocorticoids alter CT activity, in vivo, we administered betamethasone (1 mg/kg intraperitoneally) sequentially to adult male rats for 5 days. Betamethasone increased CT activity 2-fold relative to control in whole lung. The hormone also increased membrane-bound activity, but did not affect cytosolic enzyme activity. Betamethasone modestly increased CT mRNA as determined by the reverse-transcription PCR and Southern analysis of PCR products, but did not alter the levels of immunoreactive enzyme in lung membranes as demonstrated by Western blotting. The hormone did, however, produce a nearly 3-fold increase in ...
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View drug interactions between betamethasone and betamethasone topical. These medicines may also interact with certain foods or diseases.
Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other minor skin conditions such as eczema.
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Betamethasone Dipropionate (bay-ta-METH-a-sone dye-PROE-pee-oh-nate) Treats skin pain, swelling, and itching. This medicine is a corticosteroid.
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Betamethasone dipropionate adalah steroid glucocorticoid dengan kebolehan anti-radang dan imunosupresif. Ia digunakan sebagai krim topikal, salap, losyen atau gel (Diprolene) untuk merawat gatal-gatal dan lain-lain keadaan kulit yang kecil seperti ekzema.
Also known as diprosone or diprolene, betamethasone dipropionate is a topical glucocorticoid used as an anti-inflammatory drug. It is used to treat skin conditions and allergies as it helps to suppress the immune responses. Learn more here.
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This part of the eMedTV site offers some basic information on calcipotriene/betamethasone dipropionate, a drug used to treat plaque psoriasis. This Web page takes a quick look at this medication and provides a link to more details.
FDA approval history for Enstilar (betamethasone dipropionate and calcipotriene) used to treat Plaque Psoriasis. Supplied by LEO Pharma
Indications for ENSTILAR (calcipotriene and betamethasone dipropionate aerosol, foam) refers to the medical reasons for why ENSTILAR is used and recommended as a treatment.
As this eMedTV page explains, it is not possible to know if you will have side effects with calcipotriene/betamethasone dipropionate before starting treatment, so you need to report anything unusual. A list of commonly reported problems is also included.
Learn about Betamethasone Dipropionate (Alphatrex, Maxivate and Diprosone), dosing, proper use and what to know before beginning treatment
485805-18-3 - CNXNMLQATFFYLX-ICTDYHGOSA-N - Betamethasone dipropionate mixture with calcipotriene - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Preterm birth is associated with increased risk of type 2 diabetes (T2D) in adulthood; however, the underlying mechanisms are poorly understood. We therefore investigated the effect of preterm birth at ~0.9 of term after antenatal maternal betamethasone on insulin sensitivity, secretion and key determinants in adulthood, in a clinically relevant animal model. Glucose tolerance and insulin secretion (intravenous glucose tolerance test) and whole-body insulin sensitivity (hyperinsulinaemic euglycaemic clamp) were measured and tissue collected in young adult sheep (14 months old) after epostane-induced preterm (9M, 7F) or term delivery (11M, 6F). Glucose tolerance and disposition, insulin secretion, β-cell mass and insulin sensitivity did not differ between term and preterm sheep. Hepatic PRKAG2 expression was greater in preterm than in term males (P = 0.028), but did not differ between preterm and term females. In skeletal muscle, SLC2A4 (P = 0.019), PRKAA2 (P = 0.021) and PRKAG2 (P = 0.049) ...
Title: Understanding the effects of betamethasone on the extensor digitorum longus in fetal guinea pigs. Description: Glucocorticoids are steroid hormones that trigger cellular differentiation during animal development. Pregnant women at risk for preterm births are commonly administered synthetic glucocorticoids, such as betamethasone, in order to accelerate tissue maturation, and consequently increase the survival rate of premature newborns. A great deal of research shows the effects of prenatal steroids on lung tissue; however, the effects on breathing muscles remain unexplored. My research focused on studying the extensor digitorum longus muscle of fetal guinea pigs when exposed to betamethasone. In particular, I examined changes in protein expression of different myosin heavy chain isoforms by running SDS polyacrylamide gels.. ...
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Betamethasone - The patients had been in hospital for some time under satisfactory conditions, the majority of them being treated in the open air on the balcony, where they were in as good circumstances as in a sanatorium.
Prenatal contact with corticosteroids has long-term postnatal neurodevelopmental and somatic consequences. of spasms indicates that prenatal betamethasone publicity down-regulates genes encoding a number of important protein taking part in GABAergic and glutamatergic transmission. Interestingly, there have been significant sex-specific modifications after prenatal betamethasone in synapse-related gene manifestation but no such sex variations were within prenatally saline-injected settings. A pair-wise relevance evaluation revealed that, even though synapse gene manifestation in settings was 3rd party of sex, these genes type topologically specific gene materials in men and women and these materials are modified by betamethasone inside a sex-specific way. These findings may explain the sex differences in both regular occurrence and behavior and severity of infantile spasms. Adjustments in transcript manifestation and their coordination may donate to a molecular PA-824 substrate of long term ...
Topical anti-inflammatory drugs have been used very common in various inflammatory skin disorders, especially atopic dermatitis. However, it is little known about the effect of these drugs in canine skin barrier function. The aim of the present study was to evaluate the effect of 0.05% clobetasol-17-propionate, 0.1% tacrolimus, 0.2% cyclosporine and betamethasone on normal canine skin using non-invasive methods. Five beagles were involved and skin of the back of each dog was topically applied with those drugs once a day for 9 days. Transepidermal water loss (TEWL), skin hydration, skin pH and thickness were assessed every day during experimental periods. TEWL was significantly increased by 0.05% clobetasol-17-propionate and cyclosporine on 9 days (p,0.05). Skin pH was significantly decreased by cyclosporine and tacrolimus on 6 days and 9 days, respectively (p,0.05). Betamethasone gradually decreased skin pH until 9 days. On 6 and 9 days skin hydration was significantly increased in cyclosporine ...
Thirty patients with first episode disciform keratitis and with no previous steroid exposure were randomly assigned to double blind treatment with 3% acyclovir ointment and 0.1% betamethasone (Betnesol) drops or acyclovir ointment and matching placebo. In the steroid group 14 of the 15 patients healed in a mean time of 21.8 days. In the placebo group eight of the 13 patients healed in a mean time of 34.5 days. The difference in mean healing time between the two groups was significant (p , 0.05). The cumulative rate of healing was also quicker in the steroid group when compared with the placebo group (p , 0.001). Other clinical parameters improved more favourably in the combination treatment group. Four patients, two in either group, experienced a mild transient punctate epitheliopathy, but no other serious adverse effects were noted. There has been no significant difference in the recurrence rate between the two groups after a mean follow-up period of approximately 3 years. ...
Betamethasone Dipropionate (bay-ta-METH-a-sone dye-PROE-pee-oh-nate), Calcipotriene (kal-si-poe-TRYE-een) Treats plaque psoriasis. This medicine is a combination of a steroid and vitamin D. Brand Name(s): Enstilar, Taclonex, Taclonex Scalp
OBJECTIVE: Our aim was to study the hemodynamic effects of betamethasone on fetuses with intrauterine growth restriction (IUGR) with absent or reversed end-diastolic (ARED) umbilical artery flow. STUDY DESIGN: Color/pulsed Doppler waveforms were obta
Have you tried icing your neck? I always need to do that the first day after I have injections. 20 minutes every hour. Also, you can check with your PM, but probably tomorrow you could take Advil or something. PLEASE do double check with your doc, though since I know that in certain cases people have to wait 3-7 days after injections before taking any anti-inflammatories ...
BACKGROUND: One course of antenatal corticosteroids reduces the risk of respiratory distress syndrome and neonatal death. Weekly doses given to women who remain undelivered after a single course may have benefits (less respiratory morbidity) or cause harm (reduced growth in utero). We aimed to find out whether multiple courses of antenatal corticosteroids would reduce neonatal morbidity and mortality without adversely affecting fetal growth. METHODS: 1858 women at 25-32 weeks gestation who remained undelivered 14-21 days after an initial course of antenatal corticosteroids and continued to be at high risk of preterm birth were randomly assigned to multiple courses of antenatal corticosteroids (n=937) or placebo (n=921), every 14 days until week 33 or delivery, whichever came first. The primary outcome was a composite of perinatal or neonatal mortality, severe respiratory distress syndrome, intraventricular haemorrhage (grade III or IV), periventricular leucomalacia, bronchopulmonary dysplasia, ...
Beta Val Cream - Betamethasone (bay-ta-METH-a-sone) Valerate is used for Reducing itching, redness, and also for several skin disorders.
Results 1373 Unique joints (ankles, elbows, knees, metacarpophalangeal (MCP), metatarsophalangeal, proximal interphalangeal (PIP), shoulders, wrists) were injected during 2 years. 531 Joints received a second injection, and 262 a third. At baseline, the median numbers of injections (dose of betamethasone) was 4 (28 mg), declining to 0 (0 mg) at subsequent visits. At weeks 2, 4 and 6, 50.0%, 58.1% and 61.7% had achieved a EULAR good response. After 1 and 2 years, respectively, 62.3% (95% CI 58.1% to 66.9%) and 55.5% (51.1% to 60.3%) of the joints injected at baseline had not relapsed. All joint areas had good 2-year joint injection survival, longest for the PIP joints: 73.7% (79.4% to 95.3%). 2-Year joint injection survival was higher for first injections: 56.6% (53.7% to 59.8%) than for the second: 43.4% (38.4% to 49.0%) and the third: 31.3% (25.0% to 39.3%). Adverse events were mild and transient. A high MRI synovitis score of MCP joints and anti-CCP-negativity were associated with poorer joint ...
Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Ebner on betamethasone injectable suspension dosage: Havent heard of any reversal agent for an intramuscular or intradermal injection of a corticosteroid medication like kenalog (triamcinolone). Ones primary care doctor and the doctor who did the injection can work together to help treat side effects, whatever those might be.
Betamethasone is a corticosteroid and anti-inflammatory drug available in a variety of forms (including syrup and foam) for a variety of purposes including the treatment of mouth ulcers and psoriasis.
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Clobetasone (INN) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema, psoriasis and other forms of dermatitis, and ophthalmology. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis. It is available as clobetasone butyrate under the brand names Eumosone or Eumovate both manufactured by GlaxoSmithKline. Trimovate also contains oxytetracycline, an antibiotic, and nystatin, an antifungal. In dermatology, topical clobestasone butyrate helps to reduce the itchiness and erythema associated with eczema and dermatitis. In ophthalmology, clobetasone butyrate 0.1% eye drops have been shown to be safe and effective in the treatment of dry eyes in Sjögrens Syndrome. Sjögrens Syndrome is an autoimmune disorder that affects the moisture producing glands of the body causing many symptoms including dry eyes. When compared to other corticosteroid eye drops; clobetasone butyrate showed only minimal rises in ...
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Since the great majority of patients possess immune response to herpes simplex virus (HSV), the influence of a topical anti-inflammatory corticosteroid (0.1% clobetasone butyrate) on ulcerative herpetic keratitis was studied in rabbits with a previous HSV skin infection (immunised) and compared with that in normal rabbits. Corticosteroid treatment had a much greater ulceration-exacerbating effect in immunised than in normal animals. On day 7 the mean area of ulceration in immunised rabbits were 3 times greater in treated eyes. 0.01% clobetasone butyrate treatment had less effect on immunised rabbits; 0.001% had no effect. It is concluded that the immunised rabbit provides a useful experimental model for studying the relationship between concentration of topical anti-inflammatory agents and enhancement of herpetic ulceration. ...
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There exists a huge gap between protocols issued by scientific bodies and evidence derived by system biology studies on the multifactorial origin of threatened preterm delivery and their different associations with neonatal outcome. The objective of this prospective study was the analysis obstetrical and neonatal outcome in a cohort of pregnant patients treated for the risk of preterm delivery according to maternal and fetal assessment determined by amniotic fluid samples. Methods. Threatened preterm delivery and premature rupture of membranes between 24 + 1 and 32 + 6 weeks of gestation were treated by prolonged tocolytic regimens and if necessary by antibiotics for maternal infections when intra-amniotic inflammation (IAI) was excluded on the basis of negative white blood cell count in the amniotic fluid, or opposite, by delivery after a course of betamethasone and 48 hours maintenance tocolysis. Twenty-three cases were compared with 22 historical controls treated by the same teams according ...
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  • Dave, It sounds like it could be either betamethasone, or dexamethasone. (healingwell.com)
  • I don't know too much about betamethasone, but dexamethasone is used very often in the veterinary world. (healingwell.com)
  • The GDG noted that there is no conclusive evidence on the comparative efficacy of dexamethasone and betamethasone that would support a recommendation of one over the other. (who.int)
  • The group acknowledged that dexamethasone has an advantage over betamethasone in terms of lower cost and wider availability, and it is currently listed for use in pregnant women on the WHO Essential Medicine List and in WHO's Managing complications in pregnancy and childbirth: a guide for midwives and doctors . (who.int)
  • Four doses of dexamethasone 6 mg IM 12 hours apart or two doses of betamethasone 12 mg IM 24 hours apart were the preferred choice in most of the studies. (who.int)
  • The panel felt there might be important differences in pharmacological properties of dexamethasone and betamethasone dosage regimens and therefore considered this as a research priority. (who.int)
  • Betamethasone and dexchlorpheniramine maleate were determined separately in bulk active compound and pharmaceutical dosage forms by HPLC in C18 column [ 10 - 13 ]. (hindawi.com)
  • This is not a list of all drugs or health problems that interact with betamethasone oral solution. (drugs.com)
  • Study groups were as follows: TRH or betamethasone alone (between 24 and 27th days of gestation), TRH + betamethasone or betamethasone + TRH (second dose of drugs were added in the last 2 days), and the control. (biomedsearch.com)
  • Methods During 2 years of follow-up in the CIMESTRA trial, 160 patients received intra-articular betamethasone in up to four swollen joints/visit in combination with disease-modifying antirheumatic drugs. (bmj.com)
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  • The initial dosage of CELESTONE Syrup (betamethasone) may vary from 0.6 mg to 7.2 mg per day depending on the specific disease entity being treated. (rxlist.com)
  • Because betamethasone and dexchlorpheniramine produce their pharmacologic effects through different mechanisms, they can be used in combination in different dosage forms like tablets, oral solutions, or syrup to enhance the resulting therapeutic efficacy. (hindawi.com)
  • The described method can be successfully applied for determination of betamethasone concentrations in GCF obtained from patients with chronic periodontitis after local treatment with BDP cream 0.5 mg g -1 . (degruyter.com)
  • Betamethasone has an anti-inflammatory effect and is used to decrease inflammation in various different diseases and conditions. (netdoctor.co.uk)
  • Betamethasone is a synthetic glucocorticoid possessing anti-inflammatory [ 1 ] and antiallergic properties [ 2 ]. (hindawi.com)
  • I forget the name of the drug he gave me (an anti-inflammatory that might be called Betamethasone),is this normal? (healingwell.com)
  • The present study involves the identification of the thermal degradation products of these esters and evaluation of the kinetics of thermal degradation of betamethasone esters in phosphate buffer, organic solvents, and cream and gel formulations using a validated HPLC method. (ijpsonline.com)
  • Betamethasone is injected into a muscle, joint, or lesion, or given as a shallow injection just beneath the skin. (wellspan.org)
  • Call your doctor for instructions if you miss an appointment for your betamethasone injection. (wellspan.org)
  • Betamethasone decreases inflammation by acting within cells to prevent the release of certain chemicals that are important in the immune system. (netdoctor.co.uk)
  • Betamethasone can also be injected directly into inflamed soft tissue, for example in tennis elbow, to decrease inflammation in that particular area. (netdoctor.co.uk)
  • Topical betamethasone appears to interfere with the formation of natural substances within the body that are directly responsible for the process of inflammation, which produces swelling, redness, and itching. (wholehealthmd.com)
  • Betamethasone is used to treat many different inflammatory conditions such as allergic reactions, ulcerative colitis, arthritis, lupus, multiple sclerosis, inflammation of the joints or tendons, and problems caused by low adrenal gland hormone levels. (wellspan.org)
  • Betamethasone treats inflammation caused by multiple different disease states. (rxwiki.com)
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  • Antenatal Betamethasone for Women at Risk for Late Preterm Delivery. (nih.gov)
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  • Betamethasone is also used to stimulate fetal lung maturation (to prevent IRDS), and to decrease the incidence and mortality from intracranial hemorrhage in premature infants. (wikipedia.org)
  • Effects of betamethasone and thyroid releasing hormone on fetal lung maturation: an experimental and morphometric study. (biomedsearch.com)
  • OBJECTIVE: To determine the effects of betamethasone and thyroid releasing hormone (TRH) on morphologic fetal rabbit lung maturation when administered separately and in combination. (biomedsearch.com)
  • The association between prenatal betamethasone therapy and resolution of hydrops may be related to a different mechanism other than improvement of lung maturation. (biomedsearch.com)
  • Glucocorticoids, for instance, betamethasone, produce critical and varied metabolic effects, and change the host resistant response to distinctive helps. (medicinesmexico.com)
  • Betamethasone/dexchlorpheniramine (trade names Betadexin, Celestamine) is a drug containing betamethasone and dexchlorpheniramine maleate to treat allergic conditions. (wikipedia.org)
  • Betamethasone and dexchlorpheniramine maleate were simultaneously determined by UV-Vis spectrometry [ 14 ] and high-performance thin-layer chromatography [ 15 ]. (hindawi.com)
  • In this study, the blood results of 75 pregnant women under threat of preterm delivery (week of gestation 23+0 to 34+6), treated with Betamethasone will be analysed. (clinicaltrials.gov)
  • In a sheep model of fetal programming resulting from exposure at day 80 of gestation to Betamethasone (Beta-exposed), adult sheep at 6 to 9 months or 1.8 years of age have elevated mean arterial pressure (MAP) and attenuated spontaneous baroreflex sensitivity (sBRS) for control of heart rate compared to age-matched controls associated with imbalances in angiotensin (Ang) II vs Ang-(1-7) tone. (ahajournals.org)
  • Betamethasone, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity. (nih.gov)
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  • 2 Betamethasone has been used to improve lung function in premature infants, but recent longitudinal studies have shown that prenatal exposure to Betamethasone caused an elevation in blood pressure in preterm children at 14 years of age. (ahajournals.org)
  • 4 , 5 Investigating the mechanism of the vascular changes and the blood pressure elevation associated with prenatal exposure to Betamethasone is of clinical importance to better-diagnose and possibly protect these children from the consequences of prenatal Betamethasone exposure. (ahajournals.org)
  • If you are using betamethasone on a child's diaper area, do not use tight-fitting diapers or plastic pants. (medlineplus.gov)
  • Betamethasone foam may catch fire. (medlineplus.gov)
  • Stay away from open fire, flames, and do not smoke while you are applying betamethasone foam, and for a short time afterward. (medlineplus.gov)
  • To use betamethasone topical foam , spray some of the foam onto a plate or other cool surface. (cigna.com)
  • It is the aim of this study to detect the effect of Betamethasone on the maternal inflammatory parameters C-reactive protein (CRP) and leukocytes of a pregnant woman under threat of preterm delivery, for example because of a cervical infection. (clinicaltrials.gov)
  • Does Betamethasone Reduce Neonatal Complications for Women at Risk of Late Preterm Delivery? (empr.com)
  • HealthDay News - For women at risk for late preterm delivery, betamethasone administration reduces the rate of neonatal respiratory complications, according to a study published online Feb. 4 in the New England Journal of Medicine . (empr.com)
  • Administration of betamethasone to women at risk for late preterm delivery significantly reduced the rate of neonatal respiratory complications," the authors write. (empr.com)
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