Betamethasone
Betamethasone Valerate
Glucocorticoids
Sheep
Phimosis
Prenatal Exposure Delayed Effects
Ointments
Pregnancy
Administration, Topical
Clobetasol
Respiratory Distress Syndrome, Newborn
Delay of preterm delivery in sheep by omega-3 long-chain polyunsaturates. (1/339)
A positive correlation has been shown between dietary intake of long-chain omega-3 fatty acids in late pregnancy and gestation length in pregnant women and experimental animals. To determine whether omega-3 fatty acids have an effect on preterm labor in sheep, a fish oil concentrate emulsion was continuously infused to six pregnant ewes from 124 days gestational age. At 125 days, betamethasone was administered to the fetus to produce preterm labor. Both the onset of labor and the time of delivery were delayed by the fish oil emulsion. Two of the omega-3-infused ewes reverted from contractions to nonlabor, an effect never previously observed for experimental glucocorticoid-induced preterm labor in sheep. Maternal plasma estradiol and maternal and fetal prostaglandin E2 rose in control ewes but not in those infused with omega-3 fatty acid. The ability of omega-3 fatty acids to delay premature delivery in sheep indicates their possible use as tocolytics in humans. Premature labor is the major cause of neonatal death and long-term disability, and these studies present information that may lead to a novel therapeutic regimen for the prevention of preterm delivery in human pregnancy. (+info)Secondary glioblastoma remarkably reduced by steroid administration after anaplastic transformation from gliomatosis cerebri--case report. (2/339)
A 45-year-old female presented with gliomatosis cerebri manifesting as hemiballismus-like involuntary movement in the arm, motor weakness in the leg, and hypesthesia in her left side. Computed tomography showed only diffuse swelling of the right cerebral hemisphere, but T2-weighted magnetic resonance imaging revealed a diffuse lesion spreading from the right thalamus to the temporal, parietal, and occipital lobes on the same side. No abnormal enhancement was recognized. Cerebral angiography showed no specific finding. A right occipital lobectomy was performed to confirm the diagnosis of gliomatosis cerebri. Anaplastic transformation was recognized 5 months later. The disease did not resolve with radiation or interferon administration, but steroid therapy achieved remarkably effective tumor regression. The patient died due to pneumonia. Autopsy showed the features of diffuse glioblastoma. Steroid therapy may be an effective treatment for gliomatosis cerebri before the terminal stage. (+info)Betamethasone-mediated vascular dysfunction and changes in hematological profile in the ovine fetus. (3/339)
Glucocorticoid administration to fetal sheep induces a sustained systemic blood pressure rise and an associated increase in femoral vascular resistance. We utilized a small vessel myograph to compare isometric vascular responses of small femoral arterial branches from fetal sheep infused intravenously with either betamethasone or vehicle in vivo from 128 days gestation. Changes in hematological parameters were also determined. Betamethasone was infused for 48 h to produce fetal plasma betamethasone concentrations similar to those observed in human fetuses after maternal treatment with betamethasone to accelerate fetal lung maturation. When compared with vessels removed from vehicle-infused fetuses, vessels obtained from betamethasone-treated fetuses exhibited 1) enhanced sensitivity to depolarizing potassium solutions; 2) no differences in response to the thromboxane mimetic U-46619 or norepinephrine; and 3) differential responses to vasodilators, enhanced sensitivity to ACh, but decreased response to bradykinin and forskolin. In addition, erythrocyte and leukocyte counts were increased in betamethasone-infused fetuses. These observations indicate that multiple mechanisms operate to increase fetal vascular resistance during antenatal betamethasone exposure. (+info)Concentration of steroids in bovine peripheral plasma during the oestrous cycle and the effect of betamethasone treatment. (4/339)
Testosterone, oestradiol and progesterone were measured in peripheral plasma during the oestrous cycle of 6 heifers. Oestradiol and progesterone results confirmed earlier reports. Concentration of testosterone on the day of oestrus was 40+/-3 pg/ml (mean+/-S.E.M.), and two peaks were detected during the cycle, one 7 days before oestrus (1809+/-603 pg/ml) and the other (78+/- 7 pg/ml) on the day before the onset of oestrus. The concentration of progesterone declined in most cases 1 day after the maximum concentration of testosterone. Betamethasone treatment in 5 heifers extended luteal function by an average of 10 days: plasma androstenedione and oestradiol concentrations were unaltered; cortisol values were depressed for at least 16 days after treatment; testosterone concentrations were lowered by 13+/-2-4% during treatment, and except in one heifer the peak on Day -7 was abolished. (+info)Functional capacity of fetal zone cells of the baboon fetal adrenal gland: a major source of alpha-inhibin. (5/339)
We have shown that ACTH receptor mRNA expression and steroidogenesis were increased in the transitional zone and decreased in the fetal zone of the baboon fetal adrenal in the second half of gestation. Thus, we proposed that there is a divergence in ACTH receptor-mediated zone-specific steroidogenesis within the fetal adrenal during mid to late gestation. We have also demonstrated that fetal serum alpha-inhibin levels decline with advancing development. It is possible, therefore, that the alpha subunit of inhibin provides a good marker of fetal zone cellular function and that the changes in circulating fetal alpha-inhibin with advancing pregnancy reflect ontogenetic changes in fetal adrenal cortical zone-specific cell function. However, it remains to be determined whether the fetal adrenal is a major source of circulating alpha-inhibin in the fetus and whether alpha-inhibin is expressed in the fetal, definitive, and/or transitional zones. Therefore, the current study compared fetal serum alpha-inhibin levels with immunocytochemical localization of alpha-inhibin in baboon fetal adrenals obtained on Days 60 (early), 100 (mid), and 165 or 182 (late) of gestation (term averages Day 184) from animals untreated or treated with betamethasone, which we previously demonstrated suppressed fetal pituitary ACTH and adrenal weight. Fetal serum alpha-inhibin levels (mean +/- SE) were greater (p < 0.05) at mid (5863 +/- 730 microliter eq/ml) than at late (3246 +/- 379) gestation and were reduced (p < 0. 05) by betamethasone. The inhibin alpha subunit was expressed in abundant quantities in the fetal adrenal cortex, but not in medulla, throughout gestation. At mid and late gestation, alpha-inhibin was expressed throughout the fetal adrenal cortex but most intensely in the innermost area of fetal zone cells. By late gestation, the fetal adrenal exhibited a gradient of alpha-inhibin expression. Thus, the outermost definitive zone cells were devoid of alpha-inhibin, the transitional zone exhibited a relatively low alpha-inhibin content, and fetal zone cells continued to exhibit extensive expression of alpha-inhibin. Betamethasone diminished the intensity of alpha-inhibin expression throughout the fetal adrenal cortex. These results indicate that the fetal adrenal fetal zone is a significant source of circulating alpha-inhibin in the baboon fetus and that alpha-inhibin provides a good marker to study the developmental regulation of fetal zone-specific adrenocortical function. (+info)Spontaneous labour at term is associated with fetal monocyte activation. (6/339)
The aetiology of both term and preterm labour remains incompletely understood. Maternal infectious diseases as well as intra-uterine infections were shown to be a well established cause of uncontrollable preterm delivery, indicating that inflammatory reactions, regulated by maternal immunecompetent cells, are implicated in labour-promoting mechanisms. To investigate the possibility that the activation of the fetal immune system may be involved in labour induction, we examined cytokine production patterns of different cord blood cell populations obtained from neonates after spontaneous onset of normal term labour and vaginal delivery (n = 25), vaginal delivery but induced term labour (n = 17), and preterm delivery because of uncontrollable labour (n = 27, 20 patients received corticoid treatment for fetal lung maturation), in comparison with cells obtained from neonates after elective term caesarean delivery in the absence of labour (n = 15). Our results demonstrate that spontaneous term labour, but not induced term labour, was associated with significantly increased IL-6 production by myelomonocytic cell populations. Preterm delivery due to uncontrollable labour with resistance to tocolysis was not associated with increased IL-6 production by fetal myelomonocytic cells. Two-colour flow cytometry combined with intracellular cytokine staining was used to identify fetal monocytes as sources of labour-associated IL-6 release at term. We did not find any activation of cord blood T cells in association with spontaneous term or uncontrollable preterm labour. Therefore, fetal T cell responses may not cause monocyte activation. Our results suggest that increased release of IL-6 from fetal monocytes is involved in mechanisms promoting normal term, but not preterm labour, and that mechanisms inducing term and preterm labour are completely different. (+info)Developmental expression of and effect of betamethasone on the messenger ribonucleic acid levels for peptide growth factors in the baboon fetal adrenal gland. (7/339)
In the present study, we determined whether expression of the messenger ribonucleic acids (mRNAs) for insulin-like growth factor-II (IGF-II), and its principal IGF type-1 receptor and IGF-binding protein-2 (IGFBP-2), as well as basic fibroblast growth factor (bFGF), was developmentally regulated in the baboon fetal adrenal gland. In the second phase of this study, fetal pituitary ACTH was suppressed by the administration of betamethasone to determine the possible effect on the mRNA levels for those factors, i.e. IGF-II and IGFBP-2, shown to be expressed at high levels in the adrenal late in fetal development. Adrenals were obtained from fetuses delivered via Cesarean section on days 60 (early), 100 (mid), and 165 (late) of gestation (term=184 days) from untreated baboons and on day 165 from baboons in which betamethasone was administered to the fetus, or to fetus and mother, every other day between days 150 and 164 of gestation. Although the mRNA levels of IGF-II in the fetal adrenal were similar at early, mid and late gestation, IGF type-1 receptor mRNA levels were approximately 2- to 3-fold greater (P<0.01) at mid than at early or late gestation. In contrast, there was an increase (P<0.001) in fetal adrenal IGFBP-2 and bFGF mRNA levels in late gestation. Although fetal adrenal weights and width of the zone of definitive/transitional cells exhibiting immunocytochemical staining for Delta(5)-3beta-hydroxysteroid dehydrogenase (3beta-HSD) were markedly suppressed (P<0.01) by the administration of betamethasone, IGF-II and IGFBP-2 mRNA expression was not decreased. In summary, very different patterns of mRNA levels for IGF-II, IGF type-1 receptor, IGFBP-2 and bFGF were exhibited in the developing baboon fetal adrenal gland, which may reflect functionally important differences in their respective cellular localization within the cortex, as well as a divergence in the functional development of the fetal, transitional and definitive zones of the baboon fetal adrenal cortex. (+info)Antenatal glucocorticoid treatment and cystic periventricular leukomalacia in very premature infants. (8/339)
BACKGROUND: Antenatal glucocorticoid therapy decreases the incidence of several complications among very premature infants. However, its effect on the occurrence of cystic periventricular leukomalacia, a major cause of cerebral palsy, remains unknown. METHODS: We retrospectively analyzed a cohort of 883 live-born infants, with gestational ages ranging from 24 to 31 weeks, who were born between January 1993 and December 1996 at three perinatal centers in the Paris area. The mothers of 361 infants had received betamethasone before delivery, the mothers of 165 infants had received dexamethasone before delivery, and the mothers of 357 infants did not receive glucocorticoids. We compared the rates of cystic periventricular leukomalacia among the three groups of infants in bivariate and multivariate analyses after adjustment for confounding factors. RESULTS: The rate of cystic periventricular leukomalacia was 4.4 percent among the infants whose mothers had received betamethasone, 11.0 percent among the infants whose mothers had received dexamethasone, and 8.4 percent among the infants whose mothers had not received a glucocorticoid. After adjustment for gestational age, the mode of delivery, and the presence or absence of chorioamnionitis, prolonged interval between the rupture of membranes and delivery (>24 hours), preeclampsia, and the use of tocolytic drugs, antenatal exposure to betamethasone was associated with a lower risk of cystic periventricular leukomalacia than was either the absence of glucocorticoid therapy (adjusted odds ratio, 0.5; 95 percent confidence interval, 0.2 to 0.9) or exposure to dexamethasone (adjusted odds ratio, 0.3; 95 percent confidence interval, 0.1 to 0.7). The adjusted odds ratio for the group of infants whose mothers had received dexamethasone as compared with the group of infants whose mothers had not received a glucocorticoid was 1.5 (95 percent confidence interval, 0.8 to 2.9). CONCLUSIONS: Antenatal exposure to betamethasone but not dexamethasone is associated with a decreased risk of cystic periventricular leukomalacia among very premature infants. (+info)Betamethasone is a type of corticosteroid medication that is used to treat various medical conditions. It works by reducing inflammation and suppressing the activity of the immune system. Betamethasone is available in several forms, including creams, ointments, lotions, gels, solutions, tablets, and injectable preparations.
The medical definition of betamethasone is:
A synthetic corticosteroid with anti-inflammatory, immunosuppressive, and vasoconstrictive properties. It is used to treat a variety of conditions such as skin disorders, allergies, asthma, arthritis, and autoimmune diseases. Betamethasone is available in various formulations including topical (creams, ointments, lotions, gels), oral (tablets), and injectable preparations. It acts by binding to specific receptors in cells, which leads to the inhibition of the production of inflammatory mediators and the suppression of immune responses.
It is important to note that betamethasone should be used under the guidance of a healthcare professional, as it can have significant side effects if not used properly.
Betamethasone valerate is a synthetic corticosteroid drug, which is a derivative of betamethasone. It is used as a topical preparation for the treatment of various skin conditions such as eczema, psoriasis, and dermatitis. The valerate ester of betamethasone provides a sustained release of the active steroid, allowing for less frequent application and improved penetration into the skin.
Betamethasone valerate works by reducing inflammation, suppressing the immune system, and relieving itching and redness in the affected area. It is available in various forms, including creams, ointments, and lotions, and should be used under the direction of a healthcare professional to ensure proper use and minimize potential side effects.
Like other corticosteroids, betamethasone valerate can cause thinning of the skin, increased hair growth, and acne with prolonged or excessive use. It is important to follow the recommended dosage and duration of treatment to avoid these side effects.
Glucocorticoids are a class of steroid hormones that are naturally produced in the adrenal gland, or can be synthetically manufactured. They play an essential role in the metabolism of carbohydrates, proteins, and fats, and have significant anti-inflammatory effects. Glucocorticoids suppress immune responses and inflammation by inhibiting the release of inflammatory mediators from various cells, such as mast cells, eosinophils, and lymphocytes. They are frequently used in medical treatment for a wide range of conditions, including allergies, asthma, rheumatoid arthritis, dermatological disorders, and certain cancers. Prolonged use or high doses of glucocorticoids can lead to several side effects, such as weight gain, mood changes, osteoporosis, and increased susceptibility to infections.
"Fetal organ maturity" refers to the stage of development and functional competency of the various organs in a fetus. It is the point at which an organ has developed enough to be able to perform its intended physiological functions effectively and sustainably. This maturity is determined by a combination of factors including structural development, cellular differentiation, and biochemical functionality.
Fetal organ maturity is a critical aspect of fetal development, as it directly impacts the newborn's ability to survive and thrive outside the womb. The level of maturity varies among different organs, with some becoming mature earlier in gestation while others continue to develop and mature until birth or even after.
Assessment of fetal organ maturity is often used in clinical settings to determine the optimal time for delivery, particularly in cases where there are risks associated with premature birth. This assessment typically involves a combination of imaging studies, such as ultrasound and MRI, as well as laboratory tests and physical examinations.
I apologize, but "sheep" is not a term that has a medical definition. It is a common animal with the scientific name Ovis aries. If you have any medical or health-related questions, I would be happy to try and help answer those for you.
Phimosis is a medical condition where the foreskin of the penis, which is the retractable sheath of skin that covers the head or glans of the penis, cannot be pulled back (retracted) over the glans. This condition is normal in uncircumcised infant boys and toddlers, but most boys can retract their foreskins by the time they reach puberty.
In some cases, phimosis may cause no symptoms or problems, while in others it may lead to issues such as discomfort, pain, especially during sexual activity, infection, inflammation, and difficulty urinating. Phimosis can be caused by various factors, including infections, skin conditions, scarring from previous injuries or surgeries, or forceful attempts to retract the foreskin.
Treatment for phimosis depends on the underlying cause and severity of the condition. In some cases, gentle manual stretching exercises may be recommended to gradually increase the foreskin's ability to retract. In other cases, topical creams or medications may be prescribed to reduce inflammation or fight infections. If these treatments are not effective, or if phimosis is causing significant discomfort or complications, circumcision (surgical removal of the foreskin) may be considered as a last resort.
"Prenatal exposure delayed effects" refer to the adverse health outcomes or symptoms that become apparent in an individual during their development or later in life, which are caused by exposure to certain environmental factors or substances while they were still in the womb. These effects may not be immediately observable at birth and can take weeks, months, years, or even decades to manifest. They can result from maternal exposure to various agents such as infectious diseases, medications, illicit drugs, tobacco smoke, alcohol, or environmental pollutants during pregnancy. The delayed effects can impact multiple organ systems and may include physical, cognitive, behavioral, and developmental abnormalities. It is important to note that the risk and severity of these effects can depend on several factors, including the timing, duration, and intensity of the exposure, as well as the individual's genetic susceptibility.
An ointment is a semi-solid preparation, typically composed of a mixture of medicinal substance with a base, which is usually greasy or oily. The purpose of the base is to act as a vehicle for the active ingredient and allow it to be applied smoothly and evenly to the skin or mucous membranes.
Ointments are commonly used in dermatology to treat various skin conditions such as eczema, psoriasis, rashes, burns, and wounds. They can also be used to deliver medication for localized pain relief, muscle relaxation, and anti-inflammatory or antibiotic effects.
The base of an ointment may consist of various ingredients, including petrolatum, lanolin, mineral oil, beeswax, or a combination of these. The choice of the base depends on the desired properties such as consistency, spreadability, and stability, as well as the intended route of administration and the specific therapeutic goals.
Anti-inflammatory agents are a class of drugs or substances that reduce inflammation in the body. They work by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which are released during an immune response and contribute to symptoms like pain, swelling, redness, and warmth.
There are two main types of anti-inflammatory agents: steroidal and nonsteroidal. Steroidal anti-inflammatory drugs (SAIDs) include corticosteroids, which mimic the effects of hormones produced by the adrenal gland. Nonsteroidal anti-inflammatory drugs (NSAIDs) are a larger group that includes both prescription and over-the-counter medications, such as aspirin, ibuprofen, naproxen, and celecoxib.
While both types of anti-inflammatory agents can be effective in reducing inflammation and relieving symptoms, they differ in their mechanisms of action, side effects, and potential risks. Long-term use of NSAIDs, for example, can increase the risk of gastrointestinal bleeding, kidney damage, and cardiovascular events. Corticosteroids can have significant side effects as well, particularly with long-term use, including weight gain, mood changes, and increased susceptibility to infections.
It's important to use anti-inflammatory agents only as directed by a healthcare provider, and to be aware of potential risks and interactions with other medications or health conditions.
Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.
Topical administration refers to a route of administering a medication or treatment directly to a specific area of the body, such as the skin, mucous membranes, or eyes. This method allows the drug to be applied directly to the site where it is needed, which can increase its effectiveness and reduce potential side effects compared to systemic administration (taking the medication by mouth or injecting it into a vein or muscle).
Topical medications come in various forms, including creams, ointments, gels, lotions, solutions, sprays, and patches. They may be used to treat localized conditions such as skin infections, rashes, inflammation, or pain, or to deliver medication to the eyes or mucous membranes for local or systemic effects.
When applying topical medications, it is important to follow the instructions carefully to ensure proper absorption and avoid irritation or other adverse reactions. This may include cleaning the area before application, covering the treated area with a dressing, or avoiding exposure to sunlight or water after application, depending on the specific medication and its intended use.
Clobetasol is a topical corticosteroid medication that is used to reduce inflammation and relieve itching, redness, and swelling associated with various skin conditions. It works by suppressing the immune system's response to reduce inflammation. Clobetasol is available in several forms, including creams, ointments, emulsions, and foams, and is usually applied to the affected area once or twice a day.
It is important to use clobetasol only as directed by a healthcare provider, as prolonged or excessive use can lead to thinning of the skin, increased susceptibility to infections, and other side effects. Additionally, it should not be used on large areas of the body or for extended periods without medical supervision.
Respiratory Distress Syndrome (RDS), Newborn is a common lung disorder in premature infants. It occurs when the lungs lack a substance called surfactant, which helps keep the tiny air sacs in the lungs open. This results in difficulty breathing and oxygenation, causing symptoms such as rapid, shallow breathing, grunting noises, flaring of the nostrils, and retractions (the skin between the ribs pulls in with each breath). RDS is more common in infants born before 34 weeks of gestation and is treated with surfactant replacement therapy, oxygen support, and mechanical ventilation if necessary. In severe cases, it can lead to complications such as bronchopulmonary dysplasia or even death.
Betamethasone
Betamethasone phosphate
Betamethasone dipropionate
Betamethasone valerate
Betamethasone acetate
Lotion
Bruise
Medina Spirit
Bob Baffert
Calcipotriol
2021 Kentucky Derby
Antenatal steroid
Diprobase
Thermophobia
Corticosteroid
Schering-Plough
Alejandro Marque
Noraldo Palacios
Gestational pemphigoid
Anne Anderson (researcher)
Vernal keratoconjunctivitis
Actinic prurigo
Mouthwash
Calcitriol
Ludger Beerbaum
Emanuel Molina
Gamine (horse)
Fluocortolone
Halometasone
List of drugs known for off-label use
Betamethasone - Wikipedia
Betamethasone, Topical use while Breastfeeding | Drugs.com
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Betamethasone Dipropionate: Medgend
Valerate8
- Many betamethasone-based pharmaceuticals include the steroid as the valerate ester. (wikipedia.org)
- Betamethasone is available in a number of compound forms: betamethasone dipropionate (branded as Diprosone, Diprolene, Celestamine, Procort (in Pakistan), and others), betamethasone sodium phosphate (branded as Bentelan in Italy) and betamethasone valerate (branded as Audavate, Betnovate, Celestone, Fucibet, and others). (wikipedia.org)
- The phrase "betamethasone valerate is potentially persistent" is thus chosen. (janusinfo.se)
- Risk of environmental impact of betamethasone valerate cannot be excluded, since there is not sufficient ecotoxicity data available. (janusinfo.se)
- As soln (containing betamethasone dipropionate 0.05% w/w and salicylic acid 2% w/w) or oint (containing betamethasone dipropionate 0.05% w/w and salicylic acid 3% w/w or betamethasone valerate 0.1% w/w and salicylic acid 3% w/w): Apply to the affected area 1-2 times daily for 2 wk. (mims.com)
- Although the majority of study patients were Caucasian and the study protocol did not allow analysis of the data to determine whether betaderm betamethasone valerate cost these two conditions might be related, the current report was unable to substantiate this potential explanation (n=3). (voltaire-a-ferney.org)
- Clobetasol propionate, diflucortolone valerate, and dexamethasone nasal sprays were used in the majority of previously reported cases of corticosteroid abuse, whereas this is the first case of CS in an infant as a result of the use of betamethasone cream, also known as betnesol, which is frequently used by mothers in developing countries as a treatment for rashes. (qxmd.com)
- We also perform custom synthesis and purification of Betamethasone Valerate Impurity H from mg to gm scale. (blogspot.com)
0.056
- A cream with 0.05% betamethasone appears effective in treating phimosis in boys, and often averts the need for circumcision. (wikipedia.org)
- Betamethasone Dipropionate Lotion, USP 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. (nih.gov)
- In a randomized, double-bind trial, lanolin was compared to an all-purpose nipple ointment containing betamethasone 0.05%, mupirocin 1%, and miconazole 2% for painful nipples while nursing in the first 2 weeks postpartum. (drugs.com)
- Can betamethasone dipropionate cream 0.05% shrink testicles? (healthtap.com)
- For betamethasone dipropionate cream, usp 0.05% (almus brand): if applied to glans of penis 2-3 times/day for 7-9 days can this result in shrinkage of testicles, fertility issues, impact sexual health or any other negative issues short/long term? (healthtap.com)
- Apply Betamethasone cream with 0.05% Betamethasone on the penis for treating phimosis in boys, eventually resulting in averting the need for circumcision. (pipelinepharma.com)
Topical15
- topical betamethasone should be avoided on the nipple. (drugs.com)
- She was also taking cetirizine 10 mg daily and topical betamethasone 0.1% twice daily to the lesions. (drugs.com)
- Betamethasone topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). (epnet.com)
- To use betamethasone topical, apply a small amount of ointment, cream, solution, gel, or lotion to cover the affected area of skin with a thin even film and rub it in gently. (epnet.com)
- Do not let betamethasone topical get into your eyes or mouth and do not swallow it. (epnet.com)
- tell your doctor and pharmacist if you are allergic to betamethasone, any other medications, or any of the ingredients in betamethasone topical products. (epnet.com)
- If you become pregnant while using betamethasone topical, call your doctor immediately. (epnet.com)
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using betamethasone topical. (epnet.com)
- Children who use betamethasone topical may have an increased risk of side effects including slowed growth and delayed weight gain. (epnet.com)
- Below is the selection of side effect reports (a.k.a. adverse event reports) related to Betamethasone (Betamethasone Topical) where reactions include premature delivery. (druglib.com)
- Betamethasone 0.1 topical ointment Betametasona crema precio farmacia del ahorro 1/100 of a tablet. (highlandpix.co.uk)
- The topical cream relieves skin irritations like itching and flaking from eczema, local psoriasis, in combination with calcipotriol/betamethasone dipropionate. (pipelinepharma.com)
- Betamethasone topical spray is employed to treat adults with delicate to moderate plaque skin disorder. (veeprho.com)
- Preparations containing calcipotriol combined with betamethasone dipropionate (in the forms of ointment, gel, and foam) are available for the topical treatment of psoriasis. (encyclopedia.pub)
- Betamethasone dipropionate topical is for inflammatory dermatoses responsive to steroids. (medscape.com)
Salicylic acid4
- It is used as a treatment for local psoriasis, as betamethasone dipropionate and salicylic acid, or as the combination calcipotriol/betamethasone dipropionate. (wikipedia.org)
- Disclaimer: This information is independently developed by MIMS based on Betamethasone + Salicylic acid from various references and is provided for your reference only. (mims.com)
- Whereas In India, the price of Betamethasone dipropionate 0.64mg and salicylic acid 30mg per gram is $0.80. (pipelinepharma.com)
- Sci-Hub, Development and Validation of a Stability-Indicating HPLC Method for Simultaneous Determination of Salicylic Acid, Betamethasone Dipropionate and Their Related Compounds in Diprosalic Lotion®, 10.1016/J.jpba.2009.05.015. (veeprho.com)
Acetate5
- Betamethasone sodium phosphate mixed with betamethasone acetate is available in the United States as Celestone Soluspan. (wikipedia.org)
- Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension is a sterile aqueous suspension containing 3 mg per milliliter betamethasone (equivalent to 3.95 mg betamethasone sodium phosphate USP) and 3 mg per milliliter betamethasone acetate. (nih.gov)
- The formula for betamethasone acetate is C 24 H 31 FO 6 and it has a molecular weight of 434.50. (nih.gov)
- Betamethasone acetate is a white to creamy white, odorless powder that sinters and resolidifies at about 165°C, and remelts at about 200°C-220°C with decomposition. (nih.gov)
- Betamethasone sodium phosphate, a soluble ester, provides prompt activity, while betamethasone acetate is only slightly soluble and affords sustained activity. (nih.gov)
Clotrimazole1
- In the United States and Canada, betamethasone is mixed with clotrimazole and sold as Lotrisone and Lotriderm. (wikipedia.org)
Corticosteroid3
- Betamethasone is a corticosteroid that is available as a pill, by injection, and as an ointment, cream, lotion, gel, or aerosol (spray) for the skin, and a foam for the scalp. (wikipedia.org)
- Betamethasone is a synthetic fluorinated corticosteroid. (mims.com)
- Betamethasone is a corticosteroid used for a number of diseases including rheumatic disorders, skin diseases, allergic conditions, Crohn's disease. (amitahc.com)
20231
- Calcipotriol/Betamethasone Dipropionate in Psoriasis" Encyclopedia , https://encyclopedia.pub/entry/17039 (accessed December 01, 2023). (encyclopedia.pub)
Prednisolone5
- Betamethasone, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity. (nih.gov)
- A derivative of prednisolone, betamethasone has a 16β-methyl group that enhances the anti-inflammatory action of the molecule and reduces the sodium- and water-retaining properties of the fluorine atom bound at carbon 9. (nih.gov)
- The most common class of steroids is glucocorticoids that comprise betamethasone, methylprednisolone, dexamethasone, and prednisolone. (hindawi.com)
- Comparative assessment of environmental risk when using the corticosteroids betamethasone, budesonide, hydrocortisone and prednisolone from a Swedish perspective. (janusinfo.se)
- Hydrocortisone and prednisolone have a lower environmental risk but are rarely medically interchangeable alternatives to betamethasone and budesonide. (janusinfo.se)
Drugs2
- Tocolytics ( drugs to stop preterm labor ) can be used to allow betamethasone to act fully. (brighthub.com)
- Normally, finding trusted manufacturers and supplies of specific drugs like Betamethasone can be a time-consuming challenge, but with Pipelinepharma's simple search engine and network of proven partners, the whole process becomes a lot easier. (pipelinepharma.com)
Dexamethasone1
- Besides using betamethasone for lung maturity, dexamethasone (another glucocorticoid) may also be used. (brighthub.com)
Baby's lungs1
- Also included for treatment by Betamethasone are allergic conditions such as asthma and angioedema, Crohn's disease, cancers such as leukemia, in fludrocortisone for adrenocortical insufficiency, and in preterm labor to speed up the development of baby's lungs. (pipelinepharma.com)
Betnovate Cream1
- Betnovate Cream (Betamethasone) is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). (safetymedpharmacy.com)
0.641
- Each gram contains 0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a vehicle of isopropyl alcohol and purified water slightly thickened with carbomer 974P. (nih.gov)
Psoriasis1
- Betamethasone is an important glucocorticoids (GCs), frequently used to cure allergies (such as asthma and angioedema), Crohn's disease, skin diseases (such as dermatitis and psoriasis), systemic lupus erythematosus, rheumatic disorders, and leukemia. (hindawi.com)
Lotion1
- Betamethasone comes in ointment, cream, lotion, gel, and aerosol (spray) in various strengths for use on the skin and as a foam to apply to the scalp. (epnet.com)
Sodium phosphate3
- Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids. (wikipedia.org)
- The formula for betamethasone sodium phosphate is C 22 H 28 FNa 2 0 8 P and it has a molecular weight of 516.40. (nih.gov)
- Betamethasone sodium phosphate is a white to practically white, odorless powder, and is hygroscopic. (nih.gov)
Systemic1
- In this instance, a severe medication interaction caused by systemic betamethasone cream buildup led to the creation of CS. (qxmd.com)
Search2
- All you need to do to get started is to make use of our integrated search engine and start looking for suppliers or manufacturers of Betamethasone to work with. (pipelinepharma.com)
- You can fine-tune your search results using various filters too, letting you search for Betamethasone from specific countries, for example. (pipelinepharma.com)
Doses1
- Using high doses of betamethasone over the long term may lead to adrenal suppression, which can cause hypertension, diabetes, osteoporosis, and other complications. (buyoverthecounteruk.net)
Steroid2
- Betamethasone is a steroid medication. (wikipedia.org)
- I got the steroid shot betamethasone since we suspect she may want to come early. (babycenter.com)
Glucocorticoid receptors2
- Present investigation deals to find potential agonist of glucocorticoid receptors after biotransformation of betamethasone dipropionate (1) and to carry out the molecular docking and ADME analyses. (hindawi.com)
- Betamethasone works by binding to intracellular glucocorticoid receptors. (pipelinepharma.com)
19582
- Betamethasone was patented in 1958, and approved for medical use in the United States in 1961. (wikipedia.org)
- Schering pharma first patented Betamethasone in 1958 for which approval was given in the United States in 1961. (pipelinepharma.com)
Impurity1
- It is associate impurity of Betamethasone. (veeprho.com)
Synthetic2
- The use of both betamethasone and budesonide poses an environmental risk, and exchange with synthetic glucocorticoids with a lower environmental risk is to be advocated in cases where it is possible from a clinical perspective. (janusinfo.se)
- Betamethasone dipropionate belongs to the group of synthetic fluorinated glucocorticoids that exhibit anti-inflammatory and immunosuppressive effects by binding to glucocorticoid cytosolic receptors and then translocating to the nucleus where they regulate the transcription of numerous genes responsible for the immune response. (encyclopedia.pub)
Foam2
Inflammatory2
- Pharmacodynamic studies showed the anti-inflammatory and immunoregulatory synergy of the combination of calcipotriol and betamethasone dipropionate with respect to the effects of these active substances administered individually [ 4 ] . (encyclopedia.pub)
- Calcipotriol affects keratinocyte differentiation, while betamethasone influences inflammatory processes and minimizes skin irritation (e.g., pruritus) after calcipotriol application [ 5 ] . (encyclopedia.pub)
Intramuscular1
- The animals in group B were given intramuscular betamethasone daily, those in group S were given saline injections daily, and those in group C were not submitted to any intervention. (bvsalud.org)
Fetal lung maturation2
- Betamethasone is also used to stimulate fetal lung maturation in order to prevent infant respiratory distress syndrome (IRDS) and to decrease the incidence and mortality from intracranial hemorrhage in premature infants. (wikipedia.org)
- When preterm labor occurs (between 24 and 34 weeks) and delivery is expected within seven days, betamethasone (BMS) may be given to accelerate fetal lung maturation and help prevent respiratory distress syndrome. (brighthub.com)
20181
- The use of betamethasone (sales data Sweden 2018) has been considered to result in high environmental risk. (janusinfo.se)
Placenta1
- However, because betamethasone crosses the placenta, which is required for its beneficial effects, it may also be associated with complications, such as hypoglycemia and leukocytosis in newborns exposed in utero. (wikipedia.org)
Dermatitis1
- Because of excessive betamethasone treatment in this child with diaper dermatitis, he acquired CS. (qxmd.com)
Dosage1
- The half-life of betamethasone is approximately 36 to 54 hours, but the elimination rate can vary depending on factors such as age, liver and kidney function, and dosage. (buyoverthecounteruk.net)
Drugstore1
- Why Buy Betamethasone from Universal Drugstore? (universaldrugstore.com)
Medication1
- Betamethasone belongs to the glucocorticoid class of medication. (wikipedia.org)
Price2
- Order Betamethasone at a discount price today! (universaldrugstore.com)
- Betamethasone Ointment Price. (voltaire-a-ferney.org)
Healthcare3
- Therefore, it is crucial to speak with a healthcare provider about the risks and benefits of drinking alcohol while taking betamethasone. (buyoverthecounteruk.net)
- It is important to follow your healthcare provider's instructions regarding alcohol consumption while taking betamethasone. (buyoverthecounteruk.net)
- It is best to consult with a healthcare provider for specific recommendations regarding alcohol consumption while taking betamethasone. (buyoverthecounteruk.net)