Beta lipotropin. Medical search

A 90-amino acid peptide derived from post-translational processing of pro-opiomelanocortin (POMC) in the PITUITARY GLAND and the HYPOTHALAMUS. It is the C-terminal fragment of POMC with lipid-mobilizing activities, such as LIPOLYSIS and steroidogenesis. Depending on the species and the tissue sites, beta-LPH may be further processed to yield active peptides including GAMMA-LIPOTROPIN; BETA-MSH; and ENDORPHINS.

One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.

The outer layer of the adrenal gland. It is derived from MESODERM and comprised of three zones (outer ZONA GLOMERULOSA, middle ZONA FASCICULATA, and inner ZONA RETICULARIS) with each producing various steroids preferentially, such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE. Adrenal cortex function is regulated by pituitary ADRENOCORTICOTROPIN.

Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

The wide middle zone of the adrenal cortex. This zone produces a series of enzymes that convert PREGNENOLONE to cortisol (HYDROCORTISONE) via 17-ALPHA-HYDROXYPROGESTERONE.

Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.

A melanocortin receptor subtype found primarily in the ADRENAL CORTEX. It shows specificity for ADRENOCORTICOTROPIC HORMONE.

A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN.

Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS OF HYPOTHALAMUS.

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Structurally, they include polypeptide, protein, and glycoprotein molecules.

Group of chemokines without adjacent cysteines that are chemoattractants for lymphocytes only.

Chemical substances that attract or repel cells. The concept denotes especially those factors released as a result of tissue injury, microbial invasion, or immunologic activity, that attract LEUKOCYTES; MACROPHAGES; or other cells to the site of infection or insult.

A cytokine produced by activated T-LYMPHOCYTES that stimulates the migration of CD4-POSITIVE LYMPHOCYTES and monocytes. It has been reported to suppress HIV replication.

White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.

A genus (and common name) in the AGAVACEAE family. It is known for SAPONINS in the root that are used in SOAPS.

The writing of history; the principles, theory, and history of historical writing; the product of historical writing. (Webster, 3d ed)

A class of plasmids that transfer antibiotic resistance from one bacterium to another by conjugation.

Heat and stain resistant, metabolically inactive bodies formed within the vegetative cells of bacteria of the genera Bacillus and Clostridium.

The capacity to conceive or to induce conception. It may refer to either the male or female.

A plasmid whose presence in the cell, either extrachromosomal or integrated into the BACTERIAL CHROMOSOME, determines the "sex" of the bacterium, host chromosome mobilization, transfer via conjugation (CONJUGATION, GENETIC) of genetic material, and the formation of SEX PILI.

The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed)

Antibodies produced by a single clone of cells.

The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.

Immunoglobulins produced in response to VIRAL ANTIGENS.

Organic or inorganic compounds that contain the -N3 group.

Immunoglobulins produced in a response to BACTERIAL ANTIGENS.

NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.

Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.

An imperfect fungus present on most agricultural seeds and often responsible for the spoilage of seeds in bulk storage. It is also used in the production of fermented food or drink, especially in Japan.

Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.

Differences of opinion or disagreements that may arise, for example, between health professionals and patients or their families, or against a political regime.

A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).

One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.

One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral nervous systems and in the adrenal medulla.

Vesicles derived from the GOLGI APPARATUS containing material to be released at the cell surface.

Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. It is sometimes used in conjunction with heat, moxibustion, acupressure, or electric stimulation.

The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.

Designated locations along nerves or organ meridians for inserting acupuncture needles.

Analgesia produced by the insertion of ACUPUNCTURE needles at certain ACUPUNCTURE POINTS on the body. This activates small myelinated nerve fibers in the muscle which transmit impulses to the spinal cord and then activate three centers - the spinal cord, midbrain and pituitary/hypothalamus - to produce analgesia.

Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.

Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands. (1/105)

The isolation of an untriakontapeptide from camel pituitary extracts has been described. Its structure has been determined and shown to be identical to the sequence of carboxyl-terminal 31 amino acids of ovine beta-lipotropin. The peptide possesses very low lipotropic activity but significant opiate activity. (+info)

Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin. (2/105)

The pituitary peptide beta-lipotropin displays essentially no opoid activity in a preparation of guinea pig ileum or in the opiate receptor binding assay. However, a fragment, beta-lipotropin-(61-91), with the enkephalin sequence (Tyr-Gly-Gly-Phe-Met) at its NH2-terminus, has typical opioid effects in these two assays. (+info)

beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. (3/105)

The hypophysial homomeric peptide beta-lipotropin (beta-LPH-[1-91]) has no morphinomomimetic activity in a bioassay (myenteric plexus-longitudinal muscle of the guinea pig's ileum) or binding assays with stereospecific opiate-receptors of rat brain synaptosome preparations. Incubating beta-LPH-[1-91] at neutral pH with the supernatant aqueous extracts of rat brain generates (fragments of beta-LPH with) morphinomimetic activity in the same assay systems. These results are related to the recently recognized structural relationships between beta-LPH, the newly isolated peptides met-enkephalin (beta-LPH-[61-65]) and alpha-endorphin (beta-LPH-[61-76]) and also to the biologically active fragments of analogs: beta-LPH-[61-64], beta-LPH-[61-65[-NH2, (Met(O)65)-BETA-LPH-[61-65], beta-LPH-[61-69], and beta-LPH-[61-69]. Enzymatic biogenesis of these morphinomimetic peptides would preclude localizing them as such in cellular or subcellular elements with currently available methodology. (+info)

Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. (4/105)

In the myenteric plexus-longitudinal muscle bioassay, beta-endorphin, i.e., beta-lipotropin (beta-LPH)-[61-91], has a potency of 450 with confidence limits of 281-966 when Met5-enkephalin is used as a reference standard with a potency of 100. The primary amide and the ethylamide of Met5-enkephalin have potencies statistically overlapping with that of beta-endorphin. The primary amide of alpha-endorphin has twice the potency of the free acid form of alpha-endorphin. An intact NH2-terminal tyrosine is not necessary for full intrinsic activity. The shortest fragment of beta-LPH with morphinomimetic activity is beta-LPH-[61-64]. (+info)

Altered processing of pro-orphanin FQ/nociceptin and pro-opiomelanocortin-derived peptides in the brains of mice expressing defective prohormone convertase 2. (5/105)

The bioactivity of neuropeptides can be regulated by a variety of post-translational modifications, including proteolytic processing. Here, gene-targeted mice producing defective prohormone convertase 2 (PC2) were used to examine the post-translational processing of two neuroendocrine prohormones, pro-opiomelanocortin (POMC) and pro-orphanin FQ (pOFQ)/nociceptin (N), in the brain. Reversed-phase HPLC and gel-exclusion chromatography were combined with specific radioimmunoassays to analyze the processing patterns of these two prohormones in the hypothalamus and the amygdala. In the case of POMC, the lack of PC2 activity completely prevented carboxy-shortening of beta-endorphins and greatly diminished conversion of beta-lipotropin to gamma-lipotropin and beta-endorphin. Although conversion of beta-lipotropin to beta-endorphin decreased, the lack of PC2 activity caused an increase in beta-lipotropin and beta-endorphin levels in the mutant animals, but no increases in POMC or biosynthetic intermediates were seen. The extent of OFQ/N production was significantly lower in PC2-deficient mice and there was an accumulation of relatively large amounts of pOFQ/N and biosynthetic intermediates. These results demonstrate that PC2 is directly involved in the biogenesis of two brain neuropeptides in vivo and suggest that the specific prohormone and cellular context influences neuropeptide processing by PCs. (+info)

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes. (6/105)

Two mammalian gene products, PC2 and PC3, have been proposed as candidate neuroendocrine-precursor processing enzymes based on the structural similarity of their catalytic domains to that of the yeast precursor-processing endoprotease Kex2. In this report we demonstrate that these two proteases can cleave proopiomelanocortin (POMC) in the secretory pathway of mammalian cells. Similarly to pituitary corticotrophs, PC3 expressed in processing-deficient BSC-40 cells cleaved native mouse POMC at the -Lys-Arg- sites flanking corticotropin. The -Lys-Arg- within beta-lipotropin was less efficiently cleaved to release beta-endorphin. Expression of PC2 together with PC3 resulted in efficient conversion of beta-lipotropin, as occurs in pituitary melanotrophs. Furthermore, coexpression of PC2 together with mouse POMC in bovine adrenomedullary chromaffin cells resulted in conversion of beta-lipotropin to gamma-lipotropin and beta-endorphin in the regulated secretory pathway. Finally, the processing selectivities of PC3 and PC2 expressed together in BSC-40 cells were determined by using a series of mutant mouse POMCs containing all possible pairs of basic residues at certain sites. The observed pattern of cleavage site selectivities mimicked that of the endogenous endoproteases of the insulinoma and bovine adrenomedullary chromaffin cells, suggesting that PC2 and PC3 may represent important core endoproteases in the catalysis of prohormone processing in many neuroendocrine cell types. (+info)

Effect of calcium ions on the processing of pro-opiomelanocortin by bovine intermediate lobe pro-opiomelanocortin-converting enzyme. (7/105)

The effect of Ca2+ on the extent and pattern of processing of pro-opiomelanocortin and an N-terminal fragment by a purified pituitary secretory vesicle, soluble aspartic endoprotease, was studied. Ca2+ stimulated the first cleavage of pro-opiomelanocortin by pro-opiomelanocortin-converting enzyme to yield 21-23 kDa adrenocorticotropin and beta-lipotropin, but its effect was minimal. The production of adrenocorticotropin from the 21-23 kDa intermediate was stimulated approximately 2.3-fold in the presence of 10 mM Ca2+, and processing of beta-lipotropin to beta-endorphin was stimulated about 1.3-1.4-fold by 5-10 mM Ca2+. The production of gamma-melanotropin-immunoreactive material from bovine N-pro-opiomelanocortin(1-77) was stimulated approximately 1.3-fold at both 100 microM and 1.5-2.0 mM Ca2+. Further characterization of the gamma-melanotropin-immunoreactive material by HPLC demonstrated that the major products were gamma 3-[Lys]melanotropin and gamma 3-melanotropin at both Ca2+ concentrations. These results indicate that pro-opiomelanocortin-converting enzyme is stimulated by Ca2+. (+info)

Plasma immunoreactive corticotrophin and lipotrophin in Cushing's syndrome and Addison's disease. (8/105)

Plasma immunoreactive corticotrophin (ACTH) and lipotrophin (LPH) were measured in patients with raised circulating concentrations from a pituitary or an ectopic source. They were measured again in seven patients after they had received hydrocortisone. Plasma ACTH concentrations were higher than LPH concentrations in patients with a pituitary source of their hormones, whereas this relation was reversed when the source was ectopic. After hydrocortisone administration the half life of immunoreactive ACTH was 40 minutes and that of LPH 95 minutes, resulting in a reversal of the normal relation of ACTH to LPH. The use of two antisera with different specificities for measuring LPH has further shown that pituitary LPH differs from ectopic LPH. Relatively less gamma-LPH than beta-LPH was produced from ectopic sources, the relation being reversed in patients with a pituitary source for their raised concentrations. Measuring plasma LPH as well as ACTH might therefore help in deciding whether a patient with Cushing's syndrome has a pituitary or ectopic source of ACTH, which sometimes presents a difficult clinical problem. (+info)

lipotropin beta. β-LPH. 179-267 lipotropin gamma. γ-LPH. 179-234 ... POMC, ACTH and β-lipotropin are secreted from corticotropes in the anterior lobe (or adenohypophysis) of the pituitary gland in ...

https://en.wikipedia.org/wiki/Adrenocorticotropic_hormone

Smyth, D.G. (2016) Lipotropin & beta-endorphin: a perspective. J. Mol Endocrinol.56, T13-25.. ... Bradbury, A.F., Smyth, D.G., Snell, C.R. Birdsall, N.J.M. and Hulme, E.C. (1976) C-Fragment of lipotropin has a high affinity ... Smyth, D.G., Snell, C.R. and Massey, D.E. (1978) Isolation of the C-fragment and C'-fragment of lipotropin from pig pituitary ... Geisow, M.J., Dostrovsky, J.F.W. and Smyth, D.G. (1977) Analgesic activity of lipotropin C-Fragment depends on carboxyl ...

https://en.wikipedia.org/wiki/Derek_George_Smyth

Lazarus LH, Ling N, Guillemin R (June 1976). "beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and ...

https://en.wikipedia.org/wiki/Leu-enkephalin

... and beta-lipotropin. The subunit ACTH undergoes further cleavage to produce alpha-MSH, the most important MSH for skin ...

https://en.wikipedia.org/wiki/Addison's_disease

Loh YP (September 1986). "Kinetic studies on the processing of human beta-lipotropin by bovine pituitary intermediate lobe pro- ...

https://en.wikipedia.org/wiki/Pro-opiomelanocortin_converting_enzyme

... beta-lipotropin, koji potiče oslobađanje masnih kiselina iz masnog tkiva; mali fragment ACTH-a za koji se misli da poboljšava ... POMC, ACTH i β-lipotropin izlučuju se iz kortikotropa u prednjeg režnja hipofize (ili adenohipofiza), kao odgovor na ... Ostali polipeptidi dobiveni iz POMC uključuju hormon koji stimulira melanocite (alfa- i beta-melanotropin), koji povećava ... memoriju; i beta-endorfin, koji suzbija bol.[1] Upotrebljava se i kao lijek i dijagnostičko sredstvo. ACTH je važna komponenta ...

https://bs.wikipedia.org/wiki/Adrenokortikotropni_hormon

"Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermedia". ... including beta-lipotropin (β-LPH). β-LPH, a pituitary hormone with little opiate activity, is then continually fragmented into ...

https://en.m.wikipedia.org/wiki/Endorphine

... and an NH2-terminal fragment of the adrenocorticotropic hormone/beta-lipotropin precursor from rat pars intermedia". The ...

https://en.wikipedia.org/wiki/Corticotropin-like_intermediate_peptide

... beta-lipotropin/ alfa-melanocit stimulišući hormon/ beta-melanocit stimulišući hormon/ beta-endorfin) ... Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... Alfa-endorfin • Beta-endorfin • Gama-endorfin • α-neo-endorfin • β-neo-endorfin ...

https://sh.wikipedia.org/wiki/Adrenokortikotropni_hormon

... beta-msh MeSH D06.472.699.631.525.690.583.115 - gamma-msh MeSH D06.472.699.631.525.883 - thyrotropin MeSH D06.472.699.631. ... lipotropin MeSH D06.472.699.631.525.690.583 - melanocyte-stimulating hormones MeSH D06.472.699.631.525.690.583.050 - alpha-msh ... beta-msh MeSH D06.472.734.525.690.583.115 - gamma-msh MeSH D06.472.734.525.883 - thyrotropin MeSH D06.472.734.525.883.249 - ... inhibin-beta subunits MeSH D06.472.699.350 - insulin MeSH D06.472.699.350.408 - insulin, isophane MeSH D06.472.699.350.532 - ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D06)

MeSH D12.644.050.200 - defensins MeSH D12.644.050.200.050 - alpha defensins MeSH D12.644.050.200.075 - beta defensins MeSH ... lipotropin MeSH D12.644.548.691.525.690.583 - melanocyte-stimulating hormones MeSH D12.644.548.691.525.690.583.050 - alpha-msh ... beta-msh MeSH D12.644.400.460.115 - gamma-msh MeSH D12.644.400.465 - msh release-inhibiting hormone MeSH D12.644.400.470 - msh- ... gtp-binding protein beta subunits MeSH D12.644.360.375.730 - gtp-binding protein gamma subunits MeSH D12.644.360.375.940 - ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.644)

... beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) ...

https://ml.wikipedia.org/wiki/അഡ്രിനോ_കോർട്ടിക്കോട്രോപ്പിക്_ഹോർമോൺ

beta-Lipotropin at the US National Library of Medicine Medical Subject Headings (MeSH) gamma-Lipotropin at the US National ... In humans, γ-lipotropin, β-MSH, and β-endorphin, are all possible fragments of β-lipotropin. β-Lipotropin is the predominant ... γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids. Gamma lipotropin is ... Lazarus LH, Ling N, Guillemin R (June 1976). "beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and ...

https://en.wikipedia.org/wiki/Lipotropin

... and an NH2-terminal fragment of the adrenocorticotropic hormone/beta-lipotropin precursor from rat pars intermedia". The ...

https://gl.wikipedia.org/wiki/Péptido_intermedio_similar_á_corticotropina

... beta-lipotropin / alfa-melanocit stimulišući hormon / beta-melanocit stimulišući hormon / Beta-endorfin). ... Timus: Timozin (Timozin α1, Timozin beta) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... Beta-endorfin je agonist opioidnih receptora. Postoje dokazi da je on endogeni ligand μ-opioidnog receptora, receptora putem ...

https://sr.wikipedia.org/wiki/Beta-endorfin

... (adrenokortikotropin, beta-lipotropin, alfa-melanocit stimulišući hormon, beta-melanocit stimulišući hormon, beta- ... β-Lipotropin[uredi - уреди , uredi izvor]. β-Lipotropin je 90-aminokiselina dug polipeptid koji je karboksi-terminalni fragment ... γ-Lipotropin[uredi - уреди , uredi izvor]. γ-lipotropin je amino-terminalni peptidni fragment β-lipotropina. Kod ljudi, on ima ... Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ...

https://sh.wikipedia.org/wiki/Lipotropin

beta-hCG is mostly similar to beta-LH, with the exception of a Carboxy Terminus Peptide (beta-CTP) containing four glycosylated ... "Choriogonadotropin subunit beta 3 - Homo sapiens (Human)". UniProt accession number P01233. UniProt Consortium. P0DN86[21-165 ... The β-subunit of hCG gonadotropin (beta-hCG) contains 145 amino acids, encoded by six highly homologous genes that are arranged ... 1qfw: TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT ...

https://en.wikipedia.org/wiki/Beta-HCG

... beta-lipotropin/ alfa-melanocit stimulišući hormon/ beta-melanocit stimulišući hormon/ beta-endorfin). ... Ta grupa obuhvata ACTH, alfa-MSH, beta-MSH i gama-MSH. Svi ti peptidi su produkti presecanja većeg prekursorskog peptida ...

https://sr.m.wikipedia.org/wiki/Melanotropin

α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... hCG beta) and luteinizing hormone beta (hLH beta) in the human testis". FEBS Lett. 343 (3): 229-33. DOI:10.1016/0014-5793(94) ... Beta polipeptid luteinizirajućeg hormona (lutropinska podjedinica beta) je protein koji je kod ljudi kodiran LHB genom.[1][2] ... Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ...

https://sh.wikipedia.org/wiki/Beta_polipeptid_luteinizirajućeg_hormona

α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... Folitropinska podjedinica beta (beta podjedica folikostimulišućeg hormona, FSH-B) je protein koji je kod ljudi kodiran FSHB ... Timus: Timozin (Timozin α1, Beta timozin) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... Svi ti glikoproteini sadrže identičnu alfa podjedinicu i hormon specifičnu beta podjedinicu. Ovaj gen kodira beta podjedinicu ...

https://sr.wikipedia.org/wiki/Folitropinska_podjedinica_beta

beta cells. insulin receptor, IGF-1, IGF-2. Intake of glucose, glycogenesis and glycolysis in liver and muscle from blood ... Lipotropin. LPH. anterior pituitary. Corticotropes. lipolysis and steroidogenesis, stimulates melanocytes to produce melanin ... Inhibit release of insulin from beta cells[5] Inhibit release of glucagon from alpha cells[5] Suppress the exocrine secretory ... pancreatic beta cells. Stimulates the adenylyl cyclase pathway, resulting in increased synthesis and release of insulin ...

https://en.m.wikipedia.org/wiki/List_of_human_hormones

Gregory JJ, Finlay JL (April 1999). "Alpha-fetoprotein and beta-human chorionic gonadotropin: their clinical significance as ... Lipotropin) · வளர் இயக்குநீர் (GH) ... and free beta-subunit of hCG in the human pituitary". J. Clin. ...

https://ta.wikipedia.org/wiki/மனிதக்கரு_வெளியுறை_கருவகவூக்கி

Timus: Timozin (Timozin α1, Timozin beta) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... 1qfw: Tercijarna kompleks humanog horionskog gonadotropina sa FV anti alfa podjedinicom i FV anti beta podjedinicom ... Gregory JJ, Finlay JL (1999). „Alpha-fetoprotein and beta-human chorionic gonadotropin: their clinical significance as tumour ...

https://sr.wikipedia.org/wiki/Humani_horionski_gonadotropin

Proliferation of pancreatic beta cells[edit]. There is evidence that pancreatic beta cells express both the TrkA and p75NTR ... Sun W, Sun C, Lin H, Zhao H, Wang J, Ma H, Chen B, Xiao Z, Dai J (Sep 2009). "The effect of collagen-binding NGF-beta on the ... The term nerve growth factor usually refers to the 2.5S, 26-kDa beta subunit of the protein, the only component of the 7S NGF ... Overview of all the structural information available in the PDB for UniProt: P01138 (Human Beta-nerve growth factor) at the ...

https://en.wikipedia.org/wiki/Nerve_growth_factor

... β-lipotropin, and γ-lipotropin, which contain weak MSH function, can act on the melanocortin 1 receptor. A variant of Cushing's ... In March 2020, Isturisa (osilodrostat) oral tablets a 11-beta-hydroxylase enzyme inhibitor was approved by FDA for treating ...

https://en.wikipedia.org/wiki/Cushing's_syndrome

Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... Beta podjedinice se razlikuju i daju određeni specifični učinak svakom hormonu. Beta lanac FSH sadrži 118 aminokiselina i ... Jedan lanac čini alfa podjedinicu, a drugi beta. Alfa podjedinica FSH sastoji se od 92 aminokiseline i jednaka je alfa ...

https://sh.wikipedia.org/wiki/Folikulostimulirajući_hormon

"Genome-wide binding patterns of thyroid hormone receptor Beta". PLOS One. 9 (2): e81186. Bibcode:2014PLoSO...981186A. doi ...

https://en.wikipedia.org/wiki/Thyroid_hormone

Propeptides: β-Lipotropin (proendorphin). *Prodynorphin. *Proenkephalin. *Pronociceptin. *Proopiomelanocortin (POMC). *Others: ...

https://en.wikipedia.org/wiki/Nalorphine_dinicotinate

Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... Evans AM, Petersen JW, Sekhon GS, DeMars R (May 1989). "Mapping of prolactin and tumor necrosis factor-beta genes on human ...

https://sh.wikipedia.org/wiki/Prolaktin

Propeptides: β-Lipotropin (proendorphin). *Prodynorphin. *Proenkephalin. *Pronociceptin. *Proopiomelanocortin (POMC). *Others: ...

https://en.wikipedia.org/wiki/Opioid_antagonist

Massive overdose can be associated with increased sympathetic activity and thus require treatment with beta-blockers.[18] ...

https://en.wikipedia.org/wiki/Levothyroxine

Studies suggest that neurotrophic factors have a protective role against amyloid beta toxicity.[84] ...

https://en.wikipedia.org/wiki/Brain_derived_neurotrophic_factor

Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... Alfa-endorfin • Beta-endorfin • Gama-endorfin • α-neo-endorfin • β-neo-endorfin ...

https://sh.wikipedia.org/wiki/Gonadotropin-oslobađajući_hormon

https://sh.wikipedia.org/wiki/Steroidni_hormon

برخی از سلول‌های تیرویید به نام سلولهای C یا سلولهای پارافولیکولار، هورمونی پروتئینی به نام کلسی تونین را ترشح می‌کنند که برخلاف هورمون پاراتیروئید (PTH) غلظت خونی کلسیم را کاهش می‌دهد. البته تاثیر این هورمون بر متابولیسم کلسیم در بدن انسان خیلی زیاد نیست.کلسی تونین در روده (کاهش جذب کلسیم)، استخوان (مهار فعالیت سلول اسبتئوکلست و فعال کردن سلول استئوبلاست)، کلیه (افزایش دفع کلسیم و دفع فسفر) تاثیرگذار است. هورمون پاراتورمون از غده پاراتیرویید ترشح می‌شود و موجب اقزایش کلسیم خون می شود. هورمون کلسی تونین از غده تیرویید ترشح می‌شود و با کاهش تجزیه و ...

https://fa.wikipedia.org/wiki/کلسی_تونین

11] Stoga funkcionira kao sinergistički partner insulina, s kojim se kosekretira iz beta ćelija gušterače, kao odgovor na ... Proisletni amiloidni polipeptid (proIAPP, proamilin, proislet protein) proizvodi se u beta ćelijama (β-ćelijama) gušterače kao ... Unutar reakcije fibrilizacije rane, prefibrilarne strukture izuzetno su toksične za kulture beta-ćelija i insulama. Čini se da ... Nedavni rezultati sugeriraju da aminlin, poput srodnog beta-amiloida (abeta) povezanog sa Alzheimerovom olešću, može inducirati ...

https://bs.wikipedia.org/wiki/Amilin

Timus: Timozin (Timozin α1, Timozin beta) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... On deluje kao hormon u telu, koji stimuliše beta ćelije u pankreasu da otpuste više insulina, i istovremeno usmerava ćelije ... Salem AM, Zohny SF, Abd El-Wahab MM, Hamdy R (2007). „Predictive value of osteocalcin and beta-CrossLaps in metastatic breast ...

https://sr.wikipedia.org/wiki/Osteokalcin

Transforming growth factor (Beta) Platelets, Kidney, Placenta Inhibitory effect on cultures tumor cell ...

https://en.wikipedia.org/wiki/Epidermal_growth_factor

... is a peptide of nine amino acids (a nonapeptide) in the sequence cysteine-tyrosine-isoleucine-glutamine-asparagine-cysteine-proline-leucine-glycine-amide (Cys - Tyr - Ile - Gln - Asn - Cys - Pro - Leu - Gly - NH2, or CYIQNCPLG-NH2); its C-terminus has been converted to a primary amide and a disulfide bridge joins the cysteine moieties.[116] Oxytocin has a molecular mass of 1007 Da, and one international unit (IU) of oxytocin is the equivalent of about 2 μg of pure peptide. While the structure of oxytocin is highly conserved in placental mammals, a novel structure of oxytocin was recently reported in marmosets, tamarins, and other new world primates. Genomic sequencing of the gene for oxytocin revealed a single in-frame mutation (thymine for cytosine) which results in a single amino acid substitution at the 8-position (proline for leucine).[117] Since this original Lee et al. paper, two other laboratories have confirmed Pro8-OT and documented additional oxytocin structural variants in ...

https://en.wikipedia.org/wiki/Oxytocin

Timus: Timozin (Timozin α1, Beta timozin) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... Gen timopoetina kodira tri alternativno splajsovane iRNK molekula koji kodiraju proteine sa 75 kDa (alfa), 51 kDa (beta) i 39 ... 2003). „HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication" ...

https://sr.wikipedia.org/wiki/Timopoietin

Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) • Prolaktin • POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) • GH ... Westermark P, Andersson A, Westermark GT (2005). "Is aggregated IAPP a cause of beta-cell failure in transplanted human ... se formira u pankreasnim beta-ćelijama kao peptid sa 67 aminokiselina, 7404 Daltona težak propeptid i on podleže ...

https://sh.wikipedia.org/wiki/Amilin

https://sr.wikipedia.org/wiki/Antidiuretski_hormon

Timus: Timozin (Timozin α1, Beta timozin) · Timopoietin · Timulin Organi za varenje: Želudac: gastrin · grelin · Duodenum: CCK ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolaktin · POMC (CLIP, ACTH, MSH, Endorfini, Lipotropin) · GH ... Ovu reakciju katalizuje 3-beta-HSD (3 beta-hidroksi steroid dehidrogenaza/delta(5)-delta(4)izomeraza). ...

https://sr.wikipedia.org/wiki/Progesteron

Collins P, Rosano GM, Sarrel PM, Ulrich L, Adamopoulos S, Beale CM, McNeill JG, Poole-Wilson PA (July 1995). "17 beta-Estradiol ... Wu CH, Motohashi T, Abdel-Rahman HA, Flickinger GL, Mikhail G (August 1976). "Free and protein-bound plasma estradiol-17 beta ... Wu CH, Motohashi T, Abdel-Rahman HA, Flickinger GL, Mikhail G (August 1976). "Free and protein-bound plasma estradiol-17 beta ... Behl C, Widmann M, Trapp T, Holsboer F (November 1995). "17-beta estradiol protects neurons from oxidative stress-induced cell ...

https://en.wikipedia.org/?title=Estradiol

Activators: beta-Hydroxy beta-methylbutyric acid. *Hydroxynorketamine. *Leucine. *NV-5138. *Inhibitors: Rapalogs: Everolimus ...

https://en.wikipedia.org/wiki/Pancreatic_polypeptide

Off-label prescription of HGH is controversial and may be illegal.[46] Claims for GH as an anti-aging treatment date back to 1990 when the New England Journal of Medicine published a study wherein GH was used to treat 12 men over 60.[47] At the conclusion of the study, all the men showed statistically significant increases in lean body mass and bone mineral density, while the control group did not. The authors of the study noted that these improvements were the opposite of the changes that would normally occur over a 10- to 20-year aging period. Despite the fact the authors at no time claimed that GH had reversed the aging process itself, their results were misinterpreted as indicating that GH is an effective anti-aging agent.[48][49][50] This has led to organizations such as the controversial American Academy of Anti-Aging Medicine promoting the use of this hormone as an "anti-aging agent".[51] A Stanford University School of Medicine meta-analysis of clinical studies on the subject published ...

https://en.wikipedia.org/wiki/Somatotropin

Relationship between structure and activity of some beta-amino ketones". Journal of Medicinal Chemistry. 12 (6): 994-997. doi: ... Propeptides: β-Lipotropin (proendorphin). *Prodynorphin. *Proenkephalin. *Pronociceptin. *Proopiomelanocortin (POMC). *Others: ...

https://en.wikipedia.org/wiki/Dimethylaminopivalophenone

"Schedules of Controlled Substances: Temporary Placement of Butyryl Fentanyl and Beta-Hydroxythiofentanyl into Schedule I" (PDF) ... Propeptides: β-Lipotropin (proendorphin). *Prodynorphin. *Proenkephalin. *Pronociceptin. *Proopiomelanocortin (POMC). *Others: ...

https://en.wikipedia.org/wiki/Butyrfentanyl

Thymus: Thymosin (Thymosin α1, Thymosin beta) · Thymopoietin · Thymulin Digestive system: Stomach: gastrin · ghrelin · Duodenum ... α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolactin · POMC (CLIP, ACTH, MSH, Endorphins, Lipotropin) · GH ...

https://kn.wikipedia.org/wiki/ಆಕ್ಸಿಟೋಸಿನ್‌

december 1.) „Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in humanprostate and evidence for formation of ... 1986) „Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin". Nature 321 (6072), 779- ... január 1.) „The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms". ... vazopresszin · oxitocin · lipotropin. Hipofízis elülső lebenye. gonadotropinok (FSH · LH) · TSH, GH · prolaktin · POMC (→ ACTH ...

https://hu.wikipedia.org/wiki/Aktivin

... a lipotropin of the adenohypophysis of the pituitary gland that contains beta-endorphin as the terminal sequence of 31 amino ... Post the Definition of beta-lipotropin to Facebook Share the Definition of beta-lipotropin on Twitter ... a lipotropin of the adenohypophysis of the pituitary gland that contains beta-endorphin as the terminal sequence of 31 amino ... "Beta-lipotropin." Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/beta- ...

https://www.merriam-webster.com/medical/beta-lipotropin

... and met-enkephalin are all possible fragments of beta-lipotropin. Beta-lipotropin also performs lipid-mobilizing functions such ... N-terminal portion of bovine beta-Lipotropin conjugated to thyroglobulinLabel: UnlabeledAntibody Type: Polyclonal ... In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, ß-endorphin, γ-endorphin, ... Specification:Target: beta LipotropinHost: Rabbit (Rb)Application: Immunohistochemistry (IHC)Product Type: Polyclonal ...

https://www.medico.co.kr/product-page/beta-lipotropin

https://en.wikipedia.org/wiki/Adrenocorticotropic_hormone

Three similar peptides called alpha-, beta-, and gamma-melanocyte stimulating hormones (α-, β-, and γ-MSH) are also cut from ... A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. Cell Metab. 2006 Feb;3(2 ... A role for beta-melanocyte-stimulating hormone in human body-weight regulation. Cell Metab. 2006 Feb;3(2):141-6. Citation on ... beta-MSH. *CLIP. *COLI_HUMAN. *corticotropin-like intermediary peptide. *corticotropin-lipotropin. *gamma-LPH ...

https://medlineplus.gov/genetics/gene/pomc/

Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides. ... TruStrip WBV Human Beta Actin Protein Quantitation & Western Blot Validation Strips (10/pk). ... TruStrip WBV Beta-Galactosidase Fusion protein quantitation & Western Blot Validation Strips (10/pk). ...

http://kancrn.org/optimizing-modified-mrna-in-vitro-synthesis-protocol-for-heart-gene-therapy/

Lipotropin beta antibody. *Lipotropin gamma antibody. *LPH antibody. *Melanotropin alpha antibody. *Melanotropin antibody ...

https://www.abcam.com/pomc-antibody-ab180766.html

Rabbit polyclonal beta Endorphin antibody validated for ICC/IF and tested in Human, Mouse and Rat. Immunogen corresponding to ... Antiserum to beta Endorphin was raised in rabbits by using the N-terminal portion of bovine beta Endorphin conjugated to ... Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous ...

http://www.abcam.com/beta-endorphin-antibody-ab10339.html

1. Beta-lipotropin. 2. Gamma-lipotropin. 3. Beta-endorphin. 4. Beta-MSH. 5. ACTH. 6. Alpha-MSH. 7. CLIP ... Beta receptors: relaxation and dilatation of blood vessels, heart rate increase, reduction of gut motility, dilation of lungs, ...

https://www.brainscape.com/flashcards/lecture-5-hormonal-regulation-of-the-adre-5360557/packs/8053412

https://en.wikipedia.org/wiki/Lipotropin

beta-Lipotropin: localization of cells and axons in rat brain by immunocytochemistry. . Proc. Natl. Acad. Sci. USA 74, 5155- ...

https://www.nature.com/articles/nn.2545?error=cookies_not_supported&code=a676696a-a0f3-4d5b-8bfb-ac572c9a49c6

Genazzani, A.R., Facchinetti, F. and Parrini, D. (1981). Beta lipotropin and beta-endorphin plasma levels during pregnancy. ... Wardlaw, S.L. and Frantz, A.G. (1980). Effects of swimming stress on brain beta-endorphins and ACTH. Clin. Res., 28 (abst.), ... Rossier, J., French, E.D., Rivier, C. Ling, N., Guillemin, R. and Bloom, F.E. (1977). Foot-shock-induced stress increases beta- ... McCain, H.W., Lamster, I.B., Bozzone, J.M. and Grbic, J.T. (1982). Beta-endorphin modulates human immune activity via non- ...

https://link.springer.com/chapter/10.1007/978-1-349-07834-9_14

Browse our Melanotropin beta product catalog backed by our Guarantee+. ... PTMs for Melanotropin beta. Learn more about PTMs related to Melanotropin beta.. Cleavage. Phosphorylation. Acetylation. ... Corticotropin-lipotropin. *beta-MSH. *proopiomelanocortin preproprotein. *beta-LPH. *pro-opiomelanocortin. *alpha-melanocyte- ... Diseases related to Melanotropin beta. Discover more about diseases related to Melanotropin beta.. Pituitary Diseases. Obesity ...

https://www.novusbio.com/common-name/melanotropin-beta

1. Lipotropin - precursor to what?. 2. Beta-endorphin and met-enkephalin - opiods with what effects? ...

https://www.brainscape.com/flashcards/26-posterior-lobe-pituitary-604775/packs/850232

Beta-Lipotropin (1-10), porcine. Morphine-like substance. 77875-68-4. BNTX maleate. 864461-31-4. ... but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive ... but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive ...

http://www.genecards.org/cgi-bin/carddisp.pl?gene=OPRK1

... beta-endorphin + beta-lipotropin) in plasma at rest and during an acute exercise on a bicycle ergometer requiring 80% and 100% ... 0/Endorphins; 60617-12-1/beta-Endorphin; 9002-60-2/Adrenocorticotropic Hormone; 9015-71-8/Corticotropin-Releasing Hormone; 9035 ...

http://www.biomedsearch.com/nih/Plasma-corticotropin-releasing-hormone-endorphins/2840309.html

1979) Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature 278(5703):423-427. ...

https://www.pnas.org/content/110/39/15521.full?sid=8b77d212-390e-4470-9e34-991e77479d4c

Smyth, D.G. (2016) Lipotropin & beta-endorphin: a perspective. J. Mol Endocrinol.56, T13-25.. ... Bradbury, A.F., Smyth, D.G., Snell, C.R. Birdsall, N.J.M. and Hulme, E.C. (1976) C-Fragment of lipotropin has a high affinity ... Smyth, D.G., Snell, C.R. and Massey, D.E. (1978) Isolation of the C-fragment and C-fragment of lipotropin from pig pituitary ... Geisow, M.J., Dostrovsky, J.F.W. and Smyth, D.G. (1977) Analgesic activity of lipotropin C-Fragment depends on carboxyl ...

https://en.wikipedia.org/wiki/Derek_George_Smyth

... beta-MSH; corticotropin-like intermediary peptide; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin ... and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all ... and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have ... Protein Aliases: adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte-stimulating hormone; alpha-MSH; beta- ...

https://www.thermofisher.com/antibody/product/ACTH-Antibody-6Y8-Monoclonal/MA5-18042

... beta-MSH; corticotropin-like intermediary peptide; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin ... beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); ... proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta) ... Protein Aliases: Adrenocorticotropic Hormone; adrenocorticotropin; alpha-melanocyte-stimulating hormone; alpha-MSH; beta- ...

https://www.thermofisher.com/antibody/product/Adrenocorticotropic-Hormone-Antibody-56-Monoclonal/MA1-27354

https://bs.wikipedia.org/wiki/Adrenokortikotropni_hormon

... beta-lipotropin do also nt.. Although amount day has been reported to induce severe few doses, otc we did not see any immune ...

http://www.vaporizerdepot.com/aromed-replacement-halogen-bulb.html

1981) Physical conditioning facilitates the exercise-induced secretion of beta-endorphin and beta-lipotropin in women. N Engl J ...

https://www.pnas.org/content/112/42/13105.long

Figure 82 shows the successful purification of beta-lipotropin fragment 1-10 (MW 950, Sigma) achieved by using high pH ... At pH 2 the contaminants are eluted in the beta-lipotropin peak. ...

https://www.sigmaaldrich.com/technical-documents/protocols/biology/hydrophobic-interaction/rpc-purification-options-with-source.html

60 YEARS OF POMC: Lipotropin and beta-endorphin: A perspective. J. Mol. Endocrinol. 56, T13-T25 (2016).. ...

https://advances.sciencemag.org/content/5/9/eaax1342

Also written beta-lipotrophin, -lipotropin, or -lipotrophin. It is given reinforcement (3) in bayesian inference n. Another ...

https://dsaj.org/buyingmg/taking-viagra-and-propecia/200/

Peptides (beta-endorphin, methionine-enkephalin, beta-lipotropin, granulocyte inhibiting proteins I and II, degranulation- ...

https://emedicine.medscape.com/article/1175425-clinical

1993). Altered ratios of beta-endorphin: Beta-lipotropin released from anterior lobe corticotropes with increased secretory ... 1979). Adrenocorticotropin and beta-lipotropin in the hypothalamus - localization in the same arcuate neurons by sequential ... 2012). Beta-endorphin antagonizes the effects of alpha-MSH on food intake and body weight. Endocrinology, 153(9), 4246-4255. ... Synthesis of beta-endorphin, ACTH, and alpha-MSH. Existence of POMC-related sequences. Annals of the New York Academy of ...

https://link.springer.com/chapter/10.1007%2F978-3-319-89506-2_11

https://en.m.wikipedia.org/wiki/Endorphine

Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells ... Adrenocorticotropin; alpha or beta or gamma Melanocyte Stimulating Hormone (MSH) or Melanotropin; beta-Endorphin; beta or gamma ... POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP ... pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive ...

https://biotium.com/product/acth-recombinant-monoclonal-rabbit-antibody-clip-2040r/

Lipotropin (adrenokortikotropin, beta-lipotropin, alfa-melanocit stimulišući hormon, beta-melanocit stimulišući hormon, beta- ... β-Lipotropin[uredi - уреди , uredi izvor]. β-Lipotropin je 90-aminokiselina dug polipeptid koji je karboksi-terminalni fragment ... γ-Lipotropin[uredi - уреди , uredi izvor]. γ-lipotropin je amino-terminalni peptidni fragment β-lipotropina. Kod ljudi, on ima ... Timus: Timozin (Timozin α1, Timozin beta) • Timopoietin • Timulin Organi za varenje: Želudac: gastrin • grelin • Duodenum: CCK ...

https://sh.wikipedia.org/wiki/Lipotropin

The anterior pituitary gland produces the pro-hormone POMC, which undergoes cleavage to adrenocorticotropin (ACTH) and β-lipotropin (β-LPH) which is a 90 amino acid polypeptide that is the carboxy-terminal fragment of POMC. (medico.co.kr)
POMC , ACTH and β-lipotropin are secreted from corticotropes in the anterior lobe (or adenohypophysis ) of the pituitary gland in response to the hormone corticotropin-releasing hormone (CRH) released by the hypothalamus . (wikipedia.org)
The hypothalamic-pituitary response to exercise was studied in 12 amenorrheic and in 9 eumenorrheic athletes by comparing the concentrations of corticotropin-releasing hormone (CRH), corticotropin (ACTH), and endorphins (beta-endorphin + beta-lipotropin) in plasma at rest and during an acute exercise on a bicycle ergometer requiring 80% and 100% of the maximal oxygen uptake (VO2 max). (biomedsearch.com)
The anterior pituitary gland produces the pro-hormone POMC, which is then cleaved again to form adrenocorticotropin (ACTH) and β-lipotropin (β-LPH). (wikipedia.org)
POMC , ACTH i β-lipotropin izlučuju se iz kortikotropa u prednjeg režnja hipofize (ili adenohipofiza ), kao odgovor na kortikotropin-oslobađajući hormon (CRH) kojeg oslobađa hipotalamus . (wikipedia.org)
The POMC gets cleaved into beta-lipotropin, ACTH and gamma MSH after production in the anterior pituitary gland. (exclusivepapers.com)
1982 gamma MSH, a putative hormone in the N-terminal region of the ACTH/beta-endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. (eurekamag.com)
Rat median eminence extracts enhanced the release of gamma MSH-like immunoreactivity (gamma MSH-LI) concomitant with ACTH-like immunoreactivity (ACTH-LI) and beta-EP-like immunoreactivity (beta-EP-LI). (eurekamag.com)
Dexamethasone suppressed the release of gamma MSH-LI as well as ACTH-LI and beta-EP-LI. (eurekamag.com)
The 31K gamma MSH coincided with the migration position of 31K ACTH of 31K beta-EP, and 21-23K gamma MSH coincided with the position of 21-23K ACTH on SDS-PAGE. (eurekamag.com)
The 16-17K gamma MSH coincided with the mouse 16K fragment (reported by Eipper and Mains) of ACTH-beta-lipotropin precursor protein in the migration in SDS-PAGE and in immunoreactivity to anti-gamma MSH antiserum. (eurekamag.com)
These results suggest that AtT-20/D16v cells produce gamma MSH-LIs with molecular weights of 31K, 21-23K, 16-17K, 13-14K, and 3.8K, and they are secreted concomitantly with ACTH-LI and beta-EP-LI. (eurekamag.com)
Endogenous opioid precursor that contains the met-enkephalin sequence, beta-endorphins, and several nonopioid peptides including ACTH, beta-lipotropin, and melanocyte-stimulating hormone. (pharmacology2000.com)
These tumors secrete large quantities of alpha melanocyte-stimulating hormone, the normal product of the pars intermedia, as well as adrenocorticotropic hormone (ACTH), beta-endorphin, beta-lipotropin, and corticotropin-like intermediate peptide (CLIP). (tufts.edu)
1. The possible correlation between secretions of adrenocorticotropic hormone (ACTH) and of ß-lipotropin (ß-LPH), two pro-opiomelanocortin (POMC)-derived peptides, was investogated in 27 normal subjects under basal conditions (circadian rhythmz0, after the administration of 1 mg dexamethasone and in tests involving acute (human corticotropin releasing hormone, hCRG, and insulin tolerance test, ITT) and chronic (metyrapone) simulation. (bvsalud.org)

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC). (medico.co.kr)
Three similar peptides called alpha-, beta-, and gamma-melanocyte stimulating hormones (α-, β-, and γ-MSH) are also cut from the POMC protein. (medlineplus.gov)
Lipotropin is the name for two hormones produced by the cleavage of pro-opiomelanocortin (POMC). (wikipedia.org)
β-Lipotropin is a 90-amino acid polypeptide that is the carboxy-terminal fragment of POMC. (wikipedia.org)
POMC is fragmented into many different smaller proteins, including beta-lipotropin (β-LPH). (wikipedia.org)
Lipotropin (adrenokortikotropin, beta-lipotropin, alfa-melanocit stimulišući hormon, beta-melanocit stimulišući hormon, beta-endorfin) je hormon koji se formira prsecanjem proopiomelanokortina (POMC). (wikipedia.org)
β-Lipotropin je 90- aminokiselina dug polipeptid koji je karboksi-terminalni fragment POMC-a. (wikipedia.org)
The production of beta-MSH occurs in humans but not in mice or rats due to the absence of the enzymatic processing site in the rodent POMC. (bionity.com)
Entrez Gene: POMC proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin). (bionity.com)

Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides. (kancrn.org)
β-Lipotropin can be cleaved into smaller peptides. (wikipedia.org)
These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. (thermofisher.com)

Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. (abcam.com)
γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. (wikipedia.org)
Condition-dependent presence of beta-lipotropin-like peptide in human keratinocytes. (naver.com)
beta-hCG is mostly similar to beta-LH, with the exception of a Carboxy Terminus Peptide (beta-CTP) containing four glycosylated serine residues that is responsible for hCG's longer half-life. (wikipedia.org)
When AtT-20 cells were stimulated with KCI or forskolin, the ratio of d- to H-labeled γ-lipotropin in the medium decreased, suggesting that the older peptide was in a compartment that could be released upon the appropriate stimulation. (elsevier.com)
CSF levels of CRF, β-lipotropin, vasoactive intestinal peptide, adrenocorticotropic hormone, and somatostatin were highly correlated with one another, suggesting that a common factor is responsible for a significant proportion of the observed variance in their CSF levels. (elsevier.com)

In a classic series of papers from 1975-1982, he and his collaborators (26-34) showed that the C-terminal fragment of lipotropin, discovered by Smyth in the pituitary (35-37), was an endogenously expressed opiate (38). (wikipedia.org)
γ-lipotropin je amino-terminalni peptidni fragment β-lipotropina. (wikipedia.org)

Gamma lipotropin is identical to the first 56 amino acid sequences of β-lipotropin. (wikipedia.org)

Prednisone administration was associated with decreases in cerebrospinal fluid levels of corticotropin, norepinephrine, beta-endorphin, beta-lipotropin, and somatostatinlike immunoreactivity. (nih.gov)
The DNA sequences resulting from both sequencing methods were compared to each other, to the human Alu sequences, and to a bovine repetitious DNA sequence located near the bovine corticotropin-beta-lipotropin precursor gene (Watanabe, et al. (iastate.edu)
1982. Structural analysis of repetitive DNA sequences in the bovine corticotropin-B-lipotropin precursor gene region. (iastate.edu)

G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. (genecards.org)
Evidence shows that β-Lipotropin is metabolized into endorphins that can greatly affect mood and behavior and is thus regarded as a prohormone. (wikipedia.org)

Immunohistochemistry (Frozen sections) - Anti-beta Endorphin antibody [B 31.15] (ab54205) Image from Ranganathan S et al. (abcam.com)
Melanotropin beta Antibody (CLIP/1. (novusbio.com)
Beta-endorphin Monoclonal antibody specifically detects Beta-endorphin in Human samples. (fishersci.com)

Antiserum to beta Endorphin was raised in rabbits by using the N-terminal portion of bovine beta Endorphin conjugated to thyroglobulin. (acris-antibodies.com)

Beta-lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis. (medico.co.kr)
adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. (thermofisher.com)

The Melanotropin beta gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. (novusbio.com)
Learn more about PTMs related to Melanotropin beta. (novusbio.com)
Discover related pathways, diseases and genes to Melanotropin beta. (novusbio.com)

Overexpression of proSAAS in AtT-20 cells reduced the ratio of d- to H-labeled γ-lipotropin, consistent with the proposed role of proSAAS as an endogenous inhibitor of prohormone convertase-1. (elsevier.com)

It is heterodimeric , with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and β (beta) subunit that is unique to hCG. (wikipedia.org)
The β-subunit of hCG gonadotropin ( beta-hCG ) contains 145 amino acids, encoded by six highly homologous genes that are arranged in tandem and inverted pairs on chromosome 19q 13.3 - CGB ( 1 , 2 , 3 , 5 , 7 , 8 ). (wikipedia.org)

Although the N-terminal 5 amino acids of beta-endorphin are identical to the sequence of Met-enkephalin, it is not generally thought that beta-endorphin is converted into Met-enkephalin. (bionity.com)

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. (springer.com)
In the present study, we labeled cell lines with L-leucine containing 10 deuterium residues (d 10 -Leu) and used mass spectrometry to measure the biosynthetic rate of γ-lipotropin in the AtT-20 cell line and insulin in the INS-1 cell line. (elsevier.com)

ab54205, staining beta Endorphin in anterior (upper) and intermediate (lower) lobes of Wistar rat pituitary gland tissue by Immunohistochemistry (Frozen sections). (abcam.com)
β-Lipotropin is the predominant opioid of the anterior human and rat pituitary gland. (wikipedia.org)

Plasma immunoreactive beta-endorphin is elevated in uraemia. (umassmed.edu)

In three naloxone-treated dogs, gel chromatography of pooled basal and peak plasma revealed a preponderance of β-lipotropin compared to β-endorphin.To determine the site of stimulation of βEI by opiates and opioids, a series of rat anterior pituitary incubations were performed. (elsevier.com)

Beta endorphin and Met enkephalin are endogenous opiates. (acris-antibodies.com)

News extras per delayed doses genes, price mg 40 prednisone en current part effects per complaint drugs. (greenwoodplazaja.com)

Full length native human beta Endorphin. (abcam.com)
Beta-endorphin and metenkephalin stimulate human peripheral blood mononuclear cell chemotaxis. (springer.com)
Diagramm of the ELISA kit to detect Human beta -EPwith the optical density on the x-axis and the concentration on the y-axis. (antikoerper-online.de)

29 Endorphin beta (beta-EP) ELISA Kits from 5 manufacturers are available on www.antibodies-online.com. (antibodies-online.com)

The matters are currently under investigation due to the relationship between Lipotropin and growth hormones, as noted by club medical staff. (wikipedia.org)

Merriam-Webster.com Medical Dictionary , Merriam-Webster, https://www.merriam-webster.com/medical/beta-lipotropin. (merriam-webster.com)

However, no subsequent studies have been published that support these early findings and no receptor has been identified for β-lipotropin. (wikipedia.org)

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Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands. (1/105)

Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin. (2/105)

beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. (3/105)

Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. (4/105)

Altered processing of pro-orphanin FQ/nociceptin and pro-opiomelanocortin-derived peptides in the brains of mice expressing defective prohormone convertase 2. (5/105)

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes. (6/105)

Effect of calcium ions on the processing of pro-opiomelanocortin by bovine intermediate lobe pro-opiomelanocortin-converting enzyme. (7/105)

Plasma immunoreactive corticotrophin and lipotrophin in Cushing's syndrome and Addison's disease. (8/105)

beta-Lipotropin

Endorphins

Interleukin-1beta

beta 2-Microglobulin

Adrenal Cortex

Encyclopedias as Topic

Adrenocorticotropic Hormone

Zona Fasciculata

Receptors, Corticotropin

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Receptor, Melanocortin, Type 2

beta-Endorphin

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Melanocyte-Stimulating Hormones

Pituitary Hormones, Anterior

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Interleukin-16

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T-Lymphocytes

Lymphocyte Activation

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Yucca

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Pro-Opiomelanocortin

Enkephalin, Methionine

Enkephalins

Secretory Vesicles

Acupuncture Therapy

Acupuncture

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Ethanol

Substance Withdrawal Syndrome

Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands. (1/105)

Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin. (2/105)

beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. (3/105)

Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. (4/105)

Altered processing of pro-orphanin FQ/nociceptin and pro-opiomelanocortin-derived peptides in the brains of mice expressing defective prohormone convertase 2. (5/105)

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes. (6/105)

Effect of calcium ions on the processing of pro-opiomelanocortin by bovine intermediate lobe pro-opiomelanocortin-converting enzyme. (7/105)

Plasma immunoreactive corticotrophin and lipotrophin in Cushing's syndrome and Addison's disease. (8/105)

High Purity [Tyr9]-β-MSH, porcine; (Tyr49)-β-Lipotropin (41-58), porcine for Various Application Researchers - Elabscience

ChemIDplus - 17206-74-5 - KTTLFJFYWIMKGW-UHFFFAOYSA-N - beta-Melanotropin (pig), 2-l-serine- - Similar structures search,...

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