Beta glucosidase. Medical search

An exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of GLUCOSE.

An enzyme that catalyzes the endohydrolysis of 1,6-alpha-glucosidic linkages in isomaltose and dextrins produced from starch and glycogen by ALPHA-AMYLASES. EC 3.2.1.10.

Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II.

Enzymes that hydrolyze O-glucosyl-compounds. (Enzyme Nomenclature, 1992) EC 3.2.1.-.

An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. As a glucosidase it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III.

Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE.

Six-carbon pyranose sugars in which the OXYGEN is replaced by a NITROGEN atom.

A plant genus of the APOCYNACEAE or dogbane family. Alkaloids from plants in this genus have been used as tranquilizers and antihypertensive agents. RESERPINE is derived from R. serpentina.

An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.

A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES found on newly synthesized proteins. It may play role in PROTEIN FOLDING or retention and degradation of misfolded proteins in the endoplasmic reticulum.

A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)

An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.

A disaccharide consisting of two glucose units in an alpha (1-6) glycosidic linkage.

The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.

The sequence of carbohydrates within POLYSACCHARIDES; GLYCOPROTEINS; and GLYCOLIPIDS.

One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.

An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.

Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.

Enzymes that catalyze the hydrolysis of N-acylhexosamine residues in N-acylhexosamides. Hexosaminidases also act on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES.

An autosomal recessively inherited glycogen storage disease caused by GLUCAN 1,4-ALPHA-GLUCOSIDASE deficiency. Large amounts of GLYCOGEN accumulate in the LYSOSOMES of skeletal muscle (MUSCLE, SKELETAL); HEART; LIVER; SPINAL CORD; and BRAIN. Three forms have been described: infantile, childhood, and adult. The infantile form is fatal in infancy and presents with hypotonia and a hypertrophic cardiomyopathy (CARDIOMYOPATHY, HYPERTROPHIC). The childhood form usually presents in the second year of life with proximal weakness and respiratory symptoms. The adult form consists of a slowly progressive proximal myopathy. (From Muscle Nerve 1995;3:S61-9; Menkes, Textbook of Child Neurology, 5th ed, pp73-4)

Oligosaccharides containing three monosaccharide units linked by glycosidic bonds.

A species of HENIPAVIRUS, closely related to HENDRA VIRUS, which emerged in Peninsular Malaysia in 1998. It causes a severe febrile VIRAL ENCEPHALITIS in humans and also encephalitis and RESPIRATORY TRACT INFECTIONS in pigs. Fruit bats (PTEROPUS) are the natural host.

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose.

Proteins obtained from ESCHERICHIA COLI.

Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.

Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.

A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.

An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.

A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.

Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.

The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)

Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).

A family of glycosidases that hydrolyse crystalline CELLULOSE into soluble sugar molecules. Within this family there are a variety of enzyme subtypes with differing substrate specificities that must work together to bring about complete cellulose hydrolysis. They are found in structures called CELLULOSOMES.

A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.

The process of cleaving a chemical compound by the addition of a molecule of water.

An endocellulase with specificity for the hydrolysis of 1,4-beta-glucosidic linkages in CELLULOSE, lichenin, and cereal beta-glucans.

Cholestane derivatives containing a fused lactone ring at the 16,17-position and a spiroglycosidic linkage at C-22. Members include sarsaponin, DIOSGENIN and yamogenin.

A plant genus of the family Costaceae (sometimes classified in Zingiberaceae), order Zingiberales, subclass Zingiberidae, class Liliopsida (monocotyledons). It is a source of SAPONINS and furostanol glycosides.

A plant genus of the family ZYGOPHYLLACEAE. Members contain steroidal saponins. Ingestion by grazing animals causes PHOTOSENSITIVITY DISORDERS called geeldikkop (yellow thick head) in South Africa.

Root-like underground horizontal stem of plants that produces shoots above and roots below. Distinguished from true roots which don't have buds and nodes. Similar to true roots in being underground and thickened by storage deposits.

Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)

A plant genus of the family LILIACEAE. Members contain benzoquinones, steroidal saponin, and ribosome-inactivating proteins.

Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.

The DNA binding site of the Dof protein NtBBF1 is essential for tissue-specific and auxin-regulated expression of the rolB oncogene in plants. (1/814)

The Dof proteins are a large family of plant transcription factors that share a single highly conserved zinc finger. The tobacco Dof protein NtBBF1 was identified by its ability to bind to regulatory domain B in the promoter of the rolB oncogene. In this study, we show that the ACT T TA target sequence of NtBBF1 in domain B is necessary for tissue-specific expression of rolB. beta-Glucuronidase (GUS) activity of tobacco plants containing a rolB promoter-GUS fusion with a mutated NtBBF1 target sequence within domain B is almost completely suppressed in apical meristems and is severely abated in the vascular system. The ACT T TA motif is shown here also to be one of the cis-regulatory elements involved in auxin induction of rolB. The pattern of NtBBF1 expression in plants is remarkably similar to that of rolB, except in mesophyll cells of mature leaves, in which only NtBBF1 expression could be detected. Ectopic expression of rolB in mesophyll cells was achieved by particle gun delivery if the NtBBF1 binding sequence was intact. These data provide evidence that in the plant, a Dof protein DNA binding sequence acts as a transcriptional regulatory motif, and they point to NtBBF1 as the protein involved in mediating tissue-specific and auxin-inducible expression of rolB. (+info)

Stochastic and nonstochastic post-transcriptional silencing of chitinase and beta-1,3-glucanase genes involves increased RNA turnover-possible role for ribosome-independent RNA degradation. (2/814)

Stochastic and nonstochastic post-transcriptional gene silencing (PTGS) in Nicotiana sylvestris plants carrying tobacco class I chitinase (CHN) and beta-1,3-glucanase transgenes differs in incidence, stability, and pattern of expression. Measurements with inhibitors of RNA synthesis (cordycepin, actinomycin D, and alpha-amanitin) showed that both forms of PTGS are associated with increased sequence-specific degradation of transcripts, suggesting that increased RNA turnover may be a general feature of PTGS. The protein synthesis inhibitors cycloheximide and verrucarin A did not inhibit degradation of CHN RNA targeted for PTGS, confirming that PTGS-related RNA degradation does not depend on ongoing protein synthesis. Because verrucarin A, unlike cycloheximide, dissociates mRNA from ribosomes, our results also suggest that ribosome-associated RNA degradation pathways may not be involved in CHN PTGS. (+info)

Molecular cloning and expression of the novel fungal beta-glucosidase genes from Humicola grisea and Trichoderma reesei. (3/814)

A novel fungal beta-glucosidase gene (bgl4) and its homologue (bgl2) were cloned from the cellulolytic fungi Humicola grisea and Trichoderma reesei, respectively. The deduced amino acid sequences of H. grisea BGL4 and T. reesei BGL2 comprise 476 and 466 amino acids, respectively, and share 73.1% identity. These beta-glucosidases show significant homology to plant beta-glucosidases belonging to the beta-glucosidase A (BGA) family. Both genes were expressed in Aspergillus oryzae, and the recombinant beta-glucosidases were purified. Recombinant H. grisea BGL4 is a thermostable enzyme compared with recombinant T. reesei BGL2. In addition to beta-glucosidase activity, recombinant H. grisea BGL4 showed a significant level of beta-galactosidase activity, while recombinant T. reesei BGL2 showed weak beta-galactosidase activity. Cellulose saccharification by Trichoderma cellulases was improved by the addition of recombinant H. grisea BGL4. (+info)

Properties of beta-glucosidase in cultured skin fibroblasts from controls and patients with Gaucher disease. (4/814)

Membrane-bound beta-glucosidase from cultured skin fibroblasts can be solubilized in an active form by treatment of membrane preparations with a mixture of Triton X-100 and sodium taurocholate. Several properties of the solubilized enzyme have been studied in fibroblasts from normal, healthy individuals and from 14 patients with different clinical forms of Gaucher disease. The patients studied were classified as follows: group 1 consisted of 10 chronic patients, all (with one exception) of Ashkenazi Jewish origin; group 2 consisted of three black American patients with severe visceral symptoms, manifest from early childhood, but with no apparent neurological involvement; and group 3 consisted of a single white patient with the classical infantile form of the disease. Specific beta-glucosidase activity ranged from 6.6% to 16.5% mean control value in group 1 patients and from 4.1% to 5.8% in groups 2 and 3. When compared with the enzyme from control fibroblasts, the enzyme from chronic Gaucher patients (group 1) was more rapidly inactivated at 50 degrees C, had an altered pH curve, was less effectively inhibited by deoxycorticosterone-beta-glucoside, and was more effectively inhibited by deoxycorticosterone. The enzyme from patients in groups 2 and 3 was qualitatively indistinguishable from the control enzyme in terms of these parameters. No differences in Km (4-methylumbelliferyl-beta-glucoside) or sedimentation coefficient were found between the beta-glucosidases from control and Gaucher cells. The results demonstrate that cells from Ashkenazi Jewish patients with the chronic form of Gaucher disease contain a structurally altered form of beta-glucosidase. This enzyme differs both from normal beta-glucosidase and from the residual enzyme in patients of different ethnic origin and with clinically more severe forms of the disease. (+info)

Growth of Azospirillum irakense KBC1 on the aryl beta-glucoside salicin requires either salA or salB. (5/814)

The rhizosphere nitrogen-fixing bacterium Azospirillum irakense KBC1 is able to grow on pectin and beta-glucosides such as cellobiose, arbutin, and salicin. Two adjacent genes, salA and salB, conferring beta-glucosidase activity to Escherichia coli, have been identified in a cosmid library of A. irakense DNA. The SalA and SalB enzymes preferentially hydrolyzed aryl beta-glucosides. A Delta(salA-salB) A. irakense mutant was not able to grow on salicin but could still utilize arbutin, cellobiose, and glucose for growth. This mutant could be complemented by either salA or salB, suggesting functional redundancy of these genes in salicin utilization. In contrast to this functional homology, the SalA and SalB proteins, members of family 3 of the glycosyl hydrolases, show a low degree of amino acid similarity. Unlike SalA, the SalB protein exhibits an atypical truncated C-terminal region. We propose that SalA and SalB are representatives of the AB and AB' subfamilies, respectively, in glycosyl hydrolase family 3. This is the first genetic implication of this beta-glucosidase family in the utilization of beta-glucosides for microbial growth. (+info)

Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis. (6/814)

We have screened for proteins that interact with v-SNAREs of the late secretory pathway in the yeast Saccharomyces cerevisiae. A novel protein, designated Vsm1, binds tightly to the Snc2 v-SNARE in the two-hybrid system and can be coimmunoprecipitated with Snc1 or Snc2 from solubilized yeast cell extracts. Disruption of the VSM1 gene results in an increase of proteins secreted into the medium but does not affect the processing or secretion of invertase. In contrast, VSM1 overexpression in cells which bear a temperature-sensitive mutation in the Sec9 t-SNARE (sec9-4 cells) results in the accumulation of non-invertase-containing low-density secretory vesicles, inhibits cell growth and the secretion of proteins into the medium, and blocks rescue of the temperature-sensitive phenotype by SNC1 overexpression. Yet, VSM1 overexpression does not affect yeast bearing a sec9-7 allele which, in contrast to sec9-4, encodes a t-SNARE protein capable of forming a stable SNARE complex in vitro at restrictive temperatures. On the basis of these results, we propose that Vsm1 is a novel v-SNARE-interacting protein that appears to act as negative regulator of constitutive exocytosis. Moreover, this regulation appears specific to one of two parallel exocytic paths which are operant in yeast cells. (+info)

Cellobiose transport by mixed ruminal bacteria from a Cow. (7/814)

The transport of cellobiose in mixed ruminal bacteria harvested from a holstein cow fed an Italian ryegrass hay was determined in the presence of nojirimycin-1-sulfate, which almost inhibited cellobiase activity. The kinetic parameters of cellobiose uptake were 14 microM for the Km and 10 nmol/min/mg of protein for the Vmax. Extracellular and cell-associated cellobiases were detected in the rumen, with both showing higher Vmax values and lower affinities than those determined for cellobiose transport. The proportion of cellobiose that was directly transported before it was extracellularly degraded into glucose increased as the cellobiose concentration decreased, reaching more than 20% at the actually observed levels of cellobiose in the rumen, which were less than 0.02 mM. The inhibitor experiment showed that cellobiose was incorporated into the cells mainly by the phosphoenolpyruvate phosphotransferase system and partially by an ATP-dependent and proton-motive-force-independent active transport system. This finding was also supported by determinations of phosphoenolpyruvate phosphotransferase-dependent NADH oxidation with cellobiose and the effects of artificial potentials on cellobiose transport. Cellobiose uptake was sensitive to a decrease in pH (especially below 6.0), and it was weakly but significantly inhibited in the presence of glucose. (+info)

Transcriptional regulation in the hyperthermophilic archaeon Pyrococcus furiosus: coordinated expression of divergently oriented genes in response to beta-linked glucose polymers. (8/814)

The genetic organization, expression, and regulation of the celB locus of the hyperthermophilic archaeon Pyrococcus furiosus were analyzed. This locus includes the celB gene, which codes for an intracellular beta-glucosidase, and a divergently orientated gene cluster, adhA-adhB-lamA, which codes for two alcohol dehydrogenases and an extracellular beta-1,3-endoglucanase that is transcribed as a polycistronic messenger (the lamA operon). During growth of P. furiosus on either the beta-1,4-linked glucose dimer cellobiose or the beta-1,3-linked glucose polymer laminarin, the activities of both beta-glucosidase and endoglucanase were increased at least fivefold compared with levels during growth on maltose or pyruvate. Northern blot analysis revealed an enhanced transcription of both the celB gene and the lamA operon in the presence of these glucose-containing substrates. The in vivo and in vitro transcription initiation sites of both the celB gene and the lamA operon were identified 25 nucleotides downstream of conserved TATA box motifs. A number of repeating sequences have been recognized in the celB-adhA intergenic region, some of which might be part of a transcriptional regulator-binding site. (+info)

"Entrez Gene: GBAP glucosidase, beta; acid, pseudogene". Beutler E, West C, Gelbart T (1992). "Polymorphisms in the human ... Glucosidase, beta; acid, pseudogene, also known as GBAP, is a human gene. GRCh38: Ensembl release 89: ENSG00000160766 - Ensembl ...

https://en.wikipedia.org/wiki/GBAP_(gene)

... beta-glucosidase (EC 3.2.1.21); beta-galactosidase (EC 3.2.1.23); 6-phospho-beta-galactosidase (EC 3.2.1.85); 6-phospho-beta- ... glucosidase (EC 3.2.1.86); lactase-phlorizin hydrolase (EC 3.2.1.62), lactase (EC 3.2.1.108); beta-mannosidase (EC 3.2.1.25); ... myrosinase (EC 3.2.1.147). 6-phospho-beta-galactosidase InterPro: IPR005928 GBA3; KL; KLB; LCT; LCTL; GH1 in CAZypedia ...

https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_1

... produces beta-glucosidase. Parte, A.C. "Dyella". LPSN. "Dyella koreensis". www.uniprot.org. Parker, Charles ... nov., a beta-glucosidase-producing bacterium". International Journal of Systematic and Evolutionary Microbiology. 55 (Pt 4): ...

https://en.wikipedia.org/wiki/Dyella_koreensis

... beta-glucosidase (EC 3.2.1.21); beta-xylosidase (EC 3.2.1.37); N-acetyl beta-glucosaminidase (EC 3.2.1.52); glucan beta-1,3- ... Varghese JN, Hrmova M, Fincher GB (February 1999). "Three-dimensional structure of a barley beta-D-glucan exohydrolase, a ... glucosidase (EC 3.2.1.58); cellodextrinase (EC 3.2.1.74); exo-1,3-1,4-glucanase (EC 3.2.1). These enzymes are two-domain ...

https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_3

nov., a beta-glucosidase-producing bacterium in the family Sphingomonadaceae in the alpha-4 subgroup of the Proteobacteria". ... nov., a beta-glucosidase-producing bacterium in the family Sphingomonadaceae in the alpha-4 subgroup of the Proteobacteria". ... Sphingomonas soli produces beta-glucosidase. LPSN lpsn.dsmz.de Straininfo of Sphingomonas soli UniProt Deutsche Sammlung von ...

https://en.wikipedia.org/wiki/Sphingomonas_soli

"Entrez Gene: GBA glucosidase, beta; acid (includes glucosylceramidase)". Deegan PB, Cox TM (2012). "Imiglucerase in the ... acid β-glucosidase (bile acid), also EC 3.2.1.45 GBA3: acid β-glucosidase (cytosolic), EC 3.2.1.21 ENSG00000177628 GRCh38: ... Lieberman RL (2011). "A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C". Enzyme ... β-Glucocerebrosidase (also called acid β-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, or GCase) is an enzyme with ...

https://en.wikipedia.org/wiki/Glucocerebrosidase

nov., a beta-glucosidase-producing bacterium". Int J Syst Evol Microbiol. 59 (Pt 9): 2191-4. doi:10.1099/ijs.0.008300-0. PMID ... Castellaniella ginsengisoli is a Gram-negative, oxidase- and catalase-positive, rod-shaped, motile, beta-glucosidase-producing ...

https://en.wikipedia.org/wiki/Castellaniella_ginsengisoli

Weber JP, Fink AL (October 1980). "Temperature-dependent change in the rate-limiting step of beta-glucosidase catalysis". The ... Glycoside hydrolysis by lysozyme and beta-glucosidase". Biochemistry. 8 (10): 4214-21. doi:10.1021/bi00838a045. PMID 5388150. ... Glycoside hydrolysis by lysozyme and beta-glucosidase". Biochemistry. 8 (10): 4214-21. doi:10.1021/bi00838a045. PMID 5388150. ... Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl- ...

https://en.wikipedia.org/wiki/Lysozyme

6-phospho-beta-glucosidase (EC 3.2.1.86); 6-phospho-alpha-glucosidase (EC 3.2.1.122); alpha-galactosidase (EC 3.2.1.22). 6- ... phospho-alpha-glucosidase requires both NAD(H) and divalent metal (Mn2+, Fe2+, Co2+, or Ni2+) for activity. GH4 in CAZypedia ... dependent 6-phospho-alpha-glucosidase. Assignment to family 4 of the glycosylhydrolase superfamily". The Journal of Biological ...

https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_4

y[ _]9 Glycoside hydrolase family 17 CAZY GH_17 comprises enzymes with several known activities; endo-1,3-beta-glucosidase (EC ...

https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_17

Beta glucosidase activity is regulated via circadian rhythms. Fluorescence studies have shown that the binding sites of leaf ... which is inactivated by hydrolysis of the glycosidic bond via beta glucosidase. In Lespedeza cuneata the leaf opening factor, ...

https://en.wikipedia.org/wiki/Nyctinasty

as the fungus produces a potent beta-glucosidase. trans-Piceid is the glucoside formed with trans-resveratrol, while cis-piceid ... "Purification and characterization of piceid-β-d-glucosidase from Aspergillus oryzae". Process Biochemistry. 42: 83-88. doi: ...

https://en.wikipedia.org/wiki/Piceid

Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme ... Cytosolic beta-glucosidase is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside ... 2010). "The cytosolic beta-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation". Blood Cells Mol. Dis. 46 ... Beutler E, Beutler L, West C (2004). "Mutations in the gene encoding cytosolic beta-glucosidase in Gaucher disease". J. Lab. ...

https://en.wikipedia.org/wiki/GBA3

"Trifolium repens mRNA for non-cyanogenic beta-glucosidase - Nucleotide - NCBI". Ncbi.nlm.nih.gov. Retrieved 2019-06-29. ...

https://en.wikipedia.org/wiki/International_Nucleotide_Sequence_Database_Collaboration

... phloridzin beta-glucosidase, lactase-phlorizin hydrolase, and phloridzin glucosidase. Leese HJ, Semenza G (1973). "On the ... Malathi P, Crane RK (1969). "Phlorizin hydrolase: a beta-glucosidase of hamster intestinal brush border membrane". Biochim. ... Other names in common use include phlorizin hydrolase, phloretin-glucosidase, glycosyl ceramide glycosylhydrolase, ...

https://en.wikipedia.org/wiki/Glycosylceramidase

"Screening of carbon sources for beta-glucosidase production by Aspergillus saccharolyticus". International Biodeterioration & ...

https://en.wikipedia.org/wiki/Aspergillus_saccharolyticus

Chinchetru MA, Cabezas JA, Calvo P (1989). "Purification and characterization of a broad specificity beta-glucosidase from ... beta-xylosidase, exo-1,4-beta-xylosidase, beta-D-xylopyranosidase, exo-1,4-xylosidase, exo-1,4-beta-D-xylosidase, 1,4-beta-D- ... Xylan+1,4-beta-xylosidase at the US National Library of Medicine Medical Subject Headings (MeSH) Biology portal. ... This enzyme catalyses the following chemical reaction Hydrolysis of (1->4)-beta-D-xylans, to remove successive D-xylose ...

https://en.wikipedia.org/wiki/Xylan_1,4-b-xylosidase

nov., with Beta-Glucosidase Activity Isolated from Soil of a Ginseng Field". Current Microbiology. 74 (12): 1417-1424. doi: ...

https://en.wikipedia.org/wiki/Chryseobacterium_ginsengiterrae

... is a potent irreversible inhibitor of beta-glucosidases. It is a cyclitol mimic of beta-glucose with an epoxide ... Gloster, T. M., Madsen, R. and Davies, G. J. (2007) 'Structural basis for cyclophellitol inhibition of a β-glucosidase', ... 1990) 'Production, isolation and structure determination of a novel β-glucosidase Inhibitor, cyclophellitol, from phellinus sp ...

https://en.wikipedia.org/wiki/Cyclophellitol

... may refer to: Gelatinase biosynthesis-activating pheromone, a bacterial peptide Glucosidase, beta; acid, pseudogene, a ...

https://en.wikipedia.org/wiki/GBAP

nov., a beta-glucosidase-producing bacterium isolated from soil of a ginseng field". International Journal of Systematic and ...

https://en.wikipedia.org/wiki/Microbacterium_ginsengisoli

Li, Dan (May 2013). "Characterization and application of an acidophilic and thermostable beta-glucosidase from Thermofilum ...

https://en.wikipedia.org/wiki/Thermofilum

"Cuckoo fungus mimics termite eggs by producing the cellulose-digesting enzyme beta-glucosidase". Current Biology. 19 (1): 30-6 ...

https://en.wikipedia.org/wiki/Fibularhizoctonia

Different mutations in the GBA (beta-glucosidase) gene determine the remaining activity of the enzyme. In type I, there is some ... Numerous different mutations occur; sequencing of the beta-glucosidase gene is sometimes necessary to confirm the diagnosis. ... also known as beta-glucosidase, EC 3.2.1.45, PDB: 1OGS) on the first chromosome (1q22). The enzyme is a 55.6-kilodalton, 497- ... the origins of the Ashkenazi Jewish N370S and 84GG acid beta-glucosidase mutations". American Journal of Human Genetics. 66 (6 ...

https://en.wikipedia.org/wiki/Gaucher's_disease

nov., a beta-glucosidase-producing bacterium isolated from soil of a ginseng field". Int. J. Syst. Evol. Microbiol. 56 (Pt 11 ... Paraburkholderia ginsengisoli has the ability to produce β-glucosidase. Sawana A, Adeolu M, Gupta RS. (2014). "Molecular ...

https://en.wikipedia.org/wiki/Paraburkholderia_ginsengisoli

... , or beta-D-glucosidase (EC 3.2.1.21), is an enzyme found in many plants including cassava and the butter bean. In ... "Purification and properties of beta-D-glucosidase (linamarase) from the butter bean, Phaseolus lunatus". Last accessed 13 ...

https://en.wikipedia.org/wiki/Linamarase

These enzymes include amygdalin beta-glucosidase, prunasin beta-glucosidase and mandelonitrile lyase. In contrast, although the ...

https://en.wikipedia.org/wiki/Prunus_serotina

These lipids are then hydrolyzed by beta-glucosidases and beta-galactosidases to regenerate ceramide. Similarly, sphingomyelin ...

https://en.wikipedia.org/wiki/Sphingolipid

Production of beta-glucosidases is well known in members of the genus Aspergillus; however, only a few species can produce ... Beta-glucosidases produced by A. unguis are characteristically highly glucose-tolerant. For this reason, the fungus has been ... "Highly glucose tolerant β-glucosidase from Aspergillus unguis: NII 08123 for enhanced hydrolysis of biomass". Journal of ...

https://en.wikipedia.org/wiki/Aspergillus_unguis

The enzyme vicianin beta-glucosidase uses (R)-vicianin and water to produce mandelonitrile and vicianose. The fruits of ...

https://en.wikipedia.org/wiki/Vicianose

In competitive inhibition, an inhibitor that resembles the normal substrate binds to the enzyme, usually at the active site, and prevents the substrate from binding.[8] At any given moment, the enzyme may be bound to the inhibitor, the substrate, or neither, but it cannot bind both at the same time. During competitive inhibition, the inhibitor and substrate compete for the active site. The active site is a region on an enzyme which a particular protein or substrate can bind to. The active site will only allow one of the two complexes to bind to the site therefore either allowing for a reaction to occur or yielding it. In competitive inhibition the inhibitor resembles the substrate therefore taking its place and binding to the active site of an enzyme. Increasing the substrate concentration would diminish the "competition" for the substrate to properly bind to the active site and allow a reaction to occur.[3] When the substrate is of higher concentration than that of the competitive inhibitor, it ...

https://en.wikipedia.org/wiki/Competitive_inhibition

These enzymes include amygdalin beta-glucosidase, prunasin beta-glucosidase and mandelonitrile lyase.[22] In contrast, although ...

https://en.m.wikipedia.org/wiki/Prunus_serotina

Jul 1994). "The design of potential antidiabetic drugs: experimental investigation of a number of beta-D-glucose analogue ... α1-6 glucosidase enzyme is required to break the remaining (single glucose) α1-6 residue that remains in the new linear chain. ...

https://en.wikipedia.org/wiki/Glycogen_phosphorylase

... , also called α-1,4-glucosidase[5] and acid maltase,[6] is an enzyme (EC 3.2.1.20) that helps to break ... alpha-1,4-glucosidase activity. • alpha-glucosidase activity. Cellular component. • membrane. • lysosomal membrane. • lysosomal ... maltose alpha-glucosidase activity. • catalytic activity. • hydrolase activity. • carbohydrate binding. • isomaltase. • ... This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. ...

https://en.wikipedia.org/wiki/Acid_alpha-glucosidase

... aryl-beta-glucosidase, beta-D-glucosidase, beta-glucoside glucohydrolase, arbutinase, amygdalinase, p-nitrophenyl beta- ... Beta-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in beta-D-glucosides and ... Vicianin beta-glucosidase. References[edit]. *^ PDB: 3AHX; Jeng WY, Wang NC, Lin MH, Lin CT, Liaw YC, Chang WJ, Liu CI, Liang ... glucosidase, primeverosidase, amygdalase, linamarase, salicilinase, and beta-1,6-glucosidase. Cellulose is a polymer composed ...

https://en.wikipedia.org/wiki/Beta-glucosidase

Separation and characterization of cellulases and beta-glucosidases". The Biochemical Journal. 177 (1): 9-19. doi:10.1042/ ... beta-1,4-glucanase, beta-1,4-endoglucan hydrolase, endoglucanase D, 1,4-(1,3,1,4)-beta-D-glucan 4-glucanohydrolase), ... Cellobiases (EC 3.2.1.21) or beta-glucosidases hydrolyse the exocellulase product into individual monosaccharides. ... and a beta-glucosidase (76,000 daltons).[14] Numerous "signature" sequences known as dockerins and cohesins have been ...

https://en.wikipedia.org/wiki/Cellulase

Additionally, some strains of the bacterium have beta-glucosidase enzymes that can break down monoglucosides which are aroma ...

https://en.m.wikipedia.org/wiki/Malolactic_fermentation

"Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-beta-glucosidase mutant that causes Gaucher ... Ding, F; JM Borreguero; SV Buldyrey; HE Stanley; NV Dokholyan (2003). "Mechanism for the alpha-helix to beta-hairpin transition ...

https://en.m.wikipedia.org/wiki/Molecular_dynamics

... is first hydrolyzed to cellobiose by cellulase and then cellobiose is further hydrolyzed to glucose by beta-glucosidase. ...

https://en.m.wikipedia.org/wiki/Hydrolysation

EC 3.2.1.48 is sucrose alpha-glucosidase. Physiology[edit]. Sucrose intolerance (also known as congenital sucrase-isomaltase ... Glucosidases. *Cellulase. *Alpha-glucosidase *Acid. *Neutral AB. *Neutral C. *Beta-glucosidase *cytosolic ...

https://en.wikipedia.org/wiki/Sucrase

Amygdalin beta-glucosidase is an enzyme that uses (R)-amygdalin and H2O to produce (R)-prunasin and D-glucose. ... Prunasin beta-glucosidase is an enzyme that uses (R)-prunasin and H2O to produce D-glucose and mandelonitrile. ...

https://en.m.wikipedia.org/wiki/Prunasin

... distribution of cellulases and properties of endo-beta-1,4-glucanase.. Zoological Science. 1997, 14 (1): 83-93. PMID 9200983. ... Cuckoo fungus mimics termite eggs by producing the cellulose-digesting enzyme β-glucosidase. Current Biology. 2009, 19 (1): 30- ...

https://zh.wikipedia.org/wiki/白蟻

Thus glucosidases catalyze the hydrolysis of glucosides and xylanases catalyze the cleavage of the xylose based homopolymer ... One of the important occurrences of glycoside hydrolases in bacteria is the enzyme beta-galactosidase (LacZ), which is involved ...

https://en.m.wikipedia.org/wiki/Glycoside_hydrolase

Effects of iridoids on lipoxygenase and hyaluronidase activities and their activation by beta-glucosidase in the presence of ... West, B.J.. Hepatotoxicity from interferon-beta, not Noni juice.. „Digestion". 74, s. 47-48, 2006. PMID: 17068398. ... Walther, EU; Hohlfeld, R. Multiple sclerosis: side effects of interferon beta therapy and their management.. „Neurology". 53 (8 ... Była ona leczona interferonem-beta, przy którym potwierdzony jest fakt występowania efektów ubocznych, w tym hepatotoksyczności ...

https://pl.wikipedia.org/wiki/Morwa_indyjska

The diagnosis of the adult type of Gaucher's disease and its carrier state by demonstration of deficiency of beta-glucosidase ... Studies on human beta-D-N-acetylhexosaminidases. III. Biochemical genetics of Tay-Sachs and Sandhoff's diseases. J Biol Chem ... Chemical chaperones increase the cellular activity of N370S b-glucosidase: A therapeutic strategy for Gaucher's disease. Proc ...

https://en.wikipedia.org/wiki/Ernest_Beutler

The COX-2 enzyme was discovered in 1988 by Daniel Simmons, a Brigham Young University researcher.[23] The mouse COX-2 gene was cloned by UCLA scientist Dr. Harvey Herschman, a finding published in 1991.[24]. The basic research leading to the discovery of COX-2 inhibitors has been the subject of at least two lawsuits. Brigham Young University has sued Pfizer, alleging breach of contract from relations BYU had with the company at the time of Dr. Simmons's work.[25][26] A settlement was reached in April 2012 in which Pfizer agreed to pay $450 million.[27][28] The other litigation is based on United States Pat. No. 6,048,850[29] owned by University of Rochester, which claimed a method to treat pain without causing gastro-intestinal distress by selectively inhibiting COX-2. When the patent issued, the university sued Searle (later Pfizer) in a case called, University of Rochester v. G.D. Searle & Co., 358 F.3d 916 (Fed. Cir. 2004). The court ruled in favor of Searle in 2004, holding in essence that ...

https://en.wikipedia.org/wiki/COX_inhibitor

Beta blockers (e.g., alprenolol, carteolol, cyanopindolol, iodocyanopindolol, isamoltane, oxprenolol, penbutolol, pindobind, ... agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the α2-adrenergic receptors in beta ...

https://en.wikipedia.org/wiki/Bromocriptine

... a lineage of iso-maltose glucosidases and a lineage that further split into maltose glucosidases and iso-maltose glucosidases. ... beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily". Biochemistry. 42 (28 ... In light of the large number of paralogous fungal α-glucosidase genes with a number of specific maltose-like (maltose, turanose ... Antithetically, the ancestor before the latter split had a more pronounced isomaltose-like glucosidase activity.[4] ...

https://en.wikipedia.org/wiki/Enzyme_promiscuity

A 2017 population-based, matched-cohort study of 93,197 men aged 66 years and older with BPH found that finasteride and dutasteride were associated with a significantly increased risk of depression (HR, 1.94; 95% CI, 1.73-2.16) and self-harm (HR, 1.88; 95% CI, 1.34-2.64) during the first 18 months of treatment, but were not associated with an increased risk of suicide (HR, 0.88; 95% CI, 0.53-1.45).[31][32][33][21] After the initial 18 months of therapy, the risk of self-harm was no longer heightened, whereas the elevation in risk of depression lessened but remained marginally increased (HR, 1.22; 95% CI, 1.08-1.37).[31][32][21] The absolute increase in the rate of depression was 247 per 100,000 patient-years and of self-harm was 17 per 100,000 patient-years.[21][34] As such, on the basis of these findings, it has been stated that cases of depression in patients that are attributable to 5-ARIs will be encountered on occasion, while cases of self-harm attributable to 5-ARIs will be encountered ...

https://en.wikipedia.org/wiki/5α-Reductase_inhibitor

Two important sugar crops predominate: sugarcane (Saccharum spp.) and sugar beets (Beta vulgaris), in which sugar can account ...

https://en.wikipedia.org/wiki/Sucrose

Dworkin, Martin; Falkow, Stanley (2006). The Prokaryotes: Proteobacteria: alpha and beta subclasses. Springer. p. 169. ISBN ... β-glucosidase, β-xylosidase, or polygalacturonase, which Saccharomyces yeast may not produce.[68] ...

https://en.m.wikipedia.org/wiki/Cider

The affinity of RI for ribonucleases is among the highest for any protein-protein interaction; the dissociation constant of the RI-RNase A complex is in the femtomolar (fM) range under physiological conditions while that for the RI-angiogenin complex is less than 1 fM. Despite this high affinity, RI is able to bind a wide variety of RNases A despite their relatively low sequence identity. Both biochemical studies and crystallographic structures of RI-RNase A complexes suggest that the interaction is governed largely by electrostatic interactions, but also involves substantial buried surface area.[3][4] RI's affinity for ribonucleases is important, since many ribonucleases have cytotoxic and cytostatic effects that correlate well with ability to bind RI.[5] Mammalian RIs are unable to bind certain pancreatic ribonuclease family members from other species. In particular, amphibian RNases, such ranpirnase and amphinase from the Northern leopard frog, escape mammalian RI and have been noted to have ...

https://en.wikipedia.org/wiki/Ribonuclease_inhibitor

Beyond being a catalyst in the rate-limiting step in testosterone reduction, 5α-reductase isoforms I and II reduce progesterone to 5α-dihydroprogesterone (5α-DHP) and deoxycorticosterone to dihydrodeoxycorticosterone (DHDOC). In vitro and animal models suggest subsequent 3α-reduction of DHT, 5α-DHP and DHDOC lead to neurosteroid metabolites with effect on cerebral function. These neurosteroids, which include allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol, act as potent positive allosteric modulators of GABAA receptors, and have antidepressant, anxiolytic, prosexual, and anticonvulsant effects.[33] 5α-Dihydrocortisol is present in the aqueous humor of the eye, is synthesized in the lens, and might help make the aqueous humor itself.[34] 5α-Dihydroaldosterone is a potent antinatriuretic agent, although different from aldosterone. Its formation in the kidney is enhanced by restriction of dietary salt, suggesting it may help retain sodium.[35] 5α-DHP is a ...

https://en.wikipedia.org/wiki/5-alpha-reductase_inhibitor

Vicianinska beta-glukozidaza (EC 3.2.1.119, vicijaninska hidrolaza) je enzim sa sistematskim imenom (R)-vicijanin beta-D- ... Преузето из „https://sr.wikipedia.org/w/index.php?title=Vicianinska_beta-glukozidaza&oldid=15686363" ...

https://sr.wikipedia.org/wiki/Vicianinska_beta-glukozidaza

Chiba S (august 1997). "Molecular mechanism in alpha-glucosidase and glucoamylase". Biosci. Biotechnol. Biochem. 61 (8): 1233-9 ... Monomerni protein sadrži centraln domen u kojem je osam paralelnih beta-lanaca okružeo sa osam paralelnih alfa niti. Unutar ove ... Yamamoto E, Makino Y, Omichi K (maj 2007). "Active site mapping of amylo-alpha-1,6-glucosidase in porcine liver glycogen ... Gillard BK, White RC, Zingaro RA, Nelson TE (septembar 1980). "Amylo-1,6-glucosidase/4-alpha-glucanotransferase. Reaction of ...

https://bs.wikipedia.org/wiki/Enzim_razgradnje_glikogenskih_grana

"Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective". Journal of ...

https://en.wikipedia.org/wiki/Statin

When used in the central nervous system to alleviate neurological symptoms, such as rivastigmine in Alzheimer's disease, all cholinesterase inhibitors require doses to be increased gradually over several weeks, and this is usually referred to as the titration phase. Many other types drug treatments may require a titration or stepping up phase. This strategy is used to build tolerance to adverse events or to reach a desired clinical effect.[12] This also prevents accidental overdose and is therefore recommended when initiating treatment with drugs that are extremely potent and/or toxic (drugs with a low therapeutic index). ...

https://en.wikipedia.org/wiki/Acetylcholinesterase_inhibitors

Glucosidases. *Cellulase. *Alpha-glucosidase *Acid. *Neutral AB. *Neutral C. *Beta-glucosidase *cytosolic ...

https://en.wikipedia.org/wiki/Neuraminidase

... steryl-beta-glucosidase activity, cholesterol allpha-glucosyltransferase activity ...

https://cy.m.wikipedia.org/wiki/Cholesterol

In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin,[21][22] the United States FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer. In a joint letter to the New England Journal of Medicine, the agencies stated that they had not yet reached a final conclusion regarding a possible causative relationship.[23]. A 2014 meta-analysis found no evidence for increased pancreatic cancer risk in people treated with DPP-4 inhibitors, but owing to the modest amount of data available, was not able to completely exclude possible risk.[24]. ...

https://en.wikipedia.org/wiki/DPP4_inhibitor

... aryl-beta-glucosidase, beta-D-glucosidase, beta-glucoside glucohydrolase, arbutinase, amygdalinase, p-nitrophenyl beta- ... glucosidase, primeverosidase, amygdalase, linamarase, salicilinase, and beta-1,6-glucosidase. Amygdalin beta-glucosidase ... a related enzyme Prunasin beta-glucosidase Vicianin beta-glucosidase PDB: 3AHX; Jeng WY, Wang NC, Lin MH, Lin CT, Liaw YC, ... Beta-glucosidase is an enzyme that catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in beta-D ...

https://en.wikipedia.org/wiki/Beta-glucosidase

In enzymology, a prunasin beta-glucosidase (EC 3.2.1.118) is an enzyme that catalyzes the chemical reaction (R)-prunasin + H2O ... The systematic name of this enzyme class is prunasin beta-D-glucohydrolase. This enzyme is also called prunasin hydrolase. ...

https://en.wikipedia.org/wiki/Prunasin_beta-glucosidase

beta-glucosidase [Xanthomonas gardneri] beta-glucosidase [Xanthomonas gardneri]. gi,1120833987,gnl,PRJNA344031,BI317 0,gb, ...

https://www.ncbi.nlm.nih.gov/protein/APP83321

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

http://www.ebi.ac.uk/interpro/protein/A1DCV5

6-phospho-beta-glucosidase [Escherichia coli W]. * This record was replaced or removed. The sequence YP_006173076 is 100% ...

https://www.ncbi.nlm.nih.gov/protein/386709355

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. UniProt ...

http://www.rcsb.org/pdb/protein/P22505

Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and ... The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase, or beta-glucosidase ... Polypeptides having beta-glucosidase activity and polynucleotides encoding same. Title: Polypeptides having beta-glucosidase ... The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta- ...

https://www.osti.gov/doepatents/biblio/1117660

Crystal structure of beta-glucosidase A from Bacillus polymyxa: insights into the catalytic activity in family 1 glycosyl ...

http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1BGA

Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. ... "Substrate (aglycone) specificity of human cytosolic beta-glucosidase.". Berrin J.-G., Czjzek M., Kroon P.A., McLauchlan W.R., ... "Substrate (aglycone) specificity of human cytosolic beta-glucosidase.". Berrin J.-G., Czjzek M., Kroon P.A., McLauchlan W.R., ... "Substrate (aglycone) specificity of human cytosolic beta-glucosidase.". Berrin J.-G., Czjzek M., Kroon P.A., McLauchlan W.R., ...

https://www.uniprot.org/uniprot/Q9H227

Shop a large selection of MP Biomedicals beta-Glucosidase from Sweet Almonds products and learn more about MP Biomedicals beta- ... beta-Glucosidase. For Use With (Application). Potential applications in pharmaceutical, cosmetic and detergent industries, ...

https://www.fishersci.com/shop/products/mp-biomedicals-beta-glucosidase-sweet-almonds-3/p-4605322

... methyl-beta-glucoside-6P and p-nitrophenyl-beta-D-glucopyranoside-6P. Is also able to hydrolyze phospho-N,N-diacetylchitobiose ... Hydrolyzes a wide variety of P-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, gentiobiose-6P, ... 6-phospho-beta-glucosidaseAdd BLAST. 449. Proteomic databases. PaxDb, a database of protein abundance averages across all three ... 6-phospho-beta-glucosidase activity Source: EcoCyc ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for the ...

https://www.uniprot.org/uniprot/P17411

Acid beta-Glucosidase Deficiencies. An autosomal recessive disorder caused by a deficiency of Acid beta-Glucosidase ( ...

http://www.online-medical-dictionary.org/definitions-a/acid-beta-glucosidase-deficiencies.html

Similar Discussions: Immobilization of Beta-glucosidase with glutaraldehyde * Vitamin A and Beta Carotene (Replies: 1) ... I want to immobilize beta-glucosidase (on Sepabeads with an amine group). The problem I have is I dont have a strong chemical/ ... Can the Beta carbons of ketones act as nucleophiles? And one more question. (Replies: 3) ... Barium Borate- beta BBO crystals (what am I looking at?) (Replies: 3) ...

https://www.physicsforums.com/threads/immobilization-of-beta-glucosidase-with-glutaraldehyde.826481/

View Human Cytosolic beta-Glucosidase/GBA3 Antibody (AF5969) datasheet. Validated in IP, WB ... Cytosolic beta-Glucosidase; Cytosolic beta-glucosidase-like protein 1; EC 3.2.1.21; GBA3; GLUC; glucosidase, beta, acid 3 ( ... There are three beta-glucosidases (GBA) in human genome. GBA1 endodes a lysosomal membrane protein that cleaves the beta- ... GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides. GBA3 is a cytosolic beta- ...

https://www.rndsystems.com/products/human-cytosolic-beta-glucosidase-gba3-antibody_af5969

IC50 values are 1 and 100 μM for β-glucosidase and α-glucosidase respectively). Upregulates CD1d expression by THP-1 cells… ... Selective, irreversible β-glucosidase inhibitor (IC50 values are 1 and 100 μM for β-glucosidase and α-glucosidase respectively ...

https://www.abcam.com/conduritol-b-epoxide-conduritol-epoxide-beta-glucosidase-inhibitor-ab144118.html

An efficient beta-glucosidase facilitates hydrolysis at specified process conditions, and key points to consider in this ... In this review, we discuss the important role beta-glucosidases play in complex biomass hydrolysis and how they create a ... Among the cellulose degrading enzymes, beta-glucosidases are essential for efficient hydrolysis of cellulosic biomass as they ... alternatives to the currently available enzyme preparations either by improving known or screening for new beta-glucosidases. ...

http://www.mdpi.com/2218-273X/3/3/612

Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the ... ACID-BETA-GLUCOSIDASE WITH N-BUTYL-DEOXYNOJIRIMYCIN (2v3d). (see also Treatment of Gaucher disease) ... Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the ... Gaucher disease is caused by mutations in the gene encoding acid beta-glucosidase (GlcCerase), resulting in glucosylceramide ( ...

http://proteopedia.org/wiki/index.php/Acid_beta-glucosidase_with_N-butyl-deoxynojirimycin

furostanol glycoside 26-O-beta-glucosidase: from Costus speciosus rhizomes; specifically cleaves the C-26-bound glucose moiety ... Glucosidases: 578*Cellulases: 33*beta-Glucosidase: 195*furostanol glycoside 26-O-beta-glucosidase ... furostanol glycoside 26-O-beta-glucosidase. Subscribe to New Research on furostanol glycoside 26-O-beta-glucosidase ...

http://www.curehunter.com/public/keywordSummaryC097713-furostanol-glycoside-26-O-beta-glucosidase.do

A digestive beta-glucosidase from the silkworm, Bombyx mori: cDNA cloning, expression and enzymatic characterization. Download ... A digestive beta-glucosidase cDNA was cloned from the silkworm, Bombyx mori. The B. mori beta-glucosidase cDNA contains an open ... VL - 141 IS - 4 N2 - A digestive beta-glucosidase cDNA was cloned from the silkworm, Bombyx mori. The B. mori beta-glucosidase ... mori beta-glucosidase to be a single gene. Northern blot analysis of B. mori beta-glucosidase gene confirmed larval midgut- ...

https://www.unboundmedicine.com/medline/citation/15970451/A_digestive_beta_glucosidase_from_the_silkworm_Bombyx_mori:_cDNA_cloning_expression_and_enzymatic_characterization_

... *. ...

https://medworm.com/810923766/deletion-of-bglc-triggers-a-genetic-compensation-response-by-awakening-the-expression-of-alternative/

Competitive Inhibition constant on almonds beta Glucosidase; LI=Limited inhibition. ...

https://pubchem.ncbi.nlm.nih.gov/bioassay/220893

A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was purified to homogeneity after cultivation on a cellulose and ... A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was purified to homogeneity after cultivation on a cellulose and ... Characterization and kinetic analysis of a thermostable GH3 beta-glucosidase from Penicillium brasilianum. Krogh, Kristian B. R ... article{bf417611-2d38-438f-96a9-4ab1a291f9a9, abstract = {A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was ...

https://lup.lub.lu.se/search/publication/1568986

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed ...

http://specialtylabs.com/tests/details.asp?id=38195

Compared with free beta-glucosidase, the immobilized enzyme exhibited: (i) a similar pH optimum but more activity at lower pH ... beta-Glucosidase of Aspergillus phoenicis QM 329 was immobilized on chitosan, using the bifunctional agent glutaraldehyde. The ... Compared with free beta-glucosidase, the immobilized enzyme exhibited: (i) a similar pH optimum but more activity at lower pH ... beta-Glucosidase of Aspergillus phoenicis QM 329 was immobilized on chitosan, using the bifunctional agent glutaraldehyde. The ...

https://www.semanticscholar.org/paper/Immobilization-of-Aspergillus-beta-glucosidase-on-Bissett-Sternberg/49ac41c1a343f7775cec6e0430f96dfa91d10c62

beta-Glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1. Rodjana OPASSIRI, Yanling HUA, ... beta-Glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1 ... beta-Glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1 ... beta-Glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1 ...

http://www.biochemj.org/content/379/1/125

The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.

http://techportal.eere.energy.gov/patent.do/ID=32902

For specimen collection and processing instructions, refer to the Genetics Laboratory Test Directory for Beta-Glucosidase at: ...

https://www.calgarylabservices.com/lab-services-guide/lab-tests/AlphabeticalListing/B/Beta-Glucosidase.aspx

The E358S mutant of Agrobacterium sp beta-glucosidase is a greatly improved glycosynthase. ... The E358S mutant of Agrobacterium sp beta-glucosidase is a greatly improved glycosynthase. ... The E358S mutant of Agrobacterium sp beta-glucosidase is a greatly improved glycosynthase ... beta-glucosidase (Abg) by mutating the nucleophile glutamate to alanine (E358A), synthesizes oligosaccharides in yields ...

https://www.chem.ubc.ca/node/16954

Effect of differently post-treated dewatered sewage sludge on beta-glucosidase activity, microbial biomass carbon, basal ... Effect of differently post-treated dewatered sewage sludge on beta-glucosidase activity, microbial biomass carbon, basal ... "Effect of differently post-treated dewatered sewage sludge on beta-glucosidase activity, microbial biomass carbon, basal ...

https://upcommons.upc.edu/handle/2117/2580?show=full

Tiessen, Axel 2011-06-22 00:00:00 The hydrolysis of beta-d-glucosidic bonds which is required for the liberation of many physiologically important compounds is catalyzed by the enzyme beta-glucosidase (BGLU, EC 3.2.1.21). (deepdyve.com)
and (iv) β-glucosidase (EC 3.2.1.21, BGL). (frontiersin.org)
A beta-glucosidase (EC 3.2.1.21) was purified to homogeneity from cell-free extracts of an extremely thermophilic anaerobic bacterium. (waikato.ac.nz)
Cellobiases (EC 3.2.1.21) or beta-glucosidases hydrolyse the exocellulase product into individual monosaccharides. (wikipedia.org)

Beta-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in beta-D-glucosides and oligosaccharides, with release of glucose. (wikipedia.org)
Beta-glucosidase is also capable of hydrolysis on small oligomers that are produced by other enzymes without the assistance of an intermediate enzyme. (wikipedia.org)
Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. (rcsb.org)
GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides. (rndsystems.com)
Among the cellulose degrading enzymes, beta-glucosidases are essential for efficient hydrolysis of cellulosic biomass as they relieve the inhibition of the cellobiohydrolases and endoglucanases by reducing cellobiose accumulation. (mdpi.com)
In this review, we discuss the important role beta-glucosidases play in complex biomass hydrolysis and how they create a bottleneck in industrial use of lignocellulosic materials. (mdpi.com)
An efficient beta-glucosidase facilitates hydrolysis at specified process conditions, and key points to consider in this respect are hydrolysis rate, inhibitors, and stability. (mdpi.com)
Almond beta-glucosidase was used to catalyze the transglycosylation of p-nitrophenyl-beta-D-glucoside to alkyl glucosides, with hydrolysis to glucose as a side reaction. (lu.se)
The recombinant Beta -glucosidase catalyses the hydrolysis of cellobiose and salicin. (ccsenet.org)
the hydrolysis of glycosidic terpenes by Ap-beta-gl was studied, and its ability to efficiently release free terpenols was demonstrated by gas chromatography/mass spectrometry. (unifesp.br)
A new β-glucosidase enzyme which is tolerant to glucose and cellobiose, and which is effective for the hydrolysis of cellobiose to glucose, is disclosed. (google.com)
Within such scope, the present work aimed to evaluate the feasibility of entrapping beta-glucosidase in either sol gel or in Lentikats supports for application in cellobiose hydrolysis, and to perform the characterization of the resulting bioconversion systems. (unicamp.br)
Lentikats-entrapped glucosidase was used in 19 consecutive batch runs for cellobiose hydrolysis, without noticeable decrease in product yield. (unicamp.br)
The specific reaction involved is the hydrolysis of the 1,4-beta-D- glycosidic linkages in cellulose, hemicellulose , lichenin , and cereal beta-D-glucans . (wikipedia.org)

An autosomal recessive disorder caused by a deficiency of Acid beta-Glucosidase ( Glucosylceramidase ) leading to intralysosomal accumulation of glycosylceramide mainly in Cells of the Mononuclear Phagocyte System . (online-medical-dictionary.org)
Gaucher disease is caused by mutations in the gene encoding acid beta-glucosidase (GlcCerase), resulting in glucosylceramide (GlcCer) accumulation. (proteopedia.org)
Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease. (proteopedia.org)
of the native human acid β-glucosidase, expressed in cultured plant cells (pGlcCerase, 2v3f ) on those of N-butyl-deoxynojirimycin/pGlcCerase ( 2v3d ), N-nonyl-deoxynojirimycin/pGlcCerase ( 2v3e ), and isofagomine/deglycosylated Cerezyme (IFG/DG-Cerezyme, 2nsx ) reveals significant structural identity, neither of these ligands causes structural changes upon binding to the enzyme. (proteopedia.org)
The B. mori beta-glucosidase cDNA contains an open reading frame of 1473 bp encoding 491 amino acid residues. (unboundmedicine.com)
The B. mori beta-glucosidase possesses the amino acid residues involved in catalysis and substrate binding conserved in glycosyl hydrolase family 1. (unboundmedicine.com)
Global Markets Direct's, 'Glucosylceramidase (Acid Beta-Glucosidase or Alglucerase or D-Glucosyl-N-Acylsphingosine Glucohydrolase or EC 3.2.1.45) - Pipeline Review, H1 2016', provides in depth analysis on Glucosylceramidase (Acid Beta-Glucosidase or Alglucerase or D-Glucosyl-N-Acylsphingosine Glucohydrolase or EC 3.2.1.45) targeted pipeline therapeutics. (reportsnreports.com)
The report provides comprehensive information on the Glucosylceramidase (Acid Beta-Glucosidase or Alglucerase or D-Glucosyl-N-Acylsphingosine Glucohydrolase or EC 3.2.1.45), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. (reportsnreports.com)
Additionally, the report provides an overview of key players involved in Glucosylceramidase (Acid Beta-Glucosidase or Alglucerase or D-Glucosyl-N-Acylsphingosine Glucohydrolase or EC 3.2.1.45) targeted therapeutics development and features dormant and discontinued projects. (reportsnreports.com)
For more information, see Newborn Screening Act Sheet Gaucher Disease: Decreased Acid Beta-Glucosidase in Special Instructions. (testcatalog.org)
Gaucher disease is an autosomal recessive lysosomal storage disorder caused by reduced or absent acid beta-glucosidase (glucocerebrosidase) enzyme activity. (testcatalog.org)
Significantly reduced or absent enzyme activity of acid beta-glucosidase is diagnostic. (testcatalog.org)
Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by mutations in the glucosidase, beta, acid (GBA) gene that encodes the lysosomal enzyme glucosylceramidase (GCase). (pnas.org)
The first GCase-deficient mouse was created by insertion of the neomycin resistance gene into glucosidase, beta, acid (gba) exons 9 and 10 ( 17 ). (pnas.org)
The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. (justia.com)
The present invention relates to isolated bgl6 nucleic acid sequences which encode polypeptides having beta-glucosidase activity. (justia.com)

In the case of the Christmas Island red crab beta glucosidase not only produces glucose, but also removes cellobiose. (wikipedia.org)
In enzymology, a prunasin beta-glucosidase (EC 3.2.1.118) is an enzyme that catalyzes the chemical reaction (R)-prunasin + H2O ⇌ {\displaystyle \rightleftharpoons } D-glucose + mandelonitrile Thus, the two substrates of this enzyme are (R)-prunasin and H2O, whereas its two products are D-glucose and mandelonitrile. (wikipedia.org)
beta-Glucosidases are involved in the last step of the degradation of cellulosic biomass and hydrolyse the beta-glycosidic linkage between two adjacent molecules in dimers and oligomers of glucose. (diva-portal.org)
D-glucono-δ-Lactone + H2O2This enzyme is used for enzymatic determination of glucose, and for amylase-activity assay when coupled with α-glucosidase (AGH-201, AGH- 211, if maltooligosaccharide or modified starch is used as a. (sorachim.com)
β-glucosidases (BGLs) hydrolyze cello-oligosaccharides to glucose and play a crucial role in the enzymatic saccharification of cellulosic biomass. (frontiersin.org)
Inhibition of the beta-glucosidase by substrates and glucose is negligible. (waikato.ac.nz)
This β-glucosidase may be used in conjunction with cellulolytic enzymes for the treatment of cellulosic materials to convert cellulose to glucose. (google.com)
This invention relates to a β-glucosidase effective for hydrolyzing cellobiose to glucose, which has a high tolerance to glucose and cellobiose. (google.com)
Beta-glucocerebrosidase is a housekeeping enzyme that helps break down a large molecule called glucocerebroside into a sugar (glucose) and a simpler fat molecule (ceramide). (medlineplus.gov)
In this specific case, the glucose produced inhibits the action of beta-glucosidase. (eurekalert.org)
To increase saccharification efficiency, the beta-glucosidase has to be highly glucose tolerant. (eurekalert.org)
The formation of extracellular endo-1,4-beta-glucanases was induced by cellobiose and repressed by glucose. (helmholtz-hzi.de)
beta-Glucosidase activity was inhibited noncompetitively by glucose. (helmholtz-hzi.de)
Cellulases break down the cellulose molecule into monosaccharides ("simple sugars") such as beta- glucose , or shorter polysaccharides and oligosaccharides . (wikipedia.org)
Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide (PubMed:26724485). (genecards.org)
Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol (PubMed:24211208, PubMed:26724485). (genecards.org)
They hydrolyze terminal (1,4)alpha-glucosidic linkages and (1,6)beta-glucosidic linkages, liberating alpha-glucose and beta-glucose. (genecards.org)
Among the cellulolytic enzyme complex, β-glucosidase plays a key role and is the most critical that catalyze the final step in cellulose and hemicellulose into glucose [ 7 ]. (omicsonline.org)
Thus, β-glucosidases allow the cellulolytic enzymes to function more efficiently by producing glucose from cellobiose and reducing cellobiose inhibition [ 9 ]. (omicsonline.org)

instead, three-dimensional structural overlaps with other enzymes of known function suggested that SPy1599 contains a phosphate-binding pocket in the active site and has possible 6-phospho-beta-glycosidase activity. (ubc.ca)
Of these enzymes, β-glucosidase activity plays a relevant role in the transformation of the phenolic glycosides present in the olive fruit, generating different secoiridoid derivatives. (frontiersin.org)
The main goal of the present study was to characterize olive fruit β-glucosidase genes and enzymes responsible for the phenolic composition of virgin olive oil. (frontiersin.org)
Bacillus licheniformis was grown in minimal nutrient medium containing 1% (w/v) of distillers dried grain with soluble (DDGS), palm kernel meal (PKM), wheat bran (WB) or copra meal (CM), and the enzyme activity of endoglucanase, β-glucosidase, xylanase and reducing sugars was measured to investigate a possibility of using cost-effective agricultural residues in producing cellulolytic and hemicellulolytic enzymes. (ajas.info)
In the arsenal of necessary enzymes acting synergistically, beta-glucosidases are crucially important for their role in the last step of the cellulose saccharification cascade. (eurekalert.org)
beta-Glucosidases represent an important group of enzymes due to their pivotal role in various biotechnological processes. (unicamp.br)
Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. (genecards.org)
Cellulase is a family of at least 3 groups of enzymes, endo-(1, 4)-β-Dglucanase, exo-(1,4)-β-D-glucanase and β-glucosidases. (omicsonline.org)

In the case of beta-glucosidase, two carboxylate residues of glucosides, cellobiose, cellotriose, cellotetraose are involved at the active site. (wikipedia.org)
Hydrolyzes a wide variety of P-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, gentiobiose-6P, methyl-beta-glucoside-6P and p-nitrophenyl-beta-D-glucopyranoside-6P. (uniprot.org)
The B. mori beta-glucosidase cDNA was expressed as a 57-kDa polypeptide in baculovirus-infected insect Sf9 cells, and the recombinant beta-glucosidase was active on cellobiose and lactose, but not active on salicin, indicating that the B. mori beta-glucosidase possesses the characteristics of the Class 2 enzyme. (unboundmedicine.com)
The BGL had significant lower affinity for cellobiose compared with the artificial substrate para-nitrophenyl-beta-d-glucopyranoside (pNP-Glc) and further, pronounced substrate inhibition using pNP-Glc. (lu.se)
Lineweaver-Burk plots for p-nitrophenyl beta-glucoside, o-nitrophenyl beta-glucoside and cellobiose substrates are biphasic concave-downwards. (waikato.ac.nz)
Abeta- glucosidase gene bglB from Bacillus polymyxa 1.794 was cloned into the recombinant E. coli P81 and beta-glucosidase was expressed to give a new recombinant strain E. coli P81 (pUC19-bglB) with dual functions of cellobiose degradation and ethanol production . (bvsalud.org)
The exoglucanase/xylanase Cex from Cellulomonas fimi hydrolyzes beta-1,4-glycosidic bonds with net retention of anomeric configuration, releasing the disaccharides beta-cellobiose or beta-xylobiose. (nih.gov)
In the presence of sodium azide a new product, beta-cellobiosyl azide, is formed with these mutants whereas only cellobiose is formed with wild-type enzyme or the Glu127Asp mutant under similar conditions. (nih.gov)

GBA (Glucosylceramidase Beta) is a Protein Coding gene. (genecards.org)

The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase, or beta-glucosidase activity and isolated polynucleotides encoding polypeptides. (osti.gov)

Production of cellulase and beta-glucosidase activity during growth of the actinomycete Micromonospora chalcae on cellulose-containing media. (ulster.ac.uk)
Cellulase activity reached a maximum after 8 days and the beta-glucosidase activity was maximal within 16 to 18 days. (ulster.ac.uk)
Fingerprint Dive into the research topics of 'Production of cellulase and beta-glucosidase activity during growth of the actinomycete Micromonospora chalcae on cellulose-containing media. (ulster.ac.uk)

The bglu1 cDNA for a β-glucosidase cloned from rice ( Oryza sativa L.) seedlings was expressed as a soluble and active protein in Escherichia coli and designated BGlu1. (biochemj.org)
To be able to produce large amounts of enzyme, the beta-glucosidase coding gene from these isolates is cloned and transferred to bacteria that can grow fast and are easily controlled for their growth, such as Escherichia coli. (unair.ac.id)

The enzyme activity of the purified recombinant beta-glucosidase expressed in baculovirus-infected insect cells was approximately 665 U per microg of recombinant B. mori beta-glucosidase. (unboundmedicine.com)
The purified recombinant B. mori beta-glucosidase showed the highest activity at 35 degrees C and pH 6.0, and were stable at 50 degrees C at least for 10 min. (unboundmedicine.com)
Treatment of recombinant virus-infected Sf9 cells with tunicamycin, a specific inhibitor of N-glycosylation, revealed that the recombinant B. mori beta-glucosidase is N-glycosylated, but the carbohydrate moieties are not essential for enzyme activity. (unboundmedicine.com)
High purity recombinant β-Glucosidase ( Phanerochaete chrysosporium ) for use in research, biochemical enzyme assays and in vitro diagnostic analysis. (megazyme.com)
To achieve that, we have isolated an olive β-glucosidase gene from cultivar Picual ( OepGLU ), expressed in Nicotiana benthamiana leaves and purified its corresponding recombinant enzyme. (frontiersin.org)
Western blot analysis showed that recombinant OepGLU protein is detected by an antibody raised against the purified native olive mesocarp β-glucosidase enzyme, and exhibits a deduced molecular mass of 65.0 kDa. (frontiersin.org)

PDF] Immobilization of Aspergillus beta-glucosidase on chitosan. (semanticscholar.org)
beta-Glucosidase of Aspergillus phoenicis QM 329 was immobilized on chitosan, using the bifunctional agent glutaraldehyde. (semanticscholar.org)
A 2526 bp gene encoding Aspergillus niger Beta-glucosidase was chemically synthesized for its heterologous expression in methylotrophic yeast Pichia pastoris , using methanol as inducer. (ccsenet.org)

The GBA gene provides instructions for making an enzyme called beta-glucocerebrosidase. (medlineplus.gov)
It gets broken down by beta-glucocerebrosidase when cells die, and the components are reused as new cells are formed. (medlineplus.gov)
Most of the GBA gene mutations responsible for Gaucher disease change single protein building blocks (amino acids) in beta-glucocerebrosidase, altering the structure of the enzyme and preventing it from working normally. (medlineplus.gov)
Mutations in the GBA gene greatly reduce or eliminate the activity of beta-glucocerebrosidase in cells. (medlineplus.gov)
These mutations result in the production of an altered beta-glucocerebrosidase enzyme. (medlineplus.gov)

The systematic name of this enzyme class is prunasin beta-D-glucohydrolase. (wikipedia.org)
Also known as Periplasmic beta-glucosidase (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase). (mybiosource.com)

Cellulose is a polymer composed of beta-1,4-linked glucosyl residues. (wikipedia.org)
The most significant oligosaccharide beta-glucosidase reacts with is cellulose. (wikipedia.org)
During the digestive process of the bonnethead shark, the acidic stomach weakens the cell walls of the seagrass and allows for beta-glucosidase to enter the cell and digest the cellulose. (wikipedia.org)
A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was purified to homogeneity after cultivation on a cellulose and xylan rich medium. (lu.se)
The formation and location of endo-1,4-beta-glucanases and beta-glucosidases were studied in cultures of Cellulomonas uda grown on microcrystalline cellulose, carboxymethyl cellulose, printed newspaper, and some mono- or disaccharides. (helmholtz-hzi.de)
Some characteristics such as the optimal pH for and the thermostability of the endoglucanases and beta-glucosidases and the end products of cellulose degradation were determined. (helmholtz-hzi.de)

redefine GBA2 activity as the beta-glucosidase that is sensitive to inhibition by N-butyldeoxygalactonojirimycin. (antikoerper-online.de)

However, humans do require beta-glucosidase, Lysosomal β-glucosidase, as it plays an important role in the degradation of glycosphingolipids. (wikipedia.org)
GBA1 endodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glucosylceramide. (rndsystems.com)
Below are the list of possible Lysosomal beta glucosidase products. (mybiosource.com)
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. (genecards.org)

Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. (uniprot.org)
Detects human Cytosolic beta ‑Glucosidase/GBA3 in direct ELISAs and Western blots. (rndsystems.com)
Detection of Human Cytosolic beta ‑Glucosidase/GBA3 by Western Blot Western blot shows lysates of human kidney (cortex) tissue. (rndsystems.com)
PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human Cytosolic beta ‑Glucosidase/GBA3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5969) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). (rndsystems.com)
A specific band was detected for Cytosolic beta ‑Glucosidase/GBA3 at approximately XXX kDa (as indicated). (rndsystems.com)
GBA3 is a cytosolic beta-glucosidase and is predominantly expressed in liver. (rndsystems.com)
These data indicate that cytosolic beta-glucosidase is a hepatocyte-specific enzyme, and support the hypothesis that cytosolic beta-glucosidase in the liver functions to hydrolyze small glucosides absorbed by the intestine. (wikigenes.org)

The enzyme is purified by anion-exchange chromatography, the molecular mass and isoelectric point of purified beta-glucosidase are measured by sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and isoelectric focusing and the stability and kinetic parameters of the enzyme assessed by spectrophotometry. (semanticscholar.org)
We have isolated a heat-stable, low molecular weight activator peptide(s) from monkey parotid gland that specifically activated human salivary beta-D-glucosidase. (ias.ac.in)

Cys) of the retaining beta-glucosidase from Agrobacterium sp. (ubc.ca)

We analyzed the activities of CBE-sensitive β-glucosidase (GBA1) and AMP-DNM-sensitive β-glucosidase (GBA2) in total cell lysates and PM of human fibroblast cell lines from control (normal) subjects and from patients with GD clinical types 1, 2, and 3. (biomedsearch.com)

See the reference protein sequence for MULTISPECIES: beta-glucosidase (WP_074056525.1). (nih.gov)
Crystallographic studies of ReCel3A revealed a highly N-glycosylated three-domain dimeric protein, as has been observed previously for glycoside hydrolase family 3 beta-glucosidases. (diva-portal.org)

Analysis of the exocellular activity of Candida molischiana 35M5N grown on different carbon sources revealed that the biosynthesis of beta-glucosidase is derepressed in this yeast strain. (pasteur.fr)
in this work, the production of a beta-glucosidase by an Aureobasidium pullulans strain (Ap-beta-gl) isolated from grape ecosystems was evaluated. (unifesp.br)
The β- glucosidases activity of these three potential cellulolytic bacteria was performed by measuring the release of PNP using pNPG as a substrate and interestingly D4 strain was resulted with β-glucosidases negative where B1 strain was found to have efficient for β-glucosidases activity. (omicsonline.org)

However, recent studies of the shark's hindgut has found that it has a high activity level of beta glucosidase. (wikipedia.org)
Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. (uniprot.org)
One Unit of β-glucosidase activity is defined as the amount of enzyme required to release one µmole of of p -nitrophenol ( p NP) per minute from p -nitrophenyl-β-D-glucopyranoside (5 mM) in sodium acetate buffer (100 mM), pH 5.0 at 40 o C. (megazyme.com)
Highly fluorescent β-glucosidase probe for monitoring β-glucosidase activity where 1st order kinetics are desired. (antibody-antibodies.com)
The enzyme is active against a wide range of aryl beta-glycosides and beta-linked disaccharides, with beta-galactosidase activity only slightly less than beta-glucosidase activity, and significant beta-xylosidase activity. (waikato.ac.nz)
Subsequent kinetic analysis indeed showed that SPy1599 has 6-phospho-beta-glucosidase (EC 3.2.1.86) activity. (ubc.ca)
The extracellular beta-glucosidaseactivity was 84.78 mU/mL broth and the extracellular cellobiase activity of E. coli P81 (pUC19-bglB) was 32.32 mU/mL broth. (bvsalud.org)
Distinguished from most of the beta-glucosidases derived from fungi , which display the highest activities under acidic conditions, rBgl1B exhibited relatively higher activity and stability at pH between 7.0 and 9.0. (bvsalud.org)
beta-Glucosidase activity was isolated and had a Km of 0.25mM for the substrate p-nitrophenyl-beta-D-glucoside. (ulster.ac.uk)
In this study, cellulolytic bacteria with potential β-glucosidases activity were isolated and screened from biogas plant effluent and dairy effluent near Jahangirnagar University campus. (omicsonline.org)

Cellulases ( endoglucanases ), cellobiosidases ( exoglucanases ), and beta-glucosidases are required by organisms (some fungi , bacteria ) that can consume it. (wikipedia.org)

Microbial beta-glucosidases have been used for the enhancement of wine aroma. (unifesp.br)

This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. (nih.gov)

Beta-glucosidases, Cellulases (endoglucanases), cellobiosidases (exoglucanases) are required by a number of organisms to consume it. (wikipedia.org)

In this study, it is shown that substituting the beta-glucosidase from H. jecorina (HjCel3A) with the beta-glucosidase Cel3A from the thermophilic fungus Rasamsonia emersonii (ReCel3A) in enzyme mixtures results in increased efficiency in the saccharification of lignocellulosic materials. (diva-portal.org)
The production of beta-glucosidase by the ligninolytic fungus Pleurotus ostreatus has been studied in different culture media containing agro-industrial wastes. (semanticscholar.org)
In this study, a β-glucosidase coding gene (bgl) of the zygomycete fungus Rhizomucor miehei has been cloned and characterized. (usda.gov)

The objective of this study was thus to investigate production profiles of endoglucanase, β-glucosidase, xylanase, and reducing sugars grown on mineral minimum nutrient media containing different agricultural residues. (ajas.info)

The hydrolytic step was catalysed by a double residue (N221S, P342L) mutant of the thermostable beta-glucosidase (TnBgl1A), isolated from the thermophile Thermotoga neapolitana and cloned and produced in E. coli. (lu.se)

GBA3 efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiological beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. (rndsystems.com)

Liquid chromatographic and electrophoretic characterisation of extracellular beta-glucosidase of Pleurotus ostreatus grown in organic waste. (semanticscholar.org)
Endo-1,4-Glucanases were found to be extracellular, but a very small amount of cell-bound endo-1,4-beta-glucanase was considered to be the basal endoglucanase level of the cells. (helmholtz-hzi.de)

The B. mori beta-glucosidase mRNA expression in larval midgut was detectable only during feeding period, whereas its expression was downregulated during starvation. (unboundmedicine.com)

An isolated gene from Neosartorya fischeri NRRL181 encoding a β-glucosidase (BGL) was cloned, and its nucleotide sequence was determined. (dtu.dk)

A digestive beta-glucosidase cDNA was cloned from the silkworm, Bombyx mori. (unboundmedicine.com)

Purification and properties of a stable beta-glucosidase from an extremely thermophilic anaerobic bacterium. (waikato.ac.nz)

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Organisms6

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Chemicals and Drugs40

Phenomena and Processes3

Technology, Industry, Agriculture2

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Health Care1

The DNA binding site of the Dof protein NtBBF1 is essential for tissue-specific and auxin-regulated expression of the rolB oncogene in plants. (1/814)

Stochastic and nonstochastic post-transcriptional silencing of chitinase and beta-1,3-glucanase genes involves increased RNA turnover-possible role for ribosome-independent RNA degradation. (2/814)

Molecular cloning and expression of the novel fungal beta-glucosidase genes from Humicola grisea and Trichoderma reesei. (3/814)

Properties of beta-glucosidase in cultured skin fibroblasts from controls and patients with Gaucher disease. (4/814)

Growth of Azospirillum irakense KBC1 on the aryl beta-glucoside salicin requires either salA or salB. (5/814)

Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis. (6/814)

Cellobiose transport by mixed ruminal bacteria from a Cow. (7/814)

Transcriptional regulation in the hyperthermophilic archaeon Pyrococcus furiosus: coordinated expression of divergently oriented genes in response to beta-linked glucose polymers. (8/814)

beta-Glucosidase

Oligo-1,6-Glucosidase

alpha-Glucosidases

Glucosidases

1-Deoxynojirimycin

Indolizines

Glycogen Debranching Enzyme System

Oligosaccharides

Interleukin-1beta

Mannosidases

Imino Pyranoses

Rauwolfia

beta 2-Microglobulin

Glucosamine

Calnexin

Endoplasmic Reticulum

Swainsonine

Polysaccharides

Carbohydrate Metabolism, Inborn Errors

Glycoside Hydrolases

Isomaltose

Glycosylation

Carbohydrate Sequence

Receptors, Adrenergic, beta

Integrin beta3

Glycoproteins

Molecular Sequence Data

Acarbose

Hexosaminidases

Glycogen Storage Disease Type II

Trisaccharides

Nipah Virus

Escherichia coli

Cellobiose

Escherichia coli Proteins

Arbutin

Phenylacetates

Disaccharides

Glucosides

Dictionaries, Medical

Glucosylceramidase

Gaucher Disease

Saposins

Dictionaries as Topic

Lignin

Biofuels

Cellulases

Cellulose

Hydrolysis

Cellulase

Spirostans

Costus

Tribulus

Rhizome

Glycosides

Polygonatum

Cardiac Glycosides

The DNA binding site of the Dof protein NtBBF1 is essential for tissue-specific and auxin-regulated expression of the rolB oncogene in plants. (1/814)

Stochastic and nonstochastic post-transcriptional silencing of chitinase and beta-1,3-glucanase genes involves increased RNA turnover-possible role for ribosome-independent RNA degradation. (2/814)

Molecular cloning and expression of the novel fungal beta-glucosidase genes from Humicola grisea and Trichoderma reesei. (3/814)

Properties of beta-glucosidase in cultured skin fibroblasts from controls and patients with Gaucher disease. (4/814)

Growth of Azospirillum irakense KBC1 on the aryl beta-glucoside salicin requires either salA or salB. (5/814)

Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis. (6/814)

Cellobiose transport by mixed ruminal bacteria from a Cow. (7/814)

Transcriptional regulation in the hyperthermophilic archaeon Pyrococcus furiosus: coordinated expression of divergently oriented genes in response to beta-linked glucose polymers. (8/814)

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