A carotenoid that is a precursor of VITAMIN A. It is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC). (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Engewood, CO, 1995.)
The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons consisting of a polyisoprene backbone.
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
A genus of zygomycetous fungi in the family Mucoraceae, order MUCORALES, forming mycelia having a metallic sheen. It has been used for research on phototropism.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as EC 1.13.11.21 and EC 1.18.3.1.
An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.
A carotenoid produced in most carotenogenic organisms. It is one of several sequentially synthesized molecules that are precursors to BETA CAROTENE.
An enzyme that catalyzes the condensation of two molecules of geranylgeranyl diphosphate to give prephytoene diphosphate. The prephytoene diphosphate molecule is a precursor for CAROTENOIDS and other tetraterpenes.
A family of gram-negative, aerobic bacteria utilizing only one-carbon organic compounds and isolated from in soil and water.
Inhaling and exhaling the smoke of burning TOBACCO.
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
A species of METHYLOCOCCUS which forms capsules and is capable of autotrophic carbon dioxide fixation. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Oxygenated forms of carotenoids. They are usually derived from alpha and beta carotene.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.
A xanthophyll found in the major LIGHT-HARVESTING PROTEIN COMPLEXES of plants. Dietary lutein accumulates in the MACULA LUTEA.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Enzymes of the isomerase class that catalyze reactions in which a group can be regarded as eliminated from one part of a molecule, leaving a double bond, while remaining covalently attached to the molecule. (From Enzyme Nomenclature, 1992) EC 5.5.
A species of METHYLOSINUS which is capable of degrading trichloroethylene and other organic pollutants.
A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site.
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
A genus of gram-negative, ellipsoidal or rod-shaped bacteria whose major source of energy and reducing power is from the oxidation of ammonia to nitrite. Its species occur in soils, oceans, lakes, rivers, and sewage disposal systems.
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
Tumors or cancer of the LUNG.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
A plant species of the family APIACEAE that is widely cultivated for the edible yellow-orange root. The plant has finely divided leaves and flat clusters of small white flowers.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as octane and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.
A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179)
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
A benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. It is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. It is also used topically in treatment of RHEUMATIC DISEASES and INFLAMMATION of the mouth and throat.
Thirteen-carbon butene cyclohexene degradation products formed by the cleavage of CAROTENOIDS. They contribute to the flavor of some FRUIT. Ionone should not be confused with the similarly named ionol.
An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water. EC 1.14.16.2.
An organism of the vegetable kingdom suitable by nature for use as a food, especially by human beings. Not all parts of any given plant are edible but all parts of edible plants have been known to figure as raw or cooked food: leaves, roots, tubers, stems, seeds, buds, fruits, and flowers. The most commonly edible parts of plants are FRUIT, usually sweet, fleshy, and succulent. Most edible plants are commonly cultivated for their nutritional value and are referred to as VEGETABLES.
The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed)
One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
Placing of a hydroxyl group on a compound in a position where one did not exist before. (Stedman, 26th ed)
Systems of enzymes which function sequentially by catalyzing consecutive reactions linked by common metabolic intermediates. They may involve simply a transfer of water molecules or hydrogen atoms and may be associated with large supramolecular structures such as MITOCHONDRIA or RIBOSOMES.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
An enzyme that utilizes NADH or NADPH to reduce FLAVINS. It is involved in a number of biological processes that require reduced flavin for their functions such as bacterial bioluminescence. Formerly listed as EC 1.6.8.1 and EC 1.5.1.29.
A flavoprotein that catalyzes the reduction of heme-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. EC 1.6.2.4.
Regular course of eating and drinking adopted by a person or animal.
These enzymes catalyze the elimination of ammonia from amidines with the formation of a double bond. EC 4.3.2.
Derivatives of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton. Flavin derivatives serve an electron transfer function as ENZYME COFACTORS in FLAVOPROTEINS.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
The rate dynamics in chemical or physical systems.
An order of zygomycetous fungi, usually saprophytic, causing damage to food in storage, but which may cause respiratory infection or MUCORMYCOSIS in persons suffering from other debilitating diseases.
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
A bacterial genus of the order ACTINOMYCETALES.
A class of compounds composed of repeating 5-carbon units of HEMITERPENES.
An antiseptic and disinfectant aromatic alcohol.
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms are associated with plants as pathogens, saprophytes, or as constituents of the epiphytic flora.
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
A widely used industrial solvent.

Etiology:
The exact cause of OSF is not known, but it is believed to be related to repeated trauma to the mucous membranes in the mouth, such as from sharp teeth or rough fillings, and chronic exposure to certain chemicals or allergens. It is more common in people who smoke or chew tobacco, and those who have a family history of the condition.

Symptoms:
The symptoms of OSF can vary in severity, but may include:

* Redness and irritation of the mucous membranes in the mouth and throat
* Difficulty swallowing or speaking due to stiffness of the membranes
* Pain or discomfort when eating or drinking hot or spicy foods
* Open sores or ulcers on the tongue, lips, or inside the cheeks
* White patches or plaques on the mucous membranes
* Difficulty moving the jaw or tongue due to scarring and stiffness

Diagnosis:
OSF is typically diagnosed based on a physical examination of the mouth and throat, as well as a review of the patient's medical history. A biopsy may be performed to confirm the diagnosis and rule out other conditions.

Treatment:
There is no cure for OSF, but treatment can help manage the symptoms and slow the progression of the condition. Treatment options may include:

* Medications to reduce inflammation and pain, such as corticosteroids or nonsteroidal anti-inflammatory drugs (NSAIDs)
* Mouthwashes or topical treatments to reduce irritation and promote healing
* Dental treatments, such as filling or crowning teeth that are causing trauma to the mucous membranes
* Dietary modifications to avoid hot or spicy foods and drinks
* Speech therapy to improve jaw mobility and swallowing function.

Prognosis:
The prognosis for OSF is generally poor, as the condition can be severe and difficult to manage. In some cases, OSF may lead to serious complications such as infection, sepsis, or respiratory failure. However, with prompt and appropriate treatment, patients with OSF may experience some improvement in their symptoms and quality of life.

Prevention:
There is no known prevention for OSF, but good oral hygiene practices and avoiding hot or spicy foods and drinks may help reduce the risk of developing the condition.

Other Names:
Orthokeratotic oral lichen planus, chronic benign migratory glossitis, oral lichenoid contact dermatitis, oral mucosal lesions, stomatitis, ulcerative, and vesiculobullous.

There are different types of cataracts, including:

1. Nuclear cataract: This is the most common type of cataract and affects the center of the lens.
2. Cortical cataract: This type of cataract affects the outer layer of the lens and can cause a "halo" effect around lights.
3. Posterior subcapsular cataract: This type of cataract affects the back of the lens and is more common in younger people and those with diabetes.
4. Congenital cataract: This type of cataract is present at birth and can be caused by genetic factors or other conditions.

Symptoms of cataracts can include:

* Blurred vision
* Double vision
* Sensitivity to light
* Glare
* Difficulty seeing at night
* Fading or yellowing of colors

Cataracts can be diagnosed with a comprehensive eye exam, which includes a visual acuity test, dilated eye exam, and imaging tests such as ultrasound or optical coherence tomography (OCT).

Treatment for cataracts typically involves surgery to remove the clouded lens and replace it with an artificial one called an intraocular lens (IOL). The type of IOL used will depend on the patient's age, visual needs, and other factors. In some cases, cataracts may be removed using a laser-assisted procedure.

In addition to surgery, there are also non-surgical treatments for cataracts, such as glasses or contact lenses, which can help improve vision. However, these treatments do not cure the underlying condition and are only temporary solutions.

It's important to note that cataracts are a common age-related condition and can affect anyone over the age of 40. Therefore, it's important to have regular eye exams to monitor for any changes in vision and to detect cataracts early on.

In summary, cataracts are a clouding of the lens in the eye that can cause blurred vision, double vision, sensitivity to light, and other symptoms. Treatment typically involves surgery to remove the clouded lens and replace it with an artificial one, but non-surgical treatments such as glasses or contact lenses may also be used. Regular eye exams are important for detecting cataracts early on and monitoring vision health.

1. Coronary artery disease: The narrowing or blockage of the coronary arteries, which supply blood to the heart.
2. Heart failure: A condition in which the heart is unable to pump enough blood to meet the body's needs.
3. Arrhythmias: Abnormal heart rhythms that can be too fast, too slow, or irregular.
4. Heart valve disease: Problems with the heart valves that control blood flow through the heart.
5. Heart muscle disease (cardiomyopathy): Disease of the heart muscle that can lead to heart failure.
6. Congenital heart disease: Defects in the heart's structure and function that are present at birth.
7. Peripheral artery disease: The narrowing or blockage of blood vessels that supply oxygen and nutrients to the arms, legs, and other organs.
8. Deep vein thrombosis (DVT): A blood clot that forms in a deep vein, usually in the leg.
9. Pulmonary embolism: A blockage in one of the arteries in the lungs, which can be caused by a blood clot or other debris.
10. Stroke: A condition in which there is a lack of oxygen to the brain due to a blockage or rupture of blood vessels.

There are several types of lung neoplasms, including:

1. Adenocarcinoma: This is the most common type of lung cancer, accounting for approximately 40% of all lung cancers. It is a malignant tumor that originates in the glands of the respiratory tract and can be found in any part of the lung.
2. Squamous cell carcinoma: This type of lung cancer accounts for approximately 25% of all lung cancers and is more common in men than women. It is a malignant tumor that originates in the squamous cells lining the airways of the lungs.
3. Small cell lung cancer (SCLC): This is a highly aggressive form of lung cancer that accounts for approximately 15% of all lung cancers. It is often found in the central parts of the lungs and can spread quickly to other parts of the body.
4. Large cell carcinoma: This is a rare type of lung cancer that accounts for only about 5% of all lung cancers. It is a malignant tumor that originates in the large cells of the respiratory tract and can be found in any part of the lung.
5. Bronchioalveolar carcinoma (BAC): This is a rare type of lung cancer that originates in the cells lining the airways and alveoli of the lungs. It is more common in women than men and tends to affect older individuals.
6. Lymphangioleiomyomatosis (LAM): This is a rare, progressive, and often fatal lung disease that primarily affects women of childbearing age. It is characterized by the growth of smooth muscle-like cells in the lungs and can lead to cysts, lung collapse, and respiratory failure.
7. Hamartoma: This is a benign tumor that originates in the tissue of the lungs and is usually found in children. It is characterized by an overgrowth of normal lung tissue and can be treated with surgery.
8. Secondary lung cancer: This type of cancer occurs when cancer cells from another part of the body spread to the lungs through the bloodstream or lymphatic system. It is more common in people who have a history of smoking or exposure to other carcinogens.
9. Metastatic cancer: This type of cancer occurs when cancer cells from another part of the body spread to the lungs through the bloodstream or lymphatic system. It is more common in people who have a history of smoking or exposure to other carcinogens.
10. Mesothelioma: This is a rare and aggressive form of cancer that originates in the lining of the lungs or abdomen. It is caused by asbestos exposure and can be treated with surgery, chemotherapy, and radiation therapy.

Lung diseases can also be classified based on their cause, such as:

1. Infectious diseases: These are caused by bacteria, viruses, or other microorganisms and can include pneumonia, tuberculosis, and bronchitis.
2. Autoimmune diseases: These are caused by an overactive immune system and can include conditions such as sarcoidosis and idiopathic pulmonary fibrosis.
3. Genetic diseases: These are caused by inherited mutations in genes that affect the lungs and can include cystic fibrosis and primary ciliary dyskinesia.
4. Environmental diseases: These are caused by exposure to harmful substances such as tobacco smoke, air pollution, and asbestos.
5. Radiological diseases: These are caused by exposure to ionizing radiation and can include conditions such as radiographic breast cancer and lung cancer.
6. Vascular diseases: These are caused by problems with the blood vessels in the lungs and can include conditions such as pulmonary embolism and pulmonary hypertension.
7. Tumors: These can be benign or malignant and can include conditions such as lung metastases and lung cancer.
8. Trauma: This can include injuries to the chest or lungs caused by accidents or other forms of trauma.
9. Congenital diseases: These are present at birth and can include conditions such as bronchopulmonary foregut malformations and congenital cystic adenomatoid malformation.

Each type of lung disease has its own set of symptoms, diagnosis, and treatment options. It is important to seek medical attention if you experience any persistent or severe respiratory symptoms, as early diagnosis and treatment can improve outcomes and quality of life.

Causes of Vitamin A Deficiency:

1. Poor diet: A diet that is deficient in vitamin A-rich foods, such as dark leafy greens, liver, and dairy products, can lead to a deficiency.
2. Malabsorption: Certain medical conditions, such as celiac disease, Crohn's disease, and pancreatic insufficiency, can impair the body's ability to absorb vitamin A from food.
3. Pregnancy and lactation: The increased demand for nutrients during pregnancy and lactation can lead to a deficiency if the diet does not provide enough vitamin A.
4. Chronic diseases: Certain chronic diseases, such as HIV/AIDS, tuberculosis, and kidney disease, can increase the risk of vitamin A deficiency.

Symptoms of Vitamin A Deficiency:

1. Night blindness: Difficulty seeing in low light environments, such as at night or in dimly lit rooms.
2. Blindness: In severe cases, vitamin A deficiency can lead to complete blindness.
3. Dry skin: Vitamin A is important for healthy skin, and a deficiency can cause dry, rough skin that may be prone to dermatitis.
4. Increased risk of infections: Vitamin A plays a role in immune function, and a deficiency can increase the risk of respiratory, gastrointestinal, and other infections.
5. Bitot's spot: A condition that causes white patches on the cornea, which can be a sign of vitamin A deficiency.
6. Dry eyes: Vitamin A is important for healthy tear production, and a deficiency can cause dry, itchy eyes.
7. Weakened immune system: Vitamin A plays a role in immune function, and a deficiency can weaken the body's ability to fight off infections.
8. Increased risk of cancer: Some studies suggest that a vitamin A deficiency may increase the risk of certain types of cancer, such as colon, breast, and lung cancer.
9. Reproductive problems: Vitamin A is important for reproductive health, and a deficiency can cause irregular menstrual cycles, infertility, and other reproductive problems.
10. Poor wound healing: Vitamin A is important for healthy skin and wound healing, and a deficiency can cause poor wound healing and an increased risk of infection.

In conclusion, vitamin A deficiency is a common problem worldwide, especially in developing countries, and can have serious consequences if left untreated. It is important to ensure adequate intake of vitamin A through diet or supplements, particularly for pregnant women, children, and individuals with chronic illnesses. If you suspect you may have a vitamin A deficiency, it is important to speak with your healthcare provider to determine the appropriate course of treatment.

... monooxygenase (BCO1; EC 1.14.99.36) from animals, which cleaves beta-carotene symmetrically at the central double bond to yield ... Beta-carotene-9',10'-dioxygenase (BCO2) from animals, which cleaves beta-carotene asymmetrically to apo-10'-beta-carotenal and ... which converts beta-apocarotenals rather than beta-carotene into retinal. This protein has a seven-bladed beta-propeller ... Carotenoids such as beta-carotene, lycopene, lutein and beta-cryptoxanthin are produced in plants and certain bacteria, algae ...
... is synthesized from beta-carotene. The beta-carotene is firstly cleaved into beta-carotene 15-15'-monooxygenase ... monooxygenase". Pure and Applied Chemistry. 74 (8): 1397-1408. doi:10.1351/pac200274081397. Vivant Pharmaceuticals, LLC Press ... Woggon, Wolf-D. (1 January 2002). "Oxidative cleavage of carotenoids catalyzed by enzyme models and beta-carotene 15,15´- ... Tretinoin is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17) ...
Gong X, Tsai SW, Yan B, Rubin LP (2006). "Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'- ... monooxygenase gene expression". BMC Molecular Biology. 7: 7. doi:10.1186/1471-2199-7-7. PMC 1526748. PMID 16504037. MEF2B+ ... 187 (1): 15-23. doi:10.1620/tjem.187.15. PMID 10458488. Youn HD, Sun L, Prywes R, Liu JO (Oct 1999). "Apoptosis of T cells ...
... monooxygenase that converts beta-carotene into retinal". Biotechnology Letters. 31 (3): 403-8. doi:10.1007/s10529-008-9873-4. ... Kim YS, Park CS, Oh DK (July 2010). "Retinal production from beta-carotene by beta-carotene 15,15'-dioxygenase from an ... beta-4'-apo-β-carotenal, alpha-carotene and gamma-carotene in decreasing order, creating one retinal molecule, all of these ... In enzymology, beta-carotene 15,15'-dioxygenase, (EC 1.13.11.63) is an enzyme with systematic name beta-carotene:oxygen 15,15'- ...
Among the carotenes, β-carotene is distinguished by having beta-rings at both ends of the molecule. β-Carotene is ... monooxygenase. Isolation of β-carotene from fruits abundant in carotenoids is commonly done using column chromatography. It can ... Beta-carotene, MedlinePlus WebMD. "Find a Vitamin or Supplement - Beta Carotene". Retrieved 29 May 2012. Stargrove, Mitchell ( ... "Beta-Carotene Interactions". Retrieved 28 May 2012. Meschino Health. "Comprehensive Guide to Beta-Carotene". Retrieved 29 May ...
RPE65 isomerohydrolases are homologous with beta-carotene monooxygenases; the homologous ninaB enzyme in Drosophila has both ... For example: beta-carotene + O2 → 2 retinal, catalyzed by a beta-carotene 15,15'-monooxygenase or a beta-carotene 15,15'- ... either from α-carotene or β-carotene - both of which are carotenes. They also produce it from β-cryptoxanthin, a type of ... Woggon, Wolf-D. (2002). "Oxidative cleavage of carotenoids catalyzed by enzyme models and beta-carotene 15,15'-monooxygenase". ...
... the carotenoids alpha-carotene, β-carotene, gamma-carotene, and the xanthophyll beta-cryptoxanthin (all of which contain β- ... monooxygenase, coded for by the BCMO1 gene, responsible for symmetrically cleaving β-carotene into retinal. Absorbed β-carotene ... to 2 μg β-carotene dissolved in oil, to 6 μg β-carotene in foods, and to 12 μg of either α-carotene, γ-carotene, or β- ... It is associated with a high blood β-carotene value. This can occur after a month or two of consumption of beta-carotene rich ...
... beta-carotene 15,15'-monooxygenase MeSH D08.811.682.690.708.392.468 - Linoleoyl-CoA desaturase MeSH D08.811.682.690.708.392.625 ... camphor 5-monooxygenase MeSH D08.811.682.690.708.170.500 - alkane 1-monooxygenase MeSH D08.811.682.690.708.170.915 - steroid ... 4-beta-glucosidase MeSH D08.811.277.450.420.200.600 - glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 - glucan ... 4-beta-cellobiosidase MeSH D08.811.277.450.420.200.450 - endo-1,3(4)-beta-glucanase MeSH D08.811.277.450.420.200.500 - glucan 1 ...
... carotenol to beta-apo-14'-carotenal by an enzyme different from beta-carotene-15,15'-dioxygenase". Biochemistry. Biokhimiia. 62 ... internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is 8'-apo-beta-carotenol: ... Apo-beta-carotenoid-14',13'-dioxygenase (EC 1.13.12.12) is an enzyme that catalyzes the chemical reaction 8'-apo-beta-carotenol ... apo-beta-carotenol and oxygen, whereas its two products are 14'-apo-beta-carotenal and water. This enzyme belongs to the family ...
... α-carotene) and beta-carotene (β-carotene). Gamma-, delta-, epsilon-, and zeta-carotene (γ, δ, ε, and ζ-carotene) also exist. ... monooxygenase to retinal, a form of vitamin A. β-Carotene can be stored in the liver and body fat and converted to retinal as ... ψ-carotene; δ-carotene (with one ε ring and one uncyclized end) is ε,ψ-carotene; ε-carotene is ε,ε-carotene lycopene is ψ,ψ- ... α-carotene is β,ε-carotene; β-carotene is β,β-carotene; γ-carotene (with one β ring and one uncyclized end that is labelled psi ...
The FDA recommends that pregnant women get their vitamin A from foods containing beta carotene and that they ensure that they ... monooxygenase cleaves β-carotene at the central double bond, creating an epoxide. This epoxide is then attacked by water ... March 1998). "Vitamin A and beta-carotene can improve nonheme iron absorption from rice, wheat and corn by humans". The Journal ... Challem J (1995). "Caution Urged With Vitamin A in Pregnancy: But Beta-Carotene is Safe". The Nutrition Reporter Newsletter. ...
Vitamin A is an essential nutrient for mammals which takes form in either retinol or the provitamin beta-Carotene. It helps ... Notably, dopamine β-mono-oxygenase is affected by copper deficiency leading to increased dopamine and decreased norepinephrine ... The foods highest in vitamin A are any pigmented fruits and vegetables and leafy green vegetables also provide beta-Carotene.[ ... The ketone body beta-hydroxybutyrate is a fuel source for the brain during times of fasting when blood glucose levels fall. ...
4-olide isomerase Beta-carotene isomerase Farnesol 2-isomerase Furylfuramide isomerase Linoleate isomerase Maleate isomerase ... Renilla-luciferin 2-monooxygenase EC 1.13.12.5 Cypridina-luciferin 2-monooxygenase EC 1.13.12.6 Firefly luciferase EC 1.13.12.7 ... Watasenia-luciferin 2-monooxygenase EC 1.13.12.8 Oplophorus-luciferin 2-monooxygenase EC 1.13.12.13 Cytochrome P450 oxidase ... Beta-lactamase (EC 3.5.2.6) Category:EC 3.5.3 (In linear amidines) Arginase (EC 3.5.3.1) Category:EC 3.5.4 (In cyclic amidines ...
Li FJ, Shen L, Ji HF (2012). "Dietary intakes of vitamin E, vitamin C, and β-carotene and risk of Alzheimer's disease: a meta- ... Peptidylglycine alpha-amidating monooxygenase amidates peptide hormones by removing the glyoxylate residue from their c- ... Kaufman S (1974). "Dopamine-beta-hydroxylase". Journal of Psychiatric Research. 11: 303-316. doi:10.1016/0022-3956(74)90112-5. ... Eipper BA, Milgram SL, Husten EJ, Yun HY, Mains RE (1993). "Peptidylglycine alpha-amidating monooxygenase: a multifunctional ...
... monooxygenase Synonymes. Carotene dioxygenase beta, beta-Carotene-15,15-dioxygenase beta, beta-Carotene-15,15-monooxygenase ... Carotene dioxygenase. beta, beta-Carotene-15,15-dioxygenase. beta, beta-Carotene-15,15-monooxygenase. beta-Carotene 15,15- ... A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as ... monooxygenase - Concept préféré Concept UI. M0072771. Terme préféré. beta-Carotene 15,15- ...
Specifically, once absorbed, carotenoids are cleaved by carotenoid cleavage oxygenases (CCOs), such as Beta-carotene 15,15- ... monooxygenase (BCO1), to produce all-trans retinal that subsequently gets converted into all-trans retinol. CRBP2 bound retinol ... Specifically, once absorbed, carotenoids are cleaved by carotenoid cleavage oxygenases (CCOs), such as Beta-carotene 15,15{\ ... Specifically, once absorbed, carotenoids are cleaved by carotenoid cleavage oxygenases (CCOs), such as Beta-carotene 15,15- ...
... ß-carotene ([rs6564851 beta-carotene 15,15-monooxygenase 1 (BCMO1)]. Meta-analysis was used to pool within-study effects of ... We also observed a triglyceride-independent association between the minor allele and lower BMI (pooled beta on z-score=â -0.04 ... pooled beta for APOE ε4 effect on semantic fluency z score = -0.02; 95 % CI = -0.05 to 0.02; p value = 0.3; n = 18,796). ... We identified 15 common (minor allele frequency, MAF ≥5%) and nine low-frequency or rare (MAF ...
Human bCMO1(Beta-Carotene-15,15′-Monooxygenase 1) ELISA Kit. *Human BFAR(Bifunctional Apoptosis Regulator) ELISA Kit ... Human HSD17b1(17-Beta-Hydroxysteroid Dehydrogenase Type 1) ELISA Kit. *Human HSPA1L(Heat Shock 70kDa Protein 1 Like Protein) ... Human b3GNT3(Beta-1,3-N-Acetylglucosaminyltransferase 3) ELISA Kit. *Human BAI1(Brain Specific Angiogenesis Inhibitor 1) ELISA ... Human ETFb(Electron Transfer Flavoprotein Beta Polypeptide) ELISA Kit. *Human ETS1(V-Ets Erythroblastosis Virus E26 Oncogene ...
Human bCMO1(Beta-Carotene-15,15′-Monooxygenase 1) ELISA Kit. *Human BFAR(Bifunctional Apoptosis Regulator) ELISA Kit ... Human HSD17b1(17-Beta-Hydroxysteroid Dehydrogenase Type 1) ELISA Kit. *Human HSPA1L(Heat Shock 70kDa Protein 1 Like Protein) ... Human b3GNT3(Beta-1,3-N-Acetylglucosaminyltransferase 3) ELISA Kit. *Human BAI1(Brain Specific Angiogenesis Inhibitor 1) ELISA ... Human ETFb(Electron Transfer Flavoprotein Beta Polypeptide) ELISA Kit. *Human ETS1(V-Ets Erythroblastosis Virus E26 Oncogene ...
Common variation in the beta-carotene 15,15-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide ...
beta-carotene 3-hydroxylase. 1.14.15.25. p-cymene methyl-monooxygenase. 1.14.15.26. toluene methyl-monooxygenase. ... cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate. ... cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate. ...
Carotenoids are provitamins of vitamin A. Carotenoids widely distributed in plants, particularly a-, b-, and g-carotene. The ... A more recent study by the same investigators found that treatment with either a medication called a beta-blocker or high-dose ... kynurenine mono-oxygenase. Severe riboflavin deficiency can decrease the conversion of tryptophan to NAD and NADP, increasing ... b-Carotene, a symmetrical molecule, is cleaved in its center to yield two molecules of retinol. Retinol occurs in the tissues ...
... and identify the Wnt signaling pathway effector beta-catenin as a UBQLN4 substrate. Inhibition of beta-catenin function rescues ... β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35 Lutein/Zeaxanthin for the treatment of age- ... N-hydroxylating Rifampicin Monooxygenase Mechanism of Rifampicin inactivation in Nocardia farcinica Extensive migration of ... therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo A human pancreatic beta ...
CD131 Antigens use Cytokine Receptor Common beta Subunit. CD132 Antigens use Interleukin Receptor Common gamma Subunit ... Calcidiol 1-Monooxygenase use 25-Hydroxyvitamin D3 1-alpha-Hydroxylase. Calcifediol. Calciferols use Ergocalciferols ...
... monooxygenase 1 (BCMO1) gene, was associated with higher beta-carotene (p = 1.6 x 10(-24)) and alpha-carotene (p = 0.0001) ... Molecular and dietary regulation of beta,beta-carotene 15,15-monooxygenase 1 (BCMO1). Lietz G, Lange J, Rimbach G. Lietz G, et ... Effects were replicated in the Womens Health and Aging Study (n = 615) and in the alpha-Tocopherol, beta-Carotene Cancer ... Strong and weak plasma response to dietary carotenoids identified by cluster analysis and linked to beta-carotene 15,15- ...
Investigate biochemistry and molecular biology of related beta-carotene monooxygenases. Research additional functions of - ... Her major scientific focus is beta-carotene oxygenases 1 and 2 and their role in carotenoid metabolism and vitamin A ... "Key Role of histidines in mouse beta-carotene 15,15-monooxygenase activity." Eugenia Poliakov, Susan Gentleman, Francis X. ... "Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15- ...
... beta-Carotene 15,15-Monooxygenase ... but not β-carotene, in mid-childhood is associated with higher ... We investigated whether a higher intake of preformed vitamin A or pro-vitamin β-carotene in mid-childhood is associated with ... In contrast, there was no evidence for association with β-carotene. We also found some evidence for modification of the ... METHODS: In the Avon Longitudinal Study of Parents and Children, dietary intakes of preformed vitamin A and β-carotene ...
Beta-carotene 15, 15 Monooxygenase is a Peroxisome Proliferator Activated Receptor Target Gene ...
Monooxygenase, beta-Carotene Carotene Dioxygenase Cleaving Enzyme, beta-Carotene Dioxygenase, Carotene beta Carotene 15,15 ... Monooxygenase, beta-Carotene. Carotene Dioxygenase. Cleaving Enzyme, beta-Carotene. Dioxygenase, Carotene. beta Carotene 15,15 ... Monooxygenase beta Carotene Cleaving Enzyme beta, beta-Carotene-15,15-Dioxygenase beta, beta-Carotene-15,15-Monooxygenase ... Monooxygenase. beta Carotene Cleaving Enzyme. beta, beta-Carotene-15,15-Dioxygenase. beta, beta-Carotene-15,15-Monooxygenase ...
A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as ... beta-Carotene Cleaving Enzyme Registry Number. EC 1.14.99.36. Public MeSH Note. 2006; BETA-CAROTENE 15,15-MONOOXYGENASE was ... Carotene Dioxygenase beta, beta-Carotene-15,15-Dioxygenase beta, beta-Carotene-15,15-Monooxygenase beta-Carotene 15,15- ... Carotene Dioxygenase Term UI T102773. LexicalTag NON. ThesaurusID NLM (2006). beta-Carotene 15,15-Dioxygenase Term UI T102774 ...
A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as ... beta-Carotene Cleaving Enzyme Registry Number. EC 1.14.99.36. Public MeSH Note. 2006; BETA-CAROTENE 15,15-MONOOXYGENASE was ... Carotene Dioxygenase beta, beta-Carotene-15,15-Dioxygenase beta, beta-Carotene-15,15-Monooxygenase beta-Carotene 15,15- ... Carotene Dioxygenase Term UI T102773. LexicalTag NON. ThesaurusID NLM (2006). beta-Carotene 15,15-Dioxygenase Term UI T102774 ...
... beta 2-Glycoprotein I N0000169400 beta 2-Microglobulin N0000007226 beta Carotene N0000169947 beta Catenin N0000169677 beta ... Monooxygenase N0000169031 beta-Crystallin A Chain N0000169030 beta-Crystallin B Chain N0000169029 beta-Crystallins N0000168523 ... beta-Hexosaminidase beta Chain N0000175112 beta-Keratins N0000167683 beta-Lactamases N0000011162 beta-Lactams N0000170341 beta- ... beta-Alanine-Pyruvate Transaminase N0000166462 beta-Aminoethyl Isothiourea N0000167702 beta-Amylase N0000167866 beta-Carotene ...
Monooxygenase UI - D050559 MN - D8.811.682.690.708.392.312 MS - A monooxygenase that catalyzes the conversion of BETA-CAROTENE ... non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates TRANSCRIPTION of a variety of ... beta Cells, Pancreatic BX - Pancreatic beta Cells MH - Interferon Regulatory Factor-1 UI - D050856 MN - D12.644.360.24.303.124 ... Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also ...
Beta,beta-carotene 15,15-dioxygenase. 1 Select filter option. Cholesterol 24-hydroxylase. 1 Select filter option. Cholesterol ... monooxygenase activity. 25 Select filter option. aromatase activity. 12 Select filter option. metal ion binding. 9 Select ... alkane 1-monooxygenase activity. 4 Select filter option. enzyme binding. 4 Select filter option. estrogen 16-alpha-hydroxylase ... N,N-dimethylaniline monooxygenase activity. 6 Select filter option. NADP binding. 6 Select filter option. oxidoreductase ...
Beta,beta-carotene 15,15-dioxygenase. 1 Select filter option. Cholesterol 24-hydroxylase. 1 Select filter option. Cholesterol ... monooxygenase activity. 25 Select filter option. aromatase activity. 12 Select filter option. metal ion binding. 9 Select ... alkane 1-monooxygenase activity. 4 Select filter option. enzyme binding. 4 Select filter option. estrogen 16-alpha-hydroxylase ... N,N-dimethylaniline monooxygenase activity. 6 Select filter option. NADP binding. 6 Select filter option. oxidoreductase ...
... beta 2-Glycoprotein I beta 2-Microglobulin beta Carotene beta Catenin beta Karyopherins Beta Particles Beta Rhythm Beta ... Monooxygenase Beta-Cryptoxanthin beta-Crystallin A Chain beta-Crystallin B Chain beta-Crystallins beta-Cyclodextrins beta- ... beta-Lactamases beta-Lactams beta-Lipotropin beta-Mannosidase beta-Mannosidosis beta-MSH beta-N-Acetyl-Galactosaminidase beta-N ... beta-Globins Beta-Globulins beta-Glucans beta-Glucosidase beta-Hexosaminidase alpha Chain beta-Hexosaminidase beta Chain beta- ...
4. The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine ... Competitive regulation of human intestinal β-carotene 15,15-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear ... 9. Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf ... 1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta ...
16 mg of beta-carotene, or placebo were administered daily for 4 months. Sixteen clinical and cytological variables were ... The role of cytochrome P450 monooxygenase (MO)-mediated metabolism in DDM hepatotoxicity was evaluated using the MO inhibitors ... beta-naphthoflavone pretreatment had a more modest effect on DDM-induced hepatic insult. These results demonstrate that DDM ... aminobenzotriazole and SKF-525A and the MO inducers phenobarbital and beta-naphthoflavone. Aminobenzotriazole provided ...
... vitamin E and beta-carotene. These nutrients are the first effective treatment to slow the progression of AMD, a leading cause ... He continued over the next fifteen years to do surveys on mental health and other problems. ... cytochrome-P450 monooxygenases, which exerted a profound influence in many areas of research, including studies of the ... Amyloid-beta levels in both mice and people naturally fluctuate, they discovered, rising while awake and falling during sleep. ...
... , beta Caroteno , Tabaco/genética , Dioxigenases/genética , Proteínas de Plantas/genética , Carotenoides , Mutação ... Carotenoid analysis of the leaves from mutants showed that lutein and ß-carotene increased in line with the degree of color ... Indoleamine-2,3-dioxygenase, Trp-2,3-dioxygenase, kynurenine-3-monooxygenase, and Trp hydroxylase are the rate-limiting enzymes ... ß-carotene. To understand the possible role of tobacco CCD4 genes (NtCCD4-S, NtCCD4-T1 and NtCCD4-T2) in these processes, we ...
... tpx tr7 v47 tpu tpt v45 tr4 tpr theophyllin tr3 tpp tr2 tr1 v41 tpo epha8 tpn epha7 epha6 tpm epha5 tpl epha4 monooxygenases ... isobutylamide nuc1 dimethylcrocetin carbogen stellulata cluttering nub1 statements gln27glu silverman cibarius doorways fifteen ... danofloxacin pyrimidinethiol duclos equilibra misdirect martynoside raciborskii ecsit argentata cyp6d1 betacarotene indolamine ... overtiredness retama tfcp2 mannopine ureidosuccinate sideroblasts glycerylphosphorylcholine quiescence carotene pinnicaudatus ...
... monooxygenase (substance) {130046004 , SNOMED-CT } 6-beta-hydroxyhyoscyamine epoxidase (substance) {130024007 , SNOMED-CT } 6- ... Carotene 7,8-desaturase (substance) {130080001 , SNOMED-CT } Carveol dehydrogenase (substance) {129961003 , SNOMED-CT } ... Lignostilbene alpha beta-dioxygenase (substance) {130015003 , SNOMED-CT } Linalool 8-monooxygenase (substance) {130078007 , ... Peptide-aspartate beta-dioxygenase (substance) {130026009 , SNOMED-CT } Peptidylglycine monooxygenase (substance) {130175008 , ...
... beta-carotene 15,15-prime oxygenase 1,gngm c17orf85 gene,c17orf85 gene,C1824477,c17orf85,gngm t2r19,t2r19,C1426014,t2r48,gngm ... phenylalanine 4-monooxygenase,gngm cyp2d6*10 allele,cyp2d6 \* 10 allele,C1706118,cyp2d6j,gngm left pelvic girdle,leave pelvic ... beta 4,C1416784,lamb4,gngm laminin, beta 3,laminin , beta 3,C1416783,laminin b3,gngm laminin, beta 2,laminin , beta 2,C1416781, ... gngm beta-4,beta-4,C1540126,tubb3,gngm beta-3,beta-3,C1414290,eukaryotic translation elongation factor 1 beta 2 pseudogene 2, ...
... beta-carotene 15,15-prime oxygenase 1,gngm c17orf85 gene,c17orf85 gene,C1824477,c17orf85,gngm t2r19,t2r19,C1426014,t2r48,gngm ... phenylalanine 4-monooxygenase,gngm cyp2d6*10 allele,cyp2d6 \* 10 allele,C1706118,cyp2d6j,gngm left pelvic girdle,leave pelvic ... beta 4,C1416784,lamb4,gngm laminin, beta 3,laminin , beta 3,C1416783,laminin b3,gngm laminin, beta 2,laminin , beta 2,C1416781, ... gngm beta-4,beta-4,C1540126,tubb3,gngm beta-3,beta-3,C1414290,eukaryotic translation elongation factor 1 beta 2 pseudogene 2, ...
  • Monooxigenasa que cataliza la conversión del BETA-CAROTENO en dos moléculas de RETINAL. (bvsalud.org)
  • A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL . (bvsalud.org)
  • Specifically, once absorbed, carotenoids are cleaved by carotenoid cleavage oxygenases (CCOs), such as Beta-carotene 15,15'-monooxygenase (BCO1), to produce all-trans retinal that subsequently gets converted into all-trans retinol. (umn.edu)
  • For humans, vitamin A is obtained through the diet, where provitamin A carotenoids such as β-carotene from plants or preformed vitamin A such as retinyl esters from animal sources are absorbed into the body via the small intestine and converted into all-trans retinol within the intestinal enterocytes. (umn.edu)
  • Carotenoids are provitamins of vitamin A. Carotenoids widely distributed in plants, particularly a -, b -, and g -carotene. (tdmuv.com)
  • The carotenes have no vitamin A activity but are converted into vitamin A by enzymatic reactions in the intestinal mucosa and the liver. (tdmuv.com)