Bephenium Compounds: Analogs or derivatives of bephenium (N,N-dimethyl-N-(2-phenoxyethyl)benzenemethanaminium).Levamisole: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)Excipients: Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Tablets: Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)Appetite: Natural recurring desire for food. Alterations may be induced by APPETITE DEPRESSANTS or APPETITE STIMULANTS.Illusions: The misinterpretation of a real external, sensory experience.Appetite Regulation: Physiologic mechanisms which regulate or control the appetite and food intake.Eating: The consumption of edible substances.Inventions: A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.Intellectual Property: Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Microtechnology: Manufacturing technology for making microscopic devices in the micrometer range (typically 1-100 micrometers), such as integrated circuits or MEMS. The process usually involves replication and parallel fabrication of hundreds or millions of identical structures using various thin film deposition techniques and carried out in environmentally-controlled clean rooms.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Nanocapsules: Nanometer-sized, hollow, spherically-shaped objects that can be utilized to encapsulate small amounts of pharmaceuticals, enzymes, or other catalysts (Glossary of Biotechnology and Nanobiotechnology, 4th ed).Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Berberis: A plant genus in the family BERBERIDACEAE. The common names of Barberry or Oregon Grape are also used for MAHONIA. The similar-named Bayberry is the unrelated MYRICA. Oregon Grape was classified by Pursh as a Berberis but Nuttall claimed it is different enough to call it a new genus, MAHONIA. Botanists insist on this name while horticulturists stay with Mahonia. They are shrubs with yellow wood and usually three-branched spines at the base of leafstalks. Flowers are yellow, six-petaled and fruit is a berry with one to several seeds. Members contain BERBERINE.Dictionaries, MedicalBerberine: An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Basidiomycota: A phylum of fungi that produce their sexual spores (basidiospores) on the outside of the basidium. It includes forms commonly known as mushrooms, boletes, puffballs, earthstars, stinkhorns, bird's-nest fungi, jelly fungi, bracket or shelf fungi, and rust and smut fungi.Minority Health: The concept covering the physical and mental conditions of members of minority groups.Foramen Ovale, Patent: A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.Cell Wall: The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.Heart Septal Defects, Atrial: Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Candy: Sweet food products combining cane or beet sugars with other carbohydrates and chocolate, milk, eggs, and various flavorings. In the United States, candy refers to both sugar- and cocoa-based confections and is differentiated from sweetened baked goods; elsewhere the terms sugar confectionary, chocolate confectionary, and flour confectionary (meaning goods such as cakes and pastries) are used.Carbolines: A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.Cheese: A nutritious food consisting primarily of the curd or the semisolid substance formed when milk coagulates.Pterocarpans: A group of compounds which can be described as benzo-pyrano-furano-benzenes which can be formed from ISOFLAVONES by internal coupling of the B ring to the 4-ketone position. Members include medicarpin, phaseolin, and pisatin which are found in FABACEAE.Sister Mary Joseph's Nodule: Metastatic lesion of the UMBILICUS associated with intra-abdominal neoplasms especially of the GASTROINTESTINAL TRACT or OVARY.Umbilicus: The pit in the center of the ABDOMINAL WALL marking the point where the UMBILICAL CORD entered in the FETUS.Amantadine: An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.Rimantadine: An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.Adamantane: A tricyclo bridged hydrocarbon.Galaxies: Large aggregates of CELESTIAL STARS; COSMIC DUST; and gas. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)Antiparkinson Agents: Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.CycloheptanesProtons: Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.

Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance. (1/6)

1. The development of resistance to all chemotherapeutic agents increases and needs to be addressed. We are interested in resistance in parasitic nematodes to the anthelmintic levamisole. During studies on methyridine, we found that it gave us a new insight into pharmacological changes associated with levamisole resistance. Initially, electrophysiological investigation using a two-micropipette current-clamp recording technique revealed that methyridine acts as a cholinergic agonist on nematode muscle receptors (Ascaris suum). Methyridine (>30 microm) produced reversible concentration-dependent depolarizations and increases in input conductance. Mecamylamine (30 microm) and paraherquamide (0.3 microm) produced reversible antagonism of the depolarization and conductance responses to methyridine. These observations suggest that methyridine, like acetylcholine and levamisole, gates ion channels on the muscle of parasitic nematodes. 2. The antagonistic effects of dihydro-beta-erythroidine and paraherquamide on methyridine-induced contractions of A. suum muscle flaps were then examined to determine if methyridine showed subtype selectivity for N-subtype (nicotine-sensitive) or L-subtype (levamisole-sensitive) acetylcholine receptors. Dihydro-beta-erythroidine weakly antagonized the effects of methyridine (but had no effect on levamisole responses). The antagonism of methyridine (pA2, 5.9) and nicotine (pA2, 6.1) by paraherquamide was similar, but was less than the antagonism of levamisole (pA2, 7.0). The antagonist profiles suggested that methyridine has a selective action on the N-subtype rather than on the L-subtype. 3. A novel use for a larval inhibition migration assay was made using L3 larvae of Oesophagostomum dentatum. Inhibitory effects of nicotine, levamisole, pyrantel and methyridine on the migration of larvae of levamisole-sensitive (SENS) and levamisole-resistant (LEV-R) isolates were tested at different concentrations. Levamisole and pyrantel (putative L-subtype-selective agonists) concentration-response plots were displaced to the right in LEV-R isolates. Nicotine (an N-subtype-selective agonist) and methyridine produced little shift in concentration-response plots in the LEV-R isolates. Resistance dose ratios were used to calculate the relative selectivity, rhoL, for the L-type receptor (levamisole rhoL=1.0; pyrantel rhoL=0.93; methyridine rhoL=0.17; nicotine rhoL=0.06). These observations reveal an N-subtype-selective action of methyridine and suggest that levamisole resistance may be associated with a loss of the L-subtype, but not the N-subtype receptors. The pharmacology of methyridine suggests an approach for the treatment of levamisole-resistant parasites.  (+info)

Pharmacology of N-, L-, and B-subtypes of nematode nAChR resolved at the single-channel level in Ascaris suum. (2/6)

Pharmacological experiments on Ascaris suum have demonstrated the presence of three (N-, L-, and B-) subtypes of cholinergic receptor mediating contraction of body wall muscle in parasitic nematodes. In the present study, these ionotropic acetylcholine (ACh) receptors (nAChRs) were activated by levamisole and bephenium under patch-clamp conditions and competitively antagonized by paraherquamide and 2-desoxoparaherquamide. A number of recordings exhibited three separate current amplitude levels, indicating the presence of small, intermediate, and large conductance subtypes of receptor. The mean conductance of the small conductance subtype, G25, was 22 +/- 1 pS; the intermediate conductance channel, G35, was 33 +/- 1 pS; and the large conductance channel, G45, was 45 +/- 1 pS. The small channel was not antagonized significantly by paraherquamide and was identified as the N-subtype. The intermediate channel was preferentially activated by levamisole rather than bephenium and antagonized by paraherquamide: the intermediate channel was identified as the L-subtype. The large conductance channel was preferentially activated by bephenium, antagonized more by 2-desoxoparaherquamde than by paraherquamide and was identified as the B-subtype. These observations reveal that the three channel subtypes have different selectivity for cholinergic anthelmintics. The different selectivity of these compounds should be considered when dealing with drug resistant infections.  (+info)

Phenotypic characterization of two Ancylostoma caninum isolates with different susceptibilities to the anthelmintic pyrantel. (3/6)

 (+info)

Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors. (4/6)

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Use of common salt fortified with iron in the control and prevention of anemia--a collaborative study. Report of the Working Group on Fortification of Salt with Iron. (5/6)

The efficacy of salt fortified with iron (FePO4 and NaHSO4) to control anemia was investigated by large scale field trials in three rural areas and one urban area located in different parts of India, each covering a total population of 4000 to 6000. Hb levels were determined before the introduction of the fortified salt and at six monthly intervals thereafter. Iron-fortified salt was acceptable to the population and its consumption for a period of 12 to 18 months was without any untoward effects. At the end of 12 to 18 months of consumption of iron-fortified salt, a significant improvement in the Hb-levels and a significant reduction in the incidence of anemia was observed in all the test areas. In one of the rural areas tested, there was a high incidence of hookworm infestation and iron-fortified salt showed a significant impact on Hb levels even in this area. Deworming concomitant with distribution of iron-fortified salt was shown to have only a marginal additional benefit.  (+info)

The interaction between anthelmintic drugs and histamine in Ascaris suum. (6/6)

1 Piperazine reduced the histamine content of Ascaris suum, yet it greatly increased the uptake of histamine from the surrounding medium, the neuromuscular structures of the nematode preferentially increasing in amount. 2 Bephenium reduced the histamine content of Ascaris and the uptake of histamine from the surrounding medium. However, the relative amount in the neuromuscular structures increased. 3 The flaccid paralysing action of piperazine may thus involve increased histamine absorption whereas the spastic paralysing action of bephenium may be independent of histamine.  (+info)

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Abstract Pyrantel pamoate was administered orally as a single dose in a suspension or chewable tablet to 379 patients with helminth infections. Single doses of oral suspension were administered for 3 consecutive days to 89 patients. A modified Stoll technique and Richie's concentration method were performed twice before treatment and at 10 and 30 days after treatment. In a single dose of about 5 mg per pound of body weight (base activity) the cure rate for ascariasis was 96.7%; the reduction of the egg count in one case not completely cured was 98%. Significant activity was also observed against Necator americanus; however, at the dosages employed, it was not superior to other agents currently in use. No significant activity was noted against Trichuris trichiura. Clinical observation showed that both formulations were well tolerated by the patients. No significant changes attributable to therapy were observed in determinations of hematopoetic, liver, or renal function.
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Pyrantel pamoate, along with all other kinds of de-worming medications, can flush the worms out of the intestines, and the worms exit the body during defecation. It works by making the worm relax its grip on the intestinal wall, allowing it to pass with the stool. It is important to note that Pyrantel only affects worms in the intestine, and does nothing to remove worms encysted in other parts of the cats body, so multiple treatments with Pyrantel are necessary to give the encysted worms time to migrate back to the intestine to be removed. Follow-up de-worming treatments should be given approximately two weeks after the initial treatment. Roundworms are a disgusting and uncomfortable parasite that, while not usually fatally dangerous in cats, can cause serious problems in kittens. Make sure not to forget follow-up treatments, because an infection can spring back very easily from encysted larvae. ...
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... bephenium compounds MeSH D02.092.877.096.333 --- bretylium compounds MeSH D02.092.877.096.333.150 --- bretylium tosylate MeSH ... benzalkonium compounds MeSH D02.675.276.090 --- benzethonium MeSH D02.675.276.102 --- bephenium compounds MeSH D02.675.276.125 ... trialkyltin compounds MeSH D02.691.850.900.910 --- triethyltin compounds MeSH D02.691.850.900.950 --- trimethyltin compounds ... mustard compounds MeSH D02.455.526.728.468 --- mustard gas MeSH D02.455.526.728.650 --- nitrogen mustard compounds MeSH D02.455 ...
This compound is degraded by reductive dechlorination with anaerobic conditions present, with the degradation products such as ... 1960). "The Comparative Efficacy of Bephenium Hydroxynaphthoate and Tetrachloroethylene against Hookworm and other Parasites of ...
Isoquinolines are a class of compounds (benzopyridines) which are used in medical contexts (such as the anesthetic ... Hellgren, U.; Ericsson, Ö.; Aden Abdi, Y.; Gustafsson, L. L. (2003). "Bephenium hydroxynaphthoate". Handbook of Drugs for ... Benzylamine is an organic chemical compound with the condensed structural formula C6H5CH2NH2 (sometimes abbreviated as PhCH2NH2 ... cation in this salt is called benzylammonium and is a moiety found in pharmaceuticals such as the anthelmintic agent bephenium ...
Items listed in bold indicate initially developed compounds of specific groups. #WHO-EM †Withdrawn drugs. ‡Veterinary use ...
The "trivial" name of this compound is triacetonamine. *^ The boiling point of 147° given by these authors for their N,2,2,6,6- ... Two early syntheses of this compound are those of Leonard and Hauck,[6] and Hall.[5] These are very similar in principle: ... with additional data related to several structurally simpler compounds.[3] ...
Trimetaphan is a sulfonium compound and therefore carries a positive charge. Being charged, it cannot cross lipid cell ...
The discovery of the avermectin family of compounds, from which ivermectin is chemically derived, was made by Satoshi Ōmura of ...
"PubChem Compound. Retrieved 6 March 2014.. *^ Sanders KM, Zhu MH, Britton F, Koh SD, Ward SM (February 2012). "Anoctamins and ... Carbachol is a choline carbamate and a positively charged quaternary ammonium compound.[2] It is not well absorbed in the ...
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain. It is also ...
... is a member of the barbiturate class of drugs, which are relatively non-selective compounds that bind to an ... ligand-gated ion channels that are predominantly permeable for cationic ions are blocked by these compounds. For example, ... "Administration and Compounding of Euthanasic Agents". The Hague. Retrieved 2008-07-18 ...
Allyl compounds. *Neuromuscular blockers. *Lethal injection components. Hidden categories: *Template:drugs.com link with non- ...
Quaternary ammonium compounds. *Tetrahydroisoquinolines. *Nicotinic antagonists. *Phenol ethers. *Macrocycles. *Musculoskeletal ...
Chemical articles with multiple compound IDs. *Multiple chemicals in an infobox that need indexing ...
Tricyclic antidepressants (28 compounds with numerous trade names). *Trihexyphenidyl. *Tropicamide[19]. *Antinicotinic agents * ...
... is an antihistamine and anticholinergic of the pyridine chemical class which was developed in the early 1950s. It was sold under the trade names Co-Pyronil and Histadyl EC.[1] It has relatively strong sedative effects, to the extent that its primary use was as a medication for insomnia rather than for its antihistamine action. Together with scopolamine, it was the main ingredient in Sominex, Nytol, and Sleep-Eze. It also provided the sedative component of Excedrin PM. All of these products were reformulated in the late 1970s when methapyrilene was demonstrated to cause liver cancer in rats when given chronically.[2] ...
This compound is degraded by reductive dechlorination with anaerobic conditions present, with the degradation products such as ... 1960). "The Comparative Efficacy of Bephenium Hydroxynaphthoate and Tetrachloroethylene against Hookworm and other Parasites of ...
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain. It is also ...
Determination of antioxidant capacities and biochemical compounds of Berberis vulgaris L. fruits ...
Representative antiparasitic compounds are ivermectin, bephenium, hydroxynaphthoate, praziquantel, nifurtimox, benznidasol, ... Active agents include compounds (therapeutic compounds) for pharmaceutical use, such as human or veterinary use. The active ... Active agents include compounds (therapeutic compounds) for pharmaceutical use, such as human or veterinary use. ... Representative antiviral compounds are protease inhibitors, neuramidinase inhibitors, commercially available compounds, ...
... bephenium compounds MeSH D02.092.877.096.333 --- bretylium compounds MeSH D02.092.877.096.333.150 --- bretylium tosylate MeSH ... benzalkonium compounds MeSH D02.675.276.090 --- benzethonium MeSH D02.675.276.102 --- bephenium compounds MeSH D02.675.276.125 ... trialkyltin compounds MeSH D02.691.850.900.910 --- triethyltin compounds MeSH D02.691.850.900.950 --- trimethyltin compounds ... mustard compounds MeSH D02.455.526.728.468 --- mustard gas MeSH D02.455.526.728.650 --- nitrogen mustard compounds MeSH D02.455 ...
... an organic compound, an organometallic compound, or an inorganic compound, an antimicrobial agent (including antibacterial and ... bephenium, piperazine, dichlorophen, praziquantel, diethylcarbamazine, pyrantel parmoate, hycanthone, pyrivium pamoate, ... Some organic compounds that can be used in accordance with the present invention include, without limitation, polyacrylonitrile ... Bioactive materials also can include drugs such as chemical or biological compounds that can have a therapeutic effect on a ...
This compound is degraded by reductive dechlorination with anaerobic conditions present, with the degradation products such as ... 1960). "The Comparative Efficacy of Bephenium Hydroxynaphthoate and Tetrachloroethylene against Hookworm and other Parasites of ...
A New Approach to Helminthiasis Control: the Use of an Organophosphorous Compound * J. Cerf, A. Lebrun and J. Dierichx ... Bephenium hydroxynaphthoate was given to 17 patients with hemoglobin levels under 8.0 g per 100 ml without any untoward ... Sixty-three adult patients with Ancylostoma duodenale infection were treated with a single 2.5-gram dose of bephenium ... Treatment of Hookworm Infection in Egypt with Bephenium Hydroxynaphthoate and the Relationship between Iron Deficiency Anemia ...
Instructions to calculate molar mass (molecular weight) of a chemical compound:. To calculate molar mass of a chemical compound ... Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator ... What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the ... Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B- ...
A61K9/1629-Organic macromolecular compounds * A61K9/1635-Organic macromolecular compounds obtained by reactions only involving ... antiparasitics such as bephenium, hydroxynaphthoate, dichlorophen and dapsone; and neoplastics such as nechlorethamine, uracil ... The osmotic pressure of saturated solutions of various osmotically effective compounds and for mixtures of compounds at 37° C ... Use of analgesic potentiating compounds to potentiate the analgesic properties of an analgesic compound ...
A61K31/33-Heterocyclic compounds * A61K31/395-Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, ... hydroxynaphthoate bephenium, cambendazole, dichlorophen, ivermectin, mebendazole, oxamniquine, oxfendazole, oxantel pamoate, ... A61K31/33-Heterocyclic compounds * A61K31/395-Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, ... A61K31/33-Heterocyclic compounds * A61K31/395-Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, ...
Bephenium Compounds/therapeutic use , Hookworm Infections/drug therapy , Humans , Iodine/adverse effects , Thymol/adverse ...
Nouns with 27 letters. Full list of words with these elements: oesophagogastroduodenoscopy, ethylenediaminetetraacetate, electromagnetic interaction, double replacement reaction, gross vehicle weight rating, phosphoribosylpyrophosphate, glucocorticosteroidogenesis...
Suitable transporting aids may be found among lower organic compounds having generally from about 4 to 15 carbons. Exemplary ... antiparasitic agents such as bephenium hydroxynaphthoate and dichlorophen, dapsone and the like; neoplastic agents such as ...
Anthracyclines and related compounds. *Anthracyclines-liposomal formulations. *Anthrax vaccine. *Antiandrogens. *Antianginal ...
The osmotically effective compounds that can be used for the purpose of the invention include inorganic and organic compounds ... antiparasitics such as bephenium, hydroxynaphthoate, dichlorophen and dapsone; and neoplastics such as nechlorethamine, uracil ... The osmotically effective compounds are known also as osmotically effective solutes, or osmagents. The compounds are used by ... The osmotic pressure of saturated solutions of various osmotically effective compounds and for mixtures of compounds at 37. ...
ACARICIDES see Appendix B use NAFTALOFOS use BEPHENIUM HYDROXY NAPHTHOATE TOPOISOMERASE-INHIBITORS h. 2). CARDIANTS UTEROTONICS ... Controlled release of biologically active compounds from bioerod- ible polymers, Biomaterials, 1, or bubble of fluid. Prozac et ... as well as prрzac review proz ac retrial of the older compounds. ...
Items listed in bold indicate initially developed compounds of specific groups. #WHO-EM †Withdrawn drugs. ‡Veterinary use ...
Benzylisoquinolium compound (substance) {442296001 , SNOMED-CT } Bephenium (substance) {391836008 , SNOMED-CT } Bephenium ... Quaternary ammonium compound (substance) {301712000 , SNOMED-CT } Parent/Child (Relationship Type) Acylcarnitine (substance) { ... Drug allergen (substance) {406463001 , SNOMED-CT } Organic nitrogen compound (substance) {299979007 , SNOMED-CT } ... Quaternary ammonium compound with anticholinergic mechanism of action (substance) {108659006 , SNOMED-CT } Quaternary ammonium ...
Product containing benzylisoquinolium compound (product) {766898008 , SNOMED-CT } Product containing bephenium (medicinal ... Quaternary ammonium compound product Current Synonym true false 3672400013 Product containing quaternary ammonium compound ... Product containing quaternary ammonium compound (product) {765420008 , SNOMED-CT } Parent/Child (Relationship Type) Product ... Product containing quaternary ammonium compound (product). Code System Preferred Concept Name. Product containing quaternary ...
... an explosive compound rendered safe when compounded in tablets with mannitol.. CSP. In medicine, a substance used as a drug to ... Analogs or derivatives of bephenium (N,N-dimethyl-N-(2-phenoxyethyl)benzenemethanaminium).. MSH ... A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has ... A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a ...
Side resistance to other compounds in the same chemical group may occur. This is observed in the benzimidazole group of ...
Tag: Ethoxy Carbonyl Phenyl Propyl Alanine 99% , Ecppa Enalapril Impurity B Epal Quinapril , Moexipril Related Compound F ... bephenium.... ... Chemical Compound Sex Chemical Name: (1R,3R)-METHYL-1,2,3,4- ...
DEC is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic ... piperazine (piperazine · diethylcarbamazine#) · thiazole (levamisole#) · quinolinium (pyrvinium) · benzylammonium (bephenium ...
... compounds libraries, compounds inflammation that bind to basement from membrane after degradation endoglin tumors, D ... bephenium naphtoate, bepiastine, bepridil, beraprost, berberine sulfate, bermastine, bermoprofen, berythromycin, besulpamide, ... Thus, the therapeutic compound may be linked to a part of the wall, for example through covalent or ionic bonds, or may be ... Incorporation of compounds from b) and from c) into the bubbles was confirmed by MALDI-MS as follows. Ca. 50 .mu.l of ...
The discovery of the avermectin family of compounds, from which ivermectin is chemically derived, was made by a team of ... piperazine (piperazine · diethylcarbamazine#) · thiazole (levamisole#) · quinolinium (pyrvinium) · benzylammonium (bephenium ...
Bephenium hydroxynaphthoate at 25 mg/kg and Disophenol at 3 mg/kg were found to be effective only in 79.1 to 92.2 %, 88.1 to ...
  • Bephenium hydroxynaphthoate at 25 mg/kg and Disophenol at 3 mg/kg were found to be effective only in 79.1 to 92.2 %, 88.1 to 100%, 84.6 to 95.3 %, 85.9 to 100% and 68.3 to 84 % cases respectively. (elephantcare.org)
  • DEC is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. (meddic.jp)
  • It is the organic compound 1-adamantylamine or 1-aminoadamantane , meaning it consists of an adamantane backbone that has an amino group substituted at one of the four methyne positions. (hitchhikersgui.de)
  • Apart from medical uses, this compound is useful as a building block in organic synthesis, allowing the insertion of an adamantyl group . (hitchhikersgui.de)
  • These systems are extraordinarily effective for delivering a drug that is soluble in the fluid, and also for delivering a drug that has limited solubility in the fluid and is mixed with an osmotically effective compound that is soluble in the fluid and exhibits an osmotic pressure gradient across the wall against the fluid. (justia.com)
  • The osmotic systems release drug by fluid being imbibed through the semipermeable wall into the reservoir at a rate determined by the permeability of the semipermeable wall and the osmotic pressure gradient across the wall producing a solution of soluble drug, or a solution of soluble compound containing drug, which solution in either operation is delivered at a controlled rate over a prolonged period of time. (justia.com)