Benzyl compounds are organic substances that contain a benzyl group, which is a functional structure consisting of a carbon atom attached to a phenyl ring and a methylene group (-CH2-).
A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.
1,1'-Bis(phenylmethyl)4,4'-bipyridinium dichloride. Oxidation-reduction indicator.
Organic compounds with the general formula R-NCS.
Benzaldehydes are aromatic organic compounds consisting of a benzene ring connected to a formyl group (-CHO), which is the simplest and most representative compound being benzaldehyde (C6H5CHO).
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Binding partners for the myelin-associated glycoprotein of N2A neuroblastoma cells. (1/302)

The myelin-associated glycoprotein (MAG) has been proposed to be important for the integrity of myelinated axons. For a better understanding of the interactions involved in the binding of MAG to neuronal axons, we performed this study to identify the binding partners for MAG on neuronal cells. Experiments with glycosylation inhibitors revealed that sialylated N-glycans of glycoproteins represent the major binding sites for MAG on the neuroblastoma cell line N2A. From extracts of [3H]glucosamine-labelled N2A cells several glycoproteins with molecular weights between 20 and 230 kDa were affinity-precipitated using immobilised MAG. The interactions of these proteins with MAG were sialic acid-dependent and specific for MAG.  (+info)

Polynucleotides. XLII1. Limited addition of 2'O-onitrobenzyl nucleotides to the 3'-end of ribooligonucleotide with polynucleotide phosphorylase. (2/302)

2'-O-o-Nitrobenzyluridine, -cytidine and -adenosine were phosphorylated with phosphoryl chloride to the corresponding 5'-phosphates and led to 5'-diphosphates by the method of Moffatt and Khorana. These 2'-O-oNB-nucleoside 5'-diphosphates were incubated with a primer CpApA and polynucleotide phosphorylase in the presence of Mn2+. Tetranucleotides CpApApU, CpApApC and CpApApA were obtained after photosensitive removal of oNB groups in yields of 54-70%.  (+info)

O-linked glycans mediate apical sorting of human intestinal sucrase-isomaltase through association with lipid rafts. (3/302)

The plasma membrane of polarised epithelial cells is characterised by two structurally and functionally different domains, the apical and basolateral domains. These domains contain distinct protein and lipid constituents that are sorted by specific signals to the correct surface domain [1]. The best characterised apical sorting signal is that of glycophosphatidylinositol (GPI) membrane anchors [2], although N-linked glycans on some secreted proteins [3] and O-linked glycans [4] also function as apical sorting signals. In the latter cases, however, the underlying sorting mechanisms remain obscure. Here, we have analysed the role of O-glycosylation in the apical sorting of sucrase-isomaltase (SI), a highly polarised N- and O-glycosylated intestinal enzyme, and the mechanisms underlying this process. Inhibition of O-glycosylation by benzyl-N-acetyl-alpha-D-galactosaminide (benzyl-GalNAc) was accompanied by a dramatic shift in the sorting of SI from the apical membrane to both membranes. The sorting mechanism of SI involves its association with sphingolipid- and cholesterol-rich membrane rafts because this association was eliminated when O-glycosylation was inhibited by benzyl-GaINAc. The results demonstrate for the first time that O-linked glycans mediate apical sorting through association with lipid rafts.  (+info)

Effects of ethyl and benzyl analogues of spermine on Escherichia coli peptidyltransferase activity, polyamine transport, and cellular growth. (4/302)

Various ethyl and benzyl spermine analogues, including the anticancer agent N1,N12-bis(ethyl)spermine, were studied for their ability to affect the growth of cultured Escherichia coli cells, to inhibit [3H]putrescine and [3H]spermine uptake into cells, and to modulate the peptidyltransferase activity (EC 2. 3. 2. 12). Relative to other cell lines, growth of E. coli was uniquely insensitive to these analogues. Nevertheless, these analogues conferred similar modulation of in vitro protein synthesis and inhibition of [3H]putrescine and [3H]spermine uptake, as is seen in other cell types. Thus, both ethyl and benzyl analogues of spermine not only promote the formation and stabilization of the initiator ribosomal ternary complex, but they also have a sparing effect on the Mg2+ requirements. Also, in a complete cell-free protein-synthesizing system, these analogues at low concentrations stimulated peptide bond formation, whereas at higher concentrations, they inhibited the reaction. The ranking order for stimulation of peptide-bond formation by the analogues was N4,N9-dibenzylspermine > N4, N9-bis(ethyl)spermine congruent with N1-ethylspermine > N1, N12-bis(ethyl)spermine, whereas the order of analogue potency regarding the inhibitory effect was inverted, with inhibition constant values of 10, 3.1, 1.5, and 0.98 microM, respectively. Although the above analogues failed to interact with the putrescine-specific uptake system, they exhibited high affinity for the polyamine uptake system encoded by the potABCD operon. Despite this fact, none of the analogues could be internalized by the polyamine transport system, and therefore they could not influence the intracellular polyamine pools and growth of E. coli cells.  (+info)

Distribution of end-to-end distances of oligopeptides in solution as estimated by energy transfer. (5/302)

A homologous series of oligopeptides each containing at its ends a donor and an acceptor of electronic excitation energy was synthesized by the solid-phase method. N-5-(2-Hydroxyethyl)-L-glutamine was the repeating unit, and peptides containing 4, 5, 6, 7, 8, and 9 of these amino-acid residues were prepared. The chromophores naphthalene and dansyl, which were used as donor and acceptor, respectively, fulfil the conditions necessary for energy transfer according to the Forster mechanism. A distance corresponding to 50% efficiency of energy transfer, tro = 22 plus or minus 1 A, was calculated. The kinetics of fluorescence decay of an oligomer containing the naphthalene chromophore only could be described precisely by a monoexponential function. In contrast, the kinetics of the decay curves of the fluorescence of the donor of all of the oligomers containing both donor and acceptor, as measured in viscous solution, deviated markedly from monoexponential behavior. The deviation was interpreted in terms of the great number of different conformations that the various molecules of each of the oligomers attain in solution, leading to characteristic end-to-end distribution functions between the donor and acceptor. Numerical adjustment of the parameters of some of the previously proposed expressions to describe the end-to-end distribution enabled the reconstruction of the kinetics of the fluorescence decay of the donor with great precision. The end-to-end distribution functions for the various oligopeptides were thus evaluated.  (+info)

The matrix metalloproteinase inhibitor BB-1101 prevents experimental autoimmune uveoretinitis (EAU). (6/302)

EAU is characterized by breakdown of the blood-retinal barrier and extravasation of leucocytes into retinal tissue leading to destruction of photoreceptor cells. Matrix metalloproteinases (MMP) have been implicated in trafficking of cells into tissues, but their role in inflammatory eye disease is unclear. A synthetic MMP inhibitor, BB-1101, was administered subcutaneously, from either day 0 or day 7, to Lewis rats challenged with bovine S-antigen to induce EAU. When given up to day 14, BB-1101 reduced the incidence of disease and delayed the day of onset of clinical disease. When administered from day 7 until day 21, EAU was completely abrogated. A quantitative polymerase chain reaction (PCR) assay showed an increase of both matrilysin (MMP-7), neutrophil collagenase (MMP-8) and macrophage metalloproteinase (MMP-12) in retinas from EAU animals compared with naive controls. These enzymes are produced by activated leucocytes and act on components of the basement membrane. These results therefore implicate these MMP as integral to the development of pathology in EAU.  (+info)

Soluble TNF-alpha receptors bind and neutralize over-expressed transmembrane TNF-alpha on macrophages, but do not inhibit its processing. (7/302)

Tumor necrosis factor alpha (TNF-alpha) is initially synthesized as a type II integral membrane protein (transmembrane TNF-alpha) after macrophage activation. In this study we have investigated some aspects of the regulation of expression and biological activity of transmembrane TNF-alpha by both soluble TNF-alpha receptors (sTNF-alphaR) and inhibitors of TNF-alpha processing. We show, using the technique of receptor-mediated ligand precipitation (RMLP), that a dimeric construct of the type I sTNF-alphaR binds to transmembrane TNF-alpha, expressed on the mouse macrophage cell line RAW264.7, under cell culture conditions. This interaction between sTNF-alphaR and transmembrane TNF-alpha does not prevent processing and release of soluble TNF-alpha. A specific hydroxamic acid-based inhibitor of processing, BB1101 (British Biotech), was found to increase the total cellular levels of whole-cell, 26-kDa, precursor TNF-alpha by 2.2-fold. However, the inhibitor increased the levels of precursor TNF-alpha present solely on the cell surface (i.e., transmembrane TNF-alpha) by 5.1- to 7.5-fold. This increase in the levels of transmembrane TNF-alpha on the activated human monocytoid cell line mono mac 6 was associated with a similar (6.7-fold) increase in TNF-alpha-mediated cytotoxicity toward the human adenocarcinoma cell line Colo 205, which is sensitive only to the transmembrane form of TNF-alpha. Mono mac 6 cells, expressing transmembrane TNF-alpha, were found to be killing the Colo 205 target cells through apoptosis. This cytotoxicity could be neutralized by pre-incubating the mono mac 6 cells with either sTNF-alphaR or polyclonal anti-TNF-alpha serum.  (+info)

Combined effects of dissociable and undissociable local anesthetics upon ATP-induced firefly bioluminescence. (8/302)

Combined effects of two drugs present simultaneously are usually expressed as summation, synergism or potentiation, and antagonism. When the sum of the effects of each drug present separately equals the combined effect of the two drugs present simultaneously, the action is called additive or summation. However, the expected value of the sum of each effect of drugs present alone has not been well defined. In this report, the thearetical value of the expected sum of each effect of two inhibitors is given and a graphical method is presented to visualize summation, synergism, and antagonism. The inhibitory effects of a dissociable local anesthetic, tetracaine, and an undissociable local anesthetic, benzyl alcohol, upon a soluble firefly luminescent system were analyzed according to the above theory. The results clearly indicate that the action of these two classes of local anesthetics is pure additive or summation.  (+info)

Benzyl compounds are organic chemical compounds that contain a benzyl group, which is a functional group consisting of a carbon atom attached to a CH3 group (methyl group) and an aromatic ring, usually a phenyl group. The benzyl group can be represented as -CH2-C6H5.

Benzyl compounds have various applications in different fields such as pharmaceuticals, flavors, fragrances, dyes, and polymers. In pharmaceuticals, benzyl compounds are used as active ingredients or intermediates in the synthesis of drugs. For example, benzylpenicillin is a widely used antibiotic that contains a benzyl group.

Benzyl alcohol, benzyl chloride, and benzyl acetate are some common examples of benzyl compounds with various industrial applications. Benzyl alcohol is used as a solvent, preservative, and intermediate in the synthesis of other chemicals. Benzyl chloride is an important chemical used in the production of resins, dyes, and pharmaceuticals. Benzyl acetate is used as a flavoring agent and fragrance in food and cosmetic products.

It's worth noting that benzyl compounds can be toxic or harmful if ingested, inhaled, or come into contact with the skin, depending on their chemical properties and concentrations. Therefore, they should be handled with care and used under appropriate safety measures.

Benzyl alcohol is a aromatic alcohol with the chemical formula C6H5CH2OH. It is a colorless liquid with a characteristic, mildly unpleasant odor. Benzyl alcohol is used as a solvent and as an intermediate in the production of other chemicals. In medicine, it is used as a local anesthetic and antimicrobial agent. It can be found in some personal care products, such as cosmetics, shampoos, and sunscreens, as well as in topical medications and intravenous medications.

Benzyl alcohol is an aromatic alcohol with the chemical formula C6H5CH2OH. It is a colorless liquid with a mild, pleasant odor and is used as a solvent and preservative in cosmetics, medications, and other products. Benzyl alcohol can also be found as a natural component of some essential oils, fruits, and teas.

Benzyl alcohol is not typically considered a "drug" or a medication, but it may have various pharmacological effects when used in certain medical contexts. For example, it has antimicrobial properties and is sometimes used as a preservative in injectable medications to prevent the growth of bacteria and fungi. It can also be used as a local anesthetic or analgesic in some topical creams and ointments.

It's important to note that benzyl alcohol can be harmful or fatal to infants and young children, especially when it is used in high concentrations or when it is introduced into the body through intravenous (IV) routes. Therefore, it should be used with caution in these populations and only under the guidance of a healthcare professional.

Benzyl viologen is a type of chemical compound that belongs to the class of viologens, which are derivatives of the parent compound methylviologen. The chemical name for benzyl viologen is N,N'-diphenyl-4,4'-bipyridinium dichloride.

Viologens are reduced forms of heterocyclic aromatic amines that can undergo reversible reduction and oxidation reactions. In their reduced form, they act as strong reducing agents, while in their oxidized form, they act as strong oxidizing agents. Benzyl viologen is commonly used as an electron carrier or mediator in various chemical and biological systems, such as redox reactions, photochemical processes, and bioelectrochemical devices like fuel cells and biosensors.

The compound consists of two benzyl groups attached to the nitrogen atoms of a bipyridinium cation, which is then complexed with chloride ions. The reduction potential of benzyl viologen is around -0.45 V vs. standard hydrogen electrode (SHE), making it a useful electron carrier in various applications where an easily reducible and oxidizable compound is required.

It's worth noting that while benzyl viologen has potential uses in scientific research, it may also have toxic effects on living organisms, so appropriate safety precautions should be taken when handling this chemical.

Isothiocyanates are organic compounds that contain a functional group made up of a carbon atom, a nitrogen atom, and a sulfur atom, with the formula RN=C=S (where R can be an alkyl or aryl group). They are commonly found in cruciferous vegetables such as broccoli, brussels sprouts, and wasabi. Isothiocyanates have been studied for their potential health benefits, including their anticancer and anti-inflammatory properties. However, they can also be toxic in high concentrations.

Benzaldehyde is an organic compound with the formula C6H5CHO. It is the simplest aromatic aldehyde, and it consists of a benzene ring attached to a formyl group. Benzaldehyde is a colorless liquid with a characteristic almond-like odor.

Benzaldehyde occurs naturally in various plants, including bitter almonds, cherries, peaches, and apricots. It is used in many industrial applications, such as in the production of perfumes, flavorings, and dyes. In addition, benzaldehyde has been used in medical research for its potential therapeutic effects, such as its anti-inflammatory and antimicrobial properties.

However, it is important to note that benzaldehyde can be toxic in high concentrations and may cause irritation to the skin, eyes, and respiratory system. Therefore, it should be handled with care and used in accordance with appropriate safety guidelines.

Molecular structure, in the context of biochemistry and molecular biology, refers to the arrangement and organization of atoms and chemical bonds within a molecule. It describes the three-dimensional layout of the constituent elements, including their spatial relationships, bond lengths, and angles. Understanding molecular structure is crucial for elucidating the functions and reactivities of biological macromolecules such as proteins, nucleic acids, lipids, and carbohydrates. Various experimental techniques, like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM), are employed to determine molecular structures at atomic resolution, providing valuable insights into their biological roles and potential therapeutic targets.

"Compounds Affecting the Central Nervous System. IV. Substituted 2-Benzyl-3-dialkylaminoalkylindenes and Related Compounds". ... 1-Indanone is the organic compound with the formula C6H4(CH2)2CO. It is one of two isomeric benzocyclopentanones, the other ...
The compound is a reagent for introducing benzyl groups. Benzyl bromide can be synthesized by the bromination of toluene under ... Benzyl chloride Benzyl fluoride Benzyl iodide Merck Index (11th ed.). p. 1142. "Benzyl bromide_msds". William E. Bauta (2001 ... Benzyl bromide is used in organic synthesis for the introduction of the benzyl groups when the less expensive benzyl chloride ... Benzyl bromide is an organic compound with the formula C6H5CH2Br. The molecule consists of a benzene ring substituted with a ...
This compound can be classified as a benzyl halide. Xylylene dichloride is used as a vulcanizing agent to harden rubbers. It ... The chemical compound xylylene dichloride (C6H4(CH2Cl)2) is a white to light yellow sandlike solid. ... Xylylene dibromide, the dibromo analogue of the title compound. Xylylene dichloride. New Jersey Department of Health and Senior ... Chemical articles with multiple compound IDs, Chemicals using indexlabels, Chemical articles with multiple CAS registry numbers ...
... is an organosulfur compound with the formula C6H5CH2SH. It is a common laboratory alkylthiol that occurs in ... Benzyl mercaptan can be prepared by the reaction of benzyl chloride and thiourea. The initially formed isothiouronium salt must ... CH3C6H5 Condensed tannins undergo acid-catalyzed cleavage in the presence of benzyl mercaptan. Methoxy-substituted benzyl ... Benzyl mercaptan is used for S-alkylation to give benzylthioethers. It has been used as a source of the thiol functional group ...
Chemical compounds in the scent include benzyl acetate and benzaldehyde. Silene nutans is the host plant for the leaf mining ...
The compound can be viewed as the ester of carbamic acid (O=C(OH)(NH2)) and benzyl alcohol, although it is produced from benzyl ... Benzyl carbamate is the organic compound with the formula C6H5CH2OC(O)NH2. ... Benzyl carbamate is used as a protected form of ammonia in the synthesis of primary amines. After N-alkylation, C6H5CH2OC(O) ... Sanchez-Sancho, Francisco; Romero, Jose Antonio; Fernandez-Ibanez, M. Angeles (2010). "Benzyl Carbamate". E-EROS Encyclopedia ...
This fragment is often found for aromatic compounds containing a benzyl unit. Upon ionization, the benzyl fragment forms a ... Unlike most alkyl bromides, this compound, later named tropylium bromide, is water-soluble but insoluble in many organic ... In 1891 G. Merling obtained a water-soluble bromine-containing compound from the reaction of cycloheptatriene and bromine. ...
... the compound has the high refractive index of 1.6334. Benzyl iodide is also a powerful lachrymator. Benzyl bromide Benzyl ... Benzyl iodide is an organic compound with the chemical formula C 7H 7I. The compound consists of a benzene ring with an ... Benzyl iodide can be obtained via the Finkelstein reaction from benzyl chloride and sodium iodide in acetone. Benzyl iodide ... chloride Benzyl fluoride "BENZYL IODIDE". chemicalbook.com. Retrieved 8 June 2017. "Benzyl iodide". NIST. webbook.nist.gov. ...
This reagent reacts with toluene to form the red-orange compound benzyl potassium (KCH2C6H5). Evidence for the formation of ... These compounds can be prepared by treatment of alkyl lithium compounds with the potassium, rubidium, and caesium alkoxides. ... The application of organosodium compounds in chemistry is limited in part due to competition from organolithium compounds, ... In the original work the alkylsodium compound was accessed from the dialkylmercury compound by transmetallation. For example, ...
... is an organic compound which is used as a medication and insect repellent. As a medication it is used to treat ... It is an organic compound with the formula C6H5CH2O2CC6H5. It is the ester of benzyl alcohol and benzoic acid. It forms either ... Benzyl benzoate is produced industrially by the reaction of sodium benzoate with benzyl chloride in the presence of a base, or ... Benzyl benzoate has low acute toxicity in laboratory animals. It is rapidly hydrolyzed to benzoic acid and benzyl alcohol. ...
... (abbreviated BnCN) is an organic compound with the chemical formula C6H5CH2CN. This colorless oily aromatic ... Benzyl cyanide is regulated in the United States as a DEA List I chemical. Benzyl cyanide is regulated in People's Republic of ... Benzyl cyanide can be produced via Kolbe nitrile synthesis between benzyl chloride and sodium cyanide and by oxidative ... Benzyl cyanide, like related benzyl derivatives, is an irritant to the skin and eyes. Bromobenzyl cyanide Nomenclature of ...
... is an organic compound consisting of a benzene ring substituted with a fluoromethyl group. Benzyl chloride ... Benzyl compounds, All stub articles, Organic compound stubs). ... Benzyl bromide Benzyl iodide CRC Handbook of Chemistry and ... Edition, CRC Press, Boca Raton, Florida, 2009, ISBN 978-1-4200-9084-0, Section 3, Physical Constants of Organic Compounds, p. 3 ...
... is the chemical compound which is the ester derived from cinnamic acid and benzyl alcohol. Benzyl cinnamate ... Benzyl cinnamate can be prepared by heating benzyl chloride and excess sodium cinnamate in water to 100-115 °C or by heating ... "Benzyl cinnamate". Sigma-Aldrich. George A. Burdock (2010), "BENZYL CINNAMATE", Fenaroli's Handbook of Flavor Ingredients (6th ... Benzyl cinnamate is used in heavy oriental perfumes and as a fixative. It is used as a flavoring agent. It is used ...
Other compounds are: benzoic acid, benzyl alcohol, borneol, o-cresol, 4-(4'-hydroxyphenyl)-2-butanone, hydroquinone, phenol. ... At least 24 compounds are known constituents of beaver castoreum. Several of these have pheromonal activity, of which the ... All those compounds are gathered from plant food. It also contains nupharamine alkaloids and castoramine, and cis-cyclohexane-1 ... Five additional compounds elicit a weaker response: 4-methylcatechol, 4-methoxyacetophenone, 5-methoxysalicylic acid, ...
This provided a method of producing substituted benzyl compounds with interesting results, such as a synthesis of anthracene. ... He also did considerable work on the derivatives of o-quinone, although he missed the discovery of the parent compound by only ... In 1875 after returning to Harvard Jackson synthesized the first new organic compound made in a Harvard laboratory, p- ... In the following years he developed syntheses of flavoring compounds curcumin and vanillin. He also synthesised benzine tri- ...
In the next two steps, the benzyl protecting group in compound 41 was replaced by an acetyl group. Carbonate ester 43 was ... Enol triflate 38 resulted from a rearrangement of compound 31 after protection of its hydroxyl group. Compound 31 was derived ... This compound is commercially available as a single enantiomer and the single chiral group present in this molecule is able to ... Compound 49 was ultimately derived from the Heck reaction of enol triflate 38, which was used to close the B-ring. ...
This compound then initiates an SN2 reaction to displace the benzyl halide. Unlike in the nitroaldol reaction, where the ... Although originally developed for benzyl compounds, the reaction also works for allyl halides, giving the respective α,β-enones ... The O-benzyl structure then undergoes a pericyclic reaction to produce a benzaldehyde, with dimethyloxime as a byproduct. ... ISBN 978-0-471-70450-8. Hass, Henry B.; Bender, Myron L. (1949). "The Reaction of Benzyl Halides with the Sodium Salt of 2- ...
... , or α-chlorotoluene, is an organic compound with the formula C6H5CH2Cl. This colorless liquid is a reactive ... Benzyl ethers are often derived from benzyl chloride. Benzyl chloride reacts with aqueous sodium hydroxide to give dibenzyl ... Benzyl bromide Benzyl fluoride Benzyl iodide List of highly toxic gases NIOSH Pocket Guide to Chemical Hazards. "#0053". ... Benzyl chloride was first prepared from treatment of benzyl alcohol with hydrochloric acid. Industrially, benzyl chloride is ...
... (veratryl alcohol) is an organic compound related to veratrole and also to benzyl alcohol. It can be obtained ... CRC Handbook of Tables for Organic Compound Identification, Third Edition, 1984, ISBN 0-8493-0303-6. Hermann Kämmerer, V.; ...
... , or 1,3-diphenylacetone, is an organic compound composed of two benzyl groups attached to a central carbonyl ... Benzyl compounds, All stub articles, Ketone stubs). ...
Ultimately, PhABCG1 is responsible for the protein-mediated transport of volatile organic compounds, such as benzyl alcohol and ... In general, volatile compounds may promote the attraction of seed-dispersal organisms and pollinators, as well as aid in ... In these transgenic lines, a decrease in emission of volatile compounds was observed. Thus, PhABCG1 is likely involved in the ... Adebesin, Funmilayo (June 30, 2017). "Emission of volatile organic compounds from petunia flowers is facilitated by an ABC ...
... is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics as a fragrance ... ISBN 0-931710-37-5 "Benzyl salicylate". The Good Scents Company. Belsito, D; Bickers, D; Bruze, M; Calow, P; Greim, H; Hanifin ... An Introduction to Perfumery by Curtis & Williams 2nd Edition, 2009, ISBN 978-0-9608752-8-3, ISBN 978-1-870228-24-4 Benzyl ...
... or N,N-Dibenzylaniline is a chemical compound consisting of aniline with two benzyl groups as substituents on ... This then reacts with benzyl bromide to yield dibenzylaniline. Another method uses aniline and benzyl bromide. It used to make ... N-benzilideneaniline along with hexamethylphosphoric triamide dissolved in tetrahydrofuran which yields a tin amide compound. ...
In the presence of UV light, oxidation of this polymer yields compounds such as ketones, phenols, o-phenoxybenzoic acid, benzyl ... BPA is a compound that is currently on the list of potential environmental hazardous chemicals. It is on the watch list of many ... Phenol derivatives are environmental pollutants, classified as volatile organic compounds (VOC). Studies show they are likely ... n This product can be further oxidized to form smaller unsaturated compounds. This can proceed via two different pathways, the ...
... is an organic compound with the formula C6H4(CH2Br)2. It is an off-white solid that, like other benzyl ... Xylylene dichloride, the dichloro analogue of the title compound. Benzyl bromide, the simplest benzylic bromide. Bornstein, J ...
Organic compound stubs, Benzyl compounds, Glucosides, Disaccharides). ... Benzyl gentiobioside is a decyanogenated form of amygdalin. Benzyl gentiobioside occurs in Prunus persica seeds. Del Cueto, ...
... compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules". Journal of ... 1-Benzyl-4-[2-(diphenyl​methoxy)​ethyl]​piperidine is a stimulant of the piperidine class which acts as a potent and selective ...
... (BBP) is an organic compound historically used a plasticizer, but which has now been largely phased out ... First of all, it can be taken up dermally, meaning that the compound is absorbed by the skin. Studies in rats show that 27% of ... While a major part of the BBP is excreted as a mono-benzyl phthalate metabolite, a minor fragment of the BBP is excreted in the ... It is a phthalate ester of containing benzyl alcohol, and n-butanol tail groups. Like most phthalates, BBP is non-volatile and ...
Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, ECHA InfoCard ID from ... E.g. benzyl benzoate, benzyl salicylate, benzyl cinnamate, dibenzyl ether, benzyl butyl phthalate. It can be used as a local ... Benzyl esters also occur naturally. Benzyl alcohol is produced industrially from toluene via benzyl chloride, which is ... The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is ...
Benzylpotassium is an organopotassium compound with the formula C6H5CH2K. It is an orange powder. Like organo-alkali metal ... Although potassium hydride can also be used as a strong base for preparing potassium salts, benzyl potassium has the advantage ... reagents in general, benzyl potassium is highly reactive, so much so that it reacts with most solvents. It is highly air ... Potassium compounds, Benzyl compounds). ...
2-benzyl-5-bromo-isoindoline, , 905274-85-3, NO MDL FOUND
Dimethyl benzyl amine is a ionic compound?. It is slightly basic (as amines are) but it is neutral and not ionic (Cf. NH3) ... Equation in the reactions of benzyl alcohol and sodium metal?. 2 Benzyl alcohol + 2 Na ---> H2(g) + 2 sodium benzoate ... Tags Elements and Compounds Subjects. Animals & Plants Arts & Entertainment Auto Beauty & Health Books and Literature Business ... How safe is Alkyl dimethyl benzyl ammonium saccharinate?. Very, but in high concentration, it can be toxic. But that is highly ...
The compound is a reagent for introducing benzyl groups. Benzyl bromide can be synthesized by the bromination of toluene under ... Benzyl chloride Benzyl fluoride Benzyl iodide Merck Index (11th ed.). p. 1142. "Benzyl bromide_msds". William E. Bauta (2001 ... Benzyl bromide is used in organic synthesis for the introduction of the benzyl groups when the less expensive benzyl chloride ... Benzyl bromide is an organic compound with the formula C6H5CH2Br. The molecule consists of a benzene ring substituted with a ...
Quaternary ammonium compounds, benzyl C12-C16 (even numbered)-alkyldimethyl chlorides. *. *. EC number: 939-253-5 , CAS number ...
Chemical compounds covered are: benzyl chloride; carbon black; furfuryl alcohol; hexachlorocyclopentadiene; hexafluoroacetone; ... Boron compounds; Bromine organic compounds; Cobalt organic compounds; Wood dust; Carbon black; Ozone; Mercury organic compounds ... cobalt and its compounds; fumigants; glycidyl ethers; inorganic azides; inorganic chromium compounds; iron and its compounds; ... Lead organic compounds; Thiols; Nitrides; Anhydrides; Manganese organic compounds; Iron organic compounds; Chromium inorganic ...
Quaternary ammonium compounds, benzyl C12-C16 (even numbered)-alkyldimethyl chlorides 939-253-5 - Active Full Joint ≥ 1 000 to ... Quaternary ammonium compounds, benzyl-C16-C18 (even numbered)-alkyldimethyl, chlorides 939-290-7 - Active Full Joint ≥ 1 000 to ... Quaternary ammonium compounds, benzyl C12-C16 (even numbered)-alkyldimethyl chlorides 939-253-5 - - View substance registered ... Quaternary ammonium compounds, benzyl C12-C16 (even numbered)-alkyldimethyl chlorides 939-253-5 - 2013; 2022 View substance ...
Benzyl 2-propylacrylate , C13H16O2 , CID 16217416 - structure, chemical names, physical and chemical properties, classification ...
a. A substance described in s. 893.03(1)(c)164., 174., or 175., a n-benzyl phenethylamine compound, as described in s. 893.03(1 ... importation would be the death of any person commits capital manufacture or importation of a n-benzyl phenethylamine compound, ... commits a felony of the first degree, which felony shall be known as "trafficking in n-benzyl phenethylamines," punishable as ...
Alkyl, allyl and benzyl derivatives of these mercapto compounds were subsequently prepared. ... Final products were: 1, 3-dimethyl-4-benzyl-, 1-phenyl-3-methyl-4-benzyl-, 1-styryl-3-methyl-4-benzyl- and 1-(3′, 4′, 5′- ... Benzyl and anisyl chlorides were respectively condensed with benzyl methyl ketone to yield α, β-diphenyl and α-phenyl-β-(p- ... Heating the 6-chloro compounds in alcoholic potassium hydroxide solution yielded 5-alcoxy compounds. 2-Benzylamino-4-methyl-6- ...
Combinations of benzyl benzoate and sulfur containing compounds are classified in P03AA.. Dimeticone used as antiflatulent is ...
The bioactive compound reported was benzyl isothiocyanate (42), that had high cytotoxic activity against HL-60 cell with IC50: ... 4-[(α-L-rhamnosyloxy)benzyl]isothiocyanate (34), 4-[(2′-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate (35), 4-[(3′-O-acetyl-α ... About 110 compounds were identified from the genus and are tabulated in Figure 1 and Table 3. Some of these compounds showed ... 4-[(α-L-rhamnosyloxy)benzyl]isothiocyanate (34) and 4-[(4′-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate (37) from M. ...
... a sulfide moiety at the alpha-carbon were synthesized by reaction of the corresponding alpha-alkoxy compounds with benzyl thiol ... Separation of their pure stereoisomers and desulfurization with nickel boride demonstrated that the reduction of such compounds ...
WVDDGKGOMKODPV-UHFFFAOYSA-N benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 6 ... 150000001875 compounds Chemical class 0.000 description 4 * 230000004406 elevated intraocular pressure Effects 0.000 ... CZMRCDWAGMRECN-UGDNZRGBSA-N D-sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C ... PXGPLTODNUVGFL-YNNPMVKQSA-N 9α,11α-PGF2 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O ...
... for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds. De ... Chemical compound and disease context of tocainide. *History of previous myocardial infarction and failure of response to ... for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds [23 ... Associations of tocainide with other chemical compounds. *It seems, however, that mutations of the inactivation gate (ID3-4 ...
Bjerkandera adusta produced aromatic compounds such as benzaldehyde (bitter almond aroma), benzyl alcohol and benzoic acid from ...
Vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) 300 I.U. Compounded with 2% benzyl alcohol (preservative) in a ...
N-benzyl--methylpropylamine , C11H17N , CID 12446306 - structure, chemical names, physical and chemical properties, ...
Hirshfeld surface and frontier mol-ecular orbital analysis of 10-benzyl-9-(3-eth-oxy-4-hy-droxy-phen-yl)-3,3,6,6-tetra-methyl-3 ... The bond lengths in the title compound, are close to those reported for similar compounds, for example, 10-benzyl-9-(3,4-di- ... and 10-benzyl-9-(4-eth-oxy-phen-yl)-3,3,6,6-tetra-methyl-3,4,6,7,9,10-hexa-hydro-acridine-1,8(2H,5H)-dione (Sughanya & ... 10-Benzyl-9-(3-ethoxy-4-hydroxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione top. ...
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds. Symposium Series 2002, Vol. 5, ... Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds. Symposium ... 7-(1-Cyanobut-3-en-1-yl)-N6-[(N,N-dimethylamino)methylene]adenine as a Starting Compound for the Synthesis of α-Branched ... Preparation of aliphatic analogues of S-adenosyl-L-homocysteine and related compounds. 1981, Vol. 46, Issue 12, pp. 3134-3144 [ ...
Chemical compound and disease context of DTPA-SMS. *CONCLUSION: Indium In-111 pentetreotide scintigraphy is a new innovative ... Associations of DTPA-SMS with other chemical compounds. *After intravenous administration of a radiolabeled somatostatin analog ... Pentetreotide 2-[2-[[1-[[10-(4-aminobutyl)- 16-benzyl-4.... Synonyms: AC1LCS5N, LS-187384, D01859, 138661-02-6, UNII-G083B71P98 ... evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound ...
Molecular Orbital Investigations on Lignin Model Compounds. XXI. Solvent Effect on the Stability of β-Aryl Ether and Benzyl ... Influence of Carbohydrates and Related Compounds on the Alkaline Cleavage of the ß-Aryl Ether Linkage in a Phenolic Lignin ... Scanning Electron Microscope Observations of Fungal Associations with Lignin and Insoluble Dimeric Lignin Model Compounds. ... Synthesis of Some Tetrameric Lignin Model Compounds Containing ß-O-4 and 5,5′-Interunit Linkages. ...
PHYSICAL, CHEMICAL, AND PROTOCOL-RELATED HAZARDS 43 sium o-phenylphenate and potassium o-benzyl-p-chlorophenate) and quaternary ... ammonium compounds are also used as disinfectants. Various pesticides can be used within animal facilities, but most animal ...
5) Amphetamine or methamphetamine with a halogen substitution on the benzyl ring, including compounds such as fluorinated ... Any compound, except bupropion or compounds listed under a different schedule, structurally derived from 2-aminopropan-1-one by ... u. Any compound structurally derived from 3-(1-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring to ... v. Any compound structurally derived from 1-(1-naphthylmethyl)indene by substitution at the 3-position of the indene ring to ...
04075 BENZOIN COMPOUND 04088 BENZOYL PEROXIDE 04095 BENZYL 04100 BEROCCA 04105 BEROCCA-CNAMCS 1985 04120 BETADINE 04130 ... 11215 EMPIRIN COMPOUND 11230 EMPIRIN COMPOUND #3 11235 EMPIRIN COMPOUND #4 11240 EMPIRIN COMPOUND W/CODEINE 11245 EMPIRIN NO. 2 ... 50570 BENZYL ALCOHOL 50575 BENZYL BENZOATE 50576 BENZYL CINNAMATE 50578 BERBERINE 50583 BETAINE 50585 BETAMETHASONE 50595 ... 28815 SOMA COMPOUND 28820 SOMA COMPOUND W/ CODEINE 28840 SOMOPHYLLIN 28920 SORBITRATE 29015 SPARINE 29050 SPASTOLATE 41505 ...
Drugs or Compounds in Development. Imaging Agents. Information Aggregators. Journal Publishers via MeSH. ... 7-Benzyl-2,7-diazaspiro[4.5]de. cane *Molecular FormulaC15H22N2 ... 7-Benzyl-2,7-diazas. piro[4.5]decane [ACD/IUPAC Name] 7-Benzyl- ... 7-Benzyl-2,7-diazas. piro[4.5]decan [German] [ACD/IUPAC Name] ... Compounds with the same molecular formula * Compounds with the ...
Drugs or Compounds in Development. Imaging Agents. Information Aggregators. Journal Publishers via MeSH. ... benzyl-α-D-arabinof. uranosid [German] [ACD/IUPAC Name] α-D-Arabinofuranosi. de, methyl 2,3,5-tr. is-O-(phenylmethyl)- [ACD/ ... benzyl-α-D-arabinof. uranoside [ACD/IUPAC Name] Methyl-2,3,5-tri-O-. ... 2,3,5-Tri-O-benzyl-. α-D-arabinofuranosi. de de méthyle [French] [ACD/IUPAC Name] ...
Compounds by Altering Substitutions in the N-Benzyl Moiety and Behavioral Pharmacology of Selected Molecules. Journal of ... GBR Compounds and Mepyramines as Cocaine Abuse Therapeutics: Chemometric Studies on Selectivity Using Grid Independent ... Effects of Two Novel D 3 -Selective Compounds, NGB 2904 [ N -(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)-9 H -fluorene-2- ... Influence of Cocaine History on the Behavioral Effects of Dopamine D3 Receptor-Selective Compounds in Monkeys. ...
A compound of general formula I wherein: Ra is a benzyl, 1-phenylethyl, or 3-chloro-4-fluorophenyl group; Rb is a dimethylamino ... the compound of the formula IV is reduced to generate a compound of the formula V underthe Pd/C catalysis; the compound of the ... the compound of the formula I is subjected to a nitration reaction to synthesize a compound of the formul II; the compound of ... reacts with a compound shown in a formula (5) to produce a compound shown in a formula (3); (b), the compound shown in the ...
Magic Germicide (ABC Compounding) Super Grit ( ABC Compounding). Pine-Sol (Clorox) Lemon-Sol (Clorox) ... Occupational asthma due to indirect exposure to lauryl dimethyl benzyl ammonium chloride used in a floor cleaner. [Burge PS and ... Quaternary ammonium compounds and occupational asthma. [Purohit A, Kopferschmitt-Kubler MC, et al. 2000. Int Arch Occup Environ ... Alkyl dimethyl benzyl ammonium chloride (ADBAC). (Benzalkonium chloride, Dimethylcocobenzalkonium chloride, Quaternary ammonium ...
  • There are a number of chemicals in cleaning and disinfecting products that can cause or exacerbate asthma because of their sensitizing or irritant properties, including quaternary ammonium compounds, ethanolamines, chlorhexidine, glutaraldehyde, ortho-phthalaldehyde, hexachlorophene, and chloramine-T. (cdc.gov)
  • of Benzyl Alcohol and Benzoic Acid. (cosmeticsinfo.org)
  • The CIR Expert Panel reviewed data that indicated that inhalation exposure to Benzyl Alcohol and Benzoic Acid did not result in adverse effects. (cosmeticsinfo.org)
  • A benzethonium is a quaternary ammonium cation, N-benzyl-N,N-dimethyl-2-{2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethanaminium, whose chloride is an industrial disinfectant. (answers.com)
  • Benzyl Chloride is produced from the reaction of Toluene with Chlorine. (gunjanpaints.com)
  • Gunjan Paints guarantees minimum 99.5% Purity (GLC) of Benzyl Chloride. (gunjanpaints.com)
  • Benzalkonium chloride is a quaternary ammonium compound used in pharmaceutical formulations as an antimicrobial preservative in applications similar to other cationic surfactants. (atamankimya.com)
  • Since methylene chloride is a volatile organic compound that will evaporate faster when sprayed, brushed, or poured, the chemical vapors can quickly build up in small spaces. (cdc.gov)
  • Vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) 300 I.U. Compounded with 2% benzyl alcohol (preservative) in a water emulsifiable base. (vedco.com)
  • Arsenic Acid - a colorless chemical compound whose uses are limited by its toxicity, but can be used occasionally as a wood preservative or as a finishing agent for glass or metal. (rubbercal.com)
  • Benzyl Alcohol - a chemical compound used most commonly as a solvent, preservative, or as a precursor for perfume and soap due to its mild pleasant scent. (rubbercal.com)
  • They may be grouped further into aliphatic-chain compounds, such as n -hexane, and as aromatic compounds with a 6-carbon ring, such as benzene or xylene. (medscape.com)
  • Gibbons RJ, Engle LP. Vitamin K compounds in bacteria that are obligate anaerobes. (medscape.com)
  • Disproportionation of benzyl alcohol has been identified as the source of toluene formation in the solvent free oxidation of benzyl alcohol using supported gold palladium catalysts. (southwales.ac.uk)
  • Information profiles on potential occupational hazards of a series of chemical compounds and industrial processes are presented in the form of data sheets describing chemical structures, biological effects, human effects, exposure limits, prevailing standards, etc. (cdc.gov)
  • Quantum chemical calculations for the frontier mol-ecular orbitals were undertake to determine the chemical reactivity of the title compound. (iucr.org)
  • Raw materials and reagents used in the preparation method have the advantages of low cost, stable chemical property and convenience in long-term storage and the content of an impurity cis-isomer in the prepared afatinib compound is very low. (lookchem.com)
  • Acetic Acid 30% - a chemical reagent used in the production of chemical compounds. (rubbercal.com)
  • Acetylene - one of the simplest alkyne compounds and is used as a fuel and chemical building block. (rubbercal.com)
  • Organic solvents are a chemical class of compounds that are used routinely in commercial industries. (medscape.com)
  • Eight heterocyclic compounds and twelve phenolic glycosides were separated from the water extract of Dendrobium officinale flowers through chromatographic techniques, such as Diaion HP-20 macroporous adsorption resin column chromatography(CC), silica gel CC, ODS CC, Sephadex LH-20 CC, and preparative high performance liquid chromatography(PHPLC). (bvsalud.org)
  • Combinations of benzyl benzoate and sulfur containing compounds are classified in P03AA. (whocc.no)
  • and Benzyl Benzoate are also approved as a synthetic flavoring agents for direct addition to food. (cosmeticsinfo.org)
  • The safety of Benzyl Alcohol and Benzyl Benzoate has been evaluated by the Research Institute for Fragrance Materials Expert Panel (REXPAN). (cosmeticsinfo.org)
  • The IFRA standards restrict the use of Benzyl Alcohol and Benzyl Benzoate in fragrances because of potential sensitization. (cosmeticsinfo.org)
  • Benzyl Alcohol and Benzyl Benzoate are also listed in in Annex III of the European Union Cosmetics Directive. (cosmeticsinfo.org)
  • Model amino acid derivatives bearing a sulfide moiety at the alpha-carbon were synthesized by reaction of the corresponding alpha-alkoxy compounds with benzyl thiol and SnCl(4). (rcsb.org)
  • Dimethyl benzyl amine is a ionic compound? (answers.com)
  • Calcium Hydroxide - an inorganic compound that is the result of calcium oxide and water being mixed that is commonly used in the preparation of food. (rubbercal.com)
  • Separation of their pure stereoisomers and desulfurization with nickel boride demonstrated that the reduction of such compounds proceeds with epimerization, in contrast to the previously reported retention of stereochemistry for analogous reaction of steroidal sulfides. (rcsb.org)
  • In one study, 5% Benzyl Alcohol elicited a reaction, and in another study, 2% Benzoic Acid did likewise. (cosmeticsinfo.org)
  • 1-Indanone is the organic compound with the formula C6H4(CH2)2CO. (wikipedia.org)
  • BENZYL ACETATE - Organic compound found in flowers. (hosnani.com)
  • DEHYDROACETIC ACID - An organic compound used in cos- metic preparations for its antibacterial and antifungal proper ties. (hosnani.com)
  • Ammonia Gas (cold) - a compound of nitrogen and hydrogen used in many commercial cleaning products. (rubbercal.com)
  • The invention discloses a preparation method of a quinazolinyl butylene amide compound, which effectively reduces the generation of impurities in the synthesis process by selecting a proper mixed alkali system and using a mixture of 1, 5-diaza-bicyclo [4.3. (lookchem.com)
  • Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl and a carbonyl at the pyrrole ring typically at the 2-position. (bvsalud.org)
  • Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Brain Dopamine Transporter with Positron Emission Tomography. (acs.org)
  • New oxathiazin-like compounds and their derivatives are useful as antineoplastic and antimicrobial agents. (justia.com)
  • Compounds were tested for the activity of decreasing the capillary fragility by the prevention of pulmonary hemorrhage in mice under reduced pressure. (go.jp)
  • Although most of the data regarding the carcinogenicity of these compounds comes from rats and mice, epidemiologic studies have shown increased mortality due to lung and bladder cancer in humans exposed to coke-oven emissions, roofing-tar emissions, and cigarette smoke. (cdc.gov)
  • Biomeasures of phytoestrogens are necessary to establish reference ranges for these compounds and to evaluate their potential effects on human health. (cdc.gov)
  • Among them, compound 1 is a new furfural benzyl alcohol condensate, with the skeleton first found in Dendrobium. (bvsalud.org)
  • Benzyl Alcohol is approved as an anesthetic ingredient in Over-the-Counter (OTC) anorectal, oral healthcare and topical analgesic drug products. (cosmeticsinfo.org)
  • the compound of the formula VI and dimethylamine finally synthesize the compound of the formula VII, that is to say, an afatinib refined product is obtained. (lookchem.com)
  • The kinase inhibitor is a compound represented by formula (I) wherein the groups are defined as described in the description. (justia.com)
  • The compound of formula (I) has a kinase inhibitory activity and therefore can be used for the preparation of medicines for treating kinase activity-related diseases. (justia.com)
  • Because some of these compounds are known to be estrogenic and have been associated with a host of health problems in rats, such as cancers and teratogenicity, governments in Europe and Japan have become increasingly concerned about levels in food packaging materials and children's toys. (cdc.gov)
  • These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (uams.edu)
  • The mol-ecular structure of the title compound, showing the atom-numbering scheme. (iucr.org)
  • Compounds 11 and 14 showed moderate DPPH radical scavenging capacity, and compounds 11-14 demonstrated potent ABTS radical scavenging capacity, possessing antioxidant activity. (bvsalud.org)
  • Many different plants produce compounds called phytoestrogens that mimic or interact with estrogen. (cdc.gov)