A chromogenic substrate that permits direct measurement of peptide hydrolase activity, e.g., papain and trypsin, by colorimetry. The substrate liberates p-nitroaniline as a chromogenic product.
The simplest of all peptides. It functions as a gamma-glutamyl acceptor.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
The rate dynamics in chemical or physical systems.
Venoms from animals of the order Scorpionida of the class Arachnida. They contain neuro- and hemotoxins, enzymes, and various other factors that may release acetylcholine and catecholamines from nerve endings. Of the several protein toxins that have been characterized, most are immunogenic.
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
Arthropods of the order Scorpiones, of which 1500 to 2000 species have been described. The most common live in tropical or subtropical areas. They are nocturnal and feed principally on insects and other arthropods. They are large arachnids but do not attack man spontaneously. They have a venomous sting. Their medical significance varies considerably and is dependent on their habits and venom potency rather than on their size. At most, the sting is equivalent to that of a hornet but certain species possess a highly toxic venom potentially fatal to humans. (From Dorland, 27th ed; Smith, Insects and Other Arthropods of Medical Importance, 1973, p417; Barnes, Invertebrate Zoology, 5th ed, p503)
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis.
Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.
A cysteine endopeptidase isolated from papaya latex. Preferential cleavage at glutamic and aspartic acid residues. EC 3.4.22.6.
A reagent used for the determination of iron.
A sulfhydryl proteinase with cysteine at the active site from ficus latex. Preferential cleavage is at tyrosine and phenylalanine residues. EC 3.4.22.3.
A proteolytic enzyme obtained from Carica papaya. It is also the name used for a purified mixture of papain and CHYMOPAPAIN that is used as a topical enzymatic debriding agent. EC 3.4.22.2.
A plant genus of the family Caricaceae, order Violales, subclass Dilleniidae, class Magnoliopsida. It is the source of edible fruit and PAPAIN.
The dissolving of the nucleus pulposus, the semi-gelatinous tissue of a displaced INTERVERTEBRAL DISC. It is usually achieved by the direct injection of a proteolytic enzyme, especially CHYMOPAPAIN, into the herniated disc.
Compounds containing the -SH radical.
Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
A plant genus of the family SOLANACEAE. Members contain steroidal glycosides.
A drug-metabolizing, cytochrome P-450 enzyme which catalyzes the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. EC 1.14.14.-.
A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
The composition, conformation, and properties of atoms and molecules, and their reaction and interaction processes.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
The process of cleaving a chemical compound by the addition of a molecule of water.
A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.
International organizations which provide health-related or other cooperative services.
A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.
Databases devoted to knowledge about specific genes and gene products.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
A plant genus of the family TILIACEAE. Some species in this genus are called Limetree which is nearly the same as the common name for lime (CITRUS AURANTIIFOLIA). Some people are allergic to the POLLEN.
A plant genus of the family POLYGALACEAE that contains onjisaponins, xanthones, pyrones, and benzophenones. The name is similar to other snakeroots such as ASARUM; SANICULA; ARISTOLOCHIA; AGERATINA; and others.
A dinoflagellate with a life cycle that includes numerous flagellated, amoeboid, and encysted stages. Both the flagellated and amoeboid forms produce toxins which cause open wounds on fish. Pfiesteria piscicida feeds on tissue sloughed from these wounds, as well as on bacteria and algae. It is found in Atlantic estuaries of the United States.
Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).
Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
A competitive inhibitor of nitric oxide synthetase.
The book composed of writings generally accepted by Christians as inspired by God and of divine authority. (Webster, 3d ed)
Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
A body of stories, the origins of which may be unknown or forgotten, that serve to explain practices, beliefs, institutions or natural phenomena. Mythology includes legends and folk tales. It may refer to classical mythology or to a body of modern thought and modern life. (From Webster's 1st ed)
A CALCIUM-independent subtype of nitric oxide synthase that may play a role in immune function. It is an inducible enzyme whose expression is transcriptionally regulated by a variety of CYTOKINES.

Inhibition of human and ovine acrosomal enzymes by tannic acid in vitro. (1/25)

The effect of tannic acid, a common flavonoid, on the acrosin and plasminogen activator activity and plasmin activity of human and ram spermatozoa was evaluated. Acrosin and plasminogen activator activity were determined by spectrophotometry using the chromogenic substrates N-alpha-benzoyl-DL-arginine para-nitroanilide-HCl (BAPNA) and H-D-valyl-L-leucyl-L-lysine-p-nitroanilide-2HCl (S-2251), respectively. In extracts from both human and ovine acrosomes, the activities of acrosin and plasminogen activators were susceptible to tannic acid inhibition. The inhibitory effect of tannic acid was observed at concentrations > 50 micromol l(-1) in a dose-dependent manner. In additional experiments, low concentrations of tannic acid significantly inhibited tissue-type plasminogen activator, urokinase-type plasminogen activator and plasmin activity in a concentration-dependent manner over the range 0.25-200 micromol l(-1). Tannic acid reduced the motility of ram spermatozoa at a concentration of 1000 micromol l(-1) after 2 and 3 h co-incubation with spermatozoa. The motility of human spermatozoa remained unchanged over the range 0.1-1000 micromol tannic acid l(-1) during 3 h co-incubation. These results indicate that tannic acid inhibited the activity of both acrosin and plasminogen activator and indicates a possible mechanism by which flavonoids exert their antifertility effects.  (+info)

Isolation and characterization of an alpha-macroglobulin from the gastropod mollusc Helix pomatia with tetrameric structure and preserved activity after methylamine treatment. (2/25)

A proteinase inhibitor with M(r) 697000 and 20.3% (w/w) carbohydrate was isolated from the haemolymph of the snail Helix pomatia and characterized. It was shown to have a tetrameric structure with subunits disulphide linked by two. It inhibited the activity of several types of proteinases against large substrates but not that of trypsin against N-alpha-benzoyl-DL-arginine-4-nitroanilide. This indicated a nonspecific and steric hindrance mode of inhibition. The ratio of trypsin molecules inactivated per inhibitor amounted to 1.5. This interaction led to a cleavage of the subunits into two equal fragments and to a slow to fast conformational change of the whole molecules. Experiments with 125I-labelled trypsin indicated that the proteinase had become covalently linked to one of the fragments. Heating of the inhibitor led to autolytic cleavage products but not when methylamine treated. Thiol titration after trypsin or methylamine treatment indicated the presence of one thiol ester bond per subunit. These facts are all indicative of an alpha-macroglobulin type of inhibitor. However, unlike for most of them the methylamine treatment did not induce a conformational change nor suppress its proteinase inhibitory activity. Moreover, invertebrate alpha-macroglobulins are mostly dimeric in structure but tetramers likewise do occur in Biomphalaria glabrata.  (+info)

Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-depyridyl disulphide as a reactivity probe. (3/25)

1. Fully active ficin (EC 3.4.22.3) containing 1 mol of thiol with high reactivity towards 2,2'-dipyridyl disulphide (2-Py-S-S-2-Py) at pH4.5 per mol of protein was prepared from the dried latex of Ficus glabrata by covalent chromatography on a Sepharose-glutathione-2-pyridyl disulphide gel. 2. Ficin thus prepared is a mixture of ficins I-IV and ficin G, in which ficins II and III predominate. The various ficins exhibit similar reactivity characteristics towards 2-Py-S-S-2-Py. 3. Use of 2-Py-S-S-2-Py as a reactivity probe demonstrates (a) that in ficin, as in papain (EC 3.4.22.2), the active-centre thiol and imidazole groups interact to provide a nucleophilic state at pH values of approx. 6 additional to the uncomplicated thiolate ion that predominates at pH values over 9, and (b) a structural difference between ficin and papain that leads to a much higher rate of reaction of 2-Py-S-S-2-Py with ficin than with papain at pH values 3-4. This difference is suggested to include a lack in ficin of a carboxyl group conformationally equivalent to that of aspartic acid-158 in papain. 4. The high electrophilicity of the 2-Py-S-S-2PyH+ monocation allows directly the detection of the exposure of the buried thiol group of ficin at pH values below 4.  (+info)

Evidence that Fitzgerald factor counteracts inhibition by kaolin or ellagic acid of the amidolytic properties of a plasma kallikrein. (4/25)

Fitzgerald trait, an asymptomatic disorder, is associated with abnormalities of surface-mediated plasma reactions, including coagulation via the intrinsic pathway, augmentation of the clot-promoting properties of factor VII, kaolin-mediated fibrinolysis, kinin generation, and enhancement of vascular permeability by diluted plasma (PF/Dil). These abnormalities can be corrected by Fitzgerald factor, an agent probably identical with high molecular weight kininogen found in normal, but not Fitzgerald-trait plasma. Our preparations of Fitzgerald factor possessed a second property. Amidolysis of alpha-N-benzoyl-L-proline-L-phenylalanine-L-arginine-pnitroanilide by a plasma kallikrein (activated Fletcher factor) was inhibited by kaolin or solutions of ellagic acid. Addition of preparations of Fitzgerald factor to kaolin or to solutions of ellagic acid counteracted their inhibitory properties. The action of these preparations was duplicated by solutions of cytochrome C or IgG, suggesting that these agents may inhibit the negative charges of kaolin or ellagic acid. Fitzgerald factor enhanced amidolysis of both normal and Fitzgerald-trait plasmas exposed to kaolin, effects not duplicated by cytochrome C or IgG. Whether or not the two properties of our preparations of Fitzgerald factor are related to the same agent is not yet certain. The relationship between these observations and the biologic role of Fitzgerald factor remains to be investigated.  (+info)

Evidence for independent molecular identity and functional interaction of the haemagglutinin and cysteine proteinase (gingivain) of Porphyromonas gingivalis. (5/25)

The sequence of events involved in haemagglutination and lysis of erythrocytes by washed cells, vesicles and the culture supernate of Porphyromonas gingivalis strain W83 was monitored by 51Cr release and transmission electronmicroscopy. All preparations, except capsular material and lipopolysaccharide, caused haemagglutination and, by a slow process of attachment and specific attack on the surface structures of the red blood cells, produced minute pores and eventual leakage of cellular contents. N-acetylglucosamine, N-acetylgalactosamine and several other sugars such as glucose and sucrose had no effect on haemagglutination. Antiserum raised against a cloned haemagglutinin of P. gingivalis strain 381 inhibited the activity of strain W83 cells, vesicles and supernate. The antiserum-neutralised supernate lost 70-80% of its hydrolytic activity towards alpha-N-benzoyl-L-arginine-4-nitroanilide but the residual activity behaved in a manner similar to the native supernate in that it was completely inhibited by the addition of 2,2'-dipyridyl disulphide and was fully restored upon addition of a low-Mr mercaptan. Binding of the antiserum to the haemagglutinin epitope of P. gingivalis still permitted titration of the active centre cysteinyl thiol group of the proteinase. Purified gingivain caused lysis of erythrocytes and was not neutralised by antiserum to the haemagglutinin. These results suggest that, although the haemagglutinin and gingivain are probably separate molecules, they are closely associated on the outer membrane of P. gingivalis and may be functionally related.  (+info)

Separation, purification and N-terminal sequence analysis of a novel leupeptin-sensitive serine endopeptidase present in chemically induced rat mammary tumour. (6/25)

Leupeptin is a small peptide microbially derived inhibitor of certain proteolytic enzymes. Using N-alpha-benzoyl-DL-arginine 4-nitroanilide as substrate, we found a novel leupeptin-sensitive proteolytic enzyme in N-methyl-N-nitrosourea(MNU)-induced rat mammary adenocarcinoma. This enzyme was apparently different from urokinase-type plasminogen activator or cathepsin B and was present in mammary tumour at levels at least 20 times higher than those in normal mammary tissue. This enzyme was separated and purified from crude extracts of MNU-induced mammary adenocarcinoma approx. 1900-fold with 34% yield. It was a trypsin-like serine endopeptidase and had a pH optimum at 7.0. The native enzyme had an apparent M(r) of 180,000 and exhibited four isoelectric points ranging from 4.3 to 5.0. Electrophoresis of denatured enzyme, however, yielded, with reduction, a major band with an apparent M(r) of 37,500 and a minor band with an apparent M(r) of 35,500. The N-terminal 23 residues of the major band were Ile1-Val2-Gly3-Gly4-Gln5-Glu6-Ala7-+ ++Ser8-Gly9-Asn10-Lys11-Xaa12-Pro13- Val14- Gln15-Val16-Xaa17-Leu18-Xaa19-Val20- Trp21-Leu22-Pro23. These and other properties of this enzyme suggested that it most closely resembles rat skin tryptase, followed by rat peritoneal mast-cell tryptase and then by tryptases from other species. The rat, like human and mouse, may carry multiple tryptase genes, and this mammary-tumour enzyme may be an additional form of rat tryptase within a new serine-proteinase family.  (+info)

Studies on the catalytic action of poly-alpha-amino acids. VII. Stereospecificity in the enzyme-like hydrolysis of benzoyl-L-(D)-arginine-p-nitroanilides by copoly (Cys, Glu). (7/25)

The substrate specificity in the hydrolysis of L-, DL-, and D-BAPA (benzoylarginine-p-nitro-anilide) by copoly (L-Cys, L-Glu) and copoly (D-Cys, D-Glu) was studied, and enzyme-like stereospecific hydrolyses by poly-alpha-amino acids were identified for the first time. The L-type copolymer hydrolyzed L-BAPA faster than D-BAPA and the rates (v) of BAPA hydrolyses by L-type copolymer were found to be in the order vL greater than vDL greater than vD. On the other hand, the D-type copolymer hydrolysed D-BAPA faster than L-BAPA and the rates of BAPA hydrolyses by D-type copolymer were in the order vD greater than vDL greater than vL. In all cases, the reaction followed Michaelis-Menten kinetics when the substrate concentration was corrected, and the optimum conditions of the reaction were pH 6.0 and 40 degrees. The activity appeared after a certain amount of BAPA had combined with the polymer. D- and L-substrates combine competitively with the polymer and the different rates of hydrolysis are presumably due to the different substrate configurations in relation to the conformation of the active site in the polymer. The polymer shows activity near the range of random coil conformation, where some alpha-helical conformation is still present. Only some of the cysteine residues in the copolymer are involved in the hydrolytic activity.  (+info)

Overexpression and mechanistic characterization of blastula protease 10, a metalloprotease involved in sea urchin embryogenesis and development. (8/25)

Blastula protease 10 (BP10) is a metalloenzyme involved in sea urchin embryogenesis, which has been assigned to the astacin family of zinc-dependent endopeptidases. It shows greatest homology with the mammalian tolloid-like genes and contains conserved structural motifs consistent with astacin, tolloid, and bone morphogenetic protein 1. Astacin, a crustacean digestive enzyme, has been proposed to carry out hydrolysis via a metal-centered mechanism that involves a metal-coordinated "tyrosine switch." It has not been determined if the more structurally complex members of this family involved in eukaryotic development share this mechanism. The recombinant BP10 has been overexpressed in Escherichia coli, its metalloenzyme nature has been confirmed, and its catalytic properties have been characterized through kinetic studies. BP10 shows significant hydrolysis toward gelatin both in its native zinc-containing form and copper derivative. The copper derivative of BP10 shows a remarkable 960% rate acceleration toward the hydrolysis of the synthetic substrate N-benzoyl-arginine-p-nitroanilide when compared with the zinc form. The enzyme also shows calcium-dependent activation. These are the first thorough mechanistic studies reported on BP10 as a representative of the more structurally complex members of astacin-type enzymes in deuterostomes, which can add supporting data to corroborate the metal-centered mechanism proposed for astacin and the role of the coordinated Tyr. We have demonstrated the first mechanistic study of a tolloid-related metalloenzyme involved in sea urchin embryogenesis.  (+info)

Bapa Gereja adalah sebutan bagi para teolog dan filsuf yang berpengaruh dan hidup di era awal Gereja Kristen.[1] Secara khusus, sebutan ini diberikan bagi mereka yang hidup pada lima abad pertama dalam sejarah Kekristenan, meskipun pada praktiknya digunakan untuk menyebut para tokoh gereja sampai pada abad ke-8 atau bahkan lebih dari itu.[1] Hal ini terlihat jelas pada masa gereja-gereja awal.[1] Sebutan ini juga digunakan bagi para pujangga dan pengajar di gereja.[1] Namun, bukan berarti bahwa tokoh yang bersangkutan harus pula seorang santo.[1] Umumnya istilah ini tidak mencakup para penulis kitab-kitab Perjanjian Baru, sekalipun pada masa awal Gereja beberapa karya tulis dari para Bapa Gereja dipandang kanonikal.[2] Bapa-bapa gereja memiliki pemikirannya masing-masing tentang kekristenan.[2] Hal inilah membuat mereka terkenal di kalangan umat Kristen.[2] Setiap Bapa Gereja dibagi berdasarkan bahasa dan tempat asalnya.[2] Bapa Gereja yang menulis dalam bahasa Latin contohnya disebut Bapa ...
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2,4-dinitrophenyl-valyl-2-aminoisobutyryl-glycyl-leucyl-4-nitroanilide: RN refers to (L,L)-isomer; structure given in first source
The story of the Fitzgerald shipping clan begins in the early 19th century, when William and Julianna Fitzgerald left Ireland. Edmunds great-grandparents were immigrants from Ireland and settled first in China Township, St. Clair County, in 1837, on a farm near Marine City, Michigan, local historian Dick Wicklund wrote in a 2006 edition of The Lightship, the newsletter of the Lake Huron Lore Marine Society.. Six of the Fitzgerald boys eventually became captains on the Great Lakes later in the 19th century, including the oldest, Edmond (spelled with an o) and the youngest, John, who relocated to Milwaukee. Johns own son William eventually took control of a family shipyard, which had been established in Milwaukee. Sadly, William Fitzgerald died when his youngest son, Edmund, (with a u) was just six years old.. A fellow Irish-American veteran of the sea, Captain Dennis Sullivan, sought to honor the memory of Edmunds father by naming a ship after him, christening the W.E. Fitzgerald in ...
Ella Jane Fitzgerald was born in Newport News, Va., on April 25, 1917. Fitzgerald got her start as a singer in 1934 when her name was pulled in a weekly drawing at the Apollo Theatre and she won the opportunity to compete in Amateur Night. Fitzgerald went to the theater that night planning to dance, but made the last minute decision to sing. She quickly quieted the audience, and by the songs end they were demanding an encore. Offstage, and away from people, she knew well, Fitzgerald was shy and reserved. She was self-conscious about her appearance, and for a while even doubted the extent of her abilities. Onstage, however, she was surprised to find she had no fear. She felt at home in the spotlight.. In mid-1936, Fitzgerald made her first recording, it was with the great band leader, Chick Webb. Love and Kisses was released under the Decca label, with moderate success. By this time she was performing at the prestigious Harlems Savoy Ballroom, often referred to as The Worlds Most Famous ...
Setelah selesai membeli segala keperluan dapur untuk bekalan sepanjang minggu, kedai terakhir Amie singgah sudah tentulah kedai kek. Alhamdulillah, dapat sebiji Cappuccino Cake yang comel. Oleh kerana Encik Suami akan pulang ke rumah lewat petang nanti, sempatlah Amie memikirkan hidangan untuk meraikan hari ulang tahunnya merangkap hari bapa pada hari ini. Terkenang tahun-tahun sebelum ini, memang kami menjadi tuan rumah untuk sambutan hari bapa pada setiap tahun. Ayahanda mentua, abang ipar duai dan biras semua berkumpul di rumah kami, tetapi tahun ini .... mungkin setelah pemergian ayahanda mentua, suasana agak lengang dan sepi! Masing-masing dengan cerita keluarga sendiri. Apa pun, insya-Allah sambutan peringatan untuk kaum bapa ini kami sambut seadanya! ...
FitzGerald, JM, Sadatsafavi M. Triple therapy in a single inhaler: a new option for uncontrolled asthma. Lancet. 2019 Sep 30. pii: S0140-6736(19)32216.. Halpin DMG, Meltzer EO, Pisternick-Ruf W, Moroni-Zentgraf P, Engel M, Zaremba-Pechmann L, Casale T, FitzGerald JM. Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV1. Respir Res. 2019 Jul 18;20(1):159. doi: 10.1186/s12931-019-1119-6.. Reddel HK, FitzGerald JM, Bateman ED, Bacharier LB, Becker A, Brusselle G, Buhl R, Cruz AA, Fleming L, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Pedersen SE, Sheikh A, Yorgancioglu A, Boulet LP. GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents. Eur Respir J. 2019 Jun 27;53(6). pii: 1901046. doi: 10.1183/13993003.01046-2019.. Castro M, Corren J, Pavord ID, Maspero J, Wenzel S, Rabe KF, Busse WW, Ford L, Sher L, FitzGerald JM, Katelaris C, Tohda Y, Zhang B, ...
About Us Located in a small town just inside the Kentucky state line is home of Fitzgerald Industries At Fitzgerald Industries our team of experienced metal fabricators welders and painters work hard to build some of the best products hands down There is no doubt that Fitzgerald Industries is built on hard work and a love for fine metal craftsmanship FITZGERALD INDUSTRIES Our products Get Price ...
To what extent and in what ways is Fitzgerald purely critical of Gatsby?. Due to Fitzgeralds seeming disregard for Daisy in the novel, I believe that he is critical of Gatsbys dream to be with her. However, I believe the other aspects of his presentation linking to dreams in a wider context prevent this view from seeming as if he is purely critical of it - the way that he suggests dreams are important to human nature and separate Gatsby from the crowd imply that Fitzgerald finds dreaming admirable, to an extent. For him to be purely critical I believe that he would have to feel purely critical of dreaming in general, which I believe not to be the case. Therefore, I believe the conclusion that Fitzgerald is critical to an extent is far more feasible and takes into account the more positive aspects of dreaming that he seems to incorporate and believe in.. ...
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Humble Dentist, Dr Sean E. Fitzgerald, DDS., PA. is a dental professional dedicated to General, Family & Cosmetic Dentistry with services including Dental Exams, Dental Makeovers, Teeth Whitening, Veneers, Crowns, X-rays, Fluoride, Cleanings, & more. Please come and visit Humble, TX dentist Dr Sean E. Fitzgerald, DDS. PA.
N. Bhaskar Ms. Budacki American Literature 19 December 2013 Author Report on F. Scott Fitzgerald F. Scott Fitzgerald is one of the greatest American authors....
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Jennifer Fitzgerald leads a full cast in this compelling work of speculative fiction about solving the climate crisis around the world. Fitzgerald doe
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Titania and the Changeling; Scene from A Midsummer Nights Dream - John Anster Fitzgerald - WikiGallery.org, the largest gallery in the world: wikigallery - the largest virtaul gallery in the world with more than 150,000 on display. Always open and always free!
In 1968, Richard Nixon had a secret plan to end the war in Vietnam, and he was not going to lay out specifics. It worked. Many voters took Nixon on faith, figuring he had to be better than the Democrats who got us mired there. - Thomas Fitzgerald, Philadelphia Inquirer
Shop Fast Deliver Mens Suits - Fitzgerald Denim Jacket available online at discount prices from Finephotography.co.nz. Fabric: 100% WoolBlock: Drop 7Range: Classicsl Make returns in store or by mail.Free shipping.
GLENDALE, Ariz. (AP) - Larry Fitzgerald took a moment Tuesday to talk about the retirement of his good friend and former teammate Anquan Boldin. Its bittersweet,
48 Collins Square,Benburb Street,Dublin 7,D07 TD79, 2 Bed, asking price €385,000, brought to market by Sherry FitzGerald Phibsborough, Residential - 4527427 (rated C3)
Sarver dentist, Kimberly Fitzgerald, DDS is a local, trusted dental practice offering general and cosmetic dentistry, teeth whitening, implants, veneers & other dental care. Call today to make an appointment!
Fitzgerald (No. 2.) of Kildare, Dukes of Leinster, family history, from Irish Pedigrees; or the Origin and Stem of the Irish Nation, by John OHart
by emptywheel There has been a lot of speculation this week about whether, and when, Karl Rove will be indicted. While everyone has been distracted with that excitement, Patrick Fitzgerald has laid a few more of his cards on the...
by emptywheel There has been a lot of speculation this week about whether, and when, Karl Rove will be indicted. While everyone has been distracted with that excitement, Patrick Fitzgerald has laid a few more of his cards on the...
Dr. Carlton Lue, MD, BS, MBBS, rated 5/5 by patients. 2 reviews, Phone number & practice locations, Internist in Fitzgerald, GA.
Cho, K., Tanaka, T., Cook, R.R., Kisiel, W., Fujikawa, K., Kurachi, K. and Powers, J.C. (1984). „Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates. Biochemistry. 23: 644-650. PMID 6370301 ...
Chan, K.H., Singh, H.P., Aherne, T., Carabine, U., Gilliland, H., Johnston, J.R., Lowry, K.G., McGuigan, J., Cosgrove, J., Veerasingham, D., McCarthy, J., Hurley, J., Wood, A.E., Gilliland, R., McGuigan, J.A., McManus, K.G., Wilkinson, P., Johnston, L.C., MacMahon, J., Wilson, D., Austin, C., Anikin, V., McManus, K., McGuigan, J., McManus, K., Anikin, V., Gibbons, J.R.P., McGuigan, J., Sharkey, R., Long, M., Maree, A., ONeill, S., Maguire, C.P., Hayes, J.P., Masterson, J., Fitzgerald, M.X., Hayes, M., Maguire, C.P., Hayes, J.P., Masterson, J., Fitzgerald, M.X., Quigley, C., Mofidi, A., Mofidi, R., Fitzgerald, M.X., ONeill, M., Watson, J.B.G., OHalloran, E.T., Shortt, C., Taylor, M., Holland, C., OLorcain, P., Taylor, M., Holland, C., OLorcain, P., Pathmakanthan, S., Sreenan, S., Power, C.K., Poulter, L.W., Burke, C.M., Reilly, D., Pathmakanthan, S., Sreenan, S., Doyle, S., Burke, C.M., Sreenan, S., Power, C., Pathmakanthan, S., Goggin, A., Burke, C.M., Poulter, L.W., Sreenan, S., Doyle, S., ...
An approach was proposed to the selection of promising titrants using computer databases. The approach takes into account the absolute and relative stabilities
Good Samaritan Hospitals Samaritan of the Month for February was Karen Fitzgerald, RN. A nurse with Good Sam since 2002, Ms. Fitzgerald has worked alongside staff in the hospitals Medical Intensive Care Unit joining the Nursing Education Team in 2005. As a Critical Care Educator she is a valuable employee who has contributed endless hours to many areas of the hospital ...
NEWTON, Wis. - Just like the crops they grow, so has the appreciation and respect the Fitzgerald sisters have for one another.. Now grown and married, Stacy Klotz, 31; Kelly Goehring, 42; and Julie Maurer, 43,work together in partnership with their parents - Jim and Sandie Fitzgerald - to run Soaring Eagle Dairy in Newton.. Ever since we were little kids, we all pitched in, Klotz said. Whether it was milking cows or picking up another chore, the sisters were kept busy on the farm, which has changed over the years. Their paternal grandfather, John, who began by milking eight cows by hand when he was 18, later started the farm with his son, Jim. The farm is now home to 1,150 cows.. As they graduated from high school, Goehring, Klotz, and earlier their father, took the 16-week Farm and Industry Short Course program at the University of Wisconsin-Madison following high school. Goehring was the first daughter to join the family farm as a partner in 1997. Klotz and Maurer followed in 2005.. Ive ...
I was diagnosed in 2012 - I went to the doctor when my vision was degrading rapidly; you dont tend to wait too long to go to a doctor when something goes wrong with your eyes.. I was referred to an ophthalmologist who initially suspected HIV or Bechet so ran some blood tests. The next day, I got a call and was asked if I could go to Barts Hospital where theyd be expecting me for some tests. I happened to be working just a few minutes away from there, and they said I should go right away because the blood test showed very high white counts and many other abnormalities. Naively I thought this was all routine stuff and told my wife thered be no need to come and join me at the hospital.. When I arrived and was in the waiting room, I couldnt help but notice I was clearly in a haematology department - it was then that I cottoned on that cancer was on the cards. Sure enough, the consultant spoke to me and said that they were virtually certain I had chronic myeloid leukaemia (CML) and theyd take a ...
Cm tidak mahu berlaku kejadian beberapa tahun yang lepas yang diceritakan oleh anak CM, yg kawannya menangis kerana guru seninya memaksa membuat kad untuk hari bapa, dan akhirnya barulah di ketahu yang sebabnya hanya bapanya sudah meninggal dunia ...
S. Gullapalli, K. Czajkowski, C. Kesselman, and S. Fitzgerald, The Grid Notification Framework, Global Grid Forum, Junho de, 2001. ...
Underpinning this entertaining work- a romp through genes of the past ranging from vampires to John Fitzgerald Kennedys - is a serious study of how genetic disorders may have changed world
Directed by James Ivory. With Susan Blakely, Margaret Brewster, Thayer David, Neil Fitzgerald. An allegory about humankind progresses from a savage state to a civilized form, that is only a cover for its innate barbarism.
Matt Fitzgerald gives insight on the new training techniques for teaching running technique, including Chi Running and Pose Running.
Brisbane, Queensland (PRWEB) July 25, 2012 -- Luke Fitzgerald, Director of Sanofi Consumer Healthcare, the owners of Natures Own said the partnership
F. Scott Fitzgerald was a very good writer, but one of his most famous lines is about as wrong as it can be. Its actually a cliché to point out the com… Read More ...
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Sunn pest (Eurygaster integriceps Put.) is one of the major pests of wheat in Iran. Identification of resistantcultivars is an effective integrated pest management (IPM) strategy. To identify the genetic response of wheat and triticale to Sunn pest, and determine the relationship between resistance and morpho physiological traits, eight bread wheat breeding lines/cultivars, four durum wheat lines, three triticale lines and five synthetic wheat lines were evaluated for resistance to Sunn pest. The response of these genotypes to Sunn pest was evaluated in the field under artificial infestation in cages using a randomized complete block design with three replications. At heading, eight adult insects were released into each cage (30×40×120 cm) and 30 nymphs were released at the grain-filling stage. Spike damage (%) and grain damage (%) were recorded. An analysis of variance revealed significant differences among the genotypes for spike injuries caused by adult insects. Cultivar Falat (1.8% spike damage)
UMETSUBO, Otavio Shoiti; GAIA, Bruno Felipe; COSTA, Felipe Ferreira and CAVALCANTI, Marcelo Gusmão Paraiso. Detection of simulated incipient furcation involvement by CBCT: an in vitro study using pig mandibles. Braz. oral res. [online]. 2012, vol.26, n.4, pp.341-347. ISSN 1807-3107. http://dx.doi.org/10.1590/S1806-83242012000400010.. The aim of the present study was to test the reproducibility, sensitivity, and specificity of cone-beam computed tomography (CBCT) in detecting incipient furcation involvement. Fifteen macerated pig mandibles, with intact second molar teeth and preserved adjacent cortical areas, were used. Simulated lesions were created in the furcation region of these teeth by applying 70% perchloric acid in up to four possible buccal/lingual sites in the right/left sides of each mandible. The mandibles were then submitted to a CBCT scan. Two blinded and calibrated experienced oral and maxillofacial radiologists interpreted the exams. Furcation involvement was also assessed in the ...
0038] Specific crystalline resins include poly(ethylene-adipate), poly(propylene-adipate), poly(butylene-adipate), poly(pentylene-adipate), poly(hexylene-adipate), poly(octylene-adipate), poly(ethylene-succinate), poly(propylene-succinate), poly(butylene-succinate), poly(pentylene-succinate), poly(hexylene-succinate), poly(octylene-succinate), poly(ethylene-sebacate), poly(propylene-sebacate), poly(butylene-sebacate), poly(pentylene-sebacate), poly(hexylene-sebacate), poly(octylene-sebacate), poly(decylene-sebacate), poly(decylene-decanoate), poly(ethylene-decanoate), poly(ethylene dodecanoate), poly(nonylene-sebacate), poly(nonylene-decanoate), copoly(ethylene-fumarate)-copoly(ethylene-sebacate), copoly(ethylene-fumarate)-copoly(ethylene-decanoate), copoly(ethylene-fumarate)-copoly(ethylene-dodecanoate), copoly(2,2-dimethylpropane-1,3-diol-decanoate)-copoly(ethylene-adipate), alkali copoly(5-sulfoisophthaloyl)-copoly(propylene-adipate), alkali ...
Summary The sequence of events involved in haemagglutination and lysis of erythrocytes by washed cells, vesicles and the culture supernate of Porphyromonas gingivalis strain W83 was monitored by 51Cr release and transmission electronmicroscopy. All preparations, except capsular material and lipopolysaccharide, caused haemagglutination and, by a slow process of attachment and specific attack on the surface structures of the red blood cells, produced minute pores and eventual leakage of cellular contents. N-acetylglucosamine, N-acetylgalactosamine and several other sugars such as glucose and sucrose had no effect on haemagglutination. Antiserum raised against a cloned haemagglutinin of P. gingivalis strain 381 inhibited the activity of strain W83 cells, vesicles and supernate. The antiserum-neutralised supernate lost 70-80% of its hydrolytic activity towards α-N-benzoyl-L-arginine-4-nitroanilide but the residual activity behaved in a manner similar to the native supernate in that it was completely
A microreactor by immobilized trypsin on the activated glycidyl methacrylate-modified cellulose membrane packed column was constructed, Immobilized trypsin mirrored the properties of the free enzyme and showed high stability. A novel method to characterize the activity and reaction kinetics of the immobilized enzyme has been developed based on the frontal analysis of enzymatic reaction products, which was performed by the on-line monitoring of the absorption at 410 nm of p-nitroaniline from the hydrolysis of N-alpha -benzoyl-DL-arginine-p-nitroanilide (BAPNA). The hydrolytic activity of the immobilized enzyme was 55.6% of free trypsin. The apparent Michaelis-Menten kinetics constant (K-m) and V-max values measured by the frontal analysis method were, respectively, 0.12 mM and 0.079 mM min(-1) mg enzyme(-1). The former is very close to that observed by the static and off-line detection methods, but the latter is about 15% higher than that of the static method. Inhibition of the immobilized ...
Viewray Inc (NASDAQ:VRAY) - Research analysts at Cantor Fitzgerald dropped their FY2017 earnings estimates for shares of Viewray in a research report issued on Sunday. Cantor Fitzgerald analyst C. Bijou now anticipates that the company will post earnings of ($1.08) per share for the year, down from their previous estimate of ($1.03). Cantor Fitzgerald currently […]
Aurinia Pharmaceuticals Inc (TSE:AUP) (NASDAQ:AUPH) - Stock analysts at Cantor Fitzgerald reduced their FY2017 earnings estimates for shares of Aurinia Pharmaceuticals in a research note issued on Monday. Cantor Fitzgerald analyst E. Piros now expects that the company will earn ($1.35) per share for the year, down from their prior estimate of ($1.27). Cantor Fitzgerald […]
Heliothis virescens is a major lepidopteran pest of cotton in the United States and the target insect of Bacillus thuringeinsis (Bt) transgenic cotton. We conducted an analysis of gut proteases from Bt susceptible and resistant H.virescens strains, including the susceptible strain, YDK, and three resistant strains, YHD2-B, CXC, and KCBhyb. Casein zymogram analysis of YDK and YHD2-B gut extracts did not reveal significant differences. However, two unique bands of caseinolytic activity were observed in CXC and KCBhyb. Kinetic microplate assays with a trypsin substrate demonstrated that proteinases in YDK gut extract had more alkaline pH optima compared to YHD2-B, CXC and KCBhyb. In assays with a chymotrypsin substrate, enzymes in YDK extracts had lower alkaline pH optima in contrast to those in YHD2-B gut extract. Enzymes from KCBhyb gut extracts had the highest activity of all strains in alkaline buffers, particularly at pH 10.6, similar to the physiological pH of the lepidopteran midgut. ...
The maize beta-D-glucosidase Zm-p60.1 releases active cytokinins from their storage/transport forms, and its over-expression in tobacco disrupts zeatin metabolism. The role of the active-site microenvironment in fine-tuning Zm-p60.1 substrate specificity has been explored, particularly in the W373K mutant, using site-directed random mutagenesis to investigate the influence of amino acid changes around the 373 position. Two triple (P372T/W373K/M376L and P372S/W373K/M376L) and three double mutants (P372T/W373K, P372S/W373K and W373K/M376L) were prepared. Their catalytic parameters with two artificial substrates show tight interdependence between substrate catalysis and protein structure. P372T/W373K/M376L exhibited the most significant effect on natural substrate specificity: the ratio of hydrolysis of cis-zeatin-O-beta-D-glucopyranoside versus the trans-zeatin-O-beta-D-glucopyranoside shifted from 1.3 in wild-type to 9.4 in favor of the cis- isomer. The P372T and M376L mutations in ...
Patrick J. Fitzgerald is confirmed as US Attorney for the Northern District of Illinois, centering in Chicago. Senator Peter Fitzgerald (R-IL-no relation to Patrick Fitzgerald) nominated Fitzgerald for the position because he felt Fitzgerald, a native New Yorker and veteran prosecutor with no ties to Chicago, would be less likely to become corrupted by what he thought to be the Chicago Democrat machine. Fitzgerald had come highly recommended by, among others, Louis Freeh, then the director of the FBI. White House political chief Karl Rove later says that he did not oppose Fitzgeralds nomination, though he was somewhat disturbed by Senator Fitzgeralds insistence on the nomination. Rove will recall: Senator Fitzgeralds attitude was: Im not going to submit multiple names. I will take only one name, and this is all that is going to be acceptable. And we asked him to submit multiple names, and we also asked him to think about people from within the districts. Our predilection was to have ...
Fitzgeralds first major stage role came in 1992 when she appeared opposite Peter OToole in Our Song at the Apollo Theatre. She has alternated between stage and screen for almost two decades, with frequent theatre roles. In 1995, she starred as Ophelia opposite Ralph Fiennes in Hamlet at Londons Almeida Theatre, which led to her American stage debut. The production transferred across the Atlantic and played more than 90 performances on Broadway at the Belasco Theatre. Since then she has played Antigone in a national UK tour and Blanche Du Bois in Tennessee Williamss A Streetcar Named Desire at the Bristol Old Vic[7] and appeared with Gillian Anderson in A Dolls House at the Donmar Warehouse. Fitzgerald has also appeared in Molières The Misanthrope in 2009 with Keira Knightly and Damian Lewis at the Comedy Theatre (now the Pinter). She appeared alongside Jo Stone-Fewings in The Winters Tale at the RSC in 2013 and appeared in Gaslight at the Royal and Derngate Theatre in 2015. Fitzgerald is ...
Your privacy is a very important priority at Fitzgerald Health Education Associates, Inc. While doing business with Fitzgerald, we gather nonpublic personal information from you such as name, mailing address, phone, e-mail and payment information. Appropriate use of the information is at the heart of our ability to provide you with exceptional customer service whenever and however you contact us. We want you to understand how we manage your information so that you can have confidence that your information is handled discretely.. Communications with our customers. Individuals and organizations in Fitzgeralds customer file are initially set to receive periodic mail and email from the company including catalogs, newsletters, and announcements about company products, events all of which are pertinent to the primary care role. Each such communication gives the receiving individual the opportunity to opt out of all such future communication with the exception of notices directly concerned with a ...
With the writers we read again and again, our interpretation of their stories and legacies tends to change over time. Francis Scott Key Fitzgerald is buried at Saint Marys Catholic Church in Rockville, Maryland, and although he was not born, did not die, and did not even spend any significant time in Rockville, it seems perversely fitting: Fitzgerald moved…
Mercy Fitzgerald Hospital in Darby, PA - Get directions, phone number, research physicians, and compare hospital ratings for Mercy Fitzgerald Hospital on Healthgrades.
Management of teeth with furcation involvement (FI) is challenging for the clinician. The greater the grade of FI, the more difficult it becomes to treat. Also, the grade of FI affects the prognosis...
This study explores the relationship between defined antigens of the C3 molecule and those surface structures that are involved in interaction with factors I and H. Methylamine treatment at pH 11 followed by neutralization converts C3 into a modified state in which the molecule is optimally susceptible to cleavage by factor I in the presence of factor H. The modified C3 is characterized by an antigenic profile with expression of antigens of the C3(N), C3(S), and C3(D) subsets. These antigenic properties closely mirror those of physiologically bound C3b, suggesting that modification of antigenic expression upon denaturation of C3 reflects a regulatory mechanism for I and H function. Immunochemical studies of the alkaline-denatured C3 suggested that factor H interacts with surfaces of C3 that are situated within the C3c fragment and that are defined by C3(SN) antigens, while factor I predominantly interacts with C3(SN) antigens associated with the C3d fragment and with C3(D) antigens hidden in ...
Dugaan demi dugaan yang menimpa diri Nurul membuatkan diri Nurul lemah jatuh tak berdaya.Setiap kepahitan Nurul telan sendiri semata-mata tidak ingin menyusahkan orang lain.Nurul manusia yang kadang-kala lemah seperti ranting.Walaupun Nurul tersenyum tapi semua tu tak bermakna Nurul bahagia dengan apa yang Nurul dapat.Anak mana yang tak terluka bila lihat ibu bapa dia dihina sesuka hati.Sejahat mana pun mereka,mereka tetap ibu bapa kita.Sanggup ke kita tengok ibu bapa kita kena hina?Nurul tahu semua tu hanya dalam alam facebook tapi tak bermakna kita boleh hina orang sesuka hati ...
. . . Last year the Fullerton Rag insisted that Council member (now Mayor Pro Tem) Jennifer Fitzgerald should recuse herself from voting on a representative to replace her on […]
PATRICK W. FITZGERALD, PH.D, ED.D., J.D. (405) and cell Professional Experience Visiting Scholar at Vanderbilt University, Visiting Scholar at the University
F. Scott Fitzgerald. The 1920s, also known as the Jazz Age, were wild times, and Francis Scott Fitzgerald was its king. Although he led a wild and luxurious lifestyle, Fitzgerald was known more for his prominent works of literature, which have gained a permanent place among the American classics. This CD set contains two short stories from his book Tales of the Jazz Age, which reflect the era and lifestyle of which Fitzgerald was accustomed.. ...
Edmund Fitzgerald Porter is a American Porter style beer brewed by Great Lakes Brewing Co. in Cleveland, OH. 4.24 average with 6531 ratings, reviews and opinions.
Fitzgerald online testing provides detailed rationales for every question and analysis of knowledge gaps provides feedback to help focus your study ...
Dr. Kathleen Fitzgerald, MD, rated 4.2/5 by patients. 11 reviews, Phone number & practice locations, Obstetrician & Gynecologist in Providence, RI.
Injectable trainer and expert injector Rebecca Fitzgerald MD discusses the benefits of BOTOX for reducing jaw muscle size - Visit us in LA for a consult
Get instant advice on your decision to start Larry Fitzgerald or Alshon Jeffery for Week 11. We offer recommendations from over 100 fantasy football experts along with player statistics, the latest news and matchup information.
Periodontal - Gum Disease Treatment Fitzgerald. Avoid the development of gum disease & other oral health complications, schedule your appointment with us now!
Sarver dentist, Kimberly Fitzgerald, DDS is a local, trusted dental practice offering general and cosmetic dentistry, teeth whitening, implants, veneers & other dental care. Call today to make an appointment!
Make ANY Day Festive with a Stylish Floral Arrangement Designed and Delivered by CLASSIC DESIGN FLORIST. We Can Surprise Someone Special for You! Feel Free to Call Us or Order Flowers Online 24/7. Order White Bubble Bowl Vase of Flowers from CLASSIC DESIGN FLORIST - Fitzgerald, GA Florist & Flower Shop.
Edmund Fitzgerald Porter is a American Porter style beer brewed by Great Lakes Brewing Co. in Cleveland, OH. 4.24 average with 6544 ratings, reviews and opinions.
Visit Healthgrades for information on Dr. Richard Fitzgerald, DDS Find Phone & Address information, medical practice history, affiliated hospitals and more.
Fabulous: Larry Fitzgerald, who deserves a better quarterback by now. Fitzgerald caught only seven of the 13 passes thrown to him, but oh, the catches he made. He finished with 146 yards and two touchdowns on the day, and he was inches away from producing a third with an incredible diving catch. Of course, this isnt exactly something new with Fitzgerald and the Eagles. In four games against Philadelphia, Fitzgerald now has 26 catches for 456 yards and eight touchdowns. Eight!. Flop: Michael Vick. Vick deserves some toughness points for playing through two broken ribs for most of the game, but he also deserves some toughness demerits for that very same reason. Vick simply wasnt accurate as a passer, completing just 47 percent of his passes and throwing two interceptions (although one was something close to a Hail Mary) while notably missing a wide-open Brent Celek for what would have been an easy touchdown. His passer rating of 32.5 was the lowest of Vicks Eagles career, and he had 25 starts ...
Introduction. How is the Story told in Chapter One? Through chapter one Fitzgerald uses a variation in technique to tell the story, he uses the character of Nick Carraway to begin the narration and through chapter one we are introduced to a handful of other characters including Daisy, Tom, Jordan and Gatsby. The use of narratorial voice is exceptionally important in Great Gatsby as Fitzgerald has created the character of Nick not only to narrate and relay the story but in tern participate and therefore the novel we hear can be argued as a personal and bias account from the character of Nicks perspective. Each character is described through the narrators voice and therefore the perceptions and thoughts of each character are effected by Nick and his views. ...read more. Middle. Fitzgerald has created the character of Nick as a participant of the story, although he is more of a spectator. The brief beginning summary is then followed by And so it happened that on a warm windy evening.. which can ...
bagi neeza kan, masalah ni bermula di rumah. Kalau ibu bapa jenis yang suka sorok2, anak2 pun jadi macam tu. Depan baik, belakang Allah saja yang tahu... jadi, untuk neeza dan yang lain-lain sebagai ibu bapa, kita kena tunjuk tingkah laku yang baik depan dan belakang. Barulah anak2 ikut... ...
Jodoh yang terbaik adalah pilihan jodoh yang direstui ibu dan bapa. Sebuah hubungan akan berjaya dengan restu ibu bapa. Ambil masa yang lama untuk kenal pasangan kita, perkenalan selama 2 3 bulan belum cukup untuk kita mengenal hati budi oarang tersebut. Jangan kalut-kalut, kalau ada jodoh tak ke mana jua ...
Memahami anak. Adakah anda memahami perkara yang dilakukan oleh anak? Mengapa anak kecil memandang anda dan sejurus selepas itu memukul abangnya atau melontarkan sesuatu ke atas lantai? Tidakkah dia tahu itu sesuatu yang salah?. Dia mungkin tahu tetapi tidak bermakna apa yang dilakukan itu jahat. Sebaliknya, kebanyakan kanak-kanak berada dalam kedudukan menerokai had mereka. Inilah satu proses normal dan merupakan sebahagian daripada perkembangan semula jadi. Jika anda berusaha memahami rasional anak, boleh jadi kemarahan dan reaksi anda tidaklah seteruk yang disangkakan.. Sebahagian besar ibu bapa telah mengukuhkan perilaku buruk anak tanpa disedari. Keadaan ini boleh berlaku apabila anak disalurkan dengan pelbagai perhatian negatif dan tidak konsisten. Sekiranya anda masih tidak dapat memahami mengapa anak bertindak sedemikian, maka ini mungkin bermakna teknik mendisiplinkan anak anda itu tidak berkesan.. Pemakanan sihat. Dewasa ini kebanyakan ibu bapa dilihat cenderung memanjakan anak. Malah, ...
Ok, so HOW is Fitzgerald such an icon of American literature? I understand how the bob was such a symbol of the newly liberated woman, truly I do; thats why I watched this. But theres none of that in this piece. Women are groomed, domestic, house pets: its hideous! The story is taken from letters Fitzgerald wrote to a young, female relative, telling her how to be more attractive to men. Sad. If Id met a man from an ivy league school, Id be brimming with questions about curriculum and all! I get that these are self conscious and small minded youngsters; does that deserve a story? Does it deserve a National Endowment for the Humanities grant to make into such a lackluster and poorly produced piece for public broadcasting? First thing, the tape hiss is horrible, and I have tinnitus, so Im accustomed to a hiss. The sound engineer should be badly punished for the terrible mixing of interior scenes. I blame this, in part, for shooting inside real houses: floor clunks, reverb off walls, etc. But ...
Farmer, D. L., Emery, H., Malloy, M., Ablin, A., Wara, W. M., Holliday, M. A., Grumbach, M., Ammann, A., Mathias, R., Kogan, B., Elder, M. E., Desantes, K., Baekkeskov, S., Styles, L., Shannon, K., Flori, H., Erlich, H., Lubin, B. H., Folkman, S., Gregory, G., Siegel, B. S., Reed, W., Albanese, C., Treadwell, M., Von Scheven, E., Teitel, D., Rosenthal, P., Harmatz, P., Baskin, L., Cowan, M., Rosenthal, S., Miaskowski, C., Miller, W., Clyman, R., Dorenbaum, A., Boyce, W. T., Fitzgerald, P., Moscicki, A. N., Harrison, M., Packman, S., Bolinger, A. N. N., Barkovich, A. J., Zlotnick, C., Kaplan, S., Dorenbaum, A., Singer, S., Franck, L., Styles, L., Boyce, W. T., Fitzgerald, P., Morris, C., Moscicki, A. N., Fineman, J., Lubin, B. H., Mathias, R., Elder, M. E., Desantes, K., Phibbs, R., Shannon, K., Flori, H., Prados, M., Butensky, E., Newman, T., Boushey, H., Hawgood, S., Miller, S., Singer, T., Portale, A., Slavotinek, A. M., Vichinsky, E., Treadwell, M., Banerjee, A., Von Scheven, E., Packman, S., ...
The story continues: Two days after recording Strayhorns song Something to Live For, on March 23, 1939, Duke Ellington and His Orchestra departed for a tour of Europe, returning to New York on May 10. While they were gone, Strayhorn, in residence at the Ellington penthouse, began studying Ellingtons scores. Duke later recalled the result of that: …he looked at my things and decided, I suppose, that it all looked very simple, so when I came back he said, Ive been looking at your things and I think I could do some of that. (5) In reality, Strayhorn then began to create more of his own unique compositions and arrangements. To the extent they sounded Ellingtonian was because Strayhorn, at first, adopted somewhat Dukes approach of writing for individual musicians in the band, and cross-sectional voicing of instruments. And of course any music played by the Ellington band sounded Ellingtonian because of the strong instrumental identities of so many of the bands members. Soon however, ...
Taught by national and international speaker, and imaging expert Dr. Theresa Campo, this course will help you learn how to evaluate extremity injuries, order imaging, and interpret X-rays. Common adult and pediatric orthopedic injuries are discussed.. Based on the mechanism of injury, pain, and clinical findings, you will learn to:. ...
AFL presented the Naruse Scholarship Award last month to Sean Fitzgerald, son of Joe Fitzgerald, Engineering Software Manager for AFLs Test and Inspection Division.
Title: A Dangerous CollaborationAuthor: Deanna RaybournSeries: Veronica Speedwell, #4Pages: 336Publisher: BerkleyDate: March 12, 2019Summary:Vic...
Hospital Moving Services in D.C. | Alexandria, VA | Fitzgerald: Fitzgerald Commercial Movers is the leading provider of hospital moving services in D.C., Alexandria, VA, & surrounding areas.
View Jacquie Fitzgeralds professional public profile. Doximity is the leading professional network exclusively for Physicians. Claim your profile.
Tim Russerts testimony, as elicited by the defense, painted a picture of a pundit with a puzzling problem. Arianna Huffington has a great collection of links and a quick summary of Russerts baffling testimony and Jane Hamsher offered some helpful...
By 1912, Desmond FitzGerald (b. 1846 - d. 1926), Brookline, MA; 1927, sold by the estate of Desmond FitzGerald to the MFA for $100. (Accession Date: May 5, 1927) ...
There is a certain kind of catharsis that comes from the collapse of a structure, perhaps within the learning that we may continue to live without it. So while I have a tendency to mark all my intentions, I also understand to have the space to chew and uproot is ...
The ensuing week was the toughest in his life not even a moment to make a pass at Katherine Hodge. Gradually with many creaks, his battered hulk got in motion. Benzedrine and great drafts of coffee woke him in the morning, whiskey anesthetized him at night. Into his feet crept an old neuritis and as his nerves began to crackle he developed a hatred against René Wilcox, which served him as a sort of ersatz fuel. He was going to finish the script by himself and hand it to Berners with the statement that Wilcox had not contributed a single line. But it was too much Pat was too far gone. He blew up when he was half through and went on a twenty-four-hour bat and next morning arrived back at the studio to find a message that Mr. Berners wanted to see the script at four. Pat was in a sick and confused state when his door opened and René Wilcox came in with a typescript in one hand, and a copy of Berners note in the other. ...
... benzoylarginine-2-naphthylamide MeSH D12.125.068.050.100 - benzoylarginine nitroanilide MeSH D12.125.068.050.400 - homoarginine ... benzoylarginine-2-naphthylamide MeSH D12.125.095.104.100 - benzoylarginine nitroanilide MeSH D12.125.095.104.400 - homoarginine ...
D-benzoylarginine-4-nitroanilide amidase EC 3.5.1.73: carnitinamidase EC 3.5.1.74: chenodeoxycholoyltaurine hydrolase EC 3.5. ...
In enzymology, a D-benzoylarginine-4-nitroanilide amidase (EC 3.5.1.72) is an enzyme that catalyzes the chemical reaction N- ... "Bacteria of the genus Bacillus have a hydrolase stereospecific to the D isomer of benzoyl-arginine-p-nitroanilide". J. ... The systematic name of this enzyme class is N-benzoyl-D-arginine-4-nitroanilide amidohydrolase. Other names in common use ... the two substrates of this enzyme are N-benzoyl-D-arginine-4-nitroanilide and H2O, whereas its two products are N-benzoyl-D- ...
In enzymology, a D-benzoylarginine-4-nitroanilide amidase (EC 3.5.1.72) is an enzyme that catalyzes the chemical reaction N- ... "Bacteria of the genus Bacillus have a hydrolase stereospecific to the D isomer of benzoyl-arginine-p-nitroanilide". J. ... The systematic name of this enzyme class is N-benzoyl-D-arginine-4-nitroanilide amidohydrolase. Other names in common use ... the two substrates of this enzyme are N-benzoyl-D-arginine-4-nitroanilide and H2O, whereas its two products are N-benzoyl-D- ...
3.5.1.72 D-benzoylarginine-4-nitroanilide amidase 3.5.1.73 carnitinamidase 3.5.1.74 chenodeoxycholoyltaurine hydrolase ...
Accepted name: D-benzoylarginine-4-nitroanilide amidase. Reaction: N-benzoyl-D-arginine-4-nitroanilide + H2O = N-benzoyl-D- ... EC 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase. EC 3.5.1.73 carnitinamidase. EC 3.5.1.74 chenodeoxycholoyltaurine ... Bacteria of the genus Bacillus have a hydrolase stereospecific to the D isomer of benzoyl-arginine-p-nitroanilide. J. Bacteriol ... Systematic name: N-benzoyl-D-arginine-4-nitroanilide amidohydrolase. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, ...
EC 3.5.1.72: D-benzoylarginine-4-nitroanilide amidase * EC 3.5.1.73: carnitinamidase ...
aTAME: N alpha-(p-toluene sulfonyl)-L-arginine methyl ester;bBAPNA: benzoyl-Arginine-p-nitroanilide; cSAPNA: N-Succinyl-L-Ala-L ...
... benzoylarginine-2-naphthylamide MeSH D12.125.068.050.100 - benzoylarginine nitroanilide MeSH D12.125.068.050.400 - homoarginine ... benzoylarginine-2-naphthylamide MeSH D12.125.095.104.100 - benzoylarginine nitroanilide MeSH D12.125.095.104.400 - homoarginine ...
... with 144 μl distilled water were assayed to measure trypsin activity using 800 μl 1 mmol l-1 benzoyl-arginine-p-nitroanilide ( ... We used l-alanine-p-nitroanilide as a substrate for aminopeptidase-N. To start the reaction we added 10 μl of the homogenate to ... 1 ml of assay mix (2.0 mmol l-1 l-alanine-p-nitroanilide in one part of 0.2 mol l-1 NaH2PO4/Na2HPO4 buffer no. 1, pH 7 and one ... hydrolysis when incubating 160 μl of homogenate supernatant and 800 μl of 1 mmol l-1 N-glutaryl-l-phenylalanine-p-nitroanilide ...
... but benzoylarginine p-nitroanilide was not hydrolysed. Protease activity has a broad pH profile with a maximum at pH 7.5. Gel ... but benzoylarginine p-nitroanilide was not hydrolysed. Protease activity has a broad pH profile with a maximum at pH 7.5. Gel ... but benzoylarginine p-nitroanilide was not hydrolysed. Protease activity has a broad pH profile with a maximum at pH 7.5. Gel ... but benzoylarginine p-nitroanilide was not hydrolysed. Protease activity has a broad pH profile with a maximum at pH 7.5. Gel ...
The Michaelis parameters for the hydrolysis of L-benzoylarginine p-nitroanilide and of benzyloxy-carbonyl-lysine nitrophenyl ...
D-benzoylarginine-4-nitroanilide amidase (substance). Code System Preferred Concept Name. D-benzoylarginine-4-nitroanilide ...
... benzoylarginine nitroanilide bapp = bleomycin, doxorubicin, cisplatin, prednisone barb = barbiturate barbital = phenobarbital ... benzoylarginine ethyl ester baep = brainstem auditory evoked potential baer = brainstem auditory evoked response baha = bone ... benzoylarginine 2 naphthylamide banf = bilateral acoustic neurofibromatosis bao = basal acid output bao = basal gastric acid ...
... were subjected to hydrophobic chromatography and the pooled fraction with reactivity to N-alpha benzoylarginine-4-nitroanilide ...
MacLeod, A. M., MASON, R. J., POWER, D. A., MATHER, A. J., EDWARD, N., Stewart, K. N., SHEWAN, W. G., Urbaniak, S. & CATTO, G. R. D., May 1985, In : Transplantation. 39, 5, p. 520-523 4 p.. Research output: Contribution to journal › Article ...
GCF was analyzed for activity against benzoyl-L-arginine-p-nitroanilide in the presence (BAPNA w/gly-gly) and the absence ( ... GCF was analyzed for activity against benzoyl-L-arginine-p-nitroanilide in the presence (BAPNA w/gly-gly) and the absence ( ... GCF was analyzed for activity against benzoyl-L-arginine-p-nitroanilide in the presence (BAPNA w/gly-gly) and the absence ( ... GCF was analyzed for activity against benzoyl-L-arginine-p-nitroanilide in the presence (BAPNA w/gly-gly) and the absence ( ...
Benzoylarginine Nitroanilide *Bupivacaine *Carbanilides + *Carboxin *Encainide *Flutamide *Prilocaine *Propanil * ...
Benzoyl-arginine-p-nitroanilide (Bz-Arg-pNan) was hydrolyzed by the saline extract. ...
Benzoylarginine Nitroanilide, Monosodium Salt, Monohydrochloride. Biliary Sludge. Casein A. Avazyme. Guanidines. Homoarginine. ... Also, guanidinated casein inhibited tryptic hydrolysis of benzoyl-L-arginine p-nitroanilide to a lesser extent than ...Continue ...
... three times the rate obtained with benzoyl arginine ethyl aster and twenty times the rate of benzoyl arginine p-nitroanilide) ( ...
... 72 D-benzoylarginine-4-nitroanilide amidase. EC 3.5.1.73 carnitinamidase. EC 3.5.1.74 chenodeoxycholoyltaurine ...
3 M solution of benzoyl-arginine p-nitroanilide. Under the enzymatic action of the activated plate, this compound did liberate ... 115, 206 (1966) is based on the cleavage of the above nitroanilide with liberation of p-nitroanilide which is measured ... 3 M solution of benzoylarginine ethyl ester which caused the practically quantitative liberation of the benzoylarginine ( ... the phosphate buffer and the enzymatic activity of the operative coating was determined with benzoyl-arginine p-nitroanilide ( ...
D-benzoylarginine-4-nitroanilide amidase 3.5.1.73 Carnitinamidase 3.5.1.74 Chenodeoxycholoyltaurine hydrolase 3.5.1.75 ...
Harvested bikunin retained its trypsin inhibitory activity (L-benzoylarginine-p-nitroanilide assay). Nevertheless hematologists ...
Benzoyl-arginine-p-nitroanilide (Bz-Arg-pNan) was hydrolyzed by the saline extract. ...
Benzoylarginine Nitroanilide. *Benzoylarginine-2-Naphthylamide. *Homoarginine. *NG-Nitroarginine Methyl Ester. *Nitroarginine. ...
The keratinase of strain kr2 was active on azokeratin, azocasein, benzoyl-arginine-p-nitroanilide and Ala-Ala-p-nitroanilide as ...
... benzoyl-arginine p-nitroanilide (Bz-Arg-Nan), tosyl-arginine p-nitroanilide (Tos-Arg-Nan), acetyl-leucyl-arginine p- ... and D-valyl-leucyl-arginine p-nitroanilide (D-Val-Leu-Arg-Nan), and the N alpha-substituted L-arginine ester: benzoyl-arginine ... nitroanilide (Ac-Leu-Arg-Nan), acetyl-phenylalanyl-arginine p-nitroanilide (Ac-Phe-Arg-Nan), benzoyl-phenylalanyl-arginine p- ... nitroanilide (Bz-Phe-Arg-Nan), tosyl-phenylalanyl-arginine p-nitroanilide (Tos-Phe-Arg-Nan), ...
The tryptic activity of the samples was estimated using an 8 mM benzoyl-arginine-p-nitroanilide (BApNA) substrate prepared in ...
... benzoyl-arginine-p-nitroanilide (BAPA) [11]. The activity of D-BAPA-ase was highest at low NaCl concentration (100 mM) and ...
The substrate N-benzoyl arginine para nitroanilide was dissolved in distilled dimethyl formamide to get following different ... N-benzoyl DL arginyl para nitro anilide (DL-BAPNA) for trypsin and N-benzoyl L-tryosyl para nitro anilide (BTPNA) for ...
Benzoylarginine Nitroanilide D2.92.146.113.200 Benztropine D4.75.80.875.99.722.270 D3.605.84.500.722.270 Benzydamine D3.438. ...
  • In enzymology, a D-benzoylarginine-4-nitroanilide amidase (EC 3.5.1.72) is an enzyme that catalyzes the chemical reaction N-benzoyl-D-arginine-4-nitroanilide + H2O ⇌ {\displaystyle \rightleftharpoons } N-benzoyl-D-arginine + 4-nitroaniline Thus, the two substrates of this enzyme are N-benzoyl-D-arginine-4-nitroanilide and H2O, whereas its two products are N-benzoyl-D-arginine and 4-nitroaniline. (wikipedia.org)
  • Site-directed mutagenesis of α-NGF to alter the N-terminus and three residues in loop 7, a region that contributes to the catalytic center, restored substantial catalytic activity against N-benzoyl arginine-p-nitroanilide as substrate in two derivatives although they were not as active as recombinant γ-NGF. (elsevier.com)
  • The Michaelis parameters for the hydrolysis of L-benzoylarginine p-nitroanilide and of benzyloxy-carbonyl-lysine nitrophenyl ester at 25 degrees C, and I 0.1 at several pH values catalysed by chymopapain A, papaya proteinase omega, papain (EC 3.4.22.2) and actinidin (EC 3.4.22.14) were determined. (biochemj.org)
  • GCF was analyzed for activity against benzoyl-L-arginine-p-nitroanilide in the presence (BAPNA w/gly-gly) and the absence (BAPNA w/o gly-gly) of glycyl-glycine and against MeOSuc-Ala-Ala-Pro-Val-pNA and Suc-Ala-Ala-Pro-Phe-pNA for neutrophil serine proteinases activity (elastase and cathepsin G, respectively). (elsevier.com)
  • The systematic name of this enzyme class is N-benzoyl-D-arginine-4-nitroanilide amidohydrolase. (wikipedia.org)