Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
Compounds based on a 7-membered heterocyclic ring including an oxygen. They can be considered a medium ring ether. A natural source is the MONTANOA plant genus. Some dibenzo-dioxepins, called depsidones, are found in GARCINIA plants.
The field of information science concerned with the analysis and dissemination of data through the application of computers.
The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Time period from 2001 through 2100 of the common era.
Six-carbon alicyclic hydrocarbons.
Dissertations embodying results of original research and especially substantiating a specific view, e.g., substantial papers written by candidates for an academic degree under the individual direction of a professor or papers written by undergraduates desirous of achieving honors or distinction.
Individuals enrolled in a school or formal educational program.
Individuals enrolled in a school of medicine or a formal educational program in medicine.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Individuals enrolled a school of dentistry or a formal educational program in leading to a degree in dentistry.
Individuals enrolled in a school of pharmacy or a formal educational program leading to a degree in pharmacy.
Benzopyrroles with the nitrogen at the number two carbon, in contrast to INDOLES which have the nitrogen adjacent to the six-membered ring.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
The rate dynamics in chemical or physical systems.
Organisms, biological agents, or biologically-derived agents used strategically for their positive or adverse effect on the physiology and/or reproductive health of other organisms.
Tricyclic ethylene-bridged naphthalene derivatives. They are found in petroleum residues and coal tar and used as dye intermediates, in the manufacture of plastics, and in insecticides and fungicides.
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
The science that investigates the principles governing correct or reliable inference and deals with the canons and criteria of validity in thought and demonstration. This system of reasoning is applicable to any branch of knowledge or study. (Random House Unabridged Dictionary, 2d ed & Sippl, Computer Dictionary, 4th ed)
A plant genus of the family POLYGALACEAE that contains onjisaponins, xanthones, pyrones, and benzophenones. The name is similar to other snakeroots such as ASARUM; SANICULA; ARISTOLOCHIA; AGERATINA; and others.
A plant genus of the family ACORACEAE, order Arales, subclass Arecidae most notable for Acorus calamus L. root which contains asarone and has been used in TRADITIONAL MEDICINE.
A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator of transcription. It interacts with key regulatory proteins such as TATA-BINDING PROTEIN; TFIIB; and ADENOVIRUS E1A PROTEINS.

Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin. (1/21)

The modifying effects of dietary administration of the citrus limonoids obacunone and limonin on azoxymethane (AOM)-induced colon tumorigenesis were investigated in two experiments in male F344 rats. In a pilot study, we examined the modifying effects of obacunone and limonin on AOM-induced (20 mg/kg body wt, once a week for 2 weeks) formation of aberrant crypt foci (ACF). Dietary feeding of both compounds at dose levels of 200 and 500 p.p.m. during AOM exposure for 4 weeks ('initiation' feeding) or after AOM treatment for 4 weeks ('post-initiation' feeding) significantly inhibited ACF formation (55-65% reduction by 'initiation' feeding, P < 0.001; 28-42% reduction by 'post-initiation' feeding, P < 0.05-0.002). In a long-term study designed to confirm the protective effects of obacunone and limonin on ACF development, one group was treated with AOM alone and another four groups received the carcinogen treatment plus diets containing 500 p.p.m. test compounds for 3 weeks (initiation phase) or 29 weeks (post-initiation phase). Two groups were treated with obacunone or limonin alone (500 p.p.m. in diet) and one group was maintained on the basal diet. At the termination of the study, dietary exposure to obacunone or limonin during the initiation phase was found to have significantly reduced the incidence of colonic adenocarcinoma (72 versus 25 or 6%, P = 0.004 or 0.00003). Obacunone or limonin feeding during the post-initiation phase also reduced the frequency of colonic adenocarcinoma (72 versus 13%, P = 0.0002). Our results suggest that the citrus limonoids obacunone and limonin might be useful for the prevention of human colon cancers.  (+info)

Determination of the stereochemistry of (-)-koninginin A by an X-ray analysis of its synthetic sample. (2/21)

The absolute configuration of (-)-koninginin A [10-hexyl-11, 12-dioxatricyclo[7.2. 1.0<1 ,6>]dodecane-2,5-diol (1)], the antibiotic metabolite of Trichoderma koningii and T. harzianum, was determined as 1S, 2R, 5S, 6S, 9S, 10S by an X-ray crystallographic analysis of its synthetic sample coupled with the established stereochemical outcome of Sharpless asymmetric dihydroxylation used as the key reaction to prepare intermediate 4.  (+info)

Effects of KW-3635, a novel dibenzoxepin derivative of a selective thromboxane A2 antagonist, on human, guinea pig and rat platelets. (3/21)

We examined the binding of [3H]U-46619, a thromboxane A2 agonist, to human and guinea pig platelets and the binding of [3H]SQ 29,548, a thromboxane A2 antagonist, to human, rat and guinea pig platelets. KW-3635 (sodium (E)-11-[2-(5,6-dimethyl-1- benzimidazolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-c arboxylate monohydrate) concentration-dependently inhibited the [3H]U-46619 binding to human and guinea pig platelets with inhibition constants of 1.2 nM and 2.7 nM, respectively. KW-3635 also potently inhibited the [3H]SQ 29,548 binding to human and guinea pig platelets with inhibition constants of 1.9 nM and 3.2 nM, respectively. In contrast, KW-3635 was less active against thromboxane A2/prostaglandin H2 receptors in rat platelets with an inhibition constant of 97 nM. KW-3635 at 10(-5) M did not antagonize various receptors including prostaglandin E2, prostaglandin I2 and neurotransmitters. In addition, 10(-5) M KW-3635 did not alter the prostaglandin D2-induced cAMP accumulation in EBTr cells. KW-3635 was inactive towards thromboxane synthase, cyclooxygenase and prostaglandin I2 synthase up to 10(-5) M. KW-3635 slightly inhibited 5-lipoxygenase with an IC50 value of 71 microM. These data indicate that KW-3635 is a potent and selective non-prostanoic thromboxane A2 antagonist, and it can recognize the species differences in thromboxane A2/prostaglandin H2 receptors.  (+info)

An efficient synthesis of 2-benzoxepines from Morita-Baylis-Hillman adducts using heterogeneous recyclable catalysts. (4/21)

2-Benzoxepines have efficiently been synthesized from Morita-Baylis-Hillman adducts, alkyl 3-aryl-3-hydroxy-2-methylenepropanoates by treatment with HCHO catalyzed by silica supported perchloric acid (HClO4.SiO2) or Amberlyst-15 in CH2Cl2 under reflux for a short period of time (1.5-2.5 h). The catalyst can be recovered and recycled. The antibacterial properties of the new 2-benzoxepines were studied but no activity was found.  (+info)

In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids. (5/21)

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Obacunone represses Salmonella pathogenicity islands 1 and 2 in an envZ-dependent fashion. (6/21)

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Centrally mediated inhibitory effect of 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride (KW-5805) on gastric acid secretion in rats. (7/21)

KW-5805, 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride, is a new tricyclic compound with antiulcer activities. Its effect on stimulated gastric acid secretion was investigated in the perfused stomach of anesthetized rats. KW-5805 at 0.3-10 mg/kg, i.v., dose-dependently inhibited gastric acid secretion stimulated by 2-deoxy-D-glucose (2-DG). On the other hand, the compound at 10-20 mg/kg, i.v., exerted a moderate decrease in gastric acid secretion stimulated by bethanechol; and at 10 mg/kg, i.v., it produced no change in gastric acid secretion evoked peripherally by vagal electrical stimulation. When applied intracerebroventricularly at 1-5 micrograms/rat, this compound dose-relatedly reduced gastric acid secretion stimulated by 2-DG. Three main metabolites (KF-10504, KF-9530 and KF-10847) of KW-5805 at 1 mg/kg, i.v., caused no significant decrease in gastric acid secretion stimulated by 2-DG. Doxepin, a tricyclic compound, definitely depressed the 2-DG stimulated gastric acid secretion at 1 mg/kg, i.v. It is suggested that intravenous administration of KW-5805 inhibits gastric acid secretion stimulated by 2-DG, mainly via centrally mediated mechanisms, and that biotransformation of KW-5805 to the metabolites contributes little to the development of the antisecretory effect.  (+info)

Biological modification of trichothecene mycotoxins: acetylation and deacetylation of deoxynivalenols by Fusarium spp. (8/21)

Attempts were made to elucidate the acetyl transformation of novel trichothecene mycotoxins, 3a,7a,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one (deoxynivalenol) and its derivatives, by trichothecene-producing strains of Fusarium nivale, F. roseum, and F. solani. In the peptone-supplemented Czapek-Dox medium, F. roseum converted 3a-acetoxy-7a,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one (3-acetyldeoxynivalenol) to deoxynivalenol. 3-Acetyldeoxynivalenol was also deacetylated by intact mycelia of the three strains in sugar-free Czapek-Dox medium. The growing F. nivale acetylated deoxynivalenol to afford a small amount of 3-acetyldeoxynivalenol. 3a,7a,15-Triacetoxy-12,13-epoxytrichothec-9-en-8-one (7,15-diacetyl-deoxynivalenol), which was then deacetylated to give 7a-acetoxy-3a,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one (7-acetyldeoxynivalenol). It was noted that the ester at C-7 was not hydrolyzed by the fungal mycelium.  (+info)

Botrytis blight is a very destructive disease caused by Botrytis spp., infecting flowers, trees, vegetables and fruits. Twelve new compounds were prepared by the reaction of potassium N-aryl-sulfonyldithiocarbimates with Morita-Baylis-Hillman derivatives bearing phenyl and furyl groups. These are the first examples of allyldithiocarbimate anions and were isolated as tetraphenylphosphonium salts. The new compounds were characterized by HRMS, NMR and Infrared spectroscopy. Further, the structures of three allyldithiocarbimates were determined by single crystal X-ray diffraction. The compounds are isostructural and crystallize in the space group P21/c of the monoclinic system, and the allyldithiocarbimate anions present Z configuration. All the compounds were active against Botrytis cinerea. The best results were achieved with the tetraphenylphosphonium (Z)-3-(furan-2-yl)-2-(methoxycarbonyl)allyl-(4-chlorophenylsulfonyl)dithiocarbimate (IC50 38 μM). ...
Morita-Baylis-Hillman adduct shows in vitro activity against Leishmania (Viannia) braziliensis associated with a reduction in IL-6 and IL-10 but independent of nitric oxide - Volume 140 Issue 1 - F. M. AMORIM, Y. K. S. RODRIGUES, T. P. BARBOSA, P. L. N. NÉRIS, J. P. A. CALDAS, S. C. O. SOUSA, J. A. LEITE, S. RODRIGUES-MASCARENHAS, M. L. A. A. VASCONCELLOS, M. R. OLIVEIRA
Experimental and analytical studies for natural and synthetic samples under extreme conditions have advanced considerably in the past few years. Increased spatial, temporal and energy resolution, new mapping and imaging methods, novel spectroscopic techniques and new experimental devices are extending our research scales previously inaccessible. These significantly promote the analysis of mineral samples as well as for in situ diagnostics in experiments at high temperature, pressure, or stresses. This session welcomes all contributions that highlight such novel developments, including fresh results that have profited from such new experimental and analytical approaches ...
Known as: 4H-3,15a-Epoxy-1-benzoxepino(6,7:6,7)indeno(1,2-b)indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R-(3alpha,5balpha,7abeta,13balpha,13cbeta,15aalpha))- ...
A new study revealed that artificial sweeteners may be causing weight gain and other health issues. An expert claims that these sweeteners disturb the bodys ability to count calories and might simulate hunger.
A highly enantioselective addition of cyclohexenone to different aldehydes (asymmetric Morita-Baylis-Hillman reaction) catalyzed by octahydro-BINOL-derived Brønsted acid (669172) was reported by Schaus (Scheme 15). Important for achieving high enantioselectivity were both the partial saturation and substitution at the 3,3-positions of the BINOL derivative.1. ...
This course surveys the role of disturbed neural mechanisms on the development of psychological disorders such as autism and schizophrenia. The relationship of neural disturbances to genetic variations, and to cognitive and affective abnormalities, will also be addressed. Methods for investigating mechanisms and evaluating treatments will be critically evaluated. Prerequisites: P326 (Behavioral Neuroscience) or P346 (Neuroscience) are required before enrolling, or equivalent. This course counts as an advanced neuroscience course for the Neuroscience Major as well as toward a BA or BS in Psychological and Brain Sciences ...
Documenting mass spectral data is a fundamental aspect of accepted protocols. In this report, we contrast MS(n) sequential disassembly spectra obtained from natural and synthetic glycan epitopes. The epitopes considered are clusters found on conjugate termini of lipids and N- and O-glycans of proteins. The latter are most frequently pendant through a CID-labile HexNAc glycosidic linkage. The synthetic samples were supplied by collaborating colleagues and commercial sources and usually possessed a readily released reducing-end linker, a by-product of synthesis. All samples were comparably methylated, extracted, and MS(n) disassembled to compare their linkage and branching spectral details. Both sample types provide B-ion type fragments early in a disassembly pathway and their compositions are a suggestion of structure. Further steps of disassembly are necessary to confirm the details of linkage and branching. Included in this study were various Lewis and H antigens, 3- and 6-linked ...
4H-​3,​15a-​Epoxy-​1-​benzoxepino[6,​7:6,​7]​indeno[1,​2-​b]​indol-​4-​one, 2,​3,​5b,​6,​7,​7a,​8,​13,​13b,​13c,​14,​15-​dodecahydro-​5b-​hydroxy-​2,​2,​13b,​13c-​tetramethyl-​, [3R-​(3α,​5bα,​7aβ,​13bα,​13cβ,​15aα)​]​-; (+)​-​Paspalinine; 11-​Hydroxypaspalicine; Paspalinin; ...
Mle ni ri z jagodami nedelja, 17. maj 2020 @ 16:02 CEST Uporabnik: Sonce Sestavine: 1 l mleka 1 zavitek vanilijevega sladkorja Cimet Pomaran na lupinica 30 g masla 300 g ri a 1 kg jagod Limonina lupinica 2 lici limoninega soka 150 g sladkorja 175 ml pomaran nega soka 2 lici kisle smetane Potek: Pristavite mleko, dodajte vanilijev sladkor, cimet in pomaran no lupino ter po akajte da zavre. V kozici razpustite maslo in prepra ite ri , da zrnca posteklenijo. Prilijte toliko vro ega mleka, da je ri pokrit. Kuhajte v posodi brez pokrova 25 do 30 minut. Postopoma prilivajte e preostalo mleko. Ve krat preme ajte. Medtem o istite jagode in jih nare ite na etrtine. S pali nim me alnikom sesekljajte 250 g jagod, limonin sok, limonino lupinico in 50 g sladkorja. Pristavite pomaran ni sok in 100 g sladkorja. Ko zavre, ga prilijte k ri u in kuhajte e 5 min, da teko ina povre. Ri naj se nekoliko ohladi. Med ri prime ajte preostale narezane jagode in kislo smetano. Ri ponudite z jagodnim prelivom. Komentarji ...
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Zuschriften DOI: 10.1002/ange.200900351 Multicomponent Reactions Enantioselective Synthesis of b-Iodo Morita-Baylis-Hillman Esters by a Catalytic Asymmetric Three-Component Coupling Reaction** Bidyut Kumar Senapati, Geum-Sook Hwang, Sungil Lee, and Do Hyun Ryu* Dedicated to Professor Sung Ho Kang on the occasion of his 60th birthday Optically active a-methylene-b-hydroxy carbonyl derivatives can be prepared by the asymmetric Morita-Baylis-Hillman (MBH) reaction.[1] These derivatives are useful chiral building blocks for biologically active molecules and natural products because of their multifunctional composition.[2] Even with recent advances in this area, asymmetric synthesis of bsubstituted MBH products such as b-branched MBH ketones or esters have not been successful by this method.[2] One efficient route to give various b-branched MBH products[3] can be achieved through the cross-coupling reaction of chiral b-halo MBH products (Scheme 1). The presence of a halogen Scheme 1. Enantioselective ...
Several series of ligands, designed to chelate silver(I) specifically in the presence of base metals, have been synthesised. The ligands include: - dithiodiamide compounds, prepared by the condensation of acetanilide derivatives with 1,2-dibromoethane; propanenitrile and propanoic ester derivatives prepared from pyridine-2-carbaldehyde via the Morita-Baylis-Hillman reaction; and novel malonamide ligands from the reaction of diethyl malonate with a range of primary amines. The malonamide derivatives were prepared under both conventional thermal and microwave-assisted conditions, the latter proving to be highly efficient. The ligands were all characterised using a combination of spectroscopic and, where appropriate, elemental analysis; in one case, the structural assignment was confirmed by single-crystal X-ray analysis. The fragmentation patterns in the electron-impact mass spectra of the malonamide derivatives have been explored using high-resolution and meta-stable peak scanning ...
Hypercholesterolemia induces adhesion of blood-borne monocytes to vascular endothelium and their subsequent migration into the intima, where foam cell lesions subsequently develop. The regulating mechanisms for the adhesion and migration are unclear. In this study, a specific thromboxane A2 (TXA2) synthetase inhibitor, UK-38485, was used to treat rabbits fed an atherogenic diet to determine whether inhibition of TXA2, the major metabolite of arachidonic acid in monocytes, affects lesion development. Rabbits were fed a diet supplemented with 2% cholesterol and 8% peanut oil for 12 weeks with or without UK-38485 at a dosage that maintained 80% to 90% inhibition of TXA2 formation in serum. The treatment with UK-38485 had no effect on total serum cholesterol. Both the treated and untreated groups developed subpopulations of high and low responders with respect to the extent of lesion coverage, forming a bimodal distribution. The treatment with UK-38485 significantly (p less than 0.001) reduced the ...
Unchanged ethotoin and 11 metabolic products of ethotoin were detected in the urine of subjects (2 men and 1 woman) receiving ethotoin. Nine of these products were identified by comparison of their retention times and mass spectra with those of authentic synthetic samples. Hydroxylation of the hydantoin ring at the 5-position produced 5-hydroxyethotoin and 5-hydroxy-5-phenylhydantoin. Aryl hydroxylation resulted in the formation of p-hydroxyethotoin, o-hydroxyethotoin, m-hydroxyethotoin, 3-methoxy-4-hydroxyethotoin, and 3,4-dihydroxyethotoin. Most of these were excreted as the glucuronide conjugate. A dihydrodiol of ethotoin and 3-ethyl-5-hydroxy-5-(4-hydroxyphenyl)hydantoin were isolated along with unchanged ethotoin and 5-phenylhydantoin. 2-Phenylhydantoic acid was also isolated and was shown to have the (R)(-)-configuration. ...
The report generally describes limonin, examines its uses, production methods, patents. Limonin market situation is overviewed; limonin manufacturers
An 18-year-old has complained of seizures in an Indian hospital. It turned out that the teen actually had a parasite in his brain, as per a case study that was published on Tuesday in the Journal of Medicine, in New England. More specifically, a tapeworm larvae infestation in the brain caused the death of the young man.. Dr. S. Zafar Abbas and Dr. Nishanth Dev from the ESIC Medical College and Hospital in Faridabad has said that the patient, who came into the ER with swelling at his right eye, also complained of tonic-clonic seizures. This kind of seizures is also known as grand mal seizures, which are neural disturbances that are known to cause stiffened muscles and, sometimes, loss of consciousness.. His parents stated that their son had been in pain in his right groin for about a week. After a physical exam, its been shown that he had tenderness in the right testis and that he presented signs of confusion. ...
臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。. To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of NTU Repository with Academic Hub to form NTU Scholars.. ...
अलीबाबा 3 Dihydro 1h Inden 2 एमाइन दुनिया की अग्रणी निर्यात उत्पादों बाजार है, आपको उच्च गुणवत्ता पूर्ण 3 Dihydro 1h Inden 2 एमाइन की आपूर्ति जानकारी का चयन देख सकते हैं, आप पा सकते हैं इसके अलावा थोक ऑनलाइन 3 Dihydro 1h Inden 2 एमाइन बातचीत, नवीनतम 3 Dihydro 1h Inden 2 एमाइन मूल्य उद्धरण और विश्वास के साथ खरीद।
109475-73-2 - UECZYPYRMGJCSA-UHFFFAOYSA-N - Butyramide, 2-(diethylamino)-N-(1,1,3,3-tetramethylbutyl)-, hydrochloride - Similar structures search, synonyms, formulas, resource links, and other chemical information.
300 g jagod zmeljemo v me alniku, dodamo sladkor, limonin sok in nato 3 dcl stepene sladke smetane. Ostale jagode nare emo, manj e na 4 dele, ve je pa na 6 delov, ter jih zame amo med zmlete jagode. Jagodovo peno porazdelimo po a ah, okrasimo z biskvitnimi pali icami ali pi koti, narezanimi jagodami in stepeno smetano.. 0 komentarjev.. ...
invaders which may compete for nutrients or inhibit S. cepivorum. When placed on the epidermis of healthy onion roots T. koningii (Tr5) ...
Buy high quality 2,2-Bis[4-[2-(diethylamino)ethoxy]phenyl]-1,2-diphenylethanone Dihydrochloride 1391054-64-0 from toronto research chemicals Inc.
DEAE diethylamine column screening method development housing exchange biomolecules chemistry virus VLP proteins pDNA
DEAE diethylamine column screening method development housing exchange biomolecules chemistry virus VLP proteins pDNA
ethyl 4-(diethylamino)benzoate 10287-54-4 NMR spectrum, ethyl 4-(diethylamino)benzoate H-NMR spectral analysis, ethyl 4-(diethylamino)benzoate C-NMR spectral analysis ect.
CAS 69-44-3 o-Cresol,4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-,dihydrochloride * Amodiaquin dihydrochloride * Camoquin hydrochloride * 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol dihydrochloride * Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-, dihydrochloride msds toxicity property
3-(2-(Diethylamino)ethyl)-5-methylisoxazole citrate | C16H26N2O8 | CID 13779 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
20809-09-0 - FCGHGGBUEJQLIJ-UHFFFAOYSA-N - Propiophenone, 2-(2-(diethylamino)ethoxy)-5-methyl-, hydrochloride - Similar structures search, synonyms, formulas, resource links, and other chemical information.
[65 Pages Report] Check for Discount on tris(diethylamino)phosphine Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
Quetiapine EP Impurity N ;. Quetiapine Dipiperazine Diether Impurity ;. 4-[2-[2-(4-Dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethyl]-1-[(2-hydroxyethoxyl)ethyl]-piperazine trihydrochloride ;. CAS # 1800291-86-4 (base) ;. C27H37N5O2S (base) ; MW: 495.68 ;. C29H44Cl3N5O3S (3HCl salt) ; Mol. Wt.: 649.12 ; ...
This study examined the effects of highly palatable food during adolescence on the psycho-emotional and neural disturbances caused by early life stress experience in female rats. Female Sprague-Dawley pups were separated from dam for 3 h daily during the first two weeks of birth (MS) or left undisturbed (NH). Half of MS females received free access to chocolate cookies in addition to ad libitum chow from postnatal day 28. Pups were subjected to the behavioral tests during young adulthood. The plasma corticosterone response to acute stress, ΔFosB and brain-derived neurotrophic factor (BDNF) levels in the brain regions were analyzed. Total caloric intake and body weight gain during the whole experimental period did not differ among the experimental groups. Cookie access during adolescence and youth improved anxiety-/depression-like behaviors by MS experience. ΔFosB expression was decreased, but BDNF was increased in the nucleus accumbens of MS females, and ΔFosB expression was normalized and ...
TY - JOUR. T1 - Observation of bicarbonate in calcite by NMR spectroscopy. AU - Feng, Jian. AU - Lee, Young J.. AU - Reeder, Richard J.. AU - Phillips, Brian L.. PY - 2006/5. Y1 - 2006/5. N2 - We show that the signal observed in 13C{1H} cross-polarization magic-angle-spinning (CP/MAS) NMR spectra of synthetic calcite precipitated at room temperature arises from bicarbonate ion. Although this peak occurs at the same chemical shift as for the bulk carbonate signal, its observation by CP/MAS indicates that it corresponds to carbonate associated with H. The variation in the CP/MAS intensity with contact time shows oscillations characteristic of C-H pairs separated by 1.9(1) Å and remote from other H, consistent with bicarbonate. 13C{1H} heteronuclear correlation spectra indicate that the hydrogen in the bicarbonate groups gives a relatively narrow 1H NMR signal at +7.4 ppm. A peak at this chemical shift is also observed in direct-observe 1H MAS NMR spectra of the synthetic sample, and also in ...
Elemental selenium has been extensively quantitatively measured in sediments; however, its physical composition is largely unknown, despite it being the dominant selenium species in some reducing environments. Here, for the first time, it is shown that small, cyclic selenium compounds can account for a quantitatively-relevant fraction of the total elemental selenium present. A new method was developed to analyze for cyclooctaselenium (Se8) in both synthetic samples and selenium-impacted sediments. Despite some analytical limitations, this gas chromatography-mass spectrometry (GC-MS) method is the first GC-MS method developed to identify and quantify Se8 in sediments. Once this method was established, it was then applied to more complex systems: first, the identification of compounds in mixed selenium-sulfur melt solutions, and then the determination of SenSm in selenium-impacted sediments. Despite complications arising from pronounced fragmentation in the ion source, assignment of definitive ...
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Inquiry for China 2-Chloro-N-[2-Diethylamino]ethyl]-4-Quinoline Carboxamine of Anhui Tianrun Chemical Industry Stock Co., Ltd. , China 2-Chloro-N-[2-Diethylamino]ethyl]-4-Quinoline Carboxamine Suppliers & Manufacturers
3-(DIETHYLAMINO)BENZOIC ACID 97-20-1 safety info, 3-(DIETHYLAMINO)BENZOIC ACID chemical safety search, Chemical 3-(DIETHYLAMINO)BENZOIC ACID safety technical specifications ect.
1 mCi quantities of [Terminal Methylenes-3H(N)]-Spermidine Trihydrochloride are available for your research. Application of [3H]Spermidine can be found in: possible novel mechanism underlying temperature-dependent uptake in nuclear fractions in (murine) brain research, endogenous indoles as novel polyamine site ligands at the NMDA receptor complex in brain research, lysine-spermine conjugate inhibiting polyamine transport and cell growth when given with DFMO in experimental cell research, etc.. ...
The researchers found that the human body can absorb and exploit the long-acting limonoids called limons, which in citrus fruits is contained equally as much as vitamin C. In citruses, Limons are present in the form of limonin - glycoside, e.g. it is bound to a molecule of glucose (sugar). Our bodies easily absorb this compound, dissolving the sugar and releasing limonin. Moreover, scientists have found that red grapefruit pulp contains in its pulp glucarates, compounds that protect against breast cancer ...
Regional Library resource containing information dedicated to assisting people in obtaining and researching Workforce Development Services.
Regional Library resource containing information dedicated to assisting people in obtaining and researching Workforce Development Services.
Nine new phragmalin-type limonoids, heytrijumalins A-I (1-9), together with the known 15-acetyltrichagmalin E (10) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compounds 6 and 10 showed insecticidal activity at 100 ppm, with corrected mortalities of 82.94% and 96.02%, respectively. Compounds 2 and 10 showed weak cytotoxicity against HL-60 and A-549 human tumor cell lines, with IC50 values ranging from 14.55 to 25.27 mu M ...
adenosine triphosphate (7-(diethylamino)coumarin-4-yl)methyl ester: a caged form of ATP for light controlled transcription reactions in vitro; structure in first source
Your doctor might prescribe Nexium to treat various conditions, but the primary uses of the medication are treating GERD or acid reflux and stomach ulcers caused by anti-inflammatory medications. Esomeprazole also heals damaged stomach and esophageal linings, and long-acting Nexium can be swallowed in capsule form, ingested through a feeding tube or mixed with water or food by breaking apart the capsules and mixing the granules in soft foods like applesauce.[3]. Typical dosage is one capsule daily, and you shouldnt chew the granules so that you benefit from the time-released properties of the medication. Esomeprazole therapy might take several weeks before you experience significant relief. You should call your doctor if you experience side effects or your symptoms get worse, but dont stop taking the medicine if your condition improves until your doctor tells you to do so.. ...
China Hot Sale Portable 3kw-5kw Gasoline Generator, Find details about China Power Generator, Portable Generator from Hot Sale Portable 3kw-5kw Gasoline Generator - Jinan Lvneng Power Machinery Equipment Co., Ltd.
Za vse tiste, ki jutri godujete:. ena hitra sladica, ki se vam bo prilegla. Skutin kolač. 250g zmehčanega masla, 200g sladkorja, 4 jajca, 3 žlice limoninega soka, 1 žlička limonine lupinice, 150g pšeničnega zdroba, 1 pecilni prašek, 1 vaniljev puding, 750g pasirane skute, 1 pločevinka breskev. Pečico segrejemo na 180 stopinj. Tortni model namažemo z maslom ali oljem. V skledi z električnim mešalnikom kremasto zmešamo zmehčano maslo in sladkor. Med mešanjem dodamo jajca, limonin sok in lupinico. V drugi posodi skupaj zmešamo zdrob, pecilni prašek in prašek za vanilijev puding. Vse to dodamo jajčno masleni masi. Na koncu umešamo še pasirano skuto. Testo vlijemo v model in pečemo približno 1 uro. Na koncu kolač obložimo z narezanimi breskvami.. Sama sem kolač pekla malo več kot uro. Izgleda slastno in en kos je že zginil-za probo. Ampak bo boljši ohlajen.. Lep praznik vsem.. ...
Sucro 1000 MG Syrup is an antiulcer agent which is used to treat ulcers in the intestine. It should be taken at least 1 hour before food. It may delay the absorption of many medicines. The oral suspension form may increase the blood glucose levels in diabetic patients. Buy Sucro 1000 MG Syrup Online. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Download Practo app & get your medicines home delivered.
Tacrolimus 8-Propyl Analog (USP) ;. Dihydro Tacrolimus ;. Dihydro FK-506 ;. Tsukubamycin B ;. CAS # 104987-30-6 ;. C44H71NO12 ;. MW: 806.03 ;. ...
Uncorrected OCR) Abstract of the thesis entitled. A STUDY OF THE CHEMICAL AND PHYSICAL. PROPERTIES OF EPOXIDIZED AND HYDRATED. CONJUGATED LINOLEIC ACID. submitted by. Lam NgorWai. for the degree of Master of Philosophy. at The University of Hong Kong. in December 2002. A study was carried out on a synthetic sample of conjugated linoleic acid. [18:2(9Z,llE)] (CLA), which was prepared from ricinoleic acid (isolated from the. castor-oil plant, Ricinus cummunis). The synthesis of CLA involved the substitution. of the hydroxyl group in ricinoleic acid by bromide followed by dehydrobromination. to give the requisite CLA isomer after purification.. CBr4/ CH2CI2/ PPh3 0-5?. i) KOH / EtOH (95 %). Br Z reflux. R1~R2 ii) BF3-MeOH / MeOH reflux. E Z ~~R2 R1----. (1 ). The synthetic 18:2(9Z,11E) was epoxidized usmg either m-. chloroperoxybenzoic acid, methyltrioxorhenium/hydrogen peroxide, dimethyl. dioxirane or Novozyme 43S?hydrogen peroxide to give the corresponding. monoepoxy lYiz. methyl ...
Reilly SM, Chiang SH, Decker SJ, et al. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. PMID: 23396211.. Bell J. Amlexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig. 2005;25(9):555-66. PMID: 17532700.. Landriscina M, Prudovsky I, Mouta Carreira C, et al. Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro. J Biol Chem. 2000 Oct 20;275(42):32753-62. PMID: 10921913.. Shishibori T, Oyama Y, Matsushita O, Yet al. Three distinct anti-allergic drugs, amlexanox, cromolyn and tranilast, bind to S100A12 and S100A13 of the S100 protein family. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9. PMID: 10051426.. Makino H, Saijo T, Ashida Y, et al. Mechanism of action of an antiallergic agent, amlexanox (AA-673), in inhibiting histamine release from mast cells. Acceleration of cAMP generation and inhibition of ...
Carbanilic acid, 2,6-dichloro-4-ethoxy-, 2-(diethylamino)ethyl ester | C15H22Cl2N2O3 | CID 28056 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Zakonisht limoni dhe hudhra përdoren për të marinuar mishin ose për ti shtuar më shumë shije sallatës.. Duket se njerëzit nuk njohin mjaftueshëm efektet pozitive që këta përbërës i japin shëndetit dhe trupit tonë kur kombinohen së bashku. Ata të dy së bashku bëjnë mrekulli!. Limoni dhe hudhra së bashku përdoren për të ulur nivelin e kolesterolit në gjak, për të zhbllokuar arteriet dhe për të përmirësuar qarkullimin e gjakut, transmeton Klan Kosova.. Jemi shumë më të predispozuar ndaj sulmit në zemër, kur kemi arteriet e bllokuara, ashtu si edhe një mori të sëmundjeve të zemrës.. Industria farmaceutike ofron një mori të produkteve që na ndihmojnë të luftojmë këto sëmundje por ka edhe kura natyrale që e bëjnë një gjë të tillë.. Që të keni qarkullim më të mirë të gjakut, ashtu si edhe një sistem kardiovaskular më të shëndetshëm, shtoni limonin dhe hudhrën në dietën tuaj të përditshme.. Përbërësit:. 1 filxhan lëng të ...
Në anën tjetër, xhenxhefili është i mbushur me antioksidantë të fuqishëm që lehtësojnë problemet e tretjes, zvogëlojnë dhimbjen, pastrojnë arteriet dhe nxisin sistemin imunitar.. Limoni, ndërkohë, balancon nivelet e pH-së, funksionon si detoksifikues për trupin tuaj, si dhe përmirëson shëndetin e lëkurës.. Receta e përgatitjes së pijes:. Përbërësit:. 2l ujë,. 4 limona,. 4 cm rrënjë xhenxhefili,. 4 thelpinj të hudhrës.. Përgatitja:. Limonin, xhenxhefilin dhe hudhrën i lani dhe i prisni në feta të holla.. Që të gjithë përbërësit më pas i fusni në blender, për të arritur një përzierje homogjene.. Hidheni lëngun e fituar në një enë me ujë dhe lëjeni enën në shporet elektrik në nxehtësi mesatare.. Pas pak minutash, largojeni atë nga ngrohësi elektrik dhe lëjeni të ftohet.. Sapo të ftohet, vendoseni në frigorifer. Konsumoni një gotë nga kjo në mëngjes dhe para gjumit.. Falë saj, shëndeti i arterieve do përmirësohet dukshëm, si ...
... may refer to: Naphthols 1-Naphthol 2-Naphthol Benzoxepins 1-Benzoxepin 2-Benzoxepin 3-Benzoxepin Hydroxyazulenes 1- ...
Certain specific substituted 9-N-(1-azabicyclo-[2.2.2.]octan-3-yl)carboxamido-2,3,4,5-tetrahydro-1-benz oxepins and their ...
Benzoxepins/biosynthesis/pharmacology. *Benzyl Compounds/pharmacology. *Carbon Radioisotopes. *Cyclic/biosynthesis/pharmacology ...
C10H8O may refer to: Naphthols 1-Naphthol 2-Naphthol Benzoxepins 1-Benzoxepin 2-Benzoxepin 3-Benzoxepin Hydroxyazulenes 1- ...
... and bromo-1-benzoxepins, the substituent is attached to the aromatic nucleus; its position has not yet been determined. [Sl] J ...
Bohula EA, Scirica BM, Inzucchi SE, McGuire DK, Keech AC, Smith SR, Kanevsky E, Murphy SA, Leiter LA, Dwyer JP, Corbalan R, Hamm C, Kaplan L, Nicolau JC, Ophuis TO, Ray KK, Ruda M, Spinar J, Patel T, Miao W, Perdomo C, Francis B, Dhadda S, Bonaca MP, Ruff CT, Sabatine MS, Wiviott SD. Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial. Lancet. 2018 11 24; 392(10161):2269-2279 ...
Degousee N, Ghomashchi F, Stefanski E, Singer A, Smart BP, Borregaard N, Reithmeier R, Lindsay TF, Lichtenberger C, Reinisch W, Lambeau G, Arm J, Tischfield J, Gelb MH, Rubin BB. Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis. J Biol Chem. 2002 Feb 15; 277(7):5061-73 ...
Full text: Available Index: WPRIM (Western Pacific) Main subject: Benzoxepins / Berberine / Berberine Alkaloids / Drugs, ... Full text: Available Index: WPRIM (Western Pacific) Main subject: Benzoxepins / Berberine / Berberine Alkaloids / Drugs, ... Benzoxepins , Berberine , Berberine Alkaloids , Chromatography, High Pressure Liquid , Drugs, Chinese Herbal , Limonins , ...
Staszewski S, Morales-Ramirez J, Tashima KT, Rachlis A, Skiest D, Stanford J, Stryker R, Johnson P, Labriola DF, Farina D, Manion DJ, Ruiz NM. Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team. N Engl J Med. 1999 Dec 16; 341(25):1865-73 ...
Benzoxepins D3.438.245 D3.633.100.245 Benzoylarginine Nitroanilide D2.92.146.113.200 Benztropine D4.75.80.875.99.722.270 D3.605 ...
Fischer A, Strek ME, Cottin V, Dellaripa PF, Bernstein EJ, Brown KK, Danoff SK, Distler O, Hirani N, Jones KD, Khanna D, Lee JS, Lynch DA, Maher TM, Millar AB, Raghu G, Silver RM, Steen VD, Volkmann ER, Mullan RH, ODwyer DN, Donnelly SC. Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease-Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities. Arthritis Rheumatol. 2019 02; 71(2):182-195 ...
Robichaux JP, Elamin YY, Vijayan RSK, Nilsson MB, Hu L, He J, Zhang F, Pisegna M, Poteete A, Sun H, Li S, Chen T, Han H, Negrao MV, Ahnert JR, Diao L, Wang J, Le X, Meric-Bernstam F, Routbort M, Roeck B, Yang Z, Raymond VM, Lanman RB, Frampton GM, Miller VA, Schrock AB, Albacker LA, Wong KK, Cross JB, Heymach JV. Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity. Cancer Cell. 2019 10 14; 36(4):444-457.e7 ...
Benzoxepins. Chromatography, High Pressure Liquid. Circular Dichroism. Endophytes. Magnetic Resonance Spectroscopy. Molecular ...
Cavallo D, Rudy D, Mohammadi A, Macri J, Adeli K. Studies on degradative mechanisms mediating post-translational fragmentation of apolipoprotein B and the generation of the 70-kDa fragment. J Biol Chem. 1999 Aug 13; 274(33):23135-43 ...
Benzoxepins - isolation & purification , Permeability , Benzoxepins - analysis , Heterocyclic Compounds, 4 or More Rings - ...
BenzoxepinsArylamine N-Acetyltransferase: An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines ... ProcessesNAD+ NucleosidaseDithioniteExcitatory Amino Acid AntagonistsFlavoproteinsCyanidesImidesHemeMeatBenzoxepinsArylamine N- ... ProcessesNAD+ NucleosidaseDithioniteExcitatory Amino Acid AntagonistsFlavoproteinsCyanidesImidesHemeMeatBenzoxepinsArylamine N- ... ProcessesNAD+ NucleosidaseDithioniteExcitatory Amino Acid AntagonistsFlavoproteinsCyanidesImidesHemeMeatBenzoxepinsArylamine N- ...
Benzoxepins , Chemistry , Chromatography, High Pressure Liquid , Methods , Citrus , Chemistry , Discriminant Analysis , ... Benzoxepins , Berberine , Berberine Alkaloids , Chromatography, High Pressure Liquid , Drugs, Chinese Herbal , Limonins , ...
Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection. J Am Soc Nephrol. 2020 11; 31(11):2678-2687 ...
"Synthesis of 2,3-Benzoxepins by Sequential Cyclopropanation / Ring-Enlargement Reactions of Benzopyrylium Triflates with ...
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