AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth Care
BenzopyrenesPolycyclic Hydrocarbons, AromaticPolycyclic CompoundsOccupational ExposureGasolinePyrenesHydrocarbonsBenzo(a)pyrenePregnancyPregnancy ComplicationsPregnancy OutcomeMultilingualismPregnancy, AnimalSmokingLanguageAmitriptylineMuscle Relaxants, CentralSubstance Abuse DetectionHair PreparationsMethenoloneEncyclopedias as TopicInternational AgenciesCarcinogens, EnvironmentalLegislation, DrugCarcinogensChrysenesHydrocarbons, AromaticPhenanthrenesUnited States Occupational Safety and Health AdministrationProtective ClothingHazardous SubstancesRespiratory Protective DevicesNational Institute for Occupational Safety and Health (U.S.)Chemical Hazard ReleaseErythrocytesAnemiaMicronucleus Testso-ChlorobenzylidenemalonitrileErythrocyte MembraneMicronuclei, Chromosome-DefectiveAntimutagenic AgentsThelohaniaInosineDNA-Directed DNA PolymeraseDNA AdductsDNA ReplicationDNA Polymerase III
Benzopyrenes
A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it.
Polycyclic Hydrocarbons, Aromatic
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
Polycyclic Compounds
Compounds consisting of two or more fused ring structures.
Occupational Exposure
The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.
Gasoline
Volative flammable fuel (liquid hydrocarbons) derived from crude petroleum by processes such as distillation reforming, polymerization, etc.
Pyrenes
A group of condensed ring hydrocarbons.
Hydrocarbons
Benzo(a)pyrene
A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Pregnancy Complications
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
Pregnancy Outcome
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
Multilingualism
The ability to speak, read, or write several languages or many languages with some facility. Bilingualism is the most common form. (From Random House Unabridged Dictionary, 2d ed)
Pregnancy, Animal
The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.
Smoking
Inhaling and exhaling the smoke of burning TOBACCO.
Language
A verbal or nonverbal means of communicating ideas or feelings.
Amitriptyline
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Substance Abuse Detection
Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
Hair Preparations
Hair grooming, cleansing and modifying products meant for topical application to hair, usually human. They include sprays, bleaches, dyes, conditioners, rinses, shampoos, nutrient lotions, etc.
Methenolone
A synthetic steroid that has been used for its anabolic action.
Encyclopedias as Topic
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
International Agencies
International organizations which provide health-related or other cooperative services.
Carcinogens, Environmental
Carcinogenic substances that are found in the environment.
Legislation, Drug
Laws concerned with manufacturing, dispensing, and marketing of drugs.
Carcinogens
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
Chrysenes
1,2-Benzphenanthrenes. POLYCYCLIC COMPOUNDS obtained from coal tar.
Hydrocarbons, Aromatic
Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
Phenanthrenes
United States Occupational Safety and Health Administration
An office in the Department of Labor responsible for developing and establishing occupational safety and health standards.
Protective Clothing
Clothing designed to protect the individual against possible exposure to known hazards.
Hazardous Substances
Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.
Respiratory Protective Devices
Respirators to protect individuals from breathing air contaminated with harmful dusts, fogs, fumes, mists, gases, smokes, sprays, or vapors.
National Institute for Occupational Safety and Health (U.S.)
An institute of the CENTERS FOR DISEASE CONTROL AND PREVENTION which is responsible for assuring safe and healthful working conditions and for developing standards of safety and health. Research activities are carried out pertinent to these goals.
Chemical Hazard Release
Uncontrolled release of a chemical from its containment that either threatens to, or does, cause exposure to a chemical hazard. Such an incident may occur accidentally or deliberately.
Erythrocytes
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
Anemia
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
Micronucleus Tests
Induction and quantitative measurement of chromosomal damage leading to the formation of micronuclei (MICRONUCLEI, CHROMOSOME-DEFECTIVE) in cells which have been exposed to genotoxic agents or IONIZING RADIATION.
o-Chlorobenzylidenemalonitrile
A riot control agent which causes temporary irritation of the eyes and the mucosal surface of the respiratory tract. It is a more potent irritant than OMEGA-CHLOROACETOPHENONE, but less incapacitating.
Erythrocyte Membrane
The semi-permeable outer structure of a red blood cell. It is known as a red cell 'ghost' after HEMOLYSIS.
Micronuclei, Chromosome-Defective
Defective nuclei produced during the TELOPHASE of MITOSIS or MEIOSIS by lagging CHROMOSOMES or chromosome fragments derived from spontaneous or experimentally induced chromosomal structural changes.
Antimutagenic Agents
Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved.
Thelohania
A genus of FUNGI, in the family Thelohaniidae, a parasite of red imported fire ants, MOSQUITOES, and other organisms.
Inosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
DNA-Directed DNA Polymerase
DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
DNA Adducts
The products of chemical reactions that result in the addition of extraneous chemical groups to DNA.
DNA Replication
The process by which a DNA molecule is duplicated.
DNA Polymerase III
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7.

The direct spectrophotometric observation of benzo(a)pyrene phenol formation by liver microsomes. (1/611)

Optical spectral repetitive scan analysis during the oxidative metabolism of benzo(a)pyrene by liver microsomal suspensions reveals the time-dependent formation of an intermediate(s) of which the visible spectra resemble those of several benzo(a)pyrene phenols. Liver microsomes from 3-methylcholanthrene-treated rats showed a greater rate of formation of the phenols than did microsomes from control animals; the rate of formation catalyzed by liver microsomes from phenobarbital-pretreated rats was intermediate. When 3-hydroxybenzo(a)pyrene was used as a standard for comparison of activity, the rates of formation of phenols were compared when measured by fluorometric, spectrophotometric, or high-pressure liquid chromatographic analytical techniques. An epoxide hydrase inhibitor, 1,1,1-trichloropropene-2,3-oxide, enhanced phenol formation regardless of the source of liver microsomes, and 7,8-benzoflavone inhibited control and 3-methylcholanthrene-induced microsomal metabolism of benzo(a)pyrene, 7,8-Benzoflavone did not effect benzo(a)pyrene metabolism by liver microsomes from phenobarbital-pretreated rats. The effect of inhibitors on the spectrophotometric assay correlates well with the results obtained from benzo(a)pyrene metabolite analysis using high-pressure liquid chromatography.  (+info)

Differences in benzo(a)pyrene metabolism between rodent liver microsomes and embryonic cells. (2/611)

Differences in benzo(a)pyrene metabolite pattern have been shown by rodent liver microsomes (Sprague-Dawley) and rodent embryo cells from Syrian hamsters and NIH Swiss mice. Rodent liver induced by methylcholanthrene shows marked quantitative variation between species. Additional pattern changes were found in mouse and hamster embryo secondary cultures with a reduction of the K-region metabolites and a marked increase in 9-hydroxybenzo(a)-pyrene. These results are indicative of a region-specific attack on the carcinogen by the cell monooxygenases which is distinct from the liver attack of microsomal enzymes on benzo(a)pyrene. These results suggest that activation and detoxification of benzo(a)pyrene may be species and tissue variable, and susceptibility and resistence to malignant transformation may be predicted on induction of a fortuitous combination of intermediate metabolic steps.  (+info)

Formation in isolated rat liver microsomes and nuclei of benzo(a)pyrene metabolites that bind to DNA. (3/611)

The hepatic nuclear fraction isolated from 3-methylcholanthrene (MC)-treated rats contained enhanced levels of cytochrome P-450 and aryl hydrocarbon hydroxylase [benzo(a)pyrene (BP) monooxygenase], whereas the activities of epoxide hydrase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase and the concentration of cytochrome b5 were not altered. The metabolite pattern of BP was investigated by using high-pressure liquid chromatography and was found to be similar in nuclei and microsomes from MC-treated rats. After incubation of the nuclear fraction with [3H]BP and reduced nicotinamide adenine dinculeotide phosphate, radioactivity was found to be associated with nuclear DNA and the extent of binding was markedly enhanced by pretreatment of the animals with MC. Binding was strongly inhibited by a-napthoflavone but was not influenced by 1,1,1-trichloropropene-2,3-oxide, an inhibitor of epoxide hydrase. In the presence of microsomes from MC-treated rats, increased binding of BP to DNA was observed in nuclei from both control and MC-treated rats; moreover, when the nuclear DNA was replaced by a corresponding amount of calf thymus DNA, the extent of binding was severalfold enhanced. In contrast to nuclei from control rats, the nuclear fraction from MC-treated rats showed an increase in bound radioactivity when incubated with a microsome-free supernatant, obtained by incubating microsomes from MC-treated rats with [3H]BP. The increase in extent of binding was eliminated in the presence of menadione or alpha-naphthoflavone. It is suggested that under the conditions used here the following different processes may have contributed to the total incorporation of BP products into nuclear DNA: (a) formation of DNA-binding products derived from BP by nuclear aryl hydrocarbon hydroxylase; (b) formation of DNA-binding products from microsomal BP metabolites by nuclear aryl hydrocarbon hydroxylase; and (c) direct transfer of reactive microsomal metabolites to nuclear DNA.  (+info)

Nonenzymatic reduction of benzo(a)pyrene diol-epoxides to trihydroxypentahydrobenzo(a)pyrenes by reduced nicotinamide adenine dinucleotide phosphate. (4/611)

The diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene is a potent mutagen and possibly the ultimate carcinogenic form of benzo(a)pyrene. A (7/8,9)-trihydroxy-7,8,9,10,10-pentahydrobenzo(a)pyrene is formed from the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydroxybenzo(a)pyrene by reduction with reduced nicotinamide adenine dinucleotide phosphate. Its formation is linear with reduced nicotinamide adenine dinucleotide phosphate concentration and does not require the presence of enzyme. A (7,9/8)-trihydroxy-7,8,9,10,10-pentahydrobenzo(a)pyrene is similarly formed from the diol-epoxide r-7,t-8-dihydroxy-c-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene by reduction with reduced nicotinamide adenine dinucleotide phosphate. The structures of the trihydroxypentahydrobenzo(a)pyrenes were established by their ultraviolet absorption and mass spectra and their reaction with potassium triacetylosmate.  (+info)

Use of tracheal organ cultures in toxicity testing. (5/611)

Fragments of tracheal epithelium alone or in continuity with connective tissues, can be maintained in culture medium and used for short term or long term studies of toxicity of a variety of chemicals. Large numbers of uniform cultures are prepared with the aid of a slicing device or by application of simple method for dissecting sheets of epithelium free from underlying cartilage. The cultures may be placed in an exposure chamber-incubator mounted on a microscope stage and monitored continually for ciliostasis and exfoliation of cells. Morphology is further studied by fixation of selected specimens and preparation for light microscopy and electron microscopy. Synthetic functions are evaluated by autoradiographic measurement of incorporation of radioactive precursors into macromolecules and other dynamic features are indirectly assessed by histochemical and histoenzymatic methods. Short-term studies using these several techniques have shown that ciliostasis does not correlate with cell injury in all instances, and a long-term study has demonstrated dose dependence of a cytotoxic agent when duration of culture viability is measured. The method lends itself to a broad range of investigations in which dose, period of exposure, and role of cofactors must be independently and quantitatively assessed.  (+info)

Biochemical studies of isolated hamster tracheal epithelium. (6/611)

The epithelial lining of respiratory air passageways is a primary target tissue for toxicity and carcinogenesis in man and in animal models of human disease. The importance of this target tissue was the basis for development of methods to study its biochemistry, and with this information to distinguish the unique properties of this tissue from properties common to all cell types. Biochemical methods employed labeling of macromolecules in isolated hamster treacheas during brief (less than 4 hr) incubation in vitro. Studies of RNA metabolism in isolated tracheas demonstrated a pattern of maturation of ribosomal RNA like that shown for other cell types. Alterations in RNA metabolism were observed in isolated tracheas obtained from vitamin A-deficient hamsters and hamsters previously treated by intratracheal administration of benzo[a]pyrene (BP) plus ferric oxide (Fe2O3) in vivo. Studies with toyocamycin, actinomycin D, and alpha-amanitin, all inhibitors of RNA metabolism, were performed to characterize the class of RNA molecules with a decreased proportion of labeling in tracheas from vitamin A deficient hamsters. In another series of experiments, BP was shown to bind to DNA in epithelial cells of isolated tracheas. The quantity of BP binding was increased by prior intratracheal treatment of hamsters with BP plus Fe2O3 in vivo, this induced binding was inhibited by addition of 7,8-benzoflavone to the incubation medium. Increased BP binding was also observed in isolated tracheas from hamsters believed to be in states of increased susceptibility to respiratory carcinogenesis in vivo. The results show that biochemical studies are feasible with this tissue. Furthermore, a number of questions of importance with regard to this target epithelium are best studied directly in its constituent cells.  (+info)

Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites. (7/611)

The potent carcinogen dibenzo[a,l]pyrene (DB[a,l]P) has been reported to form both stable and depurinating DNA adducts upon activation by cytochrome P450 enzymes and/or cellular peroxidases. Only stable DB[a,l]P-DNA adducts were detected in DNA after reaction of DB[a,I]P-11,12-diol-13,14-epoxides in solution or cells in culture. To determine whether DB[a,l]P can be activated to metabolites that form depurinating adducts in cells with either high peroxidase (human leukemia HL-60 cell line) or cytochrome P450 activity (human mammary carcinoma MCF-7 cell line), cultures were treated with DB[a,l]P for 4 h, and the levels of stable adducts and apurinic (AP) sites in the DNA were determined. DNA samples from DB[a,l]P-treated HL-60 cells contained no detectable levels of either stable adducts or AP sites. MCF-7 cells exposed to 2 microM DB[a,l]P for 4 h contained 4 stable adducts per 10(6) nucleotides, but no detectable increase in AP sites. The results indicate that metabolic activation of DB[a,l]P by cytochrome P450 enzymes to diol epoxides that form stable DNA adducts, rather than one-electron oxidation catalyzed either by cytochrome P450 enzymes or peroxidases to form AP sites, is responsible for the high carcinogenic activity of DB[a,l]P.  (+info)

Pathologic changes induced in respiratory tract mucosa by polycyclic hydrocarbons of differing carcinogenic activity. (8/611)

Seven aromatic polycyclic hydrocarbons (PCHs) were investigated for their toxic effects on respiratory mucosa: benzo(e)pyrene (BeP), pyrene, anthracene, benz(a)anthracene(BaA), dibenz(a,c)anthracene(DBacA), benzo (a)pyrene (BaP), and dimethylbenz(a)anthracene (DMBA). The compounds were chosen because they comprise a spectrum of PCHs ranging from noncarcinogens, to initiators, to weak and strong carcinogens. All of them except DMBA are environmentally relevant chemicals. The chemicals were tested over an 8-week period. Heterotopic tracheal transplants were continously exposed and the histopathologic effects induced by the various PCHs were periodically assessed semiquantitatively. All PCHs exhibited varying degrees of toxicity for respiratory epithelium and submucosa. BeP clearly showed the least toxicity followed by pyrene and anthracene. BaA and DBacA caused marked epithelial and submucosal changes. In addition to epithelial hyperplasia, undifferentiated epithelium and squamous metaplasia developed. Marked mononuclear infiltration occurred in the subepithelial connective tissue. With BaP the epithelial and submucosal changes were similar but were much stronger. DMBA was the most toxic substance, causing epithelial necrosis followed by generalized keratinizing squamous metaplasia; the subepithelial changes consisted of an early acellular exudate and, later (at 8 weeks), marked condensation and hyalinization of the lamina propria. The toxic response pattern of the tracheal mucosa to carcinogenic agents was characterized by the chronicity of epithelial and connective tissue damage, as opposed to the short-lived hyperplastic and inflammatory response elicited by the noncarcinogens and weak initiators.  (+info)

Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo...Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo...
Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides
https://horticulture.oregonstate.edu/biblio/formation-stable-adducts-and-absence-depurinating-dna-adducts-cells-and-dna-treated-potent
IJMS | Free Full-Text | In Vitro Metabolism of Dibenzo[a,l]pyrene, 2-Chlorodibenzo [a,l]pyrene and 10-Chlorodibenzo[a,l]pyrene ...IJMS | Free Full-Text | In Vitro Metabolism of Dibenzo[a,l]pyrene, 2-Chlorodibenzo [a,l]pyrene and 10-Chlorodibenzo[a,l]pyrene ...
Stereoselective metabolism of dibenzo[a,l]pyrene (DB[a,l]P), 2-chlorodibenzo[a,l]pyrene (2-Cl-DB[a,l]P) and 10-chlorodibenzo[a,l]pyrene (10-Cl-DB[a,l]P) by rat liver microsomes was studied and effects of the chloro substituent on the metabolism were determined. All three compounds produced trans-8,9-dihydrodiol, trans-11,12-dihydrodiol, and the 7-hydroxyl derivative as major metabolic products and several other phenolic derivatives as minor metabolites. The trans-8,9- and 11,12-dihydrodiols of DB[a,l]P and 2-Cl-DB[a,l]P preferentially adopted a quasidiequatorial conformation, whereas 10-Cl-DB[a,l]P trans-8,9- and 11,12-dihydrodiols preferentially adopted a quasidiaxial conformation. The yields of the trans-11,12-dihydrodiol metabolites are: DB[a,l]P trans-11,12-dihydrodiol | 2-Cl-DB[a,l]P trans-11,12-dihydrodiol || 10-Cl-DB[a,l]P trans-11,12-dihydrodiol. Circular dichroism (CD) spectral analysis indicates that the trans-8,9-dihydrodiol and trans-11,12-dihydrodiol metabolites from DB[a,l]P, 2-Cl-DB[a,l]P
http://www.mdpi.com/1422-0067/3/9/1008
What is a word ene meaning. Definition of ene.What is a word ene meaning. Definition of ene.
Words Ending In ene: acetylene,achene,advene,agene,akene,alkene,amene,aminobutene,amylene,anadyomene,anthracene,antigene,antivenene,arrasene,azobenzene,bene,benzanthracene,benzene,benzoapyrene,benzopyrene,benzpyrene,buckm
http://words-ending-in-ene.phraseinfo.com/e/
Cliff Pereiras PublicationsCliff Pereiras Publications
Siddens LK, Larin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Lohr CV, Arlt VM, Phillips DH, Williams DE and Baird WM (2012). Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicology and Applied Pharmacology doi: 10.1016/j.taap.2012.08. ...
http://stat.oregonstate.edu/print/109
organic compound | AIVCorganic compound | AIVC
In dwellings and similar spaces with limited volume, dilution of indoor air contaminants may be insufficient. The concentration of contaminants in the inside air depends partly on the rate of emission into the room, partly on the ventilation and the concentration of impurities in the outside air. Sulphur dioxide, hydrocarbons, ozone and lead compounds occur in higher concentrations in the outside air, whereas nitrogen oxides, carbon monoxide, benzpyrene (from tobacco smoke), formaldehyde and dust have higher concentrations indoors. ...
https://www.aivc.org/keywords/organic-compound?page=30
8b,16b-Dihydrodibenzo[g,p]chrysene mixture of cis and trans8b,16b-Dihydrodibenzo[g,p]chrysene mixture of cis and trans
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
http://webbook.nist.gov/cgi/inchi/InChI%3D1S/C26H18/c1-5-13-21-17
ChemIDplus - 70133-84-5 - JZLWANHLFXZFCU-UHFFFAOYSA-N - 2-Chloro-12-(2-piperidinoethyl)dibenzo(d,g)-1,3,6-dioxazocine - Similar...ChemIDplus - 70133-84-5 - JZLWANHLFXZFCU-UHFFFAOYSA-N - 2-Chloro-12-(2-piperidinoethyl)dibenzo(d,g)-1,3,6-dioxazocine - Similar...
70133-84-5 - JZLWANHLFXZFCU-UHFFFAOYSA-N - 2-Chloro-12-(2-piperidinoethyl)dibenzo(d,g)-1,3,6-dioxazocine - Similar structures search, synonyms, formulas, resource links, and other chemical information.
https://chem.nlm.nih.gov/chemidplus/rn/70133-84-5
Lūpų putlintojai ir kaukės - GARBANĖLūpų putlintojai ir kaukės - GARBANĖ
Lūpų kaukės , putlintojai kolagenu, haliuronu, suteikia apimties, apibrėžtumo. Užtikrina ilgalaikį maitinimą, skatina naujų riebalinių ląstelių dalijimasį.
https://garbane.lt/629-lupu-putlintojaikaukes
LPLPO BLANGKO KOSONG - [XLSX Document]LPLPO BLANGKO KOSONG - [XLSX Document]
JAN LAPORAN PEMAKAIAN DAN LEMBAR PERMINTAAN OBAT ( L P L P O ) PUSTU/POLINDES : BULAN : JANUARI PUSKESMAS : JRENGIK TAHUN : 2015 KABUPATEN SAMPANG PROPINSI JAWA TIMUR NOMER…
https://fdokumen.com/document/lplpo-blangko-kosong.html
Molecules | Free Full-Text | Studies on the Interaction Mechanism of Pyrene Derivatives with Human Tumor-Related DNA | HTMLMolecules | Free Full-Text | Studies on the Interaction Mechanism of Pyrene Derivatives with Human Tumor-Related DNA | HTML
Pyrene derivatives can be carcinogenic, teratogenic and mutagenic, thus having the potential to cause malignant diseases. In this work, the interactions of two selected pyrene derivatives (1-OHP and 1-PBO) and human tumor-related DNA (p53 DNA and C-myc DNA) are investigated by spectroscopic and non-native polyacrylamide gel electrophoresis (PAGE) methods. Using fluorescence spectrometry and circular dichroism (CD), DNA interactions of pyrene derivatives are confirmed to occur mainly via the groove binding mode supported by the intercalation into the base pairs of DNA. There is an obvious binding order of pyrene derivatives to the targeted DNA, 1-OHP | 1-PBO. The binding constants of 1-OHP are 1.16 × 106 L×mol−1 and 4.04 × 105 L×mol−1 for p53 DNA and C-myc DNA, respectively, while that of 1-PBO are only 2.04 × 103 L×mol−1 and 1.39 × 103 L×mol−1 for p53 DNA and C-myc DNA, respectively. Besides, the binding of pyrene derivatives to p53 DNA is stronger than that for C-myc DNA. CD and PAGE
http://www.mdpi.com/1420-3049/17/12/14159/htm
Application of pyrene-derived benzimidazole-linked polymers to CO <sub>2</sub> separation under pressure and vacuum swing...Application of pyrene-derived benzimidazole-linked polymers to CO <sub>2</sub> separation under pressure and vacuum swing...
TY - JOUR. T1 - Application of pyrene-derived benzimidazole-linked polymers to CO 2 separation under pressure and vacuum swing adsorption settings. AU - Sekizkardes, Ali Kemal. AU - Islamoǧlu, Timur. AU - Kahveci, Zafer. AU - El-Kaderi, Hani M.. N1 - Copyright: Copyright 2014 Elsevier B.V., All rights reserved.. PY - 2014/8/21. Y1 - 2014/8/21. N2 - Pyrene-derived benzimidazole-linked polymers (BILPs) have been prepared and evaluated for selective CO2 uptake and separation under pressure and vacuum swing conditions. Condensation of 1,3,6,8-tetrakis(4-formylphenyl)pyrene (TFPPy) with 2,3,6,7,10,11-hexaaminotriphenylene, 2,3,6,7,14,15 hexaaminotriptycene, and 3,3′-diaminobenzidine afforded BILP-11, BILP-12 and BILP-13, respectively, in good yields. BILP-12 exhibits the highest specific surface area (SABET = 1497 m2 g-1) among all known BILPs and it also has very high CO2 uptake 5.06 mmol g -1 at 273 K and 1.0 bar. Initial slope selectivity calculations indicate that BILP-11 has high selectivity ...
https://www.scholars.northwestern.edu/en/publications/application-of-pyrene-derived-benzimidazole-linked-polymers-to-co
Binding of isomers of benzo[a]pyrene diol-epoxide to chromatin<...Binding of isomers of benzo[a]pyrene diol-epoxide to chromatin<...
TY - JOUR. T1 - Binding of isomers of benzo[a]pyrene diol-epoxide to chromatin. AU - Kootstra, A.. AU - Slaga, T. J.. PY - 1980/4/14. Y1 - 1980/4/14. N2 - Both the carcinogenic B[a]P diol-epoxide (anti) and its relatively noncarcinogenic isomer, B[a]P diol-epoxide (syn), when reacted with chromatin in vitro, bind more extensively to the internucleosomal region of chromatin than to nucleosomes. These results suggest that the increased binding of B[a]P diol-epoxide (anti) to the internucleosomal region may have little relevance to the process of carcinogenesis.. AB - Both the carcinogenic B[a]P diol-epoxide (anti) and its relatively noncarcinogenic isomer, B[a]P diol-epoxide (syn), when reacted with chromatin in vitro, bind more extensively to the internucleosomal region of chromatin than to nucleosomes. These results suggest that the increased binding of B[a]P diol-epoxide (anti) to the internucleosomal region may have little relevance to the process of carcinogenesis.. UR - ...
https://scholars.uthscsa.edu/en/publications/binding-of-isomers-of-benzoapyrene-diol-epoxide-to-chromatin
Binding of Metabolically Activated Benzo(A)Pyrene to Nuclear Macromolecules<...Binding of Metabolically Activated Benzo(A)Pyrene to Nuclear Macromolecules<...
TY - JOUR. T1 - Binding of Metabolically Activated Benzo(A)Pyrene to Nuclear Macromolecules. AU - Pezzuto, John M.. AU - Lea, Michael A.. AU - Yang, Chung S.. PY - 1976/10. Y1 - 1976/10. N2 - The binding of metabolically activated [3 H]benzo(a)pyrene ([3 H]BP) to the DNA, RNA, histones, and nonhistones of isolated rat liver and lung nuclei was studied. Conditions for optimal binding to the nuclear components were determined. Upon incubation with isolated liver nuclei and reduced nicotinamide adenine dinucleotide phosphate, [3 H]BP was able to bind to nuclear components. The binding appeared to be covalent in nature. Treatment of the rats with 3-methylcholanthrene induced the nuclear aryl hydrocarbon hydroxylase (AHH) activity and also increased the level of carcinogen binding. The addition of rat liver microsomes to the incubation systems greatly enhanced the level of [3 H]BP binding to the macromolecules in the nuclei from both the control and 3-methylcholanthrene-treated rats, and the maximal ...
https://www.researchwithrutgers.com/en/publications/binding-of-metabolically-activated-benzoapyrene-to-nuclear-macrom
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: A potential new model for oral cancer<...Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: A potential new model for oral cancer<...
TY - JOUR. T1 - Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity. T2 - A potential new model for oral cancer. AU - Guttenplan, Joseph B.. AU - Kosinska, Wieslawa. AU - Zhao, Zhong Lin. AU - Chen, Kun Ming. AU - Aliaga, Cesar. AU - Deltondo, Joseph. AU - Cooper, Timothy. AU - Sun, Yuan Wan. AU - Zhang, Shang Min. AU - Jiang, Kun. AU - Bruggeman, Richard. AU - Sharma, Arun K.. AU - Amin, Shantu. AU - Ahn, Kwangmi. AU - El-Bayoumy, Karam. N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.. PY - 2012/6/15. Y1 - 2012/6/15. N2 - Cancer of the oral cavity is a serious disease, affecting about 30,000 individuals in US annually. There are several animal models of oral cancer, but each has certain disadvantages. As a new model, we investigated whether topical application of the tobacco smoke carcinogen, dibenzo[a,l]pyrene (DB[a,l]P) is mutagenic and carcinogenic in the oral cavity of the B6C3F1 lacI and B6C3F1 mouse, respectively. B6C3F1 lacI mice ...
https://nyuscholars.nyu.edu/en/publications/mutagenesis-and-carcinogenesis-induced-by-dibenzoalpyrene-in-the-
Plus itPlus it
When [3H]benzo[a]pyrene is incubated in vitro together with deproteinized salmon sperm DNA, NADPH, and mouse liver microsomes, the covalent binding of benzo[a]pyrene metabolites to DNA occurs. The metabolite-nucleoside complexes can be resolved into at least nine distinct peaks by elution of a Sephadex LH-20 column with a water-methanol gradient. These peaks are arbitrarily designated A (most polar) through I (least polar). With the use of synthetic and biologically produced metabolites, seven of nine peaks are tentatively assigned to one or more metabolites of benzo[a]pyrene. Peaks A and C are unidentified. Peaks B, D, F, and I include products of benzo[a]pyrene quinones that are further metabolized. Peak E reflects almost exclusively both the cis- and trans-7,8-diol 9,10-epoxides of benzo[a]pyrene. Peak G represents predominantly the K-region metabolite (the 4,5-oxide), interacting with one or more nucleosides. Peak H comprises reactive intermediates resulting from the further metabolism of ...
http://molpharm.aspetjournals.org/content/14/2/306
Mechanism of benzo[a]pyrene-induced Cyp1a-1 gene expression in mouse Hepa 1c1c7 cells: Role of the nuclear 6 s and 4 s proteins...Mechanism of benzo[a]pyrene-induced Cyp1a-1 gene expression in mouse Hepa 1c1c7 cells: Role of the nuclear 6 s and 4 s proteins...
TY - JOUR. T1 - Mechanism of benzo[a]pyrene-induced Cyp1a-1 gene expression in mouse Hepa 1c1c7 cells. T2 - Role of the nuclear 6 s and 4 s proteins. AU - Merchant, M.. AU - Wang, X.. AU - Kamps, C.. AU - Rosengren, R.. AU - Morrison, V.. AU - Safe, S.. PY - 1992/1. Y1 - 1992/1. N2 - Treatment of wild-type (wt) aryl hydrocarbon (Ah)-responsive mouse Hepa 1c1c7 cells with benzo[a]pyrene (B[a]P) caused a concentration-dependent induction of ethoxyresorufin O-deethylase (EROD) activity. In contrast, B[a]P was inactive as an inducer in Ah nonresponsive class 1 and class 2 mutant cell lines. In parallel experiments, the nuclear fractions from wt cells treated with 10-7 m [3H]B[a]P contained both the 4 s carcinogen binding protein and the 6 s (Ah receptor) complexes, whereas only the 4 s complex was present in the nuclear fraction of the class 2 mutant cells. The results obtained from cotreatment of wt Hepa 1c1c7 cells with 10-6 or 10-7 m B[a]P and 5 × 10-7 or 10-7 m ...
https://scholars.houstonmethodist.org/en/publications/mechanism-of-benzoapyrene-induced-cyp1a-1-gene-expression-in-mous
Roberts Stochastic thoughts: 4/1/08 - 5/1/08Roberts Stochastic thoughts: 4/1/08 - 5/1/08
Butylated hydroxyanisole (BHA) is a commonly used food additive with demonstrated inhibitory action against chemical carcinogenesis in animals. In order to elucidate the mechanism of the anticarcinogenic action, the effects of BHA on benzo(a)pyrene (BP) metabolism were studied with lung microsomes from female mice. BHA treatment (0.5% in the diet for 7 days) inhibited BP metabolism and altered the ratios among different metabolites as analyzed by high-performance liquid chromatography. The treatment reduced the metabolic formation of 9,10-dihydroxy-9,10-dihydrobenzo(a)pyrene, but not the production of 3-hydroxybenzo(a)pyrene and trans-4,5-dihydroxy-4,5-dihydrobenzo(a)pyrene. Since the gross microsomal cytochrome P-450 content was not significantly affected by the treatment, the change of regioselectivity in BP metabolism was probably due to the alteration of cytochrome P-450 isozyme composition by dietary BHA. General and regioselective inhibition of BP metabolism was also observed when BHA was ...
http://rjwaldmann.blogspot.com/2008_04_01_archive.html
Advertisement In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon...Advertisement In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon...
Advertisement In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon Receptor
https://bee.oregonstate.edu/biblio/advertisement-utero-exposure-mice-dibenzoalpyrene-produces-lymphoma-offspring-role-aryl
Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse s by W Levin, A W. Wood et al.Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse s by W Levin, A W. Wood et al.
Levin, W; Wood, A W.; Wislocki, P G.; Kapitulnik, J; Yagi, H; Jerina, D M.; and Conney, A H., Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse skin. (1977). Subject Strain Bibliography 1977. 715 ...
https://mouseion.jax.org/ssbb1977/715/
Enzyme immunoassay of benzo[a]pyrene conjugated to DNA, RNA and microsomal proteins using a monoclonal antibody. - Semantic...Enzyme immunoassay of benzo[a]pyrene conjugated to DNA, RNA and microsomal proteins using a monoclonal antibody. - Semantic...
An enzyme immunoassay for the detection of benzo[a]pyrene covalently conjugated to macromolecules has been developed. The monoclonal antibody, raised through in vitro immunization reacted with benzo[a]pyrene metabolites bound to DNA, RNA and proteins. The lower detection limit for the assay was 1 pmol for benzo[a]pyrene bound to DNA or RNA, and 5 pmol when bound to protein.
https://www.semanticscholar.org/paper/Enzyme-immunoassay-of-benzo-a-pyrene-conjugated-to-Wallin-Borrebaeck/9877edcc0bbb0a62e3aa44ba46aab97c2e32a42f
192-97-2, benzo[e]pyrene, CAS No 192-97-2 benzo[e]pyrene nl192-97-2, benzo[e]pyrene, CAS No 192-97-2 benzo[e]pyrene nl
CAS NO:192-97-2; Chemical name:benzo[e]pyrene ; physical and chemical property of 192-97-2, benzo[e]pyrene is provided by ChemNet.com
http://www.chemnet.com/cas/nl/192-97-2/benzo%5Be%5Dpyrene.html
Benzo[e]pyrene | CAS: 192-97-2 | Benzo[e]pyrene SupplierBenzo[e]pyrene | CAS: 192-97-2 | Benzo[e]pyrene Supplier
Clinivex is a high quality reference standard supplier of Benzo[e]pyrene, CAS no - 192-97-2. View more information regarding Benzo[e]pyrene, including solubility, MSDS & more.
https://theclinivex.com/benzo-e-pyrene.html
History Interleukin-8 (IL-8) features as a significant chemoattractant and has pivotal | Epigenetic regulation of CpG promoter...History Interleukin-8 (IL-8) features as a significant chemoattractant and has pivotal | Epigenetic regulation of CpG promoter...
History Interleukin-8 (IL-8) features as a significant chemoattractant and has pivotal jobs in the initiation and advancement of chronic obstructive pulmonary disease TMC 278 (COPD) and cigarette smoke cigarettes is a most risk aspect contributing to the introduction of COPD. cells was dependant on cell counting package-8 package luciferase activity was measured in reporter gene-expressing 16HEnd up being cells and IL-8 amounts in lifestyle supernatants had been quantified by enzyme-linked immunosorbent assay. Outcomes On the nontoxic dosages chemical substances owned by nicotine aromatic amines benzopyrene phenols aldehydes plus some various other volatile organics dose-dependently elevated reporter gene appearance. Consistently the TMC 278 consultant compounds belonging to nicotine aromatic amines benzopyrene phenols aldehydes and some other volatile organics significantly and dose-dependently increased IL-8 levels in TMC 278 the culture supernatants of 16HBE cells among these compounds ...
http://elegantindulgence.net/history-interleukin-8-il-8-features-as-a-significant-chemoattractant-and-has-pivotal/
4.E: Mutation and Variation (Exercises) - Biology LibreTexts4.E: Mutation and Variation (Exercises) - Biology LibreTexts
4.1 Polymorphisms and mutations are both variations in DNA sequence and can arise through the same mechanisms. We use the term polymorphism to refer to DNA variants that are relatively common in populations. Mutations affect the phenotype.. 4.2 Misreading of bases during replication can lead to substitution and can be caused by things like tautomerism, DNA alkylating agents, and irradiation.. 4.3 Looping out of DNA on the template strand during replication; strand breakage, due to radiation and other mutagens; and (discussed in earlier chapters) chromosomal aberrations such as deletions and translocations.. 4.4 Looping out of DNA on the growing strand during replication; transposition; and (discussed in earlier chapters) chromosomal aberrations such as duplications, insertions, and translocation.. 4.5 Benzopyrene is one of many hazardous compounds present in smoke. Benzopyrene is an intercalating agent, which slides between the bases of the DNA molecule, distorting the shape of the double helix, ...
https://bio.libretexts.org/TextMaps/Map%3A_Online_Open_Genetics_
PQR | 9-(2-deoxy-5-o-phosphonopentofuranosyl)-n-(7,8,9-trihydroxy-7,8,9,10-tetrahydrobenzo[pqr]tetraphen-10-yl)-9h-purin-6-aminePQR | 9-(2-deoxy-5-o-phosphonopentofuranosyl)-n-(7,8,9-trihydroxy-7,8,9,10-tetrahydrobenzo[pqr]tetraphen-10-yl)-9h-purin-6-amine
You are viewing an interactive 3D depiction of the molecule 9-(2-deoxy-5-o-phosphonopentofuranosyl)-n-(7,8,9-trihydroxy-7,8,9,10-tetrahydrobenzo[pqr]tetraphen-10-yl)-9h-purin-6-amine (C30H14N5O9P) from the PQR.
http://pqr.pitt.edu/mol/PCKWPNBFFBGKTM-HGCLXHPZSA-N
DIBENZO[A,E]PYRENE UNLABELED - Creative ProteomicsDIBENZO[A,E]PYRENE UNLABELED - Creative Proteomics
Creative-Proteomics offer cas 192-65-4 DIBENZO[A,E]PYRENE UNLABELED. We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
https://www.creative-proteomics.com/product/detail-cpil100262_33602.htm
Influence of combined deficiency of fat and vitamin A on benzo(a)pyrene-induced lung carcinogenesis in rats. - Semantic ScholarInfluence of combined deficiency of fat and vitamin A on benzo(a)pyrene-induced lung carcinogenesis in rats. - Semantic Scholar
The present study shows the effect of combined dietary deprivation of fat and vitamin A on benzo(a)pyrene (BaP) induced lung carcinogenesis in male Wistar rats. Lung tumors were induced by intratracheal instillation of BaP-Fe2O3 in normal saline. The tumor incidence and tumor burden in control animals were 82% and 2.28 respectively. Fat deficiency decreased the tumor incidence to 57% and tumor burden to 1.66. On the other hand, in vitamin A deficiency these were 83% and 4.02 respectively. Fat deprivation in the diet of animals fed with vitamin A deficient diet decreased the tumor incidence and tumor burden to 69.6% and 2.7 respectively. The results suggest a protective role of low intake of fat in vitamin A deficiency for BaP-induced lung tumorigenesis in rats.
https://www.semanticscholar.org/paper/Influence-of-combined-deficiency-of-fat-and-vitami-Khanduja-Koul/c49dc9c96336c7dffc33186aba56f04d5033fb93
Formation of glucuronide, sulphate and glutathione conjugates of benzo by J Zaleski, S K. Bansal et al.Formation of glucuronide, sulphate and glutathione conjugates of benzo by J Zaleski, S K. Bansal et al.
Zaleski, J; Bansal, S K.; and Gessner, T, Formation of glucuronide, sulphate and glutathione conjugates of benzo[a]pyrene metabolites in hepatocytes isolated from inbred strains of mice. (1983). Subject Strain Bibliography 1983. 1888 ...
https://mouseion.jax.org/ssbb1983/1888/
Dibenzo[b,e]Thiepin-11(6H)-One 1531-77-7 MSDS, Safety Technical Specifications MSDSDibenzo[b,e]Thiepin-11(6H)-One 1531-77-7 MSDS, Safety Technical Specifications MSDS
Dibenzo[b,e]Thiepin-11(6H)-One 1531-77-7 MSDS report, Dibenzo[b,e]Thiepin-11(6H)-One MSDS safety technical specifications search, Dibenzo[b,e]Thiepin-11(6H)-One safety information specifications ect.
http://www.molbase.com/en/msds_1531-77-7-moldata-63963.html
6-methoxy-1,5-dihydrobenzo[cd]indol-4(3H)-one | C12H11NO2 - ChemSynthesis6-methoxy-1,5-dihydrobenzo[cd]indol-4(3H)-one | C12H11NO2 - ChemSynthesis
6-methoxy-1,5-dihydrobenzo[cd]indol-4(3H)-one - chemical structural formula, chemical names, chemical properties, synthesis references
http://www.chemsynthesis.com/base/chemical-structure-14805.html
Phenylethynyl-pyrene (PEP) in FluorophoresPhenylethynyl-pyrene (PEP) in Fluorophores
Phenylethynylpyrene (PEP) is a pyrene derivative with red-shifted absorption and emission spectra. Fits blue channel of qPCR instruments, can be used for multiplex experiments.
https://www.lumiprobe.com/t/fluorophores/phenylethynyl-pyrene
Trichloroepoxypropane Summary Report | CureHunterTrichloroepoxypropane Summary Report | CureHunter
Trichloroepoxypropane: A potent epoxide hydrase and aryl hydrocarbon hydroxylase inhibitor. It enhances the tumor-initiating ability of certain carcinogens.
http://www.curehunter.com/public/keywordSummaryD014239-Trichloroepoxypropane.do
dibenzo[b,d]furan-2-carbaldehyde | C13H8O2 - PubChemdibenzo[b,d]furan-2-carbaldehyde | C13H8O2 - PubChem
dibenzo[b,d]furan-2-carbaldehyde | C13H8O2 | CID 220843 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Dibenzofurancarboxaldehyde
A sz raz b r pol sa l p sr l l p sre - H ziPatikaA sz raz b r pol sa l p sr l l p sre - H ziPatika
Sokan m r az els l p sn l, a tiszt t sn l elrontj k a sz raz b r pol s t. De akad, aki mindent helyesen csin l, a sminkkel azonban t nkreteszi a b r pol si rutinja j t kony hat s t.
https://www.hazipatika.com/eletmod/tudomanyos_borapolas/cikkek/a_szaraz_bor_apolasa_lepesrol_lepesre/20201007090130
1GXB | Genus1GXB | Genus
chains in the Genus database with same CATH superfamily 4YYY A; 5C7S A; 1ZYK A; 1V8G A; 5BO3 A; 2ELC A; 4ZOK A; 4LHM A; 4N8Q A; 3QQS A; 4X5D A; 4M0R A; 4X5E A; 1UOU A; 3QSA A; 4N5V A; 4ZOF A; 1ZXY A; 3GBR A; 1OTP A; 3TWP A; 4OWN A; 4MUO A; 3R88 A; 4X46 A; 4X59 A; 1AZY A; 1KHD A; 4GIU A; 4OWU A; 1GXB A; 4OWM A; 3R6C A; 3UU1 A; 1VQU A; 4YEK A; 4OWV A; 4IJ1 A; 4GKM A; 3H5Q A; 4GA4 A; 4X58 A; 4X5C A; 5C1R A; 2WK5 A; 1O17 A; 4EAD A; 2J0F A; 4XR5 A; 2GVQ A; 5BYT A; 4EAF A; 4OWO A; 4HKM A; 5EP8 A; 3QR9 A; 4X5A A; 4N93 A; 4ZOJ A; 2DSJ A; 1ZVW A; 4GTN A; 2TPT A; 4GA6 A; 4X5B A; 4ZTV A; 5EY3 A; 1KGZ A; 3QS8 A; 2BPQ A; 5C2L A; 4OWS A; 2WK6 A; 5BNE A; 4GA5 A; 4OWQ A; 1BRW A; 4YI7 A; 5BO2 A; #chains in the Genus database with same CATH topology 4YYY A; 5C7S A; 1ZYK A; 1V8G A; 5BO3 A; 2ELC A; 4ZOK A; 4LHM A; 4N8Q A; 3QQS A; 4X5D A; 4M0R A; 4X5E A; 1UOU A; 1RF8 B; 3QSA A; 4N5V A; 4ZOF A; 1ZXY A; 3GBR A; 1OTP A; 3TWP A; 4OWN A; 4MUO A; 3R88 A; 4X46 A; 4X59 A; 1AZY A; 1KHD A; 4GIU A; 4OWU A; 1GXB A; 4OWM A; 3R6C ...
https://genus.fuw.edu.pl/view/1GXB/A/
Zelen j l - p rodn prost edek pro zdrav a kr su - P rodn kosmetika LadyBioZelen j l - p rodn prost edek pro zdrav a kr su - P rodn kosmetika LadyBio
Zelen j l - p rodn prost edek pro zdrav a kr su - J l je jednou z nejstar ch surovin, kter lov k za al vyu vat. A v kosmetice? - Redakce
https://m.ladybio.cz/clanky-zeleny-jil-prirodni-prostredek-pro-zdravi-a-krasu.html
234Parts - Used Steering Rack for Mercedes Benz C300 2008 - 2011, E250 2014, E300 2012 - 2013, E350 2010 - 2014, E550 2010 -...234Parts - Used Steering Rack for Mercedes Benz C300 2008 - 2011, E250 2014, E300 2012 - 2013, E350 2010 - 2014, E550 2010 -...
Used Steering Rack for Mercedes Benz C300 2008 - 2011, E250 2014, E300 2012 - 2013, E350 2010 - 2014, E550 2010 - 2014, E63 AMG 2014, E63 AMG S 2014, GL320 2007 - 2009, GL350 2010 - 2012, GL450 2007 - 2012, GL550 2010 - 2011, ML320 2002 - 2009, ML350 2003 - 2011, ML450 2010 - 2011, ML500 2006 - 2007, ML550 2008 - 2011, ML63 AMG 2007 - 2010 - a wide range of high-quality Steering Rack spare parts online
https://234parts.com/auto-parts/steering/steering-rack/clean-front-shock-absorber-16
Vxdiag Benz C6 | forobd2tool.comVxdiag Benz C6 | forobd2tool.com
Question: I have a Vxdiag Benz C6 device and Im hoping to do some coding of my Mercedes A-Class W176 2015. Do I need to enable […]. ...
http://forobd2tool.com/blog/tag/vxdiag-benz-c6/
Karaci er Absesi TedaviKaraci er Absesi Tedavi
E er karaci er absesi bakteriden kaynaklan yorsa, doktor ak t l p temizlenmesi i in kateterizasyon ve be hafta damardan antibiyotik verilmesini nerebilir. Bazen cerrahi m dahal
http://www.tedavin.com/sindirim-sistemi/499-karaciger-absesi-tedavi.html
Induction of Aryl Hydrocarbon Hydroxylase in Ambystoma tigrinum - Digital LibraryInduction of Aryl Hydrocarbon Hydroxylase in Ambystoma tigrinum - Digital Library
Aryl hydrocarbon hydroxylase (AHH) was induced 15-fold in Ambystoma tigrinum by intraperitoneal injection of 3-methylcholanthrene in corn oil, or 10-fold by addition of aromatic polycyclic hydrocarbons to the aqueous environment of the neotene animal. The cytochrome P-450-associated microsomal enzyme is similar to the inducible, one-gene, autosomal-dominant system typical in the laboratory mouse and man. Differences in optimal temperature for enzyme induction and activity were noted in organ culture of human and Ambystoma tissues, and ratios of benzpyrene metabolites differed between Ambystoma and Mus. The half life of enzyme activity induced in vivo was related to the excretion of hydrocarbon metabolites.
https://digital.library.unt.edu/ark:/67531/metadc663117/
NIOSHTIC-2 Publications Search - 00163633 - Effects of organic solvent vehicles on benzo[a]pyrene metabolism in rabbit lung...NIOSHTIC-2 Publications Search - 00163633 - Effects of organic solvent vehicles on benzo[a]pyrene metabolism in rabbit lung...
Effects of five organic solvent vehicles on benzo(a)pyrene- hydroxylase (BP-hydroxylase) activity and on the benzo(a)pyrene (50328) (BP) metabolite profile were studied in lung microsomes prepared from male New Zealand white rabbits. The production of 3- OH-benzo(a)pyrene (13345216) and 9-OH-benzo(a)pyrene (17573216) was used to evaluate the effects of dimethyl-sulfoxide (DMSO), acetone, methanol,
https://www.cdc.gov/niosh/nioshtic-2/00163633.html
Plus itPlus it
Two diol-epoxide metabolites of benzo[c]phenanthrene and benzo[a]pyrene, polynuclear aromatic hydrocarbons which occur in the environment, were tested for carcinogenicity by direct injection into the mammary fat pads of female CD rats. The compounds anti-3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene (BcPDE), a fjord region diol-epoxide, and anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, a bay region diol-epoxide, were applied at total doses of 12.2 µmol. 6-Nitrochrysene was applied at the same dose as a positive control (K. El-Bayoumy, A. Rivenson, P. Upadhyaya, Y-H. Chae, and S. S. Hecht, Cancer Res. 53: 3719-3722, 1993). The sterically hindered fjord region diol-epoxide BcPDE was a powerful mammary tumorigen and carcinogen, rapidly inducing significantly more fibroadenoma and adenocarcinoma than either of the other compounds. Anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene was a weaker mammary tumorigen than BcPDE and 6-nitrochrysene. The ...
http://cancerres.aacrjournals.org/content/54/1/21
Biblio | Page 4 | College of Agricultural Sciences | Oregon State UniversityBiblio | Page 4 | College of Agricultural Sciences | Oregon State University
V. J. Melendez-Colon, Smith, C. Allen, Seidel, A., Luch, A., Platt, K. L., and Baird, W. M., Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides, Proceedings of the National Academy of Sciences, vol. 94, pp. 13542-13547, 1997. ...
https://bee.oregonstate.edu/biblio?page=3&%3Bf%5Bauthor%5D=4291&f%5Bauthor%5D=681
Biblio | Page 5 | College of Agricultural Sciences | Oregon State UniversityBiblio | Page 5 | College of Agricultural Sciences | Oregon State University
V. J. Melendez-Colon, Smith, C. Allen, Seidel, A., Luch, A., Platt, K. L., and Baird, W. M., Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides, Proceedings of the National Academy of Sciences, vol. 94, pp. 13542-13547, 1997. ...
https://agsci.oregonstate.edu/biblio?page=4&f%5Bauthor%5D=716&s=year&o=asc
Biblio | Page 6 | College of Agricultural Sciences | Oregon State UniversityBiblio | Page 6 | College of Agricultural Sciences | Oregon State University
V. J. Melendez-Colon, Smith, C. Allen, Seidel, A., Luch, A., Platt, K. L., and Baird, W. M., Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides, Proceedings of the National Academy of Sciences, vol. 94, pp. 13542-13547, 1997. ...
https://emt.oregonstate.edu/biblio?page=5&f%5Bauthor%5D=691&s=year&o=desc
6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one Summary Report | CureHunter6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one Summary Report | CureHunter
6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one: inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase
http://www.curehunter.com/public/keywordSummaryC438505-6-8-diallyl-5-7-dihydroxy-2--2-allyl-3-hydroxy-4-methoxyphenyl-1-H-benzo-b-pyran-4-one.do
ChemIDplus - 136623-01-3 - SCDBMLHUXJBJSS-UHFFFAOYSA-N - 5-Nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime - Similar...ChemIDplus - 136623-01-3 - SCDBMLHUXJBJSS-UHFFFAOYSA-N - 5-Nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime - Similar...
136623-01-3 - SCDBMLHUXJBJSS-UHFFFAOYSA-N - 5-Nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime - Similar structures search, synonyms, formulas, resource links, and other chemical information.
https://chem.nlm.nih.gov/chemidplus/rn/136623-01-3
DSpace at EWHA: 1H-Benzo[f]indole-4,9-dione 과 1H-pyrrolo[3,2-g]quinoline-4,9-dione 합성 및 항진균 작용 연구DSpace at EWHA: 1H-Benzo[f]indole-4,9-dione 과 1H-pyrrolo[3,2-g]quinoline-4,9-dione 합성 및 항진균 작용 연구
Quinone 유도체들은 항진균, 항암, 항균, 항말라리아 등 다양한 생리활성을 나타낸다. 본 연구에서는 quinone 유도체 중 우수한 생리활성이 예상되는 quinone 유도체를 합성하여 항진균 작용 및 그 생리활성을 검색하였다. 1,4-Naphthoquinone을 ZnCl2를 촉매로 하여 ethyl benzoylacetate와 aryl thiol과 반응시켜 ethyl 5-oxo-2-phenyl-4-(phenylthio)-5,9b-dihydronaphtho[1,2-b]furan-3-carboxylate (NQMSs) 유도체 2개를 합성하였다. 2,3-Dichloro-5-hydroxynaphthalene-1,4-dione은 5-hydroxynaphthalene-1,4-dione를 Cl2 gas 와 반응시켜 합성하였고, 다양한 pyridine derivatives와 active methylene derivatives와 반응시켜 10-hydroxybenzo[f]pyrido[1,2-a]indole-6,11-dione (JQPMs) 유도체 9개를 합성하였다. 또 2,3-dichloro-5-hydroxynaphthalene-1,4-dione과 ethyl cyanoacetate를 반응시키고 다양한 arylamine을 반응시켜 ethyl ...
http://dspace.ewha.ac.kr/handle/2015.oak/213537
OPUS Würzburg | SearchOPUS Würzburg | Search
The lnfluence of mlcrosomal and nuclear aryl hydrocarbon hydroxylase (AHH) actlvlty on the covalent blndlng of [G·3H]benzo(a )pyrene to rat llver DNA was evaluated in viWJ. lnductlon of mlcrosomal AHH was obtalned alter phenobarbltal treatment (160% of control), whlch also lncreased DNA blndlng to 190%, but left the nuclear actlvlty unchanged. Nuclear AHH was lnduced wlth dleldrln (150%), and the blndlng was decreased to 75%, whereaa the mlcrosomal AHH was at control Ievei. The lncreaslng effect of mlcrosomal AHH lnductlon as weil as the decreaslng effect of nuclear AHH lnductlon on the blndlng was shown clearly when the data of the Individual rata were uaed to solve the equatlon Binding = e•(mlcroeomal AHH) + b•(nuclear AHH) + c Multiple linear regresslon analysls wlth the data from 10 anlmala reaulted ln positive valuea for a and c, a negative value for b, and a good multiple correlatlon coefflclent of r = 0.974. Pretreatment wlth 3-methylcholanthrene ln· duced mlcrosomal AHH to 380% of ...
https://opus.bibliothek.uni-wuerzburg.de/solrsearch/index/search/searchtype/all/rows/10/facetNumber_author_facet/all/institutefq/Institut+f%C3%BCr+Pharmakologie+und+Toxikologie/start/0/sortfield/year/sortorder/asc
ACRCF | ScientistsACRCF | Scientists
Chapel Hill, NC 27599-7525. Cells are particularly vulnerable to the cancer causing effects of chemicals if the treatments occur when the cells start to synthesize DNA during the cell growth cycle. Studies are probing the mechanisms that cause this susceptibility including identifying genomic sites replicated early in the DNA synthesis phase. A separate area of study concerns the development of endometrial cancer. Human endometrium has been reconstructed in culture from its constituent cells and interactions between endometrial epithelial and stromal cells determine normal tissue structure and function. The reconstructed endometrium has been used to reproduce progressive steps of endometrial cancer development in translational studies.. Previous studies showed that cells are most susceptible to malignant transformation when they are treated with chemical carcinogens during the earliest part of the S phase. DNA is also preferentially damaged when it replicates, with elevated carcinogen binding to ...
http://acrcf.org/research/scientists/
Benzo(a)pyrene-7,8-diol, 6-fluoro-7,8-dihydro- | C20H13FO2 - PubChemBenzo(a)pyrene-7,8-diol, 6-fluoro-7,8-dihydro- | C20H13FO2 - PubChem
Benzo(a)pyrene-7,8-diol, 6-fluoro-7,8-dihydro- | C20H13FO2 | CID 128565 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/128565
China CAS NO.1609080-03-6 N-(m-tolyl)dibenzo[b,d]furan-4-amine Suppliers and Factory - Daken Chemical LimitedChina CAS NO.1609080-03-6 N-(m-tolyl)dibenzo[b,d]furan-4-amine Suppliers and Factory - Daken Chemical Limited
Daken Chemical Limited: Professional CAS NO.1609080-03-6 N-(m-tolyl)dibenzo[b,d]furan-4-amine suppliers in China. If youre going to buy or wholesale bulk OLED Intermediates at affordable price, welcome to get quotation from our factory.
http://m.dakentech.com/electronic-chemicals/oled-intermediates/n-m-tolyl-dibenzo-b-d-furan-4-amine-cas-no.html
RCSB PDB - 1JDG: Solution Structure of a Trans-Opened (10S)-dA Adduct of (+)-(7S,8R,9S,10R)-7,8-Dihydroxy-9,10-epoxy...RCSB PDB - 1JDG: Solution Structure of a Trans-Opened (10S)-dA Adduct of (+)-(7S,8R,9S,10R)-7,8-Dihydroxy-9,10-epoxy...
1JDG: Solution structure of a trans-opened (10S)-dA adduct of (+)-(7S,8R,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a fully complementary DNA duplex: evidence for a major syn conformation.
http://www.rcsb.org/pdb/explore/explore.do?structureId=1JDG
Search results | TNO PublicationsSearch results | TNO Publications
To study the possible reduction by eugenol of the mutagenicity and genotoxicity of benzoja]pyrene (B[a]P) in vivo, the X-lacZ-transgenic mouse strain 40.6 (Muta(TM)Mouse) was used. Male mice were fed a diet containing 0.4% (w/w) eugenol or a control diet for 58 days. On day 10, half of the mice received an i.p. dose of 100 mg/kg b.w. B[a]P. The ...
https://repository.tno.nl/islandora/search/subject%3A%22Animals%22?f%5B0%5D=mods_subject_topic_ss%3A%22Liver%22&f%5B1%5D=mods_name_personal_author_namePart_family_ss%3A%22van%5C%20Delft%22
Molcan :: Product DetailsMolcan :: Product Details
Quetiapine EP Impurity C ;. 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl 2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)acetate ;. CAS # 1798840-31-9 ;. C40H42N6O3S2 ;. MW: 718.93. ...
http://molcan.com/products/3271
14,14,15,15-tetradehydro-7,7-spirobi[dibenzo... - Registration Dossier - ECHA14,14,15,15-tetradehydro-7,7-spirobi[dibenzo... - Registration Dossier - ECHA
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
https://echa.europa.eu/registration-dossier/-/registered-dossier/6054/4/6
High-pressure liquid chromatography (HPLC) is a m... - OpenStudyHigh-pressure liquid chromatography (HPLC) is a m... - OpenStudy
High-pressure liquid chromatography (HPLC) is a method used in chemistry and biochemistry to purify chemical substances. The pressures used in this p...
http://openstudy.com/updates/4f7b3c20e4b0884e12ab0eba
Lannett Co Inc (LCI) Holdings Cut by First Quadrant L P CA - Watch List NewsLannett Co Inc (LCI) Holdings Cut by First Quadrant L P CA - Watch List News
First Quadrant L P CA cut its holdings in Lannett Co Inc (NYSE:LCI) by 23.8% during the 3rd quarter, according to the company in its most recent disclosure with the SEC. The firm owned 15,400 shares of the companys stock after selling 4,800 shares during the quarter. First Quadrant L P CAs holdings in Lannett […]
https://www.watchlistnews.com/lannett-co-inc-lci-holdings-cut-by-first-quadrant-l-p-ca/1685139.html
FORMERON FAQ - AnabolicMinds.com - Page 14FORMERON FAQ - AnabolicMinds.com - Page 14
Brundel, dang, I dont like hearing that about 7, 8 benzoflavone . I was about to pick up several bottles of Dermacrine when they were back in stock.
http://anabolicminds.com/forum/black-lion-research/209597-formeron-faq-14.html
Officiella säkerhetsbetyg för Mercedes Benz C Class 2009Officiella säkerhetsbetyg för Mercedes Benz C Class 2009
Upptäck Euro NCAP:s Mercedes Benz C Class 2009 säkerhetsbedömning: detaljerade resultat, bilder, video och kommentarer till krocktest
https://www.euroncap.com/sv/results/mercedes-benz/c-class/11050
ایمنی‏زایی ناحیه‏ای اسیدهای آمینة 7601 تا 8140 از پروتئین Bap اسینتوباکتر بومانیایمنی‏زایی ناحیه‏ای اسیدهای آمینة 7601 تا 8140 از پروتئین Bap اسینتوباکتر بومانی
هدف: اسینتوباکتر بومانی یکی از پاتوژن‏های اصلی بیمارستانی است و ظرفیت بالایی برای مقاومت به انواع مواد ضد میکروبی موجود دارد. اسینتوباکتر بومانی انواع متفاوتی از عفونت‏ها شامل پنومونی، مننژیت و عفونت‏های مرتبط با خون را ایجاد می‏کند. پروتئین‏های مربوط به بیوفیلم (Bap) پروتئینی اختصاصی در سطح سلول است که مستقیماً در تشکیل بیوفیلم در اسینتوباکتر بومانی مورد نیاز است و نقش اصلی را در عفونت‏زایی باکتری بازی می‏کند. در مطالعه قبلی محققان حاضر نواحی متعددی از این پروتئین بررسی شد و با در نظر گرفتن معیارهای مختلف، چند ناحیه به عنوان نواحی حفاظت شده و ایمنی
http://mjms.modares.ac.ir/article_10451.html
Benzo(a)pyreneBenzo(a)pyrene
"Benzopyrene and Vitamin A deficiency". Researcher links cigarettes, vitamin A and emphysema. Retrieved March 5, 2005.. ... "Levels of Benzopyrene in Burnt toasts". Guardian Unlimited, Special reports: Close encounters. Retrieved March 5, 2005.. ... The substance with the formula C20H12 is one of the benzopyrenes, formed by a benzene ring fused to pyrene. Its diol epoxide ... The compound is one of the benzopyrenes, formed by a benzene ring fused to pyrene, and is the result of incomplete combustion ...
https://en.wikipedia.org/wiki/Benzo(a)pyrene
Benzo(a)pyreneBenzo(a)pyrene
"Benzopyrene and Vitamin A deficiency". Researcher links cigarettes, vitamin A and emphysema. Retrieved March 5, 2005.. ... 3,4-benzopyrene. 3,4-benz[a]pyrene. 3,4-benzo[a]pyrene. pentacyclo[10.6.2.02,7.09,19.016,20]icosa-1,3,5,7,9,11,13,15,17,19- ... "Levels of Benzopyrene in Burnt toasts". Guardian Unlimited, Special reports: Close encounters. Retrieved March 5, 2005.. ... The substance with the formula C20H12 is one of the benzopyrenes, formed by a benzene ring fused to pyrene. Its diol epoxide ...
https://en.wikipedia.org/wiki/Benzo
Benzo(a)pyreneBenzo(a)pyrene
Benzopyrene Benzo[e]pyrene Pyrene, a four-ring analogue Toxification Henri A. Favre, Warren H. Powell (2013). Nomenclature of ... The substance with the formula C20H12 is one of the benzopyrenes, formed by a benzene ring fused to pyrene. Its diol epoxide ... The compound is one of the benzopyrenes, formed by a benzene ring fused to pyrene, and is the result of incomplete combustion ... "Levels of Benzopyrene in Burnt toasts". Guardian Unlimited, Special reports: Close encounters. Retrieved March 5, 2005. Karle, ...
https://en.wikipedia.org/wiki/Benzo(a)pyrene
Health effects of tobaccoHealth effects of tobacco
Benzopyrene diol epoxide, an extremely carcinogenic (cancer-causing) metabolite of benzopyrene, a polycyclic aromatic ... "DNA interaction with Benzopyrene". DNA. Archived from the original on December 23, 2004. Retrieved March 5, 2005.. ... The first PAH to be identified as a carcinogen in tobacco smoke was benzopyrene, which has been shown to toxicate into an ... Benzopyrene, a major mutagen in tobacco smoke, in an adduct to DNA[161] ...
https://en.wikipedia.org/wiki/Health_effects_of_tobacco
Benzo(a)pyren - WikipedieBenzo(a)pyren - Wikipedie
V tomto článku byl použit překlad textu z článku Benzopyrene na anglické Wikipedii. ... Lung cancer as consequence by Benzopyrene in smokers [online]. [cit. 2005-03-05]. (Lung Cancer). Dostupné v archivu pořízeném ... Levels of Benzopyrene in Burnt toasts [online]. [cit. 2005-03-05]. (Guardian Unlimited). Dostupné online.. ... DNA interaction with Benzopyrene [online]. [cit. 2005-03-05]. (DNA). Dostupné online.. ...
https://cs.wikipedia.org/wiki/Benzo
Charcoal biscuitCharcoal biscuit
Food portal Activated charcoal Benzopyrene Disley, John (2006). CharcoalRemedies.com. Remnant Publications. ISBN 978-0-9738464- ...
https://en.wikipedia.org/wiki/Charcoal_biscuit
ParticulatesParticulates
These soot particles also carry carcinogens like benzopyrenes adsorbed on their surface. Particulate mass is not a proper ...
https://en.wikipedia.org/wiki/Particulates
Russian embargo of Ukrainian goodsRussian embargo of Ukrainian goods
29 July 2013). Kazakhstan did not find benzopyrene in the Roshen products. Ukrainian National News. (5 August 2013). Kyrgyzstan ...
https://en.wikipedia.org/wiki/Russian_embargo_of_Ukrainian_goods
Pacific Gas and Electric CompanyPacific Gas and Electric Company
4-benzopyrene and potassium chromate in mice drink". Arch Hyg Bakteriol. Carcinogens in water and soil. 152 (XXII): 45-53. ...
https://en.wikipedia.org/wiki/Pacific_Gas_and_Electric_Company
Hinkley groundwater contaminationHinkley groundwater contamination
4-benzopyrene and potassium chromate in mice drink". Arch Hyg Bakteriol. Carcinogens in water and soil. 152 (XXII): 45-53. PMID ...
https://en.wikipedia.org/wiki/Hinkley_groundwater_contamination
OstravaOstrava
Air condition in Ostrava is currently very poor, with high concentrations of benzopyrene. The pollution is so serious that it ... Measurements performed by the Czech Hydrometeorological Institute show that levels of atmospheric benzopyrene and dust ...
https://en.wikipedia.org/wiki/Ostrava
Benzo(e)pyreneBenzo(e)pyrene
Benzopyrene Benzo[a]pyrene Benzene Pyrene, a four-ring analogue v t e. ...
https://en.wikipedia.org/wiki/Benzo(e)pyrene
Arene oxideArene oxide
Benzopyrene is also converted to an epoxide, (+)-benzo[a]pyrene-7,8-epoxide. Benzene oxide (C6H6O) exists as an equilibrium ...
https://en.wikipedia.org/wiki/Arene_oxide
Jacques MillerJacques Miller
Miller, JF (1963). "Effect of thymectomy on the induction of skin tumours by 3,4-benzopyrene". Nature. 199 (4896): 920-2. ...
https://en.wikipedia.org/wiki/Jacques_Miller
EpoxideEpoxide
For prochiral arenes (naphthalene, toluene, benzoates, benzopyrene), the epoxides are often obtained in high enantioselectivity ...
https://en.wikipedia.org/wiki/Epoxide
YeosuanaYeosuana
... aromativorans is a species of non-motile aerobic marine bacterium that can degrade benzopyrene. It was first isolated ...
https://en.wikipedia.org/wiki/Yeosuana
Delitti e profumiDelitti e profumi
... benzopyrene-15). Eddy decides to find if there was a connection between the two victims and he discovers that each victim had ...
https://en.wikipedia.org/wiki/Delitti_e_profumi
Tobacco marketing targeting African AmericansTobacco marketing targeting African Americans
Brown began by explaining the ingredient menthol contains compounds such as benzopyrene, which is carcinogenic when smoked. He ...
https://en.wikipedia.org/wiki/Tobacco_marketing_targeting_African_Americans
Occupational cardiovascular diseaseOccupational cardiovascular disease
Associations also exist for exposure to arsenic, benzopyrenes, lead, dynamite, carbon disulphide, carbon monoxide, metalworking ...
https://en.wikipedia.org/wiki/Occupational_cardiovascular_disease
Chemical hazardChemical hazard
Associations also exist for exposure to arsenic, benzopyrenes, lead, dynamite, carbon disulphide, carbon monoxide, metalworking ...
https://en.wikipedia.org/wiki/Chemical_hazard
Del Amo (Superfund site)Del Amo (Superfund site)
... benzopyrene, phenanthrene and chrysene. Benzene is known to be a human carcinogen, and is detected most frequently and at the ...
https://en.wikipedia.org/wiki/Del_Amo_(Superfund_site)
Food safety incidents in TaiwanFood safety incidents in Taiwan
They also tested the tainted oil for any heavy metals, aflatoxin and benzopyrene, which may cause cancer in humans. However, ...
https://en.wikipedia.org/wiki/Food_safety_incidents_in_Taiwan
Heterocyclic amine formation in meatHeterocyclic amine formation in meat
Most of the 20 HCAs are more toxic than benzopyrene, a carcinogen found in cigarette smoke and coal tar. MeIQ, IQ and 8-MeIQx ...
https://en.wikipedia.org/wiki/Heterocyclic_amine_formation_in_meat
Ernst WynderErnst Wynder
Wynder also discovered specific carcinogens in tar (e.g., benzopyrenes, arsenic), but was unable to identify the contributions ...
https://en.wikipedia.org/wiki/Ernst_Wynder
PyrenePyrene
Although it is not as problematic as benzopyrene, animal studies have shown pyrene is toxic to the kidneys and liver. It is now ...
https://en.wikipedia.org/wiki/Pyrene
Oil well fireOil well fire
Smoke from burnt crude oil contains many chemicals, including sulfur dioxide, carbon monoxide, soot, benzopyrene, Poly aromatic ...
https://en.wikipedia.org/wiki/Oil_well_fire
Smokers melanosisSmoker's melanosis
Smoking or the use of nicotine-containing drugs is the cause to Smoker's melanosis,. Also tar-components (benzopyrenes) are ...
https://en.wikipedia.org/wiki/Smoker's_melanosis
FAM185AFAM185A
... and benzopyrene. These interactions are not yet confirmed for the human protein, FAM185A. Currently, no diseases are known to ...
https://en.wikipedia.org/wiki/FAM185A
Smoking banSmoking ban
Sidestream smoke contains 69 known carcinogens, particularly benzopyrene and other polynuclear aromatic hydrocarbons, and ...
https://en.wikipedia.org/wiki/Smoking_ban
Mycobacterium vanbaaleniiMycobacterium vanbaalenii
3-methylcholanthrene and benzopyrene. First isolated from an environmental source, not known to be pathogenic. Strain PYR-1 = ...
https://en.wikipedia.org/wiki/Mycobacterium_vanbaalenii
Benzopyrene - WikipediaBenzopyrene - Wikipedia
A benzopyrene is an organic compound with the formula C20H12. Structurally speaking, the colorless isomers of benzopyrene are ... Benzopyrene is a component of pitch and occurs together with other related pentacyclic aromatic species such as picene, ... Two isomeric species of benzopyrene are benzo[a]pyrene and the less common benzo[e]pyrene. They belong to the chemical class of ... Benzopyrenes are harmful because they form carcinogenic and mutagenic metabolites (such as (+)-benzo[a]pyrene-7,8-dihydrodiol-9 ...
https://en.wikipedia.org/wiki/Benzopyrene
Benzopyrene dictionary definition | benzopyrene definedBenzopyrene dictionary definition | benzopyrene defined
and known to be a cause of cancer in animalssometimes called benz·py′rene Origin of benzopyrene benzo- + pyrene... ... benzopyrene definition: an aromatic hydrocarbon, CH, found in coal tar, cigarette smoke, etc. ... benzopyrene. ben·zo·py·rene. an aromatic hydrocarbon, CH, found in coal tar, cigarette smoke, etc. and known to be a cause of ... benzopyrene. noun. Either of two polycyclic aromatic hydrocarbons with the formula C20H12, found in coal tar and cigarette ...
http://www.yourdictionary.com/benzopyrene
Brazilian scientists examine how benzopyrene can cause cancerBrazilian scientists examine how benzopyrene can cause cancer
http://agencia.fapesp.br/with_prevention_in_mind_researchers_investigate_how_benzopyrene_can_cause_cancer_/26427/ ...
https://www.news-medical.net/news/20171023/Brazilian-scientists-examine-how-benzopyrene-can-cause-cancer.aspx
Canary Database: Browse by Exposure: BenzopyrenesCanary Database: Browse by Exposure: Benzopyrenes
Browse by Exposure: Benzopyrenes (5 articles). % of records by year: 1965 2017 ...
http://canarydatabase.org/browse/exposure/5082
Polycyclic Aromatic Hydrocarbons - Compounds, Benzo, Organic, and Benzopyrene - JRank Articles Polycyclic Aromatic Hydrocarbons - Compounds, Benzo, Organic, and Benzopyrene - JRank Articles
Benzopyrene, for example, is an organic chemical with the general formula C20H12, containing a five-ring structure. Benzopyrene ... Some of the better known polycyclic aromatic compounds in environmental chemistry include anthracene, benzopyrene, ... There are various isomers, or structural variants of benzopyrene which differ greatly in their toxicological properties. The ...
http://science.jrank.org/pages/5398/Polycyclic-Aromatic-Hydrocarbons.html
benzopyrene: Topics by WorldWideScience.orgbenzopyrene: Topics by WorldWideScience.org
Benzopyrene monooxygenase (BPMO) values also seem to confirm such chemical stress. High levels of Hg and largely accumulated ... The main PAH, which cumulates in the organism is benzopyrene. This substance has been described by the IARC as a the most ... PBMC cells exposed to either benzopyrene (1 μM) or silymarin (2.4 mg/ml) or both was monitored for toxicity by assessing LPO, ... C) Benzopyrene, Vesselinovitch et al., 1975: Hepatic tumor incidence after single, parenteral administration to rats: - at day ...
https://worldwidescience.org/topicpages/b/benzopyrene.html
RCSB PDB - 2IA6: Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural GapRCSB PDB - 2IA6: Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural Gap
Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural Gap. *DOI: 10.2210/pdb2IA6/pdb ...
https://www.rcsb.org/structure/2IA6
benzopyrene | Definition of benzopyrene in US English by Oxford Dictionariesbenzopyrene | Definition of benzopyrene in US English by Oxford Dictionaries
Definition of benzopyrene in US English - a compound that is the major carcinogen present in cigarette smoke. It also occurs in ... Burnt toast (and, for that matter, barbecued or smoked meats) contains increased levels of a known carcinogen, benzopyrene. ... Wood fires can also release benzopyrene, a carcinogen that can irritate your eyes, nose, throat, and lungs. ... he admitted that the examination of the controversial benzopyrene is not included in the normal importation inspection. ...
https://en.oxforddictionaries.com/definition/us/benzopyrene
Field evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution | ScienceField evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution | Science
Field evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution ... Field evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution ... Field evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution ... Field evaluation of benzopyrene hydroxylase induction as a monitor for marine petroleum pollution ...
http://science.sciencemag.org/content/191/4230/945
Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice. | MRCBenzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice. | MRC
Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice.. ... Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice.. ...
http://www.environment-health.ac.uk/publications/benzo-pyrene-induced-dna-adducts-and-gene-expression-profiles-target-and-non-target
How benzopyrene in Latvian sprats leads to RussophobiaHow benzopyrene in Latvian sprats leads to Russophobia
... April 7 2014. 109 ... due to the high content of benzopyrene in it, which causes mutagenic effects on the human body. If we consider how much the ... also associated with the use of benzopyrene, responded to such an appeal "color of the nation." And whether Berzins uses ...
https://en.topwar.ru/43130-kak-benzapiren-v-latviyskih-shprotah-privodit-k-rusofobii.html
NIOSHTIC-2 Publications Search - 20041454 - Detection of polycyclic aromatic hydrocarbons (PAHS) in skin wipe samples of...NIOSHTIC-2 Publications Search - 20041454 - Detection of polycyclic aromatic hydrocarbons (PAHS) in skin wipe samples of...
NIOSHTIC-2 Publications Search - 20023853 - Biological monitoring for exposure to coal tar.NIOSHTIC-2 Publications Search - 20023853 - Biological monitoring for exposure to coal tar.
Benzopyrenes; Workplace-monitoring ...
https://www.cdc.gov/niosh/nioshtic-2/20023853.html
마더세이프라운드 임옥룡 cs2 0406 - English마더세이프라운드 임옥룡 cs2 0406 - English
Benzopyrene ; metabolically activated to the diol-epoxide derivative ; benzopyrene-trans-7,8- dihydrodiol-9, 10-epoxide, a ...
https://www.slideshare.net/mothersafe/cs20406
Cyclobenzaprine - do this medication cause to to have a positive drug test?Cyclobenzaprine - do this medication cause to to have a positive drug test?
Would cyclobenzaprine test positive for a drug test as a benzopyrene?. Posted 25 Feb 2010 • 1 answer ...
https://www.drugs.com/answers/cyclobenzaprine-do-this-medication-cause-to-to-246892.html
Benzo(a)pyrene - WikipediaBenzo(a)pyrene - Wikipedia
"Benzopyrene and Vitamin A deficiency". Researcher links cigarettes, vitamin A and emphysema. Retrieved March 5, 2005.. ... "Levels of Benzopyrene in Burnt toasts". Guardian Unlimited, Special reports: Close encounters. Retrieved March 5, 2005.. ... The substance with the formula C20H12 is one of the benzopyrenes, formed by a benzene ring fused to pyrene. Its diol epoxide ... The compound is one of the benzopyrenes, formed by a benzene ring fused to pyrene, and is the result of incomplete combustion ...
https://en.wikipedia.org/wiki/Benzo%28a%29pyrene
Benzo(a)pyrene - WikipediaBenzo(a)pyrene - Wikipedia
"Benzopyrene and Vitamin A deficiency". Researcher links cigarettes, vitamin A and emphysema. Retrieved March 5, 2005.. ... 3,4-benzopyrene. 3,4-benz[a]pyrene. 3,4-benzo[a]pyrene. pentacyclo[10.6.2.02,7.09,19.016,20]icosa-1,3,5,7,9,11,13,15,17,19- ... "Levels of Benzopyrene in Burnt toasts". Guardian Unlimited, Special reports: Close encounters. Retrieved March 5, 2005.. ... The substance with the formula C20H12 is one of the benzopyrenes, formed by a benzene ring fused to pyrene. Its diol epoxide ...
https://en.wikipedia.org/wiki/Benzo
Category:Polycyclic aromatic hydrocarbons - Wikimedia CommonsCategory:Polycyclic aromatic hydrocarbons - Wikimedia Commons
Hidrocarburo aromático policíclico (es); Policiklusos aromás szénhidrogének (hu); Hidrokarburo aromatiko polizikliko (eu); hidrocarbur aromàtic policíclic (ca); polycyclische aromatische Kohlenwasserstoffe (de); هیدروکربن آروماتیک چندحلقه‌ای (fa); 多環芳香烴 (zh); Aromatiske kulbrinter (da); Polisiklik aromatik hidrokarbon (tr); 多環芳香族炭化水素 (ja); Polycykliska aromatiska kolväten (sv); פחמימנים ארומטיים רב-טבעתיים (he); 多環芳香烴 (zh-hant); 多环芳香烃 (zh-cn); 多环芳香烃 (wuu); Polysykliset aromaattiset hiilivedyt (fi); policikla aromata hidrokarbono (eo); polyaromatické uhlovodíky (cs); idrocarburi policiclici aromatici (it); hydrocarbure aromatique polycyclique (fr); Polütsüklilised aromaatsed süsivesinikud (et); 多環芳香烴 (zh-tw); Policikliniai aromatiniai angliavandeniliai
https://commons.wikimedia.org/wiki/Category:Polycyclic_aromatic_hydrocarbons
The EPA National Library Catalog | EPA National Library Network | US EPAThe EPA National Library Catalog | EPA National Library Network | US EPA
C20H12 ; 1,2-benzopyrene ; 3,4-benzopyrene. Holdings. Library. Call Number. Additional Info. Location. Last. Modified. Checkout ...
https://cfpub.epa.gov/ols/catalog/advanced_bibliography.cfm?&FIELD1=SUBJECT&INPUT1=Coke%20industry&TYPE1=EXACT&LOGIC1=AND&COLL=&SORT_TYPE=MTIC&start_row=2
Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyreneMitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene
Benzopyrenes / metabolism* * Cell Line * Cell Nucleus / metabolism * DNA Replication / drug effects * DNA, Mitochondrial / ...
https://pubmed.ncbi.nlm.nih.gov/6770466/
Sampling and Analytical Methods | Coal Tar Pitch Volatiles (CTPV), 58Sampling and Analytical Methods | Coal Tar Pitch Volatiles (CTPV), 58
3,4-benzopyrene; 6,7-benzopyrene. structure:. Figure 1.1.4. Benzene-soluble fraction (The sum of those components collected on ...
https://www.osha.gov/dts/sltc/methods/organic/org058/org058.html
OSHA Chemical Database | Occupational Safety and Health AdministrationOSHA Chemical Database | Occupational Safety and Health Administration
Substance Priority List | ATSDRSubstance Priority List | ATSDR
BENZOPYRENE. 603. 73467-76-2. 231. CHLORDANE, TECHNICAL. 602. 12789-03-6. ...
https://www.atsdr.cdc.gov/spl/index.html
2013 ATSDR Substance Priority List | Substance Priority List | ATSDR2013 ATSDR Substance Priority List | Substance Priority List | ATSDR
BENZOPYRENE. 603.4. 225. 073467-76-2. 227. CHLORDANE, TECHNICAL. 602.5. 226. 012789-03-6. ...
https://www.atsdr.cdc.gov/spl/resources/2013_atsdr_substance_priority_list.html
Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase...Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase...
... including curved backbone and cardiomegaly in zebrafish were observed in the 54 hpf with more than 400 nM of benzopyrene. In ... lamin-A/C isoform 3 and annexin A1 for benzopyrene; lamin-A/C isoform 3 and DNA topoisomerase 2-alpha for pentacene; poly[ADP- ... Benzopyrene (BaP) among 32 PAH compounds is notable for being the first chemical carcinogen to be discovered [2, 3]. ... DMSO, only DMSO-treatment as control; PARP-1, poly[ADP-ribose] polymerase 1; LMNA, lamin A/C; BaP, benzopyrene.. ...
https://www.hindawi.com/journals/bmri/2014/605135/
Inhibition of benzo pyrene- and cyclophosphamide-induced mutagenicity by Cinnamomum cassia - ABIM - An Annotated Bibliography...Inhibition of benzo pyrene- and cyclophosphamide-induced mutagenicity by Cinnamomum cassia - ABIM - An Annotated Bibliography...
Inhibition of benzo pyrene- and cyclophosphamide-induced mutagenicity by Cinnamomum cassia. Type of publication:. Article / ... 2001) Inhibition of benzo pyrene- and cyclophosphamide-induced mutagenicity by Cinnamomum cassia. [Publication] ...
https://indianmedicine.eldoc.ub.rug.nl/10599/
Antibodies against homogeneous epoxide hydratase provide evidence for a single enzyme hydrating styrene oxide and benz(a)pyrene...Antibodies against homogeneous epoxide hydratase provide evidence for a single enzyme hydrating styrene oxide and benz(a)pyrene...
Benzopyrenes / metabolism * Carcinogens / metabolism * Epoxide Hydrolases / immunology * Epoxide Hydrolases / metabolism* * ...
https://pubmed.ncbi.nlm.nih.gov/1250340/?dopt=Abstract
The frequency of polychromatic erythrocytes (PE) in the relation with erythrocytes normochromic (NE) in rats (R) treated whit...The frequency of polychromatic erythrocytes (PE) in the relation with erythrocytes normochromic (NE) in rats (R) treated whit...
Benzo[a]pyreneBenzo[a]pyrene
Other names: Benz[a]pyrene; 1,2-Benzpyrene; 3,4-Benzopyrene; 3,4-Benzpyrene; 3,4-Benz[a]pyrene; 6,7-Benzopyrene; Benzo[d,e,f] ... chrysene; B(a)P; BP; 3,4-Benzopirene; 3,4-Benzpyren; 3,4-BP; Rcra waste number U022; Benzopyrene; 4,5-Benzpyrene; NSC 21914; ...
https://webbook.nist.gov/cgi/cbook.cgi?ID=C50328&Units=CAL&Mask=FFFF
MEDLINE - Resultado p gina 1 MEDLINE - Resultado p gina 1
0 (Benzopyrenes); 0 (DNA Adducts); 0 (benzo(a)pyrene N2-dG adduct); EC 2.7.7.- (DNA Polymerase I); EC 2.7.7.- (DNA Polymerase ...
http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=D08.811.913.696.445.308.300.225
BenzoPolycyclic aromatic hydPyreneCompoundsBenzeneCarcinogenicIsomersLungAntibodyBenzanthraceneMutagenicCoalOrganicRatsLiverNeoplasticCharcoalResearchersHarmfulCellsFoundAnimalsLevelsNormalMainDrug
Benzo2
  • Two isomeric species of benzopyrene are benzo[a]pyrene and the less common benzo[e]pyrene. (wikipedia.org)
  • Benzopyrenes are harmful because they form carcinogenic and mutagenic metabolites (such as (+)-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide from benzo[a]pyrene) which intercalate into DNA, interfering with transcription. (wikipedia.org)
Polycyclic aromatic hyd1
  • In February 2014, NASA announced a greatly upgraded database for tracking polycyclic aromatic hydrocarbons (PAHs), including benzopyrene, in the universe. (wikipedia.org)
Pyrene3
  • Structurally speaking, the colorless isomers of benzopyrene are pentacyclic hydrocarbons and are fusion products of pyrene and a phenylene group. (wikipedia.org)
  • The substance with the formula C 20 H 12 is one of the benzopyrenes , formed by a benzene ring fused to pyrene . (wikipedia.org)
  • The compound is one of the benzopyrenes , formed by a benzene ring fused to pyrene , and is the result of incomplete combustion at temperatures between 300 °C (572 °F) and 600 °C (1,112 °F). (wikipedia.org)
Compounds5
  • Benzopyrene (BaP) among 32 PAH compounds is notable for being the first chemical carcinogen to be discovered [ 2 , 3 ]. (hindawi.com)
  • They may also inhibit the binding of nucleic acids to benzopyrenes and related compounds. (harvard.edu)
  • Cooking food at temperatures over 180ºC promotes formation of several carcinogenic compounds, including aromatic hydrocarbon, benzopyrene, and heterocyclic amine (HCA). (mercola.com)
  • Exposure of food to high cooking temperatures (over 180ºC) such as with oven roasting or frying can lead to the formation of toxic carcinogenic compounds which include aromatic hydrocarbon, benzopyrene and heterocyclic amine. (mercola.com)
  • These are four volatile oil compounds that help neutralize the benzopyrenes found in cigarette smoke as well as in charcoal grill smoke. (hubpages.com)
Benzene1
  • Benzopyrene is extremely insoluble in water but very soluble in certain organic solvents such as benzene. (jrank.org)
Carcinogenic2
  • It also included benzopyrene, which smells nice but is highly carcinogenic. (gadling.com)
  • G]inseng exhibited beneficial effects on the detoxification of a carcinogenic compound, benzopyrene. (quackwatch.org)
Isomers1
  • There are various isomers, or structural variants of benzopyrene which differ greatly in their toxicological properties. (jrank.org)
Lung5
  • Full Text Available This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA on rat's cancer model exposed with benzopyrene , and the histology of its lung. (worldwidescience.org)
  • The isolated fraction contained of these metabolites significantly indicate bioactivity by reducting of malondialdehyde (MDA level, and also histology appearance of the lung tissue prepared from the benzopyrene -exposed rat indicated a curative activity. (worldwidescience.org)
  • Statistical eliminative process shows 3:4- benzopyrene (BP) to be the hydrocarbon of prime importance in lung cancer and bronchitis, with 1:12 benzoperylene contributing. (worldwidescience.org)
  • Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression. (bvsalud.org)
  • Furthermore, Zhao et al ( 16 ) demonstrated that benzopyrene (BaP) may promote lung cancer cell metastasis by activating the tumor necrosis factor-α signaling pathway. (spandidos-publications.com)
Antibody2
  • A team led by Prof. Arne Skerra from the Technical University of Munich (TUM) has deciphered the binding mechanism of an antibody to benzopyrene - a discovery that could pave the way for an easier method to identify and, hence, remove the toxin. (tum.de)
  • The antibody-based nanoprobe was used for in situ measurements of benzopyrene tetrol in single cells. (springer.com)
Benzanthracene1
  • Using cell proliferation and apoptosis assays, it was demonstrated that benzopyrene (BaP) suppressed the proliferation of mLFCs, and benzanthracene (BaA) and BaP induced cell apoptosis. (spandidos-publications.com)
Mutagenic1
  • Apparently, it was not in vain that the Russian sanitary inspectors at one time so advocated a ban on the Latvian canned product "Sprats in oil" due to the high content of benzopyrene in it, which causes mutagenic effects on the human body. (topwar.ru)
Coal1
  • However, when fat reacts with glowing coal, a substance chemists call benzopyrene is created. (tum.de)
Organic3
  • A benzopyrene is an organic compound with the formula C20H12. (wikipedia.org)
  • Benzopyrene, for example, is an organic chemical with the general formula C 20 H 12 , containing a five-ring structure. (jrank.org)
  • Other countries, such as Japan and the United States, did not set specific standards for benzopyrene in smoked fish products, but recommended its industries to voluntarily reduce the presence of the said organic compound to the lowest possible level," the statement read. (thepinoy.com)
Rats1
  • The frequency of polychromatic erythrocytes (PE) in the relation with erythrocytes normochromic (NE) in rats (R) treated whit benzopyrene. (scholars.direct)
Liver1
  • Fish from petroleum-contaminated sites in the marine environment have elevated levels of benzopyrene hydroxylase activity in liver and gill tissue. (sciencemag.org)
Neoplastic1
  • Rights & permissions for article Metabolic degradation of 3,4-benzopyrene in the cultures of normal and neoplastic fibroblasts. (nature.com)
Charcoal1
  • Fumes that develop from fat dripping on blistering charcoal are rich in benzopyrene, which can condense on grilled goods. (wikipedia.org)
Researchers1
  • Researchers estimated that every day the average infant under the age of two in urban America ingested 110 nanograms of benzopyrene, equivalent to smoking three cigarettes a day. (oxforddictionaries.com)
Harmful1
  • In a statement, it said KFDA had conducted a thorough test and issued a certificate on Nov. 7, 2012 saying that the level of benzopyrene found in the noodle powder-which ranges from 0.4 to 1.6 ppb-"was extremely low and has no harmful effect on the human body. (thepinoy.com)
Cells2
  • Macrophages promote benzopyrene-induced tumor transformation of human bronchial epithelial cells by activation of NF-κB and STAT3 signaling in a bionic. (oncotarget.com)
  • We investigated the role of macrophages in promoting benzopyrene (BaP)-induced malignant transformation of human bronchial epithelial cells using a BaP-induced tumor transformation model with a bionic airway chip in vitro and in animal models. (oncotarget.com)
Found1
  • Tests of medications purchased online have found PCBs (polychlorinated biphenyls) and benzopyrenes in fake medication purchased for the tests. (safemedicines.org)
Animals1
  • Animals in group A and group B were given 3,4- benzopyrene -corn oil mixture pulmonary injection fortnightly for 4 times, while in group C corn oil only. (worldwidescience.org)
Levels1
  • Burnt toast (and, for that matter, barbecued or smoked meats) contains increased levels of a known carcinogen, benzopyrene. (oxforddictionaries.com)
Normal1
  • Although legally imported olive oil has passed the required quarantine inspection, he admitted that the examination of the controversial benzopyrene is not included in the normal importation inspection. (oxforddictionaries.com)
Main1
  • NER is the main mechanism used to remove pyrimidine dimers induced by UV cross-linking or chemical damage such as those caused by benzopyrene, aflatoxin, and cisplatin. (oxforddictionaries.com)
Drug1
  • Would cyclobenzaprine test positive for a drug test as a benzopyrene? (drugs.com)
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