A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it.
A central nervous system stimulant. It was formerly used in the treatment of barbiturate overdose but is now considered to be of no value for such purposes and may be dangerous. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1229)
An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water. EC 1.14.16.2.
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.

Inhibition of benzo(alpha)pyrene metabolism catalyzed by mouse and hamster lung microsomes. (1/54)

Induced and constitutive microsomal enzymes of mouse and hamster lungs catalyze both the hydroxylation of benzo(alpha)pyrene and reactions that lead to its irreversible binding to macromolecules. For mouse and hamster, the induced lung hydroxylases have Km values of 1.10 and 0.52 muM, respectively. The induced hydroxylases are strongly inhibited by 7,8-benzoflavone and are stimulated by cyclohexene oxide, an inhibitor of epoxide hydrase. Formation of the macromolecular product by the induced "binding" enzyme follows. Michaelis-Menten kinetics, except for substrate inhibition, and has Km values of 0.52 and 0.25 muM for lung microsomes from mouse and hamster, respectively. These reactions are also inhibited by 7,8-benzoflavone. The reaction catalyzed by the constitutive hydroxylase of mouse lungs is characterized by a brief lag period but proceeds in a linear fashion after the lag. The enzyme requires 60 muM benzo(alpha)pyrene to achieve maximum reaction velocity. Above this concentration, strong substrate inhibition is observed; accurate values for Vmax and Km cannot be derived. The constitutive hydroxylases are moderately inhibited by butylated hydroxytoluene, retinol, cyclohexene oxide, and 7,8-benzoflavone. The product of the constitutive "binding" enzyme is formed in a reaction that follows Michaelis-Menten kinetics. The Km value for enzymes from mouse and hamster lungs are 11.8 and 4.9 muM, respectively. Formation of this product is strongly inhibited by butylated hydroxytoluene and by retinol but not strongly by 7,8-benzoflavone or cyclohexene oxide. Since other evidence indicates that a constitutive enzyme may be involved in carcinogenesis by benzo(alpha)pyrene and since this reaction is inhibited by two known anticarcinogens, we suggest that it may be involved in this process.  (+info)

The atherogen 3-methylcholanthrene induces multiple DNA adducts in mouse aortic smooth muscle cells: role of cytochrome P4501B1. (2/54)

OBJECTIVE: 3-Methylcholanthrene (MC), a polycylic aromatic hydrocarbon, induces atherogenesis in mice fed an atherogenic diet. In this study, we tested the hypothesis that MC would induce DNA adducts in mouse aortic smooth muscle cells (SMCs) and that cytochrome P4501B1 (CYP1B1) plays an important role in the activation of MC to genotoxic intermediates. METHODS: Cultured SMCs were treated with MC or the vehicle dimethyl sulfoxide (DMSO), and DNA was isolated after 24 h. In some experiments, the cells were pre-treated with the CYP1B1 inhibitor 1-ethynylpyrene (EP) prior to exposure to MC. DNA adducts were determined by the 32P-postlabeling assay. Aryl hydrocarbon hydroxylase assay was measured by fluorimetry. RESULTS: MC induced formation of 12 DNA adducts that were not observed in DMSO-treated cells. DNA adduct formation was dose-dependent, with maximum response observed at 3 microM. Pre-treatment of cells with EP dramatically suppressed DNA adduct formation by MC. MC treatment caused induction of CYP1B1, but not CYP1A1. CONCLUSION: The induction of high levels of multiple DNA adducts in SMCs by MC suggests that SMCs have a functional enzymatic machinery capable of metabolically activating MC to genotoxic metabolites. The significant inhibition by EP of MC-induced DNA adduct formation indicated that CYP1B1 was the primary CYP enzyme responsible for formation of genotoxic metabolites that may play a role in the induction of atherosclerosis by MC.  (+info)

Development of an assay for aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes. (3/54)

An assay has been developed and measurements of aryl hydrocarbon [benzo(a)pyrene] hydroxylase have been made in peripheral blood monocytes from a human population. Treatment with benz(a)anthracene in cell culture increased aryl hydrocarbon hydroxylase activity from 6.5 to 37-fold in monocytes from each of 25 apparently healthy donors. A weak correlation (r = 0.38) was observed between the induction ratios obtained with monocytes and lymphocytes from the same donors. Reproducibilities of the monocyte and lymphocyte assays were comparable. In monocytes, the measurement of basal and induced aryl hydrocarbon hydroxylases activity does not require pretreatment with mitogens as is the case with lymphocytes. Monocytes also exhibit a much wider range of induction ratios than do lymphocytes.  (+info)

Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo. (4/54)

We have analyzed dioxin-inducible, Ah receptor-dependent changes in protein-DNA interactions at the CYP1A1 transcriptional promoter in intact mouse hepatoma cells. Our findings indicate that in uninduced cells, the promoter is inaccessible to its cognate binding proteins, which are known to be expressed constitutively. Dioxin induces, in Ah receptor-dependent fashion, an increase in promoter accessibility, which occurs rapidly and does not require ongoing transcription of the CYP1A1 gene. The change in promoter accessibility is not due to an altered pattern of cytosine methylation at the promoter; it probably reflects a 2,3,7,8-tetrachlorodibenzo-p-dioxin- induced change in the chromatin structure. These findings provide new insight into the mechanism of dioxin action and contribute to a better understanding of the regulation of inducible gene transcription in mammalian cells.  (+info)

Regulation of aryl hydrocarbon (benzo-(A)-pyrene) hydroxylase activity in mammalian cells. Induction of hydroxylase activity by N6,O2'-dibutyryl8 adenosine 3':5'-monophosphate and aminophylline. (5/54)

Treatment of hamster BHK cells with N6,O2'-dibutyryl adenosine 3':5'-monophosphate (Bt2cAMP), aminophylline, theophylline, or papaverine increased the level of aryl hydrocarbon (benzo(a)pyrene) hydrolxylase activity. The highese increase, 100-fold, was obtained with Bt2cAMP plus aminophylline or theophylline. N2,O2-Dibutyryl guanosine 3':5'-monophosphate gave a lower induction than Bt2cAMP. The level of hydroxylase activity started to decrease 6 hours after treatment with the inducer and was reduced to almost the uninduced level after 24 hours. Repeated addition of Bt2cAMP and aminophylline did not prevent this decrease. The hydroxylase can also be induced by treating cells with benz(a)anthracene, and the level of this induced activity was maintained for 24 hours. Aminophylline gave a 2- to 8-fold stimulation of the induction by benz(a)anthracene. The enzyme activity induced by Bt2cAMP, aminophylline, and benz(a)anthracene converted benzo(a)pyrene to similar alkali-extractable metabolities with a fluorescence spectra similar to that of 3-hydroxybenzo(a)pyrene. These induced enzyme activities also showed a similar heat stability. Induction by Bt2cAMP and aminophylline, like induction by benz(a)anthracene, required continued protein synthesis and only an initial period of RNA synthesis. Compared to the benz(a)anthracene-induced hydroxylase with a Km of 4.3 muM, the hydroxylase induced by Bt2cAMP and aminophylline showed a Km of 0.14 muM, and was 100-fold more sensitive to inhibition by 7,8-benzoflavone. Increasing the serum concentration in the culture medium stimulated the induction by aminophylline but did not stimulate induction by benz(a)anthracene. The results indicate that aryl hydrocaarbon (benzo(a)pyrene) hydroxylase can be induced by compounds that increase the level of adenosine 3':5'-monophosphate and that this induction and induced enzyme activity differs from that caused by benz(a)anthracene.  (+info)

Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases. (6/54)

The parenteral administration of a single dose of 3-methylcholanthrene to rats caused an increase in the liver of the concentration of 3', 5'-cAMP and of the activity of cAMP-dependent protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37). These events were followed by an increased activity of ornithine decarboxylase (L-ornithine carboxy-lase, EC 4.1.1.17), the enzyme that controls the biosynthesis of polyamines. Finally, the activity of benzo[a]pyrene hydroxylase, as well as the amount of cytochrome P-448, was increased. Similarly, after the administration of phenobarbital, there was first an increase in the cAMP concentration and in the activity of cAMP-dependent protein kinase, then the induction of ornithine decarboxylase, and finally, an enhanced activity of ethylmorphine N-demethylase and an increased content of cytochrome P-450. These data suggest that the drug-induced processes in liver that increase the activities of the oxidative, and presumably other, drug-metabolizing enzymes include the following sequence of events: (1) increase in cAMP concentration and/or activation of cAMP-dependent protein kinase; (2) induction of ornithine decarboxylase; and, (3) induction of drug-metabolizing enzymes.  (+info)

NADH-dependent aryl hydrocarbon hydroxylase in rat liver mitochondrial outer membrane. (7/54)

NADH-dependent 3,4-benzpyrene hydroxylase activity was detected in the purified mitochondrial outer membrane fraction from the livers of rats treated with 3-methylcholanthrene. The specific activity in the outer membrane fraction is nearly equal to that of microsomes, a level too high to be accounted for only by the microsomal contamination. On the other hand, the NADPH-dependent 3,4-benzpyrene hydroxylase activity in the outer membrane fraction is about 50% of that of microsomes. The ratio of the specific activity of NADPH- to NADH-dependent 3,4-benzpyrene hydroxylase in microsomal fraction was about 3.5, while that of the outer membrane fraction was about 1.5. Moreover, it was found that NADH-dependent 3,4-benzpyrene hydroxylase activity in mitochondrial outer membrane from control rat liver was cyanide-insensitive, while that in microsomes was cyanide-sensitive. These results suggest the presence in the mitochondrial outer membrane fraction of aryl hydrocarbon hydroxylase activity which uses as electron donor NADH nearly to the same extent as NADPH. The hydroxylase system is composed of cyanide-insensitive cytochrome P-450 and is inducible markedly by 3-methylcholanthrene treatment. The probable electron transfer pathways in the mitochondrial outer membrane cytochrome P-450 oxidase system are discussed.  (+info)

A relative deficiency of cytochrome P-450 and aryl hydrocarbon [benzo(a)pyrene] hydroxylase in hyperplastic nodules induced by 2-acetylaminofluorene in rat liver. (8/54)

The concentrations of cytochrome P-450 and the activities of aryl hydrocarbon [benzo(a)pyrene] hydroxylase (AHH) and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase were measured in early (gray-white) and remodeled (brown) hyperplastic nodules induced in the livers of rats with 2-acetylaminofluorene and were compared to the values in control livers and in the liver surrounding the nodules. Cytochrome P-450 content of early (14 weeks) hyperplastic nodules is 30% of the activity of untreated control livers and 48% of the activity of the surrounding liver. AHH activity of the early nodules is 10% of the control activity and 33% of the activity in the surrounding nonnodular liver. Nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity in the microsomes of early nodules is 76% of the control activity and 78% of the activity in the surrounding liver. In the late remodeled nodules, (22 and 25 weeks), the cytochrome P-450 content is 40% of that of controls and AHH activity is 15% of the control activity. In primary hepatomas induced by 2-acetylaminofluorene, cytochrome P-450 content is 21% of that of controls, AHH activity is 11% of the activity of controls, and reductase is 50% of the control activity. These results, indicating a relative nodule deficiency in some of the cellular components believed to be important in the activation of hepatocarcinogens and hepatotoxins, offer one possible explanation for the relative resistance to carcinogen cytotoxicity of hyperplastic liver nodules.  (+info)

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History Interleukin-8 (IL-8) features as a significant chemoattractant and has pivotal jobs in the initiation and advancement of chronic obstructive pulmonary disease TMC 278 (COPD) and cigarette smoke cigarettes is a most risk aspect contributing to the introduction of COPD. cells was dependant on cell counting package-8 package luciferase activity was measured in reporter gene-expressing 16HEnd up being cells and IL-8 amounts in lifestyle supernatants had been quantified by enzyme-linked immunosorbent assay. Outcomes On the nontoxic dosages chemical substances owned by nicotine aromatic amines benzopyrene phenols aldehydes plus some various other volatile organics dose-dependently elevated reporter gene appearance. Consistently the TMC 278 consultant compounds belonging to nicotine aromatic amines benzopyrene phenols aldehydes and some other volatile organics significantly and dose-dependently increased IL-8 levels in TMC 278 the culture supernatants of 16HBE cells among these compounds ...
4.1 Polymorphisms and mutations are both variations in DNA sequence and can arise through the same mechanisms. We use the term polymorphism to refer to DNA variants that are relatively common in populations. Mutations affect the phenotype.. 4.2 Misreading of bases during replication can lead to substitution and can be caused by things like tautomerism, DNA alkylating agents, and irradiation.. 4.3 Looping out of DNA on the template strand during replication; strand breakage, due to radiation and other mutagens; and (discussed in earlier chapters) chromosomal aberrations such as deletions and translocations.. 4.4 Looping out of DNA on the growing strand during replication; transposition; and (discussed in earlier chapters) chromosomal aberrations such as duplications, insertions, and translocation.. 4.5 Benzopyrene is one of many hazardous compounds present in smoke. Benzopyrene is an intercalating agent, which slides between the bases of the DNA molecule, distorting the shape of the double helix, ...
Trifluralin - ZSDSQXJSNMTJDA-UHFFFAOYSA-N - Trifluralin [ANSI:BSI:ISO] - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Trifluralin market on the basis of type, application, and geography. This report provides a quantitative analysis of the current trends and estimations to 2025
The present study shows the effect of combined dietary deprivation of fat and vitamin A on benzo(a)pyrene (BaP) induced lung carcinogenesis in male Wistar rats. Lung tumors were induced by intratracheal instillation of BaP-Fe2O3 in normal saline. The tumor incidence and tumor burden in control animals were 82% and 2.28 respectively. Fat deficiency decreased the tumor incidence to 57% and tumor burden to 1.66. On the other hand, in vitamin A deficiency these were 83% and 4.02 respectively. Fat deprivation in the diet of animals fed with vitamin A deficient diet decreased the tumor incidence and tumor burden to 69.6% and 2.7 respectively. The results suggest a protective role of low intake of fat in vitamin A deficiency for BaP-induced lung tumorigenesis in rats.
The toxicity of formalin and trifluralin to the larval stages of the mud crab Scylla serrata was compared in a static bioassay. Prophylactic doses of 5, 10, 15, 20 and 25 μg L−1 formalin and 0.05, 0.1, 0.2, 0.4 and 0.8 μg L−1 trifluralin were used. Toxicity was assessed on the basis of survival of larvae after 24, 48, 72 and 96 h exposure to the test chemicals and metamorphosis to the next larval stage. Result shows that larval survival in all stages was significantly reduced at concentrations of 20 and 25 μg L−1 formalin whereas larvae were able to tolerate all trifluralin treatments. However, larvae became more tolerant to high formalin concentrations as the larval stage progressed. Survival was better at 5, 10 and 15 μg L−1 formalin and in all trifluralin treatments than the control in almost all the larval stages. Faster metamorphosis was observed at 5 and 10 μg L−1 formalin and 0.05, 0.1 and 0.2 μg L−1 trifluralin concentrations. Doses of formalin and trifluralin obtained ...
Classification is based on the induction of urinary tract tumors (renal pelvis carcinomas and urinary bladder papillomas) and thyroid tumors (adenomas/carcinomas combined) in one animal species (F344 rats) in one study. Trifluralin is structurally similar to ethalfluralin, a carcinogen in the rat ...
The BIOBARRIER System manages roots through the slow, controlled release of trifluralin, a root inhibition herbicide that has been in use on food crops in the United States for more than 35 years. A pattern of 7/16-inch-hemisphere nodules is through-injection-molded to 4-ounce-per-square-yard, durable, proven TYPAR® geotextile fabric on 1.5-inch centers. This creates a continuous zone of root control protection.. Trifluralin diffuses from the protective nodules in vapor form, creating a root inhibition zone in the soil. Roots penetrate the zone until root tips reach the herbicidal concentration that prevents that species root tip cell division; this is normally 3/8 inches from the fabric. Only the root tip cells ability to divide and grow is affected; neither the plant nor its roots are killed because trifluralin is not systemic. The BIOBARRIER System simply diverts the roots and causes the plant to concentrate growth in branch roots away from the trifluralin zone.. Click this Direct Link to ...
Words Ending In ene: acetylene,achene,advene,agene,akene,alkene,amene,aminobutene,amylene,anadyomene,anthracene,antigene,antivenene,arrasene,azobenzene,bene,benzanthracene,benzene,benzoapyrene,benzopyrene,benzpyrene,buckm
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. ...
Hydrase definition, any of the class of enzymes that catalyze the addition of a water molecule into a compound without causing hydrolysis. See more.
Words starting with T (page 84): triffic, triffid, triffidian, triffids, triffidy, trifid, trifle, trifled, trifler, trifles, trifling, triflingly, triflingness, triflings, trifluoperazine, trifluralin, trifocal, trifold, trifoliate, trifoliated...
This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is cis-stilbene-oxide hydrolase. Other names in common use include epoxide hydratase (ambiguous), microsomal epoxide hydratase (ambiguous), epoxide hydrase, microsomal epoxide hydrase, arene-oxide hydratase (ambiguous), benzo[a]pyrene-4,5-oxide hydratase, benzo(a)pyrene-4,5-epoxide hydratase, aryl epoxide hydrase (ambiguous), cis-epoxide hydrolase, and mEH. This enzyme participates in metabolism of xenobiotics by cytochrome p450 ...
2 major biochemical reactions that occur in the peroxisome is the mixed function oxidase and the other is a catalase but what 2 enzymes are involved in these reactions?...beta oxidation one of them ...
Trichloroepoxypropane: A potent epoxide hydrase and aryl hydrocarbon hydroxylase inhibitor. It enhances the tumor-initiating ability of certain carcinogens.
Effects of five organic solvent vehicles on benzo(a)pyrene- hydroxylase (BP-hydroxylase) activity and on the benzo(a)pyrene (50328) (BP) metabolite profile were studied in lung microsomes prepared from male New Zealand white rabbits. The production of 3- OH-benzo(a)pyrene (13345216) and 9-OH-benzo(a)pyrene (17573216) was used to evaluate the effects of dimethyl-sulfoxide (DMSO), acetone, methanol,
soil pollution; phenanthrenes; fertilizer application; nitrogen; bioremediation; soil amendments; alkaline soils; lacustrine soils; soil microorganisms; biosolids; biodegradation; phosphorus; saline soils; benzopyrenes; polluted soils; nitrogen fertilizers; ...
TY - JOUR. T1 - Binding of Metabolically Activated Benzo(A)Pyrene to Nuclear Macromolecules. AU - Pezzuto, John M.. AU - Lea, Michael A.. AU - Yang, Chung S.. PY - 1976/10. Y1 - 1976/10. N2 - The binding of metabolically activated [3 H]benzo(a)pyrene ([3 H]BP) to the DNA, RNA, histones, and nonhistones of isolated rat liver and lung nuclei was studied. Conditions for optimal binding to the nuclear components were determined. Upon incubation with isolated liver nuclei and reduced nicotinamide adenine dinucleotide phosphate, [3 H]BP was able to bind to nuclear components. The binding appeared to be covalent in nature. Treatment of the rats with 3-methylcholanthrene induced the nuclear aryl hydrocarbon hydroxylase (AHH) activity and also increased the level of carcinogen binding. The addition of rat liver microsomes to the incubation systems greatly enhanced the level of [3 H]BP binding to the macromolecules in the nuclei from both the control and 3-methylcholanthrene-treated rats, and the maximal ...
en] Cytochrome P-450-dependent monooxygenases are able to oxidize a large variety of endogenous and exogenous substrates. This paper describes the in vitro interaction between benzopyrene and steroids at the level of two rat liver monooxygenases: steroid-16 alpha-hydroxylase and aryl hydrocarbon hydroxylase (AHH). The results obtained suggest the following conclusions: (1) Steroid-16 alpha-hydroxylase is partially supported by a specific cytochrome P-450 form which is not inhibited in vitro by exogenous substrates. Steroid-16 alpha-hydroxylase is completely independent from cytochrome P1-450 (or P-448), as it is insensitive, in vitro, to alpha-naphthoflavone; (2) AHH is supported by two cytochrome P-450 forms: a specific form which is inducible by methylcholanthrene and inhibited in vitro by alpha-naphthoflavone, but is insensitive to metyrapone and steroids; and another less specific form which is inhibited by metyrapone and steroids in vitro ...
Download Free Full-Text of an article EFFECTS OF 3 - METHYL CHOLANTHEREN ON LIVER MICROSOMAL MIXED FUNCTION OXIDASE ACTIVITIES OF ACIPENSER PERSICUS
Brundel, dang, I dont like hearing that about 7, 8 benzoflavone . I was about to pick up several bottles of Dermacrine when they were back in stock.
We measured aryl hydrocarbon hydroxylase (AHH) in cultured human lymphocytes. A striking seasonal variation in AHH activity was observed with induced AHH activity levels from January through May measuring approximately 20% of the values during the remainder of the year. AHH inducibility was determined by comparing lymphocytes from the same person cultured with and without the inducer 3-methylcholanthrene. If measurements are limited to the summer and fall seasons when AHH activity is high, AHH inducibility is reproducible for most persons with repeat determinations on the same person averaging 11% from the mean. The values of AHH inducibility in 53 persons ranged from 0.9 to 5.0, but the distribution of values did not fall into three distinct, nonoverlapping classes as reported by others. We were not able to determine the distribution of AHH inducibility in lung cancer patients since lymphocytes from less than half of the patients tested could be successfully cultured.
Lee, S.-M. and Clemens, M. G. (1992), Effect of α-tocopherol on hepatic mixed function oxidases in hepatic ischemia/reperfusion. Hepatology, 15: 276-281. doi: 10.1002/hep.1840150217 ...
The rat and hamster exhibit about a 100-fold difference in sensitivity to the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), with the hamster representing the most resistant species examined to date. The present study compared the induction and inhibition of hepatic TCDD metabolism in these species using suspensions of isolated hepatocytes. Purified 14C-TCDD or 3H-TCDD (2.2 microM) was incubated for 2-6 hr with hepatocytes isolated from untreated, TCDD-pretreated (5 micrograms/kg, ip), 3-methylcholanthrene-pretreated (3-MC, 50 mg/kg, ip, x 3 days), isosafrole-pretreated (ISO, 150 mg/kg, ip, x 3 days), or phenobarbital-pretreated (PB, 80 mg/kg, ip, x 3 days) rats and hamsters. Untreated rat and hamster hepatocytes metabolized TCDD at a similar rate (0.20 and 0.18 pmol/hr/mg, respectively). In both species, TCDD and 3-MC pretreatments elevated the rate of TCDD metabolism by 5-6-fold, while PB pretreatment had no effect. isosafrole modestly increased (1.8-2.5-fold) TCDD metabolism in ...
The lnfluence of mlcrosomal and nuclear aryl hydrocarbon hydroxylase (AHH) actlvlty on the covalent blndlng of [G·3H]benzo(a )pyrene to rat llver DNA was evaluated in viWJ. lnductlon of mlcrosomal AHH was obtalned alter phenobarbltal treatment (160% of control), whlch also lncreased DNA blndlng to 190%, but left the nuclear actlvlty unchanged. Nuclear AHH was lnduced wlth dleldrln (150%), and the blndlng was decreased to 75%, whereaa the mlcrosomal AHH was at control Ievei. The lncreaslng effect of mlcrosomal AHH lnductlon as weil as the decreaslng effect of nuclear AHH lnductlon on the blndlng was shown clearly when the data of the Individual rata were uaed to solve the equatlon Binding = e•(mlcroeomal AHH) + b•(nuclear AHH) + c Multiple linear regresslon analysls wlth the data from 10 anlmala reaulted ln positive valuea for a and c, a negative value for b, and a good multiple correlatlon coefflclent of r = 0.974. Pretreatment wlth 3-methylcholanthrene ln· duced mlcrosomal AHH to 380% of ...
September 2020. In This Edition Articles Fundamental Aspects - Analysis and Identification of Mezcal and Tequila Aromas by Ambient Ionisation MS, GC-MS, and GCxGC-MS - Analysis of Polynuclear Aromatic Hy.... ...
September 2020. In This Edition Articles Fundamental Aspects - Analysis and Identification of Mezcal and Tequila Aromas by Ambient Ionisation MS, GC-MS, and GCxGC-MS - Analysis of Polynuclear Aromatic Hy.... ...
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Method of biolistic transformation was used for genetic improvement of commercial barley cultivars (Oksamitoviy, Vodogray and Getman). The plasmid pHLFTuBA was used for particle bombardment that consists of the hLF gene under the control of the barley glutelin B-1 promoter and a selectable marker gene, α-tubulin conferring resistance to trifluralin (dinitroanilinr herbicide). Preliminary screening of different trifluralin concentration range from 0,1 to 30 μM was tested for determination of effective selective agent concentration. Two transgenic barley line of genotype Oksamitiviy and transgenic callus line of cultivar Getman were obtained after selection on 10 μM of trifluralin. To confirm the transgenic nature of regenerated plants, the PCR analysis was carried out. The 734bp length fragment of hLF gene was amplified from both regenerated plants.. ...
GC Application #16187: Polynuclear Aromatic Hydrocarbons (PAHs): US and EU Analytes on ZB-MR1. Column used: Zebron™ ZB-MultiResidue™-1, GC Cap. Column 30 m x 0.25 mm x 0.25 µm, Ea Part#: 7HG-G016-11
GC Application #15560: Polynuclear Aromatic Hydrocarbons (PAHs) on ZB-5MS. Column used: Zebron™ ZB-5MS, GC Cap. Column 20 m x 0.18 mm x 0.18 µm, Ea Part#: 7FD-G010-08
Concomitant exposures to arsenic and polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (BaP) are widespread. While BaP acts by binding to and inducing mutations in critical sites on DNA, the mechanism(s) of arsenic carcinogenesis remains unknown. Data from epidemiological studies of arsenic copper smelter workers and arsenic ingestion in drinking water suggest a positive interaction f
Chan, J T. and Black, H S., Skin carcinogenesis. Cholesterol-5alpha, 6alpha-epoxide hydrase activity in mouse skin irradiated with ultraviolet light. (1974). Subject Strain Bibliography 1974. 1966 ...
US EPA PC Code ); 001 (PDP Code); 045101 (US EPA PC Code Text ); 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-(1a,4a,4ab,5a,8a,8ab)-1,4:5,8-dimethanonaphthalene; 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-exo-5,8-dimethanonaphthalene; 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1.alpha.,4.alpha.,4a.beta.,5.alpha.,8.alpha.,8; 309-00-2 (CAS number); 309002; 309002 (CAS number without hyphens); 9 (CA DPR Chem Code) ); Aldocit; Aldrex; Aldrin; ALDRIN (CA DPR Chem Code Text ); Aldrin [1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-(1.alpha.,4.alpha.,4a.beta.,5.alpha.,8.al; Aldrin/Dieldrin; Aldrine; Compound 118; Drinox; Eldrin; ENT-15949; Hexachlorohexahydro-endo, exo-dimethanonaphthalene; HHDM; HHDN; HHPN; Kortofin; Octalene; OMS 194; OMS-194; SD 2794; Seedrin; Tatuzinho; ...
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... aniline hydroxylase MeSH D12.776.422.220.453.040.110 - benzopyrene hydroxylase MeSH D12.776.422.220.453.040.332 - cytochrome p- ... steroid 11-beta-hydroxylase MeSH D12.776.422.220.453.915.730 - steroid 12-alpha-hydroxylase MeSH D12.776.422.220.453.915.737 - ... steroid 16-alpha-hydroxylase MeSH D12.776.422.220.453.915.748 - steroid 17-alpha-hydroxylase MeSH D12.776.422.220.453.915.760 ... cholesterol 7 alpha-hydroxylase MeSH D12.776.422.220.453.915.212 - cholesterol side-chain cleavage enzyme MeSH D12.776.422.220. ...
... aryl hydrocarbon hydroxylases MeSH D08.244.453.040.050 - aniline hydroxylase MeSH D08.244.453.040.110 - benzopyrene hydroxylase ... aniline hydroxylase MeSH D08.811.682.690.708.170.040.110 - benzopyrene hydroxylase MeSH D08.811.682.690.708.170.040.332 - ... steroid 11-beta-hydroxylase MeSH D08.244.453.915.730 - steroid 12-alpha-hydroxylase MeSH D08.244.453.915.737 - steroid 16-alpha ... hydroxylase MeSH D08.244.453.915.748 - steroid 17-alpha-hydroxylase MeSH D08.244.453.915.760 - steroid 21-hydroxylase MeSH ...
The 2014 Ju-Jitsu World Championship were the 12th edition of the Ju-Jitsu World Championships, and were held in Paris, France from November 28 to November 30, 2014. 28.11.2014 - Men's and Women's Fighting System, Men's and Women's Jiu-Jitsu (ne-waza), Men's Duo System - Classic 29.11.2014 - Men's and Women's Fighting System, Men's and Women's Jiu-Jitsu (ne-waza), Women's Duo System - Classic 30.11.2014 - Men's Jiu-Jitsu (ne-waza), Mixed Duo System - Classic, Team event Vincent MATCZAK (2014-09-30). "4TH INVITAION TO WORLD CHAMPIONSHIP 2014" (PDF). Retrieved 2019-11-28.[dead link] Online results Official results (PDF) Mixed team event results (PDF) (All articles with dead external links, Articles with dead external links from April 2022, Ju-Jitsu World Championships, 2014 in French sport ...
Bolley L. "Bo" Johnson (born November 15, 1951) is an American politician from the state of Florida. A member of the Democratic Party, Johnson was a member of the Florida House of Representatives, and served as the Speaker of the Florida House of Representatives. Johnson is from Milton, Florida. His father and grandfather served as county commissioners for Santa Rosa County, Florida. Johnson graduated from Milton High School, and became the first member of his family to attend college. He received his bachelor's degree from Florida State University. Johnson volunteered for Mallory Horne when Horne served as the president of the Florida Senate. At the age of 22, Johnson met Lawton Chiles, then a member of the United States Senate, who hired him as a legislative aide in 1973. Johnson was elected to the Florida House of Representatives, representing the 4th district from November 7, 1978 to November 3, 1992. He also served the 1st district from November 3, 1992 to November 8, 1994. He became the ...
... may refer to: Don't Say No (Billy Squier album), a 1981 album by American rock singer Billy Squier, and its title track Don't Say No (Seohyun EP), a 2016 extended play by South Korean pop singer Seohyun, and its title track "Don't Say No" (Tom Tom Club song), from the 1988 album Boom Boom Chi Boom Boom "Don't Say No", by Robbie Williams from the 2005 album Intensive Care "Don't Say No Tonight", a 1985 single by Eugene Wilde This disambiguation page lists articles associated with the title Don't Say No. If an internal link led you here, you may wish to change the link to point directly to the intended article. (Disambiguation pages with short descriptions, Short description is different from Wikidata, All article disambiguation pages, All disambiguation pages, Disambiguation pages ...
The Dewoitine 37 was the first of a family of 1930s French-built monoplane fighter aircraft. The D.37 was a single-seat aircraft of conventional configuration. Its fixed landing gear used a tailskid. The open cockpit was located slightly aft of the parasol wing. The radial engine allowed for a comparatively wide fuselage and cockpit. Design of this machine was by SAF-Avions Dewoitine but owing to over work at that companies plant at the time, manufacture of the D.37/01 was transferred to Lioré et Olivier. They were high-wing monoplanes of all-metal construction with valve head blisters on their engine cowlings. The first prototype flew in October 1931. Flight testing resulted in the need for multiple revisions in both engine and airframe, so it was February 1934 before the second prototype flew. Its performance prompted the French government to order for 28 for the Armée de l'Air and Aéronavale. The Lithuanian government ordered 14 that remained in service with their Air Force until 1936, ...
The Noor-ul-Ain (Persian: نور العين, lit. 'the light of the eye') is one of the largest pink diamonds in the world, and the centre piece of the tiara of the same name. The diamond is believed to have been recovered from the mines of Golconda, Hyderabad in India. It was first in possession with the nizam Abul Hasan Qutb Shah, later it was given as a peace offering to the Mughal emperor Aurangazeb when he defeated him in a siege. It was brought into the Iranian Imperial collection after the Persian king Nader Shah Afshar looted Delhi in the 18th century.[citation needed] The Noor-ul-Ain is believed to have once formed part of an even larger gem called the Great Table diamond. That larger diamond is thought to have been cut in two, with one section becoming the Noor-ul-Ain and the other the Daria-i-Noor diamond. Both of these pieces are currently part of the Iranian Crown Jewels. The Noor-ul-Ain is the principal diamond mounted in a tiara of the same name made for Iranian Empress Farah ...
The Benoist Land Tractor Type XII was one of the first enclosed cockpit, tractor configuration aircraft built. Benoist used "Model XII" to several aircraft that shared the same basic engine and wing design, but differed in fuselage and control surfaces. The Type XII was a tractor-engined conversion of the model XII headless pusher aircraft that resembled the Curtiss pusher aircraft. Demonstration pilots used Benoist aircraft to demonstrate the first parachute jumps, and the tractor configuration was considered much more suitable for the task. The first example named the "Military Plane" had a small box frame covered fuselage that left the occupants mostly exposed to the wind. The later model XII "Cross Country Plane" had a full fuselage that occupants sat inside of. The first tractor biplane used a wooden fuselage with a small seat on top. The wings were covered with a Goodyear rubberized cloth. The first model XII was built in the spring of 1912. On 1 March 1912, Albert Berry used a headless ...
... (also known as Yalmotx in Qʼanjobʼal) is a town, with a population of 17,166 (2018 census), and a municipality in the Guatemalan department of Huehuetenango. It is situated at 1450 metres above sea level. It covers a terrain of 1,174 km². The annual festival is April 29-May 4. Barillas has a tropical rainforest climate (Af) with heavy to very heavy rainfall year-round and extremely heavy rainfall from June to August. Citypopulation.de Population of departments and municipalities in Guatemala Citypopulation.de Population of cities & towns in Guatemala "Climate: Barillas". Climate-Data.org. Retrieved July 26, 2020. Muni in Spanish Website of Santa Cruz Barillas Coordinates: 15°48′05″N 91°18′45″W / 15.8014°N 91.3125°W / 15.8014; -91.3125 v t e (Articles with short description, Short description is different from Wikidata, Pages using infobox settlement with no coordinates, Articles containing Q'anjob'al-language text, Coordinates on Wikidata, ...
Maria Margaret La Primaudaye Pollen (10 April 1838 - c. 1919), known as Minnie, was a decorative arts collector. As Mrs John Hungerford Pollen, she became known during the early-twentieth century as an authority on the history of textiles, publishing Seven Centuries of Lace in 1908. Maria Margaret La Primaudaye was born into a Huguenot family on 10 April 1838, the third child of the Revd Charles John La Primaudaye, a descendant of Pierre de La Primaudaye. She was educated in Italy. Her family converted to Catholicism in 1851, and it was in Rome that her father met another recent English convert, John Hungerford Pollen, previously an Anglican priest and a decorative artist. She became engaged to Pollen, who was then seventeen years her senior, in the summer of 1854, and was married in the church of Woodchester monastery, near Stroud, Gloucester, on 18 September 1855. The Pollens initially settled in Dublin, where John Hungerford Pollen had been offered the professorship of fine arts at the ...
Ronald Robert Fogleman (born January 27, 1942) is a retired United States Air Force general who served as the 15th Chief of Staff of the Air Force from 1994 to 1997 and as Commanding General of the United States Transportation Command from 1992 to 1994. A 1963 graduate from the United States Air Force Academy, he holds a master's degree in military history and political science from Duke University. A command pilot and a parachutist, he amassed more than 6,800 flying hours in fighter, transport, tanker and rotary wing aircraft. He flew 315 combat missions and logged 806 hours of combat flying in fighter aircraft. Eighty of his missions during the Vietnam War were as a "Misty FAC" in the F-100F Super Sabre at Phù Cát Air Base, South Vietnam between 25 December 1968 and 23 April 1969. Fogleman was shot down in Vietnam in 1968, while piloting an F-100. He was rescued by clinging to an AH-1 Cobra attack helicopter that landed at the crash site. In early assignments he instructed student pilots, ...
Peachtree Street" is a 1950 song co-written and recorded by Frank Sinatra in a duet with Rosemary Clooney. The song was released as a Columbia Records single. Frank Sinatra co-wrote the song with Leni Mason and Jimmy Saunders. Mason composed the music while Sinatra and Saunders wrote the lyrics. The song was arranged by George Siravo The song was released as an A side Columbia 10" 78 single, Catalog Number 38853, Matrix Number CO-43100-1 and as a 7" 33, 1-669. The B side was the re-issued "This Is the Night." Neither of the songs charted. The subject of the song is a stroll down the street in Atlanta, Georgia of the same name. Sinatra originally intended Dinah Shore to sing the duet with him. When Shore declined, Clooney was asked. The song was recorded on April 8, 1950. The song features spoken asides by Sinatra and Clooney. Rosemary Clooney asks: "Say, Frank, you wanna take a walk?" Frank Sinatra replies: "Sure, sweetie, just pick a street." He noted how there were no peach trees on the ...
... is a painting by American illustrator Norman Rockwell that depicts a Boy Scout in full uniform standing in front of a waving American flag. It was originally created by Rockwell in 1942 for the 1944 Brown & Bigelow Boy Scout Calendar. The model, Bob Hamilton, won a contest to be in the painting and personally delivered a print to the Vice President of the United States at the time, Henry A. Wallace. The painting was created to encourage Scouts to participate in the war effort during World War II. The name of the painting, We, Too, Have a Job to Do, comes from a slogan that the Boy Scouts of America used in 1942 to rally scouts to support the troops by collecting metal and planting victory gardens. The model, Bob Hamilton, won a contest with his local council in Albany, New York, to be depicted in the painting. He traveled to Rockwell's studio in Arlington, Vermont, to model for Rockwell. Since Hamilton was a scout, the uniform shown in the painting was his, unlike some ...
At least 33[failed verification] people were killed by a fuel tanker explosion in Tleil, Akkar District, Lebanon on 15 August 2021. The disaster was reportedly exacerbated by the ongoing Lebanese liquidity crisis; in which the Lebanese pound has plummeted and fuel has been in short supply. The survivors were evacuated by the Lebanese Red Cross. An investigation is underway. The fuel tanker had been confiscated by the Lebanese Armed Forces from black marketeers, the fuel was then distributed/taken by the locals. The son of the man whose land the fuel tanker was located on, was later arrested, accused of deliberately causing the explosion. Agencies (2021-08-15). "At least 20 killed and 79 injured in fuel tank explosion in Lebanon". the Guardian. Retrieved 2021-08-15. "Lebanon fuel explosion kills 22 and injures dozens more". The Independent. 2021-08-15. Archived from the original on 2021-08-15. Retrieved 2021-08-15. "Lebanon: At least 20 dead and dozens injured after fuel tank explodes as ...
The Straubing Tigers are a professional men's ice hockey team, based in Straubing, Germany, that competes in the Deutsche Eishockey Liga. Straubing plays its home games at the Eisstadion am Pulverturm, which has a capacity of 5,800 spectators. Promoted to the DEL in 2006, and operating with one of the league's smallest budgets, the team could finish no better than twelfth before the 2011-12 DEL season, when it reached the semi-finals of the playoffs. Their greatest success so far is the qualification for the season 2020-21 of the Champions Hockey League. In 1941, the then 14-year-old Max Pielmaier and his friends Max Pellkofer and Harry Poiger founded the first hockey team in Straubing. The first official game took place on the first of February 1942 in Hof and was lost by a score of 0:1. In the following year there were several games against other Bavarian teams. The game against Landshut on 31 January. 1943 was the last game during the second World War, because the young players also had to ...
Leina is a village in Saaremaa Parish, Saare County in western Estonia. Before the administrative reform in 2017, the village was in Pihtla Parish. "Lisa. Asustusüksuste nimistu" (PDF). haldusreform.fin.ee (in Estonian). Rahandusministeerium. Retrieved 5 December 2017. "Saaremaa külad endiste valdade piires". www.saaremaa.ee (in Estonian). Archived from the original on 3 December 2017. Retrieved 5 December 2017. Coordinates: 58°17′10″N 22°46′26″E / 58.28611°N 22.77389°E / 58.28611; 22.77389 v t e (CS1 Estonian-language sources (et), Articles with short description, Short description is different from Wikidata, Pages using infobox settlement with no map, Pages using infobox settlement with no coordinates, Saaremaa Parish, Coordinates on Wikidata, Villages in Saare County, All stub articles, Saare County geography stubs ...
A sestiere (plural: sestieri) is a subdivision of certain Italian towns and cities. The word is from sesto ('sixth'), so it is thus used only for towns divided into six districts. The best-known example is the sestieri of Venice, but Ascoli Piceno, Genoa, Milan and Rapallo, for example, were also divided into sestieri. The medieval Lordship of Negroponte, on the island of Euboea, was also at times divided into six districts, each with a separate ruler, through the arbitration of Venice, which were known as sestieri. The island of Crete, a Venetian colony (the "Kingdom of Candia") from the Fourth Crusade, was also divided into six parts, named after the sestieri of Venice herself, while the capital Candia retained the status of a comune of Venice. The island of Burano north of Venice is also subdivided into sestieri. A variation of the word is occasionally found: the comune of Leonessa, for example, is divided into sesti or sixths. Other Italian towns with fewer than six official districts are ...
The Island Image is a Chesapeake Bay log canoe, built in 1885 at Elliot's Island, Maryland, by Herman Jones and Isaac Moore. She is 29'-8½" long with a beam of 5-10¼", and has a straight, raking stem and a sharp stern. It is privately owned, and races under No. 17. She one of the last 22 surviving traditional Chesapeake Bay racing log canoes that carry on a tradition of racing on the Eastern Shore of Maryland that has existed since the 1840s. She is located at Chestertown, Kent County, Maryland. She was listed on the National Register of Historic Places in 1985. "National Register Information System". National Register of Historic Places. National Park Service. April 15, 2008. "Maryland Historical Trust". ISLAND IMAGE (log canoe). Maryland Historical Trust. 2008-06-14. "Island Image #17 , CBLCSA". Island Image. Chesapeake Bay Log Sailing Canoe Association. 2010-07-24. Archived from the original on 2011-07-08. Retrieved 2010-07-29. ISLAND IMAGE (log canoe), Kent County, including photo in 1984, ...
... (Persian: دهستان بردخون) is a rural district (dehestan) in the Bord Khun District of Deyr County, Bushehr Province, Iran. At the 2006 census, its population was 1,115, in 234 families. The rural district has 14 villages. "Census of the Islamic Republic of Iran, 1385 (2006)" (Excel). Statistical Center of Iran. Archived from the original on 2011-11-11. Coordinates: 27°58′N 51°32′E / 27.967°N 51.533°E / 27.967; 51.533 v t e (Articles with short description, Short description matches Wikidata, Pages using infobox settlement with no map, Pages using infobox settlement with no coordinates, Articles containing Persian-language text, Coordinates on Wikidata, Rural Districts of Bushehr Province, Deyr County, All stub articles, Deyr County geography stubs ...
... is a disease of camels caused by the camelpox virus (CMPV) of the family Poxviridae, subfamily Chordopoxvirinae, and the genus Orthopoxvirus. It causes skin lesions and a generalized infection. Approximately 25% of young camels that become infected will die from the disease, while infection in older camels is generally more mild. Although rare, the infection may spread to the hands of those that work closely with camels. The camelpox virus that causes camelpox is an orthopoxvirus that is very closely related to the variola virus that causes smallpox. It is a large, brick-shaped, enveloped virus that ranges in size from 265-295 nm. The viral genetic material is contained in a linear double-stranded DNA consisting of 202,182 tightly packed base pairs. The DNA is encased in the viral core. Two lateral bodies are found outside the viral core, and are believed to hold the enzymes required for viral reproduction. The camelpox virus most often affects members of family Camelidae. However, ...
... s (/ˈfɛzənt/ FEH-zənt) are birds of several genera within the family Phasianidae in the order Galliformes. Although they can be found all over the world in introduced (and captive) populations, the pheasant genera native range is restricted to Eurasia. The classification "pheasant" is paraphyletic, as birds referred to as pheasants are included within both the subfamilies Phasianinae and Pavoninae, and in many cases are more closely related to smaller phasianids, grouse, and turkey (formerly classified in Perdicinae, Tetraoninae, and Meleagridinae) than to other pheasants. Pheasants are characterised by strong sexual dimorphism, males being highly decorated with bright colours and adornments such as wattles. Males are usually larger than females and have longer tails. Males play no part in rearing the young. A pheasants call or cry can be recognised due to the fact it sounds like a rusty sink or valve being turned. Pheasants eat mostly seeds, grains, roots, and berries, while in the ...
Paul S. Mischel (born July 13, 1962) is an American physician-scientist whose laboratory has made pioneering discoveries in the pathogenesis of human cancer. He is currently a Professor and Vice Chair of Research for the Department of Pathology and Institute Scholar of ChEM-H, Stanford University. Mischel was elected into the American Society for Clinical Investigation (ASCI), serving as ASCI president in 2010/11. He was inducted into the Association of American Physicians, and was elected as a fellow of the American Association for the Advancement of Science. Mischel was born on July 13, 1962. After losing his father to cancer, he became committed to a career in cancer research. He attended the University of Pennsylvania and received his M.D. from Cornell University Medical College in 1991, graduating Alpha Omega Alpha. Mischel completed residency training in Anatomic Pathology and Neuropathology at UCLA, followed by post-doctoral research training with Louis Reichardt at HHMI-UCSF. Mischel ...
... is a moth of the family Sphingidae. It is known from highland forest in central Kenya and also in Zimbabwe. The length of the forewings is about 24 mm for males and 26 mm for females. It is similar to Temnora griseata griseata but the upperside of the head has a dark brown median longitudinal crest, the forewing apex and tornus are more acute and the outer margin is more deeply excavated below the apex. The forewing upperside ground colour is dark brown and the pattern of transverse lines is more contrasted. Temnora subapicalis subapicalis Temnora subapicalis hayesi Darge, 1975 (Rwanda) "CATE Creating a Taxonomic eScience - Sphingidae". Cate-sphingidae.org. Retrieved 2011-10-25.[permanent dead link] Carcasson, R. H. (1967). "Revised Catalogue of the African Sphingidae (Lepidoptera) with Descriptions of the East African species". Journal of the East Africa Natural History Society and National Museum. 26 (3): 1-173 - via Biodiversity Heritage Library. v t e (All articles with ...
... is a name under which singer-songwriter Dan Michaelson records and performs. They have previously stated that they are inspired by Leonard Cohen, Johnny Cash, Etta James and Dusty Springfield. Following the release of Blindspot in 2013 and Sudden Fiction in 2011, the band released Distance in August 2014. Memory was released in May 2016. Albums Singles Simpson, Dave (5 May 2016). "Dan Michaelson and the Coastguards: Memory review - magical, melancholy songs". Theguardian.com. Retrieved 21 October 2020. Dan Michaelson and The Coastguards official site Dan Michaelson and The Coastguards myspace page The state51 Conspiracy official site Official YouTube (Use dmy dates from June 2020, Use British English from June 2016, Articles needing additional references from October 2016, All articles needing additional references, Articles with hCards, Pages using infobox musical artist with associated acts, Articles with ISNI identifiers, Articles with MusicBrainz ...
The Edmonton Drillers were a North American Soccer League team that played both outdoors and indoors from 1979 to 1982, at the peak of the league's success. The team was brought to Edmonton by local entrepreneur and Edmonton Oilers owner Peter Pocklington, after witnessing the strong support for Brian Rice's Edmonton Black Gold team in 1978. Previous to playing in Edmonton, the team was known as the Oakland Stompers, Hartford Bicentennials and Connecticut Bicentennials. Joe Petrone was the Drillers general manager for their entire existence. The Drillers were coached in 1979 and 1980 by Hans Kraay, who brought a number of players with him from the Netherlands. After Kraay, Timo Liekoski took over as coach in 1981, while Patrone would serve as the team's final caretaker coach until the team folded at the end of the 1982 season. During the outdoor season, the Drillers played their home games at Commonwealth Stadium, but dwindling crowds during the final year saw the team move to much older and ...
... is a compilation album featuring songs from various artists in all genres of popular music. The songs were picked from among some of the most popular during the autumn of 2006 in Australia. The album was released on 26 March 2006. Mariah Carey - "Don't Forget About Us" (3:54) Chris Brown - "Run It!" (3:14) Gwen Stefani - "Luxurious" (4:26) TV Rock - "Flaunt It" (3:29) Rogue Traders - "Watching You" (3:29) Lee Harding - "Wasabi" (3:00) The Black Eyed Peas - "My Humps" (4:12) The Pussycat Dolls - "Stickwitu" (3:29) Sugababes - "Push the Button" (3:38) Kelly Clarkson - "Walk Away" (3:08) Rihanna - "If It's Lovin' that You Want" (3:28) Daddy Yankee - "Gasolina" (3:15) Nickelback - "Far Away" (3:59) Bernard Fanning - "Wish You Well" (2:31) Pete Murray - "Class A" (3:05) Shannon Noll - "Lift" (3:57) Lindsay Lohan - "Confessions of a Broken Heart (Daughter to Father)" (3:43) Kate DeAraugo - "Maybe Tonight" (3:38) Backstreet Boys - "I Still..." (3:49) Meck featuring Leo ...
Kızılpınar Atatürk is a neighborhood in Çerkezköy district of Tekirdağ Province, Turkey. At 41°16′N 27°58′E / 41.267°N 27.967°E / 41.267; 27.967 it is almost merged to Çerkezköy. Distance to Tekirdağ is about 55 kilometres (34 mi). The population of Kızılpınar Atatürk is 22,966 "Turkstat". Turkish Statistical Institute. Retrieved 4 February 2021. "Turkstat". Turkish Statistical Institute. Retrieved 4 February 2021. Tekirdağ Governor's Official Website Metropolitan Municipality of Tekirdağ District municipality's Official Website v t e (Pages with non-numeric formatnum arguments, Articles with short description, Short description matches Wikidata, Articles needing additional references from March 2020, All articles needing additional references, Coordinates on Wikidata, AC with 0 elements, Populated places in Tekirdağ Province, Towns in Turkey, Çerkezköy District, Things named after Mustafa Kemal Atatürk, All stub articles, Marmara Region geography stubs ...
... is an anamorph species of the genus Penicillium. MycoBank Straininfo of Penicillium murcianum UniProt ATCC Ramírez, C.; Martínez, A. T. (1981). "Seven new species of Penicillium and a new variety of Penicillium novae-caledoniae Smith". Mycopathologia. 74: 35. doi:10.1007/BF00441440. Ramírez, C.; Martínez, A. T. (1981). "Seven new species of Penicillium and a new variety of Penicillium novae-caledoniae Smith". Mycopathologia. 74: 35. doi:10.1007/BF00441440. Robert Samson (2013). Advances in Penicillium and Aspergillus Systematics. Springer Science & Business Media. ISBN 147571856X. (Articles with short description, Short description matches Wikidata, Articles with 'species' microformats, Penicillium, Fungi described in 1981 ...
... (born 17 March 1991 in Salisbury) is a British canoe slalom athlete who competed between 2003 and 2014. His results include a Silver Medal at the Junior European Championships in 2009 (team-event), 15th at the ICF Senior Pre-world Championships in 2010, and a UK ranking of 5th. Coombs also competed for Nottingham Trent University and took 3 golds in the 2011 BUCS Canoe Slalom Championships. Salisbury Canoe Club. Retrieved 2011-05-14 GB Canoe Slalom Team 2011 Retrieved 2011-05-14 ICF Canoe Slalom World Ranking 2010 Retrieved 2011-05-14 "Young talent is being nurtured (From Salisbury Journal)". Salisburyjournal.co.uk. 20 January 2011. Retrieved 13 May 2011. UK ranking "Slalom UK - The website of Canoe Slalom in Britain". Canoeslalom.co.uk. Archived from the original on 27 October 2011. Retrieved 13 May 2011. 2011 BUCS Canoe Slalom Championships "Slalom Championships - British Universities & Colleges Sport". Bucs.org.uk. 1 March 2011. Retrieved 13 May 2011. Official Website (Articles ...
... (c. 1950 - 23 April 2020) was an Indian politician and the former member of the Jammu and Kashmir Legislative Assembly. A member of Jammu and Kashmir National Conference, he started his political career from Hazratbal constituency in 1987 and later, represented Sonawar constituency in 1996 and subsequently served as political adviser to the then chief minister, Farooq Abdullah. Prior to his participation in assembly elections, he served as councillor of the Srinagar Municipal Corporation. In 2002, he was again elected from the Sonawari constituency. In 2009, Farooq Abdullah was elected as the member of parliament, making the constituency become vacant in 2009 and he retained his position again via by-election. "NC leader Yasin Shah dies". Business Standard. Press Trust of India. 23 April 2020. "NC Leader Yasin Shah Is No More". Kashmir Life. 23 April 2020. "NC leader Yasin Shah dies". outlookindia.com. v t e (Articles with short description, Short description is different ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene hydroxylase - Concept préféré Concept UI. M0002368. Terme préféré. Benzopyrene hydroxylase Synonymes. Benzo(a) ... Benzo(a)pyrène hydroxylase. Benzo(a)pyrène monooxygénase. Benzopyrène hydroxylase. Code(s) darborescence:. D08.244.453.005.110 ... A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene ... Benzopyrene hydroxylase Descripteur en anglais: Benzopyrene Hydroxylase Descripteur en espagnol: Benzopireno Hidroxilasa ...
Aryl Hydrocarbon Hydroxylases --biosynthesis. en_US. dc.subject.mesh. Benzopyrene Hydroxylase --biosynthesis. en_US. ... Induction of benzo(a)pyrene hydroxylase & cytochrome P-448 in hepatic microsomes by jute batching oil. Indian Journal of ... Induction of benzo(a)pyrene hydroxylase & cytochrome P-448 in hepatic microsomes by jute batching oil.. en_US. ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene Hydroxylase Medicine & Life Sciences 44% * Chlorodiphenyl (54% Chlorine) Medicine & Life Sciences 40% ... hydroxylase (or aryl hydrocarbon hydroxylase, AHH) activities, the cytochrome b5 content and the relative peak intensities and ... hydroxylase (or aryl hydrocarbon hydroxylase, AHH) activities, the cytochrome b5 content and the relative peak intensities and ... hydroxylase (or aryl hydrocarbon hydroxylase, AHH) activities, the cytochrome b5 content and the relative peak intensities and ...
Cholesterol 25-hydroxylase (CH25H) is a conserved interferon-stimulated gene, which converts cholesterol to a soluble antiviral ... 4-benzopyrene content of this hotpot oil exceeded the EU standard after boiling for 7 h, the increase in the amount of harmful ...
Properties of Benzopyrene-DNA Complexes Investigated by Fluorescence and Triplet Flash Photolysis Techniques. Geacintov, N. E. ... Temporal effects of fornix transection on brain tryptophan hydroxylase activity and plasma corticosterone levels. Azmitia, E. C ...
Bile others serve mutated from somite via two receptors - a estrogen-related viral space editing night 7-alpha-hydroxylase( ... and More 2008 benzopyrene) participate SMAD4 and these acids are consistent G annotations including in wrapping compartments( ... CYP7A1), and an repulsive subunit transporting acute 7-alpha-hydroxylase( CYP7B1). efforts in CYP7B1 can be such complex 5A( ...
The control used in this experiment was cells stimulated with 2.5 µM benzopyrene for 12-18 h and exposed to 1:19 v/v cigarette ... CYP4F3 (leukotriene-B(4)omega-hydroxylase 2), GCLC (glutamate-cysteine ligase catalytic subunit), SLC7A11 (solute carrier ... The presence of RE in the filter lead to considerably reduced benzopyrene levels and associated DNA adduct formation [28] ( ... TNFα (tumor necrosis factor), PARP (poly ADP ribose polymerase), BP (benzopyrene), Fos (FBJ murine osteogenic sarcoma virus), ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
12-alpha-Hydroxylase use Steroid 12-alpha-Hydroxylase 12-HETE use 12-Hydroxy-5.8,10,14-eicosatetraenoic Acid ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
25-Hydroxycholecalciferol 1-Hydroxylase use 25-Hydroxyvitamin D3 1-alpha-Hydroxylase. 25-Hydroxycholecalciferol use Calcifediol ... 3,4-Benzopyrene use Benzo(a)pyrene. 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
Vainio S, Genest PA, ter Riet B, van Luenen H, Borst P (2009). "Evidence that J-binding protein 2 is a thymidine hydroxylase ... Benzopyrene DNA adduct 1JDG.png (c) Zephyris, CC-BY-SA-3.0 Eukaryote DNA-en.svg Forfatter/Opretter: Sponk, Tryphon, Magnus ...
MeSH Terms: Animals; Benzo(a)pyrene; Benzoflavones/pharmacology*; Benzopyrene Hydroxylase/metabolism; Benzopyrenes/metabolism; ...
Substrate-induced synthesis and other properties of benzopyrene hydroxylase in rat liver. J Biol Chem 1957;228:753-66. ... comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. Cancer Res 1992;52:6248-53. ...
... such as benzopyrene hydroxylases) in the small bowel may help explain the rarity of small bowel malignancies. Certain groups of ...
... inhibition of benzopyrene hydroxylase (EC 1.14.14.1), and increased parahydroxylation of aniline (Akin & Norred, 1978). 8.3.5. ...
Aryl Hydrocarbon Hydroxylases [D08.244.453.005] * Aniline Hydroxylase [D08.244.453.005.050] * Benzopyrene Hydroxylase [D08.244. ... Benzopyrene-3-Monooxygenase Registry Number. EC 1.14.14.-. Previous Indexing. Benzopyrenes (1968-1974). Hydroxylases (1968-1974 ... Benzopyrene Hydroxylase Preferred Term Term UI T004573. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Benzopyrene Hydroxylase Preferred Concept UI. M0002368. Registry Number. EC 1.14.14.-. Scope Note. A drug-metabolizing, ...
Aryl Hydrocarbon Hydroxylases [D08.244.453.005] * Aniline Hydroxylase [D08.244.453.005.050] * Benzopyrene Hydroxylase [D08.244. ... Benzopyrene-3-Monooxygenase Registry Number. EC 1.14.14.-. Previous Indexing. Benzopyrenes (1968-1974). Hydroxylases (1968-1974 ... Benzopyrene Hydroxylase Preferred Term Term UI T004573. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Benzopyrene Hydroxylase Preferred Concept UI. M0002368. Registry Number. EC 1.14.14.-. Scope Note. A drug-metabolizing, ...
Benzopyrene Hydroxylase 18% * ethoxyresorufin 16% * Peroxides 13% * Cooking 13% * Cell Line 12% ...
Benzopyrene Hydroxylase 56% * Cell Culture Techniques 12% * Cytochrome P-450 CYP1A1 85% ... Dive into the research topics of PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O- ... PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat ...
... benzopyrene dihydrodiol benzopyrene dihydrodiols benzopyrene diol epoxide benzopyrene hydroxylase benzopyrene hydroxylases ... benzopyrene hydroxymethylase benzopyrenes benzopyrone benzo-pyrone benzopyrones benzo-pyrones benzopyrylium benzoquate ... D benzoporphyrins benzopurpurine benzopurpurines benzopyran benzopyranoperidine benzopyrans benzopyrene benzopyrene-7,8- ... arylformamidases arylhydrazone arylhydrazones arylhydrocarbon aryl hydrocarbon hydroxylase arylhydrocarbon hydroxylase ...
Benzopyrene Hydroxylase Medicine & Life Sciences 67% * 1-naphthol Medicine & Life Sciences 66% ... 2. The inhibitors comprised two groups: those inhibiting primarily benzo(a)-pyrene hydroxylase activity, and those inhibiting ... 2. The inhibitors comprised two groups: those inhibiting primarily benzo(a)-pyrene hydroxylase activity, and those inhibiting ... 2. The inhibitors comprised two groups: those inhibiting primarily benzo(a)-pyrene hydroxylase activity, and those inhibiting ...
Benzophenoneidum N0000007552 Benzophenones N0000007553 Benzopyrans N0000170043 Benzopyrene Hydroxylase N0000167358 Benzopyrenes ... Hydroxylase N0000170031 Steroid 17-alpha-Hydroxylase N0000170039 Steroid 21-Hydroxylase N0000170030 Steroid Hydroxylases ... Stem Cell Factor N0000171428 Sterigmatocystin N0000170037 Steroid 11-beta-Hydroxylase N0000170036 Steroid 12-alpha-Hydroxylase ... 25-Dihydroxyvitamin D 3 N0000168616 25-Hydroxyvitamin D 2 N0000170035 25-Hydroxyvitamin D3 1-alpha-Hydroxylase N0000166931 2H- ...
Aryl hydrocarbon hydroxylase is regularly induced by smoking. Benzopyrene hydroxylase and aminozao dye N-methylase were higher ... including benzopyrene (96), smokers are rendered tolerant to both the therapeutic and toxic effects of a wide variety of drugs ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
Benzopyrene Hydroxylase D8.586.682.420.170.40.110 D8.586.682.580.170.40.110 beta-MSH D12.644.360.75 D6.472.699.631.525.690. ... Replaced for 2003 by Steroid 21-Hydroxylase) Steroid Hydroxylases D8.586.682.420.783 D8.262.453.915 D8.586.682.580.170.915 ... D11.303.553.249 Aniline Hydroxylase D8.586.682.420.170.40.50 D8.586.682.580.170.40.50 Animal Testing Alternatives H1.770.644.67 ... G13.695 Phenylalanine Hydroxylase D8.586.682.420.601 D8.586.682.580.601 Philadelphia Chromosome G5.148.175.870.680 A11.284. ...
Benzopyrene Hydroxylase D8.244.453.40.110 D8.244.453.05.110 D8.811.682.690.708.170.40.110 D8.811.682.690.708.170.10.110 D12.776 ... Aniline Hydroxylase D8.244.453.40.50 D8.244.453.05.50 D8.811.682.690.708.170.40.50 D8.811.682.690.708.170.10.50 D12.776.422.220 ... Vitamin D3 24-Hydroxylase D8.244.453.978 D8.244.453.496.500 D8.811.682.690.708.170.957 D8.811.682.690.708.170.469.500 D12.776. ... Aryl Hydrocarbon Hydroxylases D8.244.453.40 D8.244.453.05 D8.811.682.690.708.170.40 D8.811.682.690.708.170.10 D12.776.422.220. ...
... benzopyrene dihydrodiol benzopyrene dihydrodiols benzopyrene diol epoxide benzopyrene hydroxylase benzopyrene hydroxylases ... benzopyrene hydroxymethylase benzopyrenes benzopyrone benzo-pyrone benzopyrones benzo-pyrones benzopyrylium benzoquate ... D benzoporphyrins benzopurpurine benzopurpurines benzopyran benzopyranoperidine benzopyrans benzopyrene benzopyrene-7,8- ... arylformamidases arylhydrazone arylhydrazones arylhydrocarbon aryl hydrocarbon hydroxylase arylhydrocarbon hydroxylase ...
Benzopyrene Hydroxylase Benzopyrenes TERM ... 25-Hydroxyvitamin D3 1-alpha-Hydroxylase 2H-Benzo(a)quinolizin- ... Cholesterol 24-Hydroxylase Cholesterol 7-alpha-Hydroxylase Cholesterol Ester Storage Disease Cholesterol Ester Transfer ... Dopamine beta-Hydroxylase Dopamine D2 Receptor Antagonists Dopamine Plasma Membrane Transport Proteins Dopamine Uptake ... Aniline Hydroxylase Aniline Mustard Anilino Naphthalenesulfonates Animal Assisted Therapy Animal Care Committees Animal ...
Benzopyrene exposure disrupts DNA methylation and growth dynamics in breast cancer cells. Toxicol Appl Pharmacol 216(3):458- ... comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. Cancer Res 52(22):6248-62531423269. Medline, ... DNA methylation analysis using CpG microarrays is impaired in benzopyrene exposed cells. Toxicol Appl Pharmacol 225(3):300- ...
Cholesterol 25-hydroxylase (CH25H) is a conserved interferon-stimulated gene, which converts cholesterol to a soluble antiviral ... 4-benzopyrene content of this hotpot oil exceeded the EU standard after boiling for 7 h, the increase in the amount of harmful ...
A Comparison of the Properties in vitro of Biphenyl 2- and 4-Hydroxylase in the Mesocarp from Avocado Pear ( Persea americana ... Effects of Preincubation in vitro with 3,4-Benzopyrene and Phenobarbital on the Drug-Metabolism Systems Present in the ...
A drug which is postulated to be an inhibitor of dopamine-β-hydroxylase, which catalyzes the conversion of dopamine into ... It has been noted in studies that a diet high in nitrates (processed foods), benzopyrenes (grilled foods), alcohol, red meat ...
The binding in vivo of the ultimate carcinogen, benzo pyrene 7,8,-diol,-9,10-epoxide, to various regions of the SV40 chromosome ... The second type of variant has low levels of basal and inducible aryl hydrocarbon hydroxylase activity. This class contains ... SU-10603 [7-chloro-3,4-dihydro-2-(3-pyridyl)naphthalen-1-(2H)one; a steroid 17 alpha-hydroxylase inhibitor] treatment of the ... These criteria appear unique for the 17 alpha-hydroxylase defect in the heterozygote. PMID- 6300163 TI - Human ovarian 17 beta- ...
Outcomes On the nontoxic dosages chemical substances owned by nicotine aromatic amines benzopyrene phenols aldehydes plus some ... Tryptophan Hydroxylase *Uncategorized *Urokinase-type Plasminogen Activator Recent Posts. * The pronounced decrease of the ... Consistently the TMC 278 consultant compounds belonging to nicotine aromatic amines benzopyrene phenols aldehydes and some ... and dose-dependently increased IL-8 levels in TMC 278 the culture supernatants of 16HBE cells among these compounds benzopyrene ...
Regulation of 24-hydroxylase activity in mouse skin fibroblasts by cholecalciferol derivatives, triamcinolone acetonide and a ... New insights into benzo[¿]pyrene osteotoxicity in zebrafish. Ecotoxicology and Environmental Safety, 226. https://doi.org/ ... An Oxygen Molecular Sensor, the HIF Prolyl 4-Hydroxylase, in the Marine Protist Perkinsus olseni. Protist, 159 (3): 355-368. ... Role in 24 hydroxylase enhancement. Hormone and Metabolic Research, 20 (6): 339-343. http://www.scopus.com/inward/record.url? ...
  • IMSEAR at SEARO: Induction of benzo(a)pyrene hydroxylase & cytochrome P-448 in hepatic microsomes by jute batching oil. (who.int)
  • A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. (bvsalud.org)
  • Outcomes On the nontoxic dosages chemical substances owned by nicotine aromatic amines benzopyrene phenols aldehydes plus some various other volatile organics dose-dependently elevated reporter gene appearance. (elegantindulgence.net)
  • Consistently the TMC 278 consultant compounds belonging to nicotine aromatic amines benzopyrene phenols aldehydes and some other volatile organics significantly and dose-dependently increased IL-8 levels in TMC 278 the culture supernatants of 16HBE cells among these compounds benzopyrene is a most potent stimulator for inducing IL-8 production. (elegantindulgence.net)
  • A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. (nih.gov)