Histiocytic Disorders, Malignant
Thymelaeaceae
Photoaffinity Labels
Toxicity Tests, Chronic
Clusiaceae
The mangosteen plant family (sometimes classified as Guttiferae; also known as Hypericaceae) of the order THEALES, subclass Dilleniidae, class Magnoliopsida. It includes trees and shrubs with resinous, sticky sap, usually with broad-ended, oblong, leathery leaves with a strong, central vein, flowers with many stamens.
Psidium
Sydnones
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
Acridones
Carcinogenicity Tests
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Glycosides
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Carbon-Carbon Ligases
Solid-phase microextraction and GC-ECD of benzophenones for detection of benzodiazepines in urine. (1/275)
Benzodiazepines are common drugs that cause intoxication. Benzodiazepines and their metabolites can be converted by hydrolysis in acid to the corresponding benzophenones, which are easier to be separated from matrices because of their hydrophobic properties. In this study, a new separation technique called solid-phase microextraction (SPME), which can integrate extraction, concentration, sampling and sample introduction into one single procedure, has been employed to extract the products of benzodiazepines from urine after acid hydrolysis. The extracts were determined by gas chromatography with electron-capture detection (GC-ECD). The hydrolysis conditions were optimized by a statistic orthogonal design. Factors influencing direct-immersion (DI)-SPME process were also checked and chosen experimentally. The method was evaluated with spiked human urine samples. The recoveries of nine benzodiazepines ranged from 1 to 25%, with the highest for oxazolam and the lowest for bromazepam. The calibration curves were linear from 10 to 500 ng/mL for oxazolam, haloxazolam, flunitrazepam, nimetazepam, and clonazepam and from 20 to 1000 ng/mL for the others except bromazepam. The detection limits were 2-20 ng/mL for most drugs tested. The intraday and interday coefficients of variation of the developed method were within 10 and 17%, respectively. In addition, the utility of the method was confirmed by determining two ingested benzodiazepines (flunitrazepam and oxazolam) in a volunteer's urine; urine flunitrazepam was still detectable 32 h after a therapeutic dose (1.2 mg) of the drug. Finally, the DI-SPME was compared with the conventional liquid-liquid extraction with regard to detection limits and extraction efficiency of the analytes. By DI-SPME, more amounts of analytes could be introduced into GC column than by conventional liquid-liquid extraction, and thus lower detection limits of the analytes were reached, although benzophenone recoveries by DI-SPME were rather low. (+info)Mechanism of regulation of hsp70 chaperones by DnaJ cochaperones. (2/275)
Hsp70 chaperones assist a large variety of protein folding processes within the entire lifespan of proteins. Central to these activities is the regulation of Hsp70 by DnaJ cochaperones. DnaJ stimulates Hsp70 to hydrolyze ATP, a key step that closes its substrate-binding cavity and thus allows stable binding of substrate. We show that DnaJ stimulates ATP hydrolysis by Escherichia coli Hsp70, DnaK, very efficiently to >1000-fold, but only if present at high (micromolar) concentration. In contrast, the chaperone activity of DnaK in luciferase refolding was maximal at several hundredfold lower concentration of DnaJ. However, DnaJ was capable of maximally stimulating the DnaK ATPase even at this low concentration, provided that protein substrate was present, indicating synergistic action of DnaJ and substrate. Peptide substrates were poorly effective in this synergistic action. DnaJ action required binding of protein substrates to the central hydrophobic pocket of the substrate-binding cavity of DnaK, as evidenced by the reduced ability of DnaJ to stimulate ATP hydrolysis by a DnaK mutant with defects in substrate binding. At high concentrations, DnaJ itself served as substrate for DnaK in a process considered to be unphysiological. Mutant analysis furthermore revealed that DnaJ-mediated stimulation of ATP hydrolysis requires communication between the ATPase and substrate-binding domains of DnaK. This mechanism thus allows DnaJ to tightly couple ATP hydrolysis by DnaK with substrate binding and to avoid jamming of the DnaK chaperone with peptides. It probably is conserved among Hsp70 family members and is proposed to account for their functional diversity. (+info)Comparison of the potassium channel openers, WAY-133537, ZD6169, and celikalim on isolated bladder tissue and In vivo bladder instability in rat. (3/275)
The effects of the ATP-dependent potassium channel agonists ZD6169, celikalim, and WAY-133537 on bladder contractile function were examined in vitro on isolated bladder strips and in vivo on spontaneous bladder contractions. All three compounds produced a concentration-dependent relaxation of isolated rat detrusor strips (IC50 values = 0.93, 0.03, and 0.09 microM, respectively for ZD6169, celikalim, and WAY-133537. Contractile inhibition by all three compounds was fully reversed by 6 microM glyburide. These compounds also effectively inhibited spontaneous bladder contractions in the rat hypertrophied bladder model of detrusor instability. We also examined the electrophysiological properties of WAY-133537 on isolated rat bladder detrusor myocytes. Myocytes had an average resting membrane potential of -40 mV. Under patch current-clamp conditions, WAY-133537 (0.3 and 1.0 microM, n = 4-5) produced a significant hyperpolarization of 21 and 26 mV, respectively. Hyperpolarization was reversed by the addition of 5 microM glyburide. In patch voltage-clamp studies, WAY-133537 (0.3 microM, n = 3) significantly increased outward current in response to both voltage step and ramp protocols consistent with activation of the ATP-dependent potassium channel. In the detrusor instability model, WAY-133537 and celikalim had similar oral potencies (ED50 = 0.13 and 0.3 mg/kg, respectively), whereas ZD6169 was less potent (ED50 = 2.4 mg/kg). The antihypertensive agent celikalim exerted effects on the bladder at doses that significantly reduced systemic blood pressure. In contrast, both WAY-133537 and ZD6169 inhibited bladder hyperactivity at doses that produced minimal changes in both mean arterial blood pressure and heart rate. These data suggest that both WAY-133537 and ZD6169 may be useful in the treatment of bladder instability at doses associated with minimal hemodynamic side effects. (+info)Guanosine triphosphatase stimulation of oncogenic Ras mutants. (4/275)
Interest in the guanosine triphosphatase (GTPase) reaction of Ras as a molecular drug target stems from the observation that, in a large number of human tumors, Ras is characteristically mutated at codons 12 or 61, more rarely 13. Impaired GTPase activity, even in the presence of GTPase activating proteins, has been found to be the biochemical reason behind the oncogenicity of most Gly12/Gln61 mutations, thus preventing Ras from being switched off. Therefore, these oncogenic Ras mutants remain constitutively activated and contribute to the neoplastic phenotype of tumor cells. Here, we show that the guanosine 5'-triphosphate (GTP) analogue diaminobenzophenone-phosphoroamidate-GTP (DABP-GTP) is hydrolyzed by wild-type Ras but more efficiently by frequently occurring oncogenic Ras mutants, to yield guanosine 5'-diphosphate-bound inactive Ras and DABP-Pi. The reaction is independent of the presence of Gln61 and is most dramatically enhanced with Gly12 mutants. Thus, the defective GTPase reaction of the oncogenic Ras mutants can be rescued by using DABP-GTP instead of GTP, arguing that the GTPase switch of Ras is not irreversibly damaged. An exocyclic aromatic amino group of DABP-GTP is critical for the reaction and bypasses the putative rate-limiting step of the intrinsic Ras GTPase reaction. The crystal structures of Ras-bound DABP-beta,gamma-imido-GTP show a disordered switch I and identify the Gly12/Gly13 region as the hydrophobic patch to accommodate the DABP-moiety. The biochemical and structural studies help to define the requirements for the design of anti-Ras drugs aimed at the blocked GTPase reaction. (+info)The binding site for an inhibitor of squalene:hopene cyclase determined using photoaffinity labeling and molecular modeling. (5/275)
BACKGROUND: The squalene:hopene cyclases (SHCs) are bacterial enzymes that convert squalene into hopanoids, a function analogous to the action of oxidosqualene cyclases (OSCs) in eukaryotic steroid and triterpenoid biosynthesis. We have identified the binding site for a selective, potent, photoactivatable inhibitor of an SHC. RESULTS: SHC from Alicyclobacillus acidocaldarius was specifically labeled by [3H]Ro48-8071, a benzophenone-containing hypocholesteremic drug. Edman degradation of a peptide fragment of covalently modified SHC confirmed that Ala44 was specifically modified. Molecular modeling, using X-ray-derived protein coordinates and a single point constraint for the inhibitor, suggested several geometries by which Ro48-8071 could occupy the active site. CONCLUSIONS: A covalent complex of a potent inhibitor with a squalene cyclase has been characterized. The amino acid modification and molecular modeling suggest that Ro48-8071 binds at the junction between the central cavity and substrate entry channel, therefore inhibiting access of the substrate to the active site. (+info)A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat. (6/275)
The discovery that peroxisome proliferator-activated receptor (PPAR)-gamma was the molecular target of the thiazolidinedione class of antidiabetic agents suggested a key role for PPAR-gamma in the regulation of carbohydrate and lipid metabolism. Through the use of high-throughput biochemical assays, GW1929, a novel N-aryl tyrosine activator of human PPAR-gamma, was identified. Chronic oral administration of GW1929 or troglitazone to Zucker diabetic fatty (ZDF) rats resulted in dose-dependent decreases in daily glucose, free fatty acid, and triglyceride exposure compared with pretreatment values, as well as significant decreases in glycosylated hemoglobin. Whole body insulin sensitivity, as determined by the euglycemic-hyperinsulinemic clamp technique, was significantly increased in treated animals. Comparison of the magnitude of glucose lowering as a function of serum drug concentrations showed that GW1929 was 2 orders of magnitude more potent than troglitazone in vivo. These data were consistent with the relative in vitro potencies of GW1929 and troglitazone. Isolated perfused pancreas studies performed at the end of the study confirmed that pancreata from vehicle-treated rats showed no increase in insulin secretion in response to a step change in glucose from 3 to 10 mmol/l. In contrast, pancreata from animals treated with GW1929 showed a first- and second-phase insulin secretion pattern. Consistent with the functional data from the perfusion experiments, animals treated with the PPAR-gamma agonist had more normal islet architecture with preserved insulin staining compared with vehicle-treated ZDF rats. This is the first demonstration of in vivo efficacy of a novel nonthiazolidinedione identified as a high-affinity ligand for human PPAR-gamma. The increased potency of GW1929 compared with troglitazone both in vitro and in vivo may translate into improved clinical efficacy when used as monotherapy in type 2 diabetic patients. In addition, the significant improvement in daily meal tolerance may impact cardiovascular risk factor management in these patients. (+info)Effects of ZD6169, a K(ATP) channel opener, on the micturition reflex in the rat. (7/275)
The effects of ZD6169, a new ATP-sensitive potassium channel opener, on reflex urinary bladder activity were evaluated in urethane-anesthetized female Wistar rats. Continuous transvesical slow infusion cystometrograms (0.04 ml/min) were performed in untreated, capsaicin-pretreated (125 mg/kg s.c., 4 days before experiments) and capsaicin vehicle-pretreated rats. Intravesical infusion of ZD6169 in concentrations of 6, 15, 30, and 300 nM for 2 h at each concentration increased the intercontraction interval and pressure threshold for voiding in a concentration-dependent manner in untreated and vehicle-pretreated rats but not in capsaicin-pretreated animals. The effects appeared within 30 min after administration. ZD6169 did not alter baseline bladder pressure, duration of contractions, or the peak pressure during voiding. Glibenclamide (20 mg/kg i.v.) reversed the effects of ZD6169 (30 nM). During transvesical cystometrograms performed at a fast rate (0.21 ml/min), ZD6169 in concentrations between 6 and 300 nM did not alter the intercontraction interval or pressure threshold for voiding. ZD6169 produced smaller and more variable effects during slow transurethral cystometrograms. Capsaicin, a C-fiber afferent neurotoxin, administered s.c. 4 days before the experiment, produced similar changes and also eliminated the effect of ZD6169. These data suggest that ZD6169 raises the threshold for activation of C-fiber mechanoreceptors in the bladder wall and thereby increases the bladder volume for inducing reflex voiding. (+info)Differential and selective inhibition of protein kinase A and protein kinase C in intact cells by balanol congeners. (8/275)
The fungal metabolite balanol is a potent inhibitor of protein kinase A (PKA) and protein kinase C (PKC) in vitro that acts by competing with ATP for binding (K(i) approximately 4 nM); congeners of balanol show specificity for PKA over PKC. We have characterized the effects of balanol and 10"-deoxybalanol in intact cells to determine whether these compounds cross the cell membrane and whether the potency and specificity noted in vitro are preserved in vivo. In neonatal rat myocytes and cultured A431 cells transiently transfected with a cyclic AMP response element-luciferase reporter construct, balanol inhibits the induction of luciferase activity by isoproterenol, indicating inhibition of PKA. Western analysis shows that both balanol and 10"-deoxybalanol reduce phosphorylation of cAMP response element-binding protein in isoproterenol-stimulated A431 cells; inhibition is concentration dependent with an IC(50) value of approximately 3 microM. Balanol, but not 10"-deoxybalanol, inhibits phosphorylation of the myristoylated alanine-rich C kinase substrate protein, a PKC substrate, in phorbol ester-stimulated A431 cells (IC(50) approximately 7 microM). Our data demonstrate that balanol is a potent inhibitor of PKA and PKC in several whole-cell systems and causes no obvious toxicity. In addition, balanol congeners inhibit PKA and PKC with the specificity and potency predicted by in vitro experiments. (+info)
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Dispersive triplet excitation transport in organic glasses<...
Benzophenone oxime
2-Hydroxy-4-(2-ethylhexyloxy)benzophenone
Intermolecular Reductive
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Thao md david associated with oxybenzone have interesting past
Abstracts
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CCCC 1984, Volume 49, Issue 1, Abstracts pp. 71-77 | Collection of Czechoslovak Chemical Communications
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Benzophenone
... is a widely used building block in organic chemistry, being the parent diarylketone. Benzophenone can be used as a ... Benzophenone is used as an additive in flavorings or perfumes for "sweet-woody-geranium-like notes." Benzophenone is produced ... In 2014, benzophenones were named Contact Allergen of the Year by the American Contact Dermatitis Society. Benzophenone is an ... Substituted benzophenones such as oxybenzone and dioxybenzone are used in many sunscreens. The use of benzophenone-derivatives ...
Benzophenone-n
Benzophenone-10 (mexenone, 2-hydroxy-4-methoxy-4'-methyl-benzophenone) Benzophenone-11 (benzophenone-2 and benzophenone-6) ... Benzophenone-3 (oxybenzone) Benzophenone-4 (sulisobenzone) Benzophenone-5 (sulisobenzone sodium) Benzophenone-6 (2,2'-dihydroxy ... Benzophenone-12 (octabenzone, used to protect plastics) Chemicalland21: Benzophenone Inhaltsstoffe Kosmetik: Benzophenone-11 ( ... 4'-dimethoxybenzophenone) Benzophenone-7 (5-chloro-2-hydroxybenzophenone) Benzophenone-8 (dioxybenzone) Benzophenone-9 (sodium ...
Benzophenone imine
Yet another route to benzophenone imine involves reaction of benzophenone and ammonia. Benzophenone imine undergoes ... Benzophenone imine is an organic compound with the formula of (C6H5)2C=NH. A pale yellow liquid, benzophenone imine is used as ... Benzophenone imine can be prepared by the thermal decomposition of benzophenone oxime: 2 (C6H5)2C=NOH → (C6H5)2C=NH + (C6H5)2C= ... Benzophenone imine can be used as an ammonia-equivalent in such reactions. Wolfe, John P.; Åhman, Jens; Sadighi, Joseph P.; ...
Benzophenone synthase
In enzymology, a benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes the chemical reaction 3 malonyl-CoA + 3- ... Beerhues L (April 1996). "Benzophenone synthase from cultured cells of Centaurium erythraea". FEBS Letters. 383 (3): 264-6. doi ...
Allergen of the Year
2014). Benzophenones named 2014 Contact Allergen of the Year Castanedo-Tardana, Mari Paz; Zug, Kathryn A. (2013). " ... Heurung, Ashley R.; Raju, Srihari I.; Warshaw, Erin M. (2014). "Benzophenones". Dermatitis. 25 (1): 3-10. doi:10.1097/DER. ... Benzophenones 2013 - Methylisothiazolinone - This chemical is used as a preservative in many cosmetics, lotions, and makeup ...
Diphenyldichloromethane
Alternatively, benzophenone is treated with phosphorus pentachloride: (C6H5)2CO + PCl5 → (C6H5)2CCl2 + POCl3 It undergoes ... Andrews, L. J.; W. W. Kaeding (1951). "The Formation of Benzophenone and its Diethylketal in the Ethanolysis of ... Marvel, C. S.; Sperry, W. M. (1941). "Benzophenone". Organic Syntheses.; Collective Volume, vol. 1, p. 95 Spaggiari, Alberto; ... hydrolysis to benzophenone. (C6H5)2CCl2 + H2O → (C6H5)2CO + 2 HCl It is used in the synthesis of tetraphenylethylene, ...
Steam distillation
C. S. Marvel, W. M. Sperry (1928). "Benzophenone". Organic Syntheses. 8: 26. doi:10.15227/orgsyn.008.0026. W. Klötzer, J. ... In one preparation of benzophenone, steam is employed to first recover unreacted carbon tetrachloride and subsequently to ... hydrolyze the intermediate benzophenone dichloride into benzophenone, which is in fact not steam distilled. It one preparation ...
Photoelectrochemical process
Cadmium; some of the noble gases, for example xenon; zinc; benzophenone; and a large number of organic dyes, are also used as ...
Geminal halide hydrolysis
Stephen aldehyde synthesis Marvel, C. S.; Sperry, W. M. (1928). "Benzophenone". Organic Syntheses. 8: 26. doi:10.15227/orgsyn. ...
Ketone
Acetone and benzophenone (C6H5C(O)C6H5) are symmetrical ketones. Acetophenone (C6H5C(O)CH3) is an unsymmetrical ketone. Many ... "Benzophenone". Organic Syntheses. 8: 26. doi:10.15227/orgsyn.008.0026. Furniss, Brian; Hannaford, Antony; Smith, Peter; ... for example acetone and benzophenone. These nonsystematic names are considered retained IUPAC names, although some introductory ...
Propolis
Clusia resin contains polyprenylated benzophenones. In some areas of Chile and Argentina Andean valleys, propolis contains ...
Garcinia pseudoguttifera
... benzophenone (vismiaphenone-C); and a new benzophenone, 2,2-dimethyl-8-benzoyl-3,7-dihydroxy-5-methoxy-6-(3-methyl-2-butenyl)-3 ... Four benzophenones have been isolated from Garcinia pseudoguttifera: 6-hydroxy-2,4-dimethoxy-3,5-bis(3-methyl-2-butenyl) ... Ali, Sadaquat; Goundar, Renee; Sotheeswaran, Subramaniam; Beaulieu, Christian; Spino, Claude (1 January 2000). "Benzophenones ... benzophenone (myrtiaphenone-A); 2,2-dimethyl-8-benzoyl-7-hydroxy-5-methoxy-6-(3-methyl-2-butenyl)benzopyran (myrtiaphenone-B); ...
Elbs reaction
The Elbs reaction is an organic reaction describing the pyrolysis of an ortho methyl substituted benzophenone to a condensed ... The first mechanism, suggested by Fieser, begins with a heat-induced cyclisation of the benzophenone, followed by a [1,3]- ...
Friedel-Crafts reaction
10: 32.{{cite journal}}: CS1 maint: uses authors parameter (link) C. S. Marvel, W. M. Sperry (1928). "Benzophenone" (PDF). ...
Photoprotection
see Benzophenone). Oxybenzone, titanium oxide and octyl methoxycinnamate are photoprotective agents used in many sunscreens, ...
Hydrazone
... s Benzophenone hydrazone, an illustrative hydrazone Carbonyl cyanide m-chlorophenyl hydrazone Gyromitrin (Acetaldehyde ... an antihypertensive drug X-ray structure of DNP-derived hydrazone of benzophenone. Selected parameters: C=N, 128 pm; N-N, 138 ... "Benzophenone 2,4-dinitrophenylhydrazone". Acta Crystallographica Section E. 62 (12): o5686-o5688. doi:10.1107/S1600536806048112 ...
2,4-Dinitrophenylhydrazine
"Benzophenone 2,4-dinitrophenylhydrazone". Acta Crystallographica Section E. 62 (12): o5686-o5688. doi:10.1107/S1600536806048112 ...
Radiation chemistry
"Flash Photolysis of Benzophenone" (PDF). Archived from the original (PDF) on 2011-07-20. Porter, George (11 December 1967). " ...
Oxybenzone
"Benzophenone-3 (BP-3) Factsheet". www.cdc.gov. 2017-12-01. Retrieved 2019-05-01. "Benzophenone-3 (BP-3) Factsheet , National ... Benzophenones can leach from food packaging, and are widely used as photo-initiators to activate a chemical that dries ink ... Oxybenzone or benzophenone-3 or BP-3 (trade names Milestab 9, Eusolex 4360, Escalol 567, KAHSCREEN BZ-3) is an organic compound ... Some brands market their sunscreens as "oxybenzone free" due to the negative perception of benzophenones In 2021 the U.S. FDA ...
Phenylsodium
Benzophenone is proposed as an intermediate. 2NaPh + PhCOCl → Ph3CONa + NaCl Metallation reactions with phenylsodium proceed in ...
Dioxybenzone
... (benzophenone-8) is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays. It ... is a derivative of benzophenone. It is a yellow powder with a melting point of 68 °C. It is insoluble in water, but moderately ... Benzophenones, All stub articles, Dermatologic drug stubs). ...
Nail polish
A typical stabilizer is benzophenone-1. This type of nail polish is a clear, milky-colored, or opaque pink polish formula that ...
Griseoxanthone C
... the methylated benzophenone intermediates". Biochemical Journal. 81 (1): 28-37. doi:10.1042/bj0810028. PMC 1243292. PMID ...
Diazirine
Benzophenones, which form reactive triplet carbonyl species upon irradiation, often require long periods of irradiation which ... Prestwich, Glenn D.; Dormán, György; Elliott, John T.; Marecak, Dale M.; Chaudhary, Anu (1997-02-01). "Benzophenone Photoprobes ...
Pinacol coupling reaction
Benzophenone may undergo the pinacol coupling photochemically. Benzaldehyde may also be used as a substrate with the use of ...
Xanthone
The Friedel-Crafts method has a benzophenone intermediate. The Robinson-Nishikawa method is a variant of the Hoesch synthesis ...
Sebastian Moiseevich Tanatar
24) Two modifications of benzophenone ( ib., 1892, vol. 24) Two modifications of chloroacetic acid (ib., 1892, vol. 24) On two ...
Thioketone
It photooxidizes in air to benzophenone and sulfur. Since its discovery, a variety of related thiones have been prepared. ...
Diphenylcyclopropenone
Benzophenone Cyclopropenone Singh G, Lavanya M (January 2010). "Topical immunotherapy in alopecia areata". International ...
Donald E. Pearson
D.E. Pearson; R.W. Brockman (1952). "The Effect of substituents on the Polargraphic Half-Wave Potentials of Benzophenones". ...
Benzophenone-3 (BP-3) Factsheet | National Biomonitoring Program | CDC
Sunscreens With Benzophenone-3 Unsuitable For Children
Sunscreens that contain benzophenone-3 provide effective protection against both UVA and UVB radiation, but these preparations ... The average total amount of benzophenone-3 excreted was 3.7%. We dont know how long it is stored, and we dont known whether ... Benzophenone-3 provides effective protection against both UVA and UVB radiation. The substance has been available since the ... It is known that benzophenone-3 can cause contact eczema, but there is limited knowledge about other adverse effects. Helena ...
Ingredients -- Benzophenone
benzophenone-1: 2,4-dihydroxy benzophenone benzophenone-2: 2,2,4,4-tetrahydroxy benzophenone benzophenone-5: 2-hydroxy-4- ... benzophenone-6: 2,2-dihydroxy-4,4-dimethoxy benzophenone benzophenone-9: 2,2-dihydroxy-4,4-dimethoxy benzophenone-5,5- ... while benzophenone-5 is used in water-based products. Benzophenone-6 is used in nail polish, and benzophenone-9 is used in bath ... benzophenone-bx-ahbp. 4-Allyloxy-2-hydroxy benzophenone This form is also added to plastic packaging as a UV blocker. It bonds ...
Chemical Database: Benzophenone (Diphenylketone) (EnvironmentalChemistry.com)
This page contains information on the chemical Benzophenone (Diphenylketone) including: 4 synonyms/identifiers. ... Benzophenone (Diphenylketone) Identifications. *Formula: C13H10O. Elements: Carbon, Hydrogen, Oxygen. *CAS Number: 119-61-9* ... Benzophenone (Diphenylketone) (EnvironmentalChemistry.com),/a,- This page contains information on the chemical Benzophenone ( ... Benzophenone (Diphenylketone) Related Resources. *USDOT Hazardous Materials Table 49 CFR 172.101. An online version of the ...
In utero exposure to benzophenone-2 causes hypospadias through an estrogen receptor dependent mechanism
Further study of human benzophenone-2 exposure and its effects is needed to support this hypothesis. ... These findings suggest that benzophenone-2 may cause hypospadias via signaling through the estrogen receptor. ... In pregnant women exposure may result in transplacental transfer of benzophenone-2 to fetuses. Benzophenone-2 is estrogenic in ... In utero exposure to benzophenone-2 causes hypospadias through an estrogen receptor dependent mechanism J Urol. 2007 Oct;178(4 ...
4,4'-Bis(dimethylamino)benzophenone, 98%, Thermo Scientific™
| Fisher Scientific
Shop 4,4-Bis(dimethylamino)benzophenone, 98%, Thermo Scientific™ at Fishersci.ca ... 4,4-bis dimethylamino benzophenone, bis 4-dimethylamino phenyl methanone, methanone, bis 4-dimethylamino phenyl, michler ... 4,4-bis dimethylamino benzophenone, bis 4-dimethylamino phenyl methanone, methanone, bis 4-dimethylamino phenyl, michler ... ketone, michlers ketone, michlers ketone, p,p-bis dimethylamino benzophenone, p,p-michlers ketone, ...
Enantioselective carbene insertion into the N-H bond of benzophenone imine - Chemical Science (RSC Publishing)
Efficient enantioselective insertion of α-diazoesters into the N-H bond of N-sp2-hybridized benzophenone imine was realized by ... Enantioselective carbene insertion into the N-H bond of benzophenone imine J. Yang, P. Ruan, W. Yang, X. Feng and X. Liu, Chem ... Efficient enantioselective insertion of α-diazoesters into the N-H bond of N-sp2-hybridized benzophenone imine was realized by ...
Human Metabolome Database: GC-MS Spectrum - Benzophenone EI-B (Non-derivatized) (HMDB0032049)
This project is supported by the Canadian Institutes of Health Research, Canada Foundation for Innovation, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Canada, Genome Alberta, and Genome British Columbia, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
Is benzophenone more polar than malonic acid? - Turningtooneanother.net
Benzophenone was partially soluble in hexane because hexane is nonpolar as is benzophenone. Thus, benzophenone was dissolved in ... Why is benzophenone insoluble in water?. Benzophenone is insoluble in water because water is a polar solvent. The polarity of ... Is benzophenone acidic or basic?. Since benzophenone can further delocalize this positive charge into its phenyl groups, the ... Is benzophenone more polar than malonic acid?. March 7, 2021. By admin Trendy ...
The mechanism of triplet energy transfer in solution : the quenching of excited-state benzophenone by transition-metal chelates...
Quenching of singlet benzophenone by the dibenzoylmethide chelates of iron and chromium is also observed. A possible ... Foss, Robert Paul (1963) The mechanism of triplet energy transfer in solution : the quenching of excited-state benzophenone by ... The mechanism of triplet energy transfer in solution : the quenching of excited-state benzophenone by transition-metal chelates ... The quenching of triplet-state benzophenone by transition-metal chelates of acetylacetone, dipivaloylmethane and ...
Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species
Species of the genus Garcinia have been the source of many benzophenone and xanthone derivatives. Recent data regarding potent ... Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species. Dzoyem JP, ... J.P. Dzoyem, et al., "Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) ... Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species. Phytochemistry ...
Benzophenone-3 | Wella Company
As part of sunscreen products, Benzophenone-3 (Oxybenzone) and Benzophenone-4 (Sulisobenzone) protect the skin or hair from the ... Benzophenone-3 absorbs and dissipates UV radiation, which serves to protect cosmetics and personal care products. ... Benzophenone-3. Benzophenone-3 absorbs and dissipates UV radiation, which serves to protect cosmetics and personal care ... As part of sunscreen products, Benzophenone-3 (Oxybenzone) and Benzophenone-4 (Sulisobenzone) protect the skin or hair from the ...
3H]Benzophenone Photolabeling Identifies State-Dependent Changes in Nicotinic Acetylcholine Receptor Structure
Interactions of benzophenone (BP) with the Torpedo nicotinic acetylcholine receptor (nAChR) were characterized by ... 3H]Benzophenone Photolabeling Identifies State-Dependent Changes in Nicotinic Acetylcholine Receptor Structure. ... View more ,Interactions of benzophenone (BP) with the Torpedo nicotinic acetylcholine receptor (nAChR) were characterized by ...
NHANES 2007-2008: Environmental Phenols Data Documentation, Codebook, and Frequencies
URXBP3 - Urinary Benzophenone-3 (ng/mL). Variable Name: URXBP3. SAS Label: Urinary Benzophenone-3 (ng/mL). English Text: ... URDBP3LC - Urinary Benzophenone-3 comment Variable Name: URDBP3LC. SAS Label: Urinary Benzophenone-3 comment English Text: ... Urinary 2-Hydroxy-4-metoxybenzophenone (Benzophenone-3). Target: Both males and females 6 YEARS - 150 YEARS. Code or Value. ... Urinary 2-Hydroxy-4-metoxybenzophenone (Benzophenone-3) comment code. Target: Both males and females 6 YEARS - 150 YEARS. Code ...
CosIng - Cosmetics - GROWTH - European Commission
BENZOPHENONE-4
... nu penetreaza pielea in profunzime dar intensifica abilitatea altor chimicale s-o facaprotejeaza cosmeticele si ... BENZOPHENONE-4. Copierea de continut din prezentul site este supusa regulilor precizate in Termeni si conditii! Click aici. ... Cosmetic Ingredient Review (CIR) permite folosirea Benzophenone-4 in cosmetice si produse de ingrijire personala.. Conform ...
Benzophenone | C13H10O | ChemSpider
305 °C Food and Agriculture Organization of the United Nations Benzophenone. 305 °C OU Chemical Safety Data (No longer updated) ... The simplest member of the class of benzophenones, being formaldehyde in which both hydrogens are replaced by phenyl groups. ... crystals or flakes with a mild powdery floral odour Food and Agriculture Organization of the United Nations Benzophenone. ...
Benzophenone - Xcess Biosciences
Benzophenone 4 Exporter,Supplier,Trader
... trader of Benzophenone 4 based in Vadodara, Gujarat, India ... Find online Benzophenone 4, We NUEVA CHEMIE LLP are one of the ... Benzophenone-4 is photostabilizer and sunscreen agent used for its ability to absorb UV rays. It helps prevent the integrity of ... We are offering here the Benzophenone-4 that is within a group of aromatic ketones that contain both UVB and UVA absorbing ...
BENZOPHENONE-3 - Sun Care - AAKO
Benzophenone-3 is being used in a wide range of cosmetic products to provide an appropriate Sun Protection Factor (SPF) in ... AakoSun BP3 is better known as Benzophenone-3. It is an organic, oil-soluble sun filter that absorbs both UV-A and UV-B ... Benzophenone-3 is also known under the names Oxybenzone, 2-Hydroxy-4-Methoxybenzophenone. ...
Concentrations of the Sunscreen Agent Benzophenone-3 in Residents of the United States: National Health and Nutrition...
Benzophenones Child Chromatography, High Pressure Liquid Female Health Surveys Humans Male Mass Spectrometry Racial Groups Sex ... The capability of benzophenone-3 (BP-3) to absorb and dissipate ultraviolet radiation facilitates its use as a sunscreen agent ... Title : Concentrations of the Sunscreen Agent Benzophenone-3 in Residents of the United States: National Health and Nutrition ... Concentrations of the Sunscreen Agent Benzophenone-3 in Residents of the United States: National Health and Nutrition ...
Benzophenones-12, Chloro Paraffins Importers in Canada, India | Eximcan
Drug-Induced Photosensitivity Differential Diagnoses
Drug-induced photosensitivity refers to the development of cutaneous disease as a result of the combined effects of a chemical and light. Exposure to either the chemical or the light alone is not sufficient to induce the disease; however, when photoactivation of the chemical occurs, one or more cutaneous manifestations may arise.
Propiophenone and others|Benzophenone Derivatives--Sino-High (China) Co., Ltd.
Benzophenone-3 | Watch-out database - COSlaw.eu - Guiding through EU Cosmetics Regulations
Benzophenone 3 (Oxybenzone) | Products | First Continental International | Window to the Chemical World
3,5-Bis(trifluoromethyl)benzophenone,21221-93-2,C15H8F6O - Speranza Chemical Co., Ltd.
Benzophenone-1 and -2 UV-filters potently inhibit human, rat, and mouse gonadal 3ß-hydroxysteroid dehydrogenases: Structure...
Benzophenone (BP) ultraviolet (UV) -filters have been widely used to prevent adverse effects of UV. Whether they can disrupt ... Benzophenone-1 and -2 UV-filters potently inhibit human, rat, and mouse gonadal 3ß-hydroxysteroid dehydrogenases: Structure- ... Benzophenone-1 and -2 UV-filters potently inhibit human, rat, and mouse gonadal 3ß-hydroxy ...
Urinary concentrations of benzophenone type ultraviolet light filters and semen quality | Fertility and Sterility Dialog
Urinary concentrations of two benzophenone-type ultraviolet filters (BP-2, BP-8), chemicals used as sunscreens, were found to ... Urinary concentrations of benzophenone type ultraviolet light filters and semen quality. Urinary concentrations of two ... To assess benzophenone-type ultraviolet (UV) filter concentrations, chemicals used in sunscreen and personal care products, and ... Urinary concentrations of benzophenone type ultraviolet light filters and semen quality. Urinary concentrations of two ...
TriclosanSunscreenOxybenzoneStyreneCompoundsDerivativesIngredientBisphenolsSunscreensSodiumSingletDiphenylketoneUltraviolet lightAbsorbsProductsAcidsRadiationAlcoholChemicalsAllergyWaterFiltersParabensIngredientsPropylene glycolPresence of benzophenoneTriclosanConcentrationsOctocryleneCocodimonium Hydroxypropyl Hydrolyzed KeratinActivity of benzophenonesFragrancePropylparabenPhthalatesAbsorb and dissipateBenzalkonium chlorideOctylVitroSulisobenzoneMethacrylateBenzoicExposureEthanolCarbonylXanthonesAcetophenoneUltraviolet filtersChemicalSunscreen ingredientSynonymGarcinia
Triclosan7
- Phenols are also used as sunscreen agents for skin protection, and as UV filters in cosmetic products and plastics to improve stability (e.g., benzophenone-3 [BP-3]), or used as bactericides (e.g., triclosan) in soap and other personal care products. (cdc.gov)
- We have developed a sensitive method for measuring BPA, 4-tert-octylphenol (tOP), benzophenone-3 (BP-3), one chlorophenols triclosan, and four parabens. (cdc.gov)
- Parabens (p-hydroxybenzoic acid esters), bisphenols, benzophenone-type UV filters, triclosan, and triclocarban are used in a variety of consumer products, including baby teethers. (mendeley.com)
- Triclosan and triclocarban were found in the extracts of teethers at approximately 10-fold less amounts than were bisphenols and benzophenones. (mendeley.com)
- Results: Correlations between exposure estimates from pools of all and of only three voids per day were above 0.80 for all time windows and compounds, except for benzophenone-3 and triclosan in the daily time window (correlations, 0.57-0.68). (inserm.fr)
- STUDY QUESTION: Are urinary phenol concentrations of methylparaben, propylparaben, butylparaben, triclosan, benzophenone-3, 2,4-dichlorophenol or 2,5-dichlorophenol associated with fecundability and early pregnancy loss SUMMARY ANSWER: 2,5-dichlorophenol concentrations were associated with an increased odds of early pregnancy loss, and higher concentrations of butylparaben and triclosan were associated with an increase in fecundability. (cdc.gov)
- Free of added potentially harmful hormone-altering chemicals and ingredients that may affect teen development such as Phthalates, Bisphenols, Parabens, halogenated phenols (such as Triclosan), Benzophenone-3, Perfluoro (PFAS) compounds, hexylresorcinol, and related ingredients. (skinsafeproducts.com)
Sunscreen5
- Helena Gonzalez carried out a study in which 26 people applied sunscreen containing 4% benzophenone-3 to the complete skin morning and evening for five days. (medicalnewstoday.com)
- The urine still contained benzophenone-3 five days after stopping using the sunscreen, a result that suggests that the substance is being stored in the body. (medicalnewstoday.com)
- As part of sunscreen products, Benzophenone-3 (Oxybenzone) and Benzophenone-4 (Sulisobenzone) protect the skin or hair from the harmful effects of the sun. (wellacompany.com)
- Benzophenone-4 is photostabilizer and sunscreen agent used for its ability to absorb UV rays. (nuevachemie.com)
- To assess benzophenone-type ultraviolet (UV) filter concentrations, chemicals used in sunscreen and personal care products, and semen endpoints. (fertstertdialog.com)
Oxybenzone1
- BENZOPHENONE/OXYBENZONE This can be found in sunscreens and could promote the growth of potentially harmful free radicals. (shirliesdaughters.com)
Styrene1
- Hanami has also got rid of Benzophenone-1 and Styrene from their formula - way less chemicals and so much better for you than commercial nail polish! (naturallyfabulous.nz)
Compounds2
- We found metals, acrylates, and benzophenone in filter particulate and volatile compounds and benzophenone in brewery air. (cdc.gov)
- Phytochemicals studies of P. macrocarpa revealed the presence of several classes of compounds such as benzophenones, terpenoids, xanthones, lignans, acids, and sugars. (ljmu.ac.uk)
Derivatives5
- Species of the genus Garcinia have been the source of many benzophenone and xanthone derivatives. (uni-bielefeld.de)
- Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species", Phytochemistry Letters , vol. 14, 2015, pp. 153-158. (uni-bielefeld.de)
- Benzophenone Derivatives--Sino-High (China) Co., Ltd. (thewifineighbor.com)
- Benzophenone and its derivatives are commonly used UVB absorbers. (science.org.au)
- Derivatives of benzophenone (with the structural formula phenyl-(C=O)-phenyl). (bvsalud.org)
Ingredient1
- Cosmetic Ingredient Review (CIR) permite folosirea Benzophenone-4 in cosmetice si produse de ingrijire personala. (alegesanatos.ro)
Bisphenols2
- Elevated concentrations of bisphenols, benzophenones, and antimicrobials in pantyhose collected from six countries. (greenmedinfo.com)
- The total amount of the sum of nine bisphenols (Σ9 bisphenols) and 5 benzophenones (Σ5 benzophenones) leached from teethers ranged from 1.93 to 213 ng and 0.59 to 297 ng, respectively. (mendeley.com)
Sunscreens7
- Sunscreens that contain benzophenone-3 provide effective protection against both UVA and UVB radiation, but these preparations should not be used for young children. (medicalnewstoday.com)
- There has been a certain amount of discussion about Benzophenone-3, and it is for this reason not common in Swedish sunscreens. (medicalnewstoday.com)
- We don't know how long it is stored, and we don't known whether it is important, but I suggest that parents of small children should avoid using sunscreens that contain benzophenone-3, to be on the safe side', says Helena Gonzalez. (medicalnewstoday.com)
- Benzophenone (Diphenyl ketone, Benzoylbenzene) filters out both UVA and UVB rays and is widely used in a great variety of sunscreens and personal care products. (xcessbio.com)
- Benzophenone-3 is being used in a wide range of cosmetic products to provide an appropriate Sun Protection Factor (SPF) in sunscreens or to protect cosmetics against UV radiation. (aako.nl)
- Urinary concentrations of two benzophenone-type ultraviolet filters (BP-2, BP-8), chemicals used as sunscreens, were found to be associated with select semen endpoints. (fertstertdialog.com)
- They're also good UVB absorbers, hence their use in sunscreens (often in combination with benzophenones). (science.org.au)
Sodium1
- 2. Reagent-grade tetrahydrofuran (Fisher Scientific Company) was either freshly distilled from sodium metal and benzophenone or dried for at least 24 hr over activated Linde 4-Å molecular sieves. (orgsyn.org)
Singlet1
- Quenching of singlet benzophenone by the dibenzoylmethide chelates of iron and chromium is also observed. (caltech.edu)
Diphenylketone1
- Chemical Database - Benzophenone (Diphenylketone). (environmentalchemistry.com)
Ultraviolet light2
- Benzophenone is used to prevent ultraviolet light from damaging scents and colors in products such as perfumes and soaps. (sci-toys.com)
- Additives such as benzophenone-2 are commonly used in cosmetic products and food container plastics to filter out ultraviolet light. (nih.gov)
Absorbs1
- Benzophenone-3 absorbs and dissipates UV radiation, which serves to protect cosmetics and personal care products. (wellacompany.com)
Products4
- For example, benzophenone-2 is used in alcohol-based products, while benzophenone-5 is used in water-based products. (sci-toys.com)
- Benzophenone-6 is used in nail polish, and benzophenone-9 is used in bath products and skin care products. (sci-toys.com)
- Benzophenone-3 will be permitted as an UV-filter: (1) up to 6% in face products, hand products, and lip products, excluding propellant and pump spray products. (coslaw.eu)
- Products made with the chemical may contain benzophenone, a suspected carcinogen that also can interfere with key hormones and reproductive organs, according to a group led by Craig Downs, executive director of the nonprofit Haereticus Environmental Laboratory', which studies risks to health and the environment. (obrag.org)
Acids2
- Since benzophenone can further delocalize this positive charge into its phenyl groups, the conjugate acid of benzophenone is the most stabilized of the three acids, leading to benzophenone being the strongest base. (turningtooneanother.net)
- Interactions of benzophenone (BP) with the Torpedo nicotinic acetylcholine receptor (nAChR) were characterized by electrophysiological analyses, radioligand binding assays, and photolabeling of nAChR-rich membranes with [3H]BP to identify the amino acids contributing to its binding sites. (edu.au)
Radiation1
- Benzophenone-3 provides effective protection against both UVA and UVB radiation. (medicalnewstoday.com)
Alcohol1
- Benzophenone, which is largely nonpolar, but possesses a polar carbonyl group, was found to be partially soluble in methyl alcohol and hexane but insoluble in water. (turningtooneanother.net)
Chemicals1
- This product can expose you to chemicals including quartz and benzophenone, which are known to the State of California to cause cancer. (northlineexpress.com)
Allergy1
- Free of formaldehyde and the most common allergy causing preservatives such as benzalkonium chloride, formaldehyde, benzophenone, methyldibromo glutaronitrile, MCI/MI and others. (skinsafeproducts.com)
Water2
- Why is benzophenone insoluble in water? (turningtooneanother.net)
- Benzophenone is insoluble in water because water is a polar solvent. (turningtooneanother.net)
Filters2
- Benzophenone-1 and -2 UV-filters potently inhibit human, rat, and mouse gonadal 3ß-hydroxysteroid dehydrogenases: Structure-activity relationship and in silico docking analysis. (bvsalud.org)
- Benzophenone (BP) ultraviolet (UV) - filters have been widely used to prevent adverse effects of UV. (bvsalud.org)
Parabens4
- We have developed a sensitive method for measuring BPA, 4-tert-octylphenol (tOP), benzophenone-3 (BP-3), one chlorophenols triclosan, and four parabens. (cdc.gov)
- Work published in Environmental Research suggests that frequency of cosmetics use is a strong predictor of exposure to benzophenone and parabens, and that these compounds may increase the risk of endometriosis. (cosmeticsandtoiletries.com)
- Free of added potentially harmful hormone-altering chemicals and ingredients that may affect teen development such as Phthalates, Bisphenols, Parabens, halogenated phenols (such as Triclosan), Benzophenone-3, Perfluoro (PFAS) compounds, hexylresorcinol, and related ingredients. (skinsafeproducts.com)
- All of their masks are made without Parabens, Harsh dyes, Pigment, Mineral Oil, Artificial Fragrance and Benzophenone. (thepinklife.ca)
Ingredients8
- Instead of penetrating the skin to a large degree, Benzophenone-4 enhances the ability of other ingredients to penetrate. (aako.nl)
- These Benzophenone ingredients are also used in bath products, makeup products, hair products, sunscreens and skin care products. (cosmeticsuppliesusa.com)
- The Food and Drug Administration (FDA) has approved the use of Benzophenone-3 and Benzophenone-4 as safe and effective, over-the-counter (OTC) sunscreen ingredients. (cosmeticsuppliesusa.com)
- Benzophenone ingredients absorb and dissipate UV radiation, which serves to protect cosmetics and personal care products. (cosmeticsuppliesusa.com)
- ACTIVE INGREDIENTS: Octyl Methoxycinnamate, Benzophenone-3. (organickingdom.com)
- History of severe allergic reactions (Anaphylaxis) to several allergins and specific allergies to or other substances found in the stent or impression material (ie: Plasticized Methacrylate Polymer, methyl methacrylate monomer, alkyl dimethacrylate, benzophenone, Toluidine and Hydroquinone), waxes containing Pine Rosin, and to the list of ingredients for the impression material. (nih.gov)
- SPF 30 Gel contains the active ingredients octylmethoxycinnamate, octyl salicylate, benzophenone-3, and avobenzone. (skinblends.com)
- Four commonly found sunscreen ingredients: paraben, cinnamate, benzophenone, and a camphor derivative can awaken dormant viruses that live inside reef-building coral species. (malibu90265magazine.com)
Propylene glycol2
- At 8-h, the highest concentration of benzophenone-3 in skin was obtained with propylene glycol, and O/W submicron emulsion. (sigmaaldrich.com)
- FDA approved SD Alcohol + Water + Fragrance Oil + Glycerin + Propylene Glycol + Benzophenone-2. (urbanwanderlustcandles.com)
Presence of benzophenone3
- Cationic ROMP-polymers bearing ammonium or phosphonium groups were photo-grafted onto a PDMS surface via the thiol-ene click reaction, in the presence of benzophenone. (yildiz.edu.tr)
- The PDMS surface was first thiolated using pentaerythritol tetrakis (3-mercaptopropionate) (PTTMP) under UV, in the presence of benzophenone. (yildiz.edu.tr)
- The TGA is currently investigating this issue and is conducting testing of samples of sunscreen products containing benzene as well as products containing octocrylene for the presence of benzophenone and compliance with existing standards," a spokesman told News.com.au. (skynews.com.au)
Triclosan1
- Phenols are also used as sunscreen agents for skin protection, and as UV filters in cosmetic products and plastics to improve stability (e.g., benzophenone-3 [BP-3]), or used as bactericides (e.g., triclosan) in soap and other personal care products. (cdc.gov)
Concentrations2
- The new research identifies that benzophenone-3 and propylparaben, even in very low concentrations, can damage DNA in breast cells, and add to breast cancer risk. (organicfacts.net)
- After single 4-hour inhalation primers of benzophenone at concentrations of 35.2, 94.6 and 200 mg/m3, there were no violations of the synthetic and enzymatic functions of the liver. (medlit.ru)
Octocrylene3
- In another US study, Haereticus Environmental Laboratory found sunscreen products that contained the permitted ingredient of octocrylene were found to include another known carcinogen - benzophenone. (skynews.com.au)
- Octocrylene naturally degrades into the chemical, benzophenone, in over a dozen popular products," the lab wrote. (skynews.com.au)
- What researchers have discovered is that three UV filters (octylmethoxycinnamate, benzophenone-3 and octocrylene) that are used in a wide variety of sunscreens can actually generate ROS once they get absorbed into the deeper layers of your skin and are exposed to ultraviolet radiation. (drbenkim.com)
Cocodimonium Hydroxypropyl Hydrolyzed Keratin1
- Benzophenone-4 · Polyquaternium-10 · Cocodimonium Hydroxypropyl Hydrolyzed Keratin · Maris Sal (Sea Salt) · Hydrolyzed Pearl · Hydrolyzed Keratin. (schwarzkopf.com)
Activity of benzophenones2
- 3. In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. (nih.gov)
- Leishmanicidal activity of benzophenones and extracts from Garcinia brasiliensis Mart. (thefreedictionary.com)
Fragrance1
- Benzophenone-2 (BP2) is widely used as a UV screen in both industrial products and cosmetic formulations, where it is frequently found associated with fragrance compounds, such as isoeugenol and coumarin. (sigmaaldrich.com)
Propylparaben1
- The researchers compared the ultraviolet filter benzophenone-3 (BP-3), found in sunscreen, and propylparaben (PP), a preservative found in cosmetics and other personal care products, with a form of estrogen called 17 beta estradiol (E2). (nih.gov)
Phthalates1
- The LIFE study found that the EDC methyl paraben affects fertility in women, while phthalates and the UV filter benzophenone-2 affect fertility in men. (nih.gov)
Absorb and dissipate1
- The capability of benzophenone-3 (BP-3) to absorb and dissipate ultraviolet radiation facilitates its use as a sunscreen agent. (medscape.com)
Benzalkonium chloride1
- Free of formaldehyde and the most common allergy causing preservatives such as benzalkonium chloride, formaldehyde, benzophenone, methyldibromo glutaronitrile, MCI/MI and others. (skinsafeproducts.com)
Octyl1
- In vitro effects of benzophenone-2 and octyl-methoxycinnamate on the production of interferon-gamma and interleukin-10 by murine splenocytes. (sigmaaldrich.com)
Vitro3
- LC analysis of benzophenone-3: II application to determination of 'in vitro' and 'in vivo' skin penetration from solvents, coarse and submicron emulsions. (sigmaaldrich.com)
- The aim of this study was to determine the skin penetration of benzophenone-3 in vitro and in vivo in order to investigate a possible influence of formulation. (sigmaaldrich.com)
- The in vitro and in vivo skin penetration capacity of benzophenone-3 from six vehicles was confirmed and quantified. (sigmaaldrich.com)
Sulisobenzone1
- Benzophenone-4 is also known under the names Sulisobenzone and 1-phenol-4-sulfonic acid . (aako.nl)
Methacrylate1
- Dynamic Response of Anchored Poly(N-isopropylacrylamide-co-methacrylic acid-co benzophenone methacrylate) Terpolymer Hydrogel Layers to Physicochemical Stimuli. (mpg.de)
Benzoic2
- Click hereð to get an answer to your question ï¸ Benzaldehyde to benzophenone Benzoic acid to m-Nitrobenzyl alcohol 12:39 87.1k LIKES. (newcastlenyc.com)
- In either case, with benzoic acid in hand, you can procede as you've indicated, on to benzophenone. (newcastlenyc.com)
Exposure2
- Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile. (sigmaaldrich.com)
- Approximate safe level of exposure to benzophenone in the air in the working area is 2 mg/m3 (aerosol). (medlit.ru)
Ethanol1
- A solution of 25 g. (0.14 mole) of benzophenone in 125 ml. of 95% ethanol is placed in the flask, which is cooled in an ice-salt freezing mixture. (orgsyn.org)
Carbonyl3
- to Three Dimensional Geometry, Application The key difference between acetophenone and benzophenone is that acetophenone has a methyl group and a benzene ring attached to the carbonyl carbon, whereas benzophenone has a benzene ring attached to the carbonyl carbon. (newcastlenyc.com)
- I think that the carbonyl group which is a functional group composed of a carbon atom double-bonded to an oxygen atom $(\ce{C=O})$ of benzophenone will react to the alkyl halide. (stackexchange.com)
- The first step details the preparation of a phosphonium ylide, which subsequently is allowed to react with the carbonyl compound (benzophenone in our case) to yield the final product, 1,1-diphenyl-1-butene. (stackexchange.com)
Xanthones3
- 5. Xanthones and benzophenones from Garcinia griffithii and Garcinia mangostana. (nih.gov)
- 8. Prenylated xanthones and benzophenones from the fruits of Garcinia bracteata and their potential antiproliferative and anti-inflammatory activities. (nih.gov)
- 17. Anti-HIV and cytotoxic biphenyls, benzophenones and xanthones from stems, leaves and twigs of Garcinia speciosa. (nih.gov)
Acetophenone2
- The reagent which can be used to distinguish acetopheone from benzophenone is : The reagent (s) which can be used to distinguish acetophenone from benzophenone is (are), Rajasthan Govt. (newcastlenyc.com)
- 2. To demonstrate a different structural effect on \(R_f\), an eluted TLC plate of acetophenone and benzophenone is shown in Figure 2.20. (newcastlenyc.com)
Ultraviolet filters1
- Sensitive detection of benzophenone-type ultraviolet filters in plastic food packaging materials by sheathless capillary electrophoresis-electrospray ionization-tandem mass spectrometry. (sigmaaldrich.com)
Chemical5
- Benzophenone-3 (BP-3) is a naturally occurring chemical found in some flowering plants. (cdc.gov)
- 4,4'-Difluoro-Benzophenone--Yingkou Xingfu Chemical Co., Ltd. (modemlaris.com)
- These benzophenone-alkyne s receptor ligands might therefore be amenable for studying the s2-18k protein through chemical biology approaches. (iuc.edu.tr)
- Processors have had limited success in reducing the migration of benzophenone from packaging to foods, with 17 per cent of samples testing positive for the printing chemical, according to a UK study. (foodnavigator.com)
- 2004) benzophenone-3 (R2) oxtinoxate (R2) octadimethyl PABA (R2) a General use categories obtained from the NLM Hazardous Substance Data Bank and/or scientific literature b Health effects have not necessarily been reported for all chemicals within the chemical class. (cdc.gov)
Sunscreen ingredient1
- Benzophenone-1 is another sunscreen ingredient with estrogenic properties binding to and stimulating human estrogen receptors and increasing uterine weight in animal studies. (bellaonline.com)
Synonym1
- 4-(Dimethylamino) benzophenone 98% Synonym: 4-Benzoyl-N,N-dimethylaniline, p-Benzoyl-N,N-dimethylaniline CAS Number 530-44-9. (newcastlenyc.com)
Garcinia6
- 9. Bioactive benzophenones from Garcinia xanthochymus fruits. (nih.gov)
- 11. Benzophenones and biflavonoids from Garcinia livingstonei fruits. (nih.gov)
- 13. Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric. (nih.gov)
- 14. Identification and quantification of two biologically active polyisoprenylated benzophenones xanthochymol and isoxanthochymol in Garcinia species using liquid chromatography-tandem mass spectrometry. (nih.gov)
- 15. Isoprenylated xanthone and benzophenone constituents of the pericarp of Garcinia planchonii. (nih.gov)
- 18. The potential health benefit of polyisoprenylated benzophenones from Garcinia and related genera: ethnobotanical and therapeutic importance. (nih.gov)