Benzoates
Oxygenases
Benzoic Acid
Sodium Benzoate
Mixed Function Oxygenases
Kynurenine 3-Monooxygenase
Methylococcaceae
Methylococcus capsulatus
Biodegradation, Environmental
Benzoate 4-Monooxygenase
Pseudomonas
Cytochrome P-450 Enzyme System
Parabens
Methylosinus trichosporium
Flavin-Adenine Dinucleotide
Oxidation-Reduction
Camphor 5-Monooxygenase
Methane
Pseudomonas putida
Nitrosomonas
Hydroxybenzoates
Molecular Sequence Data
Alkane 1-Monooxygenase
Hydroxylation
Benzydamine
Azoarcus
Oxidoreductases
Tyrosine 3-Monooxygenase
Hydrocarbons, Aromatic
Squalene Monooxygenase
Substrate Specificity
FMN Reductase
NADPH-Ferrihemoprotein Reductase
Anaerobiosis
Amidine-Lyases
Estradiol
Multienzyme Complexes
Flavins
Dioxygenases
Crotonates
Trichloroethylene
Xylenes
Deltaproteobacteria
Microsomes, Liver
Catalysis
Methylocystaceae
Catechol 1,2-Dioxygenase
Amino Acid Sequence
Gram-Negative Aerobic Bacteria
Beijerinckiaceae
Rhodopseudomonas
Cloning, Molecular
Ammonia
Thauera
Alkanes
NADP
Oxidoreductases, O-Demethylating
Ivermectin
7-Alkoxycoumarin O-Dealkylase
Pseudomonas mendocina
Alkenes
Oxygen
Multigene Family
Salicylanilides
Acinetobacter
Biotransformation
Dichloroethylenes
Burkholderia
Gene Expression Regulation, Bacterial
Spectrophotometry
Enzyme Induction
Base Sequence
Pseudomonas stutzeri
Escherichia coli
Sequence Analysis, DNA
Acetone
Copper
Chloroquinolinols
Sequence Homology, Amino Acid
Tryptophan Hydroxylase
Epoxy Compounds
Glyceryl Ethers
Flavin Mononucleotide
4-Hydroxybenzoate-3-Monooxygenase
Camphor
Iron
Hydrogen-Ion Concentration
Alcaligenes
Acetates
Alkanesulfonates
Microsomes
Food Preservatives
Molecular Structure
Progesterone
Ralstonia
Chromatography, High Pressure Liquid
Models, Chemical
Styrene
Indigo Carmine
Testolactone
Methimazole
Acinetobacter calcoaceticus
Soil Microbiology
NAD
Binding Sites
Hydrocarbons, Chlorinated
ortho-Aminobenzoates
Phenobarbital
Stereoisomerism
Betaproteobacteria
Operon
Styrenes
Cinnamomum zeylanicum
Sulfides
Phenylalanine Hydroxylase
Plasmids
Phenylacetates
Aryl Hydrocarbon Hydroxylases
Crystallography, X-Ray
Methanococcaceae
Models, Molecular
Streptomyces
Culture Media
Methylococcus
Benzene
Anthraquinones
Euryarchaeota
Rhodotorula
Liver
Cytochromes b5
Benzyl Alcohols
Biocatalysis
Luteinizing Hormone
Sequence Alignment
Acyl Coenzyme A
Gas Chromatography-Mass Spectrometry
NADH, NADPH Oxidoreductases
Salicylates
Steroid Hydroxylases
Raccoons
Spectrophotometry, Ultraviolet
Carboxylic Acids
Mutation
Gram-Negative Aerobic Rods and Cocci
beta-Carotene 15,15'-Monooxygenase
Insecticides
Estrus
Solubility
Catalytic Domain
Benzopyrene Hydroxylase
Nitrosomonas europaea
Phthalic Acids
Ferredoxins
RNA, Ribosomal, 16S
Estrus Synchronization
Methanospirillum
Methylomonas
Hydrolases
Cytochrome P450rm from Rhodotorula minuta catalyzes 4-hydroxylation of benzoate. (1/1)
Rhodotorula minuta, a red yeast, produces a cytochrome P450, tentatively named P450rm, catalyzing the formation of isobutene from isovalerate. We found that P450rm interacted with benzoate and the dissociation constant of P450rm for benzoate was 36 microM. A reconstituted system that consisted of purified P450rm and cytochrome P450 reductase catalyzed the 4-hydroxylation of benzoate in addition to the formation of isobutene; the turnover rate was approximately 40 nmol/min/nmol P450rm. The P450rm-monooxygenase system was specific for benzoate and did not catalyze hydroxylation of other aromatic carboxylates. Since only a benzoate 4-hydroxylase that requires tetrahydropteridine has been isolated to date, P450rm appears to be the first isolated cytochrome P450 that acts as a benzoate 4-hydroxylase. The P450rm-monooxygenase system in microsomes of R. minuta might function in the degradation of L-phenylalanine on the pathway to beta-ketoadipate. (+info)Ectoparasitic Infestations can be caused by various factors such as poor hygiene, close contact with infected individuals, or exposure to areas where the parasites are present. They can be diagnosed through physical examination and medical tests, such as blood tests or skin scrapings.
Treatment for Ectoparasitic Infestations depends on the type of parasite and the severity of the infestation. Common treatments include insecticides, medicated shampoos, and topical creams or lotions. In some cases, oral medications may be prescribed to treat more severe infestations.
Prevention is key in avoiding Ectoparasitic Infestations. This includes practicing good hygiene, using protective clothing and gear when outdoors, and avoiding close contact with individuals who have known infestations. Regularly inspecting and cleaning living spaces can also help prevent the spread of these parasites.
In conclusion, Ectoparasitic Infestations are a common health issue that can cause a range of health problems. Diagnosis and treatment depend on the type of parasite and the severity of the infestation, while prevention involves practicing good hygiene and taking precautions to avoid close contact with individuals who have known infestations.
Symptoms of CPS1 deficiency disease can vary in severity and may include seizures, developmental delays, poor muscle tone, confusion, and psychomotor retardation. The disorder is usually diagnosed in infancy or early childhood, and patients may experience a range of cognitive and physical disabilities. Treatment for CPS1 deficiency disease typically involves a low-protein diet, supplements to reduce ammonia production, and medications to manage symptoms such as seizures and neurological problems. In severe cases, liver transplantation may be necessary.
CPS1 deficiency disease is an autosomal recessive disorder, meaning that patients must inherit two copies of the mutated gene - one from each parent - to develop the condition. Carrier testing and prenatal testing are available for individuals who have a family history of the disorder or are at risk of being carriers. Early detection and treatment can help manage symptoms and prevent complications, but there is currently no cure for CPS1 deficiency disease.
Methods1
- Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl peptidase-4) inhibitors. (bvsalud.org)