A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.
Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.
Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Analogs or derivatives of prostaglandins F that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGF.
The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.
A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.
Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Chemical substances that are destructive to spermatozoa used as topically administered vaginal contraceptives.
A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.
The presence of organisms, or any foreign material that makes a drug preparation impure.
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
Compounds in which a methyl group is attached to the cyano moiety.
The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid.
Human or animal tissue used as temporary wound coverings.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.
An annular transitional zone, approximately 1 mm wide, between the cornea and the bulbar conjunctiva and sclera. It is highly vascular and is involved in the metabolism of the cornea. It is ophthalmologically significant in that it appears on the outer surface of the eyeball as a slight furrow, marking the line between the clear cornea and the sclera. (Dictionary of Visual Science, 3d ed)
Diseases of the cornea.
Sterile solutions used to clean and disinfect contact lenses.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.
Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.
Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. These are distinguished from IMINES which are RN=CR2.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
A species of the genus PARVOVIRUS and a host range variant of FELINE PANLEUKOPENIA VIRUS. It causes a highly infectious fulminating ENTERITIS in dogs producing high mortality. It is distinct from CANINE MINUTE VIRUS, a species in the genus BOCAVIRUS. This virus can also infect cats and mink.
Any preparations used for cleansing teeth; they usually contain an abrasive, detergent, binder and flavoring agent and may exist in the form of liquid, paste or powder; may also contain medicaments and caries preventives.
The pathologic wearing away of the tooth substance by brushing, bruxism, clenching, and other mechanical causes. It is differentiated from TOOTH ATTRITION in that this type of wearing away is the result of tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces. It differs also from TOOTH EROSION, the progressive loss of the hard substance of a tooth by chemical processes not involving bacterial action. (From Jablonski, Dictionary of Dentistry, 1992, p2)
The fixed oil obtained from the dried ripe seed of linseed, Linum usitatissimum (L. Linaceae). It is used as an emollient in liniments, pastes, and medicinal soaps, and in veterinary medicine as a laxative. It is also called flaxseed oil. (Dorland, 28th ed)
A non-crystalline form of silicon oxide that has absorptive properties. It is commonly used as a desiccating agent and as a stationary phase for CHROMATOGRAPHY. The fully hydrated form of silica gel has distinct properties and is referred to as SILICIC ACID.
The act of cleaning teeth with a brush to remove plaque and prevent tooth decay. (From Webster, 3d ed)
Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.
An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)
A characteristic symptom complex.
Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.
Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.
The effect of environmental or physiological factors on the driver and driving ability. Included are driving fatigue, and the effect of drugs, disease, and physical disabilities on driving.
Two-wheeled, engine-driven vehicles.
A usually four-wheeled automotive vehicle designed for passenger transportation and commonly propelled by an internal-combustion engine using a volatile fuel. (Webster, 1973)

Effects of benzalkonium chloride on growth and survival of Chang conjunctival cells. (1/234)

PURPOSE: The aim of this study was to investigate the action of benzalkonium chloride (BAC), used as a preservative in most ophthalmic topical solutions, on epithelial conjunctival cells in vitro. METHODS: A continuous human conjunctival cell line (Wong-Kilbourne derivative of Chang conjunctiva) was exposed to BAC solutions at various concentrations (0.1%-0.0001%) during a period of 10 minutes. Cells were examined before treatment and 3, 24, 48, and 72 hours later, after reexposure to normal cell culture conditions. Cell number and viability were assessed with crystal violet and 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide colorimetric assays. The expression of the apoptotic marker Apo 2.7, nuclear antigen p53, membrane proteins Fas and Fas ligand, and DNA content was studied by flow cytometry. Morphologic aspects of cell nuclei were analyzed on slides with a nucleic acid-specific dye, 4',6'-diamidino-2-phenylindole dihydrochloride. Cytoskeleton was labeled with a monoclonal anti-pancytokeratin antibody. In addition, apoptosis was measured by DNA electrophoresis assays in agarose gel. RESULTS: Cell exposure to 0.1% and 0.05% BAC induced cell lysis immediately after treatment. All cells (100%) treated with 0.01% BAC died in a delayed manner within 24 hours, with most of the characteristics of apoptosis (chromatin condensation and DNA fragmentation, reduction in cell volume, expression of the apoptotic marker Apo 2.7, and apoptotic changes in DNA content). Aliquots of 0.005%, 0.001%, 0.0005%, and 0.0001% BAC induced growth arrest and apoptotic cell death in a dose-dependent manner between 24 and 72 hours after treatment. The expressions of Fas and p53 did not vary after BAC treatment. Fas ligand was always negative. CONCLUSIONS: These results suggest that BAC induces cell growth arrest and death at a concentration as low as 0.0001%. The mode of BAC-induced cell death is dose-dependent. Cells die by necrosis after BAC treatment at high concentrations and by apoptosis if low concentrations of BAC are applied. This new aspect of in vitro toxicity of BAC could in part explain some ocular surface disorders observed in patients undergoing long-term topical treatments with preservative-containing drugs.  (+info)

Cluster of postinjection abscesses related to corticosteroid injections and use of benzalkonium chloride. (2/234)

Benzalkonium chloride (BC) is an unreliable disinfectant. A matched case-control study and environmental investigation were conducted to determine the cause of and risk factors for a cluster of postinjection abscesses at a private medical clinic where BC was used as a disinfectant. Twenty-eight case-patients who had an abscess at the injection site were matched with 126 control patients who had received an intramuscular injection at the clinic on the same day. Risk factors for abscess development in a multivariable logistic model were corticosteroid injection and being female. All case-patients had received a corticosteroid injection from a multidose vial. Cultures of abscesses from 20 of 23 case-patients grew Pseudomonas aeruginosa. Cultures of BC prepared at the clinic also grew P aeruginosa, suggesting that BC was the source of infection. Injection site cleaning with BC did not appear to be the route of infection since use of BC at the time of injection was not associated with abscess development. A more likely route of infection was injection of contaminated corticosteroid from multidose vials that could have been inoculated with pseudomonads via needle puncture after vial septa were wiped with contaminated BC. Benzalkonium chloride should not be used to clean injection vial septa or injection sites.  (+info)

Using of thin-layer chromatography for identification and quantitative determination of benzalkonium chloride in eye drops. (3/234)

Conditions for thin-layer chromatographic separation of components (therapeutic and auxiliary substances) in selected eye drops have been established and next used for the densitometric determination of benzalkonium chloride content in the drugs.  (+info)

Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group. (4/234)

OBJECTIVES: To study the tolerance and acceptability in Africa of a perinatal intervention to prevent vertical HIV transmission using benzalkonium chloride disinfection. DESIGN: A randomized, double blinded phase II trial. SETTING: Prenatal care units in Abidjan (Cote d'Ivoire) and Bobo-Dioulasso (Burkina Faso). PATIENTS: Women accepting testing and counselling who were seropositive for HIV-1 and under 37 weeks of pregnancy were eligible. A total of 108 women (54 in each group) enrolled from November 1996 to April 1997, with their informed consent. INTERVENTION: Women self administered daily a vaginal suppository of 1% benzalkonium chloride or matched placebo from 36 weeks of pregnancy, and a single intrapartum dose. The neonate was bathed with 1% benzalkonium chloride solution or placebo within 30 minutes after birth. MAIN OUTCOME MEASURES: Adverse events were recorded weekly, with a questionnaire and speculum examination in women through delivery, and examination of the neonate through day 30. The incidence of genital signs and symptoms in the women and cutaneous or ophthalmological events in newborns were compared between groups on an intent to treat basis. RESULTS: The median duration of prepartum treatment was 21 days (range 0-87 days). Compliance was 87% for prepartum and 69% for intrapartum treatment, and 88% for the neonatal bath, without differences between the two groups. In women, the most frequent event was leucorrhoea; the incidence of adverse events did not differ between treatment groups. In children, the incidence of dermatitis and conjunctivitis did not differ between the benzalkonium chloride and placebo groups (p = 0.16 and p = 0.29, respectively). CONCLUSION: Vaginal disinfection with benzalkonium chloride is a feasible and well tolerated intervention in west Africa. Its efficacy in preventing vertical HIV transmission remains to be demonstrated.  (+info)

Emergence of resistance to biocides during differentiation of Acanthamoeba castellanii. (5/234)

A synchronous encystment method was used to study the order of development of resistance of Acanthamoeba castellanii to a range of biocides. The emerging resistance during encystation to short-term exposure to the minimum amoebicidal concentrations of each biocide tested was recorded during the first 36 h of the differentiation process. Hydrochloric acid and moist heat were tested as possible resistance markers. Development of the acid-insoluble, proteincontaining, ectocyst wall and the cellulose endocyst wall was followed by quantification of the acid- and alkali-insoluble residues of cell samples removed from synchronous encystment cultures up to 36 h. Resistance to chemical agents (polyhexamethylene biguanide, benzalkonium chloride, propamidine isethionate, pentamidine isethionate, dibromopropamidine isethionate, hydrogen peroxide) and to moist heat was seen to develop between 14 and 24 h after trophozoites were inoculated into the encystment media. Resistance to hydrochloric acid developed between 0 and 2 h and to chlorhexidine diacetate between 24 and 36 h. Levels of acid-insoluble residues began to increase after 8 h and alkali-insoluble residues (cellulose) were detected after 16 h and coincided with the emergence of resistance to all the agents tested except hydrochloric acid. The results suggest that resistance to the biocides tested probably results largely from the physical barrier of the cyst walls rather than as a consequence of a metabolically dormant cyst.  (+info)

Endocrine cells in the denervated intestine. (6/234)

This study deals with the effects of myenteric denervation of the proximal jejunum on endocrine cell population of the crypt-villus unit, 5 months after treatment with benzalkonium chloride (BAC). Male Wistar albino rats weighing on average 100 g were allocated to two groups: the BAC group - the proximal jejunal serosa was treated with 2 mM BAC for 30 min, and the control group - treated with saline solution (0,9% NaCl). There was a significant reduction in neurone number in the jejunal myenteric plexus of the BAC group and the endocrine cell population (serotoninergic and argyrophilic cells) was significantly increased in this intestine segment. In conclusion, the present findings provide further evidence that the myenteric denervation induced by BAC may lead to the development of a local imbalance of the neurotransmitters, with a consequent induction of enteroendocrine cell (argyrophilic and serotoninergic cells) hyperplasia in the crypt and villus.  (+info)

Low sensitivity of Listeria monocytogenes to quaternary ammonium compounds. (7/234)

Ninety-seven epidemiologically unrelated strains of Listeria monocytogenes were investigated for their sensitivities to quaternary ammonium compounds (benzalkonium chloride and cetrimide). The MICs for seven serogroup 1/2 strains were high. Three came from the environment and four came from food; none were isolated from human or animal samples. All 97 strains carried the mdrL gene, which encodes a multidrug efflux pump, and the orfA gene, a putative transcriptional repressor of mdrL. The absence of plasmids in four of the seven resistant strains and the conservation of resistance after plasmid curing suggested that the resistance genes are not plasmid borne. Moreover, PCR amplification and Southern blot hybridization experiments failed to find genes phylogenetically related to the qacA and smr genes, encoding multidrug efflux systems previously described for the genus Staphylococcus. The high association between nontypeability by phages and the loss of sensitivity to quaternary ammonium compounds are suggestive of an intrinsic resistance due to modifications in the cell wall.  (+info)

In vitro inactivation of Chlamydia trachomatis and of a panel of DNA (HSV-2, CMV, adenovirus, BK virus) and RNA (RSV, enterovirus) viruses by the spermicide benzalkonium chloride. (8/234)

Kinetics of inactivation by the detergent spermicide benzalkonium chloride (BZK) of Chlamydia trachomatis and of a panel of DNA viruses [herpes simplex virus hominis type 2 (HSV-2), cytomegalovirus (CMV), adenovirus (ADV) and BK virus (BKV)] and RNA [respiratory syncytial virus (RSV) and enterovirus (ENV)] were established in accordance with a standardized in vitro protocol. After a 5 min incubation, inactivation of >95% of HSV-2 and CMV was obtained at a concentration of 0.0025% (w/v) (25 Ig/L); concentrations as low as 0.0005%, 0.0050% and 0.0125%, induced a 3.0 log10 reduction in infectivity of HSV-2 and CMV, RSV and ADV, respectively. After a 60 min incubation, concentrations of 0.0125% and 0.050% provided a 3.0 log10 reduction in infectivity of ENV and BKV, respectively. These features indicate that sensitivity to BZK was very high (HSV-2 and CMV) or high (RSV) for enveloped viruses, intermediate (ADV) or low (ENV and BKV) for non-enveloped viruses. Furthermore, BZK had marked antichlamydial activity, showing >99% killing after only a 1 min incubation at a concentration of 0.00125%. BZK demonstrates potent in vitro activity against the majority of microorganisms causing sexually transmitted infectious diseases, including those acting as major genital cofactors of human immunodeficiency virus transmission. These attributes qualify BZK as a particularly attractive candidate for microbicide development.  (+info)

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Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent Label. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride Label. This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal drops or sprays as an excipient ingredient serving as an antimicrobial preservative Label. When used as an ingredient in antiseptic and disinfectant products however, it is an active antimicrobial agent 2.. ...
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TY - JOUR. T1 - Benzalkonium chloride. T2 - A known irritant and novel allergen. AU - Wentworth, Ashley B.. AU - Yiannias, James A.. AU - Davis, Mark D.P.. AU - Killian, Jill M.. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Background Benzalkonium chloride (BAK), a detergent and preservative found in health care and household products, is an established irritant, yet BAK is seldom considered to cause allergic contact dermatitis. We have, however, observed positive patch test reactions more often than is typically reported. From 2001 through 2005 and 2006 through 2010, BAK was among the top 10 most frequent allergens in our standard series. Objective The aim of this study was to review the Mayo Clinic experience from 2000 to 2012 with patch testing to BAK. Methods An electronic patch test database was used to acquire results of patients who underwent patch testing for BAK 0.1% aqueous after it was introduced to the standard series in 2000 until 2012. Previous reports (1998-2000, 2001-2005, 2006-2010) from ...
and pharmacist if you are allergic to olopatadine, benzalkonium chloride, or any other medications. Ask your pharmacist for ... lenses, you should know that olopatadine solution contains benzalkonium chloride, which can be absorbed by soft contact lenses ...
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Lists the various brand names available for medicines containing benzalkonium chloride. Find information on benzalkonium chloride use, treatment, drug class and molecular formula.
TY - JOUR. T1 - Benzalkonium ion sorption to peat and clays. T2 - Relative contributions of ion exchange and van der Waals interactions. AU - Ndabambi, Mlamuli. AU - Kwon, Jung Hwan. PY - 2020/5. Y1 - 2020/5. N2 - Due to their use in various domestic and industrial formulations, benzalkonium compounds have been isolated in many environmental matrices. Sorption to soil components has been shown to play a key role in their environmental fate. Whereas sorption of benzalkonium compounds to soils is attributed to cation exchange and van der Waals forces, the relative contributions of these two mechanisms at environmental levels have not been clearly defined. In this study a previously reported algal toxicity assay-based method was employed to determine the distribution coefficients (Kd) of benzalkonium compounds between water and soil components, at environmental concentrations. Cation exchange capacity corrected Kd values for organic matter and clays were all within one order of magnitude. This ...
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Members of the Pseudomonas family are commonly found in nature, some species are pathogenic for humans, as well as being resistant to multiple disinfectants. Various studies have revealed that benzalkonium chloride (BKC) has an inhibitory effect on many bacteria but it has no significant effect on Pseudomonas aeruginosa. Cetrimide agar medium is recommended for the isolation and enumeration of Ps. aeruginosa in food and environmental samples. However, there are claims that for some food factories and in particular the bottled water industry, the selectivity of this medium is not sufficient. The aim of the current research is the creation of a more selective medium for Ps. aeruginosa with BKC. A total of 28 isolates were isolated with Cetrimide agar from raw water samples and identified using biochemical tests and commercial identification kits. All the bacteria were inoculated in Cetrimide agar plates containing 0 - 625 μg/mL BKC. The Petri dishes were incubated at 37°C and 42°C for 24 h. The results
Controlling the food-borne pathogen Listeria (L.) monocytogenes is of great importance from a food safety perspective, and thus for human health. The consequences of failures in this regard have been exemplified by recent large listeriosis outbreaks in the USA and Europe. It is thus particularly notable that tolerance to quaternary ammonium compounds such as benzalkonium chloride (BC) has been observed in many L. monocytogenes strains. However, the molecular determinants and mechanisms of BC tolerance of L. monocytogenes are still largely unknown. Here we describe Tn6188, a novel transposon in L. monocytogenes conferring tolerance to BC. Tn6188 is related to Tn554 from Staphylococcus (S.) aureus and other Tn554-like transposons such as Tn558, Tn559 and Tn5406 found in various Firmicutes. Tn6188 comprises 5117 bp, is integrated chromosomally within the radC gene and consists of three transposase genes (tnpABC) as well as genes encoding a putative transcriptional regulator and QacH, a small multidrug
Purpose: : To characterize the interactions between antigen presenting cells (APC) and epithelial conjunctival cells (EPC) when exposed to the most common preservative in eye drops, benzalkonium chloride (BAK). Methods: : APC were obtained from a human monocytic leukemia cell line THP-1 and EPC from Wong Kilbourne-derived human conjunctival cells. APC and EPC were separately exposed to subtoxic concentrations of BAK (10-5% for APC and 10-3% for EPC) and PBS for 24 hours. The cytokine production at 24h was measured in supernatants using a human cytokine array (Proteome Profiler, R&D Systems). Then, APC were cultured with the filtered supernatants obtained after stimulation of EPC with BAK. Similarly, EPC were cultured with the filtered supernatant obtained after stimulation of APC. Phenotype modifications were evaluated using flow cytometry and a panel of clusters of differentiation: CD11b, CD11c, CD33 and CD54 for APC; and CD63, CD95 and CD54 for EPC. Results: : Exposure to BAK modified the ...
The mainstay of treatment in a chronic disease like glaucoma is topical medications. Most of these medications need to be preserved with a preservative as mandated by the US FDA. Benzalkonium chloride (BAK) is the most widely employed preservative. It causes corneal and conjunctival damage and leads to various ocular surface disorders (OSD) which affect quality of life of the patients. The causality assessment of BAK has firmly established its role in the patho-physiology of OSD. This is further reinforced by many in vitro and in vivo studies. Chronic use of BAK challenges the basic concept of ocular therapeutics as it is bound to lead to the singular and quite predictable fate i.e. iatrogenic OSD over long term use. Hence, there is a need for newer preservatives or preservative free medications so that ocular surface health is not compromised in the long-term treatment of glaucoma.. ...
Purpose: : To evaluate the antimicrobial efficacy of gatifloxacin with and without benzalkonium chloride (BAK) and unpreserved moxifloxacin against methicillin-resistant Staphylococcus aureus (MRSA). Methods: : Sixty-seven clinical isolates of MRSA were evaluated. Minimum inhibitory concentration (MIC) testing was by microbroth dilution in accordance with the recommended CLSI procedure. Approximately 105 CFU/ml of methicillin resistant S. aureus was added to Mueller-Hinton broth containing two-fold concentration increments of drug. For the evaluation of gatifloxacin with BAK, 2.5 µl of a 10% solution was added to the first well of the plate to give a BAK concentration of 0.125%, and then was serially diluted with the drug; subsequently diluted at 1:2 when adding organisms to each well. Plates were incubated for 18 hours in ambient air and the lowest concentration showing no growth was recorded as the MIC. In separate experiments, the growth of 30 MRSA isolates was tested in appropriate media ...
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Benzalkonium chloride is a mixture of alkylbenzyldimethylammonium chlorides of various even-numbered alkyl chain lengths. It is used as a surfactant. Hydrophobic quaternary amines, like BTC, produce poor peak shape in reversed-phase chromatography due to interaction of quaternary amines with residual silanols. Ideal peak shape can be achieved on reversed-phase anion-exchange columns like Primesep D. Primesep D has a basic group on the surface of silica gel that shields silanols from interacting with quaternary, tertiary, secondary and primary amines. This allows to achieve symmetrical peaks for hydrophobic basic analytes. Compounds need to be hydrophobic enough to get compensation for repulsion effect coming from stationary phase. BTC can be monitored by ELSD and UV. Primesep D will also retain acidic counter-ions of quaternary amines, so simultaneous analysis of hydrophobic basic and hydrophilic basic compounds is possible. ...
My daughter has just been diagnosed with an allergy to a very common chemical called Benzalkonium Chloride. She had multiple reactions to a variety of products that contains this chemical. I am struggling to find support groups or info because this is relatively rare. When she touches a product with the chemical she breaks out in hives ( ex chlorox wipes, bactine, detergants) but when the chemical enters her body ( eye drops, nasal spray) he has an anaphylactic reaction. When i research drug allergies it seems pretty clear cut to just avoid the medicatin but this chemical is in so many things its so very hard to avoid. Any one else have any experience with something like this ...
My daughter has just been diagnosed with an allergy to a very common chemical called Benzalkonium Chloride. She had multiple reactions to a variety of products that contains this chemical. I am struggling to find support groups or info because this is relatively rare. When she touches a product with the chemical she breaks out in hives ( ex chlorox wipes, bactine, detergants) but when the chemical enters her body ( eye drops, nasal spray) he has an anaphylactic reaction. When i research drug allergies it seems pretty clear cut to just avoid the medicatin but this chemical is in so many things its so very hard to avoid. Any one else have any experience with something like this ...
The global benzalkonium chloride market is expected to witness high gains from 2019 to 2025 with ever expanding application scope of BAC on account of its cost effectiveness.
Health Smart Antibacterial Wet Wipes For Hands And Face with NDC 52862-611 is a a human over the counter drug product labeled by International Wholesale Inc. The generic name of Health Smart Antibacterial Wet Wipes For Hands And Face is benzalkonium chloride.
Antibacterial Wet Wipes with NDC 73760-007 is a a human over the counter drug product labeled by Zhejiang Easyclean Daily Chemical Co., Ltd.. The generic name of Antibacterial Wet Wipes is benzalkonium chloride.
More information is available on benzalkonium chloride + light liquid paraffin + triclosan including side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information.
A. B. ENTERPRISES is a renowned manufacturer, supplier, exporter of Benzalkonium Chloride, and more products of Pigment Powder, Pigment Paste & Emulsions, based in Mumbai, Maharashtra, India.
Benzalkonium Chloride - CAS 8001-54-5 - Calbiochem CAS 8001-54-5 Cationic surface-active agent and germicide. Its effects are potentiated in the presence of di-n-butyl esters, such as diisobutyladipate. M.W. ~360. - Find MSDS or SDS, a COA, data sheets and more information.
I think this blog is great!. The pregnancy and benzalkonium chloride pregnancies in women with type 1 diabetes included four therapeutic abortions, two due to major congenital malformations (spina bifida and anencephaly) and two due to chromosomal abnormalities. Proper vitamin and mineral intake is essential, but also try quinine in the form of tonic water. Feels terrible, doesnt it. In general there is no cure chloridee allergies, but there are several types of medications available - both over-the-counter what happens in the first 6 weeks of pregnancy prescription - to help ease and treat annoying symptoms like congestion and runny nose. Not only does it compliment her growing curves in the rear, but it sure does boost the mood when someone essentially can a home pregnancy test give you a false positive you that you look normal from the back. Breast tenderness can also pop up when you start or increase hormonal birth control or from trauma. Using honey as remedy for cough pregnancy and ...
Save on Cold Sore Treatmnt Benz Cmph (benzalkonium chloride camphor) prescription medication with Blink Pharmacy. Same pills. Lower prices. No coupon req.
We,China Suppliers & China Manufacturers, provide our Products catalog2: China Benzalkonium Chloride, China 3-Bromopropionic acid, China 4-Chlorosalicylic acid
We, Somu Group Of Companies is one of the ISO 9001:2004, ISO 14001:2000 and OSHAS 18001 Certified prominent leading Manufacturer, Supplier and Exporter of BENZALKONIUM CHLORIDE ( 50% GEL) based In BTM Layout, Bengaluru, Karnataka, India
8001-54-5 - Benzalkonium chloride [INN:BAN:JAN:NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information.
TY - JOUR. T1 - Does benzalkonium chloride cause cataract?. AU - Brandt, James D. PY - 2003/6/1. Y1 - 2003/6/1. UR - http://www.scopus.com/inward/record.url?scp=0037672756&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0037672756&partnerID=8YFLogxK. U2 - 10.1001/archopht.121.6.892. DO - 10.1001/archopht.121.6.892. M3 - Article. C2 - 12796264. AN - SCOPUS:0037672756. VL - 121. SP - 892. EP - 893. JO - JAMA Ophthalmology. JF - JAMA Ophthalmology. SN - 2168-6165. IS - 6. ER - ...
AVA CHEMICALS PRIVATE LIMITED - Manufacturer, Supplier, Exporter of Benzalkonium Chloride, Chelating Agents, Edta Chemical, DTPA Chemical, HEDP Chemical, HEDP Acid, from Mumbai, Maharashtra, India.
Cap Soft Calcitriol 0.25mcg + Calcium Citrate 425mg + Zinc 20mg + Cap Soft Co-Enzyme Q-10, Eicosapentenoic Acid90, Docosahexaenoic Acid 60, Blister Soft Gel Cap Soft Omega-3 Fatty acids, green Tea Ext., Ginkego Biloba,Ginseng Grape Seed Ext., antioxident, Vitamin, Minerals&Trace Elements Bromfenac Sodium 0.09 % + Chloride Solution Ip 0.01 % Fluorometholone 0.1 % + Benzalkonium Chloride Solution 0.004 % Gatifloxacin O.3% + Benazlkonium Chloride Solution 0.01% Ketoralac Tromethamine 0.5%+Chloride Solution 0,02% Ketorolac 0.5 % + Ofloxacin 0.3 % + Benzalkonium Chloride Solution 0.04 % Moxifloxacin 0.5% With Ketrolac 0.5% E/E Drops Moxifloxacin 5Mg + Chloride Solution 0.05% Naphazoline 0.56% + Cpm 0.01% + Boric Acid 1.25% + Zinc Sulphate 0.12% + Polyvinyl Alcohol 14Mg + Povidone 6Mg + Chlorbutol 5Mg Sodium Carboxymethyl Cellulose 0.5% + Sodium Perborate 0.005% Timolol Maleate 0.5 % + Chloride Solution 0.2 % Tobramycin 0.3% + Chloride Solution 0.04% Tobramycin Dexamethasone 0.3% + Sodium Phosphate ...
The aim of this study is to determine the frequency of quaternary ammonium compound-resistant genes, including qacA/B, qacC/D, qacE, qacΔE1, qacG, qacJ, and β-lactamase genes, including bla CTX-M, bla TEM, bla SHV, bla OXA-23, bla VIM, bla IMP, bla NDM and bla GIM in 51 isolates of carbapenem-resistant Acinetobacter baumannii collected over a period of 2 years and to determine the MIC of chlorhexidine and quaternary ammonium compound-based disinfectant benzalkonium chloride. The qac and bla genes were detected by the PCR method. The MICs were determined using the broth microdilution method. The MIC of benzalkonium chloride was in the range of 4 to 64 µg l−1 and chlorhexidine in the range of 4 to 64 µg l−1. The qacΔE1 gene was detected in 96.07 % (49/51) isolates and qacE in 31.37 % (16/51), qacG in 23.52 % (12/51) and qacA/B in 13.72 % (7/51). The qacC/D genes and qacJ were not found in any of these strains in this study. The frequency of bla genes was as follows: 84.31 % (43/51) for bla OXA-23
Viroxyn Professional is specially formulated for the treatment of cold sores. Bactine is an antiseptic liquid with a broad range of uses on minor cuts, stings and burns. But many users of Viroxyn have correctly pointed out that the active ingredient is the same in both products - Benzalkonium Chloride.. Viroxyn usually retails for around $50 for three small vials, while Bactine is much much cheaper, at around $6 for a 120ml (4 oz) bottle.. Click here to read our review of Bactine. So then, how do these two products compare?. It is true that Benzalkonium Chloride is the active ingredient in both Viroxyn and Bactine, and that it is found in the exact same percentage 0.13%. In fact, Benzalkonium Chloride is found in many generic antiseptic wipes and liquids. So its natural for customers to be skeptical about the high price of Viroxyn.. There are a couple of important differences though. Viroxyn also contains Benzocaine, which helps to reduce the pain of cold sore outbreaks. Also, it contains ...
ammonium sulfate hammer mill Influence of benzalkonium chloride on the dissolution rate behavior,ammonium sulfate hammer mill,, normal pellets (1) in i;( sodium cholate, 0 I M phosphate buffer, and 0250 benzalkonium chloride at pH 80 Key: c h = 0 00: A, 03; and +, 11 mglml, size reduction by a hammer mill Hammer mill-particle size reductio.hammer crusher for granulating solid aluminum ...
Roccal-D is a disinfectant manufactured by Pfizer that is used in many animal care facilities and some biological laboratories. It is effective against bacteria including Mycoplasma, Streptococcus, Staphylococcus, E. coli, and Salmonella. It also destroys viruses including canine parvovirus, parainfluenza-3 and pseudorabies. Roccal was originally produced by Winthrop Laboratories. Its active ingredients include quaternary ammonium compounds from the family of benzalkonium chlorides and didecyldimethylammonium chloride. These compounds are nitrogenous cationic surface active agents. Benzalkonium chloride is a mixture of alkylbenzyl dimethylammonium chlorides of various alkyl chain lengths. The greatest bactericidal activity is associated with the C12-C14 alkyl derivatives. The current formulation of Roccal also includes tributyltin oxide ...
Product Features N,N-4,4-diphenylmethyene bismaleimide(BMI) can give the material outstanding mechanical properties and high electrical insulation at high and low temperature (-200℃~260℃). The Properties, abrasion resistance, aging resistance and chemical corrosion resistance, radiation resistance, volatile properties in high vacuum and excellent. Adhesion, moisture resistance and oil-free self-lubricity, is a variety of polymer materials and new rubber excellent modifier, It can also be used as coupling agent and curing agent of other polymer compounds. Good compatibility with various fillers, with each other the fibers have good wettability, adhesion and coverage. In special polymer materials, easy to process molding. Can be molded, la.... ...
3M Neutral Quat Disinfectant Cleaner Concentrate N23 information about active ingredients, pharmaceutical forms and doses by 3M, 3M Neutral Quat Disinfectant Cleaner Concentrate N23 indications, usages and related health products lists
Sprawdź ile zapłacisz za lek lidocaine/benzalkonium spray w aptece, znajdź tańsze zamienniki leku. Określ swoje uprawnienia i sprawdź jakie zniżki Ci przysługują.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
CAS No. 8001-54-5. Consists of Benzyl (dodecyl) dimethyl ammonium chloride (approx. 65%) and Benzyl (tetradecyl) dimethyl ammonium chloride (approx. 35%). Contains approx. 95% active ingredients.. Packaging sizes:. 50kg drum - Item number: 8560002. Documentation and services:. ...
quaternary ammonium compound definition. Explain quaternary ammonium compound. What is quaternary ammonium compound? quaternary ammonium compound meaning. quaternary ammonium compound sense. quaternary ammonium compound FAQ. quaternary ammonium compound synonyms.
Didecyl Dimethyl Ammonium Chloride suppliers provide Benzalkonium Chloride, HexadecylTrimethylAmmonium Bromide with factory price
A synergistic cleaning composition has been discovered comprising an aqueous solution a quaternary ammonium compound component; a nonionic surfactant component; and a glycol ether solvent. Surprisingly, the combination of the quaternary ammonium compound component, the nonionic surfactant component, and glycol ether solvent provides a synergistic effect where the cleaning composition functions with a low level of quaternary ammonium compound component while still maintaining at least one of the following desirable properties, as follows: an acceptable cleaning efficacy; a low level irritation or toxicity profile; and/or a broad spectrum antimicrobial activity.
Hedayatfar, A., Hashemi, H., Asgari, S., Chee, S.-P. (2014). Comparison of efficacy and ocular surface toxicity of topical preservative-free methylprednisolone and preserved prednisolone in the treatment of acute anterior uveitis. Cornea 33 (4) : 366-372. [email protected] Repository. https://doi.org/10.1097/ICO. ...
Stearalkonium chloride is a type of benzalkonium chloride which is used as an anti-static agent, a surfactant and an antimicrobial. It is an ingredient in some cosmetics and hair care products, particularly conditioners. It was originally designed by the fabric industry for use as a fabric softener. Toxicology studies have determined that stearalkonium chloride is safe and non-toxic at the concentrations typically used in cosmetic products (0.1 to 5%). At higher concentrations (25% solution), it has been shown to cause minor skin and eye irritation in animals. Benzalkonium chloride Polyaminopropyl biguanide, an alternative preservative for contact lens solutions Ethylenediaminetetraacetic acid Triclosan Thiomersal Stearyl dimethyl benzyl ammonium chloride, chemicalland21.com Stearalkonium chloride, Household Products Database Final Report on the Safety Assessment of Stearalkonium Chloride. International Journal of Toxicology. 1 (2): 57-69. 1982. doi:10.3109/10915818209013147 ...
Define quaternary ammonium compound: any of numerous strong bases and their salts derived from ammonium by replacement of the hydrogen atoms with…
Fibrous cellulose materials useful in the manufacture of soft, absorbent paper products such as paper towels, facial tissues, and toilet tissue are disclosed. The paper products contain a vegetable oil based quaternary ammonium chemical softening compound. Examples of preferred vegetable oil based quaternary ammonium chemical softening compounds include diester di(oleyl)dimethyl ammonium chloride (DEDODMAC) (i.e., di(octadec-z-9-eneoyloxyethyl)dimethyl ammonium chloride) derived from canola oil and/or high oleic safflower oil. Variables that need to be adjusted to maximize the fluidity of vegetable oil based acyl groups include the cis/trans isomer ratio or the Iodine Value (IV) of the fatty acyl groups. The tissue softness is further enhanced by controlling the purity of the fatty acyl groups and the di-substituted versus mono-substituted long chain hydrocarbyl substituent ratio in the quaternary ammonium compounds.
Ark-Klens is a bird safe brilliant bird disinfectant and cleanser. Its a really good cleanser for wiping down surfaces, non-scented to it doesnt put the birds off. Kills psittacosis, flu viruses (and many others) and E.coli and Salmonella. Its been used on vet tables for years, is recommended by UFAW for bird tables - sold by the RSPB - you cant get better. A bottle goes a long way so its economical.. This is a blend of benzalkonium chloride (quaternary ammonium compounds or QAC´s) specially selected for safety of use. This family of chemicals are powerful disinfectants with an additional detergent and deodorising action.. At the recommended concentrations ARK-KLENS is non-corrosive, it is bactericidal against a wide range of gram negative and gram positive bacteria, some viruses and some fungi are also susceptible. This makes ARK-KLENS suitable for disinfection of the birds or animals environment such as cages, kennels, and food and water bowls etc. It can also be used safely as a ...
Biocides, primarily those containing quaternary ammonium compounds (QAC), are heavily used in hospital environments and various industries (e.g., food, water, cosmetic). To date, little attention has been paid to potential implications of QAC use in the emergence of antibiotic resistance, especially fluoroquinolone-resistant bacteria in patients and in the environment. QAC-induced overexpression of efflux pumps can lead to: cross resistance with fluoroquinolones mediated by multidrug efflux pumps; stress response facilitating mutation in the Quinolone Resistance Determining Region; and biofilm formation increasing the risk of transfer of mobile genetic elements carrying fluoroquinolone or QAC resistance determinants. By following the European Biocidal Product Regulation, manufacturers of QAC are required to ensure that their QAC-based biocidal products are safe and will not contribute to emerging bacterial resistance.. ...
99035-72-0 - Quaternary ammonium compounds, benzyl-C10-16-alkylbis(hydroxyethyl), chlorides - Searchable synonyms, formulas, resource links, and other chemical information.
BOCARE DISINFECTANT 20L is a clear green, perfumed, mildly alkaline germicidal liquid disinfectant/detergent containing a QAC type disinfectant (Alkyl Benzyl Dimethyl Ammonium Chloride - known as Benzalkonium Chloride). PRODUCT FEATURES Contains an effective surface active agent which enhances the ability of the bactericide to penetrate to the bacteria. Non-volatile and stable in storage. Pleasant fragrance which leaves a lingering odour. Effec
Ocular toxicity resulting from chemicals in eye drops is common. Preservatives such as benzalkonium chloride (BAC) and related quaternary ammonium salts have been shown to play an important part in these reactions.1 The symptoms can range from mild injection and itching to severe conjunctival reactions. The term pseudopemphigoid has been applied to drug-induced cicatrising conjunctivitis.2-5 We present a patient who developed drug-induced granulomatous cicatrising conjunctivitis secondary to glaucoma drops.. ...
addition kromoglitsievoy acid at a dose of 20 mg, a member of the drug include water for injection, benzalkonium chloride, boric acid and disodium edetate.Selection of such a combination is required to maximize efficacy and to reach therapeutic effect with minimal side effects.Lekrolin (eye drops), whose instructions must contain details of this medication, are available in a dropper-bottles (10 ml) or tubes (0.25 ml), it was convenient to use it.Of course, it is absolutely sterile product, which has a certain period of time and storage conditions.Therefore, if the course of treatment prescribed by a doctor, not so long, it is best to buy a tube of small volume, as undesirable use of the drug after prolonged storage at home.In view of the medicament Lekrolin - eye drops - is a clear solution without suspended solids and impurities, but may have a slightly yellowish tint.. ...
Murine should not be used if there is an eye condition characterised by continued redness, pain or blurring of vision.. Murine should not be used if there is raised pressure inside the eyeball (glaucoma), damage to the corneas, inflammation of the iris (acute iritis) or any other serious eye disease.. If there is any eye pain, vision changes, continued redness or irritation of the eye, or if the condition worsens or persists for more than 24 hours, use of the product should be discontinued and the doctor or pharmacist should be informed.. Discontinue use prior to use of anaesthetics which sensitise the myocardium to sympathomimetics (e.g. cyclopropane, halothane).. As with other sympathomimetics, use with caution in the presence of hypertension, diabetes, hyperthyroidism, cardiovascular abnormalities and arteriosclerosis.. Contains benzalkonium chloride which may cause eye irritation. Avoid contact with soft contact lenses; remove contact lenses prior to application and wait at least 15 minutes ...
Disinfectants, such as benzalkonium chloride (BAC), are commonly used to control Listeria monocytogenes and other pathogens in food processing plants. Prior studies have demonstrated that the resistance to BAC of L. monocytogenes was associated with the prolonged survival of three strains of molecular serotype 1/2a in an Iberian pork processing plant. Because survival in such environments is relat ...
HKU Facualty of Medicine*, Singapore National Environmental Agency*, confirm the usage of Benzalkonium Chloride, the key ingredient of this sanitiser, effectively disables the infectivity of Covid-19. This ingredient has been widely used as medical disinfectants in lozenges and eyedrops. Lemon Myrtle is naturally antib
Inactivation of human immunodeficiency virus type 1 in tissue culture fluid and in genital secretions by the spermicide benzalkonium chloride.
A contact lens cleaning, storing and wetting solution is provided for cleaning, storing and wetting flexible silicone contact lenses. The solution comprises a poly(oxyethylene)- poly(oxypropylene) block copolymer having a molecular weight between about 1,900 and 15,500, a water solubility in excess of about 10 grams per 100 ml., a cloud point in 1% aqueous solution above about 30 DEG C., and a Foam Height in excess of 30 mm; a microbial growth inhibitor, such as benzalkonium chloride; purified water; and a sufficient amount of at least one essentially neutral, water-soluble compatible salt to provide a solution salt content equivalent to about 0.5 to 1.8% sodium chloride. The solution can also contain disodium or trisodium ethylenediamine tetraacetate and a polymeric viscosity building agent, if desired.
INTRODUCTION. In a recent report by Nishikawa et al. (1), the microorganisms isolated from the soil exhibited resistance towards benzalkonium chloride. Russel and co-workers have (2) proposed two possible mechanisms for such resistance: the intrinsic and acquired resistances. The intrinsic resistance related to the structural and chemical composition of the outer layers of the cells, which may provide an effective barrier to the entry of antibacterial agents. The acquired resistance results from genetic changes in the bacterial cell and arises either by mutation or by the acquisition of genetic material from another cell. Extensive investigations in the field of Schiff bases have been reported (3-5). Antimicrobial and antifungal activities of various Schiff bases ...
Rengjør hodebunnen, ved å bruke 1 av de 4 sjampoene fra Medline Organic først. Påfør 3-5 ml Meso Hair Solution for å dekke hele hodebunnen en gang i uken. Før Meso Roller i hodebunnen . Behandlingsvarighet : 2 økter hver dag første 14 dager, deretter hver 15. dag i 3 måneder. For å vedlikeholde resultatet, må produktet brukes 1 gang pr måned. Resultatet kan sees etter 3 måneder. Unngå kontakt med øynene. Ved kontakt med øynene skyll straks.. 3 Vekstfaktorer, Biomimetic Peptide,. 14 Vitaminer,. 23 Aminosyrer,. 5 Minerals,. 4 Koenzymer,. 3 nukleinsyrer,. 2 Antioksidanter. Innhold: Aqua (Water), Sodium Dihydrogenphosphate Dihydrate, Potassium Chloride, Sodium Hydroxide, Calcium Chloride, Glutamine, Magnesium Sulfate, Aminobutyric Acid, Benzalkonium Chloride, Sodium Ascorbate, Alanine, Lysine , Arginine, Valine, Histidine, Leucine, Threonine, Isoleucine, Tryptophan, Phenylalanine, Tyrosine, Glycine, Serine, Adenosine Cyclic Phosphate, Aspartic Acid, Cytosine, Cystine, Glutathione, ...
Antibacterials may be divided into two groups according to their speed of action and residue production: The first group contains those that act rapidly to destroy bacteria, but quickly disappear (by evaporation or breakdown) and leave no active residue behind (referred to as non-residue-producing). Examples of this type are the alcohols, chlorine, peroxides, and aldehydes. The second group consists mostly of newer compounds that leave long-acting residues on the surface to be disinfected and thus have a prolonged action (referred to as residue-producing). Common examples of this group are triclosan, triclocarban, and benzalkonium chloride. How common are antibacterials in consumer products?. All products that claim to kill bacteria and/or viruses have some kind of antibacterial agent. Alcohols, chlorine and peroxides have been used for many decades in health-care and cleaning products. Within the past two decades, the residue-producing antibacterials , once used almost exclusively in health ...
March 20, 2015: Meeting to obtain clarification on the human pharmacokinetic maximal use trial (MusT) as outlined in the October 15, 2015 FDA General Advice letter and the Memorandum of Meeting Minutes from the meeting held between Lonza America Inc., and the FDA on May 6, 2015; and 2) discussing the process of requesting a time extension for completion of the MUsT and other safety data required for support of a Generally Recognized as Safe (GRAS) listing for benzethonium chloride and benzalkonium chloride. ...
Clinical formulations with integrity-thats what The Ordinary is about. Created to celebrate truth, veracity, and reliability, the beauty company is focused on advanced functional beauty while honestly communicating its products to its consumers. The end goal? Bringing to market effective, well-known technologies at reasonable prices. As part of DECIEMs brands, The Ordinary is also free of Parabens, Sulphates, Mineral Oil, Methylchloroisothiazolinone, Methylisothiazolinone, Animal Oils, Benzalkonium Chloride, Coal Tar Dyes, Formaldehyde, Mercury, and Oxybenzone and does not test on animals. All you need is to try out one of their bestselling products, extremely affordable and effective skincare products and youll realize what makes The Ordinary, extraordinary.. ...
12 chemical principles 69pounds formed by nonenzymatic hydrolysis, is the term associated with one important exception: Diquat lacks the potential to participate in care as appropriate. Injury by metabolites at distant sites toxic metabolites of biotransformation and detoxification of products to determine medications that can be managed by the manufacturer of indinavir found that the usual concerns about changes in illness identifying release chemical weapons (cw), however involve a physical assault rather than about him or her to take temperature of 38c (190f) or above. C: Manual of nursing practice, eliopoulos. Many states also require looking at these persons. Avoid exercising in extreme temperatures). Also enhances feeling of fullness and increased volume of csf in a nonintrusive manner. Benzalkonium chloride may decrease the potential for same. Cas are weak acids has a very large doses relative to their sites of some men. T a b l e s many adults overdose with a sense of ownership in ...
Stable aqueous compositions of silane quaternary ammonium compounds are provided by diluting an alkanol solution of the silane quaternary ammonium compound in water with at least one nonionic surfacta
Arquad C-35, Cocotrimethylammonium chloride, Quaternary ammonium compounds Alkyltrimethyl, Arquad C-35 is a quaternary ammonium compound - Cocotrimethylammonium chloride.
The public activities coordination tool (PACT) provides an overview of the substance-specific activities that authorities are working on under REACH and the CLP Regulation. These activities are being carried out in line with ECHAs Integrated Regulatory Strategy.. PACT provides up-to-date information on the activities planned, ongoing or completed by ECHA and/or MSCAs for a given substance in the following areas:. ...
I have burning when i pee and i have vaginal irritation no foul odors and a white discharge no smells i thought maybe it was a yeast infection so i bought a otc yeast medication but no luck and i cant ...
List of causes of Pregnancy symptoms and Vaginal irritation, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
List of 65 causes for Aching joints and Vaginal irritation, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Vaginal irritation can be annoying and at the same time embarrassment. Ladies, youll understand this better if you have been having vaginal discomfort.
Pac-Kit Crushable Sting Relief Swabs temporarily relieves pain and itching resulting from insect bites and stings; crushable; single-dose plastic ampules with gauze applicator tip; cntains 2% lidocaine, 1% menthol, 13% benzalkonium
Antibacterial Surface Cleanser Bactericidal and Virucidal cleanser. Can be used in food preparation areas.Leaves surfaces hygienically clean. Ideal for use on: Glass Plastic Marble Steel Enameled surfaces Based on Quaternary Ammonium Compounds.Does not contain ethanol, aldehydes or phenols.
File Title: A study of the lipids of Pseudomonas aeruginosa sensitive and resistant to chloramphenicol and quaternary ammonium compound ...
Due to potential contamination with quaternary ammonium compounds, United Pet Group has voluntarily recalled several brands of its rawhide dog chew products.
The present invention relates to a personal care product containing a mixture of at least one personal care ingredient and one diester quaternary ammonium compound with a pH between 4.0 and 10.0 and a viscosity between 100 and 300,000 cps, and the method of making the personal care product diester tertiary amines and quats are also described.
Summary of Facts and Submissions. I. This appeal is from the decision of the Opposition Division to revoke the European patent No. 0 900 260 relating to a high di(alkyl fatty ester) quaternary ammonium compound from trialkanol amine.. II. Six oppositions had been filed, inter alia, on the grounds of Articles (100(a) and (c) EPC), in particular for lack of novelty (Article 54(1)(2) EPC) and inventive step (Article 56 EPC) and added subject-matter (Article 123(2) EPC). The opponents relied, inter alia, on the following document:. (R1) WO-A-91/01295.. III. The Opposition Division had eventually to decide on the main request as filed prior to oral proceedings and a new auxiliary request filed during oral proceedings before the Opposition Division.. In its decision the Opposition Division found that the subject-matter according to the main request was not novel and the subject-matter of the auxiliary request did not involve an inventive step.. IV. The proprietor (hereinafter appellant) filed an ...
AZASITE (Azithromycin) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
Thrive Market offers a wide selection of products for all diet types and needs, including many delicious, preservative free items.
Thrive Market offers a wide selection of products for all diet types and needs, including many delicious, preservative free items.
BZK is FDA-approved as an antiseptic and can be found in disinfecting and skin-prep solutions. Learn more about its advantages here.
Drug information for Full Care BZK Towelette by Shaoxing Fuqing Health Products Co., Ltd.. Includes: facts, uses, warnings, directions and more.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Free Becks Wrench Bottle Opener If you join now, well send a free Becks Wrench Bottle Opener and future goodies to the address you provide here. CA and TX residents not eligible for this promotion. http://www.beckskeyclub.com/BKC/2008/Acq/Register2.aspx ...
chains in the Genus database with same CATH superfamily 2XS3 A; 1GXD A; 4QKZ A; 3HBV P; 4DD8 A; 1JIZ A; 3K7L A; 2XS4 A; 1G9K A; 1BZS A; 1GO7 P; 3O64 A; 1AF0 A; 1OM8 A; 1IAE A; 4WKE A; 4IUW A; 5D7W A; 1UTT A; 4GWN A; 2E3X A; 1GE6 A; 1ZS0 A; 1BIW A; 1MNC A; 1SU3 A; 5LAB A; 2SRT A; 1R1J A; 3N2U A; 1EUB A; 4FU4 A; 4PKR A; 4H82 A; 3LJG A; 1PWV A; 1OMJ A; 3EDI A; 3RTS A; 1BQO A; 1G4K A; 1XUC A; 4XM8 A; 1EB6 A; 4HX3 A; 5I12 A; 1GE7 A; 4DV8 A; 2W14 A; 1XFV A; 1B8Y A; 2MZI A; 1FBL A; 4A7B A; 3AIG A; 5CZM A; 1XFZ A; 3I7I A; 1MMB A; 4FXY P; 4L6T A; 3KMC A; 3EWJ A; 1MMP A; 1QIB A; 1PWP A; 1JIW P; 1BKC E; 1OO9 A; 1JJ9 A; 1PWU A; 3NX7 A; 2FV5 A; 1O0Q A; 2W0D A; 1BSW A; 2W15 A; 4JPA A; 3LJZ A; 5I3M A; 1HOV A; 1RMZ A; 1BUV M; 1IAA A; 3V96 B; 2OXW A; 4XCT A; 3LMC A; 4XBH A; 1ZXV A; 2DW2 A; 1SLM A; 3B92 A; 2D1N A; 4WK7 A; 2DDY A; 4WZV A; 1CK7 A; 3F17 A; 4CTH A; 1I76 A; 1OM6 A; 2WO8 A; 4FVL A; 2HU6 A; 3LQ0 A; 1GO8 P; 4H49 A; 3WV1 A; 2POJ A; 4R3V A; 3VI1 A; 3LIR A; 1YQY A; 5D1S A; 4GR3 A; 1Y0V A; 3DPE A; 1CQR A; ...
Dr. Chang is an amazing surgeon with exceptional bedside manner. He went above and beyond to help me achieve my desired results. I had a mommy makeover and my results exceeded my expectations. I highly recommend his practice.. - RealSelf. ...
Dr. Chang is an amazing surgeon with exceptional bedside manner. He went above and beyond to help me achieve my desired results. I had a mommy makeover and my results exceeded my expectations. I highly recommend his practice.. - RealSelf. ...
Quaternary ammonium compounds ("quats"), such as benzalkonium chloride, are a large group of related compounds. Some ... Occasionally, chlorine-releasing compounds and their salts are included in this group. Frequently, a concentration of < 1 ppm ... Chlorine and oxygen are strong oxidizers, so their compounds figure heavily here. Electrolyzed water or "Anolyte" is an ... García, MR; Cabo, ML (June 2018). "Optimization of E. coli Inactivation by Benzalkonium Chloride Reveals the Importance of ...
These compounds are nitrogenous cationic surface active agents. Benzalkonium chloride is a mixture of alkylbenzyl ... Its active ingredients include quaternary ammonium compounds from the family of benzalkonium chlorides and ...
Benzalkonium chloride, stearalkonium chloride, and cetrimonium are all quaternary ammonium compounds containing nitrogen. The ... This is evidenced by a broad variety of new classes of compounds that have been prepared and studied in the past few years. ... Polymer quaternary ammonium compounds containing nitrogen induce cell death through electrostatic interactions and the ... Optimal antimicrobial activity is generally seen in quaternary ammonium compounds with a long chain length, containing 8-18 ...
"TOXNET Benzalkonium Chloride Compounds". "Haz-Map Benzalkonium Chloride". "NIOSH ICSC Benzalkonium Chloride". Archived from the ... Benzalkonium Chloride ToxNet Human Safety Database - Benzalkonium Chloride Compounds Recognition and Management of Pesticide ... Benzalkonium chloride is a mainstay of phase-transfer catalysis, an important technology in the synthesis of organic compounds ... Depending on purity, benzalkonium chloride ranges from colourless to a pale yellow (impure). Benzalkonium chloride is readily ...
... benzalkonium, 0.5 - 4% chlorhexidine, 0.1 - 2% octenidine solutions. Others are generally not applicable as safe antiseptics, ... non-quaternary compounds, such as chlorhexidine, glucoprotamine, octenidine dihydrochloride etc.), strong oxidizers, such as ... such as benzalkonium chloride, cetyl trimethylammonium bromide or chloride, didecyldimethylammonium chloride, cetylpyridinium ... lactic acid and salicylic acid some phenolic compounds, such as hexachlorophene, triclosan and Dibromol, and cationic ...
Triclosan and triclocarban are the most common compounds used as antibacterials in soaps. However, other common antibacterial ... ingredients in soaps include benzalkonium chloride, benzethonium chloride, and chloroxylenol. Claims that antibacterial soap is ...
Organic compounds containing hydrophilic groups at both ends of the molecule are called bolaamphiphilic. The micelles they form ... Some typical members of this group are: sodium dodecyl sulfate (anionic), benzalkonium chloride (cationic), cocamidopropyl ... An amphiphile (a.k.a. amphipath; from the Greek αμφις, amphis: both and φιλíα, philia: love, friendship) is a chemical compound ... Such a compound is called amphiphilic or amphipathic. Common amphiphilic substances are soaps, detergents, and lipoproteins. ...
In 2011, several compounds (antifungals, fungicides, and biocides) where shown to effectively inhibit the growth of P. ... destructans including benzalkonium chloride, chloroacetoxyquinoline, chloroxine, ciclopirox olamine, econazole, phenylmercuric ... P. destructans can tolerate elevated levels of environmental inhibitory sulfur compounds (cysteine, sulfite, and sulfide), grow ... A recent study (2014) identified several volatile organic compounds (benzaldehyde, benzothiazole, decanal, nonanal, N,N- ...
The usual concentration in these products is 0.01% (w/w). However, it isn't known as a potent bactericidal compound, mainly ... Even though cetalkonium chloride is belongs to the family of benzalkonium chloride, the ophthalmic use of cetalkonium chloride ... For example, US and European pharmacopeias enforce suppliers of benzalkonium chloride to limit the amount of cetalkonium ... Cetalkonium chloride (CKC) is a quaternary ammonium compound of the alkyl-benzyldimethylammonium chloride family, the alkyl ...
Quaternary ammonium compoundsEdit. Quaternary ammonium compounds ("quats"), such as benzalkonium chloride, are a large group of ... Inorganic compoundsEdit. ChlorineEdit. This group comprises aqueous solution of chlorine, hypochlorite, or hypochlorous acid. ... Occasionally, chlorine-releasing compounds and their salts are included in this group. Frequently, a concentration of , 1 ppm ... Alcohol and alcohol plus Quaternary ammonium cation based compounds comprise a class of proven surface sanitizers and ...
Quaternary ammonium compounds have also been shown to have antimicrobial activity. Certain quaternary ammonium compounds, ... A typical synthesis is for benzalkonium chloride from a long-chain alkyldimethylamine and benzyl chloride: CH3(CH2)nN(CH3)2 + ... Quaternary ammonium compounds are prepared by the alkylation of tertiary amines with a halocarbon. In older literature this is ... Quaternary ammonium compounds are cationic detergents, as well as disinfectants, and as such can be used to remove organic ...
In addition, several compounds of natural origin have also shown in vitro antiparasitic activity: the polyphenols mangiferin ... Bath treatments consisting of a combination of benzalkonium chloride and bronopol have also proved to be effective in reducing ... Several compounds of well-known antiprotozoal activity, including niclosamide, oxyclozanide, bithionol sulfoxide, toltrazuril, ... Other studies investigating the in vitro effects of several new synthetic compounds, including 2 naphthyridines, 2 ...
Compounds such as glycerol may be added to prevent drying of the skin. Some versions contain fragrances; however, these are ... Where alcohol sanitizers utilize 62%, or higher, alcohol by weight, only 0.1 to 0.13% of benzalkonium chloride by weight ... Non-alcohol based versions typically contain benzalkonium chloride or triclosan; but are less effective than alcohol-based ones ... Some hand sanitizer products use agents other than alcohol to kill microorganisms, such as povidone-iodine, benzalkonium ...
"PubChem Compound. Retrieved 6 March 2014.. *^ Sanders KM, Zhu MH, Britton F, Koh SD, Ward SM (February 2012). "Anoctamins and ... Since carbachol is poorly absorbed through topical administration, benzalkonium chloride is mixed in to promote absorption.[2] ... Carbachol is a choline carbamate and a positively charged quaternary ammonium compound.[2] It is not well absorbed in the ...
Benzalkonium chloride is commonly used in oil field industry. In oil refineries, hydrogen sulfide can corrode steels so it is ... Compounds derived from tannic acid or zinc salts of organonitrogens (e.g. Alcophor 827) can be used together with anticorrosive ... A corrosion inhibitor is a chemical compound that, when added to a liquid or gas, decreases the corrosion rate of a material, ...
... Antibacterial Surface Cleanser and Dettol Antibacterial Wipes contain the active ingredient benzalkonium chloride. ... an aromatic chemical compound. Chloroxylenol comprises 4.8% of Dettol's total admixture, with the rest made up of pine oil, ...
Dial replaced these ingredients with benzalkonium chloride (for bar soaps) and benzethonium chloride (for liquid hand soaps). ... a synthetic antibacterial compound. Dial became the leading deodorant soap brand in the U.S. From 1953 until the mid-1990s, ... In its 2016 ruling, the FDA also stated that it is deferring the final rule on benzalkonium chloride, benzethonium chloride and ...
... s are compounds, mixtures, or materials that block or absorb ultraviolet (UV) light. One of the major applications of ... Camphor benzalkonium methosulfate (CBM) The use of UV filters has increased recently due to growing concern about UV radiation ... UV classifications include UVA (320-400 nm), UVB (290-320 nm) and UVC (200-280 nm). UV-absorbing compounds are used not only in ... Inorganic UV-filters (i.e. TiO2) can also generate ROS, another compound toxic for marine phytoplankton. UV filters have shown ...
In the United States, its use has been superseded by other agents (e.g., povidone iodine, benzalkonium chloride, chloroxylenol ... is an organomercuric disodium salt compound used as a topical antiseptic for minor cuts and scrapes and as a biological dye. ... "Aqueous solution of benzalkonium chloride and lidocaine hydrochloride") play on the brand recognition history of Mercurochrome ... "Quantitative and Qualitative Analysis of Mercury Compounds in the List". Federal Food, Drug, and Cosmetic Act (FD&C Act). U.S. ...
It was once commonly used as a topical solution for disinfecting wounds, but as with all organomercury compounds it is highly ... "Antifungal effect of ophthalmic preservatives phenylmercuric nitrate and benzalkonium chloride on ocular pathogenic filamentous ... Phenylmercuric nitrate is an organomercury compound with powerful antiseptic and antifungal effects. ...
Chemical compounds used to kill fungus include: Contents: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z See also ... azoxystrobin barium polysulfide benalaxyl benalaxyl-M benodanil benomyl benquinox bentaluron benthiavalicarb benzalkonium ... Organic compound List of biomolecules List of minerals Polyatomic ions List of elements by name List of organic compounds List ... of inorganic compounds [Prevention and treatment of mold in library collections with an emphasis on tropical climates: A RAMP ...
Takeoka GR, Dao LT, Wong RY, Harden LA (September 2005). "Identification of benzalkonium chloride in commercial grapefruit seed ... Chemistry of Natural Compounds. 18: 445-7. doi:10.1007/BF00579640.. ...
"Quantitative and Qualitative Analysis of Mercury Compounds in the List". Federal Food, Drug, and Cosmetic Act (FD&C Act). U.S. ... In the United States, its use has been superseded by other agents (e.g., povidone iodine, benzalkonium chloride, chloroxylenol ... Merbromin is an organomercuric disodium salt compound and a fluorescein. Readily available in most countries, it is no longer ... Within the United States, products such as Humco Mercuroclear ("Aqueous solution of benzalkonium chloride and lidocaine ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... Silver nitrate is an inorganic compound with chemical formula AgNO. 3. This compound is a versatile precursor to many other ... "Silver (metal dust and soluble compounds, as Ag)". Immediately Dangerous to Life and Health Concentrations (IDLH). National ... Seidell, Atherton; Linke, William F. (1919). Solubilities of Inorganic and Organic Compounds (2nd ed.). New York City: D. Van ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... After continued exposure to antibiotics, bacteria may evolve to the point where they are no longer harmed by these compounds. ... Polyhexanide (polyhexamethylene biguanide, PHMB) is an antimicrobial compound suitable for clinical use in critically colonized ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... Isopropyl alcohol (IUPAC name propan-2-ol; commonly called isopropanol) is a compound with the chemical formula CH3CHOHCH3. It ... Isopropyl alcohol dissolves a wide range of non-polar compounds. It also evaporates quickly, leaves nearly zero oil traces, ... Mirafzal, Gholam A; Baumgarten, Henry E (1988). "Control of peroxidizable compounds: An addendum". Journal of Chemical ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... Decomposition is catalysed by various compounds, including most transition metals and their compounds (e.g. manganese dioxide, ... This degrades organic compounds, including those that are ordinarily robust, such as aromatic or halogenated compounds.[55] It ... Hydrogen peroxide is a chemical compound with the formula H. 2O. 2. In its pure form, it is a pale blue, clear liquid, slightly ...
Fatty acid esters of polyhydroxy compounds[edit]. Fatty acid esters of glycerol[edit]. *Glycerol monostearate ... Permanently charged quaternary ammonium salts: cetrimonium bromide (CTAB), cetylpyridinium chloride (CPC), benzalkonium ... Surfactants are compounds that lower the surface tension (or interfacial tension) between two liquids, between a gas and a ... The compounds that coat a micelle are typically amphiphilic in nature, meaning that micelles may be stable either as droplets ...
It is a basic compound that is most active with an alkaline reaction.[2] It is also a thermostable compound that is soluble in ... The compound is then isolated and purified from the bacterium.[23] DNA binding[edit]. Aminoglycosides such as neomycin are ... Standard grade neomycin is composed of a number of related compounds including neomycin A (neamine), neomycin B (framycetin), ... neomycin C, and a few minor compounds found in much lower quantities. Neomycin B is the most active component in neomycin ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... However, cation-active compounds cause local irritation and are extremely poisonous when administered parenterally.[5] ...
... is an organic compound with local anaesthetic, antiseptic and anthelmintic properties.[1] ...
... solutions often contain preservatives such as benzalkonium chloride and benzyl alcohol. Preservative-free products ... These compounds are of particular interest to contact lens manufacturers and prescribing optometrists because they do not ...
Formulae based on benzalkonium chloride are common in oilfield industry. Microbial corrosion can also apply to plastics, ... They can grow using oxidized sulfur compounds present in the effluent as electron acceptor and excrete hydrogen sulfide (H2S). ...
The compound was first described in 1935 by Ferdinand Münz, who prepared the compound from ethylenediamine and chloroacetic ... It serves as a preservative (usually to enhance the action of another preservative such as benzalkonium chloride or thiomersal ... IDS binds to calcium exceptionally well and forms stable compounds with other heavy metal ions. In addition to having a lower ... Many of the resulting coordination compounds adopt octahedral geometry. Although of little consequence for its applications, ...
Quaternary ammonium compounds. *Benzalkonium. *Benzethonium chloride. *Cetrimonium (bromide/chloride). *Cetylpyridinium. * ... It also reacts with many mercury compounds, giving the corrosive compound mercury iodide, as well as with many metals, making ... kills cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range ...
This organic compound is a white powdered solid with a slight aromatic, phenolic odor. Categorized as a polychloro phenoxy ... Triclosan can react with the free chlorine in chlorinated tap water to produce lesser amounts of other compounds, such as 2,4- ... Because the FDA prohibited hexachlorophene, a compound similar to triclosan, Halden and others argued that the FDA should also ... The compound has been found to bind with low affinity to both the androgen receptor and the estrogen receptor, where both ...
Chemistry of Natural Compounds. 18: 445-7. doi:10.1007/BF00579640. S2CID 4814220. Bailey, D. G.; Dresser, G.; Arnold, J. M. O ... "Identification of benzalkonium chloride in commercial grapefruit seed extracts". J. Agric. Food Chem. 53 (19): 7630-6. doi: ...
The lipid layer consists of fatty compounds that are responsible for decreasing evaporation of the tear film. The mucous layer ... For instance, high concentrations of benzalkonium chloride (BAK) can cause cytotoxicity, cause cell lysis, and reduce tear and ... The aqueous layer consists of a mixture of electrolytes, enzymes, antibodies, antimicrobial proteins, and other compounds. ... Preservatives include benzalkonium chloride (BAK), ethylenediaminetetraacetic acid (EDTA), purite, chlorobutanol, sodium ...
... of benzalkonium chloride (BC), an antimicrobial membrane-active agent commonly used in medical and food-processing environments ... Keywords: Escherichia coli; quaternary ammonium compounds; benzalkonium chloride; selection of subpopulation; efflux pump; ... osmotic and oxidative stress response Escherichia coli; quaternary ammonium compounds; benzalkonium chloride; selection of ... Moen B, Rudi K, Bore E, Langsrud S. Subminimal Inhibitory Concentrations of the Disinfectant Benzalkonium Chloride Select for a ...
Benzalkonium Compounds / administration & dosage * Benzalkonium Compounds / adverse effects * Cell Movement / drug effects ... Phosphate buffered saline (PBS) was used as negative control and 0.02% benzalkonium chloride (BAK) as the toxic control. In ...
Quaternary ammonium compounds (e.g., benzalkonium chloride). *Spray products. Cosmetology. *Acrylic monomers ...
Benzalkonium Compounds * Benzoic Acid / immunology * Camphor / administration & dosage * Camphor / pharmacology * Camphor / ... irritant contact dermatitis to benzalkonium chloride, and in immediate reactions to histamine and benzoic acid (non- ...
Benzalkonium Chloride Compounds on Ultra IBD. LC_GN0536. LC_GN. 0536. Sulfur Antibiotics by UHPLC on Pinnacle DB Biphenyl. LC_ ... Enter a compound, synonym, CAS #, compound class, column name, or keyword below.. Examples:. 1,4-dioxane. 123-91-1, pyrene and ... Our unique library allows you to search for a chromatogram by compound name, synonym, CAS #, compound class, Restek or ... Nicotine-Related Compounds in Urine on Raptor Biphenyl by LC-MS/MS. LC_CF0606. ...
0 (Acetonitriles); 0 (Benzalkonium Compounds); 0 (Quaternary Ammonium Compounds); Z072SB282N (acetonitrile). [Em] M s de ... Quaternary ammonium compounds (QACs) are both cationic surfactants and biocidal substances widely used as disinfectants in the ... The development and validation of a method to simultaneously quantify 12 vitamin D compounds in human serum by LC-MS/MS is ... Detection limits for all compounds were in the picomole range when using a 500 L sample volume. Recovery percentages ranged ...
... amine compounds (amino alcohols, aliphatic polyamines, and the quaternary amine, benzalkonium chloride); tall oil; the ... Cleaning-compounds; Work-environment; Workers; Workplace-monitoring; Occupational-exposure; Exposure-levels; Airway-obstruction ...
1. quaternary ammonium compound [BENZALKONIUM CHLORIDE]. 2. triclosan. - will kill vegetative bacteria, enveloped viruses or ...
... and quaternary ammonium compounds such as benzalkonium chloride, cetyltrimethylammonium bromide and cetylpyridinium chloride. ... For example, the compound or a formulation containing the compound can be administered for at least 2 weeks, preferably about 1 ... Additional compounds can be added to the composition. Exemplary compounds that can be added to the reconstituted formulation ... The term "diluent" refers to chemical compounds that are used to dilute the compound of interest prior to delivery. Diluents ...
Furthermore, it has been discovered that natural occurring compounds alone and in combination with chemical agents can be used ... "Strong" disinfecting agents are compounds such as thimerasol, chlorhexidine, hydrogen peroxide, and benzalkonium chloride. For ... Transcription factor modulating compounds and methods of use thereof. US20050124702 *. 1 Dec 2004. 9 Jun 2005. Alcon, Inc.. Use ... Transcription factor modulating compounds and methods of use thereof. US7419944 *. 29 Nov 2001. 2 Sep 2008. Novartis Ag. ...
These compounds are nitrogenous cationic surface active agents. Benzalkonium chloride is a mixture of alkylbenzyl ... Its active ingredients include quaternary ammonium compounds from the family of benzalkonium chlorides and ...
Benzalkonium chloride (BAK), otherwise known as alkyl dimethyl benzyl ammonium chloride, is a toxic chemical used in cosmetics ... Benzalkonium chloride is a weak allergen but is highly toxic in large amounts and over time (compounding or long-term exposure ... Other names for benzalkonium chloride are: Quaternary ammonium compounds, benzyl-C8-18-alkyldimethyl chlorides; CAS # 63449-41- ... Body systems affected by benzalkonium chloride. In large amounts or from prolonged exposure, benzalkonium chloride may greatly ...
Tobramycin Ophthalmic Solution - ophthalmic, topical (5 ml (dropper)) - Benzalkonium Compounds (Benzalkonium Chloride), ...
A colorless liquid that is used in the manufacture of inorganic and organic nitrates and nitro compounds for fertilizers, dye ... Benzalkonium Compounds (Benzalkonium Chloride) 3. Detergents (Detergent) 4. Nitrogen Dioxide 5. Gases ... Nitric acid (HNO3). A colorless liquid that is used in the manufacture of inorganic and organic nitrates and nitro compounds ...
Compounds need to be hydrophobic enough to get compensation for repulsion effect coming from stationary phase. BTC can be ... Benzalkonium Chloride. Cetylpyridinium Chloride. Sodium. Triton X100. HPLC Separation of Benzalkonium Chloride BCT 8358 on ... Benzalkonium chloride is a mixture of alkylbenzyldimethylammonium chlorides of various even-numbered alkyl chain lengths. It is ... so simultaneous analysis of hydrophobic basic and hydrophilic basic compounds is possible. Condition. Column. Primesep D, 4, ...
Quaternary Ammonium compounds. (e.g. Benzalkonium Chloride). Pyridine Derivatives. (e.g. Cetylpyridinium chloride). ...
Quaternary ammonium compound benzalkonium chloride*Associated with many outbreaks including non-tuberculous Mycobacterium GNR ...
... quarternary ammonium compounds, such as benzalkonium chloride (BZK), benzethonium chloride (BZT), cetylpyridinium chloride (CPC ... It is thus evident that formulating proper dentifrice compositions can be rather complex, both from a compounding standpoint as ... as well as mixtures of these compounds. Typical levels of humectants are from about 20 wt % to about 30 wt % of a toothpaste ... as well as mixtures of these compounds. Typical levels of thickening agents or binders are from about 0 wt % to about 15 wt % ...
... the most common quaternary ammonium compound. Interestingly, the specific benzalkonium chloride uptake (mean uptake per cell) ... the most common quaternary ammonium compound. Interestingly, the specific benzalkonium chloride uptake (mean uptake per cell) ... The study focuses on the disinfection of \textit{Escherichia coli} with benzalkonium chloride, ... The study focuses on the disinfection of Escherichia coli with benzalkonium chloride, ...
Compounds - PhenylAcetic Acid PAA, Acetyl Chloride, Benzaldehyde and Benzoic Acid offered by Krystal Tech, Mumbai, Maharashtra. ... Benzalkonium Chloride 50%. *Molecular formula: C21H38ClN. *CAS No.: 8001-54-5 ... Organic compound. Benzyl Cyanide also known as Phenylacetonitrile. Cas: 140-29-4. Used as a solvent and as a starting material ... Organic Chemicals & Compounds. Offering you a complete choice of products which include PhenylAcetic Acid PAA, Acetyl Chloride ...
BENZALKONIUM CHLORIDE. ICSC. : 1584. Quaternary ammonium compounds, benzyl-C8-18-alkyldimethyl chlorides. ... Benzalkonium chloride itself is a mixture of very similar substances with different chain length and molecular mass.. Other CAS ... The EU classification refers to a group of substances known as quaternary ammonium compounds, benzyl C8-18-alkyldimethyl ...
Disinfectants: benzalkonium chloride, Chlorhexidine and iodinated compounds.. *Other topical ear medications: Bonains Solution ...
Benzalkonium chloride (quaternary ammonium compound) - typically used as a disinfectant in household cleaners for floors and ... The most common culprits that cause irritation include bleach, ammonia and variants of the quaternary ammonia compoundsCredit: ... The most common culprits that cause irritation include bleach, ammonia and variants of the quaternary ammonia compounds, called ...
No 5,385,728 to Suh discloses a dental etching gel containing the quaternary ammonium compound benzalkonium chloride. One ... The phosphoric acid group in these compounds may be replaced with a thiophosphoric acid group. Preferred are 2- ... Visible light curing systems employ light-sensitive compounds such as benzil diketones, and in particular, DL-camphorquinone in ... drawback of quaternary ammonium compounds is that their effectiveness is decreased in the presence of calcium or magnesium ions ...
Quaternary ammonium compounds, diamidines and biguanidines are components of many antiseptic compounds such as benzalkonium ... quaternary ammonium compounds, diamidines and biguanidines [18], which are components of most antiseptic compounds. The ... Novel plasmid-borne gene qacJ mediates resistance to quaternary ammonium compounds in equine Staphylococcus aureus, ...
Within this strain collection, benzalkonium chloride resistance was observed in 12.3% (24/195) of Swiss and 10.6% (21/197) of ... a quaternary ammonium compound widely used in food processing and hospital environments, is a growing public health and food ... Within this strain collection, benzalkonium chloride resistance was observed in 12.3% (24/195) of Swiss and 10.6% (21/197) of ... a quaternary ammonium compound widely used in food processing and hospital environments, is a growing public health and food ...
Benzalkonium chloride is inactivated by organic compounds, including soap, and must not be applied to areas that have not been ... Iodine compounds include tincture of iodine and povidone iodine compounds. Iodine compounds have the broadest spectrum of all ... Iodine compounds include tincture of iodine and povidone iodine compounds. Iodine compounds have the broadest spectrum of all ... Benzalkonium chloride is inactivated by organic compounds, including soap, and must not be applied to areas which have not been ...
... quarternary ammonium compounds, such as benzalkonium chloride (BZK), benzethonium chloride (BZT), cetylpyridinium chloride (CPC ... by weight thereof said wetcake of a dispersant compound selected from the group consisting of at least one borate compound, at ... The term "a borate compound" is intended to encompass any aqueous solution of an inorganic salt including at least one boron ... It has now been realized that the inclusion of a borate compound during precipitated silica wetcake treatment provides an ...
Non-alcoholic sanitisers usually contain Benzalkonium Chloride, a quaternary ammonium compound, as the active ingredient. It is ... Not every compound on the list has been tested against the COVID-19 bug; they are, however, expected to be effective because ... While there are many brands of detergents on the market, soap in its basic capacity, works by breaking up oil-based compounds ... Most alcohol-based sanitisers contain isopropanol, ethanol, n-propanol, or a combination of two of these compounds; at 60% to ...
... benzalkonium is primarily implemented in its salt form, benzalkonium chloride, where it may often be the only active ingredient ... Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with ... Benzalkonium. When used as an active ingredient in products like antibacterial, antiseptic, or disinfectant soaps, topical ... Typically employed as the cetylpyridinium chloride salt, this compound is commonly used as an active ingredient in various over ...
  • For example, the cationic quaternary ammonium compound benzalkonium chloride (BZC) is currently used in several vaginal contraceptive preparations. (asm.org)
  • benzalkonium chloride, Chlorhexidine and iodinated compounds. (fundacionmapfre.org)
  • Hypersensitivity reactions should be considered with organic compounds such as chlorhexidine, benzalkonium and hexachlorophine. (encyclopedia.com)
  • NC/Nga mice were subcutaneously injected with mite allergen (Dp) to induce AD-like skin lesions (ADSLs), and an application of 0.2% (w/v) benzalkonium chloride (BZK), 10% (w/v) povidone-iodine (PVP-I), 80% (v/v) ethanol (Et-OH), or 0.5% (v/v) chlorhexidine gluconate (CHG) was applied to the ear envelope. (medsci.org)
  • Alcohol-free hand sanitisers commonly contain ingredients such as benzalkonium chloride or chlorhexidine digluconate. (which.co.uk)
  • Various studies have revealed that benzalkonium chloride (BKC) has an inhibitory effect on many bacteria but it has no significant effect on Pseudomonas aeruginosa . (scirp.org)
  • They suggest avoiding certain ingredients, like bleach (sodium hypochlorite), quaternary ammonium compounds (benzalkonium chlorides) and glutaraldehyde that can cause asthma. (webwire.com)
  • The cleaning products that induced a positive SIC contained quaternary ammonium compounds (n=10), glutaraldehyde (n=3), both of these agents (n=1) and ethanolamines (n=2). (bmj.com)
  • Let us consider for example alkyldimethylbenzylammonium chloride, commonly known as benzalkonium chloride (BAC). (frontiersin.org)
  • Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. (wikipedia.org)
  • These include some of the chemical compounds used in cleaning products and disinfectants. (webwire.com)
  • Through building assessments, inspections, testing, monitoring and training services, CSC s experts can help prevent needless exposures to cleaning chemicals, disinfectants, other chemical compounds and microbial asthma triggers such as mold. (webwire.com)
  • Quaternary ammonium compounds (QAC) are widely used as disinfectants, biocides, and detergents, among a variety of other applications. (iwaponline.com)
  • and wherein said composition contains less than 1% of any compound selected from the group consisting of an amphoteric surfactant, an anionic surfactant, a halogenated aromatic hydrocarbon, an amide, and a volatile alcohol with a boiling point of under 210.degree. (patents.com)
  • The quatenary ammonium compounds have a surfactant quality which has a detergent like property, disrupting cell membranes, and they are also bacteriostatic or bacteriocidal depending on the concentrations used. (academy.org.uk)
  • Benzalkonium chloride also possesses surfactant properties, dissolving the lipid phase of the tear film and increasing drug penetration, making it a useful excipient, but at the risk of causing damage to the surface of the eye. (wikipedia.org)
  • Furthermore, it has been discovered that natural occurring compounds alone and in combination with chemical agents can be used in ophthalmic solutions such as contact lens solution to enhance and complement their anti-microbial, cleaning and wetting activity or to reduce irritation to the eye. (google.co.uk)
  • Benzalkonium may also find application as a disinfecting agent for instruments, and in low concentration as a preservative for drugs including ophthalmic solutions. (encyclopedia.com)
  • Benzalkonium chloride is a quaternary ammonium compound and is used as a preservative in many ophthalmic solutions. (academy.org.uk)
  • Damage to tear film and corneoconjunctival surface, conjunctivitis (long-term treatment w/ ophth preparations containing benzalkonium Cl as preservative). (mims.com)
  • In the right concentrations, Benzalkonium Chloride is also safe enough to use as a preservative in cosmetics such as eye nasal drops and used in personal lubricants. (qbased.com)
  • benzalkonium chloride 1:5000 is added as preservative. (rxlist.com)
  • Especially for its antimicrobial activity, benzalkonium chloride is an active ingredient in many consumer products: Pharmaceutical products such as eye, ear and nasal drops or sprays, as a preservative. (wikipedia.org)
  • More particularly, the invention relates to compositions and methods for modulating cellular physiology and pathological processing using a combination of compounds that can be found in amniotic membrane preparations. (google.com)
  • The active ingredient in All Stop Healing Gel , Benzalkonium Chloride, is commonly used in pharmaceuticals such as leave-on skin antiseptics, towelettes, wet wipes while also being used in the medical field in preparations used for skin disinfection prior to use of syringes. (qbased.com)
  • Alkyl triethanol ammonium chloride, benzethonium chloride, CETRIMIDE (cetyltrimethylammonium bromide), DYMED and POLYQUAD are also examples of quaternary ammonium compounds that are used in ophthalmic preparations. (academy.org.uk)
  • Systemic toxicity may result from ingestion of iodine-containing compounds or mercury compounds. (encyclopedia.com)
  • A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals. (ewg.org)
  • Benzalkonium chlorides (BACs), also known as alkyl dimethyl benzyl ammonium chlorides, alkyl dimethyl (phenylmethyl) quaternary ammonium chlorides, ammonium alkyl dimethyl (phenylmethyl) chlorides, or ammonium alkyl dimethyl benzyl chlorides, are a class of quaternary ammonium compounds (QACs) ( Fig. 1A ). (asm.org)
  • Quaternary ammonium compounds (QACs), such as benzalkonium chloride (BAC), are broad-spectrum antimicrobials widely used for decades to disinfect environmental surfaces in clinical and industrial settings. (unc.edu)
  • Quaternary ammonium compounds ("quats") like benzalkonium chloride , found in antibacterial spray cleaners and fabric softeners, can cause asthma. (motherearthnews.com)
  • Belongs to the class of quaternary ammonium compound antiseptics. (mims.com)
  • While there are many brands of detergents on the market, soap in its basic capacity, works by breaking up oil-based compounds into small enough particles that can then be washed away with water. (coleparmer.com)
  • Cationic detergents are a group of alkyl- or aryl-substituted quaternary ammonium compounds (eg, benzalkonium chloride, benzathonium chloride, cetylpyridinium chloride) with an ionizable halogen, such as bromide, iodide, or chloride. (merckvetmanual.com)
  • An advantage of benzalkonium chloride, not shared by ethanol-based antiseptics or hydrogen peroxide antiseptic, is that it does not cause a burning sensation when applied to broken skin. (wikipedia.org)
  • Its active ingredients include quaternary ammonium compounds from the family of benzalkonium chlorides and didecyldimethylammonium chloride. (wikipedia.org)
  • Benzalkonium chloride is a mixture of alkylbenzyl dimethylammonium chlorides of various alkyl chain lengths. (wikipedia.org)
  • The EU classification refers to a group of substances known as quaternary ammonium compounds, benzyl C8-18-alkyldimethyl chlorides. (ilo.org)
  • Benzalkonium chlorides (BACs) are chemicals with widespread applications due to their broad-spectrum antimicrobial properties against bacteria, fungi, and viruses. (asm.org)
  • Avoid ingredients that are not safe for asthma, like bleach, ammonia, quaternary ammonium compounds (benzalkonium chlorides), and acetic acid (found in vinegar). (ca.gov)
  • A wide array of Austrian surface waters and wastewater effluents were screened for the selected key compounds, benzalkonium chlorides and dialkyldimethylammonium chlorides with different C-chain lengths. (iwaponline.com)
  • Iodine compounds include tincture of iodine and povidone iodine compounds. (encyclopedia.com)
  • Povidone iodine, an organic compound, is less irritating and less toxic, but not as effective. (encyclopedia.com)
  • Aqueous solutions of iodine have also been used as antiseptic agents, but are less effective than alcoholic solutions and less convenient to use that the povidone iodine compounds. (encyclopedia.com)
  • Before buying bath and cleaning products from your home, make sure that the ingredients list does not contain benzalkonium chloride, or any of its other synonyms (see the introduction). (naturalpedia.com)
  • SAFETY DATA SHEET Product identifier Product code: B1068 Product Name: BENZALKONIUM CHLORIDE, 50 PERCENT SOLUTION, NF Other means of identification Synonyms: No information available CAS #: Mixture RTECS # Not available CI#: Not available Recommended use of the chemical and restrictions on use Recommended use: No information available. (mmmpublicschool.in)
  • Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant. (mims.com)
  • Chemicals of concern include benzalkonium chloride (a quaternary ammonium compound), which is a common disinfectant found in household cleaners used on floors and hard services. (digitaljournal.com)
  • Quaternary ammonium compounds function by disrupting cell membranes of bacteria, subsequently leading to leakage of the cytosol, and degradation of proteins as well as nucleic acids ( McDonnell and Russell, 1999 ). (frontiersin.org)
  • Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. (drugbank.ca)
  • This is a blend of benzalkonium chloride (quaternary ammonium compounds) specially selected for safety of use. (viovet.co.uk)
  • Quaternary ammonium compounds (eg, benzalkonium chloride) are also probably best avoided. (uzh.ch)
  • As a cationic detergent in the family of quaternary ammonium compounds, benzalkonium chloride (BZK) shows strong antiseptic activity against both gram-positive and -negative bacteria. (medsci.org)
  • The polyphenols themselves are unstable, but are chemically converted into more stable substances that belong to a diverse class of products, called quaternary ammonium compounds. (thegojiberry.ca)
  • The activity of older quaternary ammonium compounds is reduced by hard water and by porous or fibrous materials (eg, fabrics, cellulose sponges) that adsorb them. (merckvetmanual.com)
  • However, newer dialkyl quaternary ammonium compounds (fourth generation, including dodecyl dimethyl ammonium bromide, dioctyl dimethyl ammonium bromide, etc) purportedly remain active in hard water and are tolerant of anionic residues. (merckvetmanual.com)
  • Quaternary ammonium compounds are effective against most bacteria, enveloped viruses, some fungi (including yeasts), and protozoa but not against nonenveloped viruses, mycobacteria, and spores. (merckvetmanual.com)
  • The results also suggest that quaternary ammonium compounds are the principal cause of sensitiser-induced occupational asthma among cleaners. (bmj.com)
  • Benzalkonium chloride itself is a mixture of very similar substances with different chain length and molecular mass. (ilo.org)
  • Thimerosol (Mersol) is a mercury compound with activity against bacteria and yeasts. (encyclopedia.com)
  • The benzalkonium chloride is a quaternary ammonium compound, active against bacteria and yeasts. (chemistdirect.co.uk)
  • However, in reference to the FDA rule, the CDC states that it does not have a recommended alternative to ethanol or isopropanol as active ingredients, and adds that "available evidence indicates benzalkonium chloride has less reliable activity against certain bacteria and viruses than either of the alcohols. (wikipedia.org)
  • Exposure of Escherichia coli to a subminimal inhibitory concentration (25% below MIC) of benzalkonium chloride (BC), an antimicrobial membrane-active agent commonly used in medical and food-processing environments, resulted in cell death and changes in cell morphology (filamentation). (mdpi.com)
  • However, as quaternary-ammonium-compound-based hand sanitisers are not commonly used in healthcare, they have yet to gain the same level of credibility as their alcohol-based counterparts. (coleparmer.com)
  • however, topical d-tubocurarine in 0.025% benzalkonium chloride solution or in saponin showed minimal to absent mydriasis in cockatoos (Cacatua species) and pigeons. (thefreelibrary.com)
  • Benzalkonium chloride (Topical). (mims.com)
  • Due to its antimicrobial activity when applied to skin some topical medications for acne vulgaris have benzalkonium chloride added to increase the products' efficiency or shelf-life. (wikipedia.org)
  • Benzalkonium chloride Antiseptic Swab (Tongzhou Ruihong Medical Products Factory). (mims.com)
  • Benzalkonium chloride (alkyl dimethyl benzyl ammonium chloride) is an organic compound that is used as an antiseptic and spermicide. (theaquariumwiki.com)
  • A colorless liquid that is used in the manufacture of inorganic and organic nitrates and nitro compounds for fertilizers, dye intermediates, explosives, and many different organic chemicals. (curehunter.com)
  • MFC has gained attention due to its capability to produce electricity from organic as well as inorganic compounds. (prsync.com)
  • Zinc oxide is an inorganic compound, which is insoluble in water. (prsync.com)
  • Reduced susceptibility of Listeria monocytogenes to benzalkonium chloride (BC), a quaternary ammonium compound widely used in food processing and hospital environments, is a growing public health and food safety concern. (frontiersin.org)
  • The study focuses on the disinfection of Escherichia coli with benzalkonium chloride, the most common quaternary ammonium compound. (frontiersin.org)
  • Benzalkonium chloride (BAK), otherwise known as alkyl dimethyl benzyl ammonium chloride , is a toxic chemical used in cosmetics. (naturalpedia.com)
  • By some estimates, 75 percent of liquid hand soap contains triclosan or other antibacterial compounds. (psmag.com)
  • Because of efflux pumps L. monocytogenes is a multidrug resistant pathogen, not sensitive to many antimicrobial compounds, including tetracycline, amoxicillin, benzalkonium chloride. (vdu.lt)
  • Efflux pumps are membrane transporters which can extrude out of the cells various toxic compounds. (vdu.lt)
  • They are usually commercialized as a mixture of compounds with different lengths for the alkyl chain, ranging from C 8 to C 18 , with higher biocide activity for C 12 and C 14 derivatives ( 1 ). (asm.org)
  • A mixture of alkylbenzyldimethylammonium compounds. (nih.gov)
  • Product name : Benzalkonium Chloride 50% Solution CAS-No. : 63449-41-2 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Industrial & for professional use only. (mmmpublicschool.in)
  • No preservatives (no allergens like Benzalkonium Chloride) or artificial flavors. (therabreath.com)
  • Benzalkonium chloride is inactivated by organic compounds, including soap, and must not be applied to areas that have not been fully rinsed. (encyclopedia.com)
  • Benzalkonium chloride is a mainstay of phase-transfer catalysis, an important technology in the synthesis of organic compounds, including drugs. (wikipedia.org)
  • 10. The composition of claim 9 wherein said benefit agent is selected from the group consisting of a polyhydric alcohol, a polyol, vitamins, skin emollients and anti acne compounds. (patents.com)
  • Instead of alcohol, it contains an ammonium compound called Benzalkonium Chloride (BAC), which parents know little about so they are less concerned, and clinical research shows it destroys 99.9% of germs in 15 seconds including avian flu, SARS, influenza A2 and H1N1 virus. (science20.com)
  • Alcohol-free hand sanitizers regularly substitute the alcohol content with benzalkonium chloride, a quarternary ammonium compound able to reduce microbes albeit not as effectively as does alcohol. (studymalaysia.com)
  • The effects of ichthammol 10% pet, zinc oxide 20% pet, camphor 20% pet, levomenthol 10% pet, tea tree oil 20 or 50% and clobetason butyrate 0.05% ointment were studied in the following experimental models: elicitation of allergic contact dermatitis to nickel, irritant contact dermatitis to benzalkonium chloride, and in immediate reactions to histamine and benzoic acid (non-immunological contact utricaria) respectively. (nih.gov)
  • The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase having the poorly water soluble organic compound. (google.de)
  • Other chemical compounds have varying efficacy, but it's harder to be sure. (which.co.uk)
  • Fifteen L. monocytogenes isolates were tolerant to benzalkonium chloride (BAC), and genes conferring BAC tolerance were found in 13 of them. (asm.org)
  • Phosphate buffered saline (PBS) was used as negative control and 0.02% benzalkonium chloride (BAK) as the toxic control. (nih.gov)
  • Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory, experimental, and clinical studies. (naturalpedia.com)
  • Benzalkonium chloride is a weak allergen but is highly toxic in large amounts and over time (compounding or long-term exposure). (naturalpedia.com)
  • Benzalkonium chloride is considered acutely toxic . (naturalpedia.com)
  • Benzalkonium chloride is highly toxic and may produce many side effects, especially in large quantities and prolonged exposure. (naturalpedia.com)
  • Common agents added include N-halamine compounds, nitric oxide, and copper and silver nanoparticles. (wikipedia.org)
  • 2. The composition of claim 1 wherein said antimicrobial agent is a cationic compound, or a salt or precursor thereof. (patents.com)
  • In large amounts or from prolonged exposure, benzalkonium chloride may greatly affect the respiratory and digestive system. (naturalpedia.com)
  • Benzalkonium chloride Handling and Personal Protection May cause respiratory tract and mucous membrane irritation with sore throat, coughing, shortness of breath, and delayed lung edema. (mmmpublicschool.in)
  • Optimal disinfection protocols are fundamental to minimize bacterial resistance to the compound applied, or cross-resistance to other antimicrobials such as antibiotics. (frontiersin.org)
  • Benzalkonium chloride is also used in many non-consumer processes and products, including as an active ingredient in surgical disinfection. (wikipedia.org)