Analogs or derivatives of mandelic acid (alpha-hydroxybenzeneacetic acid).
Oxidoreductases that are specific for ALDEHYDES.
A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.
A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified according to the acceptor which can be NAD+ or NADP+ (subclass 1.1.1), cytochrome (1.1.2), oxygen (1.1.3), quinone (1.1.5), or another acceptor (1.1.99).
A genus of gram-negative bacteria of the family MORAXELLACEAE, found in soil and water and of uncertain pathogenicity.
A widely used industrial solvent.
A family of isomeric, colorless aromatic hydrocarbon liquids, that contain the general formula C6H4(CH3)2. They are produced by the destructive distillation of coal or by the catalytic reforming of petroleum naphthenic fractions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Organic esters of thioglycolic acid (HS-CH2COOH).
A white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide and used in organic syntheses. This should not be confused with benzoin gum from STYRAX.
Organic compounds containing a carbonyl group in the form -CHO.
A species of gram-negative, aerobic bacteria isolated from soil and water as well as clinical specimens. Occasionally it is an opportunistic pathogen.
A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. Some are common inhabitants of the intestinal tract of vertebrates. These bacteria occasionally cause opportunistic infections in humans.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
A zinc-containing enzyme which oxidizes primary and secondary alcohols or hemiacetals in the presence of NAD. In alcoholic fermentation, it catalyzes the final step of reducing an aldehyde to an alcohol in the presence of NADH and hydrogen.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (From Dorland, 27th ed) (The NADP+ enzyme is EC 1.1.1.42.) EC 1.1.1.41.
A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues.
The rate dynamics in chemical or physical systems.
Enzymes that catalyze the dehydrogenation of GLYCERALDEHYDE 3-PHOSPHATE. Several types of glyceraldehyde-3-phosphate-dehydrogenase exist including phosphorylating and non-phosphorylating varieties and ones that transfer hydrogen to NADP and ones that transfer hydrogen to NAD.
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
An enzyme that catalyzes the conversion of (S)-malate and NAD+ to oxaloacetate and NADH. EC 1.1.1.37.
An aldehyde oxidoreductase expressed predominantly in the LIVER; LUNGS; and KIDNEY. It catalyzes the oxidation of a variety of organic aldehydes and N-heterocyclic compounds to CARBOXYLIC ACIDS, and also oxidizes quinoline and pyridine derivatives. The enzyme utilizes molybdenum cofactor and FAD as cofactors.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.
Enzymes that catalyze a reverse aldol condensation. A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules (ALDEHYDES or KETONES). EC 4.1.2.
The sum of the weight of all the atoms in a molecule.
An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Reversibly catalyze the oxidation of a hydroxyl group of carbohydrates to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2.; and 1.1.99.
A flavoprotein containing oxidoreductase that catalyzes the reduction of lipoamide by NADH to yield dihydrolipoamide and NAD+. The enzyme is a component of several MULTIENZYME COMPLEXES.
Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
An alcohol oxidoreductase which catalyzes the oxidation of L-iditol to L-sorbose in the presence of NAD. It also acts on D-glucitol to form D-fructose. It also acts on other closely related sugar alcohols to form the corresponding sugar. EC 1.1.1.14
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
The functional hereditary units of BACTERIA.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
Enzymes that catalyze the reversible reduction of NAD by NADPH to yield NADP and NADH. This reaction permits the utilization of the reducing properties of NADPH by the respiratory chain and in the reverse direction it allows the reduction of NADP for biosynthetic purposes.
Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.
A glucose dehydrogenase that catalyzes the oxidation of beta-D-glucose to form D-glucono-1,5-lactone, using NAD as well as NADP as a coenzyme.
An enzyme of the oxidoreductase class that catalyzes the reaction 6-phospho-D-gluconate and NADP+ to yield D-ribulose 5-phosphate, carbon dioxide, and NADPH. The reaction is a step in the pentose phosphate pathway of glucose metabolism. (From Dorland, 27th ed) EC 1.1.1.43.
The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Reversibly catalyzes the oxidation of a hydroxyl group of sugar alcohols to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2. and EC 1.1.99.
D-Glucose:1-oxidoreductases. Catalyzes the oxidation of D-glucose to D-glucono-gamma-lactone and reduced acceptor. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.47; EC 1.1.1.118; EC 1.1.1.119 and EC 1.1.99.10.
Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.
Enzymes that catalyze the first step in the beta-oxidation of FATTY ACIDS.
A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. In eukaryotes the enzyme can be found as a component of mitochondrial electron transport complex I. Under experimental conditions the enzyme can use CYTOCHROME C GROUP as the reducing cofactor. The enzyme was formerly listed as EC 1.6.2.1.
A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-.
An enzyme that catalyzes the dehydrogenation of inosine 5'-phosphate to xanthosine 5'-phosphate in the presence of NAD. EC 1.1.1.205.
Alcohol oxidoreductases with substrate specificity for LACTIC ACID.
Flavoproteins that catalyze reversibly the reduction of carbon dioxide to formate. Many compounds can act as acceptors, but the only physiologically active acceptor is NAD. The enzymes are active in the fermentation of sugars and other compounds to carbon dioxide and are the key enzymes in obtaining energy when bacteria are grown on formate as the main carbon source. They have been purified from bovine blood. EC 1.2.1.2.
A flavoprotein oxidoreductase that has specificity for medium-chain fatty acids. It forms a complex with ELECTRON TRANSFERRING FLAVOPROTEINS and conveys reducing equivalents to UBIQUINONE.
An enzyme that catalyzes the oxidation of XANTHINE in the presence of NAD+ to form URIC ACID and NADH. It acts also on a variety of other purines and aldehydes.
Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that is not known to be pathogenic for man, animals, or plants. Its organisms are spoilers for beers and ciders and in sweet English ciders they are the causative agents of a secondary fermentation known as "cider sickness." The species Z. mobilis is used for experiments in molecular genetic studies.
A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
Oxidoreductases that are specific for KETONES.
Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
The E1 component of the multienzyme PYRUVATE DEHYDROGENASE COMPLEX. It is composed of 2 alpha subunits (pyruvate dehydrogenase E1 alpha subunit) and 2 beta subunits (pyruvate dehydrogenase E1 beta subunit).
Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.
A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.
A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Compounds containing the PhCH= radical.
An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.
Sugar alcohol dehydrogenases that have specificity for MANNITOL. Enzymes in this category are generally classified according to their preference for a specific reducing cofactor.
Miniaturized methods of liquid-liquid extraction.
An enzyme that catalyzes the oxidation of UDPglucose to UDPglucuronate in the presence of NAD+. EC 1.1.1.22.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
An enzyme that catalyzes the oxidation and reduction of FERREDOXIN or ADRENODOXIN in the presence of NADP. EC 1.18.1.2 was formerly listed as EC 1.6.7.1 and EC 1.6.99.4.
An NAD-dependent enzyme that catalyzes the reversible DEAMINATION of L-ALANINE to PYRUVATE and AMMONIA. The enzyme is needed for growth when ALANINE is the sole CARBON or NITROGEN source. It may also play a role in CELL WALL synthesis because L-ALANINE is an important constituent of the PEPTIDOGLYCAN layer.
Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.
Isomeric forms and derivatives of pentanol (C5H11OH).
The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)
Catalyzes reversibly the oxidation of hydroxyl groups of prostaglandins.
A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVARY; and the CENTRAL NERVOUS SYSTEM. The enzyme acts reversibly and can use either NAD or NADP as cofactors.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
... coniferyl alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, and aryl-alcohol dehydrogenase (NADP+). Gross GG, Zenk MH ... 2. Purification and properties of aryl-alcohol: NADP-oxidoreductase from Neurospora crassa]". Eur. J. Biochem. (in German). 8 ( ... In enzymology, an aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) is an enzyme that catalyzes the chemical reaction an ... Other names in common use include aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide, phosphate), ...
... coniferyl alcohol dehydrogenase; NADPH-linked benzaldehyde reductase; aryl-alcohol dehydrogenase (NADP), EC 1.1.1.91) adalah ... NADP. +. →. Aldehid aromatik. +. NADPH. +. H. +. {\displaystyle {\mbox{Alkohol aromatik}}+{\mbox{NADP}}^{+}\rightarrow {\mbox{ ... Oksidoreduktase aril-alkohol:NADP+ (bahasa Inggris: aryl-alcohol:NADP+ oxidoreductase, aryl-alcohol dehydrogenase (NADP+), aryl ... Diperoleh dari "https://id.wikipedia.org/w/index.php?title=Aril-alkohol_dehidrogenase_(NADP%2B)&oldid=6804652" ...
... benzaldehyde dehydrogenase (NADP+) MeSH D08.811.682.657.163.515 - betaine-aldehyde dehydrogenase MeSH D08.811.682.657.163.562 ... dihydrouracil dehydrogenase (nad+) MeSH D08.811.682.660.350 - dihydrouracil dehydrogenase (nadp) MeSH D08.811.682.660.385 - ... methylenetetrahydrofolate dehydrogenase (nad+) MeSH D08.811.682.662.253 - methylenetetrahydrofolate dehydrogenase (nadp) MeSH ... malate dehydrogenase MeSH D08.811.682.047.748 - malate dehydrogenase (nadp+) MeSH D08.811.682.047.892 - xanthine dehydrogenase ...
... malate dehydrogenase (NAD(P)+) EC 1.1.1.300: NADP-retinol dehydrogenase EC 1.1.1.301: D-arabitol-phosphate dehydrogenase EC 1.1 ... benzaldehyde dehydrogenase (NAD+) EC 1.2.1.29: aryl-aldehyde dehydrogenase EC 1.2.1.30: aryl-aldehyde dehydrogenase (NADP+) EC ... EC 1.1.1.1: alcohol dehydrogenase EC 1.1.1.2: alcohol dehydrogenase (NADP+) EC 1.1.1.3: homoserine dehydrogenase EC 1.1.1.4: (R ... aldehyde dehydrogenase (NADP+) EC 1.2.1.5: aldehyde dehydrogenase (NAD(P)+) EC 1.2.1.6: deleted EC 1.2.1.7: benzaldehyde ...
... coniferyl alcohol dehydrogenase; NADPH-linked benzaldehyde reductase; aryl-alcohol dehydrogenase (NADP), EC 1.1.1.91) adalah ... NADP. +. →. Aldehid aromatik. +. NADPH. +. H. +. {\displaystyle {\mbox{Alkohol aromatik}}+{\mbox{NADP}}^{+}\rightarrow {\mbox{ ... Oksidoreduktase aril-alkohol:NADP+ (bahasa Inggris: aryl-alcohol:NADP+ oxidoreductase, aryl-alcohol dehydrogenase (NADP+), aryl ... Diperoleh dari "https://id.wikipedia.org/w/index.php?title=Aril-alkohol_dehidrogenase_(NADP%2B)&oldid=6804652" ...
May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation ... Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short ... Aldehyde dehydrogenase X, mitochondrial (ALDH1B1), Aldehyde dehydrogenase, mitochondrial (ALDH2), Aldehyde dehydrogenase family ... May use both NADP+ and NAD+ as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.By ...
Can use both NADP(+) and NAD(+) as electron acceptor (PubMed:17382292). May have a protective role against the cytotoxicity ... Metabolizes also benzaldehyde (PubMed:17382292). Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde (PubMed: ... benzaldehyde dehydrogenase (NAD+) activity Source: UniProtKB-EC. *benzaldehyde dehydrogenase (NADP+) activity Source: UniProtKB ... Aldehyde dehydrogenase family 3 member B1 (ALDH3B1), Aldehyde dehydrogenase, mitochondrial (ALDH2), Aldehyde dehydrogenase ...
3-Hydroxybenzaldehyde , , NADP+ + H2O benzaldehyde , / dehydrogenase ,/ 1.2.1.7 , Search GenBank, 172 hits on Apr. 03, 2012 ... Search Medline for benzaldehyde dehydrogenase. 16 citations on March 09, 2012. ...
Unusual NADPH conformation in the crystal structure of a cinnamyl alcohol dehydrogenase from Helicobacter pylori in complex ... with NADP(H) and substrate docking analysis. Download Prime PubMed App to iPhone, iPad, or Android ... possesses broad substrate specificities like the plant CADs and additionally a dismutation activity converting benzaldehyde to ... Cinnamyl alcohol dehydrogenase is a zinc- and NADPH-dependent dehydrogenase catalyzing the reversible conversion of p- ...
The induction of an aldehyde dehydrogenase isozyme (B-ALDH), which uses aromatic aldehydes such as benzaldehyde as substrate ... and NADP as a cofactor was examined in normal liver and tumors of B6C3F1 male mice. The tumors were induced by either 15 or 45 ... Aldehydes ; Dehydrogenation ; Liver neoplasms ; Markers ; Benzaldehydes ; Nitroso compounds ; Carcinogens ; Phenobarbitol ; ...
... benzaldehyde dehydrogenase (NADP+) MeSH D08.811.682.657.163.515 - betaine-aldehyde dehydrogenase MeSH D08.811.682.657.163.562 ... dihydrouracil dehydrogenase (nad+) MeSH D08.811.682.660.350 - dihydrouracil dehydrogenase (nadp) MeSH D08.811.682.660.385 - ... methylenetetrahydrofolate dehydrogenase (nad+) MeSH D08.811.682.662.253 - methylenetetrahydrofolate dehydrogenase (nadp) MeSH ... malate dehydrogenase MeSH D08.811.682.047.748 - malate dehydrogenase (nadp+) MeSH D08.811.682.047.892 - xanthine dehydrogenase ...
Benzaldehyde dehydrogenase (NADP^+^) Current Synonym true false 2974072014 Benzaldehyde dehydrogenase (nicotinamide adenine ... Benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide phosphate ^+^) (substance). Code System Preferred Concept Name. ...
NADP-linked benzaldehyde dehydrogenase; benzaldehyde dehydrogenase (NADP). Reaction. benzaldehyde + NADP+ + H2O = benzoate + ... Other names in common use include NADP+-linked benzaldehyde dehydrogenase, and benzaldehyde dehydrogenase (NADP+). This enzyme ... The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. ...
Deficiency of benzaldehyde dehydrogenase (NADP^+^) Current Synonym true false 2975192013 Deficiency of benzaldehyde ... Deficiency of benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide phosphate ^+^) (disorder). Code System Preferred ... Deficiency of benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide phosphate ^+^) (disorder). Concept Status. ...
Other name(s): NADP-linked benzaldehyde dehydrogenase; benzaldehyde dehydrogenase (NADP). Systematic name: benzaldehyde:NADP+ ... Other name(s): NADP-acetaldehyde dehydrogenase; NADP-dependent aldehyde dehydrogenase; aldehyde dehydrogenase (NADP). ... Accepted name: benzaldehyde dehydrogenase (NADP+). Reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+. ... Reaction: formate + NADP+ = CO2 + NADPH. Other name(s): NADP-dependent formate dehydrogenase; formate dehydrogenase (NADP). ...
3. Aldehyde dehydrogenase, dimeric NADP-preferring. General function:. Involved in oxidoreductase activity. Specific function: ... Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short ... 8. Aldehyde dehydrogenase family 3 member B2. General function:. Involved in oxidoreductase activity. Specific function:. Not ... 4. Aldehyde dehydrogenase family 1 member A3. General function:. Involved in oxidoreductase activity. Specific function:. ...
NADP(+)) 1.2.1.5 Aldehyde dehydrogenase (NAD(P)(+)) 1.2.1.6 Deleted entry 1.2.1.7 Benzaldehyde dehydrogenase (NADP(+)) 1.2.1.8 ... Benzaldehyde dehydrogenase (NAD(+)) 1.2.1.29 Aryl-aldehyde dehydrogenase 1.2.1.30 Aryl-aldehyde dehydrogenase (NADP(+)) 1.2. ... 2-oxoaldehyde dehydrogenase (NADP(+)) 1.2.1.50 Long-chain-fatty-acyl-CoA reductase 1.2.1.51 Pyruvate dehydrogenase (NADP(+)) ... NADP(+)) 1.2.1.78 2-formylbenzoate dehydrogenase 1.2.1.79 Succinate-semialdehyde dehydrogenase (NADP(+)) 1.2.1.80 Long-chain ...
The VDH substrate specificity followed this order: vanillin (100%) > protocatechualdehyde (91%) > benzaldehyde (79%) > p- ... NL15-2K as a biocatalyst for vanillin production, it is necessary to characterize the vanillin dehydrogenase (VDH) that ... Although peptide mass fingerprinting and BLAST searches indicated that this enzyme is a salicylaldehyde dehydrogenase (SALDH), ... the determined kinetic parameters clearly demonstrated that the enzyme is a vanillin dehydrogenase. Lastly, phylogenetic ...
Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2. ... Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The ... Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega ... Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5 ...
... but shows considerable activity with NADP (in vitro). This protein belongs to the aldehyde dehydrogenases family of proteins. ... Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, ... Knockdown of aldehyde dehydrogenase 8 family, member A1 (ALDH8A1) by siRNA enhances the early stages of HIV-1 replication in ... Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. ...
GO:0018479 [benzaldehyde dehydrogenase (NAD+) activity]. GO:0042493 [response to drug]. GO:0043231 [intracellular membrane- ... GO:0016620 [oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor]. ... GO:0018479 [benzaldehyde dehydrogenase (NAD+) activity]. GO:0043231 [intracellular membrane-bounded organelle]. GO:0044281 [ ... GO:0018479 [benzaldehyde dehydrogenase (NAD+) activity]. GO:0043231 [intracellular membrane-bounded organelle]. GO:0044281 [ ...
... benzaldehyde, and benzyl alcohol, and no affinity for acetophenone (AP) and 2-phenylethanol. CsSDR showed the highest catalytic ... sinensis flowers with a strong preference for NADP/NADPH co-factors, and showed affinity for (R)/(S)-1-phenylethanol (1PE), ... The CsSDR recombinant protein produced in Escherichia coli exhibited dehydrogenase-reductase activity towards several major VPB ... sinensis short-chain dehydrogenase/reductase (CsSDR) was isolated, cloned, sequenced, and functionally characterized. The ...
HNE was used as the substrate instead of benzaldehyde, and 1 mM NAD+ was used as the co-substrate instead of NADP+. ... Figure 3. Effects of RNAi against aldehyde dehydro-genases alh-1 and alh-10. (A) Effect of RNAi against alh-1 and alh-10 on NAD ... 5, 6]). In mammalian cells, several aldehyde dehydrogenases that catalyze the oxidation of the carbonyl group of 4‑HNE are ... aldehyde dehydrogenase), and NAD(P)H-dependent reduction of an aldehyde to an alcohol (aldose reductase). To be able to undergo ...
Aldehyde Dehydrogenase 3 Family Member B1, including: function, proteins, disorders, pathways, orthologs, and expression. ... This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that ... May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation ... Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short ...
Proteomic studies indicated that, among others, a predicted medium-chain dehydrogenase/reductase (MDR) superfamily, zinc- ... dependent alcohol dehydrogenase (locus tag DebiaDRAFT_04514) is specifically and highly produced during growth with acetone. ... for example as a bifunctional 3-hydroxybutanal dehydrogenase/reductase. Its recombinant production may represent an important ... No activity was detectable with NADP+/NADPH, which is also typical of most MDR superfamily dehydrogenase enzymes [28]. ...
NADP^+^),Deficiency of benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide phosphate ^+^),Deficiency of benzaldehyde ... Deficiency of polyol dehydrogenase (NADP^+^),Deficiency of rhamnulokinase,Deficiency of rhamnulokinase (disorder),Deficiency of ... Deficiency of glucose dehydrogenase,Deficiency of glucose dehydrogenase (disorder),Deficiency of glucose oxidase,Deficiency of ... Deficiency of gluconate 2-dehydrogenase,Deficiency of gluconate 2-dehydrogenase (disorder),Deficiency of gluconokinase, ...
Deficiency of benzaldehyde dehydrogenase (NADP^+^),Deficiency of benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide ... Deficiency of polyol dehydrogenase (NADP^+^),Deficiency of rhamnulokinase,Deficiency of rhamnulokinase (disorder),Deficiency of ... Deficiency of benzaldehyde dehydrogenase (nicotinamide adenine dinucleotide phosphate ^+^) (disorder),Deficiency of beta- ... Deficiency of glucose dehydrogenase,Deficiency of glucose dehydrogenase (disorder),Deficiency of glucose oxidase,Deficiency of ...
Subsequently, NADP(H) cofactor preference and enzymatic reducing activity of DHRS7 was determined towards endogenous substrates ... is a previously uncharacterized member of the short-chain dehydrogenase/reductase (SDR) superfamily. While human SDR members ... tree and SDR sequence clusters analysis DHRS7 is a close relative to well-known SDR member 11β-hydroxysteroid dehydrogenase 1 ( ... Dehydrogenase/reductase (SDR family) member 7 (DHRS7, retSDR4, SDR34C1) ...
Larroy C, Parés X, Biosca JA: Characterization of a Saccharomyces cerevisiae NADP(H)-dependent alcohol dehydrogenase (ADHVII), ... The presence of a hydroxyl group on Benzaldehyde or on methoxy-substituted Benzaldehyde resulted in a dramatic drop of the ... rat liver 3-alpha-hydroxysteroid dehydrogenase (3α-HSD) [32] and 3-oxo-5b-steroid 4-dehydrogenase [33], and may be a ... Among the substrates assayed for the oxidation reaction by Pc Aad1p with NADP+ as cofactor, the highest activity was by far ...
D-Phenylserine dehydrogenase and these 6-phosphogluconate dehydrogenases prefer NADP+ to NAD+ as a coenzyme. Moreover, a ... phenylserine from glycine and benzaldehyde as mediated by catalytic bilayer membranes, artificial Vitamin B. 6. -dependent ... 15], and inducible NADP+-dependent D-phenylserine dehydrogenase (Scheme 1) [16]. During the identification of the gene encoding ... NADP. +. -dependent d-threonine dehydrogenase from Pseudomonas cruciviae IFO 12047," Applied and Environmental Microbiology, ...
Isolation and characterization of a benzoylformate decarboxylase and a NAD(+)/NADP(+)-dependent benzaldehyde dehydrogenase ...
... which fits to its classification as short chain dehydrogenase. For in vivo NADPH analyses a codon optimized gene for mBFP was ... which fits to its classification as short chain dehydrogenase. For in vivo NADPH analyses a codon optimized gene for mBFP was ... mBFP catalyzed the NADPH-dependent reduction of benzaldehyde and further aldehydes, ... mBFP catalyzed the NADPH-dependent reduction of benzaldehyde and further aldehydes, ...
NADP L-hexanoate dehydrogenase. NADP Linked Benzaldehyde Dehydrogenase. NADP Malate Dehydrogenase. NADP malate dehydrogenase ... NADP-dependent glyceraldehyde phosphate dehydrogenase activity. NADP-dependent glyceraldehyde-3-phosphate dehydrogenase ... NADP-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase. NADP-dependent retinol dehydrogenase/ ... NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity. ... NADP REDUCTION (U.V.), GLUCOSE-6-PHOSPHATE DEHYDROGENASE. NADP ...
... bypassing pyruvate dehydrogenase [11,13]. The recently characterized snapdragon benzaldehyde dehydrogenase [14] is indeed an ... Catalytic efficiency values for NADP+ are about 2-fold lower (with RF2C more than 3-fold lower) than those for NAD+. Thus, NADP ... 2009) Involvement of snapdragon benzaldehyde dehydrogenase in benzoic acid biosynthesis. Plant J. 59:256-265, doi:10.1111/j. ... This all indicates that in addition to in vivo acetaldehyde, benzaldehyde and coniferaldehyde/sinapaldehyde dehydrogenase ...
  • Other names in common use include aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide, phosphate), coniferyl alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, and aryl-alcohol dehydrogenase (NADP+). (wikipedia.org)
  • Proteomic studies indicated that, among others, a predicted medium-chain dehydrogenase/reductase (MDR) superfamily, zinc-dependent alcohol dehydrogenase (locus tag DebiaDRAFT_04514) is specifically and highly produced during growth with acetone. (biomedcentral.com)
  • The enzyme might play a key role in acetone degradation by D. biacutus , for example as a bifunctional 3-hydroxybutanal dehydrogenase/reductase. (biomedcentral.com)
  • One of the most prominent acetone-inducible proteins observed is encoded by gene (IMG locus tag) DebiaDRAFT_04514, and is annotated as medium-chain dehydrogenase/reductase (MDR) superfamily alcohol dehydrogenase (COG1063 in the Clusters of Orthologous Groups classification system). (biomedcentral.com)
  • To investigate the enzymes involved in the formation of these VPB compounds, a new C. sinensis short-chain dehydrogenase/reductase (CsSDR) was isolated, cloned, sequenced, and functionally characterized. (uni-potsdam.de)
  • The CsSDR recombinant protein produced in Escherichia coli exhibited dehydrogenase-reductase activity towards several major VPB compounds in C. sinensis flowers with a strong preference for NADP/NADPH co-factors, and showed affinity for (R)/(S)-1-phenylethanol (1PE), phenylacetaldehyde, benzaldehyde, and benzyl alcohol, and no affinity for acetophenone (AP) and 2-phenylethanol. (uni-potsdam.de)
  • Biochemical properties of human dehydrogenase/reductase (SDR family) member 7. (ox.ac.uk)
  • Dehydrogenase/reductase (SDR family) member 7 (DHRS7, retSDR4, SDR34C1) is a previously uncharacterized member of the short-chain dehydrogenase/reductase (SDR) superfamily. (ox.ac.uk)
  • Among the candidate genes, the overexpression of the alcohol dehydrogenase gene ADH6 , acetaldehyde dehydrogenase gene ALD6 , glucose-6-phosphate 1-dehydrogenase gene ZWF1 , NADH-dependent aldehyde reductase gene YNL134C , and aldo-keto reductase gene YJR096W increased 177, 25, 6, 15, and 18 % of the strain μ max in the medium containing 1 g L −1 vanillin. (biomedcentral.com)
  • These findings have suggested that this enzyme also acts as prostaglandin oxidoreductase, carbonyl reductase, dihydrodiol dehydrogenase and bile acid-binding protein in the tissue. (aspetjournals.org)
  • No benzyl alcohol or benzaldehyde reductase (BAR) activity was detected in the non-fragrant variety "Fenghou. (frontiersin.org)
  • Structure analysis revealed that R. glutinosa iridoid synthases contain six conserved short-chain dehydrogenase/reductase( SDR) motifs,and their 3 D models were composed typical dinucleotide-binding " Rossmann" folds covered by helical C-terminal extensions. (bvsalud.org)
  • mBFP catalyzed the NADPH-dependent reduction of benzaldehyde and further aldehydes, which fits to its classification as short chain dehydrogenase. (frontiersin.org)
  • In enzymology, an aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) is an enzyme that catalyzes the chemical reaction an aromatic alcohol + NADP+ ⇌ {\displaystyle \rightleftharpoons } an aromatic aldehyde + NADPH + H+ Thus, the two substrates of this enzyme are aromatic alcohol and NADP+, whereas its 3 products are aromatic aldehyde, NADPH, and H+. (wikipedia.org)
  • Cinnamyl alcohol dehydrogenase is a zinc- and NADPH-dependent dehydrogenase catalyzing the reversible conversion of p-hydroxycinnamaldehydes to their corresponding hydroxycinnamyl alcohols. (unboundmedicine.com)
  • The purified recombinant protein required zinc as cofactor, and accepted NADH/NAD + but not NADPH/NADP + as electron donor/acceptor. (biomedcentral.com)
  • Molecular cloning and characterization of vanillin dehydrogenase from Streptomyces sp. (biomedcentral.com)
  • We report here the cloning of an aryl-alcohol dehydrogenase cDNA from the white-rot fungus Phanerochaete chrysosporium , its expression in Escherichia coli and the biochemical characterization of the encoded GST and His 6 tagged protein. (beds.ac.uk)
  • We report here the molecular cloning and characterization of the corresponding cDNA, CAD 1-5, which encodes this novel aromatic alcohol dehydrogenase. (deepdyve.com)
  • The induction of an aldehyde dehydrogenase isozyme (B-ALDH), which uses aromatic aldehydes such as benzaldehyde as substrate and NADP as a cofactor was examined in normal liver and tumors of B6C3F1 male mice. (epa.gov)
  • Aldehyde dehydrogenases are a group of NAD(P)+ -dependent enzymes that catalyze the oxidation of aldehydes, such as those derived from catecholamines, to their corresponding carboxylic acids. (hmdb.ca)
  • Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. (genecards.org)
  • The efficient lignin oxidation system of this fungus requires cyclic redox reactions involving the reduction of aryl-aldehydes to the corresponding alcohols by aryl-alcohol dehydrogenase. (beds.ac.uk)
  • The purified recombinant enzyme was found to be active in the reduction of more than 20 different aryl- and linear aldehydes showing highest specificity for mono- and dimethoxylated Benzaldehyde at positions 3, 4, 3,4 and 3,5. (beds.ac.uk)
  • Aldehyde dehydrogenases (ALDHs) are responsible for oxidation of biogenic aldehyde intermediates as well as for cell detoxification of aldehydes generated during lipid peroxidation. (biochemj.org)
  • Aldehyde dehydrogenases (ALDHs) constitute a superfamily of NAD(P) + -dependent enzymes that catalyse irreversible oxidation of aldehydes to the corresponding carboxylic acids. (biochemj.org)
  • By careful selection of appropriate enzymes (alcohol dehydrogenases [ADH] and cofactor recycling enzymes), cofactor recycling of NADH can be performed in the presence of NADP + recycling to achieve overall ( R )- or ( S )-selective deracemisations of sec -alcohols or stereoinversion representing a possible concept for a "green" equivalent to the chemical-intensive Mitsunobu inversion. (organic-chemistry.org)
  • The genes encoding the four alcohol dehydrogenases (ADHs) were cloned from strain GX-UN120. (biomedcentral.com)
  • Members use NADP as a cofactor. (umbc.edu)
  • Subsequently, NADP(H) cofactor preference and enzymatic reducing activity of DHRS7 was determined towards endogenous substrates with a steroid structure (cortisone, 4-androstene-3,17-dion) and also toward relevant exogenous substances bearing a carbonyl group harmful to human health (1,2-naphtoquinone, 9,10-phenantrenequinone). (ox.ac.uk)
  • This family of dehydrogenases act on aldehyde substrates. (umbc.edu)
  • L -Phenylserine and L - threo -(2-thienyl)serine were good substrates for L -phenylserine dehydrogenase. (hindawi.com)
  • Moreover, recombinant CAD 1 can also utilize a wide range of aromatic substrates including unsubstituted and substituted benzaldehydes. (deepdyve.com)
  • A CAD homolog from Helicobacter pylori (HpCAD) possesses broad substrate specificities like the plant CADs and additionally a dismutation activity converting benzaldehyde to benzyl alcohol and benzoic acid. (unboundmedicine.com)
  • The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. (creative-enzymes.com)
  • GO annotations related to this gene include oxidoreductase activity and 3-chloroallyl aldehyde dehydrogenase activity . (genecards.org)
  • NL15-2K as a biocatalyst for vanillin production, it is necessary to characterize the vanillin dehydrogenase (VDH) that degrades the produced vanillin to vanillic acid, as well as the gene encoding this enzyme. (biomedcentral.com)
  • Although peptide mass fingerprinting and BLAST searches indicated that this enzyme is a salicylaldehyde dehydrogenase (SALDH), the determined kinetic parameters clearly demonstrated that the enzyme is a vanillin dehydrogenase. (biomedcentral.com)
  • The purified ORF3 enzyme showed L -phenylserine dehydrogenase activity. (hindawi.com)
  • The enzyme was also capable of oxidizing aryl-alcohols with NADP + at 30°C and an optimum pH of 10.3 but with 15 to 100-fold lower catalytic efficiency than for the reduction reaction. (beds.ac.uk)
  • D-malic acid complexes with malic dehydrogenase and NADH, but is enzymatically inactive. (drclark.net)
  • 13. The method of claim 1, wherein the recombinant host cell further expresses at least one protein selected from the group consisting of citrate synthase with reduced sensitivity to NADH and pyruvate dehydrogenase with reduced sensitivity to NADH. (patentsencyclopedia.com)
  • 19. The method of claim 15, wherein the pyruvate dehydrogenase with reduced sensitivity to NADH is a pyruvate dehydrogenase comprising an E354K amino acid mutation. (patentsencyclopedia.com)
  • This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity. (umbc.edu)
  • Different genetic constructs were created and tested in order to obtain balanced expression levels of the dehydrogenase enzymes in E. coli . (hims-biocat.eu)
  • 8. The method of claim 1, wherein the recombinant host cell further has a deficiency in activity of one or more enzymes selected from the group consisting of pyruvate oxidase (poxB), pyruvate-formate lyase (pflB), phosphotransacetylase (pta), acetate kinase (ackA), aldehyde dehydrogenase (aldB), alcohol dehydrogenase (adhE), alcohol dehydrogenase (adhP), methylglyoxal synthase (mgsA), and lactate dehydrogenase (ldhA). (patentsencyclopedia.com)
  • To enhance recombinant protein production by CHO cells, We compared the impact of overexpression of metabolic enzymes, namely pyruvate carboxylase 2 (PYC2), malate dehydrogenase â ¡ (MDH2), alanine aminotransferase â (ALT1), ornithine transcarbamylase (OTC), carbamoyl phosphate synthetase â (CPSâ ), and metabolism related proteins, namely taurine transporter (TAUT) and Vitreoscilla hemoglobin (VHb), on transient expression of anti-hLAG3 by ExpiCHO-S. Overexpression of these 7 proteins could differentially enhance antibody production. (bvsalud.org)
  • Mass spectrometric analysis of semi-purified fraction revealed that carp liver lactate dehydrogenase (LDH) contained bound lactate which was converted to pyruvate in the presence of NAD. (bvsalud.org)
  • glutathione-dependent formaldehyde dehydrogenase. (qmul.ac.uk)
  • Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. (nih.gov)
  • cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12. (nih.gov)
  • This gene encodes a member of the aldehyde dehydrogenase protein family. (genecards.org)
  • ALDH3B1 (Aldehyde Dehydrogenase 3 Family Member B1) is a Protein Coding gene. (genecards.org)
  • This protein belongs to the aldehyde dehydrogenases family of proteins. (nih.gov)
  • To date, 19 aldehyde dehydrogenase genes have been identified in the human genome. (hmdb.ca)
  • The genes encoding L -phenylserine dehydrogenase and D -phenylserine dehydrogenase, which is induced by phenylserine, are located in a single operon. (hindawi.com)
  • In this paper, we report the identification and cloning of the genes encoding D -phenylserine dehydrogenase and L -phenylserine dehydrogenase. (hindawi.com)
  • Mutagenesis studies have shown that these genes are not essential for growth on tetralin or fatty acids, although a thnG disruption mutant showed threefold less pimelic semialdehyde dehydrogenase activity. (pubmedcentralcanada.ca)
  • In this work, we have characterized the biochemical properties of an aryl-alcohol dehydrogenase from the white-rot fungus Phanerochaete chrysosporium . (beds.ac.uk)
  • The gene products are similar to nonacylating aldehyde dehydrogenases (ThnG) and to proteins representing a complete β-oxidation pathway (ThnH to ThnP). (pubmedcentralcanada.ca)
  • Glutaryl-CoA dehydrogenase (ThnN) would catalyze the oxidation and decarboxylation of glutaryl-CoA and yield crotonyl-CoA, which enters the central metabolism via acetyl-CoA. (pubmedcentralcanada.ca)
  • This reaction could take place by two different methods: via an acylating aldehyde dehydrogenase (ALDH) that could catalyze the reaction to yield pimeloyl-CoA in one step or via the oxidation of pimelic semialdehyde to pimelic acid by a nonacylating ALDH, including its subsequent activation by a CoA-ligase or a CoA-transferase. (pubmedcentralcanada.ca)
  • Moreover, the enzymological properties of L -phenylserine dehydrogenase (Scheme 1 ) overexpressed in Escherichia coli are described. (hindawi.com)
  • Hyperprolinemia, also known as proline oxidase deficiency , is related to hyperprolinemia, type i and hyperprolinemia, type ii , and has symptoms including seizures An important gene associated with Hyperprolinemia is PRODH (Proline Dehydrogenase 1), and among its related pathways/superpathways are Arginine and proline metabolism and Metabolism . (malacards.org)
  • L -Phenylserine dehydrogenase reaction. (hindawi.com)
  • Reaction of benzaldehydes with a DCO 2 D-triethylamine mixture and the same Ru catalyst affords the S deuterated alcohols in high ee. (organic-chemistry.org)
  • Together with EC 1.12.1.2 hydrogen dehydrogenase, forms a system previously known as formate hydrogenlyase. (qmul.ac.uk)
  • 2. Quayle, J.R. Formate dehydrogenase. (qmul.ac.uk)
  • 3. Jollie, D.R. and Lipscomb, J.D. Formate dehydrogenase from Methylosinus trichosporium OB3b. (qmul.ac.uk)
  • Has highest activity with benzaldehyde and decanal (in vitro). (nih.gov)
  • Has a preference for NAD, but shows considerable activity with NADP (in vitro). (nih.gov)
  • The NADP + -dependent dehydrogenase activity of a predominant isoenzyme of human liver 3α-hydroxysteroid dehydrogenase was activated by antihyperlipidemic drugs, such as bezafibrate and clinofibrate, and by clofibric acid and fenofibric acid (active metabolites of clofibrate and fenofibrate, respectively). (aspetjournals.org)
  • ThnG has a nonacylating NAD-dependent pimelic semialdehyde dehydrogenase activity that renders pimelic acid a seven-carbon dicarboxylic acid. (pubmedcentralcanada.ca)
  • Succinic semialdehyde dehydrogenase (SSADH) from the acidogenic fungus Aspergillus niger was purified from GABA grown mycelia to the highest specific activity of 277 nmol min-1 mg-1, using phenyl Sepharose and DEAE Sephacel chromatography. (bvsalud.org)
  • Further, the inactivation of vdh , which encodes vanillin dehydrogenase (VDH), has been demonstrated in Amycolatopsis sp. (biomedcentral.com)
  • Maleic acid is competitive inhibitor of succinic dehydrogenase. (drclark.net)
  • The gene encoding D -phenylserine dehydrogenase from Pseudomonas syringae NK-15 was identified, and a 9,246-bp nucleotide sequence containing the gene was sequenced. (hindawi.com)
  • Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. (umbc.edu)
  • Based on phylogenetic tree and SDR sequence clusters analysis DHRS7 is a close relative to well-known SDR member 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) that participates in metabolism of endogenous and xenobiotic substances with carbonyl group. (ox.ac.uk)
  • We previously developed a hydrogen-borrowing amination by combining an alcohol dehydrogenase (ADH) with an amine dehydrogenase (AmDH) in vitro . (hims-biocat.eu)
  • A fall in malate concentration due to malonate causes depletion of NADP. (drclark.net)
  • The transcriptome analysis suggested the reductases and dehydrogenases of this vanillin resistant strain were up-regulated. (biomedcentral.com)
  • The roles of these reductases and dehydrogenases in the vanillin tolerance and detoxification abilities of S. cerevisiae are described. (biomedcentral.com)
  • Aldehyde Dehydrogenase as a Marker for Chemically Initiated Mouse Liver Tumors. (epa.gov)
  • NAD + , NADP + , yeast extract, and molecular-weight marker-proteins for gel filtration were from Oriental Yeast (Tokyo, Japan). (hindawi.com)
  • Yeast alcohol dehydrogenase (ADH) catalyzes the final metabolic step in ethanol fermentation, and thus plays an important role. (biomedcentral.com)
  • Aldehyde dehydrogenase family. (umbc.edu)
  • The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. (umbc.edu)
  • A combination of a chiral Ru complex and KO t Bu catalyzes an asymmetric transfer hydrogenation of various benzaldehyde-1-d derivatives with 2-propanol to yield ( R )-benzyl-1-d alcohols in high ee and with high isotopic purity. (organic-chemistry.org)
  • 3. The method of claim 1, wherein the recombinant host cell underexpresses alpha-ketoglutarate dehydrogenase. (patentsencyclopedia.com)
  • 4. The method of claim 1, wherein the recombinant host cell does not express alpha-ketoglutarate dehydrogenase. (patentsencyclopedia.com)