Belladonna Alkaloids
Atropa belladonna
Solanaceous Alkaloids
Atropa
Alkaloids
Materia Medica
Materials or substances used in the composition of traditional medical remedies. The use of this term in MeSH was formerly restricted to historical articles or those concerned with traditional medicine, but it can also refer to homeopathic remedies. Nosodes are specific types of homeopathic remedies prepared from causal agents or disease products.
Delphinium
Scopolamine Hydrobromide
An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
Ergot Alkaloids
Pyrrolizidine Alkaloids
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
Vinca Alkaloids
Atropine
Randomized double-blind placebo-controlled trial of homoeopathic 'proving' for Belladonna C30. (1/5)
Homoeopathic drug pictures are developed by recording the symptomatic effects of homoeopathic remedies given to healthy volunteers (a 'proving'). In a double-blind randomized controlled trial we tested the hypothesis that individuals using an infinitesimal dilution of Belladonna (thirtieth potency, C30) would record more true symptoms, on a questionnaire that contained both true and false Belladonna proving symptoms, than those receiving placebo. 60 volunteers entered the study and 47 completed data collection. We were unable to distinguish between Belladonna C30 and placebo using our primary outcome measure. For the secondary outcome measure we analysed the number of individuals who proved to the remedy according to our predefined criteria: 4 out of 19 proved in the Belladonna C30 group and 1 out of 27 in the placebo group (difference not statistically significant). This pilot study does not demonstrate a clear proving reaction for Belladonna C30 versus placebo, but indicates how the question might be further investigated. (+info)Belladonna alkaloids-induced behavioral changes and amnesia on open-field and step-through in 18-, 28-, and 38-day-old mice. (2/5)
AIM: To study the age-related changes of atropine (Atr), scopolamine (Sco), anisodine (AT3), and anisodamine (Ani) on behaviors and memories. METHODS: The behaviors and memories were measured with open-field test and step-through task. M-cholinergic receptors were determined by [3H] quinuclidinyl benzilate ([3H] QNB). RESULTS: During acquisition session (d 1) the 18-, 28-, and 38-d-old mice pretreated with Atr, Sco, and AT3 (0.02, 0.2, 2, or 20 mg.kg-1, i.p.) in open-field test showed increase in walking counts by 26%-42%, but decrease in rearing, grooming, and defecating counts for 50%-92%, 67%-100%, and 75%-100%, respectively. On recall session (d 2) the walking and rearing behaviors in the 18- and 28-d-old mice receiving Atr, Sco, and AT3 on d 1 were higher than those in the mice receiving saline. But a lower grooming behavior on d 2 was found in the mice receiving the drugs on d 1. On d 1 Ani 20 mg.kg-1 reduced the rearing behavior by 50% in 18-d-old mice and defecation by 33%-36% in 18- and 28-d-old mice. All the 4 belladonna alkaloids increased the number of avoidance-response errors and decreased the retention latencies in step-through task. Bmax of [3H] QNB binding sites in frontal cortex and hippocampus regions in the 38-d-old mice increased 7% and 23% vs in the mice of 18 d of age, respectively. CONCLUSION: 1) The effects of the belladonna alkaloids on behaviors and memories in adult mice were weaker than those in young mice. 2) The belladonna alkaloids-induced amnesia on passive avoidance-response in step-through was more sensitive than behavioral changes and amnesia on open-field. 3) According to the lowest effective doses which insulted the behaviors or memories in young mice, Sco was about 10, 100, and 1000 times more potent than Atr, AT3, and Ani, respectively. (+info)Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase. (3/5)
Putrescine N-methyltransferase (PMT) is the first alkaloid-specific enzyme for nicotine and tropane alkaloid formation. The pmt gene from Nicotiana tabacum was fused to the CaMV 35S promoter and integrated into the Atropa belladonna genome. Transgenic plants and derived root cultures were analysed for gene expression and for levels of alkaloids and their precursors. Scopolamine, hyoscyamine, tropine, pseudotropine, tropinone, and calystegines were found unaltered or somewhat decreased in pmt-overexpressing lines compared to controls. When root cultures were treated with 5% sucrose, calystegine levels were elevated in control roots, but were not affected in pmt-overexpressing roots. 1 microM auxin reduced calystegine levels in control roots, while in pmt-overexpressing roots all alkaloids remained unaltered. Expression level of pmt alone is apparently not limiting for tropane alkaloid formation in A. belladonna. (+info)Nitrous oxide and oral premedication. (4/5)
Patients frequently require conscious-sedation to achieve anxiety relief in the dental office. There are specific indications, contraindications, advantages, and disadvantages to each sedation modality. Selection of the appropriate anesthetic technique should be individualized for each patient. This paper reviews two important conscious-sedation modalities: oral premedication and nitrous oxide/oxygen inhalation sedation.Pertinent drugs are reviewed and recommendations are made for their use; current researches are presented and new areas for investigation are suggested. (+info)Anticholinergic poisoning associated with an herbal tea--New York City, 1994. (5/5)
Inadvertent anticholinergic poisoning can result from consumption of foods contaminated with plants that contain belladonna alkaloids. During March 1994, the New York City Department of Health (NYCDOH) investigated seven cases of anticholinergic poisoning in members of three families; three of the seven ill persons required emergency treatment for characteristic manifestations. For all cases, manifestations occurred within 2 hours after drinking tea made from leaves purchased commercially and labeled as Paraguay tea--an herbal tea derived from the plant llex paraguariensis, which is native to South America. This report summarizes the investigation of these cases. (+info)
Datura stramonium
ISBN 0-07-056089-7. Glatstein, Miguel; Alabdulrazzaq, Fatoumah; Scolnik, Dennis (2016). "Belladonna Alkaloid Intoxication". ... It contains tropane alkaloids which are responsible for the psychoactive effects, and may be severely toxic. Datura stramonium ... Adding nitrogen fertilizer to the soil increases the concentration of alkaloids present in the plant. D. stramonium can be ... All parts of Datura plants contain dangerous levels of the tropane alkaloids atropine, hyoscyamine, and scopolamine, which are ...
Donnatal
Several office-belladonna alkaloids ed case series also presented positive outcomes for almost 1,000 patients on the effect of ... Only the phenobarbital group demonstrated a significant change in pain type compared to belladonna alkaloids at the end of the ... A small assessment of sustained release of 0.4 mg belladonna alkaloids and ~60 mg phenobarbital (1 grain) was performed in ... Patients on Donnatal® tablets, belladonna alkaloids, and placebo all had non-significant (p > 0.149) shifts to dull pain, 39.5 ...
Amaryllis belladonna
Several compounds have been found in A. belladonna bulbs, including, 1,4-dihydroxy-3-methoxy powellan, which is an alkaloid. It ... Amaryllis belladonna, the Jersey lily, belladonna-lily, naked-lady-lily, or March lily, is a plant species native to Cape ... Amaryllis belladonna is found in South Africa, where the plants are found growing among rocks. Leaves of A. belladonna begin ... The specific epithet belladonna is derived from the Italian bella donna, which means beautiful lady. There are many common ...
Cholinergic blocking drugs
Naturally occurring antimuscarinics were found in alkaloids from Belladonna (Solanaceae) plants. They were used as deadly ... Naturally occurring antimuscarinics were found in alkaloids from Belladonna (Solanaceae) plants. They were used as deadly ... The name Belladonna, meaning beautiful ladies, was derived from women using berry juice from the plant cosmetically to dilate ...
Medicinal plants
Deadly nightshade, Atropa belladonna, yields tropane alkaloids including atropine, scopolamine and hyoscyamine. Anthraquinone ... The opium poppy Papaver somniferum is the source of the alkaloids morphine and codeine. The alkaloid nicotine from tobacco ... "Chemical and Biological Aspects of Narcissus Alkaloids". In Cordell, G. A. (ed.). The Alkaloids: Chemistry and Biology. Vol. 63 ... The alkaloids are bitter-tasting and toxic, and concentrated in the parts of the plant such as the stem most likely to be eaten ...
Butabarbital
... is also sold in combination with belladonna alkaloids under the brand name Butibel. The belladonna is added for ... This product contains a low dose of butabarbital combined with a standardised mix of belladonna alkaloids and is used as an ... Another similar product is Donnatal, which contains belladonna alkaloids combined with phenobarbital. Barbiturates were first ...
Phytochemistry
Deadly nightshade, Atropa belladonna, yields tropane alkaloids including atropine, scopolamine and hyoscyamine. N,N- ... The opium poppy Papaver somniferum is the source of the alkaloids morphine and codeine. The alkaloid nicotine from tobacco ... Alkaloids are bitter-tasting chemicals, widespread in nature, and often toxic. There are several classes with different modes ... "Atropa Belladonna" (PDF). The European Agency for the Evaluation of Medicinal Products. 1998. Retrieved 26 February 2017. ...
Amaryllis
"Alkaloid constituents of the Amaryllidaceae plant Amaryllis belladonna L." Molecules. 22 (9): 1437. doi:10.3390/ ... 606-607 "Amaryllis belladonna (March lily, Belladonna)". Biodiversity Explorer. Archived from the original on 2018-01-25. ... belladonna has gained the Royal Horticultural Society's Award of Garden Merit. Amaryllis belladonna has been crossed in ... Amaryllis belladonna was introduced into cultivation at the beginning of the eighteenth century. It reproduces slowly by either ...
Cycloplegia
Belladonna alkaloids are used for testing the error of refraction and examination of eye. Cycloplegic drugs are generally ...
Secondary metabolite
Atropine is an alkaloid first found in Atropa belladonna, a member of the nightshade family. While atropine was first isolated ... and taxol Heterocyclic or typical alkaloids, for example quinine, caffeine, and nicotine Examples of alkaloids produced by ... Codeine, also an alkaloid derived from the opium poppy, is considered the most widely used drug in the world according to World ... Alkaloids are a diverse group of nitrogen-containing basic compounds. They are typically derived from plant sources and contain ...
Atropa belladonna
The tropane alkaloids of A. belladonna were used as poisons, and early humans made poisonous arrows from the plant. In Ancient ... Belladonna nectar is transformed by bees into honey that also contains tropane alkaloids. The berries pose the greatest danger ... In the United States, there is only one approved prescription drug containing belladonna alkaloids such as atropine, and the ... The common name belladonna originates from its historic use by women, as bella donna is Italian for "beautiful woman". Drops ...
Phytochemical
The tropane alkaloids of Atropa belladonna were used as poisons, and early humans made poisonous arrows from the plant. In ... Michael (1998). Alkaloids : biochemistry, ecology, and medicinal applications. New York: Plenum Press. p. 20. ISBN 978-0-306- ... Webb, L. J. (Leonard James) (1950), An Australian phytochemical survey : Alkaloids in Queensland flowering plants, Brisbane, ...
B&O Supprettes
... is the brand name for a prescription medication containing powdered opium and belladonna alkaloids in a ... of belladonna and 30 mg (1/2 grain) of opium. Each B&O Supprettes suppository #16 A contains 16.2 mg of belladonna and 60 mg (1 ... "Baltimore Washington Medical Centre Medical Library: Belladonna and Opium". Archived from the original on February 22, 2014. ... belladonna/opium suppository') is an "unapproved" drug according to the Food and Drug Administration (FDA) - that is, the drug ...
Muscarinic antagonist
... are belladonna alkaloids, and are naturally extracted from plants such as Atropa belladonna, the deadly nightshade. The name " ... "belladonna", Italian for "beautiful lady", is thought to derive from one of the antimuscarinic effects of these alkaloids: they ... "Belladonna: MedlinePlus Supplements". medlineplus.gov. Retrieved 2020-08-13. Ritter, James (2020). Rang and Dale's pharmacology ...
Flying ointment
Twilight sleep was a mixture of scopolamine, a belladonna alkaloid, and morphine, a Papaver alkaloid, that was injected and ... For instance, King's American Dispensatory states in the entry on belladonna: "Belladonna and opium appear to exert ... The synergy between belladonna and poppy alkaloids was made use of in the so-called "twilight sleep" that was provided for ... Belladonna or deadly nightshade, Atropa belladonna (virulent poison) Henbane flower Jimsonweed flower Jimsonweed seed capsule ...
List of MeSH codes (D03)
... belladonna alkaloids MeSH D03.132.889.180.297 - atropine MeSH D03.132.889.180.297.297 - atropine derivatives MeSH D03.132. ... belladonna alkaloids MeSH D03.132.760.180.297 - atropine MeSH D03.132.760.180.848 - scopolamine MeSH D03.132.760.200 - ... indole alkaloids MeSH D03.438.473.402.255 - curare MeSH D03.438.473.402.255.712 - toxiferine MeSH D03.438.473.402.255.712.050 ... salsoline alkaloids MeSH D03.438.612.500 - nalidixic acid MeSH D03.438.733.315 - flavins MeSH D03.438.733.315.650 - riboflavin ...
Butalbital
... belladonna alkaloids (trade name: Cafergot-PB) There are specific treatments which are appropriate for targeting migraines and ...
ATC code A06
A06AB09 Bisoxatin A06AB20 Contact laxatives in combination A06AB30 Contact laxatives in combination with belladonna alkaloids ...
ATC code A03
A03BA01 Atropine A03BA03 Hyoscyamine A03BA04 Belladonna total alkaloids A03BB01 Butylscopolamine A03BB02 Methylatropine A03BB03 ... A03CA34 Propantheline and psycholeptics A03CB01 Methylscopolamine and psycholeptics A03CB02 Belladonna total alkaloids and ...
Littorine
... is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in ... Tropane alkaloids, Tropane alkaloids found in Solanaceae, Carboxylate esters). ... Catuabine Scopine Evans, W. C.; Ghani, A.; Woolley, V. A. (1972). "Distribution of littorine and other alkaloids in the roots ... "Isolation and identification of littorine from hairy roots of Atropa belladonna". Plant Cell Reports. 18 (3-4): 249-251. doi: ...
Management of Parkinson's disease
The positive albeit modest effects of anticholinergic alkaloids obtained from the plant of the belladonna were described during ...
Alkaloid
For example, atropine is isolated from the plant Atropa belladonna; strychnine is obtained from the seed of the Strychnine tree ... of those contain alkaloids. Therefore, in the past the term "alkaloid" was associated with plants. The alkaloids content in ... attributed to isoquinoline alkaloids. Main classes of monomeric alkaloids are listed in the table below: Most alkaloids contain ... Most alkaloids are present in the raw plants in the form of salts of organic acids. The extracted alkaloids may remain salts or ...
History of Parkinson's disease
The positive albeit modest effects on tremor of anticholinergic alkaloids obtained from the plant of the belladonna were ...
Corydalis flavula
... medicine gleaned some of the aboriginal understandings of the power of plant alkaloids like heroin for pain and belladonna for ... an order of plants that often contains many alkaloids that make plants distasteful to toxic. Early use by Native Americans ...
Gümüşhane
... a plant rich in medicinally valuable tropane alkaloids of the type found also in belladonna. The cave in Gümüşhane most visited ...
Solanaceae
... and sources of psychoactive alkaloids, Datura, Mandragora (mandrake), and Atropa belladonna (deadly nightshade). Certain ... To humans, these alkaloids can be desirable, toxic, or both. The tropanes are the most well-known of the alkaloids found in the ... They are found in plants such as henbane (Hyoscyamus albus), belladonna (Atropa belladonna), jimson weed (Datura stramonium), ... belladonna (Atropa belladonna), jimson weed or devil's snare (Datura stramonium) and Brugmansia , as well as many others in the ...
Tropane alkaloid
Anticholinergic drugs and deliriants: Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna) Hyoscyamine ... Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their ... Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and ... They are not considered to be alkaloids per definition. The biosynthesis of the tropane alkaloids have attracted intense ...
Pyridine
... is not abundant in nature, except for the leaves and roots of belladonna (Atropa belladonna) and in marshmallow ( ... Althaea officinalis). Pyridine derivatives, however, are often part of biomolecules such as alkaloids. In daily life, trace ...
Nicandra physalodes
... including Atropa belladonna. The biosynthesis of these compounds is thought to take place via the tropane alkaloid pathway, the ... analyses having revealed the presence of the tropane alkaloid tropinone and the pyrrolidine alkaloid hygrine (0.1%, in the root ... It is not yet known whether this mild psychoactivity is referable to the alkaloid content or the withanolide content (or ... Also present in Nicandra are calystegines, a new group of polyhydroxy alkaloids with a nortropane skeleton and named for the ...
Psychochemical warfare
... that contain combinations of anticholinergic alkaloids. In 184 B.C., Hannibal's army used belladonna plants to induce ...
Witches' Sabbath
... most commonly Atropa belladonna (Deadly Nightshade) and Hyoscyamus niger (Henbane), belonging to the tropane alkaloid-rich ... The alkaloids Atropine, Hyoscyamine and Scopolamine present in these Solanaceous plants are not only potent and highly toxic ...
Cuscohygrine
Pyrrolidine alkaloids, Alkaloids found in Erythroxylum coca, Alkaloids found in Solanaceae, Ketones). ... It can also be extracted from plants of the family Solanaceae, including Atropa belladonna (deadly nightshade), Datura innoxia ... Cuscohygrine, along with the related metabolite hygrine, was first isolated by Carl Liebermann in 1889 as an alkaloid ... It also forms a crystalline trihydrate which melts at 40-41 °C. Coca alkaloids Dihydrocuscohygrine "USDA, ARS, National Genetic ...
List of wort plants
Produces escharotic alkaloids that corrode skin, leaving wounds. More commonly known as bloodroot, or sometimes tetterwort. ... Banewort - Ranunculus flammula or Atropa belladonna Barrenwort - Epimedium, especially Epimedium alpinum. Bearwort - Meum ...
Hyoscyameae
... showing curled stamens Atropa belladonna in fruit : ripe and unripe berries Atropa belladonna ripe berry in close-up Anatomy of ... being rich in tropane alkaloids with anticholinergic properties. Furthermore, the genera Atropa, Hyoscyamus, Scopolia and ... Atropa belladonna flower and berry Botanical illustration of Atropa baetica, Andalusian belladonna Scopolia carniolica: two ... as has frequently occurred in the case of Atropa belladonna, the infamous Deadly Nightshade. A ninth genus referable to ...
Potato
Like all parts of the plant except the tubers, the fruit contain the toxic alkaloid solanine and are therefore unsuitable for ... Atropa belladonna), henbane (Hyoscyamus niger) and tobacco (Nicotiana spp.), as well as the food plants eggplant and tomato. ...
Physostigmine
Alkaloids, Aromatic carbamates, Pyrroles, Pyrroloindoles, Secondary amines, Alkaloids found in Fabaceae, Plant toxins, ... It is also an antidote for Atropa belladonna poisoning, the same as for atropine. It has also been used as an antidote for ... The metabolite thus formed from physostigmine and some other alkaloids (e.g. cymserine) is eseroline, which research has ... 3rd edition Roberts MF, Wink M (1998). Alkaloids: Biochemistry, Ecology, and Medicinal Applications. Plenum Press. p. 38. ISBN ...
Hippeastrum
... and psychopharmacological activity due to their high alkaloid content. One alkaloid isolated from Hippeastrum vittatum ( ... This was assumed to be the South African Cape Belladonna, although not precisely known. Clifford's herbarium is now preserved ... Tjaden, W. L. (November 1979). "Amaryllis belladonna and the Guernsey lily: an overlooked clue". Journal of the Society for the ... Dyer, R. A. (1954). "The Cape Belladonna Lily". Taxon. 3 (2): 72-74. doi:10.2307/1217368. JSTOR 1217368. Ephrath, J.E.; Ben- ...
Atropa pallidiflora
... differs from Atropa belladonna chiefly in its glabrescence (lack of hairs), also in its narrower leaves, ... containing a variety of tropane alkaloids valued in medicine for their anticholinergic, antispasmodic and mydriatic properties ...
Plant secondary metabolism
Atropine is a type of secondary metabolite called a tropane alkaloid. Alkaloids contain nitrogens, frequently in a ring ... Within Atropa belladonna atropine synthesis has been found to take place primarily in the root of the plant. The concentration ... "Synthesis of Atropine by Isolated Roots and Root-Callus Cultures of Belladonna." Botanical Gazette: Vol. 119, No. 1 (Sep., 1957 ... Well known specialized compounds include alkaloids, polyphenols including flavonoids, and terpenoids. Humans use many of these ...
History of malaria
Physicians and surgeons in the period used herbal medicines like belladonna to bring about pain relief in affected patients. ... It would be nearly 200 years before the active principles, quinine and other alkaloids, of cinchona bark were isolated. Quinine ... Butler's Saint for the Day (Paul Burns), Liturgical Press, p. 516 "Belladonna". Medline Plus. 16 December 2009. Archived from ... French chemist Pierre Joseph Pelletier and French pharmacist Joseph Bienaimé Caventou separated in 1820 the alkaloids ...
Caffeine
Graham JR (June 1954). "Rectal use of ergotamine tartrate and caffeine alkaloid for the relief of migraine". The New England ... Runge was invited to show Goethe how belladonna caused dilation of the pupil, which Runge did, using a cat as an experimental ... Caffeine is a bitter, white crystalline purine, a methylxanthine alkaloid, and is chemically related to the adenine and guanine ... Frischknecht PM, Ulmer-Dufek J, Baumann TW (1986). "Purine alkaloid formation in buds and developing leaflets of Coffea arabica ...
Amaryllidaceae
A number of tropical lily-like plants are also sold, such as the belladonna lily, Amazon lily, blood lily (Cape tulip), Cornish ... Takos, Adam; Rook, Fred (31 May 2013). "Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in ...
Religion and drugs
The seeds of this powerful narcotic, termed "passion seeds" (candabija), are the strongest elements and contain the alkaloids ... In even moderate doses, datura can render a person virtually immobile with severe belladonna-like hallucinations." In the ...
Scopolia
... belladonna ssp. caucasica. Corolla shape: Scopolia carniolica, simple, un-lobed, straight-sided bell / Atropa belladonna ... Other alkaloids found in Scopolia carniolica include cuscohygrine, hyoscyamine and atroscine. The coumarin phenylpropanoids ... Calyx type: Scopolia carniolica, cup-shaped, with slight peaks rather than distinct lobes / Atropa belladonna distinctly lobed ... Other points of dissimilarity include: Pedicel type: Scopolia carniolica, long, slender and delicate / Atropa belladonna, ...
Laudanum
... is known as a "whole opium" preparation since it historically contained all the alkaloids found in the opium poppy, ... belladonna, whiskey, wine and brandy.": 104 As one researcher has noted: "To understand the popularity of a medicine that eased ... The quantity of the papaverine and codeine alkaloids in opium tincture is too small to have any demonstrable central nervous ... Each mL contains 10 mg of anhydrous morphine (the equivalent of 100 mg of powdered opium), other opium alkaloids (except ...
List of psychoactive plants, fungi, and animals
Atropa belladonna) Henbane (Hyoscyamus niger) Mandrake (Mandragora officinarum) Other Solanaceae Psychoactive cacti, which ... nicotine and beta-carboline alkaloids Coca: cocaine Opium Poppy: morphine, codeine, thebaine, papaverine, noscapine, and ...
Iochroma arborescens
Raffauf, R.F. A Handbook of Alkaloids and Alkaloid-Containing Plants 1970 Barata L. et al.Chem. Abstr. 75 (1971) 115901 ... belladonna' and showing anatomy of flower and fruit of Acnistus arborescens. Acnistus arborescens, cultivated plant, Lankester ... Ayensu (1981) lists alkaloids, glycosides, organic acids, saponins and tannins as constituents of plant material collected in ... An alkaloid, acnistine is also sometimes present, studies having indicated that this widespread tropical American species ...
Atropine
... is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide ... Atropine occurs naturally in a number of plants of the nightshade family, including deadly nightshade (belladonna), Jimson weed ...
Solanum
Deadly nightshade (Atropa belladonna) belongs, like Solanum, to subfamily Solanoideae of the nightshade family, but, unlike ... The chemistry of Atropa species is very different from that of Solanum species and features the very toxic tropane alkaloids, ...
Anticholinergic
The most common plants containing anticholinergic alkaloids (including atropine, scopolamine, and hyoscyamine among others) are ... Atropa belladonna (deadly nightshade) Brugmansia species Datura species Garrya species Hyoscyamus niger (henbane) Mandragora ... Nondepolarizing skeletal muscular relaxant Plants of the family Solanaceae contain various anticholinergic tropane alkaloids, ...
Belladonna Alkaloid Combinations and Phenobarbital: MedlinePlus Drug Information
Belladonna Alkaloid Combinations and Phenobarbital: learn about side effects, dosage, special precautions, and more on ... Take belladonna alkaloid combinations and phenobarbital exactly as directed. Do not take more or less of it or take it more ... Belladonna alkaloid combinations and phenobarbital come as a regular tablet, a slow-acting tablet, capsule, and liquid to take ... Before taking belladonna alkaloid combinations and phenobarbital,. *tell your doctor and pharmacist if you are allergic to ...
DailyMed - Search Results for Scopolamine
BELLADONNA ALKALOIDS WITH PHENOBARTBITAL tablet. NDC Code(s): 68645-230-59 *Packager: Legacy Pharmaceutical Packaging ... PHENOBARBITAL WITH BELLADONNA ALKALOIDS elixir. NDC Code(s): 42291-205-04, 42291-205-16 *Packager: AvKARE ... PHENOBARBITAL WITH BELLADONNA ALKALOIDS (phenobarbital, hyoscyamine sulfate, atropine sulfate, scopolamine hydrobromide) tablet ...
Pediatric Status Epilepticus: Practice Essentials, Background, Pathophysiology
Anticholinergic Poisoning Associated
with an Herbal Tea -- New York City, 1994
From 1 uL of the liquid extract, the belladonna alkaloids atropine, scopolamine, and hyoscyamine were identified by gas ... Because a large number of plants throughout the United States contain belladonna alkaloids, plants harvested for human ... The leaves contain caffeine, theophylline, and a nontoxic volatile oil but do not contain belladonna alkaloids. ... are characteristic of the anticholinergic effects associated with poisoning by belladonna alkaloids (1). In addition, patients ...
MedlinePlus - Search Results for: Phenobarbital
DailyMed - HYDROXYZINE HYDROCHLORIDE tablet, film coated
physostigmine) dosing, indications, interactions, adverse effects, and more
belladonna alkaloids. Monitor Closely (1)physostigmine increases and belladonna alkaloids decreases cholinergic effects/ ... belladonna alkaloids. physostigmine increases and belladonna alkaloids decreases cholinergic effects/transmission. Effect of ... belladonna and opium. Monitor Closely (1)physostigmine increases and belladonna and opium decreases cholinergic effects/ ... belladonna and opium. physostigmine increases and belladonna and opium decreases cholinergic effects/transmission. Effect of ...
Cyclogyl 1 % eye drops | Kaiser Permanente
MeSH Browser
Alkaloids [D03.132] * Solanaceous Alkaloids [D03.132.760] * Belladonna Alkaloids [D03.132.760.180] * Atropine Derivatives [ ... Alkaloids [D03.132] * Tropanes [D03.132.889] * Belladonna Alkaloids [D03.132.889.180] * Atropine Derivatives [D03.132.889.180. ... Belladonna Alkaloids Preferred Concept UI. M0002300. Registry Number. 0. Scope Note. Alkaloids obtained from various plants, ... Belladonna Alkaloids Preferred Term Term UI T004445. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ...
Hyoscyamine - LiverTox - NCBI Bookshelf
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion ... Common brand names for products that include hyoscyamine are Belladonna Alkaloids, Donnatal, Hyomax, Urogesic, and Cyclospaz. ... Hyoscyamine (hye" oh sye a meen) is a derivative of natural alkaloid found in plants of the Solanacea family such as henbane ( ... Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion ...
Ulcer Remedies
Betaxolol Hydrochloride|N0000004400
Belladonna Alkaloids,N0000005785, Disopyramide,N0000005784, Ammonia,N0000005783, Corn Oil,N0000005782, Cromolyn Sodium, ... Indole Alkaloids,N0000011188, Secologanin Tryptamine Alkaloids,N0000011187, Aminohippuric Acids,N0000011186, p-Aminohippuric ... Veratrum Alkaloids,N0000008188, Clavulanic Acids,N0000008078, Platelet-Derived Growth Factor,N0000008077, Extracellular Matrix ... Vinca Alkaloids,N0000007780, Iodides,N0000007779, Iodamide,N0000007778, Homosteroids,N0000007777, Myristic Acids,N0000007776, ...
National Hospital Ambulatory Medical Care Survey, 1995
BELLADONNA ALKALOIDS W/PHENOBARBITAL 03845 BELLERGAL 03850 BELLERGAL-S 03870 BELLOPHEN 03885 BEMINAL 03900 BEN GAY 03905 ... 1481 Antimetabolites 1482 Antibiotics,Alkaloids,Enzymes 1483 DNA Damaging Drugs 1500 OPHTHALMICS 1566 Glaucoma 1567 ... BELLADONNA 50497 BEMEGRIDE 50498 BENAZEPRIL HYDROCHLORIDE 50499 BENACTYZINE 50500 BENDROFLUMETHIAZIDE 50502 BENOXAPROFEN 50505 ...
Scientists genetically modify tobacco plant that makes cocaine
But although the biosynthesis of the related tropane alkaloid, atropine, from belladonna (Solanaceae) is well-established, not ... And since tropane alkaloids also serve as the lead compounds to generate more effective drugs, they are listed in the World ... Tropane alkaloids like cocaine are mainly produced by two families of plants: Solanaceae (tomato, tobacco, potato relatives) ... But despite the wide appeal of this drug, scientists are still figuring out how this complex tropane alkaloid is produced in ...
DeCS
Belladonna Alkaloids - Preferred Concept UI. M0002300. Scope note. Alkaloids obtained from various plants, especially the ... Belladonna (1968-1974). Tropanes (1968-1974). Public MeSH Note:. 76; was see under BELLADONNA 1975-76, was see under TROPANES ... Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variety acuminata; atropine, ... Alcaloides que se obtienen de diversas plantas, especialmente la solanácea mortal (Atropa belladonna), variedad acuminata; la ...
MeSH Browser
Alkaloids [D03.132] * Solanaceous Alkaloids [D03.132.760] * Belladonna Alkaloids [D03.132.760.180] * Atropine Derivatives [ ... Alkaloids [D03.132] * Tropanes [D03.132.889] * Belladonna Alkaloids [D03.132.889.180] * Atropine Derivatives [D03.132.889.180. ... Belladonna Alkaloids Preferred Concept UI. M0002300. Registry Number. 0. Scope Note. Alkaloids obtained from various plants, ... Belladonna Alkaloids Preferred Term Term UI T004445. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ...
Synergistic effects of polyploidization and elicitation on biomass and hyoscyamine content in hairy roots of Datura stramonium ...
Differential production of tropane alkaloids in hairy roots and in vitro cultured two accessions of Atropa belladonna L. under ... Alkaloid spectrum in diploid and tetraploid hairy root cultures of Datura stramonium. Z. Naturforsch., C: Biosci., 58(1/2), 42- ... Size and alkaloid content of seeds in induced autotetraploids of Datura innoxia, Datura stramonium and Hyoscyamus niger. Pharm ... Production of tropane alkaloids in diploid and tetraploid plants and in vitro hairy root cultures of Egyptian henbane ( ...
SAS VALUE LABELS FOR 2007 NHHCS PUBLIC USE FILE
BELLADONNA 03805=BELLADONNA ALKALOIDS W/PHENOBARBITAL 03885=BEMINAL 03900=BEN-GAY 03903=BENA-D 03905= ... L-ALKALOIDS OF BELLADONNA; PHENOBARBITAL a10984=CHLORAMINE-T-SODIUM P-TOLUENE-SULFONCHLORA a10988=L-METHYLFOLATE; ... OPIUM AND BELLADONNA 21893=OPTICROM 21958=ORAP 21995=ORETIC 22025=ORIMUNE POLIOVIRUS VAC LIVE ORAL 22065= ... BELLADONNA-OPIUM d03437=APAP; ASA; CAFFEINE; SALICYLAMIDE d03439=APAP; ASA; CAFFEINE d03445=ACETAMINOPHEN- ...
2023 Drugs Underdosing ICD-10-CM Codes
Belladonna [See Also: Nightshade]alkaloids; Belladonna [See Also: Nightshade]extract; Belladonna [See Also: Nightshade]herb; ... Laudanum; Opium alkaloids (total); Opium alkaloids (total)standardized powdered; Opium alkaloids (total)tincture (camphorated ... Cinchonine alkaloids; Cycloguanil embonate; Daraprim; Eflornithine; Guanatol; Halofantrine; Isopentaquine; Mefloquine; ...
E0000163|Adriamycin|doxorubicin
NRS: CHAPTER 454 - POISONS; DANGEROUS DRUGS AND HYPODERMICS
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Pesquisa | Portal Regional da BVS
Alkaloid profiles from Amaryllis belladonna plants collected in Chile were examined by GC-MS to assess their inhibitory ... Overall, our study supports the potential use of A. belladonna as an alkaloid source with AChE inhibitory activity.[Formula: ... expanding the role of delta-class GSTs towards alkaloids. Likewise, GST inhibition by alkaloid analogs is proposed in the ... The alkaloid extract (ALKE) was obtained by acid-base extraction. N-formyl loline (NFL) and N-acetyl loline (NAL) were isolated ...
Atropine7
- From 1 uL of the liquid extract, the belladonna alkaloids atropine, scopolamine, and hyoscyamine were identified by gas chromatography/mass spectrometry. (cdc.gov)
- Atropine and other belladonna alkaloids are not affected by the drug. (nih.gov)
- But although the biosynthesis of the related tropane alkaloid, atropine, from belladonna ( Solanaceae ) is well-established, not nearly enough is known about the formation of cocaine. (zmescience.com)
- The action of belladonna upon the system is that of atropine. (drugstoremuseum.org)
- Both morphine and pilocarpine are to some extent physiologically antagonistic to atropine, and have been found very useful in belladonna poisoning. (drugstoremuseum.org)
- Belladonna should never be given in substance, but in the form of extract or tincture, or, when accuracy or quickness of action is desired, of atropine. (drugstoremuseum.org)
- CAS Number 51-55-8] Atropine is the synthetically-derived form of the naturally occurring alkaloid found in the plant Atropa belladonna. (lipomed-usa.com)
Hyoscyamine11
- Hyoscyamine, one of the principal alkaloid components of belladonna, is a potent anticholinergic agent. (nih.gov)
- This study not only reports a near-complete biosynthetic pathway of cocaine and provides new insights into the metabolic networks of tropane alkaloids (cocaine and hyoscyamine) in plants but also enables the heterologous synthesis of tropane alkaloids in other (micro)organisms, entailing significant implications for pharmaceutical production," the authors said. (zmescience.com)
- En effet, les CRs de Datura stramonium ont été largement étudiés dans la perspective de l'amélioration du rendement en hyoscyamine. (ac.be)
- Ce document vise à étudier les effets de la polyploïdisation des CRs induits par la colchicine en synergie avec l'élicitation (avec des acides acétylsalicylique ou salicylique) sur la teneur en hyoscyamine de D. stramonium . (ac.be)
- Les effets de la polyploïdisation et de l'élicitation ont été étudiés sur la biomasse (poids sec) et la teneur en hyoscyamine des CRs. (ac.be)
- En outre, la lignée de CR tétraploïde montre une augmentation de sa biomasse et de son contenu en hyoscyamine par rapport à la lignée diploïde de CR (LDS). (ac.be)
- Cependant, les mêmes traitements montrent une augmentation significative du rendement en hyoscyamine dans les lignées de CRs élicitées. (ac.be)
- Par conséquent, notre travail indique que la combinaison de la polyploïdie et de l'élicitation peut conduire à des améliorations significatives dans la biosynthèse et le contenu en hyoscyamine en raison de leurs effets synergiques. (ac.be)
- L'élicitation de lignées tétraploïdes de chevelus racinaires améliore considérablement leur teneur en hyoscyamine. (ac.be)
- The hyoscyamine, a tropane alkaloid, widely used in medicine, can be produced from Datura sp. (ac.be)
- HYOSCYAMINE SULFATE is an alkaloid of belladonna. (nih.gov)
Tropane alkaloids4
- And since tropane alkaloids also serve as the lead compounds to generate more effective drugs, they are listed in the World Health Organization's list of essential medicines and are available in the market with FDA approval. (zmescience.com)
- Theoretically, they could add these genes to high-growth rate microorganisms like the bacterium E. coli and the yeast Saccharomyces cerevisia e to produce tropane alkaloids in industrial quantities inside bioreactor tanks. (zmescience.com)
- It must, however, be handled with great care: it is highly toxic as it contains considerable quantities of tropane alkaloids, similar to Hyoscyamus niger or Atropa belladonna . (herbresearch.de)
- 3) Grynkiewicz G, Gadzikowska M. Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs. (herbresearch.de)
Scopolamine1
- Scopolamine, Belladonna (Hyoscine Hydrobromide) 0.3 to 0.65 mg administered IV, intramuscularly or subcutaneously every 6 to 8 hours as needed 1.5 mg transdermal disc behind the ear every 3 days:What is the Motion Sickness patch? (primafitt.eu)
ATROPA BELLADONNA5
- Seizures caused by ingestion of Atropa belladonna in a homeopathic medicine in a previously well infant: case report and review of the literature. (nih.gov)
- Some species in this genus are called deadly nightshade which is also a common name for ATROPA BELLADONNA. (umassmed.edu)
- The dried leaves of Atropa Belladonna Linne (Fam. (drugstoremuseum.org)
- U.S. " The fresh leaves and branches of Atropa Belladonna, Linn. (drugstoremuseum.org)
- U. S. " The root of Atropa Belladonna, Linn. (drugstoremuseum.org)
Pharmacist if you are allergic1
- tell your doctor and pharmacist if you are allergic to belladonna, any barbiturate medicine, tartrazine (a yellow dye in some processed foods and drugs), or any drug. (medlineplus.gov)
Phenobarbital6
- Belladonna alkaloid combinations and phenobarbital are used to relieve cramping pains in conditions such as irritable bowel syndrome and spastic colon. (medlineplus.gov)
- Belladonna alkaloid combinations and phenobarbital come as a regular tablet, a slow-acting tablet, capsule, and liquid to take by mouth. (medlineplus.gov)
- Take belladonna alkaloid combinations and phenobarbital exactly as directed. (medlineplus.gov)
- If you have any of these symptoms, stop taking belladonna alkaloids and phenobarbital and call your doctor immediately. (medlineplus.gov)
- If you become pregnant while taking belladonna alkaloids and phenobarbital, call your doctor. (medlineplus.gov)
- Older adults should receive low doses of belladonna and phenobarbital because higher doses do not function better and can cause serious side effects. (medlineplus.gov)
Cocaine4
- Sheng-Xiong Huang of the Kunming Institute of Botany in China and colleagues found that two key enzymes, En CYP81AN15 and En MT4, are fundamental to the key chemical pathway that Erythroxylum novogranatense (the coca plant) uses to make cocaine. (zmescience.com)
- CAS Number 50-36-2] Cocaine, known by street names such as blow, coke, and snow, is a tropane alkaloid derived from the leaves of the coca plant. (lipomed-usa.com)
- CAS Number 53-21-4] Cocaine.hydrochloride known by street names such as coke and snow, is the hydrochloride salt form of the tropane alkaloid cocaine derive. (lipomed-usa.com)
- CAS Number 5796-31-6] Ecgonine.hydrochloride, a tropane alkaloid derived from the coca plant leaves, is both a primary precursor of cocaine and a metabolite. (lipomed-usa.com)
Anticholinergic1
- Inadvertent anticholinergic poisoning can result from consumption of foods contaminated with plants that contain belladonna alkaloids. (cdc.gov)
Opium1
- physostigmine increases and belladonna and opium decreases cholinergic effects/transmission. (medscape.com)
Coca plant1
- But despite the wide appeal of this drug, scientists are still figuring out how this complex tropane alkaloid is produced in the coca plant. (zmescience.com)
Considerable1
- Belladonna has acquired considerable credit as a preventive of scarlatina,- an application of the remedy first suggested by the author of the homoeopathic doctrine,- but it is absolutely devoid of any such power. (drugstoremuseum.org)
Toxic1
- infants and young children are especially susceptible to the toxic effect of the belladonna alkaloids. (nih.gov)
Found2
- Peel all potatoes since the highest concentration is of alkaloids are found in the skin. (wilddingo.com)
- Interestingly enough, Capsaicin, the alkaloid found in hot peppers (such as chilies), actually causes the reverse effect, triggering such a strong immune response that it results in a strong anti-inflammatory benefit. (wilddingo.com)
Higher1
- Avoid green tomatoes or sprouting potatoes as unripe nightshades are higher in alkaloids. (wilddingo.com)
Root1
- of the alkaloids of belladonna root. (nih.gov)
Total2
- The prophylaxis of carbon tetrachloride hepatotoxicity by total belladonna alkaloids. (nih.gov)
- Analysis of samples from two shipments of colloidum belladonna showed that one contained not less than 0.517 percent of the total alkaloids of belladonna, and the other contained not less than 0.57 percent of the total alkaloids of bella- donna. (nih.gov)
Medicine1
- Belladonna has been used as a medicine from early times. (drugstoremuseum.org)
Percent2
- Analysis of a sample of colloidum ipecacuanha, showed that it contained not less than 1.32 percent of the ether soluble alkaloids of ipecac. (nih.gov)
- The article was alleged to be adulterated in that its strength differed from that which it purported and was represented to possess, that is, not more than 1 percent of the ether soluble alkaloids of ipecac, whereas it contained 1.32 percent of the either soluble alkaloids of ipecac. (nih.gov)
Similar1
- Bella donna atropa is eerily similar to garden huckleberry above, but the belladonna berries aren't clustered like the huckleberry. (wilddingo.com)