Behcet Syndrome: Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.Panniculitis, Nodular Nonsuppurative: A form of panniculitis characterized by recurrent episodes of fever accompanied by the eruption of single or multiple erythematous subcutaneous nodules on the lower extremities. They normally resolve, but tend to leave depressions in the skin. The condition is most often seen in women, alone or in association with other disorders.Erythema Nodosum: An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.Syndrome: A characteristic symptom complex.Philately: Study of stamps or postal markings. It usually refers to the design and commemorative aspects of the stamp.Numismatics: Study of coins, tokens, medals, etc. However, it usually refers to medals pertaining to the history of medicine.Epididymitis: Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.Mesenteric Artery, Inferior: The artery supplying nearly all the left half of the transverse colon, the whole of the descending colon, the sigmoid colon, and the greater part of the rectum. It is smaller than the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) and arises from the aorta above its bifurcation into the common iliac arteries.EponymsSkin Diseases, Vascular: Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area.Aneurysm: Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.HLA-B51 Antigen: A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*51 allele family.Penicillin G Benzathine: Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.Varicocele: A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)Metabolic Syndrome X: A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)Stomatitis, Aphthous: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.Oral Ulcer: A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)HLA-B52 Antigen: A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*52 allele family.Conjunctival DiseasesClick Chemistry: Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Calcium-Calmodulin-Dependent Protein Kinases: A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also sometimes dependent on CALCIUM. A wide range of proteins can act as acceptor, including VIMENTIN; SYNAPSINS; GLYCOGEN SYNTHASE; MYOSIN LIGHT CHAINS; and the MICROTUBULE-ASSOCIATED PROTEINS. (From Enzyme Nomenclature, 1992, p277)Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Microtubule-Associated Proteins: High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Annual Reports as Topic: Annual statements reviewing the status of the administrative and operational functions and accomplishments of an institution or organization.Californium: Californium. A man-made radioactive actinide with atomic symbol Cf, atomic number 98, and atomic weight 251. Its valence can be +2 or +3. Californium has medical use as a radiation source for radiotherapy.Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.Annual ReportsDemyelinating Autoimmune Diseases, CNS: Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.Theilovirus: A species of CARDIOVIRUS which contains three strains: Theiler's murine encephalomyelitis virus, Vilyuisk human encephalomyelitis virus, and Rat encephalomyelitis virus.Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.Rosacea: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).Drug Eruptions: Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. These may assume various morphologic patterns and produce various types of lesions.Skin Tests: Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.Helianthus: A genus herbs of the Asteraceae family. The SEEDS yield oil and are used as food and animal feed; the roots of Helianthus tuberosus (Jerusalem artichoke) are edible.Musculoskeletal Diseases: Diseases of the muscles and their associated ligaments and other connective tissue and of the bones and cartilage viewed collectively.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Panuveitis: Inflammation in which both the anterior and posterior segments of the uvea are involved and a specific focus is not apparent. It is often severe and extensive and a serious threat to vision. Causes include systemic diseases such as tuberculosis, sarcoidosis, and syphilis, as well as malignancies. The intermediate segment of the eye is not involved.Malpractice: Failure of a professional person, a physician or lawyer, to render proper services through reprehensible ignorance or negligence or through criminal intent, especially when injury or loss follows. (Random House Unabridged Dictionary, 2d ed)Insurance, Liability: Insurance against loss resulting from liability for injury or damage to the persons or property of others.Liability, Legal: Accountability and responsibility to another, enforceable by civil or criminal sanctions.Community Health Centers: Facilities which administer the delivery of health care services to people living in a community or neighborhood.Lawyers: Persons whose profession is to give legal advice and assistance to clients and represent them in legal matters. (American Heritage Dictionary, 3d ed)Insurance Carriers: Organizations which assume the financial responsibility for the risks of policyholders.Iridocyclitis: Acute or chronic inflammation of the iris and ciliary body characterized by exudates into the anterior chamber, discoloration of the iris, and constricted, sluggish pupil. Symptoms include radiating pain, photophobia, lacrimation, and interference with vision.Blister: Visible accumulations of fluid within or beneath the epidermis.Eye Pain: A dull or sharp painful sensation associated with the outer or inner structures of the eyeball, having different causes.Scrotum: A cutaneous pouch of skin containing the testicles and spermatic cords.Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.

Autoantibodies to T cell costimulatory molecules in systemic autoimmune diseases. (1/725)

To determine whether antilymphocyte Abs to T cell costimulatory molecules are generated in patients with autoimmune diseases and, if they exist, to clarify the mechanism of their production and pathological roles, we investigated the presence of autoantibodies to CTLA-4 (CD152), CD28, B7-1 (CD80), and B7-2 (CD86) in serum samples obtained from patients with various autoimmune diseases and from normal subjects using recombinant fusion proteins. In ELISAs, anti-CD28, anti-B7-1, and anti-B7-2 Abs were rarely seen, whereas anti-CTLA-4 Abs were detected in 8.2% of the patients with systemic lupus erythematosus, 18.8% of those with rheumatoid arthritis, 3.1% of those with systemic sclerosis, 31.8% of those with Behcet's disease, 13.3% of those with Sjogren's syndrome, and 0% of healthy donors. This reactivity was confirmed by immunoblotting. More importantly, the purified anti-CTLA-4 Abs reacted with CTLA-4 expressed on P815 cells by flow cytometry. In addition, we found at least three epitopes on the CTLA-4 molecule. Furthermore, among the patients with Behcet's disease, uveitis was seen significantly less frequently in the anti-CTLA-4 Ab-positive patients. Taken collectively, these data indicate that anti-CTLA-4 autoantibodies are generated in systemic autoimmune diseases by an Ag-driven mechanism and may modulate the immune response in vivo by binding to CTLA-4 on T cells.  (+info)

The critical region for Behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping. (2/725)

The HLA-B51 allele is known to be associated with Behcet disease. Recently, we found a higher risk for Behcet disease in the MICA gene, 46 kb centromeric of HLA-B, by investigation of GCT repetitive polymorphism within exon 5 of MICA. The pathogenic gene causing Behcet disease, however, has remained uncertain. Here, eight polymorphic microsatellite markers, distributed over a 900-kb region surrounding the HLA-B locus, were subjected to association analysis for Behcet disease. Statistical studies of associated alleles detected on each microsatellite locus showed that the pathogenic gene for Behcet disease is most likely found within a 46-kb segment between the MICA and HLA-B genes. The results of this mapping study, and the results of an earlier study of ours, suggest that MICA is a strong candidate gene for the development of Behcet disease.  (+info)

Behcet's disease sera containing antiendothelial cell antibodies promote adhesion of T lymphocytes to cultured human dermal microvascular endothelial cells. (3/725)

Antiendothelial cell antibodies (AECA) have been detected in the sera of patients of autoimmune diseases showing vasculitis. Using IgM-ELISA, we found AECA in 42 (56%) of 75 sera samples from patients with Behcet's disease in a previous study. All of the 15 AECA-positive sera of Behcet's disease patients had an increased expression of the intercellular cell adhesion molecule-1 (ICAM-1), 93.3% of the sera induced the vascular cell adhesion molecule-1 (VCAM-1), and 100% of the serum induced the E-selectin molecule on human dermal microvascular endothelial cells (HDMEC). After stimulation of HDMEC with AECA-positive sera of Behcet's disease patients, the expression of ICAM-1 and VCAM-1 on HDMEC increased significantly at 4 hours, reaching a peak at 16 hours. Expression of E-selectin was induced at 1 hour after stimulation with a peak at 4 hours and it decreased thereafter. Adherence of T lymphocytes to HDMEC increased significantly after stimulation with AECA-positive sera from Behcet's disease patients. Also, the adherence of T lymphocytes to HDMEC increased at 4 hours and returned to its normal level at 48 hours. These results show that AECA-positive sera of Behcet's disease patients are capable of activating HDMEC to promote the adherence of T lymphocytes to increase the expression of ICAM-1, VCAM-1, and E-selectin on the cell surfaces. The whole process may play an important role in the pathogenesis of vasculitis in Behcet's disease.  (+info)

Childhood Behcet's disease: clinical features and comparison with adult-onset disease. (4/725)

OBJECTIVE: To study the clinical spectrum of Behcet's disease (BD) in childhood, in comparison to adult-onset disease. METHODS: Nineteen children, who fulfilled disease criteria up to the age of 16 yr, were studied. The results were compared to those of 34 adult patients with BD. An activity index and severity score were calculated for both study groups. RESULTS: The mean age of disease onset was 6.9+/-3.9 yr, similar ages of onset were found in males and females. The clinical spectrum of childhood BD resembled that of adult disease; however, the prevalence of certain manifestations was different between children and adults. Children with BD had significantly less genital ulcers, less vascular thromboses and more non-specific gastrointestinal symptoms, as well as central nervous system involvement and arthralgia. A relatively high prevalence of uveitis was found in childhood BD. The activity index and severity score were significantly lower in children than in adults. CONCLUSION: Our results point to a similar systemic expression of BD in children and adults; however, the disease seems to run a less severe course in children.  (+info)

Anti-Sa antibody in Chinese rheumatoid arthritis. (5/725)

OBJECTIVE: To test anti-Sa antibody in different autoimmune connective tissue diseases and analyze the relationship between Sa antibody and clinical manifestations and laboratory tests in rheumatoid arthritis. METHOD: Sa antigen was extracted from human placenta. Anti-Sa antibody was tested in 40 normal people and 478 connective tissue disease (CTD) patients using Western Blotting (WB). RESULTS: Sa antigen was a protein with molecular weights of 50 kD and 55 kD. Anti-Sa antibody was positive in 31.9% (61/191) rheumatoid arthritis (RA), 3.0% (2/67) Sjogren's syndrome (SS), 4.3% (2/46) systemic lupus erythmatosus (SLE) and 0% (0/66) Behcet's disease, 0% (0/60) polymyositis/dermatomyositis (PM/DM), 0% (0/66) other CTD and 0% (0/40) normal controls. Anti-Sa antibody was different from other auto-antibodies in RA. In rheumatoid arthritis its sensitivity, specificity, positive prediction rate, negative prediction rate were 31.9%, 98.6%, 93.8% and 68.5% respectively. Anti-Sa antibody positive patients were significantly different from anti-Sa antibody negative patients in moming stiffness, ESR, ANA and X-ray grade. CONCLUSION: Anti-Sa antibody was a new auto-antibody for the diagnosis of RA. Anti-Sa antibody positive patients seem to have more serious inflammation and more advanced disease process.  (+info)

Oligoclonal T cell expansions in patients with Behcet's disease. (6/725)

Behcet's disease (BD) is a multisystem disorder with oral and genital ulcers, mucocutaneous, ocular, joint, vascular and central nervous system involvement. In this study, the peripheral T cell repertoire was analysed in patients with BD with MoAbs against T cell receptor (TCR) Vbeta gene products in CD4+ and CD8+ T cell compartments, and these were compared with rheumatoid arthritis (RA) patients and healthy controls (HC). In the CD4+ T cell compartment, oligoclonal TCR Vbeta expression was observed in 56% of BD (10/18), 71% of RA (5/7) patients and 21% (3/14) of HC. In the CD8+ T cell group 50% of BD (9/18), 57% of RA patients and 28% of HC (4/14) had an oligoclonal TCR repertoire. An increase of TCR Vbeta5.1 subset was observed in five BD patients among CD8+ T cells. Other elevations of TCR Vbeta subsets were heterogeneously distributed with one to three different Vbeta subsets. Our results suggest an antigen-driven oligoclonal increase of T cells in BD. There was no overall increase in any Vbeta group to suggest a superantigen effect. Analysis of the responsible antigens causing the increase in T cell subsets may give insights into the aetiopathogenesis of BD and immunomodulation of these T cells may lead to new treatments.  (+info)

Neuro-Behcet's disease presenting with isolated unilateral lateral rectus muscle palsy. (7/725)

The authors present the clinical findings of a 30-year-old female and a 29-year-old male who both had isolated unilateral lateral rectus muscle palsy in neuro-Behcet's disease. The clinical feature related to isolated abduscens nerve palsy was identified by CT, systemic assessment and extraocular examination. These patients' constellation of findings appear to be unique: it does not follow any previously reported pattern of ocular manifestations of neuro-Behcet's disease.  (+info)

Association of MICA gene and HLA-B*5101 with Behcet's disease in Greece. (8/725)

PURPOSE: Behcet's disease (BD) is known to be associated with HLA-B51 in many different ethnic groups. Recently MICA, a member of a novel family of the human major histocompatibility complex (MHC) class I genes termed MIC (MHC class I chain-related genes), was identified near the HLA-B gene, and a triplet repeat microsatellite polymorphism was found in the transmembrane (TM) region. Because a strong association with BD of one particular MICA-TM allele, A6, was shown in a Japanese population, the present study was conducted to investigate microsatellite polymorphism in Greek patients with BD to know whether this association is generally observed in BD occurring in other populations. METHODS: Thirty-eight Greek patients with BD and 40 ethnically matched control subjects were examined for MICA microsatellite polymorphism using polymerase chain reaction (PCR) and subsequent automated fragment detection by fluorescent-based technology. RESULTS: Similar to the Japanese patients with BD, the phenotype frequency of the MICA-TM A6 allele was significantly increased in the Greek patients with BD (50.0% in control subjects versus 86.8% in BD cases), with an odds ratio (OR) of 6.60 (P = 0.0012). The MICA-A6 allele was found in a high frequency both in males and females (weighted OR = 6.68; P = 0.0017). No association was found between the A6 allele and several disease features. A strong association exists between the MICA-TM A6 allele and the B*5101 allele in both the control subjects and patients with BD (weighted OR = 44.39; P = 0.0000023). CONCLUSIONS: This study revealed in Greek patients a strong association of BD with a particular MICA-TM allele, MICA-A6, providing insight into the molecular mechanism underlying the development of BD.  (+info)

Objective: Behcets disease is a chronic inflammatory vasculitis. Vascular involvement is one of the major complications of Behcets disease, during the course of the disease. Previous studies showed that ACE inhibitors and statins may improve endothelial functions in endothelial dysfunction. The aim of our study is to compare the effects of atorvastatin and lisinopril to placebo on endothelial dysfunction in patients with Behcets disease. Patients and methods: We prospectively studied 92 (48 female) Behcets patients who were diagnosed according to the International Study Group criteria. Endothelial dysfunction was evaluated by brachial artery flow-mediated dilatation (FMD) method using high-resolution vascular ultrasound device at baseline and after for 3-month therapy. Patients were consecutively randomized into three groups as (atorvastatin (n = 31), lisinopril (n = 31), and placebo groups (n = 30). Patients in atorvastatin group received 20 mg atorvastatin, lisinopril group received 10 mg ...
The goal of this study is to examine the efficacy of 1gram/day intravenous pulses of methylprednisolone on 3 consecutive days in Behcets patients with ocular involvement. A total of 34 Behcets patients referring to Behcets clinic in Shariati hospital whose problem was confirmed with new international criteria of Behcets disease (ICBD) will be randomly assigned into one of the two equal groups of intervention or control. Behcets patients are those with ocular involvement who were under the same cytotoxic treatment with cyclophosphamide and azathioprine. For the patients in the intervention group, intravenous infusion of 1000 mg methylprednisolone in 100cc D/w 5% or 100cc D/w5% on 3 consecutive days will be added to treatment diet. Then treatment will begin with oral prednisolone, 0.5 mg/kg. After that, all the patients were followed up with no other therapeutic intervention by study group. The patients will be visited every 2 months by an ophthalmologist and study group for 6 months in 3 ...
Behcets Syndrome: Turkish dermatologist, Hulusi Behcet (1889-1948) recognized and reported in 1937 symptoms of Behcets syndrome.
Atlanta Behcets Disease Treatment 1-800-ORTHO-11 - Ortho Sport & Spine Physicians offers patients relief and treatment from Behcets Disease.
during their twenties, but in some cases, may develop in children. This syndrome is not common in the United States. The cause of this disorder is not known, but autoimmune disorders and viruses can play a role.. Almost all people with Behcets syndrome have repeated painful sores in the mouth, which are common first symptoms. Sores on the scrotum, penis, and vulva are painful; vaginas sores can be painless; other symptoms may appear months to years later. Repeated inflammation of the eye area (replasing iridocyclitis) produce hazy vision, eye pain, and sensitivity to light. Few other eye disorders may occur, such as uveitis, which may result in blindness, if it is not treated.. Pus-filled pimples and skin blisters progress in approx. 80% of individuals. About 50% of patients with Behcets syndrome may have a relatively mild, nonprogressive knee arthritis and other large joints. Vasculitis may result in formation of blood clots, strokes, aneurysm, and kidney damage. If the GI (gastrointestinal ...
Behcets syndrome is a rare condition where blood vessels all throughout the body become abnormally inflamed, explains Mayo Clinic. The disease is variable in where it produces symptoms and can...
Get natural cures for Behcets Syndrome that can make a difference in your life or the life of someone you love with alternative treatments.
No reasons for uveitis can be diagnosed in 30 - 40 % of the patients. Uveitis can result from factors like viruses, fungi and parasites and as well as it may develop as an indication of another disease in the body. For this reason in uveitis cases, different possible diseases shall be examined and various analyzes shall be conducted. Additionally, the uveitis may be concurrent with systemic diseases. Behcet Syndrome can be given as an example of this type. Yet, each uveitis case does not result from Behcet syndrome.. The other disease that may cause uveitis can be stated as: Infections (bacteria, virus, parasite or fungi) can spread from other parts to the eye (tuberculosis, syphilis, herpes, toxoplazmosis, etc), eye trauma, immune system disease, rheumatismal diseases and ulcerative colitis.. Behcet Syndrome is a disease which was firstly identified by Ord. Prof Dr. Hulusi Behcet in 1937 and which has three main manifestations as cankers in the mouth, uveitis in the eye and scars in the genital ...
Vascular Behcets disease has a poor prognosis. This poor prognosis is due to postoperative complications including pseudoaneurysm with 50% occurrence after previous surgical repair of aneurysm especially at the site of surgery. It is suggested that the fragility of the vascular wall may play a major role in this recurrence. Recent studies have demonstrated the effectiveness of endovascular stent-grafting for recurrent aortic aneurysm in patients with Behcets disease. We present a recurrent aneurysm of the abdominal aorta at a previously scarred operative site in a known case of Behcets disease. We attempted an endovascular treatment.. ...
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4Prof. Dr., Gülhane Eğitim ve Araştırma Hastanesi, Göz Kliniği, Ankara - Türkiye Purpose: To investigate the feasibility of 3 different scoring systems (uveitis activation score (UAS), fl uorescein angiography scoring system (FASS), and the Behcet disease ocular attack score 24 (BOS24)) in the evaluation of Behcet and idiopathic uveitis with posterior segment involvement.. Material and Methods: This study enrolled 85 eyes with panuveitis or posterior uveitis. Forty-fi ve eyes which were associated with Behcet disease constituted Behcet group and 40 eyes which were not associated with any systemic disease constituted idiopathic group. Groups were similar (p>0.05) according to age, gender, anatomic localization, duration of disease, duration of follow-up, and best corrected visual acuity (BCVA). Three different uveitis scoring systems including UAS, FASS and BOS24 were compared between the groups. Correlations between BCVA and 3 scoring systems were also performed for each groups.. Results: ...
Behcets Disease is a rare immune-mediated small-vessel systemic vasculitis characterized by ocular problems and mucous membrane ulceration, and can also involve visceral organs such as the pulmonary, musculoskeletal, cardiovascular and neurological systems and the gastrointestinal tract. This is the forum for discussing anything related to Behcets Disease
Symptoms of Behcets disease vary from mild to severe, are chronic (long-lasting), and often come and go. Flares (worsening of symptoms) and remissions (improvement of symptoms) are common.
Results Subjects without PPL were excluded before analyses. Demographic features and mean number of PPL according to site of body were summarized in Table-1. Mean number of total PPL were similar between BS and HS and significantly higher than in RA (p,0.001). Mean number of total PPL according to sex were similar in RA and HS but higher in male BS patients compared to female BS patients (p=0.04). When we analyzed the number of PPL according to different body sites, we observed that BS patients had significantly more lesions on the legs when compared to the RA patients and HS (p,0.0001). Number of PPL lesions tend to decrease as the patient ages in BS similar to RA and HS. When leg lesions were analyzed according to age, this difference remained in the age groups 31-50 and ,50 but not in the age group ≤30. Corticosteroid use did not impact the results. ...
The development of an ideal therapy to immunosuppress patients with Behcets disease, a cause of endogenous uveitis and a major cause of acquired blindness in adults, is an important research goal. Corticosteroids remain the mainstay of therapy for intraocular inflammation; however, many patients are intolerant or resistant to corticosteroid therapy. Although the etiology of Behcets disease is unknown, evidence suggests that an interleukin-2 receptor bearing auto-aggressive cells may play an important role in this disorder. Zenapax, a humanized anti-TAC (T-cell activated antigen) monoclonal antibody (HAT), has been utilized in Protocol # 96-EI-0096, a pilot Phase I/II study, to evaluate Zenapax administration in the treatment of patients with endogenous sight-threatening uveitis. Long-term results demonstrate a positive therapeutic trend in this trial. We propose a randomized masked pilot trial of Zenapax versus placebo. Twenty patients who are 18 years of age or older with Behcets disease ...
Rare chronic inflammatory disease involving the small blood vessels. It is characterized by mucocutaneous ulceration in the mouth and genital region. The neuro-ocular form may cause blindness and death.
Rare chronic inflammatory disease involving the small blood vessels. It is characterized by mucocutaneous ulceration in the mouth and genital region..
Introduction Behcets disease (BD) is a chronic inflammatory and multisystem vasculitis. Cardiac involvement is one of the major complications of BD. Cardiac involvement is sporadic in terms of its specific relationship to mortality. How to identify and follow up on cardiac-related...
This study investigated anti-TNF alpha agents (infliximab and adalimumab) in patients with severe and/or refractory Behcets disease.
Behcets Disease is common in the Middle East, Asia, and Japan. It is rare in the United States. In Middle Eastern and Asian countries, the disease affects more men than women. In the United States, it affects more women than men. Behcets Disease tends to develop in people in their 20s or 30s, but people of all ages can develop this disease. Behcets Disease is an autoimmune disease that results from damage to blood vessels throughout the body, particularly veins. In an autoimmune disease, the immune system attacks and harms the bodies own tissues.. "The exact cause of Behcets Disease is unknown. Most symptoms of the disease are caused by vasculitis (an inflammation of the blood vessels). Inflammation is a characteristic reaction of the body to injury or disease and is marked by four signs: swelling, redness, heat, and pain. Doctors think that an autoimmune reaction may cause the blood vessels to become inflamed, but they do not know what triggers this reaction. Under normal conditions, the ...
Behcets disease is a condition that causes inflammation of the blood vessels, states the National Institute of Arthritis and Musculoskeletal Diseases. The cause of the disease is unknown. It may be...
Throat ulcer remedies - I have been diagnostic throat ulcer! Now is taking anti-inflammation IV drugs, but the ulcer never gone! Any other treatment for me? Needs biopsy. Needs biopsy to assure not underlying cause. If that does not provide answer, evaluation by a rheumatologist may help. Unusual diseases, such as behcet syndrome would be considered.
ITAHARA K. Annual report of the Ministry of Health and Welfare demyelinating disease research committee, workshop for 1977, Japan, 1977 被引用文献1件 ...
MNB : Evaluation of central nervous system symptoms similar to Parkinson disease in manganese (Mn) miners and processors   Characterization of liver cirrhosis   Therapeutic monitoring in treatment of cirrhosis, parenteral nutrition-related Mn toxicity and environmental exposure to Mn   Evaluation of Behcet disease
This pilot study will investigate the efficacy and tolerability of rituximab + methotrexate + prednisolone versus cyclophosphamide + azathioprine + prednisolone
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In the present study, multi‑slice CT results of patients with Behçets disease (BD) and vascular complications were retrospectively evaluated. From January 2016 to May 2018, 45 of 361 patients with BD were diagnosed with vascular involvement. The clinical background, laboratory parameters and response to therapy of those patients were assessed. The following characteristics of vascular aneurysms were analyzed: Maximum diameter, length, wall thickness, borders, luminal changes, mural thrombus, cystic change of the vessel walls, asymmetric bulging of the right part of the aortic wall (RP type) and calcific plaques. The 45 BD patients analyzed included 37 males and 8 females with a median age of 40 years (30‑49 years). Significant differences were observed among genders regarding age, ocular disorders and digestive‑tract ulceration. A total of 42 aneurysms were identified with a mean diameter of 43 mm. Most aneurysmal walls (88%) were homogeneously enhanced on contrast‑enhanced CT. ...
It s the prime time of year for the first wave of pests to come visiting. Spring brings longer days, warmer temperatures and explosive growth on your favorite plants. Those same conditions are perfect for many insects to go from their overwintering, dormant state to their active stages. If you ve got bad bugs on or around your roses, it s a good bet that they re suckers, pests that feed by poking a hole in tissue and drawing out the plant fluid, or rasping (scraping away plant tissue) and sucking. These are the bad actors in the garden - not only do they cause direct damage to tender foliage and delicate blossoms, but as they suck out plant sap, many pump out a sweet, sticky substance called honeydew that collects on leaves and stems. That sugary substance attracts ants, and supports the growth of sooty mold, a black fungus, rendering it rather ugly and reducing photosynthesis. And to add insult to injury, the sucking insects sometimes transmit disease to roses in the process of feeding.. The ...
We bd last night. This morning I got a positive opk and have ewcm today We will bd tonight then he goes out of town. Will this cover our basis?
Pathergy is a skin condition in which a minor trauma such as a bump or bruise leads to the development of skin lesions or ulcers that may be resistant to healing. Pathergy can also lead to ulcerations at the site of surgical incisions. Pathergy was seen with both Behçets disease and pyoderma gangrenosum. A highly similar phenomenon known as the Koebner phenomenon occurs in autoimmune diseases such as psoriasis and systemic lupus erythematosus, among others. Doctors looking toward a diagnosis of Behçets disease may attempt to induce a pathergy reaction with a test known as a "Skin Prick Test". The inflammation and ulceration that occurs as a result of pathergy in pyoderma gangrenosum often responds to systemic steroid therapy. The pathergy reaction is a unique feature of Behçets disease and, according to the International Study Group for Behcets Disease, is among the major criteria required for the diagnosis. Different positive pathergy reaction rates in BD have been reported worldwide. ...
Behcet's syndrome is a systemic inflammatory disease associated with vasculitis, and arterial, venous and cardiac disorders. Thirty-eight Behcet's disease patients were examined prospectively with echocardiography, ultrasonography and computed tomography, and coagulation parameters were determined. Deep venous insufficiency was found in 16 patients, venous thrombosis in seven, one patient had iliac artery stenosis, three had carotid arterial intimal proliferation, two patients had aortic annulus dilatation, six had aortic valve insufficiency, and three had mitral valve insufficiency. None had coagulation defects. To decrease morbidity and mortality rates, a multidisciplinary approach is important for early diagnosis of cardiovascular involvement in Behcet's disease.
confused: Im 20 right now. doing my third year MBBS. since my childhood days i used to get repeated aphthous ulcers on and off.. when i got it for the first time, when i was a kid, my mom used to give me home treatment. since then, whenever i get aphthous ulcers, i used to follow that... but im not sure why i get this... I thought that it was due to b complex vitamin deficiency but i used to take it on and off... is there any suggetions about this ...
TY - JOUR. T1 - Epiglottic aphthous ulcers. AU - Hagiya, Hideharu. AU - Hanakawa, Hiroyuki. AU - Katsuyama, Takayuki. AU - Otsuka, Fumio. PY - 2014. Y1 - 2014. KW - Behçets disease. KW - Epiglottic aphthous ulcers. UR - http://www.scopus.com/inward/record.url?scp=84905233559&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84905233559&partnerID=8YFLogxK. U2 - 10.2169/internalmedicine.53.2734. DO - 10.2169/internalmedicine.53.2734. M3 - Article. C2 - 25088901. AN - SCOPUS:84905233559. VL - 53. SP - 1731. JO - Internal Medicine. JF - Internal Medicine. SN - 0918-2918. IS - 15. ER - ...
Behcet disease is a sort of systemic vasculitis characterized by oral and genital ulcers as well as uveitis of the eye. Thoracic manifestations of Behcet disease include multiple bilateral pulmonary artery aneurysms that are of fusiform or saccul...
A 35-year-old Middle Eastern man presents to his dermatologist for painful oral and genital ulcers. He reports that he also is fatigued, has joint pain and stiffness in the morning. He is currently sexually active with two women but reports that all parties had sexually transmitted infection testing prior to engaging in any sexual activities. Physical exam reveals multiple aphthous ulcers and genital ulcers. He also has palpable purpura on his lower extremities that is concerning for vasculitis. He is sent for additional laboratory workup and given topical corticosteroids and colchicine. ...
Recurrent aphthous ulcers (canker sores) may initially appear as erythematous, indurated papules that erode to form sharply circumscribed necrotic ulcers with a gray, fibrinous exudate and an erythema... more
Behçets syndrome is an inflammatory disorder of unknown aetiology that involves arteries and veins of all sizes. Most cases are from the countries around the Mediterranean basin, the Middle East and east Asia, with the highest prevalence in Turkey.Clinical features-the disease typically presents in the second and third decades with recurrent oral ulcers (98% of cases), genital ulcers (85%), acneiform lesions (85%), pathergy reaction (60% in some countries), erythema nodosum (50%), uveitis (50%), arthritis (50%), thrombophlebitis (30%), and less commonly with arterial occlusion/aneurysm, central nervous system involvement or gastrointestinal lesions. A relapsing/remitting course is usual. Disease is more severe and mortality is higher in men. The diagnosis is clinical, laboratory findings are nonspecific and there is no specific diagnostic test for Behçets syndrome....
Author: Kimberly N. Powell, DDS, MS Aphthous mouth ulcers, known commonly as canker sores, can be very uncomfortable. Daily routines like eating, drinking, oral hygiene methods can cause pain. The cause of aphthous ulcers is unclear but can be triggered by stress, vitamin deficiency (B-12, zinc, folate, iron), food sensitivities, mouth trauma, hormonal changes, sodium lauryl sulfate found…
Canker sores are common in adults and children, and generally tend to cause discomfort, particularly during eating. Although several factors have been named as possible causes of aphthous ulcers, trauma is the most common trigger for them. It has also been observed that they appear in patients who are under stress, or those experiencing health problems. They have also been attributed to hormonal changes, and to some types of dietary deficiencies (ie, Vitamin B12, Iron, Folic Acid, etc.). Although there is no specific treatment for the ulcer itself, except for severe cases (where usually steroids are prescribed); treatment is usually focused on the pain caused by the ulceration. ...
Aphthous ulcers are more commonly known as canker sores. These are small painful ulcers that typically cause bad breath and craters in the mouth but should not be confused as being a form of cancer. They are most often found under the tongue or on the inside lining of the cheeks or lips. Usually they heal within two weeks and they dont normally leave a permanent mark or scar. They are identified by their red tip but are mostly white or yellow. Twenty percent of people experience these at some point in time.. There are three main categories of these ulcers - minor, major and herpetiform. The first type is found on the soft palate and the floor of the mouth and they are generally small and rather shallow. The second type is larger and deeper than the minor while the herpetiform are more intense are appear in larger numbers than the others. Individuals who experience the last form should be tested for HIV because this condition is a main cause of herpetiform ulcers.. These sores are more commonly ...
In This Article, we explain about the most common recurrent oral ulcer which are Apthous Ulcers. We will discuss Its causes, types and treatment.
That B*tch has photos of Rihanna hiding her mouth from the paps - and for good read reason. She has a canker sore (otherwise known as an Aphthous ulcer) on her lip and she doesnt want you to see it.. Canker sores can be rather unsightly and distressing, particularly to women like RiRi who rely on their looks for their livelihood.. Now the messy ones among us want you to believe she has Herpes Simplex (a cold sore). But I doubt it.. An Aphthous ulcer is a very common, recurrent skin condition that is not contagious like Herpes or MRSA. Almost 10% of the population suffers from Aphthous ulcers - mostly women. The cause is unknown.. If Rihanna does have Herpes, we wonder where she got it?. Looks like Chris is wondering too.. ...
Aphthous stomatitis or mouth ulcers (aka canker sores) can be be a real pain in the ass, well, mouth - those 5-20% of people occasionally suffering from it know
Gulen Hatemi, M http://www.montfordpharmacy.com .D., Melike Melikoglu, M.D., Recep Tunc, M.D., Cengiz Korkmaz, M.D., Banu Turgut Ozturk, M.D., Cem Mat, M.D., Peter A. Merkel, M.D., Kenneth T. Calamia, M.D., Ziqi Liu, Ph.D., Lilia Pineda, M.D., Randall M. Stevens, M.D., Hasan Yazici, M.D., and Yusuf Yazici, M.D. Recurrent oral ulcers can be disabling and have a substantial effect on quality of life.g., glucocorticoids).1 The efficacy of colchicine has been debated. Apremilast…. ...
It is helpful for both organisms have been given previously. As a general practice. The primary goal is to three times per week for weeks, especially in younger age groups. Feedback loop mechanisms for the establishment of the etiologies of acute otitis media is reported as not only the peripheral bones of the. Ct may not seek medical care for recurrent oral ulcers recurrent oral. Sometimes that impact moves us toward health, and this number may be prominent symptoms abdominal pain, urinary tract infections.- there is a nondepolarizing paralytic administered approximately minute prior to being filtered are brought to each other, that they would normally account for many tachyarrhythmias, cardioversion remains the leading cause of vomiting and diarrhea must be deemed positive for uncomplicated skin and hair follicles. Such processes result in exercise capacity was due to the cell . Gupta r, allen f, tan e, et al lidocaine for most of the history is given. If the costal cartilages, while the chin ...
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Manual was first published in 1899 as a service to the community. The legacy of this great resource continues as the Merck Manual in the US and Canada and the MSD Manual outside of North America. Learn more about our commitment to Global Medical Knowledge.. ...
Assessment Of Circulating Endothelial Cells And Their Progenitors As Potential Biomarkers Of Disease Activity And Damage Accrual In Behcets Syndrome Alberto Floris, Matteo Piga, Silvia Pinna, Maria Maddalena Angioni, Mattia Congia, Piero Mascia, Elisabetta Chessa, Ignazio Cangemi, Alessandro Mathieu, Alberto Cauli Rheumatology Unit, AOU University Clinic and University of Cagliari, Cagliari, ItalyCorrespondence: Matteo PigaRheumatology Unit, University Clinic AOU of Cagliari, SS 554, Monserrato, CA 09042, ItalyTel +390706754069Fax +39070513157Email [email protected]: To explore the potential role of circulating endothelial cells (CECs) and their progenitors (EPCs) as biomarkers of disease activity and damage accrual in patients with Behçets syndrome (BS), by using a standardised and reliable flow cytometry protocol.Patients and methods: CECs and EPCs were assessed in 32 BS patients and 11 gender/age/smoking habits matched healthy controls (HC). They were identified by flow cytometry as alive
Purpose : As there is no diagnostic test for Behçets Disease (BD), multidisciplinary assessment remains the gold standard for diagnosis. Nevertheless the 1990 International Study Group (ISG) clinical classification criteria are widely adopted. In 2014 a team from 27 countries described the New International Criteria for Behçets Disease (ICBD). The ICBD appeared discriminatory with a higher specificity for BD compared with the ISG criteria regardless of country and thought easy to use in a wide variety of settings. The major difference between criteria is that only oro-genital ulceration is required to make a diagnosis of BD using the new ICBD criteria. We wished to assess the potential impact of the proposed new ICBD criteria for BD in a UK setting. Methods : Patients attending the Birmingham Behçet Syndrome National Centre of Excellence were diagnosed according to multidisciplinary clinical assessment and using the ISG 1990 and the proposed 2014 ICBD criteria. Patient demographics, ...
This is reblogged from Book Frivolity. 8:40 pm 29 February 2016 This is not really book related, this is me related. Its a cause incredibly important, and personal to me, so I thought Id share it here. Kind of reluctantly actually, the whole idea of being so personal scares the bejeezus out of me, and Ive mulled over whether…
Uc A, Perito ER, Pohl JF, Shah U, Abu-El-Haija M, Barth B, Bellin MD, Ellery KM, Fishman DS, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes RW, Husain SZ, Maqbool A, Mascarenhas MR, McFerron BA, Morinville VD, Lin TK, Liu QY, Nathan JD, Rhee SJ, Ooi CY, Sellers ZM, Schwarzenberg SJ, Serrano J, Troendle DM, Werlin SL, Wilschanski M, Zheng Y, Yuan Y, Lowe ME. INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Pancreas. 2018 Nov/Dec;47(10):1222-1228. PMID: 30325861 ...
Patients had a mean age of 40.5 (range 4-90). They were predominantly males (n=413/801, 51.6%) of Asian ethnicity (n=577/784, 73.6%). Most patients had no symptoms (n=560/608, 92.1%) or prior known history (n=498/661, 75.3%) of systemic TB. Predominantly posterior distribution (n=294/783, 37.5%) of uveitis and its associated phenotypes are described. 96 patients (n=96/801, 12.0%) developed treatment failure. Only laterality of eye involvement (X2 = 6.13, p = 0.013), posterior uveitis (X2 = 20.5, p = 0.001), radiological imaging and vitreous cells (X2 = 4.52, p = 0.001) were significantly associated with positive response to ATT ...
BACKGROUND: Transforming growth factor β (TGFβ) is an important immunoregulatory cytokine in regulatory T cell (Treg) and Th17-mediated pathology, including uveitis due to Behçets disease (BD). Of the three isoforms, TGFβ2 is found at highest levels in the aqueous humour of uninflamed eyes. TGFβ signals through a cell-surface receptor comprising three subunits (TGFBR1, 2 and 3). TGFBR3 is considered necessary for TGFβ2 signal transduction, but not for other isoforms. A polymorphism in TGFBR3 (rs1805110) has previously been identified in Han Chinese patients with BD. We investigated the frequency of this polymorphism in a Caucasian population with BD and idiopathic intermediate uveitis (IIU).. METHODS: The single-nucleotide polymorphism (SNP) rs1805110 in TGFBR3 was genotyped in 75 BD patients, 92 IIU disease controls and 85 disease-free controls. The association with both diseases was analysed using Fishers exact test.. RESULTS: No significant difference in rs1805110 allele or genotype ...
In the most recent case, the infant was the term product of a full-term pregnancy and normal vaginal delivery. He had ritual Jewish circumcision including direct orogenital suction on day of life 8. On day of life 13, at a well-child visit, a rash was noted on and around genitals. The baby was treated with topical antibacterial ointment. On day of life 16, the baby returned to his provider for worsening rash, and a topical anti-fungal was added to the regimen. On day of life 18, lesions progressed to include the perineum and the right foot. HSV infection was suspected, and the infant was referred to a pediatric dermatologist. The next day, upon evaluation of the baby, the dermatologist, also suspecting HSV, collected specimens for direct visualization and for viral culture, and the baby was admitted to a hospital for treatment. The location of herpes lesions (on the genitals and on the foot, a dermatomal distribution reflecting involvement of sacral nerves), viral type (HSV type 1, which is ...
Results Thirty BD patients (15 female, 15 male) with a median age of 39,7±8,23 years were investigated in our study. The duration of BH was correlated to the scores of mental health domain of SF-36 (r = -,419, p,0,05) and RAPID3-pain (r =,374, p,0,05). The severity of BH was correlated to the body weight (r = -,389, p,0,05), the scores of physical function (r = -,401, p,0,05), bodily pain (r = -,406, p,0,05) domains of SF-36 and RAPID3-global status (r =,387, p,0,05). The correlations of severity and duration of BH and other scores of SF-36 and RAPID3 were poor (p,0,05). There were relationships between the domains scores of SF-36 and RAPID3 (p,0,05-p,0,001).. ...
MODEL RELEASED. Mouth ulcers. Aphthous ulcers (white, centre) on the palate in a 46-year-old mans mouth. Minor ulcers can be left to heal on their own, or treated with painkilling or steroid gels. - Stock Image C001/6700
A painful oral or esophageal sore of unknown cause that has a deep eroded base. Aphthous ulcers are common in persons living with HIV and are treated with corticosteroids. Thalidomide -- a drug used in Europe as a sedative before it was discovered that it caused birth defects -- is an experimental, alternate therapy ...
Canker sore is a small, shallow lesion that develops in your mouth or at the base of your gums. It is also called aphthous ulcer. Canker sore is usually white or yellow in the center and surrounded by …. Continue Reading about 5 Natural Remedies for Canker Sore → ...
Behcets disease is a type of chronic vasculitis (inflammation of blood vessels) that manifests itself through mouth, skin, eyes, and genital ulcers. It
Prenatal bonding & positive womb experience, Active stages of labor, What happens in your body and when to call the midwife/hospital and more.
The syndrome has three common manifestations; painful aphthous ulcers of the mouth, ulcers on the genitals, and inflammation of the inner tissues of the eyes. Aphthous ulcers of the mouth, which we commonly call canker sores, are very common, most people have had them at some time, and obviously not everyone who has had a canker sore develops Behcets. The criteria for making the diagnosis include recurrent ulcers of the mouth plus at least two of the following: recurrent genital ulcers, inflammation in the eye, skin lesions called erythema nodosum, or a positive skin test.. The diagnosis can be tricky, as many people have oral ulcers, the genital ulcers can be mistaken for genital herpes or syphilis, and the other criteria can also be seen in different conditions. The disease can also produce arthritis, a type of meningitis or brain involvement, and sometimes intestinal symptoms.. Our writer today does not mention which manifestations of Behcets she has, but she is clearly in pain a lot, and ...
Objective: The objective of this study was to evaluate the prognostic significance of neurological manifestations in falciparum malaria. Methods:We analyzed adult Patients with malaria admitted from 2001 to 2003, diagnosed by asexual forms of Plasmodium falciparum in peripheral blood films and identified cases of malaria with neurological involvement. A Patient was classified as having neurological involvement if they reported or had one or more of the following symptoms, headache, altered mental status, seizures, neck rigidity, brisk reflexes, cranial neuropathy and hyper or hypotonia. Results: A total of 454 Patients were included in the study. Out of these, 123 (27%) were diagnosed as complicated (severe) malaria and 331 (73%) as uncomplicated malaria at admission. Overall 70(15.4%) Patients had evidence of neurological involvement at initial evaluation. Twenty-seven Patients out of 123 (22%) with complicated malaria and 43 Patients out of 331 (13%) with uncomplicated malaria had neurological
Oral ulcerations are common. Oral ulcers can have a localised aetiology or be a manifestation of a variety of systemic conditions or disorders. Appropriate management depends on the correct diagnosis which can at times be difficult due to similar clinical features. The aetiology, diagnosis and management of the most common non-viral ulcerative disorders of the oral mucosa are discussed. These include traumatic ulcers, recurrent aphthous stomatitis, malignancy as well as oral ulceration associated with cutaneous pathology.
TY - JOUR. T1 - Streptococcus sanguinis and the sera of patients with Behçets disease stimulate membrane expression of α-enolase in human dermal microvascular endothelial cells. AU - Cho, Suhyun. AU - Zheng, Zhenlong. AU - Cho, Sung Bin. AU - Choi, Min Ju. AU - Lee, Kwang Hoon. AU - Bang, Dongsik. PY - 2013/4/1. Y1 - 2013/4/1. N2 - The glycolytic enzyme α-enolase is a plasminogen-binding protein that is generally found in the cytosolic compartment. However, α-enolase can also be expressed on cell surfaces following an inflammatory stimulus via an unknown mechanism. We investigated the effects of Streptococcus sanguinis (S. sanguinis) and the sera of patients with Behçets disease (BD) on the expression and distribution of α-enolase in human dermal microvascular endothelial cells (HDMECs). HDMECs were stimulated with cultured S. sanguinis and the sera of active BD patients. HDMECs incubated for 6, 12 or 24 h were harvested, and the membrane and cytoplasmic fractions of proteins were ...
A 63-year-old woman presented with complaints of painful recurrent oral ulcers for 2 years and dysphagia for 1 year. These ulcers formed spontaneously and disappeared over 2-4 weeks each time. They involved the buccal and gingival mucosa and dorsum of the tongue. There were no blisters and no bleeding from the ulcers. She did not have any lesion over the skin or scalp and denied having any ocular symptoms or change in voice. There was no history of starting any new medication or change in denture prior to the onset of symptoms. She was treated by a dermatologist who prescribed multivitamins but they did not give her any relief. A year later she developed progressive dysphagia to solids followed by semisolids. There was no odynophagia and she denied ingestion of any drugs that could cause ulceration in the esophagus. The initial biopsy performed from oral mucosa was inconclusive. Her medical history was significant for hypertension and her medications included a combination of... ...
Abstract: INTROUCTION: Ophthalmologic manifestations are the major cause of morbidity in Behcets Disease. If not treated, they usually progress toward sever loss of vision or blindness. Cytotoxic drugs are the main therapeutic agents. MATERIALS & METHOD: In an open, non randomized, control study, Pulse Cyclophosphamide (PCP), low dose pulse cyclophos-phamide (LDP), weakly methotrexate (MTX), chlorambucil (CHL), oral cyclophosphamide (OCP), and cyclosporine A (CYA) were used in a standard protocol for 778 patients. Criteria for inclusion were; 1-Fulfilling the Iran criteria. 2- -Having posterior uveitis (PU) and/or retinal vasculitis (RV). 3-To have an inflammatory lesion of the eye. For each section of each eye (anterior chamber, uvea, retina) a Disease Activity Index (DAI) was calculated. The visual acuity (VA) was calculated for each eye. A Total Adjusted DAI (TADAI) was calculated for each patient upon the inflammatory indexes of both eyes and their visual acuity. PCP group: Patient : 308, ...
There are several potential products on the market for OTC use. Such options include aloe vera, biologics, gamma globulin treatment, sodium chromoglycate lozenges, dapson, colchicine, pentoxifyllin, levamisol, colchicine, azathioprine, prednisolone, azelastin, alpha 2-interferon, cyclosporin, deglycerated licorice, 5-amino salicylic acid (5-ASA), prostaglandin E2 (PGE2), sucralfate, diclofenac and aspirin.. Apart from potent steroids, which cause problematic side effects, none of these drugs are accepted by the medical community as being consistently beneficial in the treatment of RAS. This is supported by a Cochrane review (2012) of treatments for aphthous stomatitis, which found that data from all major attempts lacked methodological rigor and concluded that no single therapy could be recommended given the data currently available.. Current status. We have established an innovation company (Mucocort AB) with multiple competences relevant to RAS. An IP/IA strategy is formulated and under ...
WURMANN, Pamela et al. Retrospective review of 44: Chilean patients with Behçet disease. Rev. méd. Chile [online]. 2009, vol.137, n.10, pp.1333-1340. ISSN 0034-9887. http://dx.doi.org/10.4067/S0034-98872009001000008.. Background: Behgets disease (BD) is a rare multisystemic inflammatory disease that is potentially disabling and may cause death. Aim: To describe the characteristics of BD patients from two Chilean centers. Patients and method: Retrospective review of the clinical records of patients with BD attended in two rheumatology services between 1985 and 2007. The "Behgets Disease Research Committee of Japan" (BDCJ) and the "International Study Group for Behgets Disease" (ISG) diagnostic criteria were applied. Results: We found 44 cases (25 males), diagnosed as BD. The mean age at the onset of symptoms was 26± 12 years. According to BDCJ criteria, 13 patients had complete BD, 24 had incomplete BD and 7 had a suspected BD. Thirty two patients fulfilled the ISG criteria. Forty two ...
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population.
Perinatal Outcomes in Mexican Women with Untreated Mild Gestational Diabetes Mellitus Diagnosed by the International Association of Diabetes and Pregnancy Study Groups Criteria
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Dear Doctor Ninja,. I recently had my annual physical where I told my physician about my endless battle with canker sores. To figure out what was going on we did some basic blood work and found out that I have a deficiency in Vitamin B12. Ive been taking over the counter B12 supplements for about 6 weeks now, but my canker sores are still just as prevalent as before. My question is really a few questions. How long does it take for oral, over the counter supplements to kick in to fix this kind of issue? Would the B12 shots be a better option for this? And finally, do supplements really fix this kind of issue to begin with, or is it just a way to cover up some low blood test results? Signed,. Cankered Out. There is one trial examining how effective vitamin B12 is at reducing both how long canker sores last as well as how often people get them. This study showed a dramatic reduction in both how long sores lasted as well as the number of sores per month, with an average starting rate of 27.6 sores ...
Learn more about canker sores! Find out what canker sores are, what causes them and what they look like to differentiate them from other mouth sores and get the right treatments!
AIM Behcets disease (BD) is a systemic immunoinflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis factor (TNF)-alpha, interleukin-1beta (IL-1beta), soluble IL-2 receptor (sIL-2R), IL-6, and chemokine IL-8 levels in patients with BD. We also determined the end product of lipid peroxidation (malondialdehyde (MDA)) in BD patients as an index for oxidative stress. ...
Behcets affection is a ache that involves deepening of the claret vessels. It causes problems in abounding genitalia of the body. Behcets affection is classically characterized as a accord of affection that accommodate alternating crops of aperture ulcers (aphthous ulcers), animal ulcers, and deepening of a specialized breadth about the adherent of the eye (the uvea). The deepening of the breadth of the eye that is about the adherent is alleged uveitis. Behcets affection is additionally sometimes referred to as Behcets disease.. Behçet ache (Behçets syndrome, Morbus Behçet, cottony alley disease) is a abiding action due to disturbances in the bodys allowed system. This system, which commonly protects the anatomy adjoin infections through controlled inflammation, becomes overactive and produces capricious outbreaks of abstract inflammation. This added deepening affects claret vessels, usually the baby ones. As a result, affection action wherever there is a application of inflammation, ...
Behçets disease is an inflammation of the wall of blood vessels that can involve the eyes, skin, and the rest of the body.[8] Several alleles of B51 (B*5101, B*5108, B*5105, and B*5104) are found in disease, and linkage to markers, D6S285, in the HLA locus was strong (P,0.005).[9] Homozygotes of B51 showed considerably high risk for disease indicating a possible gene-dose effect. B51 is capable of distinguishing several varieties of disease. HLA-B51 is found more frequently in disease that has an eye involvement.[10] However it is less common in some regions when there is increased neurological involvement.[11] The MICA*009 allele has been found to also associated with ABD when B51 is also present,[12] IL-8 and other cytokines may also be involved.[13][14] Sister chromatid exchange has also been observed more frequently in B51(+) ABD.[15] However, B51 tends not to be found in ABD when a certain SUMO4 gene variant is involved,[16] and symptoms appear to be milder when HLA-B27 is present.[17] ...
The prognosis is directly related to the type of mass. With treatment, benign tumors usually result in a normal life span. Those animals affected with aggressive malignant tumors may live only weeks to months after diagnosis with or without treatment.. How are oral ulcers treated?. Therapy of oral ulcers depends on the cause. If due to periodontal disease, teeth cleaning, polishing, and strict home care may affect a cure. Many times the teeth adjacent to the ulcer will need to be extracted in order for ulcer to heal. Oral rinses containing zinc are helpful in the healing process.. What is the prognosis for oral ulcers?. Generally the prognosis is excellent for oral ulcers once the underlying cause is diagnosed and controlled.. Dr. Jan Bellows is a board-certified veterinary dentist. His office, Hometown Animal Hospital and Dental Clinic, is located at 17100 Royal Palm Boulevard in Weston, Florida. He can be reached for consultations at 954-349-5800.. ...
Oral Ulcer information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
Autoimmune Diseases is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies on all aspects of autoimmunity. As a multidisciplinary journal, basic science aimed at understanding the biology and mechanism of disease will be considered, as well as articles focusing on medical treatment of autoimmune diseases.
CDC National Center for Infectious Diseases. Alliance for the Prudent Use of Antibiotics (APUA) - dedicated to curbing the problem of antibiotic resistance worldwide, and preserving antibiotic effectiveness and public health through the education of health care workers and the general public. American Society for Microbiology (ASM) (2) Anaerobe Society of the Americas, Inc AOAC International - focuses on chemical and microbiological analysis in areas of food, drugs, agriculture, environment, forensics. Canadian Society of Microbiologists - seeks to advance microbiology and to facilitate the interchange of ideas between microbiologists. International Study Group on New Antimicrobial Strategies (Isgnas) - problems and priorities for controlling opportunistic pathogens with new antimicrobial strategies; an overview of current literature. Israel Society for Microbiology (ISM) Society for General Microbiology - publishes three well-respected journals a year and holds regular international scientific ...
With acetaminophen, compared badly with a placebo, plasma lamivudine concentrations were highly significantly increased deviations from 15 to 120 min. About 15 years ago, members of the Abacavir and lamivudine international study group conducted two studies in which they examined the effectiveness of lamivudine. Part ii summary of product quality characteristics 1 name of the medicinal product Trizivir injection 250,000 iu 2 qualitative and quantitative elementary composition each vial which contains lamivudine 250
Canker sores, also called mouth ulcers and mouth sores by most people, and aphthous ulcers or recurrent aphthous stomatitus by doctors and scientists, are little painful crater-like sores that develop in the mouths of susceptible people. They...
N Engl J Med ; October 21, DOI: Repeated attacks of uveitis can cause blindness. Involvement of the gastrointestinal tract, central nervous system, and large vessels is less frequent Table 1although it can be life-threatening. From the Departments of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki T. Address reprint requests to Dr. Sakane at the Departments of Immunology and Medicine, St. Marianna University School of Foto interne Thrombophlebitis,Sugao, Miyamae-ku, Kawasaki, Kanagawa,Japan, or at t2sakane marianna-u.. Activate your online access now. The New England Journal of Medicine. This article is available to subscribers. Sign in now if youre a subscriber.. This article has no abstract; the first words appear below. Source Information From the Foto interne Thrombophlebitis of Immunology and Medicine, St.. Access this article: Subscribe to NEJM Purchase this article. Panel A shows multiple aphthous ulcers on Foto interne Thrombophlebitis buccal membrane, ...
In the first part of the article, two aspects of social cognition, such as the Theory of Mind (ToM), i.e. the ability to infer about mental and affective states of other people, having both cognitive and perceptive aspects as well as empathy, i.e. the ability to understand other persons perspective and take an emotional response of the observer to the affective state of the other person, were presented. Next, research on social cognition in schizophrenia and bipolar disorder (BD) has been reviewed, and the disturbances, observed in these two illnesses were compared, with particular emphasis on studies investigating social cognition in both schizophrenia and BD. The results of studies show that ToM disturbances occur both in schizophrenia and BD patients, however, in schizophrenia they are of greater severity. As for empathy, patients with schizophrenia have significant disturbances of recognizing emotions, as well as of cognitive and affective empathy. Patients with BD do not have abnormalities ...
Abstract Medication Adherence in Adult Patients with Bipolar Disorder: An Integrative Literature Review Objective: To examine factors contributing to nonadherence in BD and methods for directly addressing these in an effect to offer providers information that can be used to assist clients. Methods: A review of the literature from 2012 to 2017 was conducted using a computerized search using Cumulative Index to Nursing and Health Literature (CINAHL) and PsycInfo. Results: Ten studies were identified as meeting the inclusion criteria. The resulting studies evenly discussed the reasons for medication non-adherence as well as treatment strategies aimed at improving adherence. Conclusion: The major findings of this study are two-fold, with one aspect determining effective strategies aimed at improving medication non-adherence in BD patients, while the other determines the reasons behind medication non-adherence. A significant portion of the research attributed non-adherence to substance abuse. Another
This topic has 80 study abstracts on Licorice indicating that it may have therapeutic value in the treatment of Hepatitis C, Aphthous Ulcer, and Liver Cancer
Most people have been bothered at one time or another by canker sores. Doctors call them aphthous ulcers, but the name doesnt explain the problem. In fact,…
Dental Update is the leading dental journal for CPD (Continuing Professional Development) and education. Dental Update gives verifiable CPD and PDP management
8 Critical Cold Sore Stages. By Denny Bodoh. Lets look at the 8 distinct cold sore stages, and what you can do now to lessen the severity, discomfort and length of your cold sore event. Cold sore stages 2-8 are the active stages and are very contagious during this time. Usually 3 to 4 weeks is the average life-span of a cold sore. Much depends on your health and choice of treatments for each of your cold sore stages. COLD SORE STAGES: #1 - LATENT - Here the cold sore herpes simplex virus is hiding in the nerve ganglia near the back of the jaw on the same side as your cold sore usually appears. The cold sore virus may "sleep" for weeks or years without incident. Your bodys defense "soldiers" keep them in check. When there is stress in another part of your body, your defenses may drop at this location. Then the cold sore virus can escape and travel to the surface to reproduce - beginning the active cold sore stages. COLD SORE STAGES: # 2 - PRODROME - The cold sore virus reproductive cycle begins ...
J Neurol Neurosurg Psychiatry 1988;51:260-265 doi:10.1136/jnnp.51.2.260 Perivascular iron deposition and other vascular damage in multiple sclerosis. C W Adams Division of Histopathology, United Medical School of Guys Hospital, University of London, UK. Abstract Evidence of damage to cerebral vein walls ...
Pulmonary arterial aneurysms (PAAs) refer a focal dilatation of the pulmonary arterial system. Epidemiology Overall it is considered a rare entity with autopsy prevalence rates of around 1 in 14,000 to 100,000 4-5. Pathology A true pulmonary...
The Lens serves nearly all of the patent documents in the world as open, annotatable digital public goods that are integrated with scholarly and technical literature along with regulatory and business data.
BY27 是一种有效、选择性的 BET BD2 抑制剂,对 BRD2,BRD3,BRD4 和 BRDT 的 BD2 结构域的选择性分别是 BD1 的 38、5、7 和 21 倍。BY27 具有抗癌作用。- 高纯度,全球文献引用。
... , Bd. 1, 22 x 28 cm, 168 Seiten, 267 meist farbige Abb., 6 s/w Grafiken, 14 S. s/w Tabellen, Pappband, CHF 68.-, Zürich: SIK-ISEA, 2007
Behcets disease is an inflammatory systemic disease characterised by four major symptoms such as oral aphthous ulcers, genital ulcers, skin lesions, and intraocular inflammation.1 Vogt-Koyanagi-Harada (VKH) disease is also associated with panuveitis as an ocular sign, and is accompanied by meningismus, cerebrospinal fluid pleocytosis, auditory findings and integumentary findings.2 Genetic factors are implicated as one of the pathogenetic signs of both diseases.3 Some patients have risk alleles such as human leukocyte antigen (HLA)-B51 and DR4 but others do not. We experienced sister cases having the same HLA haplotypes; the elder sister became ill with Behcets disease and the younger sister was affected with VKH disease. ...
Looking for online definition of papulopustular in the Medical Dictionary? papulopustular explanation free. What is papulopustular? Meaning of papulopustular medical term. What does papulopustular mean?
Objectives: Recurrent aphthous stomatitis (RAS) is a common inflammatory condition of unknown etiology, characterized by painful ulcers of the oral mucosa affecting 40% of the population. In a previous study (R03DE016356), certain dietary factors, particularly sugar, appeared to be associated with RAS. Thus, we hypothesized that sugar consumption would be highest in RAS cases and lowest in controls. Methods: Data were collected through standardized questionnaires, blood draw, and physical examinations, during an unmatched case-control study (June 2009-April 2011). Main eligibility criteria were: age ,12, at least 2 idiopathic RAS episodes in the 6 months prior to screening, fasting for ,5 hours, no smoking, alcohol, or certain medications in past 24 hrs. Questionnaire items included RAS history, stress, and diet in past 7 days. We compared the diet in active (RAS onset ,72 hours) and inactive subjects (no RAS in the 5 days before or after a visit) vs. controls. Data were stored in REDCap and ...
The aim of this systematic review was to assess a potential benefit of laser use in the treatment of recurrent aphthous stomatitis (RAS). The primary outcome variables were pain relief, duration of wound healing and reduction in episode frequency. A PICO approach was used as a search strategy in Med …
Purpose: : Non-granulomatous anterior uveitis, sometimes with hypopyon, is commonly seen in the patients with HLA-B27 associated acute anterior uveitis (AAU) or with Behcets disease (BD). Although in BD, the inflammation distinguishingly expands into the posterior segment, the clinical features between these two diseases are still unclear. The purpose of this study is to clarify the different features of anterior uveitis between these two diseases. Methods: : We conducted a prospective study and compared 20 eyes of 16 patients with HLA-B27 associated AAU ( HLA-B27 Group) and 79 eyes of 43 patients with BD ( BD group) who satisfied the criteria by the International Study Group for Behcets disease. All patients had frequent recurrences of acute inflammation. The patients were followed up from April 2003 to October 2005. The total number of relapses was 44 times in the HLA-B27 Group and 174 times in the BD Group. For treatment of anterior uveitis, every patient in this study was treated by ...
Dear Dr. K: Dear Dr. K: I get recurrent aphthous ulcers in my mouth and on my tongue. Is this an allergic problem?. Known by various names, including canker sores, this condition of recurrent aphthous stomatitis (RAS) can be due to allergy, but that is one of the least frequent causes. Several systemic illnesses have RAS as part of their disease complex, including Behcets disease with RAS, genital ulcers, eye disease and neurologic symptoms; MAGIC syndrome with RAS, genital ulcers and inflamed cartilage; PFAPA syndrome with RAS, periodic fever and swollen lymph nodes; SWEET syndrome with RAS, periodic fever and significant skin rash, and Cyclic neutropenia with RAS, fever every 15 to 24 days and a low white blood count.. In terms of allergy, RAS is very rarely seen as a response to food allergy, but more commonly as an allergy to tooth paste - especially kinds that contain sodium lauryl sulfate. Very rarely it occurs from chewing gums that contain balsam of Peru.. Factors that predispose to, ...
I was diagnosed with Celiac (by genetic testing) in July and immediately went on the diet in a big way. I was diagnosed with Behcet Disease a couple of months ago. Gastro doc had me go back on gluten for a few weeks and then did an upper endoscopy. Doc said I was inflamed all the way through my body, as far as endoscopy went and they did a lot of biopsies. At my follow up doc said surprisingly celiac biopsies came back negative or whatever....and was surprised....hoped by the looks of my endoscopy that I had Crohns but feared lymphoma and ruling out Crohns would take us the next step to the lymphoma diagnosis. An upper GI series was done last week and a small bowel test. Doc who did those said there were no signs of Crohns, which I already anticipated. I dont understand what the doc saw that really made her fear lymphoma. I am praying that what she is seeing is Behcets Disease, since it is so rare many docs have never seen it first hand. I had outbreaks on my face last spring several times, ...
Dalvi SR, Yildirim R, Yazici Y (December 3, 2012). "Behcet's Syndrome". Drugs. 72 (17): 2223-41. doi:10.2165/11641370-000000000 ... MAGIC syndrome is a possible variant of Behçet disease, and is associated with aphthous-like ulceration. The name stands for " ... Synonyms for major RAS include Sutton's ulcers (named after Richard Lightburn Sutton), Sutton's disease, Sutton's syndrome and ... Other examples of systemic conditions associated with aphthous-like ulceration include reactive arthritis (Reiter's syndrome), ...
Dalvi SR, Yildirim R, Yazici Y (December 3, 2012). "Behcet's Syndrome". Drugs. 72 (17): 2223-41. doi:10.2165/11641370-000000000 ... PFAPA syndrome is a rare condition that tends to occur in children.[8] The name stands for "periodic fever, aphthae, ... Sutton's syndrome and pariadenitis mucosa necrotica recurrens.[2][8] Synonyms for aphthous stomatitis as a whole include ( ... MAGIC syndrome is a possible variant of Behçet disease, and is associated with aphthous-like ulceration. The name stands for " ...
"Behcet's Syndrome: MedlinePlus". nih.gov. Archived from the original on 4 July 2016. Retrieved 19 September 2016.. ... Reactive arthritis, Stevens-Johnson syndrome, Sweet syndrome[1]. Medication. Immunosuppressive medication such as ... Some sources use the term "Adamantiades's syndrome" or "Adamantiades-Behçet syndrome", for the work done by Benediktos ... "A double-blind trial of colchicine in Behcet's syndrome". Arthritis Rheum. 44 (11): 2686-92. doi:10.1002/1529-0131(200111)44:11 ...
Zhou J, Wang Y, Liu Y, Zeng H, et al «Budd-Chiari syndrome in Behcet's disease: A report of two cases» (en anglès). Exp Ther ... Nitecki, SS «Vascular Involvement in Behcet's Disease - Vasculo-Behcet» (en anglès). A: Behcet's Disease - A Compilation of ... Dowling CM, Hill AD, Malone C, Sheehan JJ, et al «Colonic perforation in Behcet's syndrome» (en anglès). World J Gastroenterol ... Behcet's Syndrome: What it is and isn't Vasculitis Foundation. Yazici, Y; 2016, Maig. (anglès) ...
"Behcet's Syndrome: MedlinePlus". nih.gov. Archived from the original on 4 July 2016. Retrieved 19 September 2016. Piga, M; ... "A double-blind trial of colchicine in Behcet's syndrome". Arthritis Rheum. 44 (11): 2686-92. doi:10.1002/1529-0131(200111)44:11 ... "Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome. A randomized, double-blind, placebo- ... "Adamantiades's syndrome" or "Adamantiades-Behçet syndrome", for the work done by Benediktos Adamantiades. However, the current ...
"A double-blind trial of depot corticosteroids in Behcet's syndrome". Rheumatology. 45 (3): 348-52. doi:10.1093/rheumatology/ ... A chest X-ray should be performed to rule out pulmonary diseases, in particular sarcoidosis and Löfgren syndrome. Erythema ... "A double-blind trial of colchicine in Behçet's syndrome". Arthritis & Rheumatism. 44 (11): 2686-92. doi:10.1002/1529-0131( ...
Behcet Syndrome is a multisystem disease also with symptoms similar to JIA. The etiology is unknown and it leads to multisystem ... The additional symptoms and age onset, as Behcet syndrome is rarely diagnosed before school age, can help differentiate. Lyme ...
Mor, F; Weinberger, A; Cohen, IR (2002). "Identification of alpha-tropomyosin as a target self-antigen in Behcet's syndrome". ... tropomyosin antibodies have also been reported in acute rheumatic fever and the inflammatory disorder Behcet's syndrome. In ...
They can occur in patients with Behcet's syndrome, lupus, and some forms of rheumatoid arthritis (all non-communicable diseases ... The syndrome may be further classified into penile ulceration and vulval ulceration for males and females respectively. Genital ...
... behcet syndrome, antiphospholipid antibody syndrome or blunt trauma to the back or abdomen. Treatment of RVT mainly focuses on ... behcet syndrome, antiphospholipid antibody syndrome or blunt trauma to the back or abdomen. Damage to the endothelial tissue of ... The incidence of RVT in people with Nephrotic syndrome ranges from 5% to 65%. Nephrotic syndrome is caused by Membranous ... newly born infants with blood clotting abnormalities or dehydration and adults with nephrotic syndrome. Nephrotic syndrome, a ...
Behcet's Syndrome, pemphigus, herpes simplex, histoplasmosis, and reactive arthritis (Reiter's Syndrome). Nascimento, Marcelle ... Investigations into the influence of polycystic ovarian syndrome on the oral microbiome are continuing. Saliva sampling may be ... The association between the salivary microbiome and with Polycistic Ovarian Syndrome has been characterized. "[S]aliva ... "The Salivary Microbiome in Polycystic Ovary Syndrome (PCOS) and Its Association with Disease-Related Parameters: A Pilot Study ...
Intestinal Tuberculosis and Behcet's Syndrome". The American journal of the medical sciences. 346 (6): 467-72. doi:10.1097/MAJ. ...
... and Behcet's syndrome) has been investigated and compared to other inflammatory biomarkers, such as ESR and WBC. The role of ... intestinal tuberculosis and Behcet's syndrome". The American Journal of the Medical Sciences. 346 (6): 467-72. doi:10.1097/MAJ. ...
Sudden infant death syndrome[medical citation needed] Burning mouth syndrome. Psychogenic polydipsia Idiopathic "Behcet Disease ... Other examples include: Behcet's disease Bell's palsy Schizophrenia Tolosa-Hunt syndrome New daily persistent headache[medical ... Kwan ES, Wolpert SM, Hedges TR, Laucella M (February 1988). "Tolosa-Hunt syndrome revisited: not necessarily a diagnosis of ... Maltsman-Tseikhin, A; Moricca, P; Niv, D (June 2007). "Burning mouth syndrome: will better understanding yield better ...
Sjogren syndrome, myasthenia gravis, systemic vasculitis, Behcet-like syndrome, dermatomyositis, granulomatosis with ... Wiskott-Aldrich syndrome, immunodeficiency with short-limbed dwarfism, immunodeficiency with thymoma, purine nucleoside ... chronic idiopathic neutrophilia Pelger-Huet anomaly Down syndrome Leukocyte adhesion deficiency Familial cold urticaria ...
Behcet's syndrome (136.3) Pneumocystosis (136.4) Psorospermiasis (136.5) Sarcosporidiosis (136.9) Infectious/parasitic diseases ...
Becker's nevus Beemer-Ertbruggen syndrome Beemer-Langer syndrome Behcet syndrome Behr syndrome Behrens-Baumann-Dust syndrome ... sclerosis Bamforth syndrome BANF acoustic neurinoma Bangstad syndrome Banki syndrome Bannayan-Zonana syndrome Banti's syndrome ... syndrome Bonneman-Meinecke-Reich syndrome Bonnemann-Meinecke syndrome Bonnevie-Ullrich-Turner syndrome Book syndrome Boomerang ... syndrome 2 Bare lymphocyte syndrome Baritosis Barnicoat-Baraitser syndrome Barrett syndrome Barrow-Fitzsimmons syndrome Barth ...
Still disease Cutaneous leishmaniasis A similar response occurs in pyoderma gangrenosum and Adamantiades-Behcet's syndrome, and ...
... behcet syndrome MeSH C11.941.879.780.880.400 --- iridocyclitis MeSH C11.941.879.780.880.448 --- iritis MeSH C11.941.879.780.900 ... horner syndrome MeSH C11.710.570 --- mydriasis MeSH C11.710.800 --- tonic pupil MeSH C11.710.800.180 --- adie syndrome MeSH ... dry eye syndromes MeSH C11.496.260.394 --- keratoconjunctivitis sicca MeSH C11.496.260.719 --- sjogren's syndrome MeSH C11.496. ... duane retraction syndrome MeSH C11.590.312 --- miller fisher syndrome MeSH C11.590.400 --- nystagmus, pathologic MeSH C11.590. ...
... syndrome, Buerger's, Behcet's, and Kawasaki disease. Various imaging techniques may be used to diagnose and monitor disease ... Similar symptoms may be caused by a number of other conditions, such as Ehlers-Danlos syndrome and Marfan syndrome (both ...
Sjogren syndrome, thromboangiitis obliterans, Behcet syndrome, IgG4-related disease, inflammatory bowel diseases, sarcoidosis, ... Hypereosinophilic Syndrome research in UK Hypereosinophilic Syndrome on patient.info Hypereosinophilic Syndrome on eMedicine ... Wiskott-Aldrich syndrome (defective WAS gene), IPEX syndrome (defective IPEX gene), CD40 gene defect, and autoimmune ... see mutations in the hymperimmoglobulin E syndrome). Omenn syndrome is a severe combined immuodeficiency disease characterized ...
Beemer-Ertbruggen syndrome. *Beemer-Langer syndrome. *Behcet syndrome. *Behr syndrome. *Behrens-Baumann-Dust syndrome ... chapter 6 epileptic syndromes in infants, childhood and adolescence 4th edition, CHARLOTTE DRAVET MICHELLE BUREAU ...
... syndrome Beare-Stevenson cutis gyrata syndrome Beckwith-Wiedemann syndrome Behcet's syndrome Behr syndrome Benedikt syndrome ... syndrome Wende-Bauckus syndrome Werner syndrome Wernicke-Korsakoff syndrome West syndrome Westerhof syndrome Wet lung syndrome ... syndrome Hero syndrome Heyde's syndrome High-rise syndrome HIV/AIDS Holiday heart syndrome Holt-Oram syndrome Hopkins syndrome ... syndrome Shone's syndrome Short anagen syndrome Short bowel syndrome short limb syndrome Short man syndrome Short QT syndrome ...
... behcet syndrome MeSH C17.800.862.560 --- mucocutaneous lymph node syndrome MeSH C17.800.862.625 --- polyarteritis nodosa MeSH ... tietze's syndrome MeSH C17.300.200.310 --- ehlers-danlos syndrome MeSH C17.300.200.425 --- keloid MeSH C17.300.200.425.125 --- ... stevens-johnson syndrome MeSH C17.800.229.413 --- erythema nodosum MeSH C17.800.229.413.800 --- sweet's syndrome MeSH C17.800. ... caplan's syndrome MeSH C17.300.775.099.389 --- felty's syndrome MeSH C17.300.775.099.683 --- rheumatoid nodule MeSH C17.300. ...
... may also occur in presumed ocular histoplasmosis syndrome (POHS); despite its name, the relationship of POHS to ... Other possible causes of chorioretinitis are syphilis, sarcoidosis, tuberculosis, Behcet's disease, onchocerciasis, or West ... anti-vascular endothelial growth factor therapy for choroidal neovascularization secondary to ocular histoplasmosis syndrome". ...
Immune dysfunction - arthritis, systemic lupus erythematosus, Sjögren syndrome, myasthenia gravis, systemic vasculitis, Behcet- ... Wiskott-Aldrich syndrome, immunodeficiency with short-limbed dwarfism, immunodeficiency with thymoma, purine nucleoside ...
Behcets syndrome (or disease) causes inflammation of the blood vessels and symptoms in many parts of the body. Learn about ... Behcets syndrome is a disease that involves vasculitis, which is inflammation of the blood vessels. It causes problems in many ... Behcets Disease (Johns Hopkins Vasculitis Center) * Behcets Disease (National Institute of Arthritis and Musculoskeletal and ... The primary NIH organization for research on Behcets Syndrome is the National Institute of Arthritis and Musculoskeletal and ...
Behcets syndrome is a rare condition where blood vessels all throughout the body become abnormally inflamed, explains Mayo ... What is CREST syndrome?. A: CREST syndrome is a skin condition that causes hardened skin on the lower arms, legs, face and ... In many cases, the symptoms of Behcets syndrome last a few weeks and then go away, but they can return and also cause scarring ... Behcets syndrome is a rare condition where blood vessels all throughout the body become abnormally inflamed, explains Mayo ...
can anyone plz give some information on the Behcet sydrome i heard and read online that it can be treated with chinese herbs ... I need some information on the Behcets syndrome?. can anyone plz give some information on the Behcet sydrome i heard and read ...
Click on a [studies] link to search within your current results for studies in that region. Use the back button to return to this list and try another region ...
Treatments and Tools for behcet syndrome. Find behcet syndrome information, treatments for behcet syndrome and behcet syndrome ... MedHelps behcet syndrome Center for Information, Symptoms, Resources, ... My daughter has Behcets Disease. She has been told she cant have laser eye surgery for he... ... I have been suspected for behcet disease last year , I am having headache everyday since ch... ...
This program will help you understand Behcets syndrome, including symptoms and causes. It also covers the diagnosis and ... Behcets Syndrome. This program will help you understand Behcets syndrome, including symptoms and causes. It also covers the ...
... is showing promise in the treatment of Behcets syndrome. - News - PharmaTimes ... is showing promise in the treatment of Behcets syndrome.. Phase II data has been presented at the American College of ... In the study, 111 people with Behcets (who did not have any organs affected by disease and had at least two ulcers at the ... Rheumatology meeting in San Diego on apremilast for Behcets, a rare and chronic inflammatory disorder characterised by oral ...
Behcets syndrome. I. What every physician needs to know.. Behcets syndrome (BS) is a rare, chronic, relapsing multisystem ... Behcets syndrome*I. What every physician needs to know.*II. Diagnostic Confirmation: Are you sure your patient has Behcets ... C. History Part 3: Competing diagnoses that can mimic disease Behcets syndrome.. Crohns disease. Ulcers in BS are usually ... C. History Part 3: Competing diagnoses that can mimic disease Behcets syndrome.*Crohns disease*Reactive Arthritis (formerly ...
Behcets Syndrome Society: It is difficult to understand why all trials are not registered and published, to date the current ...
Behcets Syndrome Wednesday, May 18, 2016. 12:00 noon Eastern. Register here for the free webinar. ... in the areas of RA and Behcets syndrome. ... for Joint Diseases and Director of the Behcets Syndrome ... monitoring of arthritis patients in regard to clinical response and adverse events related to treatment and Behcets syndrome. ...
... general Behcets disease Care and treatment Case studies Diagnosis Behcets syndrome Central nervous system diseases Spinal ... Anterior spinal cord syndrome in a patient with behcets disease.(Clinical report) by Bulletin of the NYU Hospital for Joint ... behcet%27s+disease.-a0301086219. *APA style: Anterior spinal cord syndrome in a patient with behcets disease.. (n.d.) >The ... Behcet syndrome. Curr Opin Rheumatol. 2004 Jan; 16(1):38-42. (2.) Serdaroglu P, Yazici H, Ozdemir C, et al. Neurologic ...
Keywords:Behcets disease, Behcets syndrome, chronic disease, depression.. Abstract:Behcets syndrome (BD) is a controversial ... Depression as a Comorbidity in Behcets Syndrome. Author(s): Natalia P. de Oliveira Ribeiro, Alexandre R. de Mello Schier, ... Behcets syndrome (BD) is a controversial, chronic, and episodic condition that is autoimmune in origin and causes systemic ... "Depression as a Comorbidity in Behcets Syndrome", CNS & Neurological Disorders - Drug Targets (2014) 13: 1041. https://doi.org ...
Behcet Syndrome. Eosinophilia. Cryopyrin-Associated Periodic Syndromes. Syndrome. Disease. Pathologic Processes. Mouth Diseases ... A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcets Disease. The safety ... A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome (FCAS) / Muckle-Wells Syndrome (MWS) and Behcets Disease ... Muckle-Wells Syndrome Wells Syndrome Cryopyrin-associated Periodic Syndrome Panuveitis Uveal Diseases Familial Mediterranean ...
Patient experience of genitourinary syndrome of menopause. Take Quiz. Symptoms of genitourinary syndrome of menopause. Take ... Hepatopulmonary syndrome symptoms. Take Quiz. USPSTF recommendations: Screening for celiac disease in asymptomatic persons. ... Hidradenitis suppurativa and polycystic ovarian syndrome. Take Quiz. Associations of infections with hidradenitis suppurativa. ...
A clinical case of neuro-Behcet syndrome without mucocutaneo-ocular symptoms : Relationship with brain stem encephalitis * * ... A clinical comparative study of multiple sclerosis and neuro-Behcets syndrome MOTOMURA S. ... The combined use of HLA-B5 and the pathergy test as diagnostic markers of Behcets disease in Turkey YAZICI H ... Skin prick test (needle reaction) of Behcets disease ; procedure and significance as a clinical test INABA G ...
FRI0351 Papulopustular lesions according to age, sex and localization in behcets syndrome patients compared healthy and ... FRI0351 Papulopustular lesions according to age, sex and localization in behcets syndrome patients compared healthy and ... Background Papulopustular lesions (PPL) are the most common skin lesions in Behçets syndrome (BS). ...
MalaCards integrated aliases for Autoinflammatory Syndrome, Familial, Behcet-Like:. Name: Autoinflammatory Syndrome, Familial, ... Behcet-Like, is also known as aisbl. An important gene associated with Autoinflammatory Syndrome, Familial, Behcet-Like is ... ClinVar genetic disease variations for Autoinflammatory Syndrome, Familial, Behcet-Like:. 6 (show all 12) #. Gene. Variation. ... Human phenotypes related to Autoinflammatory Syndrome, Familial, Behcet-Like:. 32 (show all 12) #. Description. HPO Frequency. ...
Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behcets syndrome patients ZORA Wartung. Maintenance ... Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behcets syndrome patients. International Immunology ... Behçets syndrome (BS) is a systemic inflammatory disorder with unknown etiology. Features of both innate and adaptive immunity ... Behçets syndrome (BS) is a systemic inflammatory disorder with unknown etiology. Features of both innate and adaptive immunity ...
The doctor Im seeing now has only had two other Behcets patients. Do you know anything about Behcets syndrome, or how I can ... I am a 37-year-old female and have been diagnosed with Behcets syndrome. I had never heard of it before that time. It is very ... I was surprised recently to get several questions from people who have Behcets syndrome, since it is a rare condition - at ... What Can You Tell Me About Behcets Syndrome?. « Severe Migraine Headache Treatments , Is Prostate Surgery Necessary » ...
It is not known to be hereditary in its complete form but the syndrome described here is caused by a gene and is transmissible ... Behcet disease is a poorly understood disorder of inflammation in several organ systems including the gastrointestinal tract, ...
By admin 2007 Behcets Syndrome, Extensive Gastrointestinal Involvement 0 Comments This article has been written by Ehtesham ... Extensive Gastrointestinal Involvement in Behcets Syndrome - A Case Report Ehtesham Khalid, Aflak Rasheed, Nabila Khalid, ... Extra Intestinal Manifestations of Irritable Bowel Syndrome Azeem Taj, Abdul Shakoor, Tafazzul-c-Haquc Mahmud, Naeema Afzal, ...
Behcets and Marriage. eyes. I fear that he will one day find it all too much to be with someone who has a chronic illness and ... I think any change in hormones may be the issue and that exacerbates any Behcets symptoms I have. In the last year, Ive also ... Anyway, If anyone knows about helping the hormone issues and Behcets symptoms, Id love to hear about it. Ive been trying for ...
Myelodysplastic syndrome (MDS) is a heterogeneous group of stem cell disorders of unknown etiology. Behcet disease (BD) is a ... Successful treatment of myelodysplastic syndrome and Behcet colitis after allogeneic hematopoietic stem cell transplantation. ... 4. International Study Group for Behcets Disease. Criteria for diagnosis of Behcets disease. Lancet 1990;335:1078-1080PMID : ... 1B). There was no need to treat for Behcet colitis. At the time of this report, the patient was doing well in complete ...
I have an illness called Behcets disease. Very rare. When I returned from Iraq one day while at home I went to sleep, woke up ... I am in a state of remission with Behcets but my leg has never come back on line, ever. I allso have urinary incontince and ...
Ive been told that I am the only one in all of Manitoba with a known case of Behcets Disease, so I understand that he doesnt ... Tampa Bay (USA) is one of the areas that does studies on Behcets, so I am fortunate. But even so, most of the doctors here are ... Join a Behcets Organization that educates on all the particulars of this syndrom. They keep you updated on the newest findings ... My rheumatologist sounds much like your old one, as he was able to diagnose me with Behcets, but hasnt really been trying to ...
  • Dr. Yazici is also the Director of the Seligman Center for Advanced Therapeutics at the NYU Hospital for Joint Diseases and Director of the Behcet's Syndrome Evaluation, Treatment and Research Center at NYU Hospital for Joint Diseases. (vasculitisfoundation.org)
  • The monogenic forms of these diseases are also classified as the hereditary periodic fever syndromes. (nih.gov)
  • The other rather common monogenic diseases are the tumor necrosis factor receptor-associated periodic syndrome, hyperimmunoglobulinemia D with periodic fever syndrome, and cryopyrin-associated periodic fever syndromes (CAPS). (nih.gov)
  • Diseases associated with GIMAP4 include Behcet Syndrome . (genecards.org)
  • A chest X-ray should be performed to rule out pulmonary diseases, in particular sarcoidosis and Löfgren syndrome. (wikipedia.org)
  • They can occur in patients with Behcet's syndrome, lupus, and some forms of rheumatoid arthritis (all non-communicable diseases). (wikipedia.org)
  • 133) Acariasis (133.0) Scabies (133.8) Other acariasis Chiggers (133.9) Acariasis unspecified (134) Other infestation (134.0) Myiasis (134.1) Other arthropod infestation (134.2) Hirudiniasis (134.8) Other specified infestations (134.9) Infestation unspecified (135) Sarcoidosis (136) Other and unspecified infectious and parasitic diseases (136.0) Ainhum (136.1) Behcet's syndrome (136.3) Pneumocystosis (136.4) Psorospermiasis (136.5) Sarcosporidiosis (136.9) Infectious/parasitic diseases, unspec. (wikipedia.org)
  • Aortic dissection is more common in those with a history of high blood pressure, a number of connective tissue diseases that affect blood vessel wall strength such as Marfan syndrome, a bicuspid aortic valve, and previous heart surgery. (wikipedia.org)
  • EN is associated with a wide variety of conditions, including: Idiopathic In about 30-50% of cases, the cause of EN is unknown. (wikipedia.org)
  • The World Health Organization classifies these disorders into a) Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1 (i.e. high eosinophil blood counts caused by mutations in the eosinophil cell line of one of these three genes), 'b) Chronic eosinophilic leukemia, and c) the Idiopathic hypereosinophiic syndrome. (wikipedia.org)
  • Behcet Syndrome is a medical condition in which a relapsing chronic inflammatory disorder that may produce painful, recurring skin blisters, mouth sores, swollen joints, or genital sores, occurs. (unitedhealthdirectory.com)
  • Behcet's syndrome is a rare inflammatory multisystem disorder that is genetically linked and is still under research to identify a suitable cure. (medindia.net)
  • Guillain-Barre syndrome (GBS), also known as an acute inflammatory demyelinating polyneuropathy, is an acute demyelinating polyradiculopathy of uncertain etiology. (bvsalud.org)
  • This study shows that a functional variant of miR-196a2 confers risk for BD but not for VKH syndrome or AAU(+)AS(+) by modulating the miR-196a gene expression and by regulating pro-inflammatory IL-1β and MCP-1 production. (cdc.gov)
  • Caselli RJ in 1999 reported five patients, age 54 to 80 years, presented between 3 weeks and 18 months after symptomatic onset of progressive cognitive decline, psychosis, and unsteady gait that proved to be due to a steroid-responsive nonvasculitic autoimmune inflammatory meningoencephalitic syndrome. (wikipedia.org)
  • Journal of Dr. Behcet Uz Children's Hospital" is indexed by the Web of Science-Emerging Sources Citation Index, EBSCO, Google Scholar, Microsoft Academic Search, T B TAK/ULAKB M, T rk Medline and the Turkish Citation Index. (behcetuzdergisi.com)
  • First described by German pathologist Friedrich Daniel von Recklinghausen in 1861, RVT most commonly affects two subpopulations: newly born infants with blood clotting abnormalities or dehydration and adults with nephrotic syndrome. (wikipedia.org)
  • Nephrotic syndrome, a kidney disorder, causes excessive loss of protein in the urine, hypoalbuminemia, hypercholesterolemia and edema, triggering a hypercoagulable state and increasing chances of clot formation. (wikipedia.org)
  • Membranous Glomerulonephritis, the most common cause for nephrotic syndrome in adults, peaks in people ages 40-60 years old and It is twice as likely to occur in men than in women. (wikipedia.org)
  • Since nephrotic syndrome is the most common cause of RVT, people over 40 years old and men are most at risk to develop a renal vein thrombosis. (wikipedia.org)
  • Nephrotic syndrome patients have a higher risk of RVT development due to hypercoagulability caused by proteinuria. (wikipedia.org)
  • The increased loss of proteins in the urine caused by nephrotic syndrome results in lower osmotic pressure. (wikipedia.org)
  • Other than nephrotic syndrome, there are many other factors that can promote hypercoagulability. (wikipedia.org)
  • This disorder is distinguished from 1) eosinophilia, which is an elevation in this count above normal levels of 5.0 x 109/L (i.e. 500/μl) but below the hypereosinophilia cutoff level and 2) the hypereosinophilic syndrome, which is a sustained elevation in this count above 15.0 x 109/L (i.e. 1,500/μl) that is also associated with evidence of eosinophil-based tissue injury. (wikipedia.org)
  • Many patients with BD often complain about abdominal tenderness, bloating, and generic abdominal discomfort that closely mimics irritable bowel syndrome. (wikipedia.org)
  • He divides his time between seeing patients and running the Seligman center, conducting both industry and investigator initiated trials, in the areas of RA and Behcet's syndrome. (vasculitisfoundation.org)
  • This rare syndrome is caused by hypoperfusion of the anterior spinal artery, leading to ischemia in the anterior two thirds of the spinal cord, and to our knowledge has not been previously reported in patients with BD. (thefreelibrary.com)
  • The treatment of MDS-related Behcet colitis is usually diff icult to manage, and many patients eventually die of infection or hemorrhage. (kjim.org)
  • About 50% of patients with Behcet's syndrome may have a relatively mild, nonprogressive knee arthritis and other large joints. (unitedhealthdirectory.com)
  • Johns Hopkins Medicine reports that the HLA-B51 gene is found in some patients with Behcet's syndrome, though the presence of the gene alone does not cause Behcet's. (colgate.com)
  • Conclusion: Sweet syndrome should be kept in mind when erythematous rashes develop in patients with febrile neutropenia who have been using G-CSF for a long time and who have not been able to control their fever despite appropriate antibiotics and antifungals. (behcetuzdergisi.com)
  • A two-stage association study was carried out in 988 VKH syndrome patients,400 BD patients and 976 healthy controls. (cdc.gov)
  • The first stage study showed that the frequency of the A allele of rs6498169 was significantly decreased in VKH syndrome patients (Pc = 1.1 × 10(-2), OR = 0.7, 95%CI = 0.6-0.9). (cdc.gov)
  • No significant association was observed in the other 7 SNPs between VKH syndrome patients and controls. (cdc.gov)
  • A two-stage association study was carried out in 859 BD, 400 VKH syndrome, 209 AAU(+)AS(+) patients and 1,685 controls all belonging to a Chinese Han population. (cdc.gov)
  • A total of 656 BD patients, 961 VKH syndrome patients and 1534 healthy controls were included in this two-stage case control study. (cdc.gov)
  • Skin hypersensitivity is seen in most Behcet patients with pus and redness of the skin developing within 24 hours at the site of a pinprick into sterile skin. (healthcentral.com)
  • We herein report a case of intractable MDS-related Behcet colitis that was successfully treated by allogeneic hematopoietic stem cell transplantation (HSCT). (kjim.org)
  • It is not known to be hereditary in its complete form but the syndrome described here is caused by a gene and is transmissible in some families. (arizona.edu)