A pathological condition caused by impaired blood flow in the basal regions of cerebral hemispheres (BASAL GANGLIA), such as INFARCTION; HEMORRHAGE; or ISCHEMIA in vessels of this brain region including the lateral lenticulostriate arteries. Primary clinical manifestations include involuntary movements (DYSKINESIAS) and muscle weakness (HEMIPARESIS).
Large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
Clusters of multipolar neurons surrounded by a capsule of loosely organized CONNECTIVE TISSUE located outside the CENTRAL NERVOUS SYSTEM.
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
Pathologic deposition of calcium salts in tissues.
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.
Value of all final goods and services produced in a country in one year.
An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.
Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.

Two types of auditory neglect. (1/36)

Auditory neglect, defined as inattention to stimuli within the left hemispace, is mostly reported in association with left ear extinction in dichotic listening. However, it remains disputed as to how far dichotic extinction reflects a primary attentional deficit and is thus appropriate for the diagnosis of auditory neglect. We report here on four patients who presented left ear extinction in dichotic listening following right unilateral hemispheric lesions. Auditory spatial attention was assessed with two additional tasks: (i) diotic test by means of interaural time differences (ITDs), simulating bilateral simultaneous spatial presentation of the dichotic tasks without the inconvenience of interaural intensity or content difference; and (ii) sound localization. A hemispatial asymmetry on the ITD diotic test or a spatial bias on sound localization were found to be part of auditory neglect. Two patients (J.C.N. and M.B.) presented a marked hemispatial asymmetry favouring the ipsilesional hemispace in the ITD diotic test, but did not show any spatial bias in sound localization. Two other patients (A.J. and E.S.) had the reverse profile: no hemispatial asymmetry in the ITD diotic test, but a severe spatial bias directed to the ipsilesional side in sound localization. J.C.N. and M.B. had mainly subcortical lesions affecting the basal ganglia. A.J. and E.S. had cortical lesions in the prefrontal, superior temporal and inferior parietal areas. Thus, there are two behaviourally and anatomically distinct types of auditory neglect characterized by: (i) deficit in allocation of auditory spatial attention following lesions centred on basal ganglia; or (ii) distortion of auditory spatial representation following frontotemporoparietal lesions.  (+info)

Correlation of early CT signs in the deep middle cerebral artery territories with angiographically confirmed site of arterial occlusion. (2/36)

BACKGROUND AND PURPOSE: Early CT signs in the deep middle cerebral artery (MCA) territories have been reported to be seen at the initial period of ischemia. We attempted to investigate the incidence of parenchymal hypodensity within 3 hours after ischemic onset among patients with angiographically proved embolic MCA occlusion and to assess the correlation of subtle hypodensity in the deep MCA territories with involvement of the lenticulostriate arteries in the presence of ischemia. METHODS: Fifty CT images obtained within 3 hours after onset of embolic MCA occlusion were retrospectively reviewed by three neurosurgeons who were aware of clinical features. Early CT signs in the deep MCA territories were divided into three grades according to their anatomic location: grade I, normal basal ganglia with hypodensity localized to the insula; grade II, partial obscuration of the posterolateral part of the putamen; and grade III, hypodensity of the entire lentiform nucleus. A grade I CT sign was considered to be a negative finding for lenticulostriate artery involvement, whereas grade II and III CT signs were considered to be positive findings. Site of occlusion and involvement of the lenticulostriate arteries were confirmed by angiography. RESULTS: Thirty-eight (76%) of 50 patients had early CT signs in the deep MCA territories. Sensitivity and specificity of a grade I CT sign indicating absence of lenticulostriate artery involvement in ischemia were 65% and 87%, respectively. On the other hand, sensitivity and specificity of grade II and grade III CT signs for presence of lenticulostriate artery involvement in ischemia were 77% and 100%, respectively. Grade II CT signs resulted from various sites of occlusion, whereas grade III was unequivocally predictive of proximal occlusion to all of the lenticulostriate arteries. CONCLUSION: Involvement of the lenticulostriate arteries may be presumed by precise evaluation of subtle, CT-revealed hypodensity in the deep MCA territories, even within 3 hours of ischemic onset.  (+info)

Small centrum ovale infarcts on diffusion-weighted magnetic resonance imaging. (3/36)

BACKGROUND AND PURPOSE: A small centrum ovale infarct (SCOI), caused by occlusion of the white matter medullary arteries, is often equated with a lacunar infarct. We sought to clarify the clinical characteristics of a SCOI visualized by diffusion-weighted MRI (DWI) compared with those of a small basal ganglia infarct (SBGI). METHODS: Patients with a SCOI (SCOI group; n=38) or SBGI (SBGI group; n=68) < or =15 mm in diameter on conventional MRI and DWI were selected from 582 consecutive patients with acute ischemic stroke. Sex, age, neurological symptoms, vascular risk factors, emboligenic heart disease, arterial occlusive disease in the ipsilateral carotid system, and recurrent stroke within the initial 30 days were compared between the 2 groups. RESULTS: Only 47% of SCOIs but 87% of SBGIs could be identified with the use of conventional MRI, whereas DWI could detect them all. Age, sex, and vascular risk factors were not significantly different between the 2 groups. The SCOI group had more frequently an abrupt onset of symptoms (63% versus 26%; P=0.0002), emboligenic heart diseases (34% versus 12%; P=0.0054), occlusive carotid and/or middle cerebral artery diseases (53% versus 19%; P=0.0004), and recurrent stroke (13% versus 1%; P=0.0216) but less frequently a classic lacunar syndrome (50% versus 81%; P=0.0009) than the SBGI group. On a multivariate analysis, both arterial and heart diseases were independently associated with the SCOI group. CONCLUSIONS: Symptomatic SCOIs detected by DWI may be associated with large-vessel and heart diseases and should be distinguished from lacunar infarcts.  (+info)

Cerebrovascular disease and evolution of depressive symptoms in the cardiovascular health study. (4/36)

BACKGROUND AND PURPOSE: Previous studies have reported an association between cerebrovascular disease and depressive symptoms. The Cardiovascular Health Study (CHS) provides an opportunity to examine the relationship between vascular brain pathology seen on neuroimaging and changes in depressive symptoms. METHODS: The sample included 3236 CHS participants who had an MRI brain scan. Demographic variables, medical history, functional status, and apolipoprotein E genotype were obtained at baseline. Annual scores on a modified version of the Centers for Epidemiologic Studies Depression (CES-D) scale were obtained initially and up to 7 years subsequently. RESULTS: After controlling for important covariates, occurrence of depressive symptoms (defined as modified CES-D score of >7) was associated with small lesions in the basal ganglia, large cortical white-matter lesions, and severe subcortical white-matter grade. Neuroimaging variables did not predict incident depression among those who were nondepressive at the time of MRI. Persistence of depressive symptoms across 2 consecutive time points was associated with small basal ganglia lesions and large cerebral cortical white-matter lesions. Worsening of depression (increase in CES-D score of > or =5) was associated with subcortical white-matter lesions. CONCLUSIONS: These findings suggest that cerebrovascular disease at baseline is related to depression symptoms over time. Further studies are needed to investigate the differential effects of subcortical white- versus gray-matter lesions on mood.  (+info)

Early and late postnatal identification of isolated lenticulostriate vasculopathy in preterm infants: associated findings. (5/36)

OBJECTIVES: To determine the incidence, possible etiologies, and neurodevelopmental outcome of premature infants (<35 weeks) with isolated lenticulostriate vasculopathy (LSV). STUDY DESIGN: In a retrospective case-control design, we reviewed the medical records of all premature infants who were admitted to our neonatal intensive care unit between 1996 and 2000. RESULTS: The prevalence of LSV was 4.6% (21 of 453). Patients with late LSV (detected after 10 days of age) had less exposure than controls to prenatal steroids [42.8% (6 of 14) vs. 92.8% (13 of 14), respectively; p<0.01], and prenatal antibiotics [42.8% (6 of 14) vs. 85.7% (12 of 14), respectively; p=0.01]. Fifty-seven percent (8 of 14) of patients with late LSV had a low Apgar score vs. 14.2% (2 of 14) of the control group (p=0.01). Patients with LSV also had more muscle tone abnormalities than controls at 6 months of age [33.3% (5 of 15) vs. 5.2% (1 of 19), respectively; p=0.03]. CONCLUSION: Patients with late LSV have less exposure to antenatal steroids and antibiotics, lower Apgar scores, and abnormal muscle tone at 6 months of age.  (+info)

Heterogeneity of cerebral blood flow in Alzheimer disease and vascular dementia. (6/36)

BACKGROUND AND PURPOSE: Alzheimer disease (AD) and vascular dementia (VaD) are the two major diseases that cause dementia, and early diagnosis is important. Single photon emission CT (SPECT) of cerebral blood flow (CBF) is used for the early detection of dementia and as an auxiliary method for follow-up. AD shows reduced posterior blood flow and VaD manifests reduced anterior blood flow on CBF SPECT images. We examined the usefulness of 3D fractal analysis of CBF SPECT images to objectively quantify the heterogeneity of CBF in patients with AD and VaD. METHODS: Thirty-two patients with AD and 22 with VaD based on neuropsychologic tests and imaging findings, as well as 20 age-matched control subjects underwent technetium-99m hexamethyl propyleneamine oxime CBF SPECT. We then conducted statistical image processing by 3D fractal analysis on reconstructed data. Fractal dimension, an index of heterogeneity, was then calculated for the whole brain, as well as for the anterior and posterior regions of the brain. A higher fractal dimension indicates that the CBF SPECT image is uneven. The ratio of fractal dimension of the anterior region to fractal dimension of the posterior region (A/P ratio) was calculated. Heterogeneity of CBF was compared among the AD, VaD, and control groups. RESULTS: Fractal dimensions of the AD, VaD, and control groups were 1.072+/-0.179 (mean +/- SD), 1.005+/-0.156, and 0.806+/-0.06, respectively. A significant difference of fractal dimension was noted between the control group and the two types of dementia (P<.0001); however, no significant difference was noted between the AD and VaD groups. The A/P ratios of the AD and VaD groups were significantly different (0.952 and 1.163, respectively; P<.01). CONCLUSION: Analysis of CBF SPECT images quantitatively showed that the fractal dimension was significantly higher (indicating heterogeneity) in patients with AD and VaD when compared with age-matched control subjects. Comparison of the A/P ratio on CBF SPECT images between AD and VaD groups showed that the heterogeneity of CBF was posterior-dominant for AD and anterior-dominant for VaD. Thus, 3D fractal analysis enabled a simple and objective evaluation of the heterogeneity of CBF in patients with AD and VaD.  (+info)

Neonatal lenticulostriate vasculopathy: further characterisation. (7/36)

BACKGROUND: Lenticulostriate vasculopathy (LSV) is sometimes detected on routine brain ultrasonography in neonates, and is often associated with various perinatal and neonatal abnormalities. However, most reports on LSV are retrospective with no controls. OBJECTIVES: To compare the perinatal and neonatal clinical characteristics of neonates with LSV with matched controls and to summarise all published reports of LSV. DESIGN: A prospective study that summarises the clinical, laboratory, and neurosonographic data of neonates with LSV. METHODS: Of 1184 neonates admitted to the neonatal intensive care unit (NICU) during a three year period, 857 had a routine head ultrasound examination. Twenty one had LSV, and were compared with 42 matched controls with regard to gestational, perinatal, neonatal, laboratory, and neurosonographic characteristics. RESULTS: LSV was detected in 21 of the 857 (2.45%) neonates. It was bilateral in 10 of the 21 cases and located in the thalamus (n = 14) and basal ganglia (n = 7). Infants with LSV were not significantly different from matched controls in most tested variables. However, compared with the control group, the LSV group included significantly more multiple births and more disturbances in amniotic fluid volume, but less meconial amniotic fluid. In addition, the patients with LSV required fewer blood transfusions and less phototherapy. CONCLUSIONS: Except for more multiple births, neonates with LSV did not display more adverse findings than their matched controls.  (+info)

The L-dopa response in vascular parkinsonism. (8/36)

OBJECTIVE: To determine whether a positive L-dopa response in vascular parkinsonism (VP) is correlated with the presence of nigrostriatal pathology due to either vascular damage or neuronal cell loss. METHODS: Seventeen patients with pathologically confirmed VP were selected from the pathological collection of the Queen Square Brain Bank for Neurological Disorders, and their L-dopa response during life was compared with the presence of macroscopic vascular damage in the nigrostriatal pathway and microscopic substantia nigra cell loss. RESULTS: Ten of the twelve patients with a good or excellent response had macroscopic infarcts or lacunae caused by enlarged perivascular spaces in the basal ganglia or microscopic neuronal cell loss in the substantia nigra. In contrast, only one of the five patients with a moderate or no response had lacunae in the putamen, and none had lacunar infarcts or substantia nigra cell loss. CONCLUSION: These results suggest that a substantial number of patients with clinically suspected VP may respond with benefit to dopaminergic therapy, especially those with lesions in or close to the nigrostriatal pathway.  (+info)

Basal ganglia cerebrovascular disease refers to a type of stroke or brain injury that affects the basal ganglia, which are clusters of nerve cells located deep within the brain. These structures play a crucial role in controlling movement and coordination.

Cerebrovascular disease occurs when blood flow to the brain is disrupted due to blockage or rupture of blood vessels. In the case of basal ganglia cerebrovascular disease, this disruption specifically affects the blood supply to the basal ganglia. This can result in damage to the nerve cells in this region and lead to various symptoms, depending on the severity and location of the injury.

Symptoms of basal ganglia cerebrovascular disease may include:

* Hemiplegia or weakness on one side of the body
* Rigidity or stiffness of muscles
* Tremors or involuntary movements
* Difficulty with coordination and balance
* Speech and language difficulties
* Changes in cognitive function, such as memory loss or difficulty with problem-solving

Treatment for basal ganglia cerebrovascular disease typically involves addressing the underlying cause of the disrupted blood flow, such as through medication to control blood pressure or cholesterol levels, surgery to remove blockages or repair ruptured blood vessels, or rehabilitation therapy to help manage symptoms and improve function.

The basal ganglia are a group of interconnected nuclei, or clusters of neurons, located in the base of the brain. They play a crucial role in regulating motor function, cognition, and emotion. The main components of the basal ganglia include the striatum (made up of the caudate nucleus, putamen, and ventral striatum), globus pallidus (divided into external and internal segments), subthalamic nucleus, and substantia nigra (with its pars compacta and pars reticulata).

The basal ganglia receive input from various regions of the cerebral cortex and other brain areas. They process this information and send output back to the thalamus and cortex, helping to modulate and coordinate movement. The basal ganglia also contribute to higher cognitive functions such as learning, decision-making, and habit formation. Dysfunction in the basal ganglia can lead to neurological disorders like Parkinson's disease, Huntington's disease, and dystonia.

Cerebrovascular disorders are a group of medical conditions that affect the blood vessels of the brain. These disorders can be caused by narrowing, blockage, or rupture of the blood vessels, leading to decreased blood flow and oxygen supply to the brain. The most common types of cerebrovascular disorders include:

1. Stroke: A stroke occurs when a blood vessel in the brain becomes blocked or bursts, causing a lack of oxygen and nutrients to reach brain cells. This can lead to permanent damage or death of brain tissue.
2. Transient ischemic attack (TIA): Also known as a "mini-stroke," a TIA occurs when blood flow to the brain is temporarily blocked, often by a blood clot. Symptoms may last only a few minutes to a few hours and typically resolve on their own. However, a TIA is a serious warning sign that a full-blown stroke may occur in the future.
3. Aneurysm: An aneurysm is a weakened or bulging area in the wall of a blood vessel. If left untreated, an aneurysm can rupture and cause bleeding in the brain.
4. Arteriovenous malformation (AVM): An AVM is a tangled mass of abnormal blood vessels that connect arteries and veins. This can lead to bleeding in the brain or stroke.
5. Carotid stenosis: Carotid stenosis occurs when the carotid arteries, which supply blood to the brain, become narrowed or blocked due to plaque buildup. This can increase the risk of stroke.
6. Vertebrobasilar insufficiency: This condition occurs when the vertebral and basilar arteries, which supply blood to the back of the brain, become narrowed or blocked. This can lead to symptoms such as dizziness, vertigo, and difficulty swallowing.

Cerebrovascular disorders are a leading cause of disability and death worldwide. Risk factors for these conditions include age, high blood pressure, smoking, diabetes, high cholesterol, and family history. Treatment may involve medications, surgery, or lifestyle changes to reduce the risk of further complications.

Basal ganglia diseases are a group of neurological disorders that affect the function of the basal ganglia, which are clusters of nerve cells located deep within the brain. The basal ganglia play a crucial role in controlling movement and coordination. When they are damaged or degenerate, it can result in various motor symptoms such as tremors, rigidity, bradykinesia (slowness of movement), and difficulty with balance and walking.

Some examples of basal ganglia diseases include:

1. Parkinson's disease - a progressive disorder that affects movement due to the death of dopamine-producing cells in the basal ganglia.
2. Huntington's disease - an inherited neurodegenerative disorder that causes uncontrolled movements, emotional problems, and cognitive decline.
3. Dystonia - a movement disorder characterized by sustained or intermittent muscle contractions that cause twisting and repetitive movements or abnormal postures.
4. Wilson's disease - a rare genetic disorder that causes excessive copper accumulation in the liver and brain, leading to neurological and psychiatric symptoms.
5. Progressive supranuclear palsy (PSP) - a rare brain disorder that affects movement, gait, and balance, as well as speech and swallowing.
6. Corticobasal degeneration (CBD) - a rare neurological disorder characterized by progressive loss of nerve cells in the cerebral cortex and basal ganglia, leading to stiffness, rigidity, and difficulty with movement and coordination.

Treatment for basal ganglia diseases varies depending on the specific diagnosis and symptoms but may include medication, surgery, physical therapy, or a combination of these approaches.

A ganglion is a cluster of neuron cell bodies in the peripheral nervous system. Ganglia are typically associated with nerves and serve as sites for sensory processing, integration, and relay of information between the periphery and the central nervous system (CNS). The two main types of ganglia are sensory ganglia, which contain pseudounipolar neurons that transmit sensory information to the CNS, and autonomic ganglia, which contain multipolar neurons that control involuntary physiological functions.

Examples of sensory ganglia include dorsal root ganglia (DRG), which are associated with spinal nerves, and cranial nerve ganglia, such as the trigeminal ganglion. Autonomic ganglia can be further divided into sympathetic and parasympathetic ganglia, which regulate different aspects of the autonomic nervous system.

It's worth noting that in anatomy, "ganglion" refers to a group of nerve cell bodies, while in clinical contexts, "ganglion" is often used to describe a specific type of cystic structure that forms near joints or tendons, typically in the wrist or foot. These ganglia are not related to the peripheral nervous system's ganglia but rather are fluid-filled sacs that may cause discomfort or pain due to their size or location.

MedlinePlus is not a medical term, but rather a consumer health website that provides high-quality, accurate, and reliable health information, written in easy-to-understand language. It is produced by the U.S. National Library of Medicine, the world's largest medical library, and is widely recognized as a trusted source of health information.

MedlinePlus offers information on various health topics, including conditions, diseases, tests, treatments, and wellness. It also provides access to drug information, medical dictionary, and encyclopedia, as well as links to clinical trials, medical news, and patient organizations. The website is available in both English and Spanish and can be accessed for free.

Calcinosis is a medical condition characterized by the abnormal deposit of calcium salts in various tissues of the body, commonly under the skin or in the muscles and tendons. These calcium deposits can form hard lumps or nodules that can cause pain, inflammation, and restricted mobility. Calcinosis can occur as a complication of other medical conditions, such as autoimmune disorders, kidney disease, and hypercalcemia (high levels of calcium in the blood). In some cases, the cause of calcinosis may be unknown. Treatment for calcinosis depends on the underlying cause and may include medications to manage calcium levels, physical therapy, and surgical removal of large deposits.

Vascular calcification is a pathological process characterized by the deposition of calcium phosphate crystals in the blood vessels, particularly in the tunica intima (the innermost layer) of the arterial wall. This condition can lead to the stiffening and hardening of the arteries, which can impair their ability to expand and contract with each beat of the heart. Vascular calcification is often associated with various cardiovascular diseases such as atherosclerosis, diabetes, chronic kidney disease, and aging. It can contribute to an increased risk of cardiovascular events such as myocardial infarction, stroke, and peripheral artery disease.

Physiologic calcification is the normal deposit of calcium salts in body tissues and organs. It is a natural process that occurs as part of the growth and development of the human body, as well as during the repair and remodeling of tissues.

Calcium is an essential mineral that plays a critical role in many bodily functions, including bone formation, muscle contraction, nerve impulse transmission, and blood clotting. In order to maintain proper levels of calcium in the body, excess calcium that is not needed for these functions may be deposited in various tissues as a normal part of the aging process.

Physiologic calcification typically occurs in areas such as the walls of blood vessels, the lungs, and the heart valves. While these calcifications are generally harmless, they can sometimes lead to complications, particularly if they occur in large amounts or in sensitive areas. For example, calcification of the coronary arteries can increase the risk of heart disease, while calcification of the lung tissue can cause respiratory symptoms.

It is important to note that pathologic calcification, on the other hand, refers to the abnormal deposit of calcium salts in tissues and organs, which can be caused by various medical conditions such as chronic kidney disease, hyperparathyroidism, and certain infections. Pathologic calcification is not a normal process and can lead to serious health complications if left untreated.

I'm sorry for any confusion, but "Gross Domestic Product" (GDP) is an economic term, not a medical one. GDP is the total monetary or market value of all the finished goods and services produced within a country's borders in a specific time period. It serves as a comprehensive measure of a nation’s overall economic activity.

If you have any medical questions or terms you would like defined, I would be happy to help!

Brain chemistry refers to the chemical processes that occur within the brain, particularly those involving neurotransmitters, neuromodulators, and neuropeptides. These chemicals are responsible for transmitting signals between neurons (nerve cells) in the brain, allowing for various cognitive, emotional, and physical functions.

Neurotransmitters are chemical messengers that transmit signals across the synapse (the tiny gap between two neurons). Examples of neurotransmitters include dopamine, serotonin, norepinephrine, GABA (gamma-aminobutyric acid), and glutamate. Each neurotransmitter has a specific role in brain function, such as regulating mood, motivation, attention, memory, and movement.

Neuromodulators are chemicals that modify the effects of neurotransmitters on neurons. They can enhance or inhibit the transmission of signals between neurons, thereby modulating brain activity. Examples of neuromodulators include acetylcholine, histamine, and substance P.

Neuropeptides are small protein-like molecules that act as neurotransmitters or neuromodulators. They play a role in various physiological functions, such as pain perception, stress response, and reward processing. Examples of neuropeptides include endorphins, enkephalins, and oxytocin.

Abnormalities in brain chemistry can lead to various neurological and psychiatric conditions, such as depression, anxiety disorders, schizophrenia, Parkinson's disease, and Alzheimer's disease. Understanding brain chemistry is crucial for developing effective treatments for these conditions.

... basal ganglia diseases MeSH C10.228.140.079.127 - basal ganglia cerebrovascular disease MeSH C10.228.140.079.127.500 - basal ... basal ganglia cerebrovascular disease MeSH C10.228.140.300.100.200 - basal ganglia hemorrhage MeSH C10.228.140.300.100.200.500 ... lewy body disease MeSH C10.228.140.079.862.500 - parkinson disease MeSH C10.228.140.079.862.800 - parkinson disease, secondary ... lewy body disease MeSH C10.228.662.600.400 - parkinson disease MeSH C10.228.662.600.700 - parkinson disease, secondary MeSH ...
... basal ganglia cerebrovascular disease MeSH C14.907.253.061.200 - basal ganglia hemorrhage MeSH C14.907.253.061.200.500 - ... basal ganglia hemorrhage MeSH C14.907.253.420.150.500 - putaminal hemorrhage MeSH C14.907.253.420.200 - cerebral hemorrhage, ... basal ganglia hemorrhage MeSH C14.907.253.573.200.150.500 - putaminal hemorrhage MeSH C14.907.253.573.200.200 - cerebral ... intracranial arterial diseases MeSH C14.907.253.560.200 - cerebral arterial diseases MeSH C14.907.253.560.200.175 - cadasil ...
... basal ganglia and thalamus has recently been used as a successful treatment for tremors of patients with Parkinson's disease. ... These conditions are listed below: Central nervous system tumor Central pontine myelinolysis Cerebrovascular diseases Drug ... Treatment was based on the theory that there is an imbalance of the neurotransmitter dopamine in the basal ganglia. These drugs ... Although no lesions are present in the basal ganglia in primary spasmodic torticollis, fMRI and PET studies have shown ...
... and the caudate nucleus of the basal ganglia may implicate dementia due to arteriosclerotic microvascular disease, in ... Because dilated perivascular spaces are so closely correlated with cerebrovascular disease, there is much current research on ... In contrast to VRS of the basal ganglia, VRS in the cerebral cortex are surrounded by only one layer of leptomeninges. As such ... have noted the greater frequency of β-amyloid plaques in the cerebral cortex than in the basal ganglia of Alzheimer's disease ...
Furthermore, it has also been hypothesized that pathways that connect the basal ganglia with the cortex and thalamus is ... cerebrovascular disease, neoplasms, head injury, and some metabolic conditions (homocystinuria, diabetic ketoacidosis, hepatic ... Parkinson's disease can be distinguished from catatonia by a positive response to levodopa. Catatonia on the other hand will ... Further complicating the diagnosis is the fact that many patients with Parkinson's disease will have major depressive disorder ...
... of microglia that exist within the basal ganglia circuitry to one day target regional or circuit-specific microglia in disease ... from 1990s), neuroscientist known for her books on hypertension, cerebrovascular permeability, vascular stress, and cerebral ... from 1970s) physician and neuroscientist working on neurodegenerative diseases, including Huntington's disease and Parkinson's ... neuroscientist specializing on the basal ganglia and the neurophysiology of habit formation Carla Green (born 1962), ...
... basal ganglia output nucleus). This dysfunction with the basal ganglia and PFC may explain the executive function and semantic ... cerebrovascular disease, pre-existing neurological disease, severe substance abuse compatible with CNS disorder. While the ... including the basal ganglia, deep white matter, and hippocampal regions. Neuroimaging studies of HIV patients indicate that ... hypertrophy is apparent in the basal ganglia, especially the putamen. Moreover, the results of some studies suggest loss of ...
BBB disruption is associated with hypertension, cerebrovascular diseases, neurodegenerative diseases, and aging. Inflammation ... and basal ganglia, and cause cell death and tissue degeneration. Blood clots also accelerate arterioscelerosis, which causes ... Diseases that can cause secondary hypertension include diabetic nephropathy, glomerular disease, polycystic kidney disease, ... Most often, there are no definite symptoms to this disease. There are some signs that one could look for to deduce it is ...
Hemorrhage into the basal ganglia or thalamus causes contralateral hemiplegia due to damage to the internal capsule. Other ... It accounts for 20% of all cases of cerebrovascular disease in the United States, behind cerebral thrombosis (40%) and cerebral ... Aspiration by stereotactic surgery or endoscopic drainage may be used in basal ganglia hemorrhages, although successful reports ... Cerebrovascular diseases, Neurotrauma, Wikipedia medicine articles ready to translate, Wikipedia neurology articles ready to ...
GA1 can be described as a metabolic disorder, a neurometabolic disease, a cerebral palsy or a basal ganglia disorder (it may ... cerebrovascular abrupt and severe neonatal asphyxia ("selective neuronal necrosis"). In a cohort of 279 patients who had been ... So-called "orphan diseases", such as GA1, can be adopted into wider groups of diseases (such as carnitine deficiency diseases, ... These intermediate breakdown products are particularly prone to affect the basal ganglia, causing many of the signs and ...
In contrast, after a stroke, people with moderate anosognosia have a higher frequency of lesions involving the basal ganglia, ... Orfei MD, Caltagirone C, Spalletta G (2009). "The evaluation of anosognosia in stroke patients". Cerebrovascular Diseases. 27 ( ... The term is from Ancient Greek ἀ- a-, 'without', νόσος nosos, 'disease' and γνῶσις gnōsis, 'knowledge'. It is also considered a ... Starkstein SE, Fedoroff JP, Price TR, Leiguarda R, Robinson RG (October 1992). "Anosognosia in patients with cerebrovascular ...
According to fMRI studies, the acquisition of procedural memories activates the basal ganglia, the premotor cortex and the ... Ribot, T. (1882). Diseases of Memory: An essay in the positive psychology. London: D. Appleton and company. Scoville, W.B.; ... The damage is usually caused by head trauma, cerebrovascular accident, stroke, tumor, hypoxia, encephalitis, or chronic ... Amnesia is a deficit in memory caused by brain damage or disease, but it can also be caused temporarily by the use of various ...
This has been shown to be related to decreased activation in the basal ganglia and frontal cortex. Elgh, Domellof, Linder, ... Alzheimer's disease (AD) is a progressive, degenerative and fatal brain disease, in which cell to cell connections in the brain ... can also be the result of a stroke as the resulting lack of oxygen can cause damage to the location of the cerebrovascular ... Parkinson's disease (PD) is a neurodegenerative disease. PD and aging share a lot of the same neuropathologic and behavioral ...
... most often the lenticulostriate vessels of the basal ganglia, and are associated with chronic hypertension. Charcot-Bouchard ... Cerebrovascular diseases, Neurosurgery). ... This can be because of acquired disease or hereditary factors. ... An intracranial aneurysm, also known as a cerebral aneurysm, is a cerebrovascular disorder in which weakness in the wall of a ... 2005). Robbins and Cotran Pathologic Basis of Disease (7th ed.). China: Elsevier. ISBN 978-0-7216-0187-8.[page needed] Gupta, ...
Adults with cerebral palsy may have ischemic heart disease, cerebrovascular disease, cancer, and trauma more often. Obesity in ... Dyskinetic cerebral palsy (sometimes abbreviated DCP) is primarily associated with damage to the basal ganglia and the ... Cheney PD (1997). "Pathophysiology of the corticospinal system and basal ganglia in cerebral palsy". Mental Retardation and ... Chronic disease risk, such as obesity, is also higher among adults with cerebral palsy than the general population. Common ...
... and thereby lowers the levels of dopamine in the basal ganglia neurons and leads to the Parkinson's symptoms. Additionally, ... or a genetic predisposition to the disease are more likely to develop the drug induced form of this disease as a result of ... Clinical pharmacology and therapeutic role in cerebrovascular disorders". Drugs. 26 (1): 44-69. doi:10.2165/00003495-198326010- ... Cinnarizine is predominantly used to treat nausea and vomiting associated with motion sickness, vertigo, Ménière's disease, or ...
... s are most often located in the lenticulostriate vessels of the basal ganglia and are associated with ... Cerebrovascular diseases). ... Robbins and Cotran Pathologic Basis of Disease (7th ed.). ...
... in individuals with Parkinson's disease, as well as in individuals with other disorders affecting basal ganglia circuitry, are ... Marie described the case of a Frenchman who started speaking in an Alsatian accent after a cerebrovascular accident caused ... It has also been found that damage to the medulla, cerebellum, and basal ganglia may cause dysprosody. These conclusions have ... Vanlanckersidtis, D; Pachana, N; Cummings, J; Sidtis, J (2006). "Dysprosodic speech following basal ganglia insult: Toward a ...
... the parietal and basal ganglia regions are often affected in degenerative brain diseases associated with aging and it has ... cerebrovascular disease, Parkinson's disease, and Lou Gehrig's disease. While much research has focused on diseases of aging, ... "Regional Cerebral Blood Flow Changes in Healthy Ageing and Alzheimer's Disease: A Narrative Review". Cerebrovascular Diseases. ... A significant age-related decline especially in the parietal gray matter, basal ganglia, and to a lesser degree, the frontal ...
The vessels that supply the subcortical white matter come from the vessels that support basal ganglia, internal capsule, and ... Cerebrovascular diseases, Rare diseases). ... There are many diseases similar to Binswanger's disease ... Alzheimer renamed this disease Binswanger's disease. In the late 19th century vascular dementia was heavily studied, however by ... The complicated history of Binswanger's disease and the fact that it was overlooked as a disease for many years means some ...
Diffuse white matter changes (leukoencephalopathy) and multiple lacunar infarcts in the basal ganglia of the thalamus are ... Journal of Stroke and Cerebrovascular Diseases, 20(2), 85-86,87,88,89,90,91. Onodera, Osamu; Nozaki, Hiroaki; Fukutake, Toshio ... Several disease that are frequently used for differential diagnoses include Binswanger's disease, CADASIL, Nasu-Hakula disease ... CARASIL is an autosomal recessive disease, meaning that both parents must be a carrier for the allele in order for the disease ...
Chutinet A, Rost NS (March 2014). "White matter disease as a biomarker for long-term cerebrovascular disease and dementia". ... the subcortical basal ganglia (hypothalamus, thalamus, putamen), and the mammillary bodies. Antipsychotic Corticosteroid use ( ... and vascular dementia Pick's disease, causes progressive destruction of nerve cells in the brain Huntington's disease, and ... Many diseases that cause cerebral atrophy are associated with dementia, seizures, and a group of language disorders called the ...
2005). "Cerebrovascular Diseases". Adams and Victor's Principles of Neurology. New York: McGraw-Hill. ISBN 978-0-07-141620-7. ... These lesions are concentrated around the basal ganglia, peri-ventricular white matter, and the pons, and are similar to those ... Cerebrovascular diseases, Skin conditions resulting from errors in metabolism, Syndromes). ... although MRI is able to detect signs of the disease years prior to clinical manifestation of disease. The condition was ...
Journal of Stroke and Cerebrovascular Diseases. 6 (5): 368-369. doi:10.1016/s1052-3057(97)80220-0. PMID 17895035. Morgan, J. R ... "Neuropsychological alterations in patients with computed tomography-detected basal ganglia calcification". Archives of ... Diagnosis of Crohn's disease was made within 5 to 13 years."(Blanchet C, Luton JP. 2002)"This disease should be diagnostically ... Addison's disease is a disorder of the adrenal cortex which results in decreased hormonal production. Addison's disease, even ...
... rather than deep white matter or basal ganglia. These are usually described as "lobar". These bleedings are not associated with ... Cerebrovascular diseases). ... Sympathomimetic drug abuse Moyamoya disease Sickle cell disease ... and lung cancer are the most common causes of hemorrhage from metastatic disease. Other causes of intraparenchymal hemorrhage ...
Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain". Brain Research ... Cholinergic neurons have an effect on other neurodegenerative diseases such as Parkinson's disease, Huntington's disease and ... impairments in cerebrovascular function, and basal forebrain cholinergic deficits in AD. It appears that Beta amyloid (1-42) ... Auld DS, Kornecook TJ, Bastianetto S, Quirion R (October 2002). "Alzheimer's disease and the basal forebrain cholinergic system ...
Glenner GG; Wong CW (1984). "Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril ... the basal ganglia and diencephalon are affected; in Phase 4, plaques appear in the midbrain and medulla oblongata; and in Phase ... are important early events in the pathogenesis of Alzheimer's disease. Until recently, the diagnosis of Alzheimer's disease ... Thus, in end-stage Alzheimer's disease, plaques can be found in most parts of the brain. They are uncommon in the spinal cord. ...
Possible sites of lesions include the thalamus, internal capsule, and basal ganglia. While aphasia has traditionally been ... Associated conditions In a study on the features associated with different disease trajectories in Alzheimer's disease (AD)- ... After a traumatic brain injury (TBI) or cerebrovascular accident (CVA), the brain undergoes several healing and re-organization ... and the caudate nucleus of the basal ganglia. The area and extent of brain damage or atrophy will determine the type of aphasia ...
... basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system. The ... heart disease) and lungs (lung disease). Cardiovascular disease - (CVD), is a class of diseases that involve the heart or blood ... and cerebrovascular system. Nose - The human nose is the most protruding part of the face. It bears the nostrils and is the ... congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease ...
Journal of Stroke and Cerebrovascular Diseases. 25 (11): 2770-2779. doi:10.1016/j.jstrokecerebrovasdis.2016.07.033. PMID ... the alteration in dopaminergic neurons in the substantia nigra and contributes to optimal functioning of the basal ganglia ... Grazina R, Massano J (2013). "Physical exercise and Parkinson's disease: influence on symptoms, disease course and prevention ... particularly Alzheimer's disease and Parkinson's disease. Regular exercise is also associated with a lower risk of developing ...
... obtain a history of neurologic disorders that may involve the basal ganglia (eg, cerebrovascular disease, encephalitis, head ... Support for the hypothesis that TD may result from blockade of postsynaptic dopamine receptors in the basal ganglia and other ... In Fahr syndrome, calcification is often seen in the brain, particularly in the basal ganglia. Imaging results can also exclude ... Hypothesized pathways among basal ganglia and other structures of the central nervous system ...
... basal ganglia diseases MeSH C10.228.140.079.127 - basal ganglia cerebrovascular disease MeSH C10.228.140.079.127.500 - basal ... basal ganglia cerebrovascular disease MeSH C10.228.140.300.100.200 - basal ganglia hemorrhage MeSH C10.228.140.300.100.200.500 ... lewy body disease MeSH C10.228.140.079.862.500 - parkinson disease MeSH C10.228.140.079.862.800 - parkinson disease, secondary ... lewy body disease MeSH C10.228.662.600.400 - parkinson disease MeSH C10.228.662.600.700 - parkinson disease, secondary MeSH ...
Basal Ganglia Vascular Disease Cerebrovascular Disease, Basal Ganglia Vascular Disease, Basal Ganglia Vascular Diseases, Basal ... Angiopathies des ganglions de la base Entry term(s):. Basal Ganglia Vascular Disease. Cerebrovascular Disease, Basal Ganglia. ... Vascular Disease, Basal Ganglia. Vascular Disease, Lenticulostriate. Vascular Diseases, Basal Ganglia. Vascular Diseases, ... Basal Ganglia Cerebrovascular Disease Descriptor Spanish: Enfermedad Cerebrovascular de los Ganglios Basales Spanish from Spain ...
BASAL GANGLIA CEREBROVASCULAR DISEASE ENFERMEDAD CEREBROVASCULAR DE LOS GANGLIOS BASALES DOENÇA CEREBROVASCULAR DOS GÂNGLIOS DA ... CEREBROVASCULAR ACCIDENT ACCIDENTE CEREBROVASCULAR ACIDENTE CEREBROVASCULAR CEREBROVASCULAR TRAUMA TRAUMATISMOS ... BASAL NUCLEUS OF MEYNERT NUCLEO BASAL DE MEYNERT NÚCLEO BASAL DE MEYNERT ... DISEASE ATTRIBUTES ATRIBUTOS DE ENFERMEDAD ATRIBUTOS DE DOENÇA DISEASE MODELS, AUTOIMMUNE, NERVOUS SYSTEM MODELOS DE ENFERMEDAD ...
BASAL GANGLIA CEREBROVASCULAR DISEASE ENFERMEDAD CEREBROVASCULAR DE LOS GANGLIOS BASALES DOENÇA CEREBROVASCULAR DOS GÂNGLIOS DA ... CEREBROVASCULAR ACCIDENT ACCIDENTE CEREBROVASCULAR ACIDENTE CEREBROVASCULAR CEREBROVASCULAR TRAUMA TRAUMATISMOS ... BASAL NUCLEUS OF MEYNERT NUCLEO BASAL DE MEYNERT NÚCLEO BASAL DE MEYNERT ... DISEASE ATTRIBUTES ATRIBUTOS DE ENFERMEDAD ATRIBUTOS DE DOENÇA DISEASE MODELS, AUTOIMMUNE, NERVOUS SYSTEM MODELOS DE ENFERMEDAD ...
The mean duration time of the SLE to detection of the basal ganglia calcification is 7.62 years (3 days-31 years). ... cerebrovascular disease, psychosis, and acute confusional state, transverse myelitis, and demyelinating syndrome. ... There are approximately 29 patients reported in the literature, with calcifications in the basal ganglia associated with ... Inflammatory joint diseases (58%), connective tissue diseases (18%) and vasculitis (12%) were the most frequent diagnostic ...
... obtain a history of neurologic disorders that may involve the basal ganglia (eg, cerebrovascular disease, encephalitis, head ... Support for the hypothesis that TD may result from blockade of postsynaptic dopamine receptors in the basal ganglia and other ... In Fahr syndrome, calcification is often seen in the brain, particularly in the basal ganglia. Imaging results can also exclude ... Hypothesized pathways among basal ganglia and other structures of the central nervous system ...
From Geremia G, Greenlee W. In Atlas of Cerebrovascular Disease. Edited by PB Gorelick and MA Sloan. Philadelphia, Current ... Note the loss of gray-white matter differentiation (circle), hypoxic-ischemic damage to the basal ganglia (arrows), and ... In children, sickle cell disease Sickle Cell Disease Sickle cell disease (a hemoglobinopathy) causes a chronic hemolytic anemia ... From Geremia G, Greenlee W. In Atlas of Cerebrovascular Disease. Edited by PB Gorelick and MA Sloan. Philadelphia, Current ...
... it has recently also been detected to be useful in analysing the soft tissue of the brain stem and the basal ganglia in ... and modalities fighting the threat of stroke and its underlying cerebrovascular diseases. Ultrasound-based prevention will play ... to the use of ultrasound techniques for the detection and investigation of the cerebrovascular system in health and disease. In ...
... basal ganglia). A variety of movement disorders, including Parkinsons disease and Huntingtons disease, involve the basal ... Vascular disorders. Usually, with a sudden onset of signs and symptoms, cerebrovascular disease often occurs in the setting of ... These disorders often affect the basal ganglia bilaterally, but if there is unilateral disease, the movement disorder will ... However, the unilaterality of the motor deficits pointed to bleeding in the basal ganglia and internal capsule rather than in ...
Significance and translational value of high-frequency cortico-basal ganglia oscillations in Parkinsons disease. Petersson, P. ... Distinctive Effects of D1 and D2 Receptor Agonists on Cortico-Basal Ganglia Oscillations in a Rodent Model of L-DOPA-Induced ... Translating scientific advances into disease-modifying therapies for Parkinsons Disease. Cenci, M. A. & Olanow, C. W., 2017 ... Andreoli, L., Abbaszadeh, M., Cao, X. & Cenci, M. A., 2021 Sept 1, In: Neurobiology of Disease. 157, 105429.. Research output: ...
Auditory Diseases, Central (0) * Basal Ganglia Diseases (11) * Brain Damage, Chronic (1) ... Cerebellar Diseases (19) * Cerebrovascular Disorders (142) * Dementia (6115) * Diffuse Cerebral Sclerosis Of Schilder (1) ... Articles by Disease Articles By Disease Bentham is offering subject-based scholarly content collections which are tailored to ...
However, the possibility of unilateral cerebrovascular events may be overlooked because of the lack of laterality of disease ... Computed tomography of the brain revealed acute extensive intraparenchymal hemorrhage involving the right basal ganglia, ... the patient did not suffer much neurological sequelae from the disease. ...
... drug-induced Parkinsonism and cerebrovascular disease (Bonifati, 2014).. Pathophysiology of the disease. The main ... nerve cells in the brain or damage of the nerve cells causes reduction in the secretion of dopamine mainly in the basal ganglia ... pathophysiology of the disease and impact of the disease on the disease on the HRQoL of the individuals and the family of ... The PHP for Parkinsons disease in Australia is mostly aimed towards identification of the disease specific age groups and ...
Catalog of Genes and Diseases from OMIM. *BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 1; IBGC1 ... Genetic Testing Registry: Basal ganglia calcification, idiopathic, 4 *Genetic Testing Registry: Basal ganglia calcification, ... Genetic Testing Registry: Basal ganglia calcification, idiopathic, 5 *Genetic Testing Registry: Idiopathic basal ganglia ... Cerebrovascular ferrocalcinosis. *Familial idiopathic basal ganglia calcification. *FIBGC. *Striopallidodentate calcinosis. ...
Affects ability of CNS to control body movements as a result of Impaired function of basal ganglia in the midbrain. Neurons ... Coronary Heart Disease. 12.4.1. Myocardial infarction. 12.4.1.1. Patho: caused by blockage or clot forming in the coronary ... Cerebrovascular Accidents. 14.3.1. Patho: Can be ischemic or hemmorhagic causing compromise and damage to the brain. Need to ... 12.2.1. Most prevalent cardiac disease in older adults. 12.2.2. Patho: high blood pressure due to the amount of resistance to ...
... but signal abnormalities may be seen in the basal ganglia, thalamus, and brain stem of patients with encephalitis, and in the ... and cerebrovascular disease are risk factors also remains uncertain (27). The clinical severity of WNV encephalitis ranges from ... Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; †Centers for Disease Control and ... Edward B. Hayes, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort ...
... often seen in basal ganglia alteration (mainly in tumour, traumatic lesions and cerebrovascular accident), which might exert an ... Parkinsons Disease: cognitive and behavioural aspects. MORETTI, Rita;Torre P;Antonello R.M. 2013-01-01. Abstract. Basal ... often seen in basal ganglia alteration (mainly in tumour, traumatic lesions and cerebrovascular accident), which might exert an ... Basal ganglia are traditionally related to motor disorders; the most typical confirm of this thought has been the sentence ...
... bances involving the basal ganglia and cerebral cortex. ... Huntingtons disease (HD) is an adult onset inherited ... carotid ultrasonography, cerebral blood flow (xenon-133 injection), and cerebrovascular risk factors. In the group with white ... Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, ... OBJECTIVES: Neonates with single ventricle congenital heart disease are at risk for structural cerebral abnormalities. Little ...
Minimally invasive endoscopic hematoma evacuation vs best medical management for spontaneous basal-ganglia intracerebral ... Cerebrovascular Diseases. 2019 Jan 1 ...
Cerebrovascular Disease and Ischemia. *Place: Poster (Hall No.2 Building, Kobe International Exhibition Hall) ... Basal Ganglia. *Place: Poster (Hall No.1 Building, Kobe International Exhibition Hall) ... Basal Ganglia. *Place: Poster (Hall No.1 Building, Kobe International Exhibition Hall) ... Alzheimers Disease, Other Dementia, Aging I. *Place: Room 3 (Reception Hall, Kobe International Conference Center) ...
Basal Ganglia Diseases 1 0 Cerebellar Neoplasms 1 0 Primary Graft Dysfunction 1 1 ... Cerebrovascular Accident 1 0 Chronic Disease 1 0 Papillomavirus Infections 1 0 ... Deficiency Diseases 1 0 Note: The number of publications displayed in this table will differ from the number displayed in the ... reflects all text searches of the disease term including the indexed term and corresponding children terms. ...
... including both neurodegenerative diseases and vascular disease. Dementia is most common in elderly individuals, with advancing ... A: Hematoxylin-eosin-Luxol fast blue staining of the basal ganglia at 100× magnification demonstrates a cavitary infarct. ... Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants. Ann N Y Acad Sci. 2002 Nov. 977:9- ... Alzheimer Disease. Alzheimer disease (AD) is the most common neurodegenerative disease responsible for dementia. About half of ...
... involves cerebrovascular amyloid deposition and is classified into several types accor... ... Microbleeds in Alzheimer disease are more related to cerebral amyloid angiopathy than cerebrovascular disease. Dement Geriatr ... fected,6 whereas CAA is uncommon in the basal ganglia, thalamus, brainstem, and white matter. In mild CAA, a small proportion ... Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimers disease. ...
basal ganglia disease + baylisascariasis Beta-Ureidopropionase Deficiency Blister + BRAIN ABNORMALITIES, NEURODEGENERATION, AND ... Diseases Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental ... Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease ... cerebrovascular disease + Choristoma + Chronic Brain Damage + Chronic Brain Injury + Colpocephaly complex cortical dysplasia ...
Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinsons Disease. N Engl J Med. 2020 05 14; 382(20):1926-1932. ... The regional pattern of abnormal cerebrovascular reactivity in HIV-infected, virally suppressed women. J Neurovirol. 2020 10; ... "Basal Ganglia" by people in UAMS Profiles by year, and whether "Basal Ganglia" was a major or minor topic of these publications ... "Basal Ganglia" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ...
... in the basal ganglia.[. 12 ]. It is generally believed that the etiology of T-MCA results from an embryonic abnormality in ... In normal cerebrovascular development, a web of small vessels known as the plexus or twigs first forms from the primitive ... T-MCA is often misdiagnosed as MMD or other MCA degenerative steno-occlusive diseases, which are the most common differential ... 12. Kuroda S, Fujimura M, Takahashi J, Kataoka H, Ogasawara K, Iwama T. Diagnostic criteria for moyamoya disease-2021 revised ...
The central dopamine blocking effect has activity on the basal ganglia (nigrostriatal bundles). Haloperidol causes efficient ... Treatment of mild to moderate chorea in Huntingtons disease, when other medicinal products are ineffective or not tolerated ... there was an approximately 3-fold increased risk of cerebrovascular adverse events with some atypical antipsychotics. ... The activity on the basal ganglia probably underlies the undesirable extrapyramidal motor effects (dystonia, akathisia and ...
Neurophysiology of Basal Ganglia. The basal ganglia [BG] are comprised of a number of nuclei in the subcortical region. They ... Moreover, sustained hypertension leads to vascular disease and possibly early myocardial infarction and cerebro-vascular ... Keywords: Adenosine A2A receptors, Basal ganglia, Caffeine, Dopamine D2 receptor, Parkinsons disease, α-synuclein.. ... Functional neuroanatomy of the basal ganglia in Parkinsons disease. Adv Neurol 2003; 91: 9-18.. PubMed ...
The Syndrome of Cutaneous Photosensitivity, Growth Failure, and Basal Ganglia Calcification. Neurol 87:e56-e57, Saini, A.G.,et ... Cerebrovascular Complications of Fabrys Disease. Ann Neurol 40:8-17, Mitsias,P.&Levine,S.R., 1996 ... Cerebrovascular Complications in Ehlers-Danlos Syndrome Type IV. Ann Neurol 38:960-964, North,K.N.,et al, 1995 ... Livedo Reticularis & Cerebrovascular Lesions (Sneddons Syndrome) , Clin, Radiolog & Path Features in Eight Cases. Brain 106: ...
  • In addition, it has recently also been detected to be useful in analysing the soft tissue of the brain stem and the basal ganglia in movement disorders and dementias. (neurosonology-bg.com)
  • Symptoms of the following disorders can be similar to those of moyamoya disease. (vendigig.com)
  • comTransient splenial lesion of the corpus callosum can be observed in various diseases such as cancer, drug use, metabolic disorders, and cerebrovascular disorders, as well as in patients with infectious diseases. (accjournal.org)
  • Impulsivity was evaluated using the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS). (e-jmd.org)
  • In the past, localized functions of the human brain have been conjectured by closely observing the clinical signs in patients who incurred insults to parts of the brain as a result of trauma or cerebrovascular disorders. (jnss.org)
  • This group includes lysosomal storage disorders, various mitochondrial diseases, other neurometabolic disorders, and several other miscellaneous disorders. (medscape.com)
  • Moreover, it must be considered the effective role of white matter alterations, often seen in basal ganglia alteration (mainly in tumour, traumatic lesions and cerebrovascular accident), which might exert an extension or a modification of the possible confined effect due to a limited and selected lesion of one of the nuclei of the basal ganglia domain. (units.it)
  • During the coronavirus disease 2019 (COVID-19) pandemic, there were increasing reports of these lesions being detected on brain imaging tests performed in patients with neurological symptoms. (accjournal.org)
  • Computed tomography of the brain revealed acute extensive intraparenchymal hemorrhage involving the right basal ganglia, frontal lobe, and temporal lobe. (afpm.org.my)
  • CAA was described as a cause of normotensive cerebral hemorrhage in older individuals or also described in studies focusing on its close association with Alzheimer's disease (AD). (docksci.com)
  • Till Parkinson and Charcot, many Autohors have tried to describe what they find during their long-time observational periods at the bed of different patients, with acute cerebral stroke in the basal ganglia regions, or affected by cerebral tumours. (units.it)
  • A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused an outbreak of severe pneumonia (coronavirus disease 2019 [COVID-19]) in China that rapidly spread throughout the globe. (rsna.org)
  • Recent evidence highlights a relatively high percentage (36%) of central nervous system symptoms, including headache, altered mental status, acute cerebrovascular disease, and epilepsy, in patients with COVID-19 ( 1 ). (rsna.org)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • neuronal activity within basal ganglia with areas of the prefrontal cortex is more related to voluntary deliberation, motivation and complex perception of the self, and the disruption of these circuits lead to higher -order deficits (Middleton and Strick, 2000). (units.it)
  • A brain disease that is characterized by pressure on the intracranial tissues by an effusion of blood or cerebrospinal fluid, an abscess, a neoplasm, a depressed fracture of the skull, or edema of the brain. (mcw.edu)
  • These malfunctions lead to disruption in the synchronization between different parts of the brain like ganglia, thalamus and cortex leading defects in neuro-transmission and ultimately development of Parkinsonism (Bastide et al. (onlinenursinganswers.com)
  • In children, there is a higher incidence of AVMs in the posterior fossa, basal ganglia, and thalamus, which are more prone to bleeding and may result in catastrophic outcomes. (aapmr.org)
  • Researchers suggest that calcium deposits lead to the features of primary familial brain calcification by disrupting the connections between the basal ganglia and other areas of the brain, particularly the frontal lobes. (medlineplus.gov)
  • In explaining this, the paper will throw brief light on the causes of the disease development, pathophysiology of the disease and impact of the disease on the disease on the HRQoL of the individuals and the family of carers. (onlinenursinganswers.com)
  • Doppler ultrasound now allows assessment of the pathophysiology av P Kumar · 2010 · Citerat av 115 - generative disorder, characterized by progressively worsening chorea, cognitive and psychiatric distur- bances involving the basal ganglia and cerebral cortex. (firebaseapp.com)
  • 23 ] The most important differential diagnosis is moyamoya disease (MMD), which involves spontaneous progressive steno-occlusion of the internal carotid artery (ICA) and abnormal collateral blood channels (moyamoya vessels) in the basal ganglia. (surgicalneurologyint.com)
  • 6. Axial brain MRI T2WI, at level of basal cisterns (B) and basal ganglia (C) demonstrate void signals (red arrows) of moyamoya collaterals. (vendigig.com)
  • Patients with this arteriopathy that occurs either on a familial or idiopathic basis are said to have moyamoya disease. (vendigig.com)
  • The incidence in European populations is estimated to be about 10% of that observed in Japan.2, Moyamoya disease can occur at any age, however, the age of presentation follows a bimodal distribution. (vendigig.com)
  • Hirotsune N, Meguro T, Kawada S, Nakashima H, Ohmoto T. Long-term follow-up study of patients with unilateral moyamoya disease. (vendigig.com)
  • Moyamoya disease is a progressive disorder that affects the blood vessels in the brain (cerebrovascular). (vendigig.com)
  • Medical progress: moyamoya disease and moyamoya syndrome. (vendigig.com)
  • Results of more than 20 years of follow-up in pediatric patients with moyamoya disease undergoing pial synangiosis [published online ahead of print, 2019 Mar 1]. (vendigig.com)
  • Moyamoya disease is uncommon in the nonAsian population with an incidence of 0.086 per 100,000 people in the US, although that number may underrepresent the total cases of arteriopathy, including people with sickle cell disease and other cohorts outside of those with Asian ancestry. (vendigig.com)
  • 2015). The following paper aims to analyse one such chronic health condition, Parkinson's disease, a neurodegerative dis-order with progressive impairment in the cognitive and motor functioning. (onlinenursinganswers.com)
  • Approximately 15% of patients follow a primary progressive or progressive relapsing course from disease onset, usually characterized by symptoms of progressive myelopathy (gait instability, spasticity, bladder symptoms) and cognitive impairment. (medscape.com)
  • Multiple neuropathologic processes may underlie dementia , including both neurodegenerative diseases and vascular disease. (medscape.com)
  • [ 2 ] All dementia share common molecular mechanisms responsible for disease etiology and progression, such as hypoxia and oxidative stress, neuroinflammation, mitochondrial bioenergetics, neurodegeneration, and blood-brain barrier permeability. (medscape.com)
  • Alzheimer disease (AD) is the most common neurodegenerative disease responsible for dementia. (medscape.com)
  • Mutations of presenilin genes Down syndrome Cystatin C (ACys) HCHWA-Icelandic type (HCHWA-I) associated with a mutation (68Leu→Gln) of the cystatin C gene Prion protein (PrP) (APrP) Prion disease associated with mutations of the PRNP gene (Y145Stop, Y163Stop, Y226Stop) ABri/ADan Familial British or Danish dementia (FBD/FDD) associated with mutations of the BRI gene. (docksci.com)
  • Parkinson's disease (PD) hampers the health-related quality of life (HRQoL) of both the diseased individual and their family of carers (Nandipati & Litvan, 2016). (onlinenursinganswers.com)
  • The paper will also analyse the health promotion strategies towards the self-management of Parkinson's and importance of culturally safe care towards the promotion of the disease empowerment. (onlinenursinganswers.com)
  • Damage of the brain is mainly attributed to the damage of the nerves leading to the development of neurogenerative disease, Parkinson's. (onlinenursinganswers.com)
  • This loss of nerve cells is a slow process and thus the symptoms of Parkinson's disease only start to develop when 80% of the nerve cells in the substantia nigra region of the brain have been lost. (onlinenursinganswers.com)
  • This is due to this genetic linkage of the Parkinson's disease makes in inherited and might run in families (Bonifati, 2014). (onlinenursinganswers.com)
  • According to Parkinson's Australia (2018) people living with PD require re-adjustment as the progress of disease is slow. (onlinenursinganswers.com)
  • Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease. (uams.edu)
  • Parkinson's disease [PD] is the second most common neurodegenerative disorder after Alzheimer's disease, affecting 1% of the population over the age of 55. (openneurologyjournal.com)
  • Motor and nonmotor symptoms were significantly correlated with the Parkinson's Disease Questionnaire-39 summary index. (e-jmd.org)
  • Frequency of Impulsive-Compulsive Behavior and Associated Psychological Factors in Parkinson's Disease: Lack of Control or Too Much of It? (e-jmd.org)
  • Basal Ganglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • Prevention of stroke is an extremely important requirement for modern societies, and modalities fighting the threat of stroke and its underlying cerebrovascular diseases. (neurosonology-bg.com)
  • Choose a chronic disease from the list below and critically discuss how you would support self-management of your client/patient living with this chronic illness in the community. (onlinenursinganswers.com)
  • however, a variable but measurable amount of AD pathologic changes exist in most cognitively intact elderly individuals who undergo autopsy, indicating that AD is a chronic disease with latent and prodromal stages and suggesting that individuals may have varying abilities to compensate, either biologically or functionally, for the presence of AD. (medscape.com)
  • Cerebrovascular Aβ deposits accompany functional and pathological changes in cerebral blood vessels (CAA-associated vasculopathies). (docksci.com)
  • Research on the signs, symptoms, and pathogenesis of WNV disease has greatly intensified in the past 5 years. (cdc.gov)
  • The myriad of symptoms described in basal ganglia pathologies seem to be determined by the maintenance of many of the physiological and behavioural properties of the cortical areas that they subserve, but also by the possible influence of reward on neurons within prefrontal-basal ganglia circuits. (units.it)
  • Emerging evidence from both in vivo and in vitro studies suggests that caffeine may reduce parkinsonian motor symptoms by antagonising the adenosine A 2A receptor, which is predominately expressed in the basal ganglia. (openneurologyjournal.com)
  • The rate of neurologic symptoms is higher in patients with a more severe respiratory disease status ( 1 ). (rsna.org)
  • 40. Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. (firebaseapp.com)
  • diseases specific to the peripheral nerves of the spinal cord (eg, spinal muscular atrophy, myelomeningocele) or to the muscles (eg, muscular dystrophies), although causing early motor abnormalities, are not considered cerebral palsy. (firebaseapp.com)
  • OBJECTIVES: Neonates with single ventricle congenital heart disease are at risk for structural cerebral abnormalities. (firebaseapp.com)
  • In general, they occur sporadically with rare familial incidence, and a few reports mention an association with other abnormalities like hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease), Wyburn-Mason syndrome, von Hippel-Lindau disease, and Sturge-Weber syndrome. (aapmr.org)
  • This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination. (cdc.gov)
  • However, the possibility of unilateral cerebrovascular events may be overlooked because of the lack of laterality of disease manifestations. (afpm.org.my)
  • Because her father had been diagnosed with MMD, the patient was referred to our hospital in 2011 for a close examination of her cerebrovascular system due to possible familial occurrence of MMD. (surgicalneurologyint.com)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • In conclusion, these characteristic clinical and pathologic findings confirm ACTA2 -related cerebrovascular disease as a new cerebrovascular disorder for which new therapeutic strategies need to be designed. (biomedcentral.com)
  • Huntington's disease (HD) is an adult onset inherited neurodegenerative disorder affecting both the striatum and cerebral cortex. (firebaseapp.com)
  • The pathology and pathogenesis of WNV disease have been described more completely than ever before. (cdc.gov)
  • We present the first integrated analysis of a severely compromised patient with the R179H mutation and define the arterial pathology of ACTA2 -related cerebrovascular disease. (biomedcentral.com)
  • As with many neurodegenerative diseases, both rare autosomal-dominant forms of AD and more common sporadic forms with genetic risk factors without causative mutations exist. (medscape.com)
  • Mutations can occur de novo and the disease has an autosomal dominant mode of transmission. (biomedcentral.com)
  • 1,3,11 Hereditary hemorrhagic telangiectasia, an autosomal-dominant disease, is the most common genetic cause of cerebral AVM and carries a 10-25% lifetime risk of developing a cerebral AVM. (aapmr.org)
  • These calcium deposits are visible only on medical imaging and typically occur in the basal ganglia, which are structures deep within the brain that help start and control movement of the body. (medlineplus.gov)
  • Although a detailed laboratory examination did not confirm the etiology, autoimmune disease was suspected to have precipitated this vascular lesion. (surgicalneurologyint.com)
  • Of these, sporadic amyloid β-protein (Aβ)-type CAA is most commonly found in older individuals and in patients with Alzheimer's disease (AD). (docksci.com)
  • Despite the multiple episodes of Bell's palsy recurrences, the patient did not suffer much neurological sequelae from the disease. (afpm.org.my)
  • Multiple sclerosis is a common, chronic demyelinating neurological disease primarily affecting young adults, with a prevalence of ~0.1% in the Caucasian population (Miller and Leary, 2007). (medscape.com)
  • 178 disease terms (MeSH) has been reported with GPX1 gene. (cdc.gov)
  • Neurosonology has become a worldwide appreciated clinical and scientific tool box devoted to the use of ultrasound techniques for the detection and investigation of the cerebrovascular system in health and disease. (neurosonology-bg.com)
  • Lupus nephritis (LN), the most important predictor of morbidity in SLE, develops in almost 30% of SLE patients at disease onset and in up to 50-60% within the first 10 years. (bvsalud.org)
  • ACTA2 mutations predispose to development of aortic aneurysms and early onset coronary and cerebrovascular disease. (biomedcentral.com)
  • Treatment of mild to moderate chorea in Huntington's disease, when other medicinal products are ineffective or not tolerated. (medicines.org.uk)
  • Systemic lupus erythematosus is a chronic autoimmune disease characterized by loss of tolerance against nuclear and cytoplasmic self-antigens, induction of immunity and tissue inflammation. (bvsalud.org)
  • Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved. (docksci.com)
  • Introduction Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition. (docksci.com)
  • On the other hand, ischemia/infarction/microangiopathy compatible with hypoxic-ischemic encephalopathy (HIE) were found on various brain areas including subcortical white matter (7/13), cerebral cortex, central semiovlae, basal ganglia, putamen, periventricular white matter, and cerebellum. (accjournal.org)
  • Based on arteriographic findings, a distinct cerebrovascular disease has been proposed for ACTA2 heterozygous patients carrying the R179H mutation. (biomedcentral.com)
  • Other causes include prevalence of progressive brain conditions, drug-induced Parkinsonism and cerebrovascular disease (Bonifati, 2014). (onlinenursinganswers.com)