A species of gram-negative bacteria that is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY). This organism can also be a cause of CAT-SCRATCH DISEASE in immunocompetent patients.
A genus of gram-negative bacteria characteristically appearing in chains of several segmenting organisms. It occurs in man and arthropod vectors and is found only in the Andes region of South America. This genus is the etiologic agent of human bartonellosis. The genus Rochalimaea, once considered a separate genus, has recently been combined with the genus Bartonella as a result of high levels of relatedness in 16S rRNA sequence data and DNA hybridization data.
Infections by the genus BARTONELLA. Bartonella bacilliformis can cause acute febrile anemia, designated Oroya fever, and a benign skin eruption, called verruga peruana. BARTONELLA QUINTANA causes TRENCH FEVER, while BARTONELLA HENSELAE is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY) and is also one of the causes of CAT-SCRATCH DISEASE in immunocompetent patients.
A self-limiting bacterial infection of the regional lymph nodes caused by AFIPIA felis, a gram-negative bacterium recently identified by the Centers for Disease Control and Prevention and by BARTONELLA HENSELAE. It usually arises one or more weeks following a feline scratch, with raised inflammatory nodules at the site of the scratch being the primary symptom.
A reactive vascular proliferation that is characterized by the multiple tumor-like lesions in skin, bone, brain, and other organs. Bacillary angiomatosis is caused by infection with gram-negative Bartonella bacilli (such as BARTONELLA HENSELAE), and is often seen in AIDS patients and other IMMUNOCOMPROMISED HOSTS.
A species of gram-negative bacteria in which man is the primary host and the human body louse, Pediculus humanus, the principal vector. It is the etiological agent of TRENCH FEVER.
Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
An intermittent fever characterized by intervals of chills, fever, and splenomegaly each of which may last as long as 40 hours. It is caused by BARTONELLA QUINTANA and transmitted by the human louse.
The type species of the genus BARTONELLA, a gram-negative bacteria found in humans. It is found in the mountain valleys of Peru, Ecuador, and Southwest Columbia where the sandfly (see PHLEBOTOMUS) vector is present. It causes OROYA FEVER and VERRUGA PERUANA.
An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.
A vascular disease of the LIVER characterized by the occurrence of multiple blood-filled CYSTS or cavities. The cysts are lined with ENDOTHELIAL CELLS; the cavities lined with hepatic parenchymal cells (HEPATOCYTES). Peliosis hepatis has been associated with use of anabolic steroids (ANABOLIC AGENTS) and certain drugs.
A family of small gram-negative bacteria whose organisms are parasites of erythrocytes in man and other vertebrates and the etiologic agents of several diseases.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
A genus of FLEAS in the family Pulicidae. It includes the cat flea (Ctenocephalides felis), one of the most common species on earth.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
An island of the West Indies. Its capital is St. George's. It was discovered in 1498 by Columbus who called it Concepcion. It was held at different times by the French and the British during the 18th century. The British suppressed a native uprising in 1795. It was an associate state of Great Britain 1967-74 but became an independent nation within the British Commonwealth in 1974. The original name referred to the Feast of the Immaculate Conception but it was later renamed for the Spanish kingdom of Granada. (From Webster's New Geographical Dictionary, 1988, p467 & Room, Brewer's Dictionary of Names, 1992, p219)
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.
Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.
Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.
Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.
Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.
A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labeled with fluorescein-conjugated anti-immunoglobulin antibody. (From Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
A tribe of gram-negative bacteria of the family RICKETTSIACEAE whose organisms are found in arthropods and are pathogenic for man and certain other vertebrate hosts.
Inflammation in which both the anterior and posterior segments of the uvea are involved and a specific focus is not apparent. It is often severe and extensive and a serious threat to vision. Causes include systemic diseases such as tuberculosis, sarcoidosis, and syphilis, as well as malignancies. The intermediate segment of the eye is not involved.
A neoplastic disease of cats frequently associated with feline leukemia virus infection.
A family of small, gram-negative organisms, often parasitic in humans and other animals, causing diseases that may be transmitted by invertebrate vectors.
Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers).
The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen.

Cat-scratch disease with paravertebral mass and osteomyelitis. (1/275)

The case of a 9-year-old girl with cat-scratch disease (CSD) complicated by development of a paravertebral mass and osteomyelitis is presented. Following multiple scratches and inguinal lymphadenopathy, she developed back pain, and imaging demonstrated a paravertebral mass with evidence of osteomyelitis involving vertebra T9. The diagnosis was made on the basis of detection of Bartonella henselae by use of molecular techniques on an aspirate from the vertebral column and supportive serology for infection with B. henselae. Eleven other cases of this unusual manifestation associated with CSD have been reported in the literature and are reviewed. The patient was treated with gentamicin, followed by rifampicin and trimethoprim-sulfamethoxazole, orally and made a favorable recovery over 7 months. This is comparable with other case reports, regardless of the choice of antibiotic therapy. CSD in immunocompetent hosts is not always self-limiting, and tissues beyond the lymph nodes can be involved.  (+info)

Detection of Bartonella henselae DNA by two different PCR assays and determination of the genotypes of strains involved in histologically defined cat scratch disease. (2/275)

Cat scratch disease (CSD) is a common cause of subacute regional lymphadenopathy, not only in children but also in adults. Serological and molecular studies demonstrated that Bartonella henselae is the etiologic agent in most cases of CSD. Amplification of B. henselae DNA in affected tissue and detection of antibodies to B. henselae are the two mainstays in the laboratory diagnosis of CSD. We designed a retrospective study and investigated formalin-fixed, paraffin-embedded lymph nodes from 60 patients (25 female, 35 male) with histologically suspected CSD by PCR amplification. The sensitivities of two different PCR assays were compared. The first primer pair amplified a 296-bp fragment of the 16S rRNA gene in 36 of the 60 samples, corresponding to a sensitivity of 60%. The second primer pair amplified a 414-bp fragment of the htrA gene in 26 of the 60 lymph nodes, corresponding to a sensitivity of 43.3%. Bartonella DNA could be detected in a total of 39 (65%) of the 60 lymph nodes investigated. However, histopathologic findings are typical but not specific for CSD and cannot be considered as a "gold standard" for diagnosis of CSD. The sensitivity of the PCR assays increased from 65 to 87% if two criteria (histology and serology) were used in combination for diagnosis of CSD. Two genotypes (I and II) of B. henselae are described as being involved in CSD. Genotype I was found in 23 (59%) and genotype II was found in 9 (23%) of the 39 PCR-positive lymph nodes. Seven (18%) lymph nodes were negative in both type-specific PCR assays. Thirty (50%) of our 60 patients were younger than 20 years old (15 were younger than 10 years), 20 (33%) were between 21 and 40 years old, and 10 (17%) patients were between 41 and 84 years old. Our data suggest that detection of Bartonella DNA in patients' samples might confirm the histologically suspected diagnosis of CSD.  (+info)

Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). (3/275)

Bartonella quintana and Bartonella henselae are fastidious gram-negative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. During a 5-year period, we received 2,043 samples for culture of Bartonella sp. We found Bartonella sp. to be the etiologic agent in 38 cases of endocarditis, 78 cases of cat scratch disease, 16 cases of bacteremia in homeless people, and 7 cases of bacillary angiomatosis. We correlated the results of positive cultures with the clinical form of the disease, type of sample, culture procedure, PCR-based genomic detection, and antibody determination. Seventy-two isolates of B. quintana and nine isolates of B. henselae from 43 patients were obtained. Sixty-three of the B. quintana isolates and two of the B. henselae isolates, obtained from patients with no prior antibiotic therapy, were stably subcultured. The sensitivity of culture was low when compared with that of PCR-based detection methods in valves of patients with endocarditis (44 and 81%, respectively), skin biopsy samples of patients with bacillary angiomatosis (43 and 100%, respectively), and lymph nodes of cat scratch disease (13 and 30%, respectively). Serological diagnosis was also more sensitive in cases of endocarditis (97%) and cat scratch disease (90%). Among endocarditis patients, the sensitivity of the shell vial culture assay was 28% when inoculated with blood samples and 44% when inoculated with valvular biopsy samples, and the sensitivity of both was significantly higher than that of culture on agar (5% for blood [P = 0.045] and 4% for valve biopsy samples [P < 0.0005]). The most efficient culture procedure was the subculture of blood culture broth into shell vials (sensitivity, 71%). For patients with endocarditis, previous antibiotic therapy significantly affected results of blood culture; no patient who had been administered antibiotics yielded a positive blood culture, whereas 80% of patients with no previous antibiotic therapy yielded positive blood cultures (P = 0.0006). Previous antibiotic therapy did not, however, prevent isolation of Bartonella sp. from cardiac valves but did prevent the establishment of strains, as none of the 15 isolates from treated patients could be successfully subcultured. For the diagnosis of B. quintana bacteremia in homeless people, the efficiency of systematic subculture of blood culture broth onto agar was higher than that of direct blood plating (respective sensitivities, 98 and 10% [P < 10(-7)]). Nevertheless, both procedures are complementary, since when used together their sensitivity reached 100%. All homeless people with positive blood cultures had negative serology. The isolation rate of B. henselae from PCR-positive lymph nodes, in patients with cat scratch disease, was significantly lower than that from valves of endocarditis patients and skin biopsy samples from bacillary angiomatosis patients (13 and 33%, respectively [P = 0.084]). In cases of bacillary angiomatosis for which an agent was identified to species level, the isolation rate of B. henselae was lower than the isolation rate of B. quintana (28 and 64%, respectively [P = 0.003]). If culture is to be considered an efficient tool for the diagnosis of several Bartonella-related diseases, methodologies need to be improved, notably for the recovery of B. henselae from lymph nodes of patients with cat scratch disease.  (+info)

Acute clinical disease in cats following infection with a pathogenic strain of Bartonella henselae (LSU16). (4/275)

Bartonella henselae is the causative agent of human cat scratch disease as well as several serious sequelae of infections, including bacillary angiomatosis and bacillary peliosis. Conflicting reports describe the pathogenesis of B. henselae in the cat. In this study, we characterized a strain of B. henselae termed LSU16. This strain was isolated on rabbit blood agar from a naturally infected 10-month-old female cat during a recurrent episode of bacteremia. The bacterial species was confirmed by PCR-restriction fragment length polymorphism analysis. Nine cats were infected intradermally with 5 x 10(7) CFU of LSU16, and clinical signs, antibody responses, and bacteremia were monitored. All nine cats developed raised, erythematous areas at the site of inoculation within 72 h postinoculation; the swelling peaked at 14 days postinfection and was not palpable by 28 days postinfection. Fever developed in all nine cats between 6 and 16 days postinfection and lasted for 1 to 8 days. Between 6 and 16 days postinfection, all nine cats experienced lethargy which persisted 5 to 18 days. Seven of nine cats were bacteremic by day 7, and all nine cats had become bacteremic by 14 days postinfection. Bacteremia peaked at 14 to 28 days postinfection in all cats. In six of the nine infected cats, bacterial numbers reached nondetectable levels during the 7th week postinfection; however, a single animal maintained bacteremia to 18 weeks postinfection. All nine cats developed strong antibody responses to B. henselae, as determined by Western blot analysis and enzyme-linked immunosorbent assay. Subsequently, three naive cats were injected intradermally with blood from cats infected with LSU16 from a pure culture, and five naive cats were injected with feces from fleas which had been feeding on cats infected with a pure culture of LSU16. These cats developed signs similar to those described in the previous experiment and were euthanized at 5 weeks postinfection. We conclude that B. henselae LSU16 is a virulent strain of B. henselae in cats and propose that the virulence of B. henselae in cats is strain dependent.  (+info)

Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from The Philippines. (5/275)

One hundred seven domestic cats from The Philippines were serologically tested to establish the prevalence of Bartonella infection. A subset of 31 of these cats also had whole blood collected to tentatively isolate Bartonella strains. Bartonella henselae and B. clarridgeiae were isolated from 19 (61%) of these cats. Bartonella henselae type I was isolated from 17 (89%) of the 19 culture-positive cats. Six cats (31%) were infected with B. clarridgeiae, of which four were coinfected with B. henselae. Sixty-eight percent (73 of 107) and 65% (70 of 107) of the cats had antibodies to B. henselae and B. clarridgeiae, respectively, detected by an immunofluorescence antibody (IFA) test at a titer > or = 1:64. When tested by enzyme immunoassay (EIA), 67 cats (62.6%) had antibodies to B. henselae and 71 cats (66.4%) had antibodies to B. clarridgeiae. Compared with the IFA test, the B. henselae EIA had a sensitivity of 90.4% and a specificity of 97%, with positive and negative predictive values of 98.5% and 82.5%, respectively. Similarly, the B. clarridgeiae EIA had a sensitivity of 97% and a specificity of 92% specificity, with positive and negative predictive values of 95.8% and 94.4%, respectively. The presence of antibodies to Bartonella was strongly associated with flea infestation. Domestic cats represent a large reservoir of Bartonella infection in the Philippines.  (+info)

Presumed ocular bartonellosis. (6/275)

BACKGROUND: The spectrum of diseases caused by Bartonella henselae continues to expand and ocular involvement during this infection is being diagnosed with increasing frequency. METHODS: The clinical features and visual prognosis for 13 patients with intraocular inflammatory disease and laboratory evidence of bartonellosis were investigated. There were nine patients with neuroretinitis and four with panuveitis with positive antibody titres against B henselae determined by an enzyme immunoassay (IgG exceeding 1:900 and/or IgM exceeding 1:250). RESULTS: Positive IgG levels were found for eight patients and positive IgM levels for five. Despite animal exposure of 10 patients, only two (IgG positive) cases had systemic symptoms consistent with the diagnosis of cat scratch disease. Pathological fluorescein leakage of the optic disc was observed in all affected eyes. At 6 months' follow up, 3/18 (17%) affected eyes had a visual acuity of less than 20/100, owing to optic disc atrophy and cystoid macular oedema. 12 patients (17 eyes) were treated with antibiotics; visual acuity improved two or more Snellen lines for 9/17 (53%) eyes. CONCLUSIONS: The possibility of B henselae infection should be considered in patients with neuroretinitis and panuveitis (especially in cases with associated optic nerve involvement) even in the absence of systemic symptoms typical for cat scratch disease.  (+info)

Identification of Bartonella-specific immunodominant antigens recognized by the feline humoral immune system. (7/275)

The seroreactivities of both naturally and experimentally infected cats to Bartonella henselae was examined. Serum samples collected weekly from nine cats experimentally infected with B. henselae LSU16 were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The magnitude and isotype of the antibody response were investigated by ELISA. Western blot analysis allowed the identification of at least 24 Bartonella-specific antigens recognized by the cats during infection. Antibody titers to specific antigens, as determined by Western blot analysis, ranged from 10 to 640 and varied among the different antibody-antigen interactions. Absorption of sera from an experimentally infected cat, using whole cells and cell lysates of various Bartonella species and other bacteria that commonly colonize cats, supported the identification of those Bartonella-specific antigens recognized by the experimentally infected cats. Furthermore, a number of possible species- and type-specific antigens were identified. Finally, sera obtained from cats at local animal shelters were screened for the presence of antibodies directed against the Bartonella-specific bands identified in the experimentally infected cats. A number of Bartonella-specific antigens have been identified to which strong antibody responses are generated in both experimentally and naturally infected cats, some of which may be useful in diagnosing species- and/or type-specific infections. In addition, the results from these experiments will lead to the development of monoclonal antibodies targeted against those genus-, species-, and type-specific antigens.  (+info)

Characterization of Bartonella henselae-specific immunity in BALB/c mice. (8/275)

BALB/c mice were inoculated with Bartonella henselae by both systemic and mucosal routes. Culture analysis of tissues from mice infected intraperitoneally with a high dose of B. henselae yielded positive results 24 hr after infection. However, culture analysis of blood taken between 6 hr and 7 days after infection from groups receiving live B. henselae were negative. Following intraperitoneal infection, B. henselae was detected by polymerase chain reaction in liver and mesenteric lymph nodes by 6 hr and up to 7 days after infection in liver, kidney and spleen tissue. Enzyme-linked immunosorbent assay (ELISA) of serum samples collected as early as 13 days after infection indicated humoral immune responses to B. henselae. Specific humoral responses remained through week 6. Analysis of faecal samples revealed induction of B. henselae-specific immunoglobulin A by day 28 after infection. In addition, B. henselae-specific cellular responses were indicated by a positive delayed-type hypersensitivity and a T helper 1 (Th1) (CD4+ T cell)-type cytokine response following in vitro stimulation of splenocytes. The significance and implications of these data in relation to B. henselae infections are discussed.  (+info)

Bartonella henselae is a zoonotic agent in which the domestic cat serves as the natural reservoir, and humans acquire potentially serious infections associated with this microorganism. The purpose of this research is to contribute to the understanding of the pathogenesis of B. henselae in the domestic cat using a molecular approach. Using sequence differences in a portion of the I 6S rRNA gene between B. henselae genotype I, and B. henselae genotype II, a nested polymerase chain reaction (nPCR) was designed and used to investigate various phases of feline bartonellosis. The nPCR detected 3.2 organisms per milliliter of blood which is below the detection limits of standard bacterial culture. Bartonella henselae LSU 16 genotype II, Bartonella henselae Baby genotype II, Bartonella henselae 87--66 genotype I, and Bartonella henselae Houston-1 genotype I were used in this study to infect cats. The PCR assay detected Bartonella DNA in 40 blood samples that were culture negative. The bacteremia as
Commonly abbreviated as CSD, Cat Scratch Disease is an infectious disease caused by the bacteria Bartonella henselae. As the name suggests, CSD is often caused by scratches and bites from cats that become infected. An indication of CSD is when the lymph nodes around the neck, heads, and sometimes the upper limbs show signs of swelling. Other symptoms of CSD may include fatigue, fever, headache, and a loss of appetite. In rare instances, complications from CSD may arise such as Parinauds oculolandular syndrome and bacillary angiomatosis. Cats do have the capacity to spread Bartonella henselae to humans. Kittens pose a greater risk than cats and pass the bacterium onto their owners more often than adult cats. At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. Cats who are carriers display no symptoms and will not act sickly. It is impossible to tell whether or not a cat can spread the disease to their owner.. Individuals with weak ...
VIEIRA-DAMIANI, Gislaine et al. Bartonella henselae infection induces a persistent mechanical hypersensitivity in mice. Rev. Inst. Med. trop. S. Paulo [online]. 2020, vol.62, e79. Epub 30-Out-2020. ISSN 1678-9946. https://doi.org/10.1590/s1678-9946202062079.. Bartonella spp. are re-emerging and neglected bacterial pathogens. The natural reservoirs for several species of this genus are domestic animals such as cats and dogs, the most common pets in the USA and Brazil. Some cat studies suggest that the infection is more prevalent in tropical and poverty-stricken areas. These bacteria were associated with a wide spectrum of clinical manifestations: fever of unknown origin, endocarditis, angiomatosis, chronic lymphadenopathy, hepatitis, fatigue, paresthesia and pain. Our group has already demonstrated that B. henselae -infected sickle cell disease mice present with hyperalgesia. We hypothesized that even immunocompetent mice infected by B. henselae would show an increased and persistent mechanical ...
What is cat scratch disease (CSD)?. Cat Scratch Disease (CSD) is a bacterial infection caused by Bartonella henselae. It is transmitted to cats by flea droppings in a cats fur or claws. The bacteria spreads to people when an infected cat bites or scratches, or licks someones open wound. Young children and people with weak immune systems are the most likely to get CSD. Ticks may also spread Bartonella henselae to cats, but it is not clearly documented that ticks can spread CSD to people.. Does my cat carry this disease?. Not every cat or kitten will carry Bartonella henselae. The Centers for Disease Control and Prevention (CDC) estimates that about 40% of cats carry the bacteria at some time in their lives. Cats that carry this disease do not show any signs of illness, so you cannot tell which cats can spread the disease to you. Kittens and feral cats are the most likely to spread the disease because they are more likely to bite or scratch.. What are the symptoms of CSD?. The symptoms of CSD ...
It is reported that up to 95% of patients with Cat Scratch Disease present antibodies against Bartonella henselae antigens. Through a type IV secretory system, B. henselae proteins are transported into the host cells. The encoding gene of outer membrane protein p26 has significant nucleotide identity with orthologs in Brucella spp., Bartonella spp., and several plant-associated bacteria ...
Bacteria of the genus Bartonella are fastidious, facultative intracellular bacilli, belonging to the alpha-2 subgroup of Proteobacteria. Bartonella henselae is the causative agent of cat-scratch disease (CSD) and is also involved in other clinical situations such as endocarditis, bacillary angiomatosis (BA) and peliosis hepatitis (PH) in immunocompromised patients (1). Interestingly, erythromycin has become the drug of first choice and has been successfully used to treat many patients with BA (8) and PH (14). However, when the treatment duration is less than 15 days, relapses after antibiotic withdrawal are common, and therefore treatment should be given for 3 to 4 months (8). Macrolide compounds inhibit protein synthesis by binding to domains II and V of 23S rRNA (7). The first mechanism of macrolide resistance described was due to posttranscriptional modifications of the 23S rRNA by the adenine-N 6-methyltransferase. Modification of the ribosomal target confers cross-resistance to macrolides ...
B. henselae infection initiates after trauma to the skin, suggesting that adherence to host cells may be mediated by specific interactions between B. henselae surface proteins such as Pap31 and components of the host ECM such as Fn and Hep. Pap31 was previously shown to be involved in acquisition of heme and thus may be an important virulence factor for B. henselae (8, 53). Because heme receptor molecules are surface exposed, we undertook to determine if Pap31 had another virulence function as an adhesin to ECM. We have expressed and purified B. henselae Pap31 with high yield and purity and demonstrated its immunogenicity. We also demonstrated that Pap31 acts as a potential ligand for Fn and Hep, indicating its broad-range binding ability. Recognition of anti-Pap31 antibodies in rabbits or mice vaccinated with live B. henselae or purified Pap31, respectively, indicated that the protein is expressed in vivo and contributes to the humoral immune response in the host defense against B. henselae. ...
Infection of humans with the zoonotic bacterium Bartonella henselae (Bh) can result in a range of clinical symptoms and disease including lymphadenopathy associ...
Gentaur molecular products has all kinds of products like :search , Fuller \ Bartonella henselae 12_well Substrate Slide Species Human_Canine_Equine \ BH-12 for more molecular products just contact us
The potential role of ticks as vectors of Bartonella species has recently been suggested. In this study, we investigated the presence of Bartonella species in 271 ticks removed from humans in Belluno Province, Italy. By using primers derived from the ...
One of the most striking examples of how Lyme disease co-infections can wreak havoc on the extracellular matrix and connective tissues comes from a 2018 study that looked at the effects of Bartonella infection, rheumatological symptoms and associated joint hypermobility (8). The case study publication concerned a female veterinarian who displayed the clinical symptoms of EDS (Ehlers-Danlos Syndrome), Type 3. Type 3 EDS is considered to be the most severe form of EDS, chiefly affecting the vascular system, and leading to a significantly reduced life expectancy. The patient was identified as having a Beighton hypermobility score of 7/9.. The patient was found to have Bartonella koehlerae and Bartonella henselae infections. Bartonella bacterial infections have a notable and destructive effect on the vasculature and endothelial functions. The patient was treated for bartonella using the longterm use of antibiotics. The treatment resulted in the resolution of the patients symptoms, and notably the ...
Cat scratch disease, a mild flu-like infection, with swollen lymph nodes (lymphadenitis) and mild fever of short duration, due to cat scratches, especially from kittens. There is usually a little bump (a papule) which may be pus-filled (a pustule) at the site of the scratch. The infection is self-limited and usually goes away by itself in a few weeks. It can also be treated with antibiotics, but it can cause a severe inflammation called bacillary angiomatosis in patients with weakened immune systems. A cat carrying the microbe does not show symptoms and it is not necessary to get rid of it. If someone in the household is at high risk, a test to detect the infection can be done and the cat can be treated. The disease is caused by a bacterium called Rochalimaea henselae, eventually reclassified as Bartonella henselae, named for Diane Hensel, a microbiologist. The disease has also been called regional lymphadenitis. ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Principal Investigator:MARUYAMA Soichi, Project Period (FY):1998 - 1999, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Applied veterinary science
Enseleit, F; Wyss, C A; van der Loo, B; Grünenfelder, J; Oechslin, E N; Jenni, R (2009). Isolated cleft in the posterior mitral valve leaflet: a congenital form of mitral regurgitation. Clinical Cardiology, 32(10):553-560.. Kovacevic-Preradovic, T; Jenni, R; Oechslin, E N; Noll, G; Seifert, Burkhardt; Attenhofer Jost, C H (2009). Isolated left ventricular noncompaction as a cause for heart failure and heart transplantation: a single center experience. Cardiology, 112(2):158-164.. Luthi, P; Zuber, M; Ritter, M; Oechslin, E N; Jenni, R; Seifert, B; Baldesberger, S; Attenhofer Jost, C H (2008). Echocardiographic findings in former professional cyclists after long-term deconditioning of more than 30 years. European Journal of Echocardigraphy, 9(2):261-267.. Fischer, A H; van der Loo, B; Shär, G M; Zbinden, R; Duru, F; Brunckhorst, C; Rousson, V; Delacrétazy, E; Stuber, T; Oechslin, E N; Follath, F; Jenni, R (2008). Serological evidence for the association of Bartonella henselae infection with ...
Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) has been cited in 4 publications. Find out more about the references
Abcam provides specific protocols for Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) : Immunohistochemistry protocols
This disease is caused by an infection with the organism Bartonella henselae that occurs following being scratched by a cat. Includes its epidemiology, presentation, differential diagnosis, investigation and management. ...
Worldwide distribution. Transmission from cat to human mainly occurs by cat scratch or bite, possibly by flea bite.. Domestic cats are the main reservoir of Bartonella henselae. Epidemiological studies showed bacteria prevalence ranging from 15% to 55% in many countries, including Europe, United States, Asia, Australia and Africa.. No direct transmission from cat to cat in a flea-free environment and no vertical transmission from infected queens to their kittens have been observed. ...
The genus Bartonella contains Gram-negative arthropod-borne bacteria that are found in many small animal reservoirs and are capable of causing human disease. Bacteria utilize a general stress response system to combat stresses from their surrounding environments. In α-proteobacteria, the general stress response system uses an alternate σ factor as the main regulator and incorporates it with a two-component system into a unique system. Our study identifies the general stress response system in the α-proteobacterium, Bartonella henselae, where the gene synteny is conserved and both the PhyR and alternate σ factor have similar sequence and domain structures with other α-proteobacteria. Furthermore, we showed that the general stress response genes are up-regulated under conditions that mimic the cat flea vector. We also showed that both RpoE and PhyR positively regulate this system and that RpoE also affects transcription of genes encoding heme-binding proteins and the BadA adhesin. Finally, we also
Buy viagra online canadian - It is more common in immunocompromised bite victims bartonella henselae is the viagra buy online canadian sympathetic pathway to segments t l gupta r k a the metanephric kidney curr top dev biol a kume t deng k and sandford r cardiovascular skeletal and dental injuries the. All tablets dosages available today. Read on to learn more about our online pharmacy, how to get started, and the many advantages of purchasing Viagra online from …. 100% Satisfaction Guaranteed! These physical symptoms are smiley faces all caps Generic Viagra Online comes into strength of 100mg. Free shipping, quality, privacy, secure. Lowest Prices. Tension whether of muscle Blood Donation Cialis buy viagra online canada tension indispensable latterly 4 component an. Health Care specializes in registered nurses, physicians, doctors, hospital management jobs as well as other employment in healthcare. 26 urinary retention definition10 the state in which one lives as how the desired groups or ...
1. the most important clues for Dx. ① Hx. of contact with animals. (esp. kittens). ② identification of an inoculation skin or ocular lesion. 2. regional lymphadenopathy. (cat contact후 몇주후에 발생됨). : CSD suggest. → 특히 primary inoculation papule혹은 pustule이 cat scratch후 생겼다면. 3. criteria for a definitive diagnosis. ① contact with a cat & the presence of a scratch or primary lesion of the dermis, eye, or a mucous membrane. ② a positive skin test for CSD or. positive serologic test for B. henselae antibody. ③ negative serologies,. including purified protein derivative skin tests & culures of aspirated pus or LN performed for other causes of lymphadenopathy. ④ characteristic pathologic features in biopsy specimen of skin, LN or ocular granuloma. : clinical practice. → Dx은 4가지 criteria중 3가지 (+)인 경우 4. confirm in atypical cases. : fourfold rise in titer for B. henselae or by demonstrating small, pleomorphic bacilli. in Warthin-Starry ...
...HOUSTON-(May 23 2011)-People with diabetes have a three to five times...Results of the study which included 233 patients with TB who live in ... With the increase in diabetes patients in TB-endemic areas our findi...Study results found 25 percent of TB cases were attributed to the pres...,UTHealth,researchers,find,diabetics,at,higher,risk,of,tuberculosis,infection,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
When the drug screen is performed in the laboratory, the drug screen results take 24 to 72 business hours after specimen collection. If the drug screen is non-negative, the result and specimen will then need to be confirmed. Confirmation takes an additional 48 to 72 business hours after the screen is completed.. ...
Centrum Badań DNA to nowoczesny medyczny ośrodek naukowo-diagnostyczny, oferuje badania genetyczne i diagnostykę zakażeń w oparciu o najnowsze technologie diagnostyczne
Centrum Badań DNA to nowoczesny medyczny ośrodek naukowo-diagnostyczny, oferuje badania genetyczne i diagnostykę zakażeń w oparciu o najnowsze technologie diagnostyczne
Śródbłonkowe działanie aldosteronu implikacje terapeutyczne płynące z badań podstawowych i klinicznych Endothelial action of aldosteron therapeutic implications from basic and clinical research. Drelicharz
The papers presented in Volume I constitute a collection of contributions, both of a foundational and applied type, by both well-known experts and young researchers in various fields of broadly...
Ilikuwa ni sherishori pale mchungaji wa kanisa la calvari la urafiki ambae aliamua kumtambulisha kifaa chake kipya baada ya kufiwa na mkewe miezi...
Autorskie projekty badawcze z zakresu neurologii, ortopedii, toksykologii, chirurgia doświadczalnej, onkologii, badań metabolicznych i behawioralnych (AnyMAZE, basen Morrisa, klatki strachu, Intellicage ...
EVERESTVIT - Technologie Badań Wizualnych, urządzenia do testów niedestrukcyjnych dla przemysłu lotniczego, energetycznego, inspekcja, sprawdzanie stanu technicznego, system endoskopii przemysłowej, endoskopy, fiberoskopy, boroskopy, endoskopy przemysłowe
Suplement do dyplomu Doświadczenia Wyższej Szkoły Humanistyczno-Ekonomicznej w Łodzi Renata Figlewicz Centrum Badań i Rozwoju Kształcenia Wyższa Szkoła Humanistyczno-Ekonomiczna w liczbach 2 wydziały 10
Cat scratch disease is also known as cat scratch fever. This disease strikes people who are infected by the Bartonella henselae bacteria. In almost all cases, cat scratch disease occurs when the person was scratched or bitten by his cat. The cat itself does not catch cat scratch disease. It is just a carrier. Now, before you panic and send your cat to the pound, the National Center for Infectious Diseases (CDC) estimates that 40% of all cats carry this disease at some time in their lives. Considering how many cat owners exist in the world, clearly, this disease is not very infectious or dangerous.. But how do you know whether you were infected by cat scratch disease? The first thing you want to look at is the place your cat bit or scratched you. Is the wound infected? (Note: If you cannot find the wound, then you do not have cat scratch disease.) Then you want to check your lymph nodes. Are the nodes around your head, neck and upper limbs swollen? Do you also have fever, headache, fatigue, and a ...
IIIChris Hani Baragwanth Hospital, Bertsham, South Africa. Correspondence to. Bartonella is a genus of opportunistic, Gram-negative bacilli transmitted from animals to human hosts. Bartonellae are newly emerging pathogens that can cause a variety of clinical manifestations in both immunocompromised and healthy persons.. The aims were to determine the IgG and IgM seroprevalences of Bartonella henselae and Bartonella quintana in immunocompromised and immunocompetent individuals using an immunofluorescence assay (IFA).. A total of 382 HIV-positive outpatients of the Chris Hani Baragwanth HIV-clinic, 382 retrospective residual samples from HIV-negative antenatal patients, and 42 clinically healthy volunteers were tested using a commercially available IFA kit to determine the prevalence of IgG and IgM antibodies to B. henselae and B. quintana.. The IgM and IgG seroprevalences for the HIV-positive patients were 14% (53/382) and 32% (121/382), respectively, compared to 18% for both IgM (62/342) and IgG ...
IIIChris Hani Baragwanth Hospital, Bertsham, South Africa. Correspondence to. Bartonella is a genus of opportunistic, Gram-negative bacilli transmitted from animals to human hosts. Bartonellae are newly emerging pathogens that can cause a variety of clinical manifestations in both immunocompromised and healthy persons.. The aims were to determine the IgG and IgM seroprevalences of Bartonella henselae and Bartonella quintana in immunocompromised and immunocompetent individuals using an immunofluorescence assay (IFA).. A total of 382 HIV-positive outpatients of the Chris Hani Baragwanth HIV-clinic, 382 retrospective residual samples from HIV-negative antenatal patients, and 42 clinically healthy volunteers were tested using a commercially available IFA kit to determine the prevalence of IgG and IgM antibodies to B. henselae and B. quintana.. The IgM and IgG seroprevalences for the HIV-positive patients were 14% (53/382) and 32% (121/382), respectively, compared to 18% for both IgM (62/342) and IgG ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin. Rubbing the eyes after petting a cats fur can also spread cat scratch disease. Young kittens younger than 1 year of age are more likely to scratch, increasing the likelihood of infection.. ...
Cat scratch disease (CSD), due to Bartonella henselae, is a self-limited chronic lymphadenopathy. A previously healthy 22-year-old woman presented with a palpable painful swelling in the right submandibular region accompanied by enlarged cervical lymph nodes. A diagnosis of B. henselae infection was made according to her personal history that divulged frequent contacts with cats and to a high titre of immunoglobulin G (IgG) and IgM antibodies for this agent. The patient improved within 1 month without the requirement of antibiotic treatment or surgery. The CSD should always be included in the differential diagnosis of all equivocal masses in the neck, especially in young individuals. In addition, it is important that a meticulous personal history is obtained. ...
The diagnostic value of the detection of immunoglobulin G (IgG) and IgM by Bartonella henselae-based indirect fluorescence assay (IFA) and enzyme-linked immunoassay (EIA) for the diagnosis of cat scratch disease (CSD) was evaluated. The IFA was performed either with B. henselae that was cocultivated for a few hours with Vero cells or with noncocultivated B. henselae as the antigen. Additionally, the performance of a Bartonella PCR hybridization assay based on the 16S rRNA gene was determined and compared with those of the serologic assays. The study group consisted of 45 patients suspected of suffering from CSD by fulfilling one or more of the classical criteria. The specificities of the immunoassays were set at , or = 95% by analysis of sera from 60 healthy blood donors. It is shown that the sensitivities of the IgG assays are very low (40.9% for the IFA with noncocultivated B. henselae as antigen) and that those of the IgM assays are higher (71.4% for the EIA) for patients who fulfilled two or ...
Cat scratch disease, commonly called cat scratch fever, is an infection caused by Bartonella henselae, a bacterium carried in the saliva of infected cats. According to the KidsHealth website, ...
The currently accepted model explaining the infection cycle holds that the transmitting vectors are blood-sucking arthropods and the reservoir hosts are mammals. Immediately after infection, the bacteria colonize a primary niche, the endothelial cells. Every five days, some of the Bartonella bacteria in the endothelial cells are released into the blood stream, where they infect erythrocytes. The bacteria then invade a phagosomal membrane inside the erythrocytes, where they multiply until they reach a critical population density. At this point, they simply wait until they are taken up with the erythrocytes by a blood-sucking arthropod. Though some studies have found no definitive evidence of transmission by a tick to a vertebrate host, [7][8] Bartonella species are well-known to be transmissible to both animals and humans through various other vectors, such as fleas, lice, and sand flies.[9] Recent studies have shown a strong correlation between tick exposure and bartonellosis,[9][10] including ...
Kittens can be diagnosed as cat scratch disease carriers through a simple blood test, and positive kittens can be treated successfully with antibiotics. Because this disease can come back, however, this is not a silver bullet for preventing cat scratch disease. Declawing kittens at an early age is the best way to prevent infection. You should be aware of the ramifications to the cat before declawing it, however. Not only can it be dangerous for the cat to go outside, it can also be psychologically traumatic and cause unexpected complications like arthritis ...
Case Reports in Pediatrics is a peer-reviewed, Open Access journal that publishes case reports related to pediatric subspecialities, such as adolescent medicine, cardiology, critical care, dentistry, developmental and behavioral medicine, endocrinology, gastroenterology, genetics, haematology and oncology, neo- and perinatology, nephrology, neurology, psychology, pulmonology, rheumatology, and surgery.
Cat-scratch disease, also called bartonellosis, is by far the most common zoonotic disease associated with cats. Cat-scratch disease can occur when a person is bitten or scratched by an infected cat. Fleas may also play a role in the transmission of infection. People with cat-scratch disease usually have swollen lymph nodes, especially around the head, neck, and upper limbs. They may also experience fever, headache, sore muscles and joints, fatigue, and poor appetite. Some healthy cats are continuously or intermittently infected with cat-scratch disease bacteria. Avoiding scratches and bites, controlling fleas, and keeping cats indoors all reduce the risk of cat-scratch disease.. Fleas are the most common external parasite of cats. While fleas cannot thrive on humans, their bites can cause itching and inflammation. Fleas may also serve as vectors for cat-scratch and other zoonotic diseases. Flea-infested cats may become infected with tapeworms from fleas ingested while grooming. Children can ...
Cat scratch fever is a cat scratch disease that is is caused by bacteria called Bartonella henselea with symptoms that include high fever, anorexia, weakness, and badly swollen lymph nodes.
English , R. Cat-scratch disease. Pediatr Rev . vol. 27. 2006. pp. 123-8. (An in-depth review of the clinical features of CSD, including a nice discussion of the etiology and epidemiology of the disease. Also highlights the features of atypical disease in immunocompetent and immunocompromised hosts.) Reynolds , MG, Holman , RC, Curns , AT, OReilly , M, McQuiston , JH, Steiner , CA. Epidemiology of cat-scratch disease hospitalizations among children in the United States. Pediatr Infect Dis J . vol. 24. 2005. pp. 700-4. (This analysis of a national inpatient database examined the CSD-associated hospitalization rate among children for a specific year. The authors found that despite the increasing incidence of cat ownership from previous years, the overall hospitalization rate for CSD did not increase. They also found that early diagnosis by serologic testing obviated the need for unnecessary intervention.) Bass , JW, Cary Freitas , BC, Freitas , AD. Prospective randomized double blind ...
I dont have any scratches that are not healed or I havent had any that were infected at all. I always clean a scratch even a minor scratch as soon as it happens but previously working as a nurse noticed these symptoms as cat scratch disease although I dont have an infected scratch! Anyways with my lymphnodes being swollen not only under my arm but on my back and the inside of my upper leg I know I have some kind of infection! I am getting an antibiotic shot this afternoon and RX for antibiotics and taking BB to have her tested I was informed by the vet that if she test positive for it they can give her antibiotics to kill the bacteria even though she just had three antibiotic shots for her operation! This is crazy I never knew a cat scratch could be so dangerous . I am so sorry to all of you who have lost loved ones to this it just seems like such a minor problem and maybe that is why people dont think of it as urgent of life threatning! Thanks for all of your responses ...
Lymphoreticulosis Symptoms. EVERYTHING, THAT YOU WANTED TO KNOW ABOUT CATSCRATCH DISEASE (lymphoreticulosis), lymphoreticulosis SYMPTOMS. EFFECTIVE TREATMENT OF CAT-SCRATCH DISEASE. http://www.biofon.ru/eng/treat/catalog/lim.shtml Extractions: Cat-scratch disease (benign lymphoreticulosis) Â- infectious disease associated with a history of scratches, bites from or close contact with a cat. The infecting agent is Bartonella henselae a tiny bacillus of familia Chlamydiae. The host and the source of infection are cats, with the infection agent being a normal part of their mouth flora. Person-to-person transmission of the disease has not been shown. The infection enters through skin wounds causing inflammation. Carried by lymph the infection reaches the nearest lymph node causing its inflammation too. Further the infection spreads with the bloodstream over the system. After convalescence the body develops persistent immunity to the disease. Treating cat-scratch disease (lymphoreticulosis). Symptoms ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. Research suggests a cat may get these bacteria from fleas. The bacteria are passed from an infected cat to a human after the cat licks an open wound or bites or scratches human skin hard enough to break the surface of the skin. Kittens younger than one year of age are more likely to scratch, increasing the likelihood of infection. ...
Before DNA was extracted from the samples, 10 μL of blood was diluted in 190 µL of phosphate-buffered saline. DNA was automatically extracted by using a BioRobot Symphony Workstation and MagAttract DNA Blood M96 Kit (QIAGEN, Valencia, CA, USA). Bartonella DNA was amplified by using conventional Bartonella genus PCR primers targeting the 16S-23S intergenic spacer region: oligonucleotides, 425s (5′-CCG GGG AAG GTT TTC CGG TTT ATCC-3′) and 1,000as (5′-CTG AGC TAC GGC CCC TAA ATC AGG-3′). Amplification was performed in a 25-μL reaction, as described (3). All PCR reactions were analyzed by 2% agarose gel electrophoresis. Amplicons were sequenced to identify the Bartonella sp. and intergenic spacer region genotype. To compare sequences with those in GenBank, we identified bacterial species and genotypes by using Blast version 2.0 (http://blast.ncbi.nlm.nih.gov/Blast.cgi). DNA extraction and PCR-negative controls remained negative throughout the study.. Results are summarized in the Table. ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin.
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin.
Cat-scratch disease is an infection you can get after a cat scratches, bites, or licks you. Its caused by bacteria in cat saliva. Its usually not severe.
Cat-scratch disease is seasonal in the United States and Japan; but no data are available from Europe. To assess the seasonality of the disease in France, we analyzed lymph node biopsy specimens collected during 1999-2009. Most (87.5%) cases occurred during September-April and peaked in December.
Cats who are infected with cat scratch disease generally dont show any symptoms, but several illnesses seem to be correlated with infection.
Your mothers warning that a cats scratch could make you ill isnt just a tale concocted to discriminate against cats. Cat scratch fever is an actual disease that cats can contract and pass on through bites and scratches. What Mom may not have told you is that dogs can catch the disease, too, making it ...
Addresses: Andersson SGE, Uppsala Univ, Evolutionary Biol Ctr, Dept Mol Evolut, S-75236 Uppsala, Sweden. Uppsala Univ, Evolutionary Biol Ctr, Dept Mol Evolut, S-75236 Uppsala, Sweden. Univ Basel, Bioctr, Dept Mol Microbiol, CH-4056 Basel, Switzerland.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14 ...
These Pathogen Safety Data Sheets, regulated under Workplace Hazardous Materials Information System (WHMIS) legislation, are produced for personnel working in the life sciences as quick safety reference material relating to infectious micro-organisms.
Bartonella species can be isolated (with difficulty) from blood, using ethylenediaminetetraacetic acid (EDTA) tubes. The organisms have been isolated from tissue in only a few laboratories because of the fastidious nature of Bartonella.2 Polymerase chain reaction methods have been developed for identification and speciation of Bartonella but are not widely available.. Preventing Exposure. HIV-infected patients, specifically those who are severely immunocompromised (CD4 counts ,100 cells/mm3), are at high risk of severe disease when infected by B. quintana and B. henselae. The major risk factors for acquisition of B. henselae are contact with cats infested with fleas and receiving cat scratches. Immunocompromised individuals should consider the potential risks of cat ownership (AIII). Patients who want cats should acquire animals that are older than age 1 year and in good health (BII). Cats should be acquired from a known environment, have a documented health history, and be free of fleas. Stray ...
Cat scratch fever: Find the most comprehensive real-world symptom and treatment data on cat scratch fever at PatientsLikeMe. 15 patients with cat scratch fever experience fatigue, depressed mood, pain, anxious mood, and insomnia and use Amphetamine-Dextroamphetamine, Heating Pad-Hot Packs, Ibuprofen, and Massage Therapy to treat their cat scratch fever and its symptoms.
Bartonella species are members of the alpha-2 subgroup of the class Alphaproteobacteria, within the Rhizobiales order. There are now more than 22 species or subspecies described, and DNA sequences from numerous other species or strains have been deposited in GenBank. Warthin-Starry silver stain is recommended for microscopic detection of Bartonella organisms in fixed tissue sections but is not highly specific and is insensitive, even with lymph node biopsy samples from cat scratch disease (CSD) patients. In contrast, even when isolation of the infecting species is not possible, PCR amplification of internal transcribed spacer (ITS) DNA directly from diagnostic samples and/or from enrichment cultures followed by nucleic acid sequencing is an invaluable tool for primary identification at the species, subspecies, and genotype levels. The first serologic test for CSD was an immunofluorescence antibody assay (IFA) based on B. henselae bacilli that were cocultivated with Vero cells to inhibit
Cat-scratch disease (CSD) is a common and usually harmless infectious disease induced by the bacterium Bartonella henselae. It really is most commonly within children carrying out a scuff or bite from a feline within about one or two weeks.. see more at wikipedia. ...
DIAGNOSIS. Blood culture or fluid aspirated from the joints has the characteristic causative organism.. Animal inoculation: Spirillium minus can be demonstrated.. Blood picture - the disease is accompanied by leucocytosis and sometimes eosinophilia.. TREATMENT. Penicillin is an effective antibiotic for treatment of rat bite fever.. Cauterization of the wound by nitric acid may prevent spread of the disease when this is applied early after the bite.. CAT SCRATCH DISEASE. Cat scratch disease is caused by Gram-negative rods, which are part of the normal bacterial flora of cats, dogs and some other animals.. Most of the patients are children playing with cats, dogs that are a vector for the organism. Infection reaches the skin through traumatization of the skin by the cat scratch or by cat biting.. General manifestations. Fever, malaise and anorexia are not uncommon following the cat scratch. Central nervous system involvement. Purpura, thrombocytopenia and eye involvement are rare complications of ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrións disease, caused by B. bacilliformis.
As pet owners we seldom think about how our cat or dogs illness might negatively impact us beyond that of the regular inconvenience of visits to the vets, medical bills, and the cost of prescription drugs, etc. Most illnesses and common ailments that assail pets are non-transferable to humans, leaving us little reason to be concerned for our own welfare. However, though many people are not aware of it, there do exist certain diseases and bacteria which can be passed from a dog or cat to their human owner. Here are some of the illnesses to watch out for.. Cat Scratch Disease: Though the name of the disease sounds nonthreatening and trivial, it is an unpleasant experience to suffer from Cat Scratch Disease. Bacteria can be passed from the cats saliva (if he bites someone) or through this claws (by scratching). The victim would then suffer from fevers, headaches, lethargy, and swollen lymph nodes anywhere from a week to two weeks after the incident. The good news is, only about 40% of cats carry ...
What are the symptoms?. This is not a particularly serious or dangerous disease. It shows up in the form of enlargement of the lymph nodes. Lymph nodes are little glands that are a part of your immune system, and they are located in your armpit, groin, neck, and chest. When you get it, they work overtime and can start to swell. This lasts for about a month or so, and they may drain pus. Other symptoms include fevers, lethargy, headaches, and loss of appetite. What is the treatment?. Usually your doctor will just tell you to wait it out. The immune system will heal it on its own within three to six weeks in the vast majority of cases. If the person shows more severe symptoms, the doctor may want to use antibiotics to speed it up. There isnt a cure that will instantly make it go away.. Do I need to get rid of my cat if I get sick?. No. First of all, even most people who get scratched dont get it. Second, this is not a disease that you get multiple times. No one has ever been seen catching it ...
Psychiatry healthcare professionals gain a thorough knowledge base of psychiatric disorder information to offer the best patient care. Get our FREE app now.
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common medical conditions in daily practice.
How to Deal With a Cat Scratch. Cats can be playful, quirky, or occasionally aggressive. If you spend time around cats, its quite possible that you will suffer from a cat scratch at some point. Cats have sharp claws that they use to...
Cats can be cute - but they bring home more than mice. Scratches and bites can cause infections, from cat-scratch disease to MRSA bacteria to rabies.
To identify potential vaccine candidates against Ixodes ricinus and tick-borne pathogen transmission, we have previously sequenced the salivary gland transcriptomes of female ticks infected or not with Bartonella henselae. The hypothesized potential of both IrSPI (I. ricinus serine protease inhibitor) and IrLip1 (I. ricinus lipocalin 1) as protective antigens decreasing tick feeding and/or the transmission of tick-borne pathogens was based on their presumed involvement in dampening the host immune response to tick feeding. Vaccine endpoints included tick larval and nymphal mortality, feeding, and molting in mice and sheep. Whether the antigens were administered individually or in combination, the vaccination of mice or sheep elicited a potent antigen-specific antibody response. However, and contrary to our expectations, vaccination failed to afford protection against the infestation of mice and sheep by I. ricinus nymphs and larvae, respectively. Rather, vaccination with IrSPI and IrLip1 ...
Keep scratches clean, dry and bacteria-free to make sure they are only fleeting marks on your skin. Apple Footer. Paint a deep-looking scratch or a scratch that appears like an animal scrape. a Along with scratches, people also experience mysterious bite marks and inexplicable bruising. Chill OP, in time the entire face will get scratched and the finish will dull. Why skin gets inflamed when [â ¦] They seem to appear at times in our lives when temptation is near or when weâ re facing a big decision. Ask a question. Apply a small amount of 3µ paste to the scratch, working it in a firm circular motion with the cloth. The symptoms of cat-scratch disease can manifest about three to 14 days after an infected cat bites or scratches a person hard enough to break the skin, according to the Centers for Disease Control and Prevention. After a few minutes, you should start to see the scratch disappearing. I used to get these daily. And when forensics teams fâ ¦ Toothless the moggy attacked raider ...
Enlarged Spleen In Dogs found in: Dog Hemangiosarcoma, Ehrlichia Infection, Dog Malignant Histiocytoma, Dog Oral Squamous Cell Carcinoma, Cat Bartonella and Cat Scratch Disease, …does however, serve an important role..
Cat Scratch Fever Antibodies, IgM,ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories client,medicine,medical supply,medical supplies,medical product
Pantera Cat Scratch Fever lyrics & video : Im high! Well, I dont know where they come from, but they sure do come I hope theyre comin for me And I dont know how they do it,...
Misheard Lyrics, performed by Cat Scratch Fever. Misheard lyrics (also known as mondegreens) are instances of when a song lyric cant be understood, and the mind substitues a new word for you.
The cat scratch disease (CSD) skin test was once used to help diagnose CSD. The test is no longer used today. There are better methods available to diagnose CSD, such as antibody detection by the EIA test or bacteria detection by a PCR (polymerase chain reaction) test.
Her doctors couldnt figure out what was wrong. After some prodding, they told her father that Alexus had cat-scratch disease. Amadeo Rodriguez pushed back on that diagnosis - the family didnt have cats, and there had been no time in the preceding weeks when Alexus could have been scratched by one.. He was skeptical, but he let it go.. The following Monday, he arrived at work and promptly told his supervisor, You know what? Im gonna go. Somethings wrong, and I just have a gut feeling that somethings wrong.. That day, Armadeo Rodriguez pushed doctors for a biopsy. Then, on Wednesday, July 11, 2012, he got the phone call. Alexus had stage four Burkitts lymphoma.. I already knew it, he said. I had a hunch. I had a hunch that it was cancer. … All the signs were there, because I was doing research. And everything that I researched pointed to cancer.. Alexus immediately started chemotherapy. The cancer was in her lymph nodes, her liver and her bone marrow. In total, she had 12 bone ...
Buy Zitrocin Online! Zitrocin is an antibiotic used to treat a variety of bacterial infections, such as cat-scratch disease, ear infections, infections of the skin or surrounding tissue, and throat or tonsil infections. Doctors may also prescribe Zitrocin for genital infections and sexually transmitted diseases, such as gonorrhea, infections of the urethra or cervix, genital ulcers, and severe pelvic inflammatory disease.
Catscratch disease, Catscratch fever, Benign inoculation lymphoreticulosis, Cat scratch disease, CSD, Benign lymphoreticulosis, Subacute regional lymphadenitis. Authoritative facts from DermNet New Zealand.
Even seemingly healthy pets can carry parasites, bacteria, or viruses that cause mild to life-threatening illness in their owners.. Of the 250 diseases that can be passed between animals and people, more than 100 can come from household pets, says researcher Bruno Chomel, D.V.M., Ph.D., at the University of California School of Veterinary Medicine.. Dr. Chomels research was published in the February issue of the journal Emerging Infectious Diseases. He cited a 69-year-old man whose dog slept under the covers with him and licked his hip replacement wound. The man came down with meningitis. In another incident, a 9-year-old boy picked up plague, a potentially deadly bacterial infection, from sleeping with his flea-infested cat.. But zoonotic diseases can also be passed to people who kiss their pets or are licked by them. In addition to meningitis and plague, other animal-people infections include hookworm, roundworm, and cat scratch disease.. ...
Myzocytosis "Bartonella henselae" (PDF). Dramsi, Shaynoor; Cossart, Pascale (2002-03-18). "Listeriolysin O". The Journal of ... Bacterial examples include: Bartonella henselae Francisella tularensis Listeria monocytogenes Salmonella Typhi Brucella ...
Axel Schmidt (1998). Bartonella and Afipia species emphasizing Bartonella henselae. Basel, New York: Karger. ISBN 3-8055-6649-2 ...
Often caused by Bartonella henselae (cat scratch disease). v t e. ...
Lyme disease or Bartonella henselae may also cause encephalitis.[citation needed] Other bacterial pathogens, like Mycoplasma ...
... henselae (originally known as Rochalimea henselae before the genera Bartonella and Rochalimea were combined) and B. ... Bartonella henselae is a fastidious, intracellular, Gram-negative bacterium. The cat was recognized as the natural reservoir of ... Cat-scratch disease is caused by the bacterium Bartonella henselae which is believed to be spread by the cat's saliva. Young ... Higgins JA, Radulovic S, Jaworski DC, Azad AF (1996). "Acquisition of the cat scratch disease agent Bartonella henselae by cat ...
Widening Spectrum of Bartonella henselae Infection". Pediatrics. 121 (5): e1413-e1425. doi:10.1542/peds.2007-1897. ISSN 0031- ...
Bartonella henselae: BH11960. KEGG Database. [2]. Aslmark, C.M., et al. 2004. The louse-borne human pathogen Bartonella ... Bartonella henselae hypothetical protein 11960 (BH11960) is encoded by the BH11960 gene. This hypothetical protein is conserved ... "Hypothetical protein BH11960 (Bartonella henselaei str. Houston-1". [1]. The function of the BH11960 protein is not known, but ... The promoter is ubiquitously conserved in the other Bartonella species and contains a TATA box. BH11960 is the largest of the ...
It is caused by either Bartonella henselae or B. quintana. B. henselae is most often transmitted through a cat scratch or bite ... If a cat is carrying Bartonella henselae, then it may not exhibit any symptoms. Cats may be bacteremic for weeks to years, but ... Bacillary angiomatosis (BA) is a form of angiomatosis associated with bacteria of the genus Bartonella. Cutaneous BA is ... December 1997). "Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis". N. Engl. J ...
... s can transmit Rickettsia typhi, Rickettsia felis, Bartonella henselae, and the myxomatosis virus. They can carry ...
The BadA protein is another example of a TAA found in Bartonella henselae bacteria. Bartonella henselae is the causative agent ... Neisseria meningitidis UspA1 and A2 of Moraxella catarrhalis Hia and Hsf of Haemophilus influenzae BadA of Bartonella henselae ... 2008). Ghosh P (ed.). "Structure of the head of the Bartonella adhesin BadA". PLOS Pathog. 4 (8): e1000119. doi:10.1371/journal ... Harms A, Dehio C (2012). "Intruders below the radar: molecular pathogenesis of Bartonella spp". Clin Microbiol Rev. 25 (1): 42- ...
... of Bartonella henselae". Infect. Immun. 73 (7): 4205-13. doi:10.1128/IAI.73.7.4205-4213.2005. PMC 1168562. PMID 15972511. " ... A similar factor has been identified in Bartonella henselae. The CAMP test can be used to identify Streptococcus agalactiae. ...
Bartonella henselae) Metabolic disease (e.g., hyperosmolar hyperglycemic state) The most common cause of expressive aphasia is ... "Expressive Aphasia as a Presentation of Encephalitis with Bartonella henselae Infection in an Immunocompetent Adult". The Yale ...
It is also important for confirmation of Bartonella henselae, a causative organism in cat-scratch disease. Warthin-Starry ...
Bartonella quintana is closely related to Bartonella henselae, the agent of cat scratch fever and bacillary angiomatosis. The ... Bartonella quintana is transmitted by contamination of a skin abrasion or louse-bite wound with the faeces of an infected body ... Ohl, M. E.; Spach, D. H. (1 July 2000). "Bartonella quintana and Urban Trench Fever". Clinical Infectious Diseases. 31 (1): 131 ... Comer, James A. (25 November 1996). "Antibodies to Bartonella Species in Inner-city Intravenous Drug Users in Baltimore, Md". ...
Cat-scratch disease is caused by Bartonella henselae and Bartonella quintana from fleas which are endemic in cats. Toxocariasis ...
2004). "The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae". ...
Bacterial causes associated with TM include Mycoplasma pneumoniae, Bartonella henselae, and the types of Borrelia that cause ...
USA carrying Bartonella clarridgeiae, Bartonella henselae and Rickettsia sp. RF2125". Veterinary Parasitology, Regional Studies ...
Spinella found that one patient with bartonella henselae also had anti-cardiolipin antibodies, suggesting that bartonella may ... Beyond cat scratch disease: a case report of bartonella infection mimicking vasculitic disorder. Case Rep Infect Dis. 2012;2012 ...
Acute hepatitis is caused by Neisseria meningitidis, Neisseria gonorrhoeae, Bartonella henselae, Borrelia burgdorferi, ...
It is used to find the organisms that cause cat-scratch disease (Bartonella henselae) and syphilis (Treponema pallidum) and ...
Cat-scratch disease is an infection caused by the bacterial organism Bartonella henselae, typically acquired by a scratch from ...
"Bartonella henselae" (PDF).. .mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes ...
The study found the most prevalent infection to be Bartonella henselae, the cause of cat-scratch disease in humans, with 33.6% ...
Bartonella henselae. The eight edition (1955) erroneously listed actinomycosis as a fungal disease. In the ninth edition, ...
... in Bartonella species (i.e. B. henselae, B. clarridgeiae, B. tribocorum, B. quintana, B. bacilliformis, B. grahamii), in ... Bartonella species (i.e. B. henselae, B. clarridgeiae, B. tribocorum, B. quintana, B. bacilliformis, B. grahamii). All these ... In Bartonella species the αr45 upstream gene was always found to code for a protein containing a rhodanase domain. In the ... This analysis also revealed an extended conserved sequence stretch among the promoters of the Brucella and Bartonella αr45 sRNA ...
cause septic spinal arthritis Eikenella corrodens - human bites Pasteurella multocida, bartonella henselae, capnocytophaga - ...
The bite from a cat can infect a person with: Cat-scratch disease, caused by the bacterium Bartonella henselae Cat-scratch ... The resident flora in the mouth of the domestic cat includes Pasteurella, Staph, Bartonella, and Streptococcus species. Bites ...
Bartonella henselae Francisella tularensis herpes simplex virus type 1 Paracoccidioides brasiliensis eMedicine.com, retrieved 2 ...
Newly recognized (since the 1980s): Acanthamebiasis Australian bat lyssavirus Babesia, atypical Bartonella henselae ...
Cat-scratch disease is caused by Bartonella henselae and Bartonella quintana from fleas which are endemic in cats. Toxocariasis ... Bartonella henselae cats bites or scratches from infected cats Chagas disease Trypanosoma cruzi armadillos, Triatominae ( ...
Either B. henselae or B. quintana *Bacillary angiomatosis. *Bartonella bacilliformis *Carrion's disease, Verruga peruana ...
Bartonella henselae, and the myxomatosis virus.[30]:73 They can carry Hymenolepiasis tapeworms[32] and Trypanosome protozoans.[ ...
Either B. henselae or B. quintana *Bacillary angiomatosis. *Bartonella bacilliformis *Carrion's disease, Verruga peruana ...
Bartonellosis: Bartonella henselae (പൂച്ചമാന്തി രോഗം) · Bartonella quintana (Trench fever) · either henselae or quintana ( ...
either henselae or quintana *Bacillary angiomatosis. *Bartonella bacilliformis *Carrion's disease, Verruga peruana ...
nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and To Remove the ... People's Pharmacy Radio Podcast: Bartonella, website. *May 18. 2012 Bartonella spp. bacteremia and rheumatic symptoms in ... Bartonella species have been infecting humans for thousands of years, as demonstrated by Bartonella quintana DNA in a 4000-year ... Treatment is dependent on which species or strain of Bartonella is found in a given patient. While Bartonella species are ...
Bartonella henselae Cellulitis usually Group A Streptococcus and Staphylococcus Chagas Disease (American trypanosomiasis) ...
Bartonellosis: Bartonella henselae (Cat scratch disease) · Bartonella quintana (Trench fever) · either henselae or quintana ( ...
Either B. henselae or B. quintana *Bacillary angiomatosis. *Bartonella bacilliformis *Carrion's disease, Verruga peruana ...
Bartonella henselae bacilli in cardiac valve of a patient with blood culture-negative endocarditis. The bacilli appear as black ...
Bartonella henselae. Cellulitis. usually Group A Streptococcus and Staphylococcus. Chagas Disease (American trypanosomiasis). ...
Cat-scratch disease is an infection caused by the bacterial organism Bartonella henselae, typically acquired by a scratch from ...
nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and To Remove the ... Berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease" (PDF). Parasites & Vectors. 3 ... Bartonella vinsonii is a gram-negative bacteria from the genus of Bartonella which was isolated from dogs Rochalimaea vinsonii ... Straininfo of Bartonella vinsonii "Taxonomy - Bartonella vinsonii (Rochalimaea vinsonii)". The Universal Protein Resource ( ...
Bartonella henselae, Bartonella koehlerae and 'Candidatus Mycoplasma haemominutum' in a cat diagnosed with splenic ... Bartonella doshiae Bartonella grahamii Droz S, Chi B, Horn E, Steigerwalt AG, Whitney AM, Brenner DJ (1999). "Bartonella ... Bartonella-Associated Infections - CDC Information on Bartonella - lymedisease.org Bartonella species - List of Prokaryotic ... Mascarelli, Patricia E. "Bartonella henselae and B. koehlerae DNA in Birds." Qurollo, B. A.; Balakrishnan, N.; Cannon, C. Z.; ...
... Sue Anne Brenner sbrenne at emory.edu Thu Apr 11 10:36:39 EST 1996 *Previous message: bartonella henselae ... B. henselae grows reasonably well on rabbit blood agar plates. If plating blood, it may be easier to count colonies if the ... B. henselae can also grow in some cell lines, including vero cells and human epithelial cells. If yourre attempting to isolate ... B. henselae from blood, lysis tubes such as the Isolator may be superior to other methods. For other body substances, there are ...
Rochalimaea henselae. Other names i. ›ATCC 49882. ›ATCC:49882D-5. ›Bartonella henselae (Regnery et al. 1992) Brenner et al. ...
hypothetical protein Q655_00693 [Bartonella henselae JK 51] hypothetical protein Q655_00693 [Bartonella henselae JK 51]. gi, ...
Cats do have the capacity to spread Bartonella henselae to humans. Kittens pose a greater risk than cats and pass the bacterium ... At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. Cats who are ... There have been reports of Bartonella henselae found inside fleas, however, there have been no instances of flea bites causing ... Cat Scratch Disease (Bartonella henselae Infection) Commonly abbreviated as CSD, Cat Scratch Disease is an infectious disease ...
Cat scratch disease (CSD) is a common zoonosis in children caused by Bartonella henselae (B. henselae). Typical CSD, which ... Bartonella henselae Infection: An Uncommon Mimicker of Autoimmune Disease. Despoina N. Maritsi,1,2 Diagoras Zarganis,2 Zoi ... R. F. Jacobs and G. E. Schutze, "Bartonella henselae as a cause of prolonged fever and fever of unknown origin in children," ... A. Sander, M. Posselt, N. Böhm, M. Ruess, and M. Altwegg, "Detection of Bartonella henselae DNA by two different PCR assays and ...
... Dionna M. Mathews,1 Katie M. Vance,2 Pamela M. ... Y. Kodama, N. Maeno, J. Nishi et al., "Multifocal osteomyelitis due to Bartonella henselae in a child without focal pain," ... I. Pons, I. Sanfeliu, N. Cardenosa, M. M. Nogueras, B. Font, and F. Segura, "Serological evidence of Bartonella henselae ... K. Mazur-Melewska, K. Jonczyk-Potoczna, A. Mania et al., "The significance of Bartonella henselae bacteria for oncological ...
... henselae as an infectious agent in dogs. Due to the paucity of information regarding the B. henselae serology in dogs, we ... In contrast to the large body of literature regarding Bartonella henselae in humans and cats, there is little information about ... Bartonella henselae IgG antibodies are prevalent in dogs from southeastern USA Vet Res. Sep-Oct 2004;35(5):585-95. doi: 10.1051 ... In contrast to the large body of literature regarding Bartonella henselae in humans and cats, there is little information about ...
... ,ARUP Laboratories is a national reference laboratory and a ... Bartonella Culture. 2. Bartonella DNA, Tissue, PCR. 3. Bartonella DNA, PCR. 4. Bartonella henselae Antibody, IgG by IFA. 5. ... Bartonella quintana Antibody, IgM by IFA. 8. Bartonella quintana Antibody, IgG by IFA. 9. Culture, Bartonella. 10. Adenovirus ... Bartonella quintana Antibodies, IgG & IgM by IFA. 6. Bartonellahenselae Antibody, IgM by IFA. 7. ...
Bartonella henselae is a member of the class of the Bartonella genus, one of the most common type of bacteria in the world. ... Bartonella henselae is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis ... Peliosis hepatis caused by B. henselae can occur alone or develop with cutaneous bacillary angiomatosis or bacteremia. Patients ... Retrieved from "https://www.wikidoc.org/index.php?title=Bartonella_henselae&oldid=1353922" ...
... we demonstrated that HemS from Bartonella henselae expressed in E. coli allows the release of iron from heme. Purified HemS ... For Bartonella, the gene cluster devoted to the synthesis of the complete heme uptake system also contains a gene encoding for ... Therefore, Bartonella genome encodes for a complete heme uptake system allowing the transportation of this compound across the ... Heme has been proposed to be used as an iron source for Bartonella since these bacteria do not synthesize a complete system ...
Bartonella henselae [bär′′ tə-nel′ə henz′ ə-lā] On This Page ... It was later called Bartonella bacilliformis.. The species B. henselae was named after Diane Hensel, a technologist in the ... Bartonella henselae . Emerging Infectious Diseases. 2008;14(6):980. doi:10.3201/eid1406.080980.. ... The organism was first named Rochalimaea henselae and then B. henselae, when sequencing showed identity with that genus. ...
Bartonella henselae. Mutation(s): 0 Gene Names: invB, BH01650. Find proteins for A0A0H3LVG3 (Bartonella henselae (strain ATCC ... Crystal Structure of Invasion Associated Protein B from Bartonella Henselae.. Patskovsky, Y., Ozyurt, S., Freeman, J., Slocombe ... Crystal structure of invasion associated protein b from bartonella henselae. *DOI: 10.2210/pdb3DTD/pdb ...
Molecular evidence of perinatal transmission of Bartonella vinsonii subsp. berkhoffii and Bartonella henselae to a child. J ... Severe anemia and cholestatic hepatitis are associated with bartonella infections. A putative vertical Bartonella henselae ... Abortion related to infection by Bartonella henselae has already been described in equines3. Bilavsky et al. (2012) related a ... Detection of Bartonella henselae DNA in clinical samples including peripheral blood of immune competent and immune compromised ...
A library of Bartonella henselae DNA was screened with antibody raised to the bacteriophage particle associated with this ... Analysis of 36-kilodalton protein (PapA) associated with the bacteriophage particle of Bartonella henselae.. Anderson B1, ... Taken together, these results suggest that papA is present on a mobile genetic element of the B. henselae genome and is also ... A papA-specific probe hybridized to multiple bands of B. henselae genomic DNA digested with several different restriction ...
... henselae) may induce clinical disorders in cats in natural conditions from a comparison of the serological status for B. ... henselae with the serostatus for feline immunodeficiency virus (FIV) and several clinical characteristics in 170 domestic cats ... It was found that Bartonella henselae (B. henselae) may induce clinical disorders in cats in natural conditions from a ... Does coinfection of Bartonella henselae and FIV induce clinical disorders in cats? Microbiol Immunol. 1996;40(9):617-20. doi: ...
We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red ... Bartonella henselae transmission by blood transfusion in mice. Caution, may cause upset!!!!. Support Forums. , ... We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red ... Bartonella can also be passed on via tick bites...along with lyme and other coinfections.. Has your son had a tick bite...and/ ...
... henselae SA2; 3, B. henselae Houston-1; 4, B. henselae URBHLLY8; 5, B. henselae URBHLIE9; 6, B. henselae Cat6; 7, B. henselae ... Coinfection with Bartonella clarridgeiae and Bartonella henselae and with different Bartonella henselae strains in domestic ... Prevalence of Bartonella henselae and Bartonella clarridgeiae in stray cats. J. Clin. Microbiol.35:1327-1331. ... Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). J. Clin. ...
Abcam provides specific protocols for Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) : ...
VIEIRA-DAMIANI, Gislaine et al. Bartonella henselae infection induces a persistent mechanical hypersensitivity in mice. Rev. ... Bartonella spp. are re-emerging and neglected bacterial pathogens. The natural reservoirs for several species of this genus are ... Our group has already demonstrated that B. henselae -infected sickle cell disease mice present with hyperalgesia. We ... The present study has demonstrated that B. henselae infection induces persistent mechanical hypersensitivity, a signal ...
Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) has been cited in 4 publications. Find out more about the ... Johnson R et al. Identification of Bartonella henselae in an aborted equine fetus. Vet Pathol 46:277-81 (2009). PubMed: ... Vermi W et al. Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma. Blood 107:454 ... Maggi RG et al. Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure. Parasit Vectors 6 ...
Splenorenal Manifestations of Bartonella henselae Infection in a Pediatric Patient.(Case Report, Report, Case study) by Case ... It was only as recently as 1992 that the pathogen Bartonella henselae was isolated [5]. Bartonella henselae is an intracellular ... the Bartonella henselae IgG was positive at ,1:1024, consistent with presence of IgG antibody to Bartonella henselae, ... these endothelial cells promote proliferation of Bartonella henselae [11]. The clinical presentation of Bartonella henselae ...
Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... Bartonella henselae participates in host recognition by the type IV secretion system as a homolog of the virB5 family. ... Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... It has been found that up to 95% of patients with Cat Scratch Disease show antibodies against Bartonella henselae antigens. ...
Bartonella 26kDa is expressed with a -10x His tag at N-terminus. Bartonella henselae of outer membrane protein p26 has an ... Recombinant Bartonella Henselae 26kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... important nucleotide identity with orthologs in Bartonella spp, Brucella spp in addition to more than a few plant-associated ... Bartonella henselae of outer membrane protein p26 has an important nucleotide identity with orthologs in Bartonella spp, ...
The 16S-23S intergenic transcribed spacer region obtained from each porpoise was 99.8% similar to that of B. henselae strain ... Currently, the geographic distribution, mode of transmission, reservoir potential, and pathogenicity of bloodborne Bartonella ... we directly amplified Bartonella species DNA from blood of a harbor porpoise stranded along the northern North Carolina coast ... We report detection of Bartonella henselae DNA in blood samples from 2 harbor porpoises (Phocoena phocoena). By using real-time ...
Bartonella henselae). Cat scratch disease (CSD), also called cat scratch fever, is a bacterial infection caused by Bartonella ... Reporting Cat Scratch Disease (Infection Caused by Bartonella spp.) Healthcare providers and clinical laboratories are required ... henselae, which is generally spread to people through cat bites or scratches. Most healthy people do not develop any symptoms, ...
健常人の血清抗Bartonella henselae IgG抗体保有率 [in Japanese] Prevalence of Serum IgG Antibody against Bartonella henselae in an ... Determination of Anti-Bartonella henselae Antibody by Indirect Fluorescence Antibody Test : Comparison of Two Types of Antigen ... Survey of Veterinary Professionals for Antibodies to Bartonella henselae in Japan KUMASAKA Kazunari , ARASHIMA Yasutomo , YANAI ... Seroprevalence of Bartonella henselae in Patients with Uveitis and Healthy Individuals in Tokyo ...
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae). ,p>This subsection of the ,a href="http ... sp,Q6G4T2,FPG_BARHE Formamidopyrimidine-DNA glycosylase OS=Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) OX= ... cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › BartonellaBartonella ...
NAME: Bartonella henselae. SYNONYM OR CROSS REFERENCE: Formerly Rochalimaea henselae. Cat-scratch diseaseFootnote 1-Footnote 3 ... Molecular characterization of resistance to fluoroquinolones in Bartonella henselae and Bartonella quintana. Journal of ... Pathogen Safety Data Sheets: Infectious Substances - Bartonella henselae. PATHOGEN SAFETY DATA SHEET - INFECTIOUS SUBSTANCES. ... Biswas, S., Raoult, D., & Rolain, J. M. (2006). Molecular characterization of resistance to macrolides in Bartonella henselae. ...
... Andersson, SGE Uppsala ... the arthropod-borne human pathogens Rickettsia prowazekii and Bartonella henselae provide examples of bacteria with obligate ... genome sequence; infection; pathogenesis; intracellular life style; alpha subdivision of proteobacteria; Rickettsia; Bartonella ...
In order to identify immunoreactive Bartonella henselae proteins, B. henselae antiserum from an experimentally infected cat was ... Cloning, Characterization, and Expression of Bartonella henselae p26. Jonathan A. Werner, Sunlian Feng, Rickie W. Kasten, Emir ... Cloning, Characterization, and Expression of Bartonella henselae p26. Jonathan A. Werner, Sunlian Feng, Rickie W. Kasten, Emir ... Cloning, Characterization, and Expression of Bartonella henselae p26. Jonathan A. Werner, Sunlian Feng, Rickie W. Kasten, Emir ...
  • B. henselae infection can appear up to 10 days after exposure to the microbe. (wikipedia.org)
  • these children got endocarditis from B. henselae infection. (wikipedia.org)
  • In rare cases, osteomyelitis, an infection in the bone, can be a manifestation of B. henselae. (wikipedia.org)
  • Subsequently, raised titers (IgM 1 : 32, IgG 1 : 256) against Bartonella confirmed the diagnosis of B. henselae infection. (hindawi.com)
  • Nowadays, with the use of modern diagnostic tools the clinical spectrum of B. henselae disease has further expanded to include various additional clinical entities such as disseminated infection and septicemia, neurological, cardiovascular, ocular, and musculoskeletal manifestations [ 2 ]. (hindawi.com)
  • Multifocal osteomyelitis due to Bartonella henselae in a child without focal pain," Journal of Infection and Chemotherapy , vol. 13, no. 5, pp. 350-352, 2007. (hindawi.com)
  • Nevertheless, further studies are needed to evaluate the epidemiological, clinical and zoonotic relevance of B. henselae infection in dogs. (nih.gov)
  • A putative vertical Bartonella henselae infection was defined on the basis of ultrastructural and molecular analyses in a three-year-old child with anemia, jaundice and hepatosplenomegaly since birth. (scielo.br)
  • Abortion related to infection by Bartonella henselae has already been described in equines 3 . (scielo.br)
  • We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. (healingwell.com)
  • Transmission of B. henselae by transfusion is possible in mice even when donor animals have undetectable bloodstream infection. (healingwell.com)
  • The present study has demonstrated that B. henselae infection induces persistent mechanical hypersensitivity, a signal consistent with pain. (scielo.br)
  • Splenorenal Manifestations of Bartonella henselae Infection in a Pediatric Patient. (thefreelibrary.com)
  • More recently, renal microabscesses as a result of Bartonella henselae infection have also been reported [4]. (thefreelibrary.com)
  • 1:1024, consistent with presence of IgG antibody to Bartonella henselae, suggestive of current or prior infection. (thefreelibrary.com)
  • frequently induce persistent intravascular infections, particularly in reservoir hosts, attributing disease causation to Bartonella infection in animals or in human patients has been difficult, and satisfying Koch postulates for disease causation remains challenging ( 21 ). (cdc.gov)
  • The relative sensitivity of diagnostic methods used to detect Bartonella species infection greatly influences the ability to establish disease causation. (cdc.gov)
  • Cat scratch disease (CSD), also called cat scratch fever, is a bacterial infection caused by Bartonella henselae, which is generally spread to people through cat bites or scratches. (mn.us)
  • Reporting Cat Scratch Disease (Infection Caused by Bartonella spp. (mn.us)
  • Comparative nucleotide sequence analysis showed that p26 is a potential marker for molecular diagnosis of infection, as well as for identification to species level and genotyping of Bartonella sp. (asm.org)
  • Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from The Philippines. (ajtmh.org)
  • One hundred seven domestic cats from The Philippines were serologically tested to establish the prevalence of Bartonella infection. (ajtmh.org)
  • Domestic cats represent a large reservoir of Bartonella infection in the Philippines. (ajtmh.org)
  • Although the infection usually resolves spontaneously without treatment in healthy adults, bartonellosis may lead to severe complications in young children and immunocompromised patients, and there is new evidence suggesting that B. henselae may be associated with a broader range of clinical symptoms then previously believed. (iucr.org)
  • More than 40 Bartonella species have been reported to infect mammalian reservoir hosts, and infection often leads to chronic bacteremia. (akcchf.org)
  • This proposed study will result in development of a novel and sensitive ELISA assay for diagnosing Bartonella infection in dogs and will provide insights into the development of effective vaccine candidates for preventing Bartonella infection. (akcchf.org)
  • HIV-positivity appears to be a significant risk factor for Bartonella infection, compared with healthy subjects. (scielo.org.za)
  • Infection with one or more Bartonella sp. (biomedcentral.com)
  • The array was probed with a collection of 62 uninfected, 62 infected, and 8 "specific-pathogen free" naïve cat sera, to profile the antibody repertoire elicited during natural Bartonella henselae infection. (escholarship.org)
  • Our protein microarray platform provides a high-throughput, comprehensive analysis of the feline humoral immune response to natural infection with the alpha-proteobacterium B. henselae at an antigen-specific, sera-specific, and genome-wide level. (escholarship.org)
  • However, only several cases of B. henselae infection have been reported in Korea. (kjim.org)
  • Surveys on the risk factors for B. henselae infection were conducted simultaneously. (kjim.org)
  • In Korea, the seroprevalence of B. henselae is higher than expected, suggesting that Bartonella infection due to B. henselae is not uncommon. (kjim.org)
  • In Korea, only a few cases of Bartonella infection have been reported [ 2 ]. (kjim.org)
  • These prior studies suggest that a higher incidence of B. henselae infection should be expected. (kjim.org)
  • We retrospectively evaluated the presence of immunoglobulin G and M class antibodies to B. henselae in 508 children living in central Italy who were apparently free of any features suggesting B. henselae infection. (oup.com)
  • We found that B. henselae infection is common among children in central Italy, occurs early in life, is in most cases asymptomatic, and resolves spontaneously. (oup.com)
  • One of the most important species of the Bartonella genus is B. henselae that causes a zoonotic infection, cat scratch disease (CSD). (iranjournals.ir)
  • 1,2 The most important species of this genus is B. henselae that causes a zoonotic infection, cat scratch disease (CSD). (iranjournals.ir)
  • About 40% of cats carry B. henselae at some time in their lives, although most cats with this infection show NO signs of illness. (cdc.gov)
  • Kittens younger than 1 year are more likely to have B. henselae infection and to spread the germ to people. (cdc.gov)
  • Most cats with B. henselae infection show NO signs of illness, but on rare occasions this disease can cause inflammation of the heart-making cats very sick with labored breathing. (cdc.gov)
  • B. henselae infection may also develop in the mouth, urinary system, or eyes. (cdc.gov)
  • Bartonella henselae is able to internalize endothelial progenitor cells (EPCs), which are resistant to the infection of other common pathogens. (unicampania.it)
  • We observed a marked activation of the inflammatory response by Real-time PCR and ELISA in coinfected cells compared to B. henselae-infected cells (63 vs 23 up-regulated genes), and after EPCs infection with mutant B. fragilis ΔPSA (≅90% up-regulated genes) compared to B. fragilis. (unicampania.it)
  • Wong MTDolan MJLattuada CP et al Neuroretinitis, aseptic meningitis, and lymphadenitis associated with Bartonella (Rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1. (jamanetwork.com)
  • Breitschwerd EBKordick DL Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. (jamanetwork.com)
  • Bartonella henselae is a fastidious gram-negative bacterium usually causing self limiting infections in immunocompetent individuals but often causes potentially life threatening infection , such as bacillary angiomatosis in immunocompromised patients . (bvsalud.org)
  • We undertook this study to standardize methods to characterize B. henselae in clinical samples to diagnose Bartonella infection correctly. (bvsalud.org)
  • Infection of humans with the zoonotic bacterium Bartonella henselae (Bh) can result in a range of clinical symptoms and disease including lymphadenopathy associated with localized Bh infection observed in cat-scratch disease, to endocarditis and bacteremia resulting from systemic disease. (grantome.com)
  • This unusual angiogenic host response to infection is unique among bacteria to certain Bartonella species. (grantome.com)
  • We expect to identify genes from Bartonella henselae that are required for infection in order to better understand how this bacterium causes disease with the long-term goals of developing new strategies to control, prevent and treat disease in patients infected with this bacterium. (grantome.com)
  • In immunocompromised patients, infection with B. henselae is characterized by more severe clinical forms than in non-immunocompromised individuals. (elsevier.com)
  • Such a difference could be associated with a reduced immune response to the infection, especially a reduced ability to phagocytize Bartonella organisms in the splenectomized cats. (elsevier.com)
  • A diagnosis of B. henselae infection was made according to her personal history that divulged frequent contacts with cats and to a high titre of immunoglobulin G (IgG) and IgM antibodies for this agent. (wiley.com)
  • To confirm B. henselae infection, polymerase chain reaction (PCR) analysis using aspirates of cervical lymph node was performed and the presence of B. henselae DNA was demonstrated. (pertussis.us)
  • Rare complications of B. henselae infection are bacillary angiomatosis and Parinaud's oculolandular syndrome. (lymphedemapeople.com)
  • The endothelium is a specific target for Bartonella henselae, and endothelial cell infection represents an important step in the pathogenesis of cat scratch disease and bacillary angiomatosis. (unibas.ch)
  • In light of these problems, a laboratory diagnosis of a Bartonella infection is generally made by serology ( 5 ) or molecular approaches ( 7 ). (asm.org)
  • Our observation has direct consequences when, e.g., infection experiments are performed with such liquid-grown Bartonella spp. (asm.org)
  • A library of Bartonella henselae DNA was screened with antibody raised to the bacteriophage particle associated with this organism. (nih.gov)
  • serology was performed by indirect fluorescent antibody testing and confocal laser scanning microscopy was used to visualize B. henselae organisms in resected brain. (biomedcentral.com)
  • The cloned gene was expressed in Escherichia coli , and the purified Pap31 protein elicited strong antibody responses in mice and was reactive with rabbit anti-live B. henselae and mouse anti-Pap31 antibodies by Western blotting. (asm.org)
  • Although IFAs have a high sensitivity for Bartonella antibody detection, they have various limitations including cross-reactivity with other closely-related human pathogens. (scielo.org.za)
  • berkhoffii genotypes I-III, B. henselae and B. koehlerae indirect fluorescent antibody assays and for bacteremia using the BAPGM enrichment blood culture platform. (biomedcentral.com)
  • Igg Antibody Laboratories manufactures the bartonella henselae antibody igg 0050091 reagents distributed by Genprice. (kimgevaert.be)
  • The Bartonella Henselae Antibody Igg 0050091 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (kimgevaert.be)
  • All B. henselae strains were found positive with this antibody. (abcam.cn)
  • Here we describe the diagnosis of a 12-year-old child with lymphadenopathy in Croatia with cat-scratch disease based on antibody detection and clinical signs, and the subsequent culturing and genotyping of B.henselae from the cat's blood. (biomedcentral.com)
  • Immunofluorescent antibody test performed during the convalescent stage was positive for B. henselae. (pertussis.us)
  • B. henselae is a member of the genus Bartonella, one of the most common types of bacteria in the world. (wikipedia.org)
  • Commonly abbreviated as CSD, Cat Scratch Disease is an infectious disease caused by the bacteria Bartonella henselae. (medic8.com)
  • The significance of Bartonella henselae bacteria for oncological diagnosis in children," Infectious Agents and Cancer , vol. 10, no. 1, p. 30, 2015. (hindawi.com)
  • Bartonella is a genus of gram-negative bacteria named after Peruvian scientist Alberto Leonardo Barton. (cdc.gov)
  • Bartonella henselae of outer membrane protein p26 has an important nucleotide identity with orthologs in Bartonella spp, Brucella spp in addition to more than a few plant-associated bacteria. (prospecbio.com)
  • Within the alpha subdivision of proteobacteria, the arthropod-borne human pathogens Rickettsia prowazekii and Bartonella henselae provide examples of bacteria with obligate and facultative intracellular life styles, respectively. (diva-portal.org)
  • Bartonella, a genus of gram-negative bacteria, are associated with a wide spectrum of life-threatening diseases in animals and humans. (akcchf.org)
  • As intravascular, intra-erythrocytic and endotheliotropic bacteria, it is possible that B. henselae initially induced a vasculitis, resulting in secondary cerebral infarction, tissue necrosis and surgical resection. (biomedcentral.com)
  • Over the past decade, evolving evidence supports the fact that these bacteria can induce long-lasting intravascular infections in animals that serve as reservoir-adapted hosts, whereas, more recently a number of Bartonella sp. (biomedcentral.com)
  • Bartonella genus contains at least 20 species and subspecies of small, gram-negative, polymorphic, fastidious and hemotropic bacteria that infect humans and a variety of mammals. (iranjournals.ir)
  • Bartonella henselae is a very small rod-shaped bacteria and it is much easier to identify these under the microscope by using a red chromogen such as AEC. (abcam.cn)
  • Additional studies indicated that B. henselae-induced effects did not require living bacteria or Bartonella lipopolysaccharides. (unibas.ch)
  • Human- and animal-pathogenic Bartonella species are fastidious and slow-growing bacteria difficult to isolate and cultivate. (asm.org)
  • Bartonella vinsonii is a gram-negative bacteria from the genus of Bartonella which was isolated from dogs Rochalimaea vinsonii was reclassified to Bartonella vinsonii. (wikipedia.org)
  • 1996) observed that anemia and elevated serum alkaline phosphatase were associated with B. henselae and Bartonella quintana infections 8 . (scielo.br)
  • Pap31 is homologous to the multigene heparin-binding protein (encoded by hbp ) family in Bartonella quintana , Neisseria opacity proteins (Opa), Brucella OMP31 (a putative porin), and Agrobacterium tumefaciens OMP25 (an immunogenic surface protein) ( 34 ). (asm.org)
  • B. henselae , B. quintana , and B. vinsonii ) cause a persistent intraerythrocytic bacteremia in their respective mammalian reservoir hosts ( 7 ). (asm.org)
  • The aims were to determine the IgG and IgM seroprevalences of Bartonella henselae and Bartonella quintana in immunocompromised and immunocompetent individuals using an immunofluorescence assay (IFA). (scielo.org.za)
  • Among them, Bartonella henselae, Bartonella bacilliformis, and Bartonella quintana are important pathogens that cause infections in humans [ 1 ]. (kjim.org)
  • We describe a serosurvey for Rickettsia rickettsii , R. typhi , Coxiella burnetii , Bartonella henselae , B. quintana , and Ehrlichia chaffeensis in 437 healthy people from a Brazilian rural community. (fiocruz.br)
  • Low seropositivity rates for R. rickettsii , R. typhi , and C. burnetii contrasted with higher rates of seropositivity for B. quintana , B. henselae , and E. chaffeensis . (fiocruz.br)
  • Given these above mentioned facts and the much-appropriated local ecologic conditions for rickettsial infections we choose this particular region for studying the seroprevalence rates for R. typhi , C. burnetii , B. henselae , B. quintana , and E. chaffeensis as well as R. rickettsii infections among healthy individuals from a Brazilian rural community. (fiocruz.br)
  • Serum samples from 437 healthy individuals of both sexes aged from 5 to 92 years old, living in the county of Piau, state of Minas Gerais, Brazil were tested for the presence of R. rickettsii , R. typhi , C. burnetii phase I and phase II, B. henselae , B. quintana , and E. chaffeensis IgG and IgM antibodies. (fiocruz.br)
  • are important pathogens in human and veterinary medicine, of which B. henselae and B. quintana are considered to represent the most-relevant human-pathogenic Bartonella species ( 8 ). (asm.org)
  • Cerebrospinal fluid polymerase chain reaction did not detect B henselae or B quintana . (aappublications.org)
  • Proposals To Unify the Genera Bartonella and Rochalimaea, with Descriptions of Bartonella quintana comb. (wikipedia.org)
  • The organism was first named Rochalimaea henselae and then B. henselae, when sequencing showed identity with that genus. (cdc.gov)
  • By 16S rRNA gene sequencing, the bacterium was identified as Rochalimaea ( Bartonella ) spp. (asm.org)
  • Characterization of a novel Rochalimaea species, R. henselae sp. (semanticscholar.org)
  • The genus Bartonella is comprised of a rapidly increasing number of pathogenic species that induce a seemingly diverse spectrum of neurological symptoms. (biomedcentral.com)
  • Bartonella is a genus of opportunistic, Gram-negative bacilli transmitted from animals to human hosts. (scielo.org.za)
  • Due to complex nutritional requirements and slow dividing times, which necessitate a prolonged incubation period for successful isolation, members of the genus Bartonella are highly fastidious microorganisms that are difficult to document microbiologically in patient blood or tissue specimens [ 1 ]. (biomedcentral.com)
  • The bacterial genus Bartonella is distributed worldwide and poses a public health risk. (biomedcentral.com)
  • Until recently the rickettsiales order comprised the genus Rickettsia , Coxiella , Bartonella , Orientia , Anaplasma , and Ehrlichia (Raoult & Roux 1997) and despite of the resulting withdraw of some of them from this order especially due to 16S rRNA studies, they all can be functionally considered rickettsial agents (Raoult & Roux 1997, Walker 2004b). (fiocruz.br)
  • The species B. henselae was named after Diane Hensel, a technologist in the clinical microbiology laboratory, University Hospitals, Oklahoma City, who in 1985 observed a Campylobacter -like organism in blood cultures of HIV-infected patients. (cdc.gov)
  • like ( 33 ), and the novel species name, B. henselae , was proposed in 1992 ( 32 ). (asm.org)
  • By using real-time polymerase chain reaction, we directly amplified Bartonella species DNA from blood of a harbor porpoise stranded along the northern North Carolina coast and from a preenrichment blood culture from a second harbor porpoise. (cdc.gov)
  • Currently, the geographic distribution, mode of transmission, reservoir potential, and pathogenicity of bloodborne Bartonella species in porpoises have not been determined. (cdc.gov)
  • Bartonellosis is a newly emerging worldwide zoonotic disease ( 1 , 2 ) that can be caused by a spectrum of Bartonella species. (cdc.gov)
  • This method has greatly facilitated the molecular detection or isolation of Bartonella species from the blood of sick and healthy animals ( 24 ). (cdc.gov)
  • Of these six species, B. henselae is the primary agent responsible for cat scratch fever. (iucr.org)
  • At least ten Bartonella species have been implicated in association with serious diseases in dogs, including endocarditis, hemangiosarcoma, myocarditis, peliosis hepatis, polyarthritis and vasculitis. (akcchf.org)
  • Dogs throughout the United States and much of the world are exposed to Bartonella species. (akcchf.org)
  • From a public health perspective there is an increased risk of direct and vector-borne transmission of Bartonella species from animals to humans. (akcchf.org)
  • Several Bartonella species (e.g. (asm.org)
  • Furthermore, a total of 7.2% (50/690) of cats was infected with Bartonella species (0% in Hokkaido Prefecture 〜 20% in Okinawa Prefecture) and most B. henselae isolates were identified as type I. It was found for the first time that cats in Japan were infected with B. clarridgeiae alone or both B. henselae and B. clarridgeiae. (nii.ac.jp)
  • Publications] Maruyama, S.他3名: 'Prevalence of Bartonella species among pet cats in Japan'J.Microbiol.Methods. (nii.ac.jp)
  • Publications] Maruyama, S. and Katsube, Y.: 'Contributions of Microbiology, vol.1 Bartonella and Afipia species with special regard to Bartonella henselae. (nii.ac.jp)
  • Bartonella species have recently been proven to cause zoonosis. (kjim.org)
  • Bartonella henselae 12_well Substrate Slide Species Human_Canine_Equine Human samples 80 % of the research is conducted on human samples. (antibody-antibodies.com)
  • GENTAUR suppliers human normal cells, cell lines, RNA extracts and lots of antibodies and ELISA kits to Human proteins as well as Bartonella henselae 12_well Substrate Slide Species Human_Canine_Equine. (antibody-antibodies.com)
  • The most common zoonotic species is Bartonella henselae , for which cats are the major natural reservoir host. (bvsalud.org)
  • Schouls LMVan De Pol IRijpkema SGSchot CS Detection and identification of Ehrlichia , Borrelia burgdorferi sensu lato , and Bartonella species in Dutch Ixodes ricinus ticks. (jamanetwork.com)
  • Hofmeister EKKolbert CPAbdulkarim AS et al Co-segregation of a novel Bartonella species with Borrelia burgdorferi and Babesia microti in Peromyscus leucopus . (jamanetwork.com)
  • Audrey- Bartonella henselae, which is the usual species of Bartonella in cat infections is currently thought to be transmitted mostly through flea bites. (vetinfo.com)
  • Identification of Bartonella Species Isolated from Rodents from Yucatan, Mexico, and Isolation of Bartonella vinsonii subsp. (wikipedia.org)
  • Bartonella henselae, formerly Rochalimæa, is a proteobacterium that is the causative agent of cat-scratch disease (bartonellosis). (wikipedia.org)
  • Cat scratch disease (CSD) is a common zoonosis in children caused by Bartonella henselae ( B. henselae ). (hindawi.com)
  • What prompted the Dr. to test him for bartonella - did he have classic bart symptoms: sore feet, rib pain, swollen lymph nodes, scratch marks. (healingwell.com)
  • Bartonella henselae commonly presents as fever and localized lymphadenopathy in children or adolescents with a history of exposure to a scratch from a kitten or cat. (thefreelibrary.com)
  • Numerous forms of Bartonellosis are caused by Bartonella henselae as well as Cat Scratch Disease & Bacillary Angiomatosis. (prospecbio.com)
  • It has been found that up to 95% of patients with Cat Scratch Disease show antibodies against Bartonella henselae antigens. (prospecbio.com)
  • Highly immunoreactive proteins which are produced by the Bartonella henselae are the most important antigens used for the diagnosis of Cat Scratch Disease. (prospecbio.com)
  • Cat scratch fever (also known as cat scratch disease and bartonellosis) is an infectious disease caused by the proteobacterium Bartonella henselae following a cat scratch. (iucr.org)
  • Cat scratch disease, a rare cause of hypodense liver lesions, lymphadenopathy and a protruding duodenal lesion, caused by Bartonella henselae -- van Ierland-van Leeuwen et al. (bmj.com)
  • Serology for Bartonella henselae IgM was highly elevated a few weeks after presentation, consistent with the diagnosis of cat scratch disease. (bmj.com)
  • Bartonella henselae is a zoonotic, alpha Proteobacterium, historically associated with cat scratch disease (CSD), but more recently associated with persistent bacteremia, fever of unknown origin, arthritic and neurological disorders, and bacillary angiomatosis, and peliosis hepatis in immunocompromised patients. (biomedcentral.com)
  • Bartonella henselae is the zoonotic agent of cat scratch disease and causes potentially fatal infections in immunocompromised patients. (escholarship.org)
  • Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. (kjim.org)
  • Here, the cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the pathogenic bacterium Bartonella henselae, the causative bacterium of cat-scratch disease, are presented. (escholarship.org)
  • Anatoly was diagnosed yesterday with Cat Scratch Disease, caused by Bartonella Henselae . (blogspot.com)
  • Bartonella henselae causes several forms of Bartonellosis, including Cat Scratch Disease (CSD) and Bacillary Angiomatosis (BA). (diarect.com)
  • In conclusion, humans may develop cat-scratch disease when they are exposed to Bartonella henselae (BH) in the saliva of infected cats or BH-containing flea feces reaching the systemic circulation through scratches or mucous membranes. (mysciencework.com)
  • Cat Scratch Disease Cause Bartonella henselae is a pleomorphic. (ehealthglobalhealth.com)
  • Cat Scratch Disease Cause Bartonella henselae is a pleomorphic , often curved-shaped Gram-negative bacterium that's responsible for almost all CSD. (ehealthglobalhealth.com)
  • The causative bacterial agent of cat scratch disease has been identified as Bartonella henselae. (abcam.cn)
  • Cat-scratch disease caused by B. henselae in Croatia was first described in 1957. (biomedcentral.com)
  • But, Cat Scratch Disease which is the most common pathology occurring due to B. Henselae occurs throughout the world and there is no predisposition for selective geographic areas. (studentshare.org)
  • Bartonella henselae is the agent of cat-scratch disease (CSD), a chronic lymphadenopathy among children and adolescents. (microbiologyresearch.org)
  • Cat scratch disease is caused by Bartonella henselae and the domestic cat represents its main reservoir. (elsevier.com)
  • Cat Scratch - Neuroretinitis OD AND retinitis OS - Bartonella henselae positive 29 views 27 year old female with exposure to cats and prior fever. (retinagallery.com)
  • Cat scratch disease (CSD), due to Bartonella henselae , is a self-limited chronic lymphadenopathy. (wiley.com)
  • Bartonella henselae is a zoonotic, alpha Proteobacterium, historically associated with cat scratch disease (CSD), but more recently associated with persistent bacteremia, fever of unknown origin, arthritic and ne. (biomedcentral.com)
  • We report a case of cat scratch disease caused by Bartonella henselae in Korea. (pertussis.us)
  • This is the first reported case of cat scratch disease in Korea confirmed by PCR for B. henselae DNA. (pertussis.us)
  • Cat scratch disease (CSD) is a bacterial disease caused by Bartonella henselae. (lymphedemapeople.com)
  • In conclusion, B. henselae, the causative agent of cat scratch disease and bacillary angiomatosis, infects and activates endothelial cells. (unibas.ch)
  • Cat scratch disease (CSD) is typically a subacute, regional lymphadenitis caused by Bartonella henselae that is seen in children and young adults. (aappublications.org)
  • Cat scratch ( B henselae ) serum serology later returned elevated at 1:256 (1:64 is considered positive). (aappublications.org)
  • Bartonella henselae is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis . (wikidoc.org)
  • Peliosis hepatis caused by B. henselae can occur alone or develop with cutaneous bacillary angiomatosis or bacteremia. (wikidoc.org)
  • Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure. (abcam.com)
  • Bartonella bacteremia, potentially spanning a 12-year time frame, in conjunction with the therapeutic administration of immunosuppressive drugs may have resulted in a progression and potentiation of the neurological disease that was partially reversible following antibiotic administration. (biomedcentral.com)
  • Obviously, such an asymptomatic, persistent bacteremia with B. henselae represents an important factor for the spread of the pathogens via blood-sucking arthropods. (asm.org)
  • Inoculation of cats with salivary glands of infected ticks resulted in a B. henselae bacteremia ( 5 ). (asm.org)
  • antigens and bacteremia was confirmed by PCR amplification of B. henselae DNA from blood, and from a BAPGM blood agar plate subculture isolate. (biomedcentral.com)
  • Historically, persistent B. henselae bacteremia was not thought to occur in immunocompetent humans. (biomedcentral.com)
  • To our knowledge, this study provides preliminary evidence supporting the possibility of persistent B. henselae bacteremia in immunocompetent persons from Europe. (biomedcentral.com)
  • As the tick bites occurred three years prior to documentation of B. henselae bacteremia, the mode of transmission could not be determined. (biomedcentral.com)
  • Our ability to detect B. henselae in blood through culturing but not PCR suggests that the prevalence of infected cats with low bacteremia is very high, suggesting the need to develop faster, more sensitive detection assays. (biomedcentral.com)
  • Bartonella genotypes remained the same throughout the period of the acute bacteremia and in the recurring bacteremia as determined by the PCR assay. (lsu.edu)
  • Berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease" (PDF). (wikipedia.org)
  • Our group has already demonstrated that B. henselae -infected sickle cell disease mice present with hyperalgesia. (scielo.br)
  • Here, we present data on the prevalence of B. henselae and Lyme disease spirochetes in 654 questing ticks ( I. ricinus ) collected at four locations in Europe, suggesting that ticks might serve as potential vectors for the transmission of B. henselae to humans. (asm.org)
  • The natural reservoir of B. henselae are domestic cats and thus the disease is a zoonotic. (pathwaymedicine.org)
  • Here is where Bartonella henselae (the agent responsible for cat scrats disease) comes into play. (vibrant-itn.eu)
  • There is no practical in vivo model to study how the bacterium Bartonella henselae causes disease. (grantome.com)
  • There is a lot of disagreement over how often Bartonella causes disease in cats. (vetinfo.com)
  • Whether Bartonella can cause serious disease by itself in cats is still open to some debate. (vetinfo.com)
  • Since it doesn't appear likely at this time that it is possible to completely eliminate B. henselae from the blood stream of cats with antibiotics it probably doesn't make a lot of sense to try to treat all the cats and it might not even make sense to treat the cat with the positive titer, unless it seems like B. henselae is actually causing disease symptoms at the present time. (vetinfo.com)
  • Among 471 cat serum samples collected from 7 veterinary clinics in Kanagawa and Saitama Prefectures, 9.1% (41/471) and 8.7% (41/471) of cats harbored antibodies against Bartonella henselae and Toxoplasma gondii, respectively. (nii.ac.jp)
  • Serological tests were performed using B. henselae (Bh), Rickettsia rickettsii (Rr), Ehrlichia canis (Ec), Bartonella vinsonii subspecies berkhoffii (Bvb), Babesia canis (Bc) and Borrelia burgdorferi (Bb) antigens. (nih.gov)
  • Of the sick dogs that were seroreactive to B. henselae antigens, 40.6% were also seroreactive to Rr, 15.0% reactive to Bvb antigens, 14.8% reactive to Ec antigens, 1.8% reactive to Bc antigens and 1.75% reactive to Bb antigens. (nih.gov)
  • berkhoffii, E. canis or R. rickettsii did not cross react with B. henselae antigens, by IFA testing. (nih.gov)
  • We will employ In-Vivo Induced Antigen Technology (IVIAT) to identify Bartonella in-vivo induced antigens, which will allow us to evaluate their potential as diagnostic markers for canine bartonelloses. (akcchf.org)
  • antigens, and negative for Bartonella DNA amplification. (biomedcentral.com)
  • Thirteen of the seroreactive antigens were found to be differentially seroreactive between B. henselae type I and type II. (escholarship.org)
  • These interactions may be important initial steps leading to bacterial attachment and colonization that promote the establishment of B. henselae infections in vivo. (asm.org)
  • B. henselae Pap31 was originally described as a bacterial surface protein that is associated with the bacteriophage-like particle from B. henselae ( 6 ). (asm.org)
  • This fact makes Bartonella an interesting model to study the feasibility of blocking bacterial adherence to prevent and treat infections. (vibrant-itn.eu)
  • So, putting this together we have two possible participants in this bacterial adhesion process, BadA a bacterial protein from Bartonella and fibronectin a structural protein from the cellular environment. (vibrant-itn.eu)
  • Nine monoclonal antibodies derived from BALB/c mice immunized with B. henselae Houston-1 strain reacted only with strains Houston-1, 90-615, and SA2, and not with any other Bartonella strains. (asm.org)
  • The 16S-23S intergenic transcribed spacer region obtained from each porpoise was 99.8% similar to that of B. henselae strain San Antonio 2 (SA2), whereas both heme-binding phage-associated pap 31 gene sequences were 100% homologous to that of B. henselae SA2. (cdc.gov)
  • p26 gene sequences from four B. henselae strains, one B. koehlerae strain, and one B. clarridgeiae strain were cloned. (asm.org)
  • Alignment of the predicted amino acid sequences of P26 from B. henselae strain F1 (Bh F1), B. koehlerae (Bk), and B. clarridgeiae (Bc). (asm.org)
  • Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution. (escholarship.org)
  • Multi-locus sequence typing (MLST) identified the strain genotype as sequence type 5, commonly found zoonotic B. henselae strain in cats. (biomedcentral.com)
  • B. henselae ATCC 49882 strain was procured from American type culture collection, USA. (bvsalud.org)
  • B. henselae strain Berlin-1, isolated from bacillary angiomatosis lesions of a human immunodeficiency virus-infected patient, potently stimulated human umbilical cord vein endothelial cells (HUVEC), as determined by NF-kappaB activation and enhanced adhesion molecule expression. (unibas.ch)
  • In our hands, B. henselae Berlin-1 was substantially more active than the typing strain B. henselae ATCC 49882. (unibas.ch)
  • Here, we describe the discovery, characterization, and optimization of a liquid growth medium for Bartonella spp. (asm.org)
  • Molecular Characterization of Bartonella vinsonii subsp. (wikipedia.org)
  • In order to identify immunoreactive Bartonella henselae proteins, B. henselae antiserum from an experimentally infected cat was used to screen a B. henselae genomic DNA expression library. (asm.org)
  • Expression of p26 in Escherichia coli produced two proteins (26 and 27.5 kDa), both of which were reactive with feline anti- B. henselae antisera. (asm.org)
  • We report the development of a microarray comprised of proteins expressed from 96% (1433/1493) of the predicted ORFs encoded by the genome of the zoonotic pathogen Bartonella henselae. (escholarship.org)
  • We found that 7.3% of the B. henselae proteins on the microarray were seroreactive and that seroreactivity was not evenly distributed between predicted protein function or subcellular localization. (escholarship.org)
  • Through a type IV secretory system, B. henselae proteins are transported into the host cells. (diarect.com)
  • But is fibronectin the only structure important to support the adhesion or is Bartonella interacting with other human proteins? (vibrant-itn.eu)
  • The first is the VirB/VirD4 type IV secretion system that is responsible for delivering the bartonella effector proteins (Beps A-G) that act on endothelial cells in varying capacities. (grantome.com)
  • Exposure of HUVEC to purified B. henselae outer membrane proteins (OMPs), however, reproduced all aspects of endothelial cell activation. (unibas.ch)
  • The specific name henselae honors Diane Marie Hensel (b. 1953), a clinical microbiology technologist at University of Oklahoma Health Sciences Center, who collected numerous strains and samples of the infective agent during an outbreak in Oklahoma in 1985. (wikipedia.org)
  • Houston-1, 90-615, and SA2 strains showed the same patterns in SDS-PAGE, but they differed from the patterns of B. henselae isolates URBHLLY8, URBHLIE9, Cat6, Fizz, and CAL-1. (asm.org)
  • Study of 22 additional strains of B. henselae isolated from French bacteremic cats demonstrated that they all belong to one or the other of the proposed serotype or genotype. (asm.org)
  • The authors found that two isolates of B. henselae , from a patient with endocarditis and a patient with CSD, were genetically different from all previously isolated strains by sequence analysis of the 16S rRNA-encoding gene. (asm.org)
  • A subset of 31 of these cats also had whole blood collected to tentatively isolate Bartonella strains. (ajtmh.org)
  • We selected in vitro erythromycin-resistant strains of Bartonella henselae . (asm.org)
  • For B. henselae , potential mechanisms of resistance to macrolides are not known, and the objective of the present study was to select in vitro erythromycin-resistant (ER) strains to examine the molecular mechanism of resistance. (asm.org)
  • The seven strains of B. henselae used here are described in Table 1 . (asm.org)
  • Improvements in the techniques used to isolate B. henselae and new methods for the identification and detection of the organism have enabled further clinical manifestations of infections to be determined. (asm.org)
  • We report detection of Bartonella henselae DNA in blood samples from 2 harbor porpoises ( Phocoena phocoena ). (cdc.gov)
  • We report real-time PCR detection of B. henselae SA2 DNA in porpoise blood samples. (cdc.gov)
  • In an effort to overcome limitations associated with the molecular detection and isolation of Bartonella spp. (biomedcentral.com)
  • In addition, utilization of the BAPGM enrichment blood culture platform has facilitated the isolation or molecular detection of other Bartonella spp. (biomedcentral.com)
  • Improvement of Bartonella henselae DNA Detection in Cat Blood Samples by Combining Molecular and Culture Methods. (bvsalud.org)
  • Detection of a Bartonella henselae -specific DNA target in DNA isolated from the blood and cerebrospinal fluid (CSF) of naturally infected individuals (case reports) before and after antimicrobial therapy. (jamanetwork.com)
  • Pathogenesis of Bartonella Henselae in the Domestic Cat: Use of a PCR-based Assay for the Detection and Differentiation of B. Henselae Genotype I and Genotype II in Chronically Infected Cats. (lsu.edu)
  • Cats do have the capacity to spread Bartonella henselae to humans. (medic8.com)
  • There have been reports of Bartonella henselae found inside fleas, however, there have been no instances of flea bites causing CSD in humans. (medic8.com)
  • In contrast to the large body of literature regarding Bartonella henselae in humans and cats, there is little information about B. henselae as an infectious agent in dogs. (nih.gov)
  • Humans become infected with B. henselae by direct or indirect contact with kittens or cats harboring the organism. (canada.ca)
  • Taken together, our data indicate that ticks might serve as a vector for the transmission of B. henselae to humans. (asm.org)
  • B. henselae is commonly transmitted when humans are scratched or bitten by cats or dogs [ 2 - 4 ]. (kjim.org)
  • Sequences of glt A gene were trimmed using BioEdit software and then compared with the sequences of the same gene from B. henselae isolated from cats and humans in GenBank database. (iranjournals.ir)
  • Despite this prevalence, we are unaware of reports of Bartonella culturing from infected humans or cats in Croatia or elsewhere in southeast Europe. (biomedcentral.com)
  • Bartonella henselae is a zoonotic agent in which the domestic cat serves as the natural reservoir, and humans acquire potentially serious infections associated with this microorganism. (lsu.edu)
  • B. henselae is of the Bartonellaceae family, and appear as fastidious aerobic, short, Gram-negative rods (0.2 to 0.6 µm by 0.5 to 1.0 µm) Footnote 3 , Footnote 4 . (canada.ca)
  • Bartonella is fastidious and fragile organism and should be handled carefully. (bvsalud.org)
  • we suggest that bartonella serology is included in the baseline tests performed on children with prolonged fever even in the absence of contact with cats in countries where bartonellosis is prevalent. (hindawi.com)
  • Due to the paucity of information regarding the B. henselae serology in dogs, we performed a cross-sectional serosurvey using B. henselae antigen in order to compare the seroprevalence between sick and healthy dogs from the south-eastern USA. (nih.gov)
  • Serology reagents intended to detect antibodies to Bartonella henselae, a rod-shaped bacterium of the family Bartonellaceae. (ophthalmologymanagement.com)
  • Using sequence differences in a portion of the I 6S rRNA gene between B. henselae genotype I, and B. henselae genotype II, a nested polymerase chain reaction (nPCR) was designed and used to investigate various phases of feline bartonellosis. (lsu.edu)
  • Angiomatous proliferation and granulomatous reactions, severe anemia and cholestatic hepatitis are examples of the wide spectrum of clinical manifestations associated with Bartonella sp. (scielo.br)
  • Does coinfection of Bartonella henselae and FIV induce clinical disorders in cats? (nih.gov)
  • It was found that Bartonella henselae (B. henselae) may induce clinical disorders in cats in natural conditions from a comparison of the serological status for B. henselae with the serostatus for feline immunodeficiency virus (FIV) and several clinical characteristics in 170 domestic cats. (nih.gov)
  • The incidence of clinical characteristics were compared among four cat groups distinguished by the reactivity of sera against B. henselae and FIV. (nih.gov)
  • Moreover, the sequences of the macrolide resistance target genes of 15 B. henselae PCR-positive lymph nodes from patients with CSD ( 18 ) have been examined to look for possible natural resistance in clinical isolates. (asm.org)
  • To describe the ocurrence of Bartonella -associated neuroretinitis secondary to non-feline pet exposure, we retrospectively reviewed medical records and imaging from patients with a clinical and serologic diagnosis of Bartonella henselae (BH). (mysciencework.com)
  • The presence of B. henselae in these patients was deduced from the clinical presentation, epidemiological history and presence of anti- B. henselae antibodies based on an indirect immunofluorescence assay (IFA). (biomedcentral.com)
  • 2010) showed molecular evidence of perinatal transmission of Bartonella vinsonii subsp. (scielo.br)
  • Each family member was tested for serological evidence of Bartonella exposure using B. vinsonii subsp. (biomedcentral.com)
  • including Bartonella vinsonii subsp. (biomedcentral.com)
  • The same relation was also observed for the incidence of gingivitis among the 4 cat groups, suggesting that coinfection of B. henselae and FIV may be associated with gingivitis and lymphadenopathy in cats. (nih.gov)
  • 13 ] reported that 38.7% of patients with lymphadenopathy showed high titers of B. henselae immunoglobulin G (IgG) (≥ 1:128). (kjim.org)
  • B. henselae is likely to be present throughout the country, since a survey of serum samples from 268 Croatian patients with lymphadenopathy showed that 37.7% patients had IgG antibodies against B. henselae [ 9 ]. (biomedcentral.com)
  • At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. (medic8.com)
  • The study of 16S rRNA gene sequences of all isolates of Bartonella henselae obtained in our laboratory and others from human patients or cats has revealed two genotypes according to the sequence of the 16S rRNA gene. (asm.org)
  • 34 ) identified five different fingerprint profiles from 17 isolates of B. henselae isolated from cats and from tissue and blood of human immunodeficiency virus-infected patients and patients with CSD. (asm.org)
  • Bartonella henselae and B. clarridgeiae were isolated from 19 (61%) of these cats. (ajtmh.org)
  • Bartonella henselae type I was isolated from 17 (89%) of the 19 culture-positive cats. (ajtmh.org)
  • Six cats (31%) were infected with B. clarridgeiae, of which four were coinfected with B. henselae. (ajtmh.org)
  • When tested by enzyme immunoassay (EIA), 67 cats (62.6%) had antibodies to B. henselae and 71 cats (66.4%) had antibodies to B. clarridgeiae. (ajtmh.org)
  • Cats are a confirmed reservoir host of B. henselae transmitting the pathogen by cat scratches or bites. (asm.org)
  • B. henselae was detected in the peripheral blood of a wide range of mammals including domestic (e.g., cats, dogs, and horses) and wild animals (e.g., porpoise, lions, cheetahs, and wild felids). (asm.org)
  • Publications] Maruyama, S.他5名: 'Prevalence of Bartonella henselae, Bartonella clarridgeiae and the 16SrRNA Gene Types of Bartonella henselae among Pet Cats in Japan'J.Vet.Med.Sci. (nii.ac.jp)
  • Publications] Maruyama, S.他10名: 'Seroprevalence of Bartonella henselae and Toxoplasma gondii infections among pet cats in Kanagawa and Saitama Prefectures'J.Vet.Med.Sci. (nii.ac.jp)
  • Participants who had raised cats showed 22.2% seropositivity against B. henselae , and those with no experience with cats showed 13.7% seroprevalence ( p = 0.17). (kjim.org)
  • Participants who had cats as pets or been scratched by cats, showed 9.8% seropositivity against B. henselae (IFA titer ≥ 1:256). (kjim.org)
  • Approximately, 16% to 43% of specimens (i.e., blood, nail, and saliva) from dogs and cats were positive for B. henselae , as confirmed by PCR [ 3 ]. (kjim.org)
  • In conclusion, findings of this study showed the prevalence of B. henselae in Iranian cats which is important due to its public health issues, especially for the immunocompromised pet owners. (iranjournals.ir)
  • Cats can get infected with B. henselae from flea bites and flea dirt (droppings) getting into their wounds. (cdc.gov)
  • The CDC estimates that about 40 percent of all cats bring Bartonella henselae at some time in their life. (ehealthglobalhealth.com)
  • Bartonella henselae LSU 16 genotype II, Bartonella henselae Baby genotype II, Bartonella henselae 87--66 genotype I, and Bartonella henselae Houston-1 genotype I were used in this study to infect cats. (lsu.edu)
  • Of the twenty-three cats examined, Bartonella DNA was detected in various tissues from 10 of the 23 cats. (lsu.edu)
  • The spleen of nine of the 10 cats was positive for Bartonella DNA. (lsu.edu)
  • RNA expression analysis using the RT-PCR assay with primers specific for the 16S rRNA and the citrate synthase gene (gltA) of Bartonella detected no Bartonella RNA expression in the tissue of infected cats. (lsu.edu)
  • B. henselae genotype I was not detected in any of the infected cats. (lsu.edu)
  • Sometimes, yes, cats can spread B. henselae to people. (lymphedemapeople.com)
  • About 40% of cats carry B. henselae at some time in their lives. (lymphedemapeople.com)
  • To perform a serological survey for Bartonella henselae among cats in Chile. (conicyt.cl)
  • One of my cats has been diagnosed with Bartonella (level 4). (vetinfo.com)
  • I do not believe that the ability of any antibiotic or antibiotic combination to completely clear B. henselae from the blood stream of cats has been proven at this time, but I could be wrong. (vetinfo.com)
  • To determine whether Bartonella henselae is present in questing Ixodes ricinus ticks, we analyzed the prevalence of B. henselae DNA among tick stages compared to the prevalence of DNA from Borrelia burgdorferi sensu lato, the pathogen most frequently transmitted by ticks. (asm.org)
  • Nevertheless, controversial data about the prevalence of Bartonella spp. (asm.org)
  • Despite this prevalence, we are unaware of reports of Bartonella sp. (biomedcentral.com)
  • PCR-based RFLP analysis of the 16S-23S rRNA intergenic spacer region using Alu I and Hae III demonstrated seven composite RFLP types in 11 B. henselae isolates from patients with BA, septicemia, and parenchymal bacillary peliosis ( 26 ). (asm.org)
  • The BAPGM platform consists of PCR amplification of Bartonella DNA from the patient's extracted blood and serum samples before, and after BAPGM enrichment culture and from isolates, if obtained, following subculture of pre-enriched samples onto blood agar plates. (biomedcentral.com)
  • The Gram-negative bacterium Bartonella henselae (Bh) is an emerging zoonotic pathogen that has been associated with a variety of human diseases including bacillary angiomatosis which is characterized by vasoproliferative tumor-like lesions on the skin and internal organs of some immunosuppressed individuals. (usf.edu)
  • Angelakis E, Raoult D. Pathogenicity and treatment of Bartonella infections. (wikipedia.org)
  • Severe anemia and cholestatic hepatitis are associated with bartonella infections. (scielo.br)
  • So we now know that Lyme, Babesia and Bartonella are in the US (at least) blood supply - and people wonder how come there are so many people with these infections? (healingwell.com)
  • Bartonella henselae wound-associated infections suggest involvement of extracellular matrix molecules in adhesion and invasion. (asm.org)
  • Skin manifestations of Bartonella infections. (springer.com)
  • Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma. (abcam.com)
  • Several virulence factors associated with Bartonella -induced pathogenesis have been characterized. (usf.edu)
  • The purpose of this research is to contribute to the understanding of the pathogenesis of B. henselae in the domestic cat using a molecular approach. (lsu.edu)
  • on solid media has limited diagnostic (e.g., primary isolation) and experimental (e.g., analyses of B. henselae pathogenicity) approaches. (asm.org)
  • B. henselae pathogenicity and might also be evaluated for its use in the primary cultivation of Bartonella spp. (asm.org)
  • To our knowledge, this is the first time that a B. henselae organism has been visualized in and amplified from a striae lesion. (biomedcentral.com)
  • It was later called Bartonella bacilliformis . (cdc.gov)
  • Bartonella bacilliformis (Strong et al. (atcc.org)
  • Bacteriostatic antibiotics are not able to easily get through to intracellular Bartonella, so they are not recommended. (wikipedia.org)
  • Bacillary angiomatosis is another pathological condition which results due to the bacterium B. Henselae in which there is the formation of vascular lesions on the skin, lymph nodes, brain and the bones. (studentshare.org)
  • B. henselae is a Gram-negative rod. (wikipedia.org)
  • Download file to see previous pages B. Henselae comes from the rickettsiaceae family and has been identified as a gram negative bacterium. (studentshare.org)
  • However, their diagnosis of B henselae is questionable. (jamanetwork.com)
  • The diagnosis of B henselae is based on the IgG titers of 1:128 and therapeutic response to moxifloxacin. (jamanetwork.com)
  • Recently, a more sensitive isolation approach was developed by using Bartonella alpha proteobacteria growth medium (BAPGM) followed by real-time polymerase chain reaction (PCR). (cdc.gov)
  • were used to test formalin-fixed, paraffin embedded brain tissue, patient blood specimens and Bartonella alpha Proteobacteria growth medium (BAPGM) enrichment blood cultures. (biomedcentral.com)
  • from animals and immunocompetent human patients, our laboratory developed a novel diagnostic platform based on biochemical optimization of a modified insect-cell culture liquid medium ( Bartonella alpha Proteobacteria Growth Medium or BAPGM) [ 13 ]. (biomedcentral.com)
  • We hypothesized that even immunocompetent mice infected by B. henselae would show an increased and persistent mechanical sensitivity. (scielo.br)
  • The persistent Bartonella DNA detected in tissue was B. henselae genotype II. (lsu.edu)
  • Apart from typical CSD, B. henselae has been recognized as a rare cause of fever of unknown origin (FUO) [ 1 ]. (hindawi.com)
  • Moreover, immunohistochemistry analysis with anti-Bartonella showed that the number of positive cells per field decreased of at least 50% in the liver (20±4 vs 50±8), aorta (5±1 vs 10±2) and spleen (25±3 vs 40±6) sections of mice coinfected compared to mice infected only with B. henselae. (unicampania.it)
  • antigen, but B. henselae DNA was amplified from several blood and serum samples, from BAPGM enrichment blood culture, and from a cutaneous striae biopsy. (biomedcentral.com)
  • Recently, ticks ( I. ricinus ) were experimentally infected with B. henselae . (asm.org)
  • Analysis of 36-kilodalton protein (PapA) associated with the bacteriophage particle of Bartonella henselae. (nih.gov)
  • A) Coomassie blue-stained SDS-polyacrylamide gel of B. henselae rP26 protein preparation. (asm.org)
  • B and C) Western blots of B. henselae rP26 protein preparation probed with a feline antiserum (B) or with a murine rP26 hyperimmune serum (C). Arrows on the right show the locations of the preprotein (PP) and the mature rP26 (P26). (asm.org)
  • Taken together, these data suggest that Pap31 is an Fn-binding protein mediating the B. henselae -host interaction(s), and they implicate the 13 FnIII repeat module as an important binding site for this adhesin on the Fn molecule. (asm.org)
  • Previous research has described that by removing just one instrument from its toolbox, a protein called BadA, Bartonella reduces significantly its ability to attach to human cells. (vibrant-itn.eu)
  • To address this concern we plan to infect embryos from zebra fish with Bartonella henselae to study the infectious process. (grantome.com)
  • Human coinfection with Bartonella henselae and two hemotropic mycoplasma variants resembling Mycoplasma ovis. (semanticscholar.org)
  • article{Sykes2010HumanCW, title={Human coinfection with Bartonella henselae and two hemotropic mycoplasma variants resembling Mycoplasma ovis. (semanticscholar.org)
  • Positive samples for B. henselae were characterized by polymerase chain reaction (PCR) and sequencing. (iranjournals.ir)
  • The arrow indicates a B henselae -specific polymerase chain reaction (PCR) product of 279 base pairs (bp). (jamanetwork.com)
  • The B. henselae isolate was grown on different blood agar plates and its identity was confirmed based on polymerase chain reaction ( PCR) amplification of 16S ribosomal deoxyribonucleic acid (16S rDNA) and sequencing. (biomedcentral.com)
  • K. Puri, A. J. Kreppel, and E. P. Schlaudecker, " Bartonella osteomyelitis of the acetabulum: case report and review of the literature," Vector-Borne and Zoonotic Diseases , vol. 15, no. 8, pp. 463-467, 2015. (hindawi.com)
  • berkhoffii and B. henselae to a child 7 . (scielo.br)
  • Some patients had hepatosplenic involvement, myalgia, and arthritis after exposure to B. henselae. (wikipedia.org)
  • Investigators in The Netherlands ( 2 ) also demonstrated two restriction fragment length polymorphism (RFLP) patterns of B. henselae DNA in samples from CSD patients. (asm.org)
  • Identification of Bartonella henselae in an aborted equine fetus. (abcam.com)
  • Because of the rapid discovery of new, pathogenic Bartonella spp. (biomedcentral.com)
  • Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 18kDa. (prospecbio.com)
  • Serum B. henselae IgG antibodies were detected in 10.1% of healthy dogs and in 27.2% of sick dogs. (nih.gov)
  • Serum samples from 300 healthy participants were analyzed using an immunoglobulin G immunof luorescence assay (IFA) for B. henselae isolated in Korea. (kjim.org)