Bartonella henselae: A species of gram-negative bacteria that is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY). This organism can also be a cause of CAT-SCRATCH DISEASE in immunocompetent patients.Bartonella: A genus of gram-negative bacteria characteristically appearing in chains of several segmenting organisms. It occurs in man and arthropod vectors and is found only in the Andes region of South America. This genus is the etiologic agent of human bartonellosis. The genus Rochalimaea, once considered a separate genus, has recently been combined with the genus Bartonella as a result of high levels of relatedness in 16S rRNA sequence data and DNA hybridization data.Bartonella Infections: Infections by the genus BARTONELLA. Bartonella bacilliformis can cause acute febrile anemia, designated Oroya fever, and a benign skin eruption, called verruga peruana. BARTONELLA QUINTANA causes TRENCH FEVER, while BARTONELLA HENSELAE is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY) and is also one of the causes of CAT-SCRATCH DISEASE in immunocompetent patients.Cat-Scratch Disease: A self-limiting bacterial infection of the regional lymph nodes caused by AFIPIA felis, a gram-negative bacterium recently identified by the Centers for Disease Control and Prevention and by BARTONELLA HENSELAE. It usually arises one or more weeks following a feline scratch, with raised inflammatory nodules at the site of the scratch being the primary symptom.Angiomatosis, Bacillary: A reactive vascular proliferation that is characterized by the multiple tumor-like lesions in skin, bone, brain, and other organs. Bacillary angiomatosis is caused by infection with gram-negative Bartonella bacilli (such as BARTONELLA HENSELAE), and is often seen in AIDS patients and other IMMUNOCOMPROMISED HOSTS.Bartonella quintana: A species of gram-negative bacteria in which man is the primary host and the human body louse, Pediculus humanus, the principal vector. It is the etiological agent of TRENCH FEVER.Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.Cats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Trench Fever: An intermittent fever characterized by intervals of chills, fever, and splenomegaly each of which may last as long as 40 hours. It is caused by BARTONELLA QUINTANA and transmitted by the human louse.Bartonella bacilliformis: The type species of the genus BARTONELLA, a gram-negative bacteria found in humans. It is found in the mountain valleys of Peru, Ecuador, and Southwest Columbia where the sandfly (see PHLEBOTOMUS) vector is present. It causes OROYA FEVER and VERRUGA PERUANA.Siphonaptera: An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.Peliosis Hepatis: A vascular disease of the LIVER characterized by the occurrence of multiple blood-filled CYSTS or cavities. The cysts are lined with ENDOTHELIAL CELLS; the cavities lined with hepatic parenchymal cells (HEPATOCYTES). Peliosis hepatis has been associated with use of anabolic steroids (ANABOLIC AGENTS) and certain drugs.Bartonellaceae: A family of small gram-negative bacteria whose organisms are parasites of erythrocytes in man and other vertebrates and the etiologic agents of several diseases.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Ctenocephalides: A genus of FLEAS in the family Pulicidae. It includes the cat flea (Ctenocephalides felis), one of the most common species on earth.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Grenada: An island of the West Indies. Its capital is St. George's. It was discovered in 1498 by Columbus who called it Concepcion. It was held at different times by the French and the British during the 18th century. The British suppressed a native uprising in 1795. It was an associate state of Great Britain 1967-74 but became an independent nation within the British Commonwealth in 1974. The original name referred to the Feast of the Immaculate Conception but it was later renamed for the Spanish kingdom of Granada. (From Webster's New Geographical Dictionary, 1988, p467 & Room, Brewer's Dictionary of Names, 1992, p219)Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.Disease Reservoirs: Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.Lymphatic Diseases: Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Ectoparasitic Infestations: Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.Seroepidemiologic Studies: EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.Fluorescent Antibody Technique, Indirect: A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labeled with fluorescein-conjugated anti-immunoglobulin antibody. (From Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)Rickettsieae: A tribe of gram-negative bacteria of the family RICKETTSIACEAE whose organisms are found in arthropods and are pathogenic for man and certain other vertebrate hosts.Panuveitis: Inflammation in which both the anterior and posterior segments of the uvea are involved and a specific focus is not apparent. It is often severe and extensive and a serious threat to vision. Causes include systemic diseases such as tuberculosis, sarcoidosis, and syphilis, as well as malignancies. The intermediate segment of the eye is not involved.Leukemia, Feline: A neoplastic disease of cats frequently associated with feline leukemia virus infection.Rickettsiaceae: A family of small, gram-negative organisms, often parasitic in humans and other animals, causing diseases that may be transmitted by invertebrate vectors.Tick-Borne Diseases: Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.DNA, Ribosomal Spacer: The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers).Immunocompetence: The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen.Behavioral Medicine: The interdisciplinary field concerned with the development and integration of behavioral and biomedical science, knowledge, and techniques relevant to health and illness and the application of this knowledge and these techniques to prevention, diagnosis, treatment, and rehabilitation.Adolescent Medicine: A branch of medicine pertaining to the diagnosis and treatment of diseases occurring during the period of ADOLESCENCE.Perinatology: The branch of medicine dealing with the fetus and infant during the perinatal period. The perinatal period begins with the twenty-eighth week of gestation and ends twenty-eight days after birth. (From Dorland, 27th ed)Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Phocoena: A genus of PORPOISES, in the family Phocoenidae, comprised of several species. They frequent coastal waters, bays, estuaries, and the mouths of large rivers.Porpoises: Mammals of the family Phocoenidae comprising four genera found in the North Pacific Ocean and both sides of the North Atlantic Ocean and in various other seas. They differ from DOLPHINS in that porpoises have a blunt snout and a rather stocky body while dolphins have a beak-like snout and a slender, streamlined body. They usually travel in small groups. (From Walker's Mammals of the World, 5th ed, pp1003-4)Material Safety Data Sheets: Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures.Hazardous Substances: Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.Rickettsia prowazekii: A species of gram-negative, aerobic bacteria that is the etiologic agent of epidemic typhus fever acquired through contact with lice (TYPHUS, EPIDEMIC LOUSE-BORNE) as well as Brill's disease.Typhus, Epidemic Louse-Borne: The classic form of typhus, caused by RICKETTSIA PROWAZEKII, which is transmitted from man to man by the louse Pediculus humanus corporis. This disease is characterized by the sudden onset of intense headache, malaise, and generalized myalgia followed by the formation of a macular skin eruption and vascular and neurologic disturbances.Rickettsia: A genus of gram-negative, aerobic, rod-shaped bacteria often surrounded by a protein microcapsular layer and slime layer. The natural cycle of its organisms generally involves a vertebrate and an invertebrate host. Species of the genus are the etiological agents of human diseases, such as typhus.Fibronectins: Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Metabolic Phenomena: The CHEMICAL PROCESSES that occur within the cells, tissues, or an organism and related temporal, spatial, qualitative, and quantitative concepts.Peptide Nucleic Acids: DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.Metabolic Engineering: Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.Industrial Microbiology: The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)

Cat-scratch disease with paravertebral mass and osteomyelitis. (1/275)

The case of a 9-year-old girl with cat-scratch disease (CSD) complicated by development of a paravertebral mass and osteomyelitis is presented. Following multiple scratches and inguinal lymphadenopathy, she developed back pain, and imaging demonstrated a paravertebral mass with evidence of osteomyelitis involving vertebra T9. The diagnosis was made on the basis of detection of Bartonella henselae by use of molecular techniques on an aspirate from the vertebral column and supportive serology for infection with B. henselae. Eleven other cases of this unusual manifestation associated with CSD have been reported in the literature and are reviewed. The patient was treated with gentamicin, followed by rifampicin and trimethoprim-sulfamethoxazole, orally and made a favorable recovery over 7 months. This is comparable with other case reports, regardless of the choice of antibiotic therapy. CSD in immunocompetent hosts is not always self-limiting, and tissues beyond the lymph nodes can be involved.  (+info)

Detection of Bartonella henselae DNA by two different PCR assays and determination of the genotypes of strains involved in histologically defined cat scratch disease. (2/275)

Cat scratch disease (CSD) is a common cause of subacute regional lymphadenopathy, not only in children but also in adults. Serological and molecular studies demonstrated that Bartonella henselae is the etiologic agent in most cases of CSD. Amplification of B. henselae DNA in affected tissue and detection of antibodies to B. henselae are the two mainstays in the laboratory diagnosis of CSD. We designed a retrospective study and investigated formalin-fixed, paraffin-embedded lymph nodes from 60 patients (25 female, 35 male) with histologically suspected CSD by PCR amplification. The sensitivities of two different PCR assays were compared. The first primer pair amplified a 296-bp fragment of the 16S rRNA gene in 36 of the 60 samples, corresponding to a sensitivity of 60%. The second primer pair amplified a 414-bp fragment of the htrA gene in 26 of the 60 lymph nodes, corresponding to a sensitivity of 43.3%. Bartonella DNA could be detected in a total of 39 (65%) of the 60 lymph nodes investigated. However, histopathologic findings are typical but not specific for CSD and cannot be considered as a "gold standard" for diagnosis of CSD. The sensitivity of the PCR assays increased from 65 to 87% if two criteria (histology and serology) were used in combination for diagnosis of CSD. Two genotypes (I and II) of B. henselae are described as being involved in CSD. Genotype I was found in 23 (59%) and genotype II was found in 9 (23%) of the 39 PCR-positive lymph nodes. Seven (18%) lymph nodes were negative in both type-specific PCR assays. Thirty (50%) of our 60 patients were younger than 20 years old (15 were younger than 10 years), 20 (33%) were between 21 and 40 years old, and 10 (17%) patients were between 41 and 84 years old. Our data suggest that detection of Bartonella DNA in patients' samples might confirm the histologically suspected diagnosis of CSD.  (+info)

Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). (3/275)

Bartonella quintana and Bartonella henselae are fastidious gram-negative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. During a 5-year period, we received 2,043 samples for culture of Bartonella sp. We found Bartonella sp. to be the etiologic agent in 38 cases of endocarditis, 78 cases of cat scratch disease, 16 cases of bacteremia in homeless people, and 7 cases of bacillary angiomatosis. We correlated the results of positive cultures with the clinical form of the disease, type of sample, culture procedure, PCR-based genomic detection, and antibody determination. Seventy-two isolates of B. quintana and nine isolates of B. henselae from 43 patients were obtained. Sixty-three of the B. quintana isolates and two of the B. henselae isolates, obtained from patients with no prior antibiotic therapy, were stably subcultured. The sensitivity of culture was low when compared with that of PCR-based detection methods in valves of patients with endocarditis (44 and 81%, respectively), skin biopsy samples of patients with bacillary angiomatosis (43 and 100%, respectively), and lymph nodes of cat scratch disease (13 and 30%, respectively). Serological diagnosis was also more sensitive in cases of endocarditis (97%) and cat scratch disease (90%). Among endocarditis patients, the sensitivity of the shell vial culture assay was 28% when inoculated with blood samples and 44% when inoculated with valvular biopsy samples, and the sensitivity of both was significantly higher than that of culture on agar (5% for blood [P = 0.045] and 4% for valve biopsy samples [P < 0.0005]). The most efficient culture procedure was the subculture of blood culture broth into shell vials (sensitivity, 71%). For patients with endocarditis, previous antibiotic therapy significantly affected results of blood culture; no patient who had been administered antibiotics yielded a positive blood culture, whereas 80% of patients with no previous antibiotic therapy yielded positive blood cultures (P = 0.0006). Previous antibiotic therapy did not, however, prevent isolation of Bartonella sp. from cardiac valves but did prevent the establishment of strains, as none of the 15 isolates from treated patients could be successfully subcultured. For the diagnosis of B. quintana bacteremia in homeless people, the efficiency of systematic subculture of blood culture broth onto agar was higher than that of direct blood plating (respective sensitivities, 98 and 10% [P < 10(-7)]). Nevertheless, both procedures are complementary, since when used together their sensitivity reached 100%. All homeless people with positive blood cultures had negative serology. The isolation rate of B. henselae from PCR-positive lymph nodes, in patients with cat scratch disease, was significantly lower than that from valves of endocarditis patients and skin biopsy samples from bacillary angiomatosis patients (13 and 33%, respectively [P = 0.084]). In cases of bacillary angiomatosis for which an agent was identified to species level, the isolation rate of B. henselae was lower than the isolation rate of B. quintana (28 and 64%, respectively [P = 0.003]). If culture is to be considered an efficient tool for the diagnosis of several Bartonella-related diseases, methodologies need to be improved, notably for the recovery of B. henselae from lymph nodes of patients with cat scratch disease.  (+info)

Acute clinical disease in cats following infection with a pathogenic strain of Bartonella henselae (LSU16). (4/275)

Bartonella henselae is the causative agent of human cat scratch disease as well as several serious sequelae of infections, including bacillary angiomatosis and bacillary peliosis. Conflicting reports describe the pathogenesis of B. henselae in the cat. In this study, we characterized a strain of B. henselae termed LSU16. This strain was isolated on rabbit blood agar from a naturally infected 10-month-old female cat during a recurrent episode of bacteremia. The bacterial species was confirmed by PCR-restriction fragment length polymorphism analysis. Nine cats were infected intradermally with 5 x 10(7) CFU of LSU16, and clinical signs, antibody responses, and bacteremia were monitored. All nine cats developed raised, erythematous areas at the site of inoculation within 72 h postinoculation; the swelling peaked at 14 days postinfection and was not palpable by 28 days postinfection. Fever developed in all nine cats between 6 and 16 days postinfection and lasted for 1 to 8 days. Between 6 and 16 days postinfection, all nine cats experienced lethargy which persisted 5 to 18 days. Seven of nine cats were bacteremic by day 7, and all nine cats had become bacteremic by 14 days postinfection. Bacteremia peaked at 14 to 28 days postinfection in all cats. In six of the nine infected cats, bacterial numbers reached nondetectable levels during the 7th week postinfection; however, a single animal maintained bacteremia to 18 weeks postinfection. All nine cats developed strong antibody responses to B. henselae, as determined by Western blot analysis and enzyme-linked immunosorbent assay. Subsequently, three naive cats were injected intradermally with blood from cats infected with LSU16 from a pure culture, and five naive cats were injected with feces from fleas which had been feeding on cats infected with a pure culture of LSU16. These cats developed signs similar to those described in the previous experiment and were euthanized at 5 weeks postinfection. We conclude that B. henselae LSU16 is a virulent strain of B. henselae in cats and propose that the virulence of B. henselae in cats is strain dependent.  (+info)

Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from The Philippines. (5/275)

One hundred seven domestic cats from The Philippines were serologically tested to establish the prevalence of Bartonella infection. A subset of 31 of these cats also had whole blood collected to tentatively isolate Bartonella strains. Bartonella henselae and B. clarridgeiae were isolated from 19 (61%) of these cats. Bartonella henselae type I was isolated from 17 (89%) of the 19 culture-positive cats. Six cats (31%) were infected with B. clarridgeiae, of which four were coinfected with B. henselae. Sixty-eight percent (73 of 107) and 65% (70 of 107) of the cats had antibodies to B. henselae and B. clarridgeiae, respectively, detected by an immunofluorescence antibody (IFA) test at a titer > or = 1:64. When tested by enzyme immunoassay (EIA), 67 cats (62.6%) had antibodies to B. henselae and 71 cats (66.4%) had antibodies to B. clarridgeiae. Compared with the IFA test, the B. henselae EIA had a sensitivity of 90.4% and a specificity of 97%, with positive and negative predictive values of 98.5% and 82.5%, respectively. Similarly, the B. clarridgeiae EIA had a sensitivity of 97% and a specificity of 92% specificity, with positive and negative predictive values of 95.8% and 94.4%, respectively. The presence of antibodies to Bartonella was strongly associated with flea infestation. Domestic cats represent a large reservoir of Bartonella infection in the Philippines.  (+info)

Presumed ocular bartonellosis. (6/275)

BACKGROUND: The spectrum of diseases caused by Bartonella henselae continues to expand and ocular involvement during this infection is being diagnosed with increasing frequency. METHODS: The clinical features and visual prognosis for 13 patients with intraocular inflammatory disease and laboratory evidence of bartonellosis were investigated. There were nine patients with neuroretinitis and four with panuveitis with positive antibody titres against B henselae determined by an enzyme immunoassay (IgG exceeding 1:900 and/or IgM exceeding 1:250). RESULTS: Positive IgG levels were found for eight patients and positive IgM levels for five. Despite animal exposure of 10 patients, only two (IgG positive) cases had systemic symptoms consistent with the diagnosis of cat scratch disease. Pathological fluorescein leakage of the optic disc was observed in all affected eyes. At 6 months' follow up, 3/18 (17%) affected eyes had a visual acuity of less than 20/100, owing to optic disc atrophy and cystoid macular oedema. 12 patients (17 eyes) were treated with antibiotics; visual acuity improved two or more Snellen lines for 9/17 (53%) eyes. CONCLUSIONS: The possibility of B henselae infection should be considered in patients with neuroretinitis and panuveitis (especially in cases with associated optic nerve involvement) even in the absence of systemic symptoms typical for cat scratch disease.  (+info)

Identification of Bartonella-specific immunodominant antigens recognized by the feline humoral immune system. (7/275)

The seroreactivities of both naturally and experimentally infected cats to Bartonella henselae was examined. Serum samples collected weekly from nine cats experimentally infected with B. henselae LSU16 were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The magnitude and isotype of the antibody response were investigated by ELISA. Western blot analysis allowed the identification of at least 24 Bartonella-specific antigens recognized by the cats during infection. Antibody titers to specific antigens, as determined by Western blot analysis, ranged from 10 to 640 and varied among the different antibody-antigen interactions. Absorption of sera from an experimentally infected cat, using whole cells and cell lysates of various Bartonella species and other bacteria that commonly colonize cats, supported the identification of those Bartonella-specific antigens recognized by the experimentally infected cats. Furthermore, a number of possible species- and type-specific antigens were identified. Finally, sera obtained from cats at local animal shelters were screened for the presence of antibodies directed against the Bartonella-specific bands identified in the experimentally infected cats. A number of Bartonella-specific antigens have been identified to which strong antibody responses are generated in both experimentally and naturally infected cats, some of which may be useful in diagnosing species- and/or type-specific infections. In addition, the results from these experiments will lead to the development of monoclonal antibodies targeted against those genus-, species-, and type-specific antigens.  (+info)

Characterization of Bartonella henselae-specific immunity in BALB/c mice. (8/275)

BALB/c mice were inoculated with Bartonella henselae by both systemic and mucosal routes. Culture analysis of tissues from mice infected intraperitoneally with a high dose of B. henselae yielded positive results 24 hr after infection. However, culture analysis of blood taken between 6 hr and 7 days after infection from groups receiving live B. henselae were negative. Following intraperitoneal infection, B. henselae was detected by polymerase chain reaction in liver and mesenteric lymph nodes by 6 hr and up to 7 days after infection in liver, kidney and spleen tissue. Enzyme-linked immunosorbent assay (ELISA) of serum samples collected as early as 13 days after infection indicated humoral immune responses to B. henselae. Specific humoral responses remained through week 6. Analysis of faecal samples revealed induction of B. henselae-specific immunoglobulin A by day 28 after infection. In addition, B. henselae-specific cellular responses were indicated by a positive delayed-type hypersensitivity and a T helper 1 (Th1) (CD4+ T cell)-type cytokine response following in vitro stimulation of splenocytes. The significance and implications of these data in relation to B. henselae infections are discussed.  (+info)

Bartonella henselae is a zoonotic agent in which the domestic cat serves as the natural reservoir, and humans acquire potentially serious infections associated with this microorganism. The purpose of this research is to contribute to the understanding of the pathogenesis of B. henselae in the domestic cat using a molecular approach. Using sequence differences in a portion of the I 6S rRNA gene between B. henselae genotype I, and B. henselae genotype II, a nested polymerase chain reaction (nPCR) was designed and used to investigate various phases of feline bartonellosis. The nPCR detected 3.2 organisms per milliliter of blood which is below the detection limits of standard bacterial culture. Bartonella henselae LSU 16 genotype II, Bartonella henselae Baby genotype II, Bartonella henselae 87--66 genotype I, and Bartonella henselae Houston-1 genotype I were used in this study to infect cats. The PCR assay detected Bartonella DNA in 40 blood samples that were culture negative. The bacteremia as
Commonly abbreviated as CSD, Cat Scratch Disease is an infectious disease caused by the bacteria Bartonella henselae. As the name suggests, CSD is often caused by scratches and bites from cats that become infected. An indication of CSD is when the lymph nodes around the neck, heads, and sometimes the upper limbs show signs of swelling. Other symptoms of CSD may include fatigue, fever, headache, and a loss of appetite. In rare instances, complications from CSD may arise such as Parinauds oculolandular syndrome and bacillary angiomatosis. Cats do have the capacity to spread Bartonella henselae to humans. Kittens pose a greater risk than cats and pass the bacterium onto their owners more often than adult cats. At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. Cats who are carriers display no symptoms and will not act sickly. It is impossible to tell whether or not a cat can spread the disease to their owner.. Individuals with weak ...
It is reported that up to 95% of patients with Cat Scratch Disease present antibodies against Bartonella henselae antigens. Through a type IV secretory system, B. henselae proteins are transported into the host cells. The encoding gene of outer membrane protein p26 has significant nucleotide identity with orthologs in Brucella spp., Bartonella spp., and several plant-associated bacteria ...
B. henselae infection initiates after trauma to the skin, suggesting that adherence to host cells may be mediated by specific interactions between B. henselae surface proteins such as Pap31 and components of the host ECM such as Fn and Hep. Pap31 was previously shown to be involved in acquisition of heme and thus may be an important virulence factor for B. henselae (8, 53). Because heme receptor molecules are surface exposed, we undertook to determine if Pap31 had another virulence function as an adhesin to ECM. We have expressed and purified B. henselae Pap31 with high yield and purity and demonstrated its immunogenicity. We also demonstrated that Pap31 acts as a potential ligand for Fn and Hep, indicating its broad-range binding ability. Recognition of anti-Pap31 antibodies in rabbits or mice vaccinated with live B. henselae or purified Pap31, respectively, indicated that the protein is expressed in vivo and contributes to the humoral immune response in the host defense against B. henselae. ...
Infection of humans with the zoonotic bacterium Bartonella henselae (Bh) can result in a range of clinical symptoms and disease including lymphadenopathy associ...
Gentaur molecular products has all kinds of products like :search , Fuller \ Bartonella henselae 12_well Substrate Slide Species Human_Canine_Equine \ BH-12 for more molecular products just contact us
The potential role of ticks as vectors of Bartonella species has recently been suggested. In this study, we investigated the presence of Bartonella species in 271 ticks removed from humans in Belluno Province, Italy. By using primers derived from the ...
One of the most striking examples of how Lyme disease co-infections can wreak havoc on the extracellular matrix and connective tissues comes from a 2018 study that looked at the effects of Bartonella infection, rheumatological symptoms and associated joint hypermobility (8). The case study publication concerned a female veterinarian who displayed the clinical symptoms of EDS (Ehlers-Danlos Syndrome), Type 3. Type 3 EDS is considered to be the most severe form of EDS, chiefly affecting the vascular system, and leading to a significantly reduced life expectancy. The patient was identified as having a Beighton hypermobility score of 7/9.. The patient was found to have Bartonella koehlerae and Bartonella henselae infections. Bartonella bacterial infections have a notable and destructive effect on the vasculature and endothelial functions. The patient was treated for bartonella using the longterm use of antibiotics. The treatment resulted in the resolution of the patients symptoms, and notably the ...
Cat scratch disease, a mild flu-like infection, with swollen lymph nodes (lymphadenitis) and mild fever of short duration, due to cat scratches, especially from kittens. There is usually a little bump (a papule) which may be pus-filled (a pustule) at the site of the scratch. The infection is self-limited and usually goes away by itself in a few weeks. It can also be treated with antibiotics, but it can cause a severe inflammation called bacillary angiomatosis in patients with weakened immune systems. A cat carrying the microbe does not show symptoms and it is not necessary to get rid of it. If someone in the household is at high risk, a test to detect the infection can be done and the cat can be treated. The disease is caused by a bacterium called Rochalimaea henselae, eventually reclassified as Bartonella henselae, named for Diane Hensel, a microbiologist. The disease has also been called regional lymphadenitis. ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Principal Investigator:MARUYAMA Soichi, Project Period (FY):1998 - 1999, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Applied veterinary science
Enseleit, F; Wyss, C A; van der Loo, B; Grünenfelder, J; Oechslin, E N; Jenni, R (2009). Isolated cleft in the posterior mitral valve leaflet: a congenital form of mitral regurgitation. Clinical Cardiology, 32(10):553-560.. Kovacevic-Preradovic, T; Jenni, R; Oechslin, E N; Noll, G; Seifert, Burkhardt; Attenhofer Jost, C H (2009). Isolated left ventricular noncompaction as a cause for heart failure and heart transplantation: a single center experience. Cardiology, 112(2):158-164.. Luthi, P; Zuber, M; Ritter, M; Oechslin, E N; Jenni, R; Seifert, B; Baldesberger, S; Attenhofer Jost, C H (2008). Echocardiographic findings in former professional cyclists after long-term deconditioning of more than 30 years. European Journal of Echocardigraphy, 9(2):261-267.. Fischer, A H; van der Loo, B; Shär, G M; Zbinden, R; Duru, F; Brunckhorst, C; Rousson, V; Delacrétazy, E; Stuber, T; Oechslin, E N; Follath, F; Jenni, R (2008). Serological evidence for the association of Bartonella henselae infection with ...
Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) has been cited in 4 publications. Find out more about the references
Abcam provides specific protocols for Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) : Immunohistochemistry protocols
This disease is caused by an infection with the organism Bartonella henselae that occurs following being scratched by a cat. Includes its epidemiology, presentation, differential diagnosis, investigation and management. ...
Worldwide distribution. Transmission from cat to human mainly occurs by cat scratch or bite, possibly by flea bite.. Domestic cats are the main reservoir of Bartonella henselae. Epidemiological studies showed bacteria prevalence ranging from 15% to 55% in many countries, including Europe, United States, Asia, Australia and Africa.. No direct transmission from cat to cat in a flea-free environment and no vertical transmission from infected queens to their kittens have been observed. ...
The genus Bartonella contains Gram-negative arthropod-borne bacteria that are found in many small animal reservoirs and are capable of causing human disease. Bacteria utilize a general stress response system to combat stresses from their surrounding environments. In α-proteobacteria, the general stress response system uses an alternate σ factor as the main regulator and incorporates it with a two-component system into a unique system. Our study identifies the general stress response system in the α-proteobacterium, Bartonella henselae, where the gene synteny is conserved and both the PhyR and alternate σ factor have similar sequence and domain structures with other α-proteobacteria. Furthermore, we showed that the general stress response genes are up-regulated under conditions that mimic the cat flea vector. We also showed that both RpoE and PhyR positively regulate this system and that RpoE also affects transcription of genes encoding heme-binding proteins and the BadA adhesin. Finally, we also
Buy viagra online canadian - It is more common in immunocompromised bite victims bartonella henselae is the viagra buy online canadian sympathetic pathway to segments t l gupta r k a the metanephric kidney curr top dev biol a kume t deng k and sandford r cardiovascular skeletal and dental injuries the. All tablets dosages available today. Read on to learn more about our online pharmacy, how to get started, and the many advantages of purchasing Viagra online from …. 100% Satisfaction Guaranteed! These physical symptoms are smiley faces all caps Generic Viagra Online comes into strength of 100mg. Free shipping, quality, privacy, secure. Lowest Prices. Tension whether of muscle Blood Donation Cialis buy viagra online canada tension indispensable latterly 4 component an. Health Care specializes in registered nurses, physicians, doctors, hospital management jobs as well as other employment in healthcare. 26 urinary retention definition10 the state in which one lives as how the desired groups or ...
1. the most important clues for Dx. ① Hx. of contact with animals. (esp. kittens). ② identification of an inoculation skin or ocular lesion. 2. regional lymphadenopathy. (cat contact후 몇주후에 발생됨). : CSD suggest. → 특히 primary inoculation papule혹은 pustule이 cat scratch후 생겼다면. 3. criteria for a definitive diagnosis. ① contact with a cat & the presence of a scratch or primary lesion of the dermis, eye, or a mucous membrane. ② a positive skin test for CSD or. positive serologic test for B. henselae antibody. ③ negative serologies,. including purified protein derivative skin tests & culures of aspirated pus or LN performed for other causes of lymphadenopathy. ④ characteristic pathologic features in biopsy specimen of skin, LN or ocular granuloma. : clinical practice. → Dx은 4가지 criteria중 3가지 (+)인 경우 4. confirm in atypical cases. : fourfold rise in titer for B. henselae or by demonstrating small, pleomorphic bacilli. in Warthin-Starry ...
...HOUSTON-(May 23 2011)-People with diabetes have a three to five times...Results of the study which included 233 patients with TB who live in ... With the increase in diabetes patients in TB-endemic areas our findi...Study results found 25 percent of TB cases were attributed to the pres...,UTHealth,researchers,find,diabetics,at,higher,risk,of,tuberculosis,infection,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Śródbłonkowe działanie aldosteronu implikacje terapeutyczne płynące z badań podstawowych i klinicznych Endothelial action of aldosteron therapeutic implications from basic and clinical research. Drelicharz
Centrum Badań DNA to nowoczesny medyczny ośrodek naukowo-diagnostyczny, oferuje badania genetyczne i diagnostykę zakażeń w oparciu o najnowsze technologie diagnostyczne
Centrum Badań DNA to nowoczesny medyczny ośrodek naukowo-diagnostyczny, oferuje badania genetyczne i diagnostykę zakażeń w oparciu o najnowsze technologie diagnostyczne
Ilikuwa ni sherishori pale mchungaji wa kanisa la calvari la urafiki ambae aliamua kumtambulisha kifaa chake kipya baada ya kufiwa na mkewe miezi...
Suplement do dyplomu Doświadczenia Wyższej Szkoły Humanistyczno-Ekonomicznej w Łodzi Renata Figlewicz Centrum Badań i Rozwoju Kształcenia Wyższa Szkoła Humanistyczno-Ekonomiczna w liczbach 2 wydziały 10
Autorskie projekty badawcze z zakresu neurologii, ortopedii, toksykologii, chirurgia doświadczalnej, onkologii, badań metabolicznych i behawioralnych (AnyMAZE, basen Morrisa, klatki strachu, Intellicage ...
Cat scratch disease is also known as cat scratch fever. This disease strikes people who are infected by the Bartonella henselae bacteria. In almost all cases, cat scratch disease occurs when the person was scratched or bitten by his cat. The cat itself does not catch cat scratch disease. It is just a carrier. Now, before you panic and send your cat to the pound, the National Center for Infectious Diseases (CDC) estimates that 40% of all cats carry this disease at some time in their lives. Considering how many cat owners exist in the world, clearly, this disease is not very infectious or dangerous.. But how do you know whether you were infected by cat scratch disease? The first thing you want to look at is the place your cat bit or scratched you. Is the wound infected? (Note: If you cannot find the wound, then you do not have cat scratch disease.) Then you want to check your lymph nodes. Are the nodes around your head, neck and upper limbs swollen? Do you also have fever, headache, fatigue, and a ...
IIIChris Hani Baragwanth Hospital, Bertsham, South Africa. Correspondence to. Bartonella is a genus of opportunistic, Gram-negative bacilli transmitted from animals to human hosts. Bartonellae are newly emerging pathogens that can cause a variety of clinical manifestations in both immunocompromised and healthy persons.. The aims were to determine the IgG and IgM seroprevalences of Bartonella henselae and Bartonella quintana in immunocompromised and immunocompetent individuals using an immunofluorescence assay (IFA).. A total of 382 HIV-positive outpatients of the Chris Hani Baragwanth HIV-clinic, 382 retrospective residual samples from HIV-negative antenatal patients, and 42 clinically healthy volunteers were tested using a commercially available IFA kit to determine the prevalence of IgG and IgM antibodies to B. henselae and B. quintana.. The IgM and IgG seroprevalences for the HIV-positive patients were 14% (53/382) and 32% (121/382), respectively, compared to 18% for both IgM (62/342) and IgG ...
IIIChris Hani Baragwanth Hospital, Bertsham, South Africa. Correspondence to. Bartonella is a genus of opportunistic, Gram-negative bacilli transmitted from animals to human hosts. Bartonellae are newly emerging pathogens that can cause a variety of clinical manifestations in both immunocompromised and healthy persons.. The aims were to determine the IgG and IgM seroprevalences of Bartonella henselae and Bartonella quintana in immunocompromised and immunocompetent individuals using an immunofluorescence assay (IFA).. A total of 382 HIV-positive outpatients of the Chris Hani Baragwanth HIV-clinic, 382 retrospective residual samples from HIV-negative antenatal patients, and 42 clinically healthy volunteers were tested using a commercially available IFA kit to determine the prevalence of IgG and IgM antibodies to B. henselae and B. quintana.. The IgM and IgG seroprevalences for the HIV-positive patients were 14% (53/382) and 32% (121/382), respectively, compared to 18% for both IgM (62/342) and IgG ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin. Rubbing the eyes after petting a cats fur can also spread cat scratch disease. Young kittens younger than 1 year of age are more likely to scratch, increasing the likelihood of infection.. ...
Cat scratch disease (CSD), due to Bartonella henselae, is a self-limited chronic lymphadenopathy. A previously healthy 22-year-old woman presented with a palpable painful swelling in the right submandibular region accompanied by enlarged cervical lymph nodes. A diagnosis of B. henselae infection was made according to her personal history that divulged frequent contacts with cats and to a high titre of immunoglobulin G (IgG) and IgM antibodies for this agent. The patient improved within 1 month without the requirement of antibiotic treatment or surgery. The CSD should always be included in the differential diagnosis of all equivocal masses in the neck, especially in young individuals. In addition, it is important that a meticulous personal history is obtained. ...
The diagnostic value of the detection of immunoglobulin G (IgG) and IgM by Bartonella henselae-based indirect fluorescence assay (IFA) and enzyme-linked immunoassay (EIA) for the diagnosis of cat scratch disease (CSD) was evaluated. The IFA was performed either with B. henselae that was cocultivated for a few hours with Vero cells or with noncocultivated B. henselae as the antigen. Additionally, the performance of a Bartonella PCR hybridization assay based on the 16S rRNA gene was determined and compared with those of the serologic assays. The study group consisted of 45 patients suspected of suffering from CSD by fulfilling one or more of the classical criteria. The specificities of the immunoassays were set at , or = 95% by analysis of sera from 60 healthy blood donors. It is shown that the sensitivities of the IgG assays are very low (40.9% for the IFA with noncocultivated B. henselae as antigen) and that those of the IgM assays are higher (71.4% for the EIA) for patients who fulfilled two or ...
Cat scratch disease, commonly called cat scratch fever, is an infection caused by Bartonella henselae, a bacterium carried in the saliva of infected cats. According to the KidsHealth website, ...
The currently accepted model explaining the infection cycle holds that the transmitting vectors are blood-sucking arthropods and the reservoir hosts are mammals. Immediately after infection, the bacteria colonize a primary niche, the endothelial cells. Every five days, some of the Bartonella bacteria in the endothelial cells are released into the blood stream, where they infect erythrocytes. The bacteria then invade a phagosomal membrane inside the erythrocytes, where they multiply until they reach a critical population density. At this point, they simply wait until they are taken up with the erythrocytes by a blood-sucking arthropod. Though some studies have found "no definitive evidence of transmission by a tick to a vertebrate host," [7][8] Bartonella species are well-known to be transmissible to both animals and humans through various other vectors, such as fleas, lice, and sand flies.[9] Recent studies have shown a strong correlation between tick exposure and bartonellosis,[9][10] including ...
Kittens can be diagnosed as cat scratch disease carriers through a simple blood test, and positive kittens can be treated successfully with antibiotics. Because this disease can come back, however, this is not a silver bullet for preventing cat scratch disease. Declawing kittens at an early age is the best way to prevent infection. You should be aware of the ramifications to the cat before declawing it, however. Not only can it be dangerous for the cat to go outside, it can also be psychologically traumatic and cause unexpected complications like arthritis ...
Case Reports in Pediatrics is a peer-reviewed, Open Access journal that publishes case reports related to pediatric subspecialities, such as adolescent medicine, cardiology, critical care, dentistry, developmental and behavioral medicine, endocrinology, gastroenterology, genetics, haematology and oncology, neo- and perinatology, nephrology, neurology, psychology, pulmonology, rheumatology, and surgery.
Cat-scratch disease, also called bartonellosis, is by far the most common zoonotic disease associated with cats. Cat-scratch disease can occur when a person is bitten or scratched by an infected cat. Fleas may also play a role in the transmission of infection. People with cat-scratch disease usually have swollen lymph nodes, especially around the head, neck, and upper limbs. They may also experience fever, headache, sore muscles and joints, fatigue, and poor appetite. Some healthy cats are continuously or intermittently infected with cat-scratch disease bacteria. Avoiding scratches and bites, controlling fleas, and keeping cats indoors all reduce the risk of cat-scratch disease.. Fleas are the most common external parasite of cats. While fleas cannot thrive on humans, their bites can cause itching and inflammation. Fleas may also serve as vectors for cat-scratch and other zoonotic diseases. Flea-infested cats may become infected with tapeworms from fleas ingested while grooming. Children can ...
Cat scratch fever is a cat scratch disease that is is caused by bacteria called Bartonella henselea with symptoms that include high fever, anorexia, weakness, and badly swollen lymph nodes.
English , R. " Cat-scratch disease". Pediatr Rev . vol. 27. 2006. pp. 123-8. (An in-depth review of the clinical features of CSD, including a nice discussion of the etiology and epidemiology of the disease. Also highlights the features of atypical disease in immunocompetent and immunocompromised hosts.) Reynolds , MG, Holman , RC, Curns , AT, OReilly , M, McQuiston , JH, Steiner , CA. " Epidemiology of cat-scratch disease hospitalizations among children in the United States". Pediatr Infect Dis J . vol. 24. 2005. pp. 700-4. (This analysis of a national inpatient database examined the CSD-associated hospitalization rate among children for a specific year. The authors found that despite the increasing incidence of cat ownership from previous years, the overall hospitalization rate for CSD did not increase. They also found that early diagnosis by serologic testing obviated the need for unnecessary intervention.) Bass , JW, Cary Freitas , BC, Freitas , AD. "Prospective randomized double blind ...
I dont have any scratches that are not healed or I havent had any that were infected at all. I always clean a scratch even a minor scratch as soon as it happens but previously working as a nurse noticed these symptoms as cat scratch disease although I dont have an infected scratch! Anyways with my lymphnodes being swollen not only under my arm but on my back and the inside of my upper leg I know I have some kind of infection! I am getting an antibiotic shot this afternoon and RX for antibiotics and taking BB to have her tested I was informed by the vet that if she test positive for it they can give her antibiotics to kill the bacteria even though she just had three antibiotic shots for her operation! This is crazy I never knew a cat scratch could be so dangerous . I am so sorry to all of you who have lost loved ones to this it just seems like such a minor problem and maybe that is why people dont think of it as urgent of life threatning! Thanks for all of your responses ...
Lymphoreticulosis Symptoms. EVERYTHING, THAT YOU WANTED TO KNOW ABOUT CATSCRATCH DISEASE (lymphoreticulosis), lymphoreticulosis SYMPTOMS. EFFECTIVE TREATMENT OF CAT-SCRATCH DISEASE. http://www.biofon.ru/eng/treat/catalog/lim.shtml Extractions: Cat-scratch disease (benign lymphoreticulosis) Â- infectious disease associated with a history of scratches, bites from or close contact with a cat. The infecting agent is Bartonella henselae a tiny bacillus of familia Chlamydiae. The host and the source of infection are cats, with the infection agent being a normal part of their mouth flora. Person-to-person transmission of the disease has not been shown. The infection enters through skin wounds causing inflammation. Carried by lymph the infection reaches the nearest lymph node causing its inflammation too. Further the infection spreads with the bloodstream over the system. After convalescence the body develops persistent immunity to the disease. Treating cat-scratch disease (lymphoreticulosis). Symptoms ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. Research suggests a cat may get these bacteria from fleas. The bacteria are passed from an infected cat to a human after the cat licks an open wound or bites or scratches human skin hard enough to break the surface of the skin. Kittens younger than one year of age are more likely to scratch, increasing the likelihood of infection. ...
Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin.
Cat-scratch disease is an infection you can get after a cat scratches, bites, or licks you. Its caused by bacteria in cat saliva. Its usually not severe.
Cat-scratch disease is seasonal in the United States and Japan; but no data are available from Europe. To assess the seasonality of the disease in France, we analyzed lymph node biopsy specimens collected during 1999-2009. Most (87.5%) cases occurred during September-April and peaked in December.
Addresses: Andersson SGE, Uppsala Univ, Evolutionary Biol Ctr, Dept Mol Evolut, S-75236 Uppsala, Sweden. Uppsala Univ, Evolutionary Biol Ctr, Dept Mol Evolut, S-75236 Uppsala, Sweden. Univ Basel, Bioctr, Dept Mol Microbiol, CH-4056 Basel, Switzerland.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14 ...
These Pathogen Safety Data Sheets, regulated under Workplace Hazardous Materials Information System (WHMIS) legislation, are produced for personnel working in the life sciences as quick safety reference material relating to infectious micro-organisms.
Bartonella species can be isolated (with difficulty) from blood, using ethylenediaminetetraacetic acid (EDTA) tubes. The organisms have been isolated from tissue in only a few laboratories because of the fastidious nature of Bartonella.2 Polymerase chain reaction methods have been developed for identification and speciation of Bartonella but are not widely available.. Preventing Exposure. HIV-infected patients, specifically those who are severely immunocompromised (CD4 counts ,100 cells/mm3), are at high risk of severe disease when infected by B. quintana and B. henselae. The major risk factors for acquisition of B. henselae are contact with cats infested with fleas and receiving cat scratches. Immunocompromised individuals should consider the potential risks of cat ownership (AIII). Patients who want cats should acquire animals that are older than age 1 year and in good health (BII). Cats should be acquired from a known environment, have a documented health history, and be free of fleas. Stray ...
Cat scratch fever: Find the most comprehensive real-world symptom and treatment data on cat scratch fever at PatientsLikeMe. 15 patients with cat scratch fever experience fatigue, depressed mood, pain, anxious mood, and insomnia and use Amphetamine-Dextroamphetamine, Heating Pad-Hot Packs, Ibuprofen, and Massage Therapy to treat their cat scratch fever and its symptoms.
Bartonella species are members of the alpha-2 subgroup of the class Alphaproteobacteria, within the Rhizobiales order. There are now more than 22 species or subspecies described, and DNA sequences from numerous other species or strains have been deposited in GenBank. Warthin-Starry silver stain is recommended for microscopic detection of Bartonella organisms in fixed tissue sections but is not highly specific and is insensitive, even with lymph node biopsy samples from cat scratch disease (CSD) patients. In contrast, even when isolation of the infecting species is not possible, PCR amplification of internal transcribed spacer (ITS) DNA directly from diagnostic samples and/or from enrichment cultures followed by nucleic acid sequencing is an invaluable tool for primary identification at the species, subspecies, and genotype levels. The first serologic test for CSD was an immunofluorescence antibody assay (IFA) based on B. henselae bacilli that were cocultivated with Vero cells to inhibit
Cat-scratch disease (CSD) is a common and usually harmless infectious disease induced by the bacterium Bartonella henselae. It really is most commonly within children carrying out a scuff or bite from a feline within about one or two weeks.. see more at wikipedia. ...
DIAGNOSIS. Blood culture or fluid aspirated from the joints has the characteristic causative organism.. Animal inoculation: Spirillium minus can be demonstrated.. Blood picture - the disease is accompanied by leucocytosis and sometimes eosinophilia.. TREATMENT. Penicillin is an effective antibiotic for treatment of rat bite fever.. Cauterization of the wound by nitric acid may prevent spread of the disease when this is applied early after the bite.. CAT SCRATCH DISEASE. Cat scratch disease is caused by Gram-negative rods, which are part of the normal bacterial flora of cats, dogs and some other animals.. Most of the patients are children playing with cats, dogs that are a vector for the organism. Infection reaches the skin through traumatization of the skin by the cat scratch or by cat biting.. General manifestations. Fever, malaise and anorexia are not uncommon following the cat scratch. Central nervous system involvement. Purpura, thrombocytopenia and eye involvement are rare complications of ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrións disease, caused by B. bacilliformis.
As pet owners we seldom think about how our cat or dogs illness might negatively impact us beyond that of the regular inconvenience of visits to the vets, medical bills, and the cost of prescription drugs, etc. Most illnesses and common ailments that assail pets are non-transferable to humans, leaving us little reason to be concerned for our own welfare. However, though many people are not aware of it, there do exist certain diseases and bacteria which can be passed from a dog or cat to their human owner. Here are some of the illnesses to watch out for.. Cat Scratch Disease: Though the name of the disease sounds nonthreatening and trivial, it is an unpleasant experience to suffer from Cat Scratch Disease. Bacteria can be passed from the cats saliva (if he bites someone) or through this claws (by scratching). The victim would then suffer from fevers, headaches, lethargy, and swollen lymph nodes anywhere from a week to two weeks after the incident. The good news is, only about 40% of cats carry ...
What are the symptoms?. This is not a particularly serious or dangerous disease. It shows up in the form of enlargement of the lymph nodes. Lymph nodes are little glands that are a part of your immune system, and they are located in your armpit, groin, neck, and chest. When you get it, they work overtime and can start to swell. This lasts for about a month or so, and they may drain pus. Other symptoms include fevers, lethargy, headaches, and loss of appetite. What is the treatment?. Usually your doctor will just tell you to wait it out. The immune system will heal it on its own within three to six weeks in the vast majority of cases. If the person shows more severe symptoms, the doctor may want to use antibiotics to speed it up. There isnt a cure that will instantly make it go away.. Do I need to get rid of my cat if I get sick?. No. First of all, even most people who get scratched dont get it. Second, this is not a disease that you get multiple times. No one has ever been seen catching it ...
Psychiatry healthcare professionals gain a thorough knowledge base of psychiatric disorder information to offer the best patient care. Get our FREE app now.
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common medical conditions in daily practice.
How to Deal With a Cat Scratch. Cats can be playful, quirky, or occasionally aggressive. If you spend time around cats, its quite possible that you will suffer from a cat scratch at some point. Cats have sharp claws that they use to...
Cats can be cute - but they bring home more than mice. Scratches and bites can cause infections, from cat-scratch disease to MRSA bacteria to rabies.
Enlarged Spleen In Dogs found in: Dog Hemangiosarcoma, Ehrlichia Infection, Dog Malignant Histiocytoma, Dog Oral Squamous Cell Carcinoma, Cat Bartonella and Cat Scratch Disease, …does however, serve an important role..
... ,ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories client,medicine,medical supply,medical supplies,medical product
Pantera Cat Scratch Fever lyrics & video : Im high! Well, I dont know where they come from, but they sure do come I hope theyre comin for me And I dont know how they do it,...
The cat scratch disease (CSD) skin test was once used to help diagnose CSD. The test is no longer used today. There are better methods available to diagnose CSD, such as antibody detection by the EIA test or bacteria detection by a PCR (polymerase chain reaction) test.
Her doctors couldnt figure out what was wrong. After some prodding, they told her father that Alexus had cat-scratch disease. Amadeo Rodriguez pushed back on that diagnosis - the family didnt have cats, and there had been no time in the preceding weeks when Alexus could have been scratched by one.. He was skeptical, but he let it go.. The following Monday, he arrived at work and promptly told his supervisor, You know what? Im gonna go. Somethings wrong, and I just have a gut feeling that somethings wrong.". That day, Armadeo Rodriguez pushed doctors for a biopsy. Then, on Wednesday, July 11, 2012, he got the phone call. Alexus had stage four Burkitts lymphoma.. "I already knew it," he said. "I had a hunch. I had a hunch that it was cancer. … All the signs were there, because I was doing research. And everything that I researched pointed to cancer.". Alexus immediately started chemotherapy. The cancer was in her lymph nodes, her liver and her bone marrow. In total, she had 12 bone ...
Buy Zitrocin Online! Zitrocin is an antibiotic used to treat a variety of bacterial infections, such as cat-scratch disease, ear infections, infections of the skin or surrounding tissue, and throat or tonsil infections. Doctors may also prescribe Zitrocin for genital infections and sexually transmitted diseases, such as gonorrhea, infections of the urethra or cervix, genital ulcers, and severe pelvic inflammatory disease.
Even seemingly healthy pets can carry parasites, bacteria, or viruses that cause mild to life-threatening illness in their owners.. Of the 250 diseases that can be passed between animals and people, more than 100 can come from household pets, says researcher Bruno Chomel, D.V.M., Ph.D., at the University of California School of Veterinary Medicine.. Dr. Chomels research was published in the February issue of the journal Emerging Infectious Diseases. He cited a 69-year-old man whose dog slept under the covers with him and licked his hip replacement wound. The man came down with meningitis. In another incident, a 9-year-old boy picked up plague, a potentially deadly bacterial infection, from sleeping with his flea-infested cat.. But zoonotic diseases can also be passed to people who kiss their pets or are licked by them. In addition to meningitis and plague, other animal-people infections include hookworm, roundworm, and cat scratch disease.. ...
I recently received a comment in my Scratch Messages box from VauHaEs, a Scratcher in Germany. He liked and complimented one of my shared projects (online at the Scratch web site) so I clicked on his name to view his profile. There, I was able to view all of the projects he had uploaded to the Scratch web site and I was immediately intrigued by his line-robot project ...
Breast Fav-store specialize in supplying special featured herbal medecines, developed to improve your life and makes better your health. We present a 60 day full money back guarantee. Breast ko bada krne ke liye capsul.
Lil B Im The Bada$$ lyrics & video : [Intro] These niggas think they badasses now, huh? This your boy Lil B - Pink Flame [Verse 1] Cant f**k with me these niggas know ...
Generally, it takes only a few days for scratches to heal. However, it may take several weeks or months for scratches to completely heal. The healing rate depends on a number of factors, such as the...
Although no lens material is scratch-proof, its important to protect your lenses with a scratch resistant treatment. Ask about scratch protection today!
... : Scratch brushes are ideal for fine deburring, polishing, and rust removal. Brushes
| Final photos here | I hope you enjoy :) [IMG] After several deskbuilds, lots of UV green and upgrade of my own desk its time for something...
Obsidian Portal allows you to create campaign websites for tabletop roleplaying games. Better manage your group and your campaign, and have a better game.
We report detection of Bartonella henselae DNA in blood samples from 2 harbor porpoises (Phocoena phocoena). By using real-time polymerase chain reaction, we directly amplified Bartonella species DNA from blood of a harbor porpoise stranded along the northern North Carolina coast and from a preenrichment blood culture from a second harbor porpoise. The second porpoise was captured out of habitat (in a low-salinity canal along the northern North Carolina coast) and relocated back into the ocean. Subsequently, DNA was amplified by conventional polymerase chain reaction for DNA sequencing. The 16S-23S intergenic transcribed spacer region obtained from each porpoise was 99.8% similar to that of B. henselae strain San Antonio 2 (SA2), whereas both heme-binding phage-associated pap31 gene sequences were 100% homologous to that of B. henselae SA2. Currently, the geographic distribution, mode of transmission, reservoir potential, and pathogenicity of bloodborne Bartonella species in porpoises have not been
Bartonella spp. are responsible for emerging and re-emerging diseases around the world. The majority of human infections are caused by Bartonella henselae, Bartonella quintana and Bartonella bacilliformis, although other Bartonella spp. have also been associated with clinical manifestations in humans. The severity of Bartonella infection correlates with the patients immune status. Clinical manifestations can range from benign and self-limited to severe and life-threatening disease. Clinical conditions associated with Bartonella spp. include local lymphadenopathy, bacteraemia, endocarditis, and tissue colonisation resulting in bacillary angiomatosis and peliosis hepatis. Without treatment, Bartonella infection can cause high mortality. To date, no single treatment is effective for all Bartonella-associated diseases. In the absence of systematic reviews, treatment decisions for Bartonella infections are based on case reports that test a limited number of patients. Antibiotics do not significantly ...
Bartonella vinsonii is a gram-negative bacteria from the genus of Bartonella which was isolated from dogs Rochalimaea vinsonii was reclassified to Bartonella vinsonii Bartonella vinsonii contains the two subspecies Bartonella vinsonii subsp. vinsonii and Bartonella vinsonii subsp. berkhofli. Bartonella vinsonii subsp. vinsonii has been isolated from voles and Bartonella vinsonii subsp. berkhofli was isolated from a dog with endocarditis. Bartonella vinsonii subsp. berkhoffii can cause diseases in humans. Those two subspecies are named after J. William Vinson and Herman A. Berkhoff. LPSN bacterio.net Straininfo of Bartonella vinsonii uniProt Bartonella vinsonii subsp. berkhofii subsp. nov., Isolated fromDogs; Bartonella vinsonii subsp. vinsonii; and EmendedDescription of Bartonella-vinsonii Cadenas, M. B.; Bradley, J.; Maggi, R. G.; Takara, M.; Hegarty, B. C.; Breitschwerdt, E. B. (2008). "Molecular Characterization of Bartonella vinsonii subsp. Berkhoffii Genotype III". Journal of Clinical ...
Bartonella infection: Find the most comprehensive real-world symptom and treatment data on Bartonella infection at PatientsLikeMe. 60 patients with Bartonella infection experience fatigue, depressed mood, pain, anxious mood, and insomnia and use Azithromycin, Doxycycline, Rifampin, L-Carnitine, and Minocycline to treat their Bartonella infection and its symptoms.
Cat scratch disease is a bacterial infection carried in cat saliva. It is passed from a cat bite or scratch to a human. It can also result from a fleabite, but cats are the main source.
Bacillary Angiomatosis: A reactive vascular proliferation that is characterized by the multiple tumor-like lesions in skin, bone, brain, and other organs. Bacillary angiomatosis is caused by infection with gram-negative Bartonella bacilli (such as BARTONELLA HENSELAE), and is often seen in AIDS patients and other IMMUNOCOMPROMISED HOSTS.
What is Bartonella? When one forays into the world of chronic Lyme disease the word Bartonella immediately comes up. What is it? I have written about it from time to time and treated it for a long time. What do we know? Medical textbooks and published papers are at odds with "Lyme" literature. Bartonella is classified as a new and emerging infectious disease. Clinical infection is largely seen as opportunistic. This means that Bartonella under normal circumstances is unlikely to cause clinical disease: it has low pathogenicity. Commercial laboratories only offer serological tests for two species, B. henselae and B. quintana. Newer information informs us that numerous other species, including: B. koehlerae, B. vinsonii and B. berkhoffi have been found in the blood of Lyme patients. Doctors have known about the prevalence of Bartonella species in some populations for some time. A study published in 1996 looked at the incidence of three species of Bartonella found in inner-city IV drug users in ...
What is Bartonella? When one forays into the world of chronic Lyme disease the word Bartonella immediately comes up. What is it? I have written about it from time to time and treated it for a long time. What do we know? Medical textbooks and published papers are at odds with "Lyme" literature. Bartonella is classified as a new and emerging infectious disease. Clinical infection is largely seen as opportunistic. This means that Bartonella under normal circumstances is unlikely to cause clinical disease: it has low pathogenicity. Commercial laboratories only offer serological tests for two species, B. henselae and B. quintana. Newer information informs us that numerous other species, including: B. koehlerae, B. vinsonii and B. berkhoffi have been found in the blood of Lyme patients. Doctors have known about the prevalence of Bartonella species in some populations for some time. A study published in 1996 looked at the incidence of three species of Bartonella found in inner-city IV drug users in ...
https://insights.ovid.com/crossref?an=00055735-201711000-00011 Current Opinion in Ophthalmology. 28(6):607-612, NOV 2017 DOI: 10.1097/ICU.0000000000000419 Ophthalmic manifestations of bartonella infection Radgonde Amer; Ilknur Tugal-Tutkun Abstract Purpose of review The eye is commonly affected in disseminated cat scratch disease (CSD) caused by Bartonella species. This article reviews recently published data on epidemiology of CSD, clinical features of ocular involvement, diagnosis and…
Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. Incidental infection of other hosts is however often followed by various disease symptoms, and several Bartonella species are considered as emerging human pathogens.. In this work, I have studied the genomic diversity within and between different Bartonella species, with focus on the feline-associated human pathogen B. henselae and its close relatives, the similarly feline-associated B. koehlerae and the trench-fever agent B. quintana which is restricted to humans.. In B. henselae, the overall variability in sequence and genome content was modest and well correlated, suggesting low levels of intra-species recombination in the core genome. The variably present genes were located in the prophage ...
Cancer Therapy Advisor provides dermatologists with the latest dermatology conditions, procedures and guides for different surgical and non surgical conditions. Visit often for updates and new information.
IgM antibody, the primary immune response to Bartonella, appears early in the infection and is highly diagnostic when present. IgG antibody response follows initial IgM response closely. Since the IgG response is broadly cross reactive between the species, these results must be interpreted with caution. 10% of a healthy population exhibit Bartonella henselae and B. quintana IgG titers of 1:64 - 1:128; none show titers of 1:256 or above ...
Toxoplasmosis is a single-celled parasite. Infected cats secrete oocysts that contaminate cat litter. A person who inadvertently gets the cysts on her hands, touches her mouth and swallows can be infected. Other ways to catch toxoplasmosis are eating contaminated food or undercooked meat. Most people never develop symptoms, or develop a flu-like illness with muscle aches and swollen glands lasting up to a month. A few people, often but not always patients who are immunocompromised, can develop infections of the brain or eyes. The unborn can be infected though the placenta by an infected mother. These fetuses may die, or develop permanent damage to the brain, or eyes.. Cat-scratch disease is caused by the bacteria Bartonella henselae. This bacterium is spread by cat claws contaminated with flea feces. Symptoms include fever and enlarged lymph nodes days to weeks after a cat scratch.. Dogs, my personal favorite pet, can spread infections too. Ringworm, a fungal infection, can be spread by direct ...
Director, Louisiana Veterinary Medical Diagnostic Laboratory, Department of Agriculture, Baton Rouge, Louisiana. Veterinarians often are consulted by the public, and occasionally by physicians and other veterinarians, for information regarding zoonoses (diseases that are transmitted to humans from animals). When a person is diagnosed with an illness that is somewhat out of the ordinary, many times relatives are worried that the family pet was the source of the trouble. Usually, however, the diseases in question are not zoonoses. There are physicians who, perhaps seeking zero risk, advise patients to dispose of pets to prevent or alleviate a zoonotic illness. Pregnant women have been advised to get rid of their cats to prevent their contracting toxoplasmosis; HIV-positive people may be told they that should not have animals at all. Although this advice may be well intended, it is often ill informed. Too often, what is missing is some reasonable approximation of the true risk of disease ...
Case Reports in Oncological Medicine is a peer-reviewed, Open Access journal that publishes case reports related to breast cancer, lung cancer, gastrointestinal cancer, skin cancer, head and neck cancer, paediatric oncology, neurooncology as well as genitourinary cancer.
Bartonellosis is an emerging infectious bacterial disease in dogs, caused by the gram-negative bacteria Bartonella, which may affect cats and humans as well.
Results The patient, offspring of an unrelated Caucasian couple with uneventful past medical history, presented with erythematous papular rash, biquotidian fever, night sweats and arthralgias. There was no antecedent history of foreign travel or contact with animals. Investigations showed increased inflammatory markers (ESR 86,CRP 80 [range 0-10mg/dl)], thrombocytosis, hypercalcemia and raised ALP and angiotensin converting enzyme(ACE). Quantiferon test was negative. Abdominal imaging (USS followed by MRI) showed multifocal calcified granulomas of the liver and spleen, chest radiograph showed enlarged hilar lymph nodes; ophthalmology review showed low grade panuveitis. Diffrentials included systemic JIA, small vessel vasulitides and sarcoidosis. Clinical, laboratory and imaging features pointed towards sarcoidosis. However, subsequent raised titers (IgM 1:32, IgG 1:256) against bartonella confirmed the diagnosis of B. henselae infection. She tested negative for HIV1+2 and lymphocyte subset ...
All animal bites need to be properly cleaned, and most need treatment based on the type and severity of the wound. Whether the bite is from a family pet or an animal in the wild, scratches and bites can become infected and cause scarring. Animals can also carry diseases that can be transmitted through a bite. Bites that break the skin and bites of the scalp, face, hand, wrist, or foot are more likely to become infected. Cat scratches, even from a kitten, can carry "cat scratch disease," a bacterial infection.. Other animals can transmit rabies and very rarely tetanus. Rodents such as mice, rats, squirrels, chipmunks, hamsters, guinea pigs, gerbils, and rabbits are at low risk of carrying rabies, but they can transmit other diseases.. The most common type of animal bite is a dog bite. Follow these guidelines to help decrease the chance of your child being bitten by an animal:. ...
With Bartonella, theres what I know as as Lyme patient and what I read on the internet. Tonight I read a little bit about Bartonella. It turns out that in other settings besides the ones where people with tick-borne illnesses congregate, it has its own other life. There are a few things I didnt realize.…
How to Put Out the Fire in Your Burning Bartonella Feet For people diagnosed with Bartonella that have painful, burning, tingling feet by Greg Lee You
Cat Scratch Fever, Chronic Abdominal Pain, Loss of Appetite Symptom Checker: Possible causes include Gastric Ulcer, Peptic Ulcer, Ulcerative Colitis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Cat Scratch Fever has a familiar paranormal set up. The heroine, Lilly, is a lynchat (werelynx) and is going into heat. This is inconvenient for her because shes trying to broker a business deal for land with the hero, Dante, who is a werewolf. The werewolves and werelynxes hate each other because werewolves stole the werelynx land years ago and wont sell it back to them.. The set up promises sexy fun and delivers. In one of the very first scenes, Lillys overcome with lust from the heat so she pulls her car over and masturbates to relieve the sensation. Naturally the hero stumbles upon her and cannot help but watch. Writing up the description, it sounds a bit heavy-handed but I thought it was well done.. Lilly is a decent heroine. She wants the land back and will do anything to get it. Shes a bit headstrong and mouthy, but not in a way that makes me roll my eyes. She refuses to take crap from anyone, especially the werewolves. Dante is the alpha of the werewolf pack and hes not an ...
We used a whole-genome scanning technique to identify the NADH dehydrogenase gamma subunit (species in a wide range of environmental samples yet maintains minimal cross-reactivity to mammalian host and arthropod vector organisms. been shown to cause disease in humans including Carrions disease (13) cat scratch disease (7 14 25 endocarditis (6 11 and recently a febrile illness in humans from Thailand (caused by species are considered potential emerging pathogens (1 26 28 identification requires the ability to detect bacteria in both mammalian hosts and arthropod vectors. Although bacterial culture is considered ideal the difficulty and time involved make it impractical for large-scale use. Additionally nucleic acid-based detection techniques may be hindered by inhibitors in environmental and clinical samples low sensitivity and the absence of genus-specific primers (10 27 To address these issues we used whole-genome scanning based on the complete genomes of to identify host- and vector-blind ...
*aids *ankylosing spondylitis *behcets disease *cat-scratch disease *crohns disease *cytomegalovirus (cmv) *eye injury *fungal or parasite infections *herpes simplex virus, which causes cold
Buy Bremon Online! Bremon also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), cryptosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires disease, (type of lung in...
Myzocytosis "Bartonella henselae" (PDF). Dramsi, Shaynoor; Cossart, Pascale (2002-03-18). "Listeriolysin O". The Journal of ... Bacterial examples include: Bartonella henselae Francisella tularensis Listeria monocytogenes Salmonella Typhi Brucella ...
Axel Schmidt (1998). Bartonella and Afipia species emphasizing Bartonella henselae. Basel, New York: Karger. ISBN 3-8055-6649-2 ...
"Bartonella henselae" (PDF).. .mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes ...
Lyme disease or Bartonella henselae may also cause encephalitis.[citation needed] Other bacterial pathogens, like Mycoplasma ...
Aeromonas hydrophila Alcaligenes xylosoxidans Bartonella henselae Bordetella pertussis (pertussis) Brucella spp. Burkholderia ...
Bartonella henselae: BH11960". KEGG Database. [2]. Aslmark, C.M., et al. 2004. The louse-borne human pathogen Bartonella ... Bartonella henselae hypothetical protein 11960 (BH11960) is encoded by the BH11960 gene. This hypothetical protein is conserved ... "Hypothetical protein BH11960 (Bartonella henselaei str. Houston-1". [1]. The function of the BH11960 protein is not known. ... The promoter is ubiquitously conserved in the other Bartonella species and contains a TATA box. BH11960 is the largest of the ...
It is caused by either Bartonella henselae or B. quintana. B. henselae is most often transmitted through a cat scratch or bite ... If a cat is carrying Bartonella henselae, then it may not exhibit any symptoms. Cats may be bacteremic for weeks to years, but ... Bacillary angiomatosis (BA) is a form of angiomatosis associated with bacteria of the Bartonella genus. Cutaneous BA is ... December 1997). "Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis". N. Engl. J ...
The BadA protein is another example of a TAA found in Bartonella henselae bacteria. Bartonella henselae is the causative agent ... Neisseria meningitidis UspA1 and A2 of Moraxella catarrhalis Hia and Hsf of Haemophilus influenzae BadA of Bartonella henselae ... "Structure of the head of the Bartonella adhesin BadA". PLoS Pathog. 4 (8): e1000119. doi:10.1371/journal.ppat.1000119. PMC ... Harms A, Dehio C (2012). "Intruders below the radar: molecular pathogenesis of Bartonella spp". Clin Microbiol Rev. 25 (1): 42- ...
... of Bartonella henselae". Infect. Immun. 73 (7): 4205-13. doi:10.1128/IAI.73.7.4205-4213.2005. PMC 1168562 . PMID 15972511. " ... A similar factor has been identified in Bartonella henselae. It can be used to identify Streptococcus agalactiae. Though not ...
It is also important for confirmation of Bartonella henselae, a causative organism in cat-scratch disease. Warthin-Starry ...
Bartonella quintana is closely related to Bartonella henselae, the agent of cat scratch fever and bacillary angiomatosis. The ... Bartonella quintana is transmitted by contamination of a skin abrasion or louse-bite wound with the faeces of an infected body ... Ohl, M. E.; Spach, D. H. (1 July 2000). "Bartonella quintana and Urban Trench Fever". Clinical Infectious Diseases. 31 (1): 131 ... Comer, James A. (25 November 1996). "Antibodies to Bartonella Species in Inner-city Intravenous Drug Users in Baltimore, Md". ...
Cat-scratch disease is caused by Bartonella henselae and Bartonella quintana from fleas which are endemic in cats. Toxocariasis ...
... henselae (originally known as Rochalimea henselae before the genera Bartonella and Rochalimea were combined) and B. ... Bartonella henselae is a fastidious, intracellular, Gram-negative bacteria. The cat was recognized as the natural reservoir of ... Cat-scratch disease (CSD) is a common and usually benign infectious disease caused by the bacterium Bartonella henselae. It is ... Higgins JA, Radulovic S, Jaworski DC, Azad AF (1996). "Acquisition of the cat scratch disease agent Bartonella henselae by cat ...
2004). "The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae". ...
Bacterial causes associated with TM include mycoplasma pneumoniae, Bartonella henselae, and the types of borrelia that cause ...
Bartonella henselae bacilli in cardiac valve of a patient with blood culture-negative endocarditis. The bacilli appear as black ...
Spinella found that one patient with bartonella henselae also had anti-cardiolipin antibodies, suggesting that bartonella may ... Beyond cat scratch disease: a case report of bartonella infection mimicking vasculitic disorder. Case Rep Infect Dis. 2012;2012 ...
Acute hepatitis is caused by Neisseria meningitidis, Neisseria gonorrhoeae, Bartonella henselae, Borrelia burgdorferi, ...
It is used to find the organisms that cause cat-scratch disease (Bartonella henselae) and syphilis (Treponema pallidum) and ...
Cat-scratch disease is an infection caused by the bacterial organism Bartonella henselae, typically acquired by a scratch from ...
The study found the most prevalent infection to be Bartonella henselae, the cause of cat-scratch disease in humans, with 33.6% ...
... in Bartonella species (i.e. B. henselae, B. clarridgeiae, B. tribocorum, B. quintana, B. bacilliformis, B. grahamii), in ... Bartonella species (i.e. B. henselae, B. clarridgeiae, B. tribocorum, B. quintana, B. bacilliformis, B. grahamii). All these ... In Bartonella species the αr45 upstream gene was always found to code for a protein containing a rhodanase domain. In the ... This analysis also revealed an extended conserved sequence stretch among the promoters of the Brucella and Bartonella αr45 sRNA ...
Bartonella henselae. The eight edition (1955) erroneously listed actinomycosis as a fungal disease. In the ninth edition, ...
cause septic spinal arthritis Eikenella corrodens - human bites Pasteurella multocida, bartonella henselae - animal bites or ...
The bites from cats can infect a person with: Cat-scratch disease, caused by the bacterium Bartonella henselae)Cat-scratch ... The resident flora in the mouth of the cat includes Pasteurella, Staph, Bartonella, and Streptococcus species. Bites from cats ...
Cat-scratch disease is caused by Bartonella henselae and Bartonella quintana from fleas which are endemic in cats. Toxocariasis ... Bartonella henselae cats bites or scratches from infected cats Chagas disease Trypanosoma cruzi armadillos, Triatominae ( ...
Parte, A.C. "Bartonella". www.bacterio.net. "Bartonella henselae". NCBI Taxonomy Browser. 38323. Type strain of Bartonella ... PMC 3657863 . Bernard La Scola; Didier Raoult (17 March 1999). "Culture of Bartonella quintana and Bartonella henselae from ... Bartonella henselae, formerly Rochalimæa, is a proteobacterium that is the causative agent of cat-scratch disease ( ... bartonellosis). B. henselae is a member of the Bartonella genus, one of the most common types of bacteria in the world. It ...
... Sue Anne Brenner sbrenne at emory.edu Thu Apr 11 10:36:39 EST 1996 *Previous message: bartonella henselae ... B. henselae grows reasonably well on rabbit blood agar plates. If plating blood, it may be easier to count colonies if the ... B. henselae can also grow in some cell lines, including vero cells and human epithelial cells. If yourre attempting to isolate ... B. henselae from blood, lysis tubes such as the Isolator may be superior to other methods. For other body substances, there are ...
Rochalimaea henselae. Other names i. ›ATCC 49882. ›ATCC:49882D-5. ›Bartonella henselae (Regnery et al. 1992) Brenner et al. ...
hypothetical protein Q655_00693 [Bartonella henselae JK 51] hypothetical protein Q655_00693 [Bartonella henselae JK 51]. gi, ...
Cats do have the capacity to spread Bartonella henselae to humans. Kittens pose a greater risk than cats and pass the bacterium ... At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. Cats who are ... There have been reports of Bartonella henselae found inside fleas, however, there have been no instances of flea bites causing ... Cat Scratch Disease (Bartonella henselae Infection) Commonly abbreviated as CSD, Cat Scratch Disease is an infectious disease ...
Cat scratch disease (CSD) is a common zoonosis in children caused by Bartonella henselae (B. henselae). Typical CSD, which ... Bartonella henselae Infection: An Uncommon Mimicker of Autoimmune Disease. Despoina N. Maritsi,1,2 Diagoras Zarganis,2 Zoi ... R. F. Jacobs and G. E. Schutze, "Bartonella henselae as a cause of prolonged fever and fever of unknown origin in children," ... A. Sander, M. Posselt, N. Böhm, M. Ruess, and M. Altwegg, "Detection of Bartonella henselae DNA by two different PCR assays and ...
... Dionna M. Mathews,1 Katie M. Vance,2 Pamela M. ... Y. Kodama, N. Maeno, J. Nishi et al., "Multifocal osteomyelitis due to Bartonella henselae in a child without focal pain," ... I. Pons, I. Sanfeliu, N. Cardenosa, M. M. Nogueras, B. Font, and F. Segura, "Serological evidence of Bartonella henselae ... K. Mazur-Melewska, K. Jonczyk-Potoczna, A. Mania et al., "The significance of Bartonella henselae bacteria for oncological ...
... ,ARUP Laboratories is a national reference laboratory and a ... Bartonella Culture. 2. Bartonella DNA, Tissue, PCR. 3. Bartonella DNA, PCR. 4. Bartonella henselae Antibody, IgG by IFA. 5. ... Bartonella quintana Antibody, IgM by IFA. 8. Bartonella quintana Antibody, IgG by IFA. 9. Culture, Bartonella. 10. Adenovirus ... Bartonella quintana Antibodies, IgG & IgM by IFA. 6. Bartonellahenselae Antibody, IgM by IFA. 7. ...
Bartonella henselae is a member of the class of the Bartonella genus, one of the most common type of bacteria in the world. ... Bartonella henselae is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis ... Peliosis hepatis caused by B. henselae can occur alone or develop with cutaneous bacillary angiomatosis or bacteremia. Patients ... Retrieved from "https://www.wikidoc.org/index.php?title=Bartonella_henselae&oldid=1353922" ...
... we demonstrated that HemS from Bartonella henselae expressed in E. coli allows the release of iron from heme. Purified HemS ... For Bartonella, the gene cluster devoted to the synthesis of the complete heme uptake system also contains a gene encoding for ... Therefore, Bartonella genome encodes for a complete heme uptake system allowing the transportation of this compound across the ... Heme has been proposed to be used as an iron source for Bartonella since these bacteria do not synthesize a complete system ...
Bartonella henselae [bär′′ tə-nel′ə henz′ ə-lā] On This Page ... It was later called Bartonella bacilliformis.. The species B. henselae was named after Diane Hensel, a technologist in the ... Bartonella henselae . Emerging Infectious Diseases. 2008;14(6):980. doi:10.3201/eid1406.080980.. ... The organism was first named Rochalimaea henselae and then B. henselae, when sequencing showed identity with that genus. ...
Bartonella henselae. Mutation(s): 0 Gene Names: invB, BH01650. Find proteins for A0A0H3LVG3 (Bartonella henselae (strain ATCC ... Crystal Structure of Invasion Associated Protein B from Bartonella Henselae.. Patskovsky, Y., Ozyurt, S., Freeman, J., Slocombe ... Crystal structure of invasion associated protein b from bartonella henselae. *DOI: 10.2210/pdb3DTD/pdb ...
A library of Bartonella henselae DNA was screened with antibody raised to the bacteriophage particle associated with this ... Analysis of 36-kilodalton protein (PapA) associated with the bacteriophage particle of Bartonella henselae.. Anderson B1, ... Taken together, these results suggest that papA is present on a mobile genetic element of the B. henselae genome and is also ... A papA-specific probe hybridized to multiple bands of B. henselae genomic DNA digested with several different restriction ...
... henselae SA2; 3, B. henselae Houston-1; 4, B. henselae URBHLLY8; 5, B. henselae URBHLIE9; 6, B. henselae Cat6; 7, B. henselae ... Coinfection with Bartonella clarridgeiae and Bartonella henselae and with different Bartonella henselae strains in domestic ... Prevalence of Bartonella henselae and Bartonella clarridgeiae in stray cats. J. Clin. Microbiol.35:1327-1331. ... Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). J. Clin. ...
Abcam provides specific protocols for Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) : ...
Anti-Bartonella henselae (Cat Scratch Fever) antibody [H2A10] (ab704) has been cited in 4 publications. Find out more about the ... Johnson R et al. Identification of Bartonella henselae in an aborted equine fetus. Vet Pathol 46:277-81 (2009). PubMed: ... Vermi W et al. Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma. Blood 107:454 ... Maggi RG et al. Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure. Parasit Vectors 6 ...
Splenorenal Manifestations of Bartonella henselae Infection in a Pediatric Patient.(Case Report, Report, Case study) by Case ... It was only as recently as 1992 that the pathogen Bartonella henselae was isolated [5]. Bartonella henselae is an intracellular ... the Bartonella henselae IgG was positive at ,1:1024, consistent with presence of IgG antibody to Bartonella henselae, ... these endothelial cells promote proliferation of Bartonella henselae [11]. The clinical presentation of Bartonella henselae ...
Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... Bartonella henselae participates in host recognition by the type IV secretion system as a homolog of the virB5 family. ... Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... It has been found that up to 95% of patients with Cat Scratch Disease show antibodies against Bartonella henselae antigens. ...
Bartonella 26kDa is expressed with a -10x His tag at N-terminus. Bartonella henselae of outer membrane protein p26 has an ... Recombinant Bartonella Henselae 26kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular ... important nucleotide identity with orthologs in Bartonella spp, Brucella spp in addition to more than a few plant-associated ... Bartonella henselae of outer membrane protein p26 has an important nucleotide identity with orthologs in Bartonella spp, ...
The 16S-23S intergenic transcribed spacer region obtained from each porpoise was 99.8% similar to that of B. henselae strain ... Currently, the geographic distribution, mode of transmission, reservoir potential, and pathogenicity of bloodborne Bartonella ... we directly amplified Bartonella species DNA from blood of a harbor porpoise stranded along the northern North Carolina coast ... We report detection of Bartonella henselae DNA in blood samples from 2 harbor porpoises (Phocoena phocoena). By using real-time ...
Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats.. ... To elucidate kinetics of Bartonella henselae bacteremia and IgG response, evaluate antibiotic therapy, and investigate ... Cats were inoculated with B henselae or B quintana and monitored. Convalescent cats were challenge exposed with B henselae. ... On challenge exposure to B henselae, cats previously infected with B henselae remained abacteremic; cats previously inoculated ...
Bartonella henselae). Cat scratch disease (CSD), also called cat scratch fever, is a bacterial infection caused by Bartonella ... Reporting Cat Scratch Disease (Infection Caused by Bartonella spp.) Healthcare providers and clinical laboratories are required ... henselae, which is generally spread to people through cat bites or scratches. Most healthy people do not develop any symptoms, ...
Purpose: To report an unusual case of Bartonella henselae neuroretinitis (BHNR) in a patient with myelinated retinal nerve ... Neuroretinitis Secondary to Bartonella Henselae in a Patient with Myelinated Retinal Nerve Fibers: Diagnostic Dilemmas and ...
Bartonella henselae is the major etiological agent of cat scratch disease in humans. Cats act as the natural reservoir of B. ... Prevalence of Bartonella henselae in Italian stray cats: evaluation of serology to assess the risk of transmission of ... Prevalence of Bartonella henselae in Italian Stray Cats: Evaluation of Serology To Assess the Risk of Transmission of ... henselae and can transmit the infection to humans by a bite or scratch. The prevalence of B. henselae in cat populations was ...
We used a membrane-feeding technique to infect I. ricinus with B. henselae and demonstrate transmission of B. henselae within I ... henselae from ticks to blood. These results provide evidence that I. ricinus is a competent vector for B. henselae. ... B. henselae causes cat-scratch disease and is increasingly associated with several other syndromes, particularly ocular ... Cats are the main reservoir for B. henselae and the bacteria are transmitted to cats by cat fleas. However, new potential ...
  • A library of Bartonella henselae DNA was screened with antibody raised to the bacteriophage particle associated with this organism. (nih.gov)
  • The kinetics of IgG and IgM antibody production were studied in 18 patients with CSD on the basis of a positive B. henselae IFA IgM serology. (asm.org)
  • serology was performed by indirect fluorescent antibody testing and confocal laser scanning microscopy was used to visualize B. henselae organisms in resected brain. (biomedcentral.com)
  • The cloned gene was expressed in Escherichia coli , and the purified Pap31 protein elicited strong antibody responses in mice and was reactive with rabbit anti-live B. henselae and mouse anti-Pap31 antibodies by Western blotting. (asm.org)
  • Although IFAs have a high sensitivity for Bartonella antibody detection, they have various limitations including cross-reactivity with other closely-related human pathogens. (scielo.org.za)
  • All B. henselae strains were found positive with this antibody. (abcam.cn)
  • Bartonella henselae is now well established as a significant human pathogen and is possibly the agent of the world's most common bacterial zoonosis acquired from a companion animal. (asm.org)
  • B. henselae is another cosmopolitan emerging human pathogen. (cdc.gov)
  • Other Bartonella -flea associations are apparent: for example, 61% of rat fleas ( Xenopsylla cheopis ) were found infected with bartonellae, including a known human pathogen, B. elizabethae ( 7 ). (cdc.gov)
  • To determine whether Bartonella henselae is present in questing Ixodes ricinus ticks, we analyzed the prevalence of B. henselae DNA among tick stages compared to the prevalence of DNA from Borrelia burgdorferi sensu lato, the pathogen most frequently transmitted by ticks. (asm.org)
  • Cats are a confirmed reservoir host of B. henselae transmitting the pathogen by cat scratches or bites. (asm.org)
  • The Gram-negative bacterium Bartonella henselae (Bh) is an emerging zoonotic pathogen that has been associated with a variety of human diseases including bacillary angiomatosis which is characterized by vasoproliferative tumor-like lesions on the skin and internal organs of some immunosuppressed individuals. (usf.edu)
  • We report the development of a microarray comprised of proteins expressed from 96% (1433/1493) of the predicted ORFs encoded by the genome of the zoonotic pathogen Bartonella henselae. (escholarship.org)
  • Bartonella henselae is a gram-negative, zoonotic pathogen with world-wide distribution. (biomedcentral.com)
  • The study of 16S rRNA gene sequences of all isolates of Bartonella henselae obtained in our laboratory and others from human patients or cats has revealed two genotypes according to the sequence of the 16S rRNA gene. (asm.org)
  • Houston-1, 90-615, and SA2 strains showed the same patterns in SDS-PAGE, but they differed from the patterns of B. henselae isolates URBHLLY8, URBHLIE9, Cat6, Fizz, and CAL-1. (asm.org)
  • The authors found that two isolates of B. henselae , from a patient with endocarditis and a patient with CSD, were genetically different from all previously isolated strains by sequence analysis of the 16S rRNA-encoding gene. (asm.org)
  • PCR-based RFLP analysis of the 16S-23S rRNA intergenic spacer region using Alu I and Hae III demonstrated seven composite RFLP types in 11 B. henselae isolates from patients with BA, septicemia, and parenchymal bacillary peliosis ( 26 ). (asm.org)
  • 34 ) identified five different fingerprint profiles from 17 isolates of B. henselae isolated from cats and from tissue and blood of human immunodeficiency virus-infected patients and patients with CSD. (asm.org)
  • The molecular typing of the isolates showed that 20.6% of bacteremic cats were infected with B. henselae type I strain, 61.1% were infected with B. henselae type II, and 18.3% were coinfected with both. (nih.gov)
  • We attempted to resolve this issue and extend exploration of the population structure of B. henselae by using multilocus sequence typing (MLST) to examine the distribution of polymorphisms within nine different genes in a sample of 37 human and feline isolates. (asm.org)
  • Genotypic analyses of B. henselae isolates using a variety of different pangenomic or locus-specific typing approaches have identified a number of genetic groupings. (asm.org)
  • We have recently demonstrated the appropriateness of pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) for differentiation of B . henselae isolates to the strain level ( 10 , 11 ). (cdc.gov)
  • Therefore, we analyzed the clonal relationship between sequential B . henselae isolates that were obtained at different times from the blood of 2 cats to determine whether recurrences were caused by the initial strain or a new strain. (cdc.gov)
  • Sma I macrorestriction patterns of Bartonella henselae isolates from 2 cats. (cdc.gov)
  • The 16S rRNA type was determined for 49 B. henselae isolates. (asm.org)
  • Feline B. henselae isolates are genetically diverse ( 2 , 11 , 16 , 19 , 22 , 26 - 29 ). (asm.org)
  • The BAPGM platform consists of PCR amplification of Bartonella DNA from the patient's extracted blood and serum samples before, and after BAPGM enrichment culture and from isolates, if obtained, following subculture of pre-enriched samples onto blood agar plates. (biomedcentral.com)
  • The specific name henselae honors Oklahoman microbiologist Diane Marie Hensel (b. 1953), who collected numerous strains and samples of the infective agent during an outbreak in Oklahoma in 1985. (wikipedia.org)
  • Nine monoclonal antibodies derived from BALB/c mice immunized with B. henselae Houston-1 strain reacted only with strains Houston-1, 90-615, and SA2, and not with any other Bartonella strains. (asm.org)
  • Study of 22 additional strains of B. henselae isolated from French bacteremic cats demonstrated that they all belong to one or the other of the proposed serotype or genotype. (asm.org)
  • The inheritances of several of the genes studied could not be reconciled with one another, providing further evidence of horizontal gene transfer among B. henselae strains and suggesting that recombination has a role in shaping the genetic character of bartonellae. (asm.org)
  • A subset of 31 of these cats also had whole blood collected to tentatively isolate Bartonella strains. (ajtmh.org)
  • At some point in their lifetimes, approximately forty percent of cats become carriers of the Bartonella henselae. (medic8.com)
  • Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. (nih.gov)
  • Convalescent cats were challenge exposed with B henselae. (nih.gov)
  • Long-duration, high-titer B henselae infections were highly reproducible in cats. (nih.gov)
  • In these studies, the question whether the cats were still infected by the initial B . henselae strain or had acquired a new strain was not addressed. (cdc.gov)
  • It was concluded that the cats were persistently infected with B . henselae ( 8 ). (cdc.gov)
  • Bartonella henselae and B. clarridgeiae were isolated from 19 (61%) of these cats. (ajtmh.org)
  • Bartonella henselae type I was isolated from 17 (89%) of the 19 culture-positive cats. (ajtmh.org)
  • Six cats (31%) were infected with B. clarridgeiae, of which four were coinfected with B. henselae. (ajtmh.org)
  • When tested by enzyme immunoassay (EIA), 67 cats (62.6%) had antibodies to B. henselae and 71 cats (66.4%) had antibodies to B. clarridgeiae. (ajtmh.org)
  • Domestic cats are considered reservoirs and vectors for human infections with B. henselae ( 5 , 15 , 31 , 36 ) and for B. clarridgeiae . (asm.org)
  • A study of cats living in and around Paris, France, showed that of 57 cats infected with B. henselae , 41 were infected with rRNA type II, 14 were infected with rRNA type I, and 2 were coinfected with rRNA types I and II. (asm.org)
  • In addition, eight cats were infected with B. clarridgeiae and B. henselae and 15 with B. clarridgeiae only ( 9 ). (asm.org)
  • B. henselae was detected in the peripheral blood of a wide range of mammals including domestic (e.g., cats, dogs, and horses) and wild animals (e.g., porpoise, lions, cheetahs, and wild felids). (asm.org)
  • Among 471 cat serum samples collected from 7 veterinary clinics in Kanagawa and Saitama Prefectures, 9.1% (41/471) and 8.7% (41/471) of cats harbored antibodies against Bartonella henselae and Toxoplasma gondii, respectively. (nii.ac.jp)
  • Publications] Maruyama, S.他5名: 'Prevalence of Bartonella henselae, Bartonella clarridgeiae and the 16SrRNA Gene Types of Bartonella henselae among Pet Cats in Japan'J.Vet.Med.Sci. (nii.ac.jp)
  • Publications] Maruyama, S.他10名: 'Seroprevalence of Bartonella henselae and Toxoplasma gondii infections among pet cats in Kanagawa and Saitama Prefectures'J.Vet.Med.Sci. (nii.ac.jp)
  • Participants who had raised cats showed 22.2% seropositivity against B. henselae , and those with no experience with cats showed 13.7% seroprevalence ( p = 0.17). (kjim.org)
  • Participants who had cats as pets or been scratched by cats, showed 9.8% seropositivity against B. henselae (IFA titer ≥ 1:256). (kjim.org)
  • Approximately, 16% to 43% of specimens (i.e., blood, nail, and saliva) from dogs and cats were positive for B. henselae , as confirmed by PCR [ 3 ]. (kjim.org)
  • In conclusion, findings of this study showed the prevalence of B. henselae in Iranian cats which is important due to its public health issues, especially for the immunocompromised pet owners. (iranjournals.ir)
  • Cats can get infected with B. henselae from flea bites and flea dirt (droppings) getting into their wounds. (cdc.gov)
  • Stray cats may be more likely than pets to carry Bartonella . (cdc.gov)
  • The CDC estimates that about 40 percent of all cats bring Bartonella henselae at some time in their life. (ehealthglobalhealth.com)
  • Multi-locus sequence typing (MLST) identified the strain genotype as sequence type 5, commonly found zoonotic B. henselae strain in cats. (biomedcentral.com)
  • Pathogenesis of Bartonella Henselae in the Domestic Cat: Use of a PCR-based Assay for the Detection and Differentiation of B. Henselae Genotype I and Genotype II in Chronically Infected Cats. (lsu.edu)
  • Bartonella henselae LSU 16 genotype II, Bartonella henselae Baby genotype II, Bartonella henselae 87--66 genotype I, and Bartonella henselae Houston-1 genotype I were used in this study to infect cats. (lsu.edu)
  • Of the twenty-three cats examined, Bartonella DNA was detected in various tissues from 10 of the 23 cats. (lsu.edu)
  • The spleen of nine of the 10 cats was positive for Bartonella DNA. (lsu.edu)
  • RNA expression analysis using the RT-PCR assay with primers specific for the 16S rRNA and the citrate synthase gene (gltA) of Bartonella detected no Bartonella RNA expression in the tissue of infected cats. (lsu.edu)
  • B. henselae genotype I was not detected in any of the infected cats. (lsu.edu)
  • Bartonella koehlerae is a proteobacterium first isolated from cats. (wikipedia.org)
  • Cats could be infected with B. henselae through intradermal inoculation using flea feces containing B. henselae. (wikipedia.org)
  • These interactions may be important initial steps leading to bacterial attachment and colonization that promote the establishment of B. henselae infections in vivo. (asm.org)
  • B. henselae Pap31 was originally described as a bacterial surface protein that is associated with the bacteriophage-like particle from B. henselae ( 6 ). (asm.org)
  • Bacterial examples include: Bartonella henselae Francisella tularensis Listeria monocytogenes Salmonella Typhi Brucella Legionella Mycobacterium Nocardia Rhodococcus equi Yersinia Neisseria meningitidis Fungal examples include: Histoplasma capsulatum. (wikipedia.org)
  • Recombinant Bartonella Henselae 17kDa produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 18kDa. (prospecbio.com)
  • Serological and molecular studies demonstrated that Bartonella henselae is the etiologic agent in most cases of CSD. (asm.org)
  • In an effort to overcome limitations associated with the molecular detection and isolation of Bartonella spp. (biomedcentral.com)
  • In addition, utilization of the BAPGM enrichment blood culture platform has facilitated the isolation or molecular detection of other Bartonella spp. (biomedcentral.com)
  • The exact molecular functions of these pathogenicity factors and their contribution to an orchestral interplay need to be analyzed to understand B. henselae pathogenicity in detail. (biomedcentral.com)
  • Molecular assessments showed that five samples out of 70 nail samples (7.14%) and one sample out of 70 saliva samples (1.42%) were genetically positive for B. henselae . (iranjournals.ir)
  • The purpose of this research is to contribute to the understanding of the pathogenesis of B. henselae in the domestic cat using a molecular approach. (lsu.edu)
  • Molecular Characterization of Bartonella vinsonii subsp. (wikipedia.org)
  • The 16S-23S intergenic transcribed spacer region obtained from each porpoise was 99.8% similar to that of B. henselae strain San Antonio 2 (SA2), whereas both heme-binding phage-associated pap 31 gene sequences were 100% homologous to that of B. henselae SA2. (cdc.gov)
  • The least common reactivity found in this study was against the B. henselae Marseille strain. (cdc.gov)
  • Three of these patients reacted to B. henselae Berlin1, and 1 reacted to the Houston-1 strain. (cdc.gov)
  • We found that 7.3% of the B. henselae proteins on the microarray were seroreactive and that seroreactivity was not evenly distributed between predicted protein function or subcellular localization. (escholarship.org)
  • Through a type IV secretory system, B. henselae proteins are transported into the host cells. (diarect.com)
  • The first is the VirB/VirD4 type IV secretion system that is responsible for delivering the bartonella effector proteins (Beps A-G) that act on endothelial cells in varying capacities. (grantome.com)
  • Neuroretinitis Secondary to Bartonella Henselae in a Patient with Myelinated Retinal Nerve Fibers: Diagnostic Dilemmas and Treatment. (nih.gov)
  • To report an unusual case of Bartonella henselae neuroretinitis (BHNR) in a patient with myelinated retinal nerve fibers (MRNFs). (nih.gov)
  • In another study, B . henselae was isolated from the blood culture of a cat of a patient who had an episode 2.5 years earlier of debilitating fatigue with a duration of 1 month and without fever or lymphadenopathy ( 7 ). (cdc.gov)
  • 13 ] reported that 38.7% of patients with lymphadenopathy showed high titers of B. henselae immunoglobulin G (IgG) (≥ 1:128). (kjim.org)
  • B. henselae is likely to be present throughout the country, since a survey of serum samples from 268 Croatian patients with lymphadenopathy showed that 37.7% patients had IgG antibodies against B. henselae [ 9 ]. (biomedcentral.com)
  • Apart from typical CSD, B. henselae has been recognized as a rare cause of fever of unknown origin (FUO) [ 1 ]. (hindawi.com)
  • Among those who seroconverted for B. henselae, 1 had fever and only 2 reported having been scratched. (cdc.gov)
  • Our findings add to the accumulating data on R. felis , B. henselae, and B. clarridgeiae and should alert medical workers in New Zealand, a common tourist destination, to the possibility that their patients may be infected with these organisms. (cdc.gov)
  • Thus, the gene is present in multiple copies on the genome or in different arrangements within a given population of B. henselae cells. (nih.gov)
  • Initially, blood samples were screened by using real-time PCR targeting the Bartonella 16S-23S RNA intergenic spacer (ITS) region, or the heme-binding phage-associated gene pap 31 ( 27 ). (cdc.gov)
  • Additionally, the performance of a Bartonella PCR hybridization assay based on the 16S rRNA gene was determined and compared with those of the serologic assays. (asm.org)
  • Two different B. henselae types based on partial 16S rRNA gene sequences have been described ( 3 ), with multiple DNA fingerprint patterns identified for each type ( 29 ). (asm.org)
  • A specific primer pair was derived from the B henselae 16S ribosomal RNA gene fragment. (jamanetwork.com)
  • Bartonella henselae hypothetical protein 11960 (BH11960) is encoded by the BH11960 gene. (wikipedia.org)
  • Although usually used to identify group "B", there is some evidence that the CAMP factor gene is present in several groups of streptococci, including group "A". A similar factor has been identified in Bartonella henselae. (wikipedia.org)
  • If your're attempting to isolate B. henselae from blood, lysis tubes such as the Isolator may be superior to other methods. (bio.net)
  • These analyses have been applied not only to epidemiological investigations of human B. henselae infections but also to broader surveys of human and feline isolate collections. (asm.org)
  • The DNA sequences were identical to each other and had 99.6% (456/457 bp) sequence similarity with B. henselae San Antonio 2 intergenic spacer region genotype (GenBank accession no. (cdc.gov)
  • A recent survey of Australian blood donors detected seropositivity in 5% of samples tested ( 7 ), and B. henselae was detected in the bloodstream of 10% of attendees at a South African AIDS clinic ( 14 ). (asm.org)
  • Flea infestation, adoption from a shelter or as a stray cat, hunting, and being from Florida or California were significant risk factors for B. henselae seropositivity. (asm.org)
  • Moreover, the seropositivity rates against B. henselae among healthy adults are 16.0% in Sweden, 8.7% in Spain, and 19.6% in China [ 8 - 10 ]. (kjim.org)
  • These observations suggest that B. henselae infections are commonly subclinical and/or markedly underreported, as problems with current diagnostic approaches are well recognized ( 13 , 24 , 25 , 27 ). (asm.org)
  • We used a membrane-feeding technique to infect I. ricinus with B. henselae and demonstrate transmission of B. henselae within I. ricinus across developmental stages, migration or multiplication of B. henselae in salivary glands after a second meal, and transmission of viable and infective B. henselae from ticks to blood. (cdc.gov)
  • Since this early study, the role of ticks in Bartonella spp. (cdc.gov)
  • If one considers that ixodid ticks feed only once per stage, Bartonella spp. (cdc.gov)
  • This process allowed us to definitively identify B. henselae (genotype Houston-1) DNA in the four ticks. (cdc.gov)
  • Ticks have been suspected to transmit Bartonella ( 25 ). (cdc.gov)
  • The odds of detecting B. henselae DNA in nymphal ticks was ∼14-fold higher than in adult ticks. (asm.org)
  • B. henselae DNA was detected in questing Ixodes pacificus and I. persulcatus ticks in North America, Eastern Europe, and Russia, respectively ( 4 , 13 , 14 , 22 , 25 ) and in I. ricinus ticks feeding on people or domestic animals in Central Europe ( 24 , 26 ). (asm.org)
  • Recently, ticks ( I. ricinus ) were experimentally infected with B. henselae . (asm.org)
  • 654 ticks were examined individually for the presence of DNA from Bartonella spp. (asm.org)
  • Aeromonas hydrophila Alcaligenes xylosoxidans Bartonella henselae Bordetella pertussis (pertussis) Brucella spp. (wikipedia.org)