Proto-oncogene proteins that are guanine nucleotide exchange factors for RHO GTPASES. They also function as signal transducing adaptor proteins.
Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.
Proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene (ONCOGENE PROTEINS, FUSION).
Proteins that control the CELL DIVISION CYCLE. This family of proteins includes a wide variety of classes, including CYCLIN-DEPENDENT KINASES, mitogen-activated kinases, CYCLINS, and PHOSPHOPROTEIN PHOSPHATASES as well as their putative substrates such as chromatin-associated proteins, CYTOSKELETAL PROTEINS, and TRANSCRIPTION FACTORS.
A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASE. This enzyme was formerly listed as EC 3.6.1.47.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
A sub-family of RHO GTP-BINDING PROTEINS that is involved in regulating the organization of cytoskeletal filaments. This enzyme was formerly listed as EC 3.6.1.47.
A CELL LINE derived from human T-CELL LEUKEMIA and used to determine the mechanism of differential susceptibility to anti-cancer drugs and radiation.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (ANTIGENS, CD3). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.
A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array of cellular functions including cytoskeletal changes, filopodia formation and transport through the GOLGI APPARATUS. This enzyme was formerly listed as EC 3.6.1.47.
Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.
A large family of MONOMERIC GTP-BINDING PROTEINS that are involved in regulation of actin organization, gene expression and cell cycle progression. This enzyme was formerly listed as EC 3.6.1.47.
A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR function.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
A mammalian homolog of the DROSOPHILA SON OF SEVENLESS PROTEIN. It is a guanine nucleotide exchange factor for RAS PROTEINS.
A rho GDP-dissociation inhibitor subtype that is highly expressed in hematopoietic cells and in LYMPHOCYTES. The expression of this subtype is associated with the regulation of CELL PROLIFERATION; TUMORIGENESIS; and APOPTOSIS.
Congenital open-angle glaucoma that results from dysgenesis of the angle structures accompanied by increased intraocular pressure and enlargement of the eye. Treatment is both medical and surgical.
Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.
A class of RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS that are genetically related to the Son of Sevenless gene from DROSOPHILA. Sevenless refers to genetic mutations in DROSOPHILA that cause loss of the R7 photoreceptor which is required to see UV light.
A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).
A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. This enzyme was formerly listed as EC 3.6.1.47.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membrane spanning sequence, producing immunoglobulins in the form of type I transmembrane proteins as opposed to secreted immunoglobulins (ANTIBODIES) which do not contain the membrane spanning segment.
A family of GUANINE NUCLEOTIDE EXCHANGE FACTORS that are specific for RAS PROTEINS.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
The recording of wavelike motions or undulations. It is usually used on arteries to detect variations in blood pressure.
An oncoprotein from the Cas NS-1 murine retrovirus that induces pre- B-CELL LYMPHOMA and MYELOID LEUKEMIAS. v-cbl protein is a tyrosine-phosphorylated, truncated form of its cellular homologue, PROTO-ONCOGENE PROTEIN C-CBL.
A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization.
Established cell cultures that have the potential to propagate indefinitely.
The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti).
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CERCOPITHECUS AETHIOPS).)
Physiologically inactive substances that can be converted to active enzymes.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
The blood-making organs and tissues, principally the bone marrow and lymph nodes.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A dynamic actin-rich extension of the surface of an animal cell used for locomotion or prehension of food.
Src-family kinases that associate with T-CELL ANTIGEN RECEPTOR and phosphorylate a wide variety of intracellular signaling molecules.
A subcategory of guanine nucleotide dissociation inhibitors that are specific for RHO GTP-BINDING PROTEINS.
Proto-oncogene proteins that negatively regulate RECEPTOR PROTEIN-TYROSINE KINASE signaling. It is a UBIQUITIN-PROTEIN LIGASE and the cellular homologue of ONCOGENE PROTEIN V-CBL.
Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
A subtype of dynamin found ubiquitously expressed in a variety of tissues.
The aggregation of soluble ANTIGENS with ANTIBODIES, alone or with antibody binding factors such as ANTI-ANTIBODIES or STAPHYLOCOCCAL PROTEIN A, into complexes large enough to fall out of solution.
Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development, suggesting that it may play a role in embryogenesis. In adult tissues high levels of the receptor are expressed in the LUNG; SKIN; SMALL INTESTINE and OVARY.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Enzymes that hydrolyze GTP to GDP. EC 3.6.1.-.
Serologic tests in which a positive reaction manifested by visible CHEMICAL PRECIPITATION occurs when a soluble ANTIGEN reacts with its precipitins, i.e., ANTIBODIES that can form a precipitate.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
A class of proteins involved in the transport of molecules via TRANSPORT VESICLES. They perform functions such as binding to the cell membrane, capturing cargo molecules and promoting the assembly of CLATHRIN. The majority of adaptor proteins exist as multi-subunit complexes, however monomeric varieties have also been found.
Protein factors that inhibit the dissociation of GDP from GTP-BINDING PROTEINS.
Retroviral proteins that have the ability to transform cells. They can induce sarcomas, leukemias, lymphomas, and mammary carcinomas. Not all retroviral proteins are oncogenic.
A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
Adherence of cells to surfaces or to other cells.
A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodimers. They interact with a wide variety of ligands including EXTRACELLULAR MATRIX PROTEINS; COMPLEMENT, and other cells, while their intracellular domains interact with the CYTOSKELETON. The integrins consist of at least three identified families: the cytoadhesin receptors(RECEPTORS, CYTOADHESIN), the leukocyte adhesion receptors (RECEPTORS, LEUKOCYTE ADHESION), and the VERY LATE ANTIGEN RECEPTORS. Each family contains a common beta-subunit (INTEGRIN BETA CHAINS) combined with one or more distinct alpha-subunits (INTEGRIN ALPHA CHAINS). These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development; HEMOSTASIS; THROMBOSIS; WOUND HEALING; immune and nonimmune defense mechanisms; and oncogenic transformation.
Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (ANTIGENS, CD3). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.
Specific molecular sites on the surface of B- and T-lymphocytes which combine with IgEs. Two subclasses exist: low affinity receptors (Fc epsilon RII) and high affinity receptors (Fc epsilon RI).
Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions. Reverse n-hybrid techniques refer to analysis for mutations or other small molecules that dissociate known interactions.
A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also sometimes dependent on CALCIUM. A wide range of proteins can act as acceptor, including VIMENTIN; SYNAPSINS; GLYCOGEN SYNTHASE; MYOSIN LIGHT CHAINS; and the MICROTUBULE-ASSOCIATED PROTEINS. (From Enzyme Nomenclature, 1992, p277)
Specialized structures of the cell that extend the cell membrane and project out from the cell surface.
Phosphatidylinositols in which one or more alcohol group of the inositol has been substituted with a phosphate group.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
Differentiation antigens expressed on B-lymphocytes and B-cell precursors. They are involved in regulation of B-cell proliferation.
The interfaces between T-CELLS and ANTIGEN-PRESENTING CELLS. Supramolecular organization of proteins takes place at these synapses involving various types of immune cells. Immunological synapses can have several functions including LYMPHOCYTE ACTIVATION; enhancing, balancing, or terminating signaling; or directing cytokine secretion.
Antisera used to counteract poisoning by animal VENOMS, especially SNAKE VENOMS.
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
A cell line derived from cultured tumor cells.
Stem cells from which B-LYMPHOCYTES; T-LYMPHOCYTES; NATURAL KILLER CELLS; and some DENDRITIC CELLS derive.
A continuous cell line of high contact-inhibition established from NIH Swiss mouse embryo cultures. The cells are useful for DNA transfection and transformation studies. (From ATCC [Internet]. Virginia: American Type Culture Collection; c2002 [cited 2002 Sept 26]. Available from http://www.atcc.org/)
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.
Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine with IMMUNOGLOBULIN Gs. Three subclasses exist: Fc gamma RI (the CD64 antigen, a low affinity receptor), Fc gamma RII (the CD32 antigen, a high affinity receptor), and Fc gamma RIII (the CD16 antigen, a low affinity receptor).
Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.
Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest.
A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
A guanine nucleotide exchange factor from DROSOPHILA. Sevenless refers to genetic mutations in DROSOPHILA that cause loss of the R7 photoreceptor which is required to see UV light.
Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
An ERYTHROLEUKEMIA cell line derived from a CHRONIC MYELOID LEUKEMIA patient in BLAST CRISIS.
The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL SURFACE RECEPTORS to MITOGEN-ACTIVATED PROTEIN KINASES.
Detergent-insoluble CELL MEMBRANE components. They are enriched in SPHINGOLIPIDS and CHOLESTEROL and clustered with glycosyl-phosphatidylinositol (GPI)-anchored proteins.
Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Proteins prepared by recombinant DNA technology.
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
Transport proteins that carry specific substances in the blood or across cell membranes.
Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Limbless REPTILES of the suborder Serpentes.
Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.
A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.
A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.
Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
... is a village in Vav Taluka of Banaskantha district in Gujarat, India. Morvada is said formerly to have belonged to ... It was under Palanpur Agency of Bombay Presidency, which in 1925 became the Banas Kantha Agency. After Independence of India in ... When Gujarat state was formed in 1960 from Bombay State, it fell under Banaskantha district of Gujarat. Morvada falls on ...
... is a village in Vav Taluka of Banaskantha district in Gujarat, India. Dhima was lapsed to Vav State in 1870. It was under ... When Gujarat state was formed in 1960 from Bombay State, it fell under tharad Taluka of Banaskantha district of Gujarat. ... Palanpur Agency of Bombay Presidency, which in 1925 became the Banas Kantha Agency. After Independence of India in 1947, Bombay ...
... is small but well developed village of Vav taluka of Banaskantha district in Gujarat. It is located at left bank of ...
It is located in Vav Taluka, in Banaskantha district and has a population of 2,600 (2011). The village has one primary school. ...
... is a small village located in Vav taluka in Banaskantha district in the Indian state of Gujarat. Mithavirana is old ... Gadhavi's are Jagirdar of nearby village Mithavi Charan and Mithavi Rana belong to then Princely state of Vav. v t e. ...
... and Sirohi districts and Mithavirana Vav Radhanpur region of Banaskantha North Gujarat. Its major tributaries are the Sukri, ...
... was a village in Vav Taluka of Banaskantha district in Gujarat, India, but it is now a Taluka of Banaskantha district in ... When Gujarat state was formed in 1960 from Bombay State, it fell under Banaskantha district of Gujarat. It is situated on a ... It was under Palanpur Agency of Bombay Presidency, which in 1925 became the Banas Kantha Agency. After Independence of India in ...
Mithi Vav, a stepwell is the oldest surviving monument of town. It is situated in the eastern part of the town. The five storey ... Palanpur is a city and a municipality of Banaskantha district in the Indian state of Gujarat. Palanpur is the administrative ... Rani ki vav, Patan Sun Temple, Modhera Dantiwada Dam Balaram Palace Resort Kedarnath Mahadev Temple, located in Jessore, about ... Subsequently Palanpur became the capital of Banaskantha district of Gujarat. Palanpur is located at 24°06′N 72°15′E / 24.10°N ...
At present, he is also active as the Chairman of the Banaskantha District Central Co-operative Bank and Banaskantha District ... He lost in 2017 Gujarat Legislative Assembly election from Vav against Indian National Congress candidate Geniben Thakor. He ... As Chaudhary was elected as the chairperson of Banaskantha District Cooperative Milk Federation at Palanpur, the 24-year reign ... He was elected unopposed as the chairman of Banaskantha District Cooperative Milk Federation, Palanpur (Banas Dairy). He also ...
... or VAV may refer to : Vav, Gujarat, a city and taluka in Gujarat Vav State, a princely state in Banas Kantha (Kathiawar) ... named after its above capital Vav (Vidhan Sabha constituency), Gujarat Vav (letter), a Semitic letter Vav (protein) VAV (band ... called vav in Gujarati and Marwari This disambiguation page lists articles associated with the title Vav. If an internal link ... a South Korean boy band Variable air volume, used in HVAC systems Varli language (ISO 639 code: vav), a language of India ...
The eight Vidhan Sabha segments are, Vav Tharad Dhanera Danta Palanpur Deesa Deodar Vadgam Kankrej Palanpur and Deesa, the two ... former MP for Banaskantha B. K. Gadhvi, former MP and Minister of State, Banaskantha Mukesh Gadhvi, former MP for Banaskantha ... Banaskantha District Central Co-operative Bank is one of the most important banks of Gujarat. It has got prestigious State ... Banaskantha district is one of the thirty-three districts of the Gujarat state of India. The administrative headquarters of the ...
Vav is a town and the headquarters of Wav Taluka in Banaskantha district in Gujarat state of India. Vav is the largest taluka ... So he chose his new capital, Vav. Vav gained its name from a step-well built by his great grandfather Rana Mehpalji. It ... The Rana, rulers of Vav, came from Sambhar and Nandol in Rajasthan, and claim kindred with Prithviraj Chauhan, who was defeated ... Wao State was under the Palanpur Agency of Bombay Presidency, which in 1925 became the Banas Kantha Agency. After Independence ...
Ambaji Temple - 18 km Kumbhariya Jain Temple - 22 km Koteshwar Shiv Temple - 30 km Taranga Jain Temple - 30 km Rani-Ki-vav, ... Danta is a city in the taluka of the same name in the Banaskantha district of the Indian state of Gujarat. It lies about 150 km ...
... is a stepwell located in Palanpur town of Banaskantha district, Gujarat, India. It is considered the only surviving ... "Tourism in Banaskantha(Palanpur), Best Places in Banaskantha(Palanpur)". www.tourismguideindia.com. Retrieved 23 January 2017. ... Mehta, R. N. (31 March 1977). "III: Explorations in the Banaskantha District". Archaeology of the Banaskantha district, North ... Idols embedded in walls View View Storeys viewed from above "પાલનપુરમાં મીઠીવાવની સફાઈ કરાઈ" [Mithi Vav of Palanpur cleaned]. ...
This district is located in northern Gujarat and bounded by Banaskantha district in the north and northeast, Mehsana district ... and Rani ki vav (a deep well). According to the 2011 census Patan district has a population of 1,343,734,[citation needed] ... Patan District was formed on 2-10-2000 from the parts of Mahesana and Banaskantha Districts. Patan District was formed ... Harij and Sami Talukas of Mahesana district and Radhanpur and Santalpur Talukas of Banaskantha District. The headquarter of the ...
Mithi Vav, a stepwell built around 8th century, is the only surviving architecture of the time of Parmar dynasty. According to ... Subsequently, Palanpur became the capital of Banaskantha district of Gujarat. Palanpur in early times is said to have been ... It subsequently became the capital of Banaskantha district of Bombay State. When Bombay State was bifurcated on linguistic ...
Vav assembly constituency is one of the 182 assembly constituency of Gujarat. It is located in Banaskantha District. This ... assembly seat represents the following segments, Vav Taluka Bhabhar Taluka Santalpur Taluka (Part) of Patan District Village - ...
In this way most of the smaller Tharad fiefs fell into the hands of Nadola Chauhans, cadets of the Vav house or of the old ... Tharad (historically known as Thirpur) is a town in Tharad taluka in the Banaskantha district of the state of Gujarat in India ... Compared with that of the Multani family, the cause of the Vav Rana was popular, and though for fear of drawing on themselves ... On growing up, her son Vajoji, returning to Tharad in 1244 built a stepwell, vav, and, successfully beating off the attacks of ...
The famous Rani ki vav ("Queen's Stepwell", probably 1063-83) is a very grand stepwell in Patan, Gujarat, once the Solanki ... Kumbharia Jain temples is a complex of five Jain temples in Kumbhariya, Banaskantha district built between 1062 - 1231 CE. The ... by 1140 Kiradu temples Rani ki vav, Patan, Gujarat, 11th century The five Dilwara Temples on Mount Abu are among the most ...
Wao State, modern Vav, was a 4th Class state. Its population in 1901 was 8,286 souls, residing in 26 villages and its area was ... Palanpur State itself was transferred to the Rajputana Agency in 1933, and the rest of the Banas Kantha Agency then merged with ... The designation of Palanpur Agency was changed to Banas Kantha Agency in 1925. ...
The Bhadrapad fair is held at Ambaji which is in the Danta Taluka of Banaskantha district, near the Gujarat-Rajasthan border. ... Rani ki vav 11th century CE.. Taranga Jain Temple constructed by Kumarapala (1143-1172 CE). ...
Vav assembly constituency is one of the 182 assembly constituency of Gujarat. It is located in Banaskantha District. This ... assembly seat represents the following segments, Vav Taluka Bhabhar Taluka Santalpur Taluka (Part) of Patan District Village - ...
Mithi Vav is a stepwell located in Palanpur town of Banaskantha district, Gujarat, India. It is considered the only surviving ... "Tourism in Banaskantha(Palanpur), Best Places in Banaskantha(Palanpur)". www.tourismguideindia.com. Retrieved 23 January 2017. ... Mehta, R. N. (31 March 1977). "III: Explorations in the Banaskantha District". Archaeology of the Banaskantha district, North ... Idols embedded in walls View View Storeys viewed from above "પાલનપુરમાં મીઠીવાવની સફાઈ કરાઈ" [Mithi Vav of Palanpur cleaned]. ...
Mithi Vav, a stepwell is the oldest surviving monument of town. It is situated in the eastern part of the town. The five storey ... Palanpur is a city and a municipality of Banaskantha district in the Indian state of Gujarat. Palanpur is the administrative ... Rani ki vav, Patan Sun Temple, Modhera Dantiwada Dam Balaram Palace Resort Kedarnath Mahadev Temple, located in Jessore, about ... Subsequently Palanpur became the capital of Banaskantha district of Gujarat. Palanpur is located at 24°06′N 72°15′E / 24.10°N ...
Largest searchable global B2C marketplace in Danta offering a complete range of Products from all Industry,Products Directory,Wholesale Products catalogs,India Products Manufacturers Exporters and Suppliers,buy quality products from top Sellers,Indian Branded Products Showroom and Store Showroom
Complete information of Banaskantha - List of Banks in Banaskantha - List of Hospitals in Banaskantha - Banaskantha MAP. List ... Vav. Post Office in Banaskantha. Aganwada. Agthala. Akoli. Alwada. Ambaji. Anapur Chhota. Antroli. Arkhi. Asara. Asarada. ... Banaskantha Gujarat PIN Code Banaskantha - : 407 Post Offices , 98 Banks , 166 Companies Registered . ... Un (Banaskantha). Undai. Undrana. Vachhadal. Vachhol. Vada. Vadgam. Vadgamda. Vadhana. Vagda. Vaghasan. Vaghrol. Vajapur Juna. ...
"Vav,Order:162,CanEdit:true,CanDelete:true},{Text:,Value:Veraval,Order:163,CanEdit ... "Banaskantha,Order:10,CanEdit:true,CanDelete:true},{Text:,Value:Bansada,Order:11, ...
The Bhadrapad fair is held at Ambaji which is in the Danta Taluka of Banaskantha district, near the Gujarat-Rajasthan border. ... Rani ki vav 11th century CE.. Taranga Jain Temple constructed by Kumarapala (1143-1172 CE). ...
Vav, Bharuch, Amod, Ankleshwar, Hansot, Jambusar, Jhagadia, Netrang, Vagra, Valia, Bhavnagar, Gariadhar, Ghogha, Jesar, Mahuva ... Banaskantha, Porbandar, Bhavnagar, Panchmahal, Surat, Vadodara, Dang, Rajkot, Junagadh, Devbhoomi Dwarka, Narmada, Chhota ... Vav, Bharuch, Amod, Ankleshwar, Hansot, Jambusar, Jhagadia, Netrang, Vagra, Valia, Bhavnagar, Gariadhar, Ghogha, Jesar, Mahuva ... Banaskantha, Porbandar, Bhavnagar, Panchmahal, Surat, Vadodara, Dang, Rajkot, Junagadh, Devbhoomi Dwarka, Narmada, Chhota ...
Nov 11: Ambaji Temple, Banaskantha. Nov 12: Wadinath Temple, Thara (Banaskantha). Nov 13: Vir Meghmaya Temple (Patan), ... Dec 8: Vav, Kalol, Himmatnagar, Nikol. Dec 9: Lunavada, Bodeli, Anand, Mehsana. Dec 10: Palanpur, Sanand, Kaalol, Vadodara. Dec ... Dec 9: Harij (Patan), Kanodar (Banaskantha), Vadnagar, Vijapur (Mehsana). Dec 10: Kheda, Aravali, Deodhar (Banaskantha, Kalol ( ... Nov 12: Palanpur (Banaskantha), Patan. Nov 13: Visnagar (Mehsana), Varana (Patan). Nov 24: Ahmedabad. Nov 25: Dahod. Nov 29: ...
She got married on Friday from the same shack in the compound of the Banaskantha District Collectorate in Palanpur that the 55- ... dismembered body had been found behind some bushes in Morikha village of Vav taluka, where the family lives. I will die here ...
Gujarat Industrial Policy 2020 - Classification (category) of talukas for various incentive schemes. For the purpose of Gujarat Industrial Policy 2020 released by the Government of Gujarat, the graded incentive is available for different talukas in each district. The following is the list of the same.. This list is updated as per notification of the state government dated 02-11-2020. To download the relevant notification you can follow this link. (Click Here). ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
Banaskantha. Danta Assembly FactbookTM Deesa Assembly FactbookTM Deodar Assembly FactbookTM Dhanera Assembly FactbookTM ... Palanpur Assembly FactbookTM Tharad Assembly FactbookTM Vav Assembly FactbookTM ...
  • Vav assembly constituency is one of the 182 assembly constituency of Gujarat. (wikipedia.org)
  • This assembly seat represents the following segments, Vav Taluka Bhabhar Taluka Santalpur Taluka (Part) of Patan District Village - Kesargadh Suigam Taluka 2007 - Parbat Patel, Bharatiya Janata Party 2012 - Shankar Chaudhary, Bharatiya Janata Party 2017 - Geniben Thakor, Indian National Congress "Gujarat: Order No. 33: Table-A: Assembly Constituency and Their Extent" (PDF). (wikipedia.org)
  • Mithi Vav is a stepwell located in Palanpur town of Banaskantha district, Gujarat, India. (wikipedia.org)
  • Archaeology of the Banaskantha district, North Gujarat upto 1500 A D (Part 1) (Thesis). (wikipedia.org)
  • Palanpur is a city and a municipality of Banaskantha district in the Indian state of Gujarat. (wikipedia.org)
  • Subsequently Palanpur became the capital of Banaskantha district of Gujarat. (wikipedia.org)
  • Idols embedded in walls View View Storeys viewed from above "પાલનપુરમાં મીઠીવાવની સફાઈ કરાઈ" [Mithi Vav of Palanpur cleaned]. (wikipedia.org)
  • Mithi Vav, a stepwell is the oldest surviving monument of town. (wikipedia.org)
  • She got married on Friday from the same shack in the compound of the Banaskantha District Collectorate in Palanpur that the 55-year-old has been living in for the past year, demanding that the upper-caste ''murderers'' of his son be brought to book. (ambedkar.org)