Bacteroides fragilis
Bacteroides
Prevotella melaninogenica
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium has been isolated from the mouth, urine, feces, and infections of the mouth, soft tissue, respiratory tract, urogenital tract, and intestinal tract. It is pathogenic, but usually in association with other kinds of organisms.
Fusobacterium
Microbial Sensitivity Tests
Abscess
Anaerobiosis
Metronidazole
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
Drug Resistance, Microbial
Imipenem
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Cefotetan
Prevotella
A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods. Organisms of this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings in 1990 indicated the need to separate them from other Bacteroides species, and hence, this new genus was established.
Peptostreptococcus
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Abdominal Abscess
beta-Lactamases
Gram-Negative Anaerobic Bacteria
Feces
Cephamycins
Moxalactam
Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Thienamycins
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
Porphyromonas
A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods or coccobacilli. Organisms in this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Bacteroides species, and hence, this new genus was created.
Conjugation, Genetic
A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.
Anti-Infective Agents
Cephalosporins
Penicillanic Acid
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Bacteroidaceae
Tetracycline
Clostridium
Lactams
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
beta-Lactams
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
DNA Transposable Elements
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Cefmetazole
Cedrus
Enterotoxins
Piperacillin
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Erythromycin
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Sulbactam
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Clavulanic Acids
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
Peptococcus
Clavulanic Acid
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
Lincomycin
Colony Count, Microbial
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
The in-vitro activity of linezolid (U-100766) and tentative breakpoints. (1/843)
The in-vitro activity of linezolid, a novel oxazolidinone, was investigated in comparison with those of amoxycillin, cefuroxime, quinupristin/dalfopristin, trovafloxacin and vancomycin against 420 recent Gram-positive and anaerobic clinical isolates. Linezolid was equally active (MIC90 1 mg/L) against methicillin-susceptible and -resistant Staphylococcus aureus. It demonstrated uniform activity against streptococci and enterococci and no cross-resistance with other agents. The time-kill kinetic data demonstrated that the in-vitro activity of linezolid was predominantly bacteriostatic; slow bactericidal activity was only observed at the higher concentration with streptococci. An increase in inoculum from 10(4) to 10(6) cfu on selected strains had little effect on the MICs (MIC90 within one dilution step) of linezolid and an increase in inoculum from 10(5) to 10(7) cfu/mL had no notable effect on the in-vitro bactericidal activity. A tentative linezolid breakpoint of 2 mg/L was chosen after analysis of distribution of susceptibilities. (+info)Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro. (2/843)
BACKGROUND: Strains of Bacteroides fragilis producing a 20 kDa protein toxin (B fragilis toxin (BFT) or fragilysin) are associated with diarrhoea in animals and humans. Although in vitro results indicate that BFT damages intestinal epithelial cells in culture, the effects of BFT on native human colon are not known. AIMS: To examine the electrophysiological and morphological effects of purified BFT-2 on human colonic mucosa in vitro. METHODS: For resistance (R) measurements, colonic mucosa mounted in Ussing chambers was exposed to luminal or serosal BFT-2 (1.25-10 nM) and after four hours morphological damage was measured on haematoxylin and eosin stained sections using morphometry. F actin distribution was assessed using confocal microscopy. RESULTS: Serosal BFT-2 for four hours was four-, two-, seven-, and threefold more potent than luminal BFT-2 in decreasing resistance, increasing epithelial 3H-mannitol permeability, and damaging crypt and surface colonocytes, respectively (p<0.05). Confocal microscopy showed reduced colonocyte F actin staining intensity after exposure to BFT-2. CONCLUSIONS: BFT-2 increases human colonic permeability and damages human colonic epithelial cells in vitro. These effects may be important in the development of diarrhoea and intestinal inflammation caused by B fragilis in vivo. (+info)Microbiological and inflammatory effects of murine recombinant interleukin-10 in two models of polymicrobial peritonitis in rats. (3/843)
A protective effect of interleukin-10 (IL-10) against the development of lethal shock has been demonstrated in various animal models. In contrast, the immunosuppressant properties of this mediator have been minimally evaluated in low-mortality models of infections. The clinical, microbiological, and inflammatory effects of murine recombinant IL-10 (mrIL-10) therapy were evaluated in two models of peritonitis in rats, which differed in the degree of severity of peritoneal inflammation 3 days after inoculation of Escherichia coli and Bacteroides fragilis with or without Enterococcus faecalis. The severity of the disease remained unchanged compared to that in control animals. A dose-related decrease in the peritoneal phagocyte count was observed in the treated groups compared to the counts in control animals. The subsequent experiments were performed exclusively in the mixed gram-positive-gram negative model, which exhibits an intense and prolonged inflammatory response with similar criteria. The early effects of mrIL-10 (evaluated 6 h after inoculation), repeated injections of mrIL-10 (four doses injected from 0 to 9 h after bacterial challenge), and pretreatment (two doses injected 6 and 3 h before inoculation) were evaluated. The clinical and microbiological parameters remained unchanged in the treated animals. Decreases in the peritoneal phagocyte count and the peritoneal concentration of tumor necrosis factor were observed following repeated injections of mrIL-10. In summary, our data suggest that mrIL-10 does not worsen the manifestations of sepsis. However, these results need to be confirmed in clinical practice. (+info)Antimicrobial resistance patterns of Bacteroides fragilis group organisms in Korea. (4/843)
Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides fragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis group species were higher than those of B. fragilis for all the drugs tested. The rate of resistance to clindamycin remarkably increased and those to some beta-lactam drugs such as piperacillin and cefotaxime also increased. No isolates were found to be resistant to imipenem, metronidazole, or chloramphenicol. beta-lactam and beta-lactamase inhibitor combinations and cefoxitin were more active than the other beta-lactams. Therefore, these agents may be considered when empirical selection of antimicrobial agents is required to treat severe anaerobic infections. (+info)Diversity of bacteroides fragilis strains in their capacity to recover phages from human and animal wastes and from fecally polluted wastewater. (5/843)
Great differences in capability to detect bacteriophages from urban sewage of the area of Barcelona existed among 115 strains of Bacteroides fragilis. The capability of six of the strains to detect phages in a variety of feces and wastewater was studied. Strains HSP40 and RYC4023 detected similar numbers of phages in urban sewage and did not detect phages in animal feces. The other four strains detected phages in the feces of different animal species and in wastewater of both human and animal origin. Strain RYC2056 recovered consistently higher counts than the other strains and also detected counts ranging from 10(1) to approximately 10(3) phages per ml in urban sewage from different geographical areas. This strain detected bacteriophages in animal feces even though their relative concentration with respect to the other fecal indicators was significantly lower in wastewater polluted with animal feces than in urban sewage. (+info)Bacteroides fragilis transfer factor Tn5520: the smallest bacterial mobilizable transposon containing single integrase and mobilization genes that function in Escherichia coli. (6/843)
Many bacterial genera, including Bacteroides spp., harbor mobilizable transposons, a class of transfer factors that carry genes for conjugal DNA transfer and, in some cases, antibiotic resistance. Mobilizable transposons are capable of inserting into and mobilizing other, nontransferable plasmids and are implicated in the dissemination of antibiotic resistance. This paper presents the isolation and characterization of Tn5520, a new mobilizable transposon from Bacteroides fragilis LV23. At 4,692 bp, it is the smallest mobilizable transposon reported from any bacterial genus. Tn5520 was captured from B. fragilis LV23 by using the transfer-deficient shuttle vector pGAT400DeltaBglII. The termini of Tn5520 contain a 22-bp imperfect inverted repeat, and transposition does not result in a target site repeat. Tn5520 also demonstrates insertion site sequence preferences characterized by A-T-rich nucleotide sequences. Tn5520 has been sequenced in its entirety, and two large open reading frames whose predicted protein products exhibit strong sequence similarity to recombinase-integrase enzymes and mobilization proteins, respectively, have been identified. The transfer, mobilization, and transposition properties of Tn5520 have been studied, revealing that Tn5520 mobilizes plasmids in both B. fragilis and Escherichia coli at high frequency and also transposes in E. coli. (+info)TNF-binding protein ameliorates inhibition of skeletal muscle protein synthesis during sepsis. (7/843)
We examined the effects of TNF-binding protein (TNFBP) on regulatory mechanisms of muscle protein synthesis during sepsis in four groups of rats: Control; Control+TNFBP; Septic; and Septic+TNFBP. Saline (1. 0 ml) or TNFBP (1 mg/kg, 1.0 ml) was injected daily starting 4 h before the induction of sepsis. The effect of TNFBP on gastrocnemius weight, protein content, and the rate of protein synthesis was examined 5 days later. Sepsis reduced the rate of protein synthesis by 35% relative to controls by depressing translational efficiency. Decreases in protein synthesis were accompanied by similar reductions in protein content and muscle weight. Treatment of septic animals with TNFBP for 5 days prevented the sepsis-induced inhibition of protein synthesis and restored translational efficiency to control values. TNFBP treatment of Control rats for 5 days was without effect on muscle protein content or protein synthesis. We also assessed potential mechanisms regulating translational efficiency. The phosphorylation state of p70(S6) kinase was not altered by sepsis. Sepsis reduced the gastrocnemius content of eukaryotic initiation factor 2Bepsilon (eIF2Bepsilon), but not eIF2alpha. The decrease in eIF2Bepsilon content was prevented by treatment of septic rats with TNFBP. TNFBP ameliorates the sepsis-induced changes in protein metabolism in gastrocnemius, indicating a role for TNF in the septic process. The data suggest that TNF may impair muscle protein synthesis by reducing expression of specific initiation factors during sepsis. (+info)Structural consequences of the active site substitution Cys181 ==> Ser in metallo-beta-lactamase from Bacteroides fragilis. (8/843)
The metallo-beta-lactamases require divalent cations such as zinc or cadmium for hydrolyzing the amide bond of beta-lactam antibiotics. The crystal structure of the Zn2+ -bound enzyme from Bacteroides fragilis contains a binuclear zinc center in the active site. A hydroxide, coordinated to both zinc atoms, is proposed as the moiety that mounts the nucleophilic attack on the carbonyl carbon atom of the beta-lactam bond of the substrate. It was previously reported that the replacement of the active site Cys181 by a serine residue severely impaired catalysis while atomic absorption measurements indicated that binding of the two zinc ions remained intact. Contradicting data emerge from recent mass spectrometry results, which show that only a single zinc ion binds to the C181S metallo-beta-lactamase. In the current study, the C181S mutant enzyme was examined at the atomic level by determining the crystal structure at 2.6 A resolution. The overall structure of the mutant enzyme is the same as that of the wild-type enzyme. At the mutation site, the side chain of Ser181 occupies the same position as that of the side chain of Cys181 in the wild-type protein. One zinc ion, Zn1, is present in the crystal structure; however, the site of the second zinc ion, Zn2 is unoccupied. A water molecule is associated with Zn1, reminiscent of the hydroxide seen in the structure of the wild-type enzyme but farther from the metal. The position of the water molecule is off the plane of the carboxylate group of Asp103; therefore, the water molecule may be less nucleophilic than a water molecule which is coplanar with the carboxylate group. (+info)Molecular evolution of the pathogenicity island of enterotoxigenic Bacteroides fragilis strains<...
Simultaneous detection of Bacteroides fragilis group species by leuB -directed PCR - Arimochi, Hideki - Authors - Tokushima...
A single chromosome assembly of Bacteroides fragilis strain BE1 from Illumina and MinION nanopore sequencing data<...
Bacteroides fragilis Enterotoxin Gene Sequences in Patients with Inflammatory Bowel Disease - Volume 6, Number 2-April 2000 -...
National Survey on the Susceptibility of Bacteroides fragilis Group: Report and Analysis of Trends for 1997-2000 : Clinical...
Examination of cfiA-mediated carbapenem resistance in Bacteroides fragilis strains from a European antibiotic susceptibility...
GigaDB Dataset - DOI 10.5524/100177 - Supporting data for A single chromosome assembly of Bacteroides fragilis strain BE1 from...
Cellular immunity to Bacteroides fragilis capsular polysaccharide. | JEM
Bacteroides fragilis enterotoxin gene sequences in patients with inflammatory bowel disease
A recent fixation of cfiA genes in a monophyletic cluster of Bacteroides fragilis is correlated with the presence of multiple...
EC 2.4.1.281
The dissemination of C10 cysteine protease genes in Bacteroides fragilis by mobile genetic elements | BMC Microbiology | Full...
leuS - Leucine--tRNA ligase - Bacteroides fragilis (strain YCH46) - leuS gene & protein
Stat3 activation in murine colitis induced by enterotoxigenic Bacteroides fragilis
Structures of Bacteroides fragilis uridine 5-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (BfLpxA).
A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant...
The dissemination of C10 cysteine protease genes in Bacteroides fragilis by mobile genetic elements | BMC Microbiology | Full...
Occurrence of Bacteroides fragilisEnterotoxin Gene-Carrying Strains in Germany and the United States | Journal of Clinical...
Cloning and expression of the Bacteroides fragilis TAL2480 neuraminidase gene, nanH, in Escherichia coli. | Journal of...
Bacteroides fragilis (Veillon and Zuber) Castellani and Chalmers ATCC
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Biological activity of Bacteroides fragilis]. - MyScienceWork
Alterations in opsonophagocytic killing by neutrophils of Bacteroides fragilis associated with animal and laboratory passage:...
The intestinal microbiome of fish under starvation | BMC Genomics | Full Text
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone. | Antimicrobial Agents and...
Friend and Foe Alike | Science
Antibiotic resistance of anaerobic bacteria of the Bacteroides fragilis
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Comparison of the Giemsa C-banded karyotypes of the three subspecies of Psathyrostachys fragilis, subspp. villosus (2x),...
Bacillus fragilis synonyms, Bacillus fragilis antonyms - FreeThesaurus.com
Nitrogen metabolizing enzymes from Bacteroides fragilis (2 projects) - SBRU
Evaluation of peritoneal reinfection after fecal peritonitis
Twenty-eight divergent polysaccharide loci specifying within and amongst strain capsule diversity in three strains of...
Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes |...
BF9343 0029 - Putative beta-galactosidase - Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343) -...
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Dynamics of the metallo-beta-lactamase from Bacteroides fragil...
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Isolation of Metronidazole-Resistant Bacteroides fragilis Carrying the nimA Nitroreductase Gene from a Patient in Washington...
The design and analysis of unique DNA primer sets and probes to identify and distinguish the bacillus cereus group species:...
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Construction of a genomic library of the lactose utilising yeast Kluyveromyces marxianus var. fragilis for transformation into...
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An anaerobic bacterium, Bacteroides thetaiotaomicron, uses a consortium of enzymes to scavenge hydrogen peroxide<...
Frontiers | The Glycolytic Versatility of Bacteroides uniformis CECT 7771 and Its Genome Response to Oligo and Polysaccharides ...
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The use of parenteral clindamycin in the treatment of obstetric gynecologic patients with severe infections. A comparison of a...
Bacteroides - Wikipedia, a enciclopedia libre
Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans | Biochemical Journal
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Relative abundance of Bacteroides spp. in stools and wastewaters as determined by hierarchical oligonucleotide primer extension...
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Biological classification - Simple English Wikipedia, the free encyclopedia
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Bacteroides fragilis
Bacteroides references in Baron's Medical Microbiology (online at the NCBI bookshelf). Type strain of Bacteroides fragilis at ... Bacteroides fragilis is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium. It is part of the normal microbiota ... Bacteroides fragilis resides in the human gastrointestinal tract and is essential to healthy gastrointestinal function such as ... Bacteroides fragilis is involved in 90% of anaerobic peritoneal infections. It also causes bacteremia associated with intra- ...
Nanaerobe
Bacteroides fragilis). Like other anaerobes, these organisms do not require oxygen for growth. This growth benefit requires the ...
Peritonitis
Bacteroides fragilis). Fecal peritonitis results from the presence of faeces in the peritoneal cavity. It can result from ...
Cefpirome
Bacteroides fragilis, enterococci, Pseudomonas spp. and staphylococci are resistant to cefpirome sulfate, and some Haemophilus ...
Phosphonopyruvate decarboxylase
Zhang G, Dai J, Lu Z, Dunaway-Mariano D (2003). "The phosphonopyruvate decarboxylase from Bacteroides fragilis". J. Biol. Chem ...
Vaginal flora
Lactobacilli have been shown to inhibit in vitro growth of pathogenic microorganisms, e.g. Bacteroides fragilis, Escherichia ... and Bacteroides spp., Fusobacterium spp., Gardnerella vaginalis, Mobiluncus, Prevotella spp., and Gram-negative enteric ...
Fragilysin
Obiso RJ, Lyerly DM, Van Tassell RL, Wilkins TD (October 1995). "Proteolytic activity of the Bacteroides fragilis enterotoxin ... Fragilysin (EC 3.4.24.74, Bacteroides fragilis (entero)toxin) is an enzyme. This enzyme catalyses the following chemical ... Donelli G, Fabbri A, Fiorentini C (January 1996). "Bacteroides fragilis enterotoxin induces cytoskeletal changes and surface ... "The enterotoxin of Bacteroides fragilis is a metalloprotease". Infection and Immunity. 63 (1): 175-81. PMC 172975. PMID 7806355 ...
Tigecycline
Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Clostridium perfringens, and ... and Bacteroides fragilis. Tigecycline is indicated for treatment of complicated intra-abdominal infections caused by; ...
Cefpodoxime
Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as ...
Bacteroides
One of the most important clinically is Bacteroides fragilis. Bacteroides melaninogenicus has recently been reclassified and ... Bacteroides species also benefit their host by excluding potential pathogens from colonizing the gut. Some species (B. fragilis ... Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, ... Bacteroides infections in E Medicine Bacteroides in detail. Portal: Biology (All articles with dead external links, Articles ...
Alpha-galactosidase
The current B-zyme used comes from Bacteroides fragilis. The idea of maintaining a blood supply at healthcare facilities with ...
Pharmacomicrobiomics
2010). "Bacteroides fragilis RecA protein overexpression causes resistance to metronidazole". Res Microbiol. 161 (5): 346-354. ...
7alpha-hydroxysteroid dehydrogenase
... and NADP-dependent 7alpha-hydroxysteroid dehydrogenases from bacteroides fragilis". Biochimica et Biophysica Acta (BBA) - ...
Cefotaxime
As listed, it has modest activity against the anaerobic Bacteroides fragilis. The following represents MIC susceptibility data ... Bacteroides spp. Fusobacterium spp. Notable organisms against which cefotaxime is not active include Pseudomonas and ...
Carbapenem
... s generally exhibit good activity against anaerobes such as Bacteroides fragilis. Like other beta lactam antibiotics ...
Host-cell reactivation
Jones DT, Robb FT, Woods DR (December 1980). "Effect of oxygen on Bacteroides fragilis survival after far-ultraviolet ...
Choloylglycine hydrolase
"Purification and characterization of bile salt hydrolase from Bacteroides fragilis subsp. fragilis". Biochim. Biophys. Acta. ...
List of restriction enzyme cutting sites: Bd-Bp
Reinecke SN, Morgan RD (March 1991). "BfaI, a new MaeI isoschizomer from Bacteroides fragilis, recognizes the sequence 5' C ... Azeddoug H, Reysset G, Sebald M (August 1992). "Characterization of restriction endonuclease BfrBI from Bacteroides fragilis ...
Bacteroidales-1 RNA motif
Bayley DP, Rocha ER, Smith CJ (December 2000). "Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter ... Bacteroidales-1 RNA motif has been reported as a 6S RNA homologue by a report of Bacteroides thetaiotaomicron transcriptome map ... "A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides ...
Metallo-beta-lactamase protein fold
This belief was soon debunked when the structure of Bacteroides fragilis ZBL, CcrA, was published, showing an additional Zn(II ... "Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis". Structure. 4 (7): 823-36. doi: ...
Imipenem
Bacteroides fragilis, and Enterococcus faecalis have developed resistance to imipenem to varying degrees. Not many species are ... Acinetobacter anitratus, Acinetobacter calcoaceticus, Actinomyces odontolyticus, Aeromonas hydrophila, Bacteroides distasonis, ... Bacteroides uniformis, and Clostridium perfringens are generally susceptible to imipenem, while Acinetobacter baumannii, some ...
List of sequenced bacterial genomes
2004). "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation". PNAS. ... 2005). "Extensive DNA inversions in the B. fragilis genome control variable gene expression" (PDF). Science. 307 (5714): 1463-5 ... 2003). "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis". Science. 299 (5615): 2074-6. Bibcode:2003Sci... ...
Anaerobic infection
Bacteroides fragilis group is rarely recovered in these infections compared to intra-abdominal infection. Actinomyces spp. and ... Bacteroides fragilis).Clostridium perfringens can cause of brain abscesses and meningitis following intracranial surgery or ... Anaerobes (mostly B. fragilis group, and rarely C. perfringens) can be recovered in complicated infections associated with ... are especially common in bite and skull bone infections, whereas members of the B. fragilis group are often found in vascular ...
Infection
An example of this is appendicitis, which is caused by Bacteroides fragilis and Escherichia coli. The second is an iatrogenic ...
Lipopolysaccharide binding protein
Erridge, C; Pridmore, A; Eley, A; Stewart, J; Poxton, IR (2004). "Lipopolysaccharides of Bacteroides fragilis, Chlamydia ...
Glutamine synthetase
Class III enzymes (GSIII) have, currently, only been found in Bacteroides fragilis and in Butyrivibrio fibrisolvens. It is a ...
Taurolidine
Anaerobes (MIC 0.03-0.3 mg/mL): Bacteroides species (including B. fragilis), Fusobacteriota, Clostridium species, ...
Bacteroides thetaiotaomicron
This genomic feature is shared with another member of the genus with a similar lifestyle, Bacteroides fragilis. The genome is ... Bacteroides thetaiotaomicron is one of the most common components of the human gut flora. In a long-term study of Bacteroides ... Bacteroides thetaiotaomicron (formerly Bacillus thetaiotaomicron) is a species of bacterium of the genus Bacteroides. It is a ... behind Bacteroides fragilis. B. thetaiotaomicron is considered commensal or symbiotic. However, it is also an opportunistic ...
Tubo-ovarian abscess
Bacteroides fragilis, other Bacteroides species, Peptostreptococcus, Peptococcus, and aerobic streptococci. Long term IUD use ...
Fumarate reductase (quinol)
... and Bacteroides fragilis. Each of these organisms has slightly different gene regulation and function in addition to different ... "Fumarate reductase is a major contributor to the generation of reactive oxygen species in the anaerobe Bacteroides fragilis". ...
Innate immune system
Bacteroides species are normally mutualistic bacteria, making up a substantial portion of the mammalian gastrointestinal flora ... Species such as B. fragilis are opportunistic pathogens, causing infections of the peritoneal cavity. They inhibit phagocytosis ...
Peptostreptococcus
In this case they are mixed with organisms of intestinal origin such as E coli, bacteroides fragilis group, and clostridium ...
Bacteroides caccae
"Antimicrobial susceptibility of relatively infrequent isolates of the Bacteroides fragilis group: Bacteroides uniformis, ... Bacteroides caccae is a saccharolytic gram-negative bacterium from the genus Bacteroides. They are obligate anaerobes first ... nov., Bacteroides merdae sp. nov., and Bacteroides stercoris sp. nov. Isolated from Human Feces" (PDF). International Journal ... Bacteroides caccae". LPSN.DSMZ.de. "Bacteroides caccae". www.ncbi.nlm.nih.gov. National Center for Biotechnology Information, U ...
Sultamicillin
Gynecological infections - Caused by beta-lactamase producing strains of E. coli and Bacteroides sp. (including B. fragilis). ...
Cefotetan
Escherichia coli: 0.06 µg/mL Bacteroides fragilis: ≤0.06 µg/mL - 512 µg/mL Clostridium perfringens: 1 µg/mL - 4 µg/mL Stork CM ... Notable species include Bacteroides, Streptococcus, and Escherichia. The following represents MIC susceptibility data for a few ...
Mezlocillin
Bacteroides spp., including B. fragilis Enterobacter spp. Escherichia coli Haemophilus influenzae Klebsiella species Morganella ...
Lemierre's syndrome
... which include Bacteroides fragilis and Bacteroides melaninogenicus, Peptostreptococcus spp., Streptococcus microaerophile, ...
Necrotizing pneumonia
... anaerobes like Fusobacterium nucleatum and Bacteroides fragilis; fungi like Aspergillus sp. and Histoplasma capsulatum; viruses ...
Dentures
However, dentures made from acrylic can be fragile and fracture easily if the patient has trouble adapting neuromuscular ... Fusobacterium and Bacteroides species. Acrylic resin is more susceptible for fungal colonisation, adherence and proliferation. ...
Microbial symbiosis and immunity
For example, the human symbiont Bacteroides fragilis produces polysaccharide A (PSA), which binds to toll-like receptor 2 (TLR- ... Bacteroides thetaiotaomicron, a bacterial species in the ileum and colon, stimulates the gene encoding fucose, Fut2, in ... These data suggest that PSA secreted by B. fragilis suppresses the inflammatory process during colitis by leading to increased ... However, some bacteria, including the human symbiont B. fragilis, may prevent colitis by producing polysaccharide A (PSA). PSA ...
Ertapenem
Bacteroides distasonis Bacteroides fragilis Bacteroides ovatus Bacteroides thetaiotaomicron Bacteroides uniformis Bacteria that ...
Cefotiam
Bacteroides fragilis: - 16 - >128 μg/ml Clostridium difficile: >128 μg/ml Staphylococcus aureus: 0.25 - 32 μg/ml Side effects ...
Sarkis Mazmanian
The New York Times noted Symbiotix as 'developing a complex sugar called PSA, which is associated with Bacteroides fragilis, ... Working in Dennis Kasper's lab, he showed in 2005 that a particular bacterial species, Bacteroides fragilis, from the human ... which is associated with Bacteroides fragilis, into treatments for intestinal disease and multiple sclerosis.) In his view, the ... These discoveries include the demonstration that B. fragilis can treat experimental inflammatory bowel disease by inducing the ...
Bacteroidota
Bacteroides fragilis was the first Bacteroides species isolated in 1898 as a human pathogen linked to appendicitis among other ... Some "Bacteroides spp. have a potential to utilize urea as a nitrogen source. Other important functions of Bacteroides spp. ... as non-digestible oligosaccharides in mother milk support the growth of both Bacteroides and Bifidobacterium spp. Bacteroides ... Bacteroides spp. in contrast to Prevotella spp. were recently found to be enriched in the metagenomes of subjects with low gene ...
Clindamycin
... although resistance is increasing in Bacteroides fragilis. Most aerobic Gram-negative bacteria (such as Pseudomonas, Legionella ... Anaerobic, Gram-negative rod-shaped bacteria, including some Bacteroides, Fusobacterium, and Prevotella, ...
List of International Organization for Standardization standards, 10000-11999
Enumeration of bacteriophages infecting Bacteroides fragilis ISO 10711:2012 Intelligent Transport Systems - Interface Protocol ...
Mouth ulcer
... vesicles and bullae which form on the mucous membranes of the oral cavity tend to be fragile and quickly break down to leave ... and Bacteroides species can prolong the ulcerative process. Fungal causes include Coccidioides immitis (valley fever), ... making the lining more fragile and easily breached.: 7 Stomatitis is a general term meaning inflammation within the mouth, and ...
Multidrug-Resistant Bacteroides fragilis - Seattle, Washington, 2013
... The Bacteroides fragilis group consists of species of ... Species identification was confirmed as Bacteroides fragilis ssp. fragilis by biochemical testing, mass spectrometry, and ... Multidrug resistant Bacteroides fragilis recovered from blood and severe leg wounds caused by an improvised explosive device ( ... Bacteroides fragilis are anaerobic bacteria found in the human gastrointestinal tract and often cause intra-abdominal ...
RCSB PDB - 3FKF: thiol-disulfide oxidoreductase from Bacteroides fragilis NCTC 9343
Bacteroides fragilis NCTC 9343. Mutation(s): 0 Gene Names: BF9343_4170, NCTC9343_01554. EC: 1.8.4.7. ... Find proteins for Q5L7K1 (Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)) ... thiol-disulfide oxidoreductase from Bacteroides fragilis NCTC 9343. Duke, N.E.C., Freeman, L., Tesar, C., Joachimiak, A.. To be ... thiol-disulfide oxidoreductase from Bacteroides fragilis NCTC 9343. *PDB DOI: 10.2210/pdb3FKF/pdb ...
ReP USP - Detalhe do registro: Evaluation of the pathogenicity of the bacteroides fragilis toxin gene subtypes in gnotobiotic...
Evaluation of the pathogenicity of the bacteroides fragilis toxin gene subtypes in gnotobiotic mice (2006). *Authors: *Nakano, ... Evaluation of the pathogenicity of the bacteroides fragilis toxin gene subtypes in gnotobiotic mice. Current Microbiology, v. ... Evaluation of the pathogenicity of the bacteroides fragilis toxin gene subtypes in gnotobiotic mice. Current Microbiology. 2006 ... Evaluation of the pathogenicity of the bacteroides fragilis toxin gene subtypes in gnotobiotic mice. Current Microbiology. 2006 ...
IMSEAR at SEARO: Susceptibility to current antimicrobial agents of Bacteroides fragilis.
Susceptibility to current antimicrobial agents of Bacteroides fragilis.. Autor : Dhamabutra, N. Sripayak, B. Chongthalung, A. ... Agar dilution technique susceptibility test of isolated Bacteroides fragilis from the normal healthy womens and infected ... Susceptibility to current antimicrobial agents of Bacteroides fragilis. Journal of the Medical Association of Thailand. 1989 ...
JoF | Free Full-Text | Candida spp./Bacteria Mixed Biofilms
Interactions between the gut-associated Bacteroides fragilis NCTC 9343, Bacteroides vulgatus ATCC 8482, and C. albicans were ... The Bacteroides fragilis group and Clostridium spp. are also isolated from patients with abdominal, gastrointestinal, or ... The cell-free supernatant of 24-h-old C. albicans CAB 392 monocultures was able to increase the number of Bacteroides and the ... Remarkably, the supplementation of Bacteroides monocultures with dead C. albicans CAB 392 cells (with outer cell wall mannan ...
Zinc in PDB 3hxs: Crystal Structure of Bacteroides Fragilis Trxp
Crystal Structure of Bacteroides Fragilis Trxp. Protein crystallography data. The structure of Crystal Structure of Bacteroides ... Zinc binding site 1 out of 2 in the Crystal Structure of Bacteroides Fragilis Trxp. Mono view Stereo pair view ... Zinc binding site 2 out of 2 in the Crystal Structure of Bacteroides Fragilis Trxp. Mono view Stereo pair view ... A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Bacteroides Fragilis Trxp ...
Septic Shock: Practice Essentials, Background, Pathophysiology
Septic Shock: Practice Essentials, Background, Pathophysiology
Table - Automated Biosurveillance Data from England and Wales, 1991-2011 - Volume 19, Number 1-January 2013 - Emerging...
The molecular characterisation of the recA locus in the opportunistic pathogen Bacteroides fragilis
Nicholson, S. A. (2012). The molecular characterisation of the recA locus in the opportunistic pathogen Bacteroides fragilis. ( ... "The molecular characterisation of the recA locus in the opportunistic pathogen Bacteroides fragilis." Thesis., University of ... Bacteroides fragilis is a human gut commensal and an opportunistic pathogen causing anaerobic abscesses and bacteraemias which ... The molecular characterisation of the recA locus in the opportunistic pathogen Bacteroides fragilis. Login ...
Epigenetic Changes Induced by |i|Bacteroides fragilis|/i| Toxin. | Infect Immun;87(6)2019 06. | MEDLINE | Biblioteca...
Toxinas Bacterianas/toxicidade Infecções por Bacteroides/genética Infecções por Bacteroides/microbiologia Bacteroides fragilis/ ... Infecções por Bacteroides/metabolismo Bacteroides fragilis/genética Linhagem Celular Tumoral Colo/microbiologia Neoplasias ... Epigenetic Changes Induced by Bacteroides fragilis Toxin.. Allen, Jawara; Hao, Stephanie; Sears, Cynthia L; Timp, Winston. ... Enterotoxigenic Bacteroides fragilis (ETBF) is a Gram-negative, obligate anaerobe member of the gut microbial community in up ...
Toxins | Free Full-Text | Wound Infections of Snakebites from the Venomous Protobothrops mucrosquamatus and Viridovipera...
Morganella morganii, Enterococcus spp., Bacteroides fragilis, and Aeromonas hydrophila were most frequently cultured. There ... Morganella morganii, Enterococcus spp., Bacteroides fragilis, and Aeromonas hydrophila were most frequently cultured. There ... Anaerobic bacteria, such as Peptostreptococcus micros and Bacteroides fragilis, were susceptible to clindamycin and ... Bacteroides fragilis, and Aeromonas hydrophila were the most frequently cultured. Patients with a BITE score of 5 were at high ...
Nationwide study of the susceptibility of the Bacteroides fragilis group in the United States. | [email protected]
Nationwide study of the susceptibility of the Bacteroides fragilis group in the United States. ... Nationwide study of the susceptibility of the Bacteroides fragilis group in the United States. Journal Article (Journal Article ... A nationwide susceptibility survey of the Bacteroides fragilis group was continued at New England Medical Center in 1983. A ... These data indicate the need for determining the susceptibility patterns for the B. fragilis group of organisms at each ...
2014 ICD-9-CM Diagnosis Code 482.81 : Pneumonia due to anaerobes
Antimicrobial resistance profile and Nim gene detection among Bacteroides fragilis group isolates in a university hospital in...
Bacteroides vulgatus, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides caccae, and others.[ ... The commonly isolated species was B. fragilis (73.7%), followed by Bacteroides thetaiotaomicron (8.8%), Bacteroides vulgatus ( ... Long Bone Bacteroides fragilis Osteomyelitis: a Case Report. Meletis Rozis, Aristeidis Koutsopoulos, Vasileios Marougklianis, ... Furthermore, nim gene was not detected in two of the B. fragilis isolates with Mtz MIC of 16 μg/mL.. Discussion. Bacteroides ...
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Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly...
Bacteroides fragilis, Bacteroides spp. and Prevotella spp., Bacteroides stercoris, Bacteroides zoogleoformans, Parabacteroides ... and Escherichia spp., and the relative scarcity of Bacteroides fragilis, Ruminococcus gnavus, Bacteroides spp. and Prevotella ... that are part of the Firmicutes and reduced Bacteroides fragilis that is part of the Bacteroidetes could indicate an increase ... reduced amounts of Faecalibacterium prausnitzii and Bacteroides fragilis, and increased amounts of Ruminococcus gnavus and ...
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Distribution of different species of the Bacteroides fragilis group in individuals with Japanese cedar pollinosis. Appl.Environ ... Bifidobacterium lactis and Lactobacillus F19 prevent antibiotic-associated ecological disturbances of Bacteroides fragilis in ... the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis ...
What is the most common bacteria in the gut? - Xshotpix.com
Bacteroides fragilis. How many species of bacteria are in the intestine?. However, 99% of the bacteria come from about 30 or 40 ... Bacteroides and coliform bacteria are the dominant bacteria present there, in addition to anaerobic Lactobacilli [6]. ... specifically the colon and the most prevalent bacteria are the Bacteroides, a group of Gram-negative, anaerobic, non- ...
2012 ICD-9-CM Diagnosis Code 008.46 : Intestinal infection due to other anaerobes
Ulrik Stenz Justesen - Fingerprint
- University of Southern Denmark
ClostridiumAnaerobesVulgatusThetaiotaomicronEnterococcusStrainsMelaninogenicusBacteriaSpeciesCaccaeAnaerobicStreptococcusColiAbscessesPrevotellaIsolates were identifiedStercorisPorphyromonasBacteriumETBFOrganismsToxinPolysaccharideInfectionResistantGeneLactobacillusMetronidazoleAntimicrobialMass spectrometryGroupNormalCodeImportant
Clostridium7
- Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. (lambertvetsupply.com)
- Dental infections due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. (lambertvetsupply.com)
- Osteomyelitis due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. (lambertvetsupply.com)
- Deep wounds and infections due to Clostridium perfringens and Bacteroides fragilis. (lambertvetsupply.com)
- Clostridium perfringens and Bacteroides fragilis. (lambertvetsupply.com)
- On the basis of 16S rRNA gene sequencing, these seven isolates were identified as Bacteroides stercoris (MT152636), Lactobacillus acidophilus (MT152637), Lactobacillus salivarius (MT152638), Ruminococcus bromii (MT152639), Klebsiella aerogenes (MT152640), Bacteroides fragilis (MT152909), Clostridium botulinum (MT152910). (bvsalud.org)
- Com base no sequenciamento do gene 16S rRNA, esses sete isolados foram identificados como Bacteroides stercoris (MT152636), Lactobacillus acidophilus (MT152637), Lactobacillus salivarius (MT152638), Ruminococcus bromii (MT152639), Klebsiella aerogenides (MT152640), Bacteroides fragilis (MT152909), Clostridium botulinum (MT152910). (bvsalud.org)
Anaerobes2
- Bacteroides fragilis group species are the most frequently isolated anaerobes in the clinical Microbiology laboratory. (jgid.org)
- and the most common anaerobes are Bacteroides fragilis and Peptostreptococcus species. (turkishjcrd.com)
Vulgatus2
- The commonly isolated species was B. fragilis (73.7%), followed by Bacteroides thetaiotaomicron (8.8%), Bacteroides vulgatus (8.8%), and others. (jgid.org)
- MT152626), Bacteroides faecis (MT152627), Bacteroides vulgatus (MT152628), Lactobacillus plantarum (MT152629) which were isolated from mice receiving CD/HFD. (bvsalud.org)
Thetaiotaomicron1
- We colonized germ-free mice with Bacteroides thetaiotaomicron . (cdc.gov)
Enterococcus1
- All qc strains were conform (pseudomonas aeruginosa atcc 27853, escherichia coli atcc 25922, staphylococcus aureus atcc 29213, enterococcus faecalis atcc 29212, bacteroides fragilis atcc 25285, streptococcus pneumoniae atcc 49619, haemophilus influenzae atcc 49766) and the neqas strain gave mic equal to 0. (fda.gov)
Strains6
- B. fragilis strains, especially in the United States, are virtually always susceptible to metronidazole, carbapenems, and beta-lactam antibiotics ( 1 ). (cdc.gov)
- Although isolated cases of resistance to single agents have been reported, multidrug-resistant (MDR) B. fragilis strains are exceptionally rare ( 1,2 ). (cdc.gov)
- [6] However, the increasing frequency of B. fragilis group strains resistant to Mtz has resulted in adverse clinical outcomes. (jgid.org)
- Penicillin G and its oral congeners (eg, penicillin V) are active against both aerobic and anaerobic gram-positive bacteria and, with a few exceptions ( Haemophilus and Neisseria spp and strains of Bacteroides other than B fragilis ), are inactive against gram-negative organisms at usual concentrations. (merckvetmanual.com)
- Presence of diaminopimelic acid in propionate negative Bacteroides species and in some butyric acid-producing strains. (microbiologyresearch.org)
- Bacterial strains including Bacteroides gallinarum (MT152630), Ruminococcus bromii (MT152631), Lactobacillus acidophilus (MT152632), Parabacteroides gordonii (MT152633), Prevotella copri (MT152634) and Lactobacillus gasseri (MT152635) were isolated from mice treated with GM+modified diet (HFD/CD) compared to strains Akkermansia muciniphila (MT152625), Bacteriodes sp. (bvsalud.org)
Melaninogenicus1
- The classification of Bacteroides melaninogenicus and related species. (microbiologyresearch.org)
Bacteria4
- The Bacteroides fragilis group consists of species of obligate anaerobic bacteria that inhabit the human gut. (cdc.gov)
- In the ileocaecal valve, Bacteroides and coliform bacteria are the dominant bacteria present there, in addition to anaerobic Lactobacilli [6]. (xshotpix.com)
- 11) The greatest number of bacteria are found in the lower intestinal tract, specifically the colon and the most prevalent bacteria are the Bacteroides, a group of Gram-negative, anaerobic, non-sporeforming bacteria. (xshotpix.com)
- Clausen, who works as a paid consultant to ZymeQuest, sifted through 2,500 bacteria and fungi before pinpointing a gut bacterium, Bacteroides fragilis, which produces an enzyme capable of pruning the B antigen, and a second bug, Elizabethkingia meningosepticum, which yields enzymes that are effective against the A antigen. (popsci.com)
Species5
- [5] The antimicrobial resistance rates among the B. fragilis group have been reported to vary among the various species. (jgid.org)
- The asaccharolytic, pigmented Bacteroides, Bacteroides asaccharolyticus, Bacteroides gingivalis , and Bacteroides endodontalis , form a group of relatively homogeneous species which differ markedly in biochemical and chemical properties from the type species of Bacteroides, Bacteroides fragilis (Castellani and Chalmers), such that they should not be retained within this genus. (microbiologyresearch.org)
- Degradation of albumin haemopexin, haptoglobin and transferrin by black-pigmented Bacteroides species. (microbiologyresearch.org)
- The isolation and identification of Bacteroides species from the normal human gingival flora. (microbiologyresearch.org)
- The most common species invading the small intestine in SIBOS are Escherichia coli and Bacteroides . (naturalmedicinejournal.com)
Caccae1
- Bacteroides caccae sp. (microbiologyresearch.org)
Anaerobic8
- Bacteroides fragilis is a human gut commensal and an opportunistic pathogen causing anaerobic abscesses and bacteraemias which are treated with the drug, metronidazole, a DNA damaging agent. (uct.ac.za)
- The findings of this research have resulted in the following hypothesis: The recA operon of B. fragilis acts during host invasion to contribute to the maintenance of DNA integrity and the anaerobic cellular environment until the oxyR regulated system and the pathogenicity genes are activated. (uct.ac.za)
- Members of Bacteroides fragilis group are the most frequently isolated anaerobic pathogens in the clinical laboratory from diverse infection sites. (jgid.org)
- The objective of this study was to characterize B. fragilis isolates from various clinical specimens, to analyze their susceptibility profile toward most common anti-anaerobic antimicrobials, and to study the frequency of nim gene determining resistance to nitroimidazoles. (jgid.org)
- Resistance to the most commonly used empirical anti-anaerobic drugs including Mtz was noted in the isolates of B. fragilis group. (jgid.org)
- [3] , [4] The antimicrobial resistance, particularly within the B. fragilis group among the anaerobic bacterial pathogens has been reported from across the globe with reports of resistance to metronidazole (Mtz), β-lactam-β-lactamase inhibitor combinations, and carbapenems. (jgid.org)
- [ 1 ] group and other anaerobic gram-negative bacilli (AGNB) that were previously included in the Bacteroides genus but are now included in the Prevotella and Porphyromonas genera. (medscape.com)
- The most common infectious anaerobic agents are Gram-negative bacilli belonging to the Bacteroides / Parabacteroides , which under normal conditions constitute the natural human microflora. (microbiology.pl)
Streptococcus1
- Those microorganisms that are potential indicators of contamination in a dental environment include Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, Streptococcus mitis, Streptococcus salivarius, Corynebacterium diphtheriae, Bacteroides fragilis and Peptoestreptococus. (bvsalud.org)
Coli2
- Heterologous complementation and protein expression of BCP in E. coli, with subsequent biochemical assay, showed that the B. fragilis bcp gene encoded a functional bacterioferritin co-migratory protein (BCP), which is a small thiol-specific protein with antioxidant properties. (uct.ac.za)
- The other gene codes for resistance in tetracycline and is expressed in aerobically grpwn E. coli, but not in anaerobically grpwn E. coli or in bacteroides. (ipl.org)
Abscesses1
- In May 2013, an MDR B. fragilis strain was isolated from the bloodstream and intra-abdominal abscesses of a patient who had recently received health care in India. (cdc.gov)
Prevotella1
- Prevotella bivia and Prevotella disiens (previously called Bacteroides ) are important in obstetric and gynecologic infections. (medscape.com)
Isolates were identified1
- Both blood culture and abdominal fluid culture isolates were identified as B. fragilis . (cdc.gov)
Stercoris1
- nov., and Bacteroides stercoris sp. (microbiologyresearch.org)
Porphyromonas1
- Therefore, we propose that Bacteroides asaccharolyticus (Holdeman and Moore) Finegold and Barnes, Bacteroides gingivalis Coykendall, Kaczmarek and Slots, and Bacteroides endodontalis van Steenbergen, van Winkelhoff, Mayrand, Grenier and de Graaff be reclassified in a new genus, Porphyromonas , as Porphyromonas asaccharolytica comb. (microbiologyresearch.org)
Bacterium1
- Researchers say the findings are the first to suggest that an envelope molecule from a bacterium called Bacteroides fragilis (B. fragilis) might be useful against viral inflammatory diseases. (neurosciencenews.com)
ETBF3
- Enterotoxigenic Bacteroides fragilis (ETBF) is a Gram-negative, obligate anaerobe member of the gut microbial community in up to 40% of healthy individuals. (bvsalud.org)
- tumor formation is dependent on ETBF-secreted Bacteroides fragilis toxin (BFT). (bvsalud.org)
- Enterotoxigenic B fragilis (ETBF) is also a potential cause of diarrhea. (medscape.com)
Organisms1
- These data indicate the need for determining the susceptibility patterns for the B. fragilis group of organisms at each hospital. (duke.edu)
Toxin1
- Epigenetic Changes Induced by Bacteroides fragilis Toxin. (bvsalud.org)
Polysaccharide3
- Total synthesis of the bacteroides fragilis zwitterionic polysaccharide A1 repeating unit. (mpg.de)
- De novo synthesis of a 2-acetamido-4-amino-2,4,6-trideoxy-D-galactose (AAT) building block for the preparation of a Bacteroides fragilis A1 polysaccharide fragment. (mpg.de)
- B fragilis' polysaccharide A enhances homeostatic immune function both in the gut and systemically and balances T-cell subset population size and function. (medscape.com)
Infection1
- This mouse study shows that B. fragilis PSA can temper the immune system so that infection does not result in an uncontrolled, potentially fatal inflammatory response in the brain," Cantin said. (neurosciencenews.com)
Resistant1
- However, in addition to the B fragilis group, which is resistant to penicillin, other AGNB show increased resistance. (medscape.com)
Gene2
- The aim of this thesis was to characterise the B. fragilis recA gene cluster with respect to its genomic context and the transcriptional regulation of the genes in response to metronidazole and oxygen stress. (uct.ac.za)
- RT-PCR of B. fragilis cDNA showed that the recA gene was co-transcribed as an operon together with two upstream genes. (uct.ac.za)
Lactobacillus1
- When subjected to batch fermentations by individual cultures of Lactobacillus casei , Bifidobacterium bifidum , and Bacteroides fragilis , the hemicellulosic hydrolysates elicited varied responses. (usda.gov)
Metronidazole2
- The B fragilis group is almost uniformly susceptible to metronidazole, carbapenems, chloramphenicol, and combinations of a penicillin and beta-lactamase inhibitors. (medscape.com)
- The functional characterisation of the RecA protein from B. fragilis showed that it was important for survival after exposure to nitrogen (metronidazole) and oxygen (hydrogen peroxide) radicals. (uct.ac.za)
Antimicrobial3
- IMSEAR at SEARO: Susceptibility to current antimicrobial agents of Bacteroides fragilis. (who.int)
- Dhamabutra N, Sripayak B, Chongthalung A, Vichivanives P. Susceptibility to current antimicrobial agents of Bacteroides fragilis. (who.int)
- Agar dilution technique susceptibility test of isolated Bacteroides fragilis from the normal healthy women's and infected gynecological patients' cervical areas were studied with current antimicrobial agents. (who.int)
Mass spectrometry1
- Isolates of B. fragilis group were identified and speciated by mass spectrometry. (jgid.org)
Group4
- Nationwide study of the susceptibility of the Bacteroides fragilis group in the United States. (duke.edu)
- A nationwide susceptibility survey of the Bacteroides fragilis group was continued at New England Medical Center in 1983. (duke.edu)
- A total of 57 isolates of B. fragilis group were studied. (jgid.org)
- Multiple resistance mechanisms to Mtz have been reported in the B. fragilis group. (jgid.org)
Normal1
- Both insertional and deletion mutation methods were attempted but neither produced viable mutants in either of the upstream genes, suggesting that they may be critical for the survival of B. fragilis under normal growth conditions. (uct.ac.za)
Code1
- The binding sites of Zinc atom in the Crystal Structure of Bacteroides Fragilis Trxp (pdb code 3hxs ). (atomistry.com)
Important1
- Bacteroides spp possess important immunomodulatory effects and the body's energy balance. (medscape.com)