A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Membrane Transport Proteins
Kidd Blood-Group System
Access to Information
Journal Impact Factor
Peer Review, Research
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
Abstracting and Indexing as Topic
The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Nucleic Acid Conformation
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Mitochondrial Proton-Translocating ATPases
ATP Synthetase Complexes
Bacterial Proton-Translocating ATPases
Membrane-bound proton-translocating ATPases that serve two important physiological functions in bacteria. One function is to generate ADENOSINE TRIPHOSPHATE by utilizing the energy provided by an electrochemical gradient of protons across the cellular membrane. A second function is to counteract a loss of the transmembrane ion gradient by pumping protons at the expense of adenosine triphosphate hydrolysis.
Dissertations, Academic as Topic
Silicon and phosphorus linkage with iron via oxygen in the amorphous matrix of Gallionella ferruginea stalks. (1/2)(+info)
Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms. (2/2)(+info)
Death Star Bacterial Structures Can Be Tapped to Deliver Drugs to Targeted Cells in...
The MACs resemble similar syringe structures found on bacteriophages - viruses that infect bacteria - and with evolution, the bacteria have stolen this structure from the phages, and have put it to good use.. Phage typically attack bacteria with these structures, but instead of using it to infect other bacteria, the Pseudoalteromonas now uses it to interact with other animals, such as tubeworms, insects, and mouse cells, Shikuma said.. MACs are created when the bacteria undergo cell lysis - when the cells blow themselves up - and the bacteria that do this die afterward, so its almost like altruism because it benefits the rest of the bacterial population.. Not every bacterium in this strain produces the MACs, only about one out of 50 do so, but since we can produce trillions of these bacteria, supply will not be an issue and more of them can be engineered to produce MACs, he explained.. The findings will be published September 17th in eLife journal, and follow on the heels of a recent ...
Cross-Seeding of Misfolded Proteins: Implications for Etiology and Pathogenesis of Protein Misfolding Diseases
Although the putative biological consequences of cross-seeding have not been investigated in detail, there are several studies suggesting a molecular cross-talk between misfolded proteins in vivo. Perhaps the most emblematic study of cross-seeding in animal models is the one involving Aβ and tau proteins. The simultaneous brain accumulation of these proteins is the main hallmark of AD. Studies in animal models using various transgenic mice revealed that Aβ is able to accelerate the aggregation of tau; however, it seems that tau aggregates do not have the same effect over Aβ , . These findings suggest a possibly unidirectional cross-seeding. However, it is also possible that this outcome may be mediated by indirect processes, for example, Aβ aggregates may activate certain kinases responsible for tau phosphorylation, leading to higher misfolding and aggregation of this protein .. Another interaction that has been studied in some detail is between α-synuclein and the misfolded ...
Abiotic Surface Sensing and Biofilm-Dependent Regulation of Gene Expression in Escherichia coli | Journal of Bacteriology
In natural environments, bacteria are often found as sessile communities known as biofilms (8, 10). To date, the bacterial structures of adherence (25, 40-42, 56) and the physiological processes involved in bacterial surface colonization (15, 40, 41) are better understood than the genetic responses of bacteria adhering to a surface. By using a library oflacZ fusions and a reliable screen for identifying genes whose expression changes in biofilm versus planktonic cells, the transcription of 38% of the E. coli genes was shown to be modified during the colonization process. Several genes with altered expression in biofilms were identified. Different cellular functions were induced in attached bacteria: the OmpC porin, the high-affinity transport system of glycine betaine, colanic acid production (theE. coli class I exopolysaccharide), tripeptidase T, and synthesis of a nickel high-affinity transport system. On the other hand, the syntheses of flagella and of a putative protein of 92 amino acids ...
Abiotic Surface Sensing and Biofilm-Dependent Regulation of Gene Expression in Escherichia coli | Journal of Bacteriology
In natural environments, bacteria are often found as sessile communities known as biofilms (8, 10). To date, the bacterial structures of adherence (25, 40-42, 56) and the physiological processes involved in bacterial surface colonization (15, 40, 41) are better understood than the genetic responses of bacteria adhering to a surface. By using a library oflacZ fusions and a reliable screen for identifying genes whose expression changes in biofilm versus planktonic cells, the transcription of 38% of the E. coli genes was shown to be modified during the colonization process. Several genes with altered expression in biofilms were identified. Different cellular functions were induced in attached bacteria: the OmpC porin, the high-affinity transport system of glycine betaine, colanic acid production (theE. coli class I exopolysaccharide), tripeptidase T, and synthesis of a nickel high-affinity transport system. On the other hand, the syntheses of flagella and of a putative protein of 92 amino acids ...
BISC209: Motility - OpenWetWare
Flagella are bacterial structures that allow directed movement, called motility. Motility enables bacteria to move towards favorable environments and away from unfavorable ones and is sometimes important in the characterization and identification of bacteria. Arrangement of flagella varies among species. A flagellum may occur singly at one end, or there may be more than one flagella at one or both ends (polar). Flagella may occur in tufts, or they can be arranged all around the cell (peritrichous). Not all motile bacteria have flagella and many bacteria are non-motile. There are different ways to examine motility or motility organelles. You should begin with the motility part of the SIMS test and if that is positive, do a wet mount to confirm motility and/or do a fagella stain to see if you can see flagella ...
BSC Biology, Bangor University
This course comprises three main topics. Biopolymers - Covering aspects of the structures properties, and applications of major classes of biopolymeric material such as DNA, RNA and proteins, as well as a wide range of naturally occurring biopolymers derived from renewable resources, such as polyesters. Glycobiology - This section will introduce the role of carbohydrates in biological systems. Starting from basic concepts and terminology specific for carbohydrate chemistry, the following areas will be illuminated: properties and structures of common polysaccharides (e.g. amylose, cellulose, chitin, chitosan, peptidoglycans, pectins, dextrans, glycosaminoglycans, proteoglycans), chemical and enzymatic synthesis and degradation, complex carbohydrates (case studies: human and bacterial structures), glycoconjugates (case studies: glycoproteins, glycolipids), carbohydrates in medicine (case studies: lead structure, vaccine, inhibitor), carbohydrate recognition (case studies: lectins) in e.g. ...
Mathematical Model for Length Control by the Timing of Substrate Switching in the Type III Secretion System
Type III Secretion Systems (T3SS) are complex bacterial structures that provide gram-negative pathogens with a unique virulence mechanism whereby they grow a needle-like structure in order to inject bacterial effector proteins into the cytoplasm of a host cell. Numerous experiments have been performed to understand the structural details of this nanomachine during the past decade. Despite the concerted efforts of molecular and structural biologists, several crucial aspects of the assembly of this structure, such as the regulation of the length of the needle itself, remain unclear. In this work, we used a combination of mathematical and computational techniques to better understand length control based on the timing of substrate switching, which is a possible mechanism for how bacteria ensure that the T3SS needles are neither too short nor too long. In particular, we predicted the form of the needle length distribution based on this mechanism, and found excellent agreement with available ...
Complex bacterium writes new evolutionary story | EurekAlert! Science News
A University of Queensland-led international study has discovered a new type of bacterial structure which has previously only been seen in more complex cells. Research team leader UQ School of Chemistry and Molecular Biosciences microbiologist Emeritus Professor John Fuerst said the study had found pore-like structures in a bacterium called Gemmata obscuriglobus.
NIH Lambda Lunch Meetings
Subject: Lambda Lunch update To: [email protected] Lambda Lunch update, 1/29/08: 1/29/08, Noon, Building 32TII Conference Room: Emily Troemel (Fred Ausubel lab, MGH) Host/pathogen interactions in C. elegans 1/29/08, 2:15 PM, 37/2041: Heather W. Pinkett, (Caltech) Structural Studies of an ABC Transporter from Haemophilus influenzae, HIF 1/31/08*: Bob Schleif (Hopkins) Pursuing a Proteins Innermost Secrets: AraC (Sankar Adhya) 2/7/08*: Christophe Penno (Cashel lab) Control of the virulence of Shigella flexneri by transcriptional slippage 2/8/08, Noon, Building 32TII Conference Room: Jennifer Philips (Perrimon + Rubin labs, Harvard Med) Genome-wide RNAi screen in Drosophila identifies host factors that modulate Mycobacterial infection 2/8/08, 9 AM - 12 PM, Natcher (Building 45) Room E1/E2: Imaging Bacterial Structures: A Symposium in Honor of Martin Kessel. Register at http://www.csmicro.org/html/CSM_Winter08_Symposium.htm 3/7/08: 12:00 PM, 32TII/Conf. room: Petra Levin (Wash ...
Jons Text: February 2013
Every cell in your body does this at a low level. But pressurised cancer cells do it at 100 times that level! So do the bacterial structures cluster around the coronary arteries and the kidneys that cause coronary heart disease. As do the viral structures in the pancreas causing diabetes ...
The Gilets That Will Let You Layer Like A Lord When Autumn Arrives
A long shower is one of the most simple yet effective forms of self-care. Scorching water, serenity and most importantly a break from staring at a screen are always welcomed. Washing your hair, however? Not so much. Dont get me wrong; hair washing is a very normal activity and deserves little to no disdain. But it still sucks, especially for me. The bitterness started when I was at school. My hair is naturally curly and back then, it was incredibly long and thick (bounteous, even, pre-bleach). I straightened it 24/7, so the entire routine was exhausting. Each week was planned around wash day, which usually took place on Thursday night so I was set for the weekend. Any activities that coincided were swiftly cancelled. I cant come, Im washing my hair, was a frequently used yet totally legitimate excuse. It took ages and I learned to loathe it. Today, Im free from the constraints of my straighteners and I mostly let my hair do its own thing. But the washing aversion? Thats still there.When ...
The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by...
Blumenthal A., Ehlers S., Lauber J., Buer J., Lange C., Goldmann T., Heine H., Brandt E., Reiling N.. Microarray--assisted gene--expression screens of human macrophages revealed WNT5A, a homolog of Wingless, a key regulator of Drosophila melanogaster embryonic segmentation and patterning, to be consistently up-regulated following stimulation with different mycobacterial species and conserved bacterial structures. The expression of WNT5A required Toll-like receptor signaling and NF-kappaB activation, which identifies a novel induction pathway for a Wingless homolog. We show that human peripheral-blood mononuclear cells express the WNT5A receptor Frizzled-5 (FZD5). Both WNT5A and FZD5 also were detected in granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected patients. Functional studies showed that WNT5A and FZD5 regulate the microbially induced interleukin-12 response of antigen-presenting cells and interferon-gamma production by mycobacterial antigen-stimulated T cells. Our ...
Table of Contents - Online Textbook of Bacteriology
Todars Online Textbook of Bacteriology chapters on bacteriology, microbes in the environment, cycles of elements, bacterial structure, bacterial nutrition, bacterial growth, bacterial metabolism, bacteria and archaea, normal flora, bacterial pathogens, bacterial toxins, endotoxin, antibiotics, antibiotic resistance, staphylococci and MRSA, streptococcus, pneumonia, anthrax, E. coli, cholera, Salmonella, Pseudomonas, Shigella, gonorrhea, meningococcal meningitis, botulism and tetanus hib meningitis, Listeria, whooping cough, B. cereus food poisoning, tuberculosis, diphtheria, Rocky Mountain spotted fever, Lyme disease, Vibrio vulnificus, Bacillus, lactic acid bacteria.
NCTC - Biology
This course covers basic microbiology and immunology and is primarily directed at pre-nursing, pre-allied health, and non-science majors. It provides an introduction to historical concepts of the nature of microorganisms, microbial diversity, the importance of microorganisms and acellular agents in the biosphere, and their roles in human and animal diseases. Major topics include bacterial structure as well as growth, physiology, genetics, and biochemistry of microorganisms. Emphasis is on medical microbiology, infectious diseases, and public health.. This course covers basics of culture and identification of bacteria and microbial ecology. This course is primarily directed at pre-nursing and other pre-allied health majors and covers basics of microbiology. Emphasis is on medical microbiology, infectious diseases, and public health.. Read More. ...
The Laughable Delusion Of Sarah Wollaston MP
Civil Servant: So, yeah, trying to explain modelling and, you know, elasticities and all of that, I mean, I find it difficult to get my head around that, so, you know, not surprising that thats quite a difficult thing to explain to the public, media, you know, committee, especially when people dont necessarily want to believe it either, you know? […] but I guess its like all of these things that, you know, were not very good, were not very literate with uncertainties and, you know, like we always say about risk, you know, people find it really hard to get their head round … ...
KEGG PATHWAY: Methane metabolism - Gallionella capsiferriformans
Methane is metabolized principally by methanotrophs and methanogens in the global carbon cycle. Methanotrophs consume methane as the only source of carbon, while methanogens produce methane as a metabolic byproduct. Methylotrophs, which are microorganisms that can obtain energy for growth by oxidizing one-carbon compounds, such as methanol and methane, are situated between methanotrophs and methanogens. Methanogens can obtain energy for growth by converting a limited number of substrates to methane under anaerobic conditions. Three types of methanogenic pathways are known: CO2 to methane [MD:M00567], methanol to methane [MD:M00356], and acetate to methane [MD:M00357]. Methanogens use 2-mercaptoethanesulfonate (CoM; coenzyme M) as the terminal methyl carrier in methanogenesis and have four enzymes for CoM biosynthesis [MD:M00358]. Coenzyme B-Coenzyme M heterodisulfide reductase (Hdr), requiring for the final reaction steps of methanogenic pathway, is divided into two types: cytoplasmic HdrABC in ...
Darwin and Consciousness of Others - Durham University
Isolation and characterization of an outer membrane protein of salmonella paratyphi B: a mitogen and polyclonal activator of...
Salmonella paratyphi B (S. paratyphi B) has been previously characterized as a human T-independent polyclonal B cell activator. Furthermore, the bacterium spontaneously binds to the cell membranes of approximately 60% of the total human peripheral blood lymphocyte (PBL) population, including all of the immunoglobulin positive (Ig+) cells. To define further the nature of the bacterial structures responsible for these properties, the effects of autoclaving and enzyme treatment of the bacterium were studied with regard to its polyclonal activation properties and binding to lymphocytes. Both autoclaving and papain treatment decreased the ability of S. paratyphi B to induce B cell activation as assessed by either: a) the accumulation of immunoglobulin in cell culture supernatants quantitated by laser nephelometry, or b) the generation of immunoglobulin secreting cells as enumerated by the reverse hemolytic plaque assay. Trypsin treatment did not affect the stimulating capacity of S. paratyphi B. None ...
bacteria list for Keniworth BioBlitz
Iron bacteria: Gallionella ferruginea Leptothrix cholodnii Leptothrix discophora Leptothrix ochracea Leptothrix ochracea-type Leptothrix sp.A (intermediate between L. ochracea and L. cholodnii) Siderocapsa cf. treubii Siderocystis sp. Cyanobacteria: Oscillatoria sp. Spirulina sp. SEE wild bacteria and other micro-organisms up close on a guided slide show of the seemy underworld of the Kenilworth Aquatic Gardens ...
Cross-talk between individual phenol-soluble modulins in Staphylococcus aureus biofilm enables rapid and efficient amyloid...
Inter-molecular cross-seeding between phenol-soluble modulins facilitates rapid and efficient self-assembly in Staphylococcus aureus biofilms revealing a complex molecular interplay between distinct phenol-soluble modulins orchestrating functional amyloid formation.
Kojima S, Blair DF (2004). The bacterial flagellar motor: structure and function of a complex molecular machine. International ... Structure and contents of a typical Gram-positive bacterial cell (seen by the fact that only one cell membrane is present). ... Intracellular structures. The bacterial cell is surrounded by a cell membrane, which is made primarily of phospholipids. This ... Two other types of bacterial motion are called twitching motility that relies on a structure called the type IV pilus, and ...
Bacterial exotoxic proteases destroy extracellular structures. Viruses. Some viruses express their entire genome as one ... A secreted bacterial protease may also act as an exotoxin, and be an example of a virulence factor in bacterial pathogenesis ( ... The structure of a protease (TEV protease) complexed with its peptide substrate in black with catalytic residues in red.(PDB: ... Bacterial and fungal proteases are particularly important to the global carbon and nitrogen cycles in the recycling of proteins ...
Anatomical terms of location
Structures closer to the radius are radial, structures closer to the ulna are ulnar, and structures relating to both bones are ... Similarly, in the lower leg, structures near the tibia (shinbone) are tibial and structures near the fibula are fibular (or ... These terms refer to the distance of a structure from the surface or structure. ... describes structures close to the midline, or closer to the midline than another structure. For example, in a human, the ...
Maina, John N. (2005). The lung air sac system of birds development, structure, and function ; with 6 tables. Berlin: Springer ... The structures that act as the bellows which ventilate the lungs, are the air sacs distributed throughout much of the birds' ... Proctor, N. S. & Lynch, P. J. (1998) Manual of Ornithology: Avian Structure & Function. Yale University Press. ISBN 0300076193 ... Bird anatomy, or the physiological structure of birds' bodies, shows many unique adaptations, mostly aiding flight. Birds have ...
Smith, Patricia; Tchernov, Eitan (1992). Structure, Function and Evolution of teeth. Freund Publishing House Ltd. p. 217. ISBN ... The cat's oral structures provide for a variety of vocalizations used for communication, including meowing, purring, hissing, ... The stomach is not only a muscular structure, it also serves a chemical function by releasing hydrochloric acid and other ...
Bacterial cell structure. References. *^ John G. Holt; Noel R. Krieg; Peter H.A. Sneath; James T. Staley; Stanley T. ... See also: Gram-negative bacterial infection and Gram-positive bacterial infection. Gram stains are performed on body fluid or ... Gram stain or Gram staining, also called Gram's method, is a method of staining used to distinguish and classify bacterial ... Gram staining is a bacteriological laboratory technique used to differentiate bacterial species into two large groups (gram- ...
The structure and tissues of plants are of a dissimilar nature and they are studied in plant anatomy. ... Study of small structures involved passing light through them and the microtome was invented to provide sufficiently thin ... Before the modern medical era, the main means for studying the internal structures of the body were dissection of the dead and ... About the same time, in the 1950s, the use of X-ray diffraction for studying the crystal structures of proteins, nucleic acids ...
... these are the form and proportions of the human body and the surface landmarks which correspond to deeper structures hidden ...
Eukaryotic small ribosomal subunit (40S)
Structure (Eukaryotic) H. sapiens Conservation S. cerevisiae Bacterial homolog (E. coli) Archaeal homolog ... Structure of the T. thermophila,' proteins from the structures of the large subunit PDBS 417, 4A19 and small subunit PDB 2XZM ... Overall structure. The shape of the small subunit can be subdivided into two large segments, the head and the body. ... In the figure "Crystal Structure of the Eukaryotic 40S Ribosomal Subunit from T. thermophila", the ribosomal RNA core is ...
Silva MT, Sousa JC, Polónia JJ, Macedo MA, Parente AM (1976). "Bacterial mesosomes. Real structures or artifacts?". Biochim. ... These structures are invaginations of the plasma membrane observed in gram-positive bacteria that have been chemically fixed to ... were recognized as artifacts by the late 1970s and are no longer considered to be part of the normal structure of bacterial ... Culp, S. (1994). "Defending Robustness: The Bacterial Mesosome as a Test Case". PSA: Proceedings of the Biennial Meeting of the ...
... which are very different from those of the eukaryotic chromosomes in structure and function. The known structures of bacterial ... Maloy S (July 12, 2002). "Bacterial Chromosome Structure". Retrieved 2008-06-22. Martínez P, Blasco MA (October 2010). "Role of ... This triple-stranded structure is called a displacement loop or D-loop. Telomere shortening in humans can induce replicative ... Telomeres form large loop structures called telomere loops, or T-loops. Here, the single-stranded DNA curls around in a long ...
This common structure may reflect a common evolutionary origin as part of ribozymes in an ancient RNA world. It has been ... Salisbury SA, Forrest HS, Cruse WB, Kennard O (August 1979). "A novel coenzyme from bacterial primary alcohol dehydrogenases". ... Many contain the nucleotide adenosine monophosphate (AMP) as part of their structures, such as ATP, coenzyme A, FAD, and NAD+. ... Frank RA, Leeper FJ, Luisi BF (2007). "Structure, mechanism and catalytic duality of thiamine-dependent enzymes". Cell. Mol. ...
Fisher AJ, Thompson TB, Thoden JB, Baldwin TO, Rayment I (Sep 1996). "The 1.5-A resolution crystal structure of bacterial ... Baldwin TO, Christopher JA, Raushel FM, Sinclair JF, Ziegler MM, Fisher AJ, Rayment I (Dec 1995). "Structure of bacterial ... The structure of the dinoflagellate luciferase catalytic domain has been solved. The core part of the domain is a 10 stranded ... The helical bundle domain has a three helix bundle structure that holds four important histidines that are thought to play a ...
"GSI structure". Archived from the original on 2008-12-17. Retrieved 2009-03-31.. ... Brown JR, Masuchi Y, Robb FT, Doolittle WF (June 1994). "Evolutionary relationships of bacterial and archaeal glutamine ... The C-terminus (helical thong) stabilizes the GS structure by inserting into the hydrophobic region of the subunit across in ... van Rooyen JM, Abratt VR, Sewell BT (August 2006). "Three-dimensional structure of a type III glutamine synthetase by single- ...
November 2005). "Structures of the bacterial ribosome at 3.5 A resolution". Science. 310 (5749): 827-34. doi:10.1126/science. ... High-resolution structure. Figure 4 : Atomic structure of the 50S subunit from Haloarcula marismortui. Proteins are shown ... Due to the differences in their structures, the bacterial 70S ribosomes are vulnerable to these antibiotics while the ... The general molecular structure of the ribosome has been known since the early 1970s. In the early 2000s, the structure has ...
Membrane Proteins of known 3D Structure *^ Elofsson, A.; Heijne, G. V. (2007). "Membrane Protein Structure: Prediction versus ... Bacterial photosynthetic reaction centres and photosystems I and II. *Light-harvesting complexes from bacteria and chloroplasts ... Classification by structure. There are two basic types of transmembrane proteins: alpha-helical and beta-barrels. ... 3D structures. See also: Transporter Classification Database. Light absorption-driven transporters. * ...
"Eukaryotic Chromosome Structure , Science Primer". scienceprimer.com. Retrieved 2015-11-22.. *^ a b Smith, Dwight G (2015). ... The endosymbiotic theory holds that mitochondria and chloroplasts have bacterial origins. Both organelles contain their own ... Johnston C, Martin B, Fichant G, Polard P, Claverys JP (2014). "Bacterial transformation: distribution, shared mechanisms and ... Transformation is a bacterial process for transferring DNA from one cell to another, and is apparently an adaptation for ...
"Yeast alcohol dehydrogenase structure and catalysis". Biochemistry. 53: 5791-803. doi:10.1021/bi5006442. PMC 4165444. PMID ... "Bacterial Fermentation" (PDF). eLS. John Wiley & Sons, Ltd. doi:10.1038/npg.els.0001415. ISBN 9780470015902 ...
"Tertiary structure of bacterial selenocysteine tRNA". Nucleic Acids Research. 41 (13): 6729-38. doi:10.1093/nar/gkt321. PMC ... The structure of tRNA can be decomposed into its primary structure, its secondary structure (usually visualized as the ... cloverleaf structure), and its tertiary structure (all tRNAs have a similar L-shaped 3D structure that allows them to fit ... "Structures of the bacterial ribosome in classical and hybrid states of tRNA binding". Science. 332 (6032): 981-4. Bibcode: ...
Hitchen PG, Dell A (June 2006). "Bacterial glycoproteomics". Microbiology. 152 (Pt 6): 1575-80. doi:10.1099/mic.0.28859-0. PMID ... Dell A, Morris HR (March 2001). "Glycoprotein structure determination by mass spectrometry". Science. 291 (5512): 2351-6. ... techniques that allow more detailed structures to be observed in the study of Glycobiology. Tate and Lyle Medal, Royal Society ... is an Australian biochemist specialising in the study of glycomics and the carbohydrate structures that modify proteins. Anne's ...
Raymond L. Rodriguez
Promoters: Structure and Function. R.L. Rodriguez and M.J. Chamberlin eds. Praeger Scientific, New York, 1982. Rodriguez, R.L. ... A bacterial clone synthesizing proinsulin. Proceedings of the National Academy of Sciences of the United States of America, 75( ... Organization, structure and expression of the rice alpha-amylase multigene family. In, Rice Genetics II. Manila, pp. 417-429. ... Structure and Function" 1982 with M.J. Chamberlin and "Vectors: A Survey of Molecular Cloning Vectors," 1987 with D.T. Denhardt ...
Klemm, Per; Schembri, Mark A. (2000). "Bacterial adhesins: function and structure". International Journal of Medical ... In multicellular organisms, bindings between CAMs allow cells to adhere to one another and creates structures called cell ... Prokaryotes have adhesion molecules on their cell surface termed bacterial adhesins, apart from using its pili (fimbriae) and ... Integrins are transmembrane heterodimers formed by different α and β subunits, both subunits with different domain structures. ...
1A2M Structure Summary". Structure. 6: 757-767. doi:10.2210/pdb1a2m/pdb. Retrieved 11 July 2012. Kadokura H, Beckwith J ( ... DsbA is a bacterial thiol disulfide oxidoreductase (TDOR). DsbA is a key component of the Dsb (disulfide bond) family of ... Heras B, Shouldice SR, Totsika M, Scanlon MJ, Schembri MA, Martin JL (March 2009). "DSB proteins and bacterial pathogenicity". ... Guddat LW, Bardwell JC, Martin JL (June 1998). "Crystal structures of reduced and oxidized DsbA: investigation of domain motion ...
Lizak C, Gerber S, Numao S, Aebi M, Locher KP (June 2011). "X-ray structure of a bacterial oligosaccharyltransferase". Nature. ... Structure and function. Yeast OST is composed of eight different membrane-spanning proteins in three subcomplexes (one of ... Pfeffer S, Dudek J, Gogala M, Schorr S, Linxweiler J, Lang S, Becker T, Beckmann R, Zimmermann R, Förster F (2014). "Structure ... Wild R, Kowal J, Eyring J, Ngwa EM, Aebi M, Locher KP (2018). "Structure of the yeast oligosaccharyltransferase complex gives ...
Douglas H. Turner
Seetin, M. G.; Mathews, D. H. (2012). "RNA Structure Prediction: An Overview of Methods". Bacterial Regulatory RNA. Methods in ... This has helped advance methods for predicting RNA structure from sequence, as well as RNA-RNA interactions: e.g. miRNA or ... In his own lab, these methods were used to discover potentially medically important RNA structures in influenza virus including ... Turner, D H; N Sugimoto; S M Freier (1988). "RNA Structure Prediction". Annual Review of Biophysics and Biophysical Chemistry. ...
Xavier Didelot (2010). "Sequence-Based Analysis of Bacterial Population Structures". In D. Ashley Robinson; Daniel Falush; ... Edward J. Feil (eds.). Bacterial Population Genetics in Infectious Disease. John Wiley and Sons. pp. 46-47. ISBN 978-0-470- ...
"Structure and Function of Bacterial Cells". textbookofbacteriology.net. Bardy S, Ng S, Jarrell K (2003). "Prokaryotic motility ... The cell structures that provide the ability for locomotion are the cilia and flagella. Coliform and Streptococci are examples ... An inoculating needle (not a loop) is used to insert the bacterial sample. The needle is inserted through the medium for a ... Non-motile bacteria are bacteria species that lack the ability and structures that would allow them to propel themselves, under ...
Early studies elucidated the structure of parts of bacterial condensins, such as MukBEF and SMC-ScpA. In eukaryotic complexes, ... It has also been shown that condensins can assemble chromosome-like structures in cell-free extracts even under the condition ... Recent studies report the occurrence of a third complex related to MukBEF (termed MksBEF) in some bacterial species. SMC dimers ... This peculiarity could be due to the fact that C. elegans has a specialized chromosome structure known as holocentric ...
Falke, J; Dernburg, AF; Sternberg, DA; Zalkin, N; Milligan, DL; Koshland, DE (1988-11-01). "Structure of a bacterial sensory ... where she co-authored a study analyzing the structure of a bacterial sensory receptor. Dernburg then entered the Tetrad Program ... Using live cell imaging they discovered that the synaptonemal complex, the special structure that holds together homologous ... studying bacterial chemotaxis, or how cells and organisms move in response to a chemical stimulus. Following graduation, she ...
how community structure, function and stability is determined.. Ecological pyramids. See also: Ecological pyramid ... "Bacterial biomineralization: new insights from Myxococcus-induced mineral precipitation". Geological Society, London, Special ... Pyramid structure can vary across ecosystems and across time. In some instances biomass pyramids can be inverted. This pattern ... At different levels in the hierarchy of life, such as the stability of a food web, "the same overall structure is maintained in ...
The genome of S. pneumoniae is a closed, circular DNA structure that contains between 2.0 and 2.1 million base pairs depending ... Natural bacterial transformation involves the transfer of DNA from one bacterium to another through the surrounding medium. ... van de Beek, Diederik; de Gans, Jan; Tunkel, Allan R.; Wijdicks, Eelco F.M. (5 January 2006). "Community-Acquired Bacterial ... Type strain of Streptococcus pneumoniae at BacDive - the Bacterial Diversity Metadatabase ...
Positron emission tomography
Three different PET contrast agents have been developed to image bacterial infections in vivo: [18F]maltose, [18F] ... This is very useful in showing detailed views of moving organs or structures with higher anatomical variation, which is more ... The result is that structures deep in the body are reconstructed as having falsely low tracer uptake. Contemporary scanners can ... Changing of regional blood flow in various anatomic structures (as a measure of the injected positron emitter) can be ...
... balance as well as treating any bacterial infections that may develop. Dialysis may be needed for kidney failure, and ... which reduces the availability of specific integrins responsible for cell adhesion to the intercellular structure and causes ...
Organulo, ang malayang ensiklopedya
"Protein structures forming the shell of primitive bacterial organelles.". Science 309 (5736): 936-8. Bibcode 2005Sci...309.. ...
Linear structureEdit. Chloroplast DNA has long been thought to have a circular structure, but some evidence suggests that ... Because it is similar to bacterial amino acid transporters and the mitochondrial import protein Tim17 (translocase on the i ... Molecular structureEdit. The 154 kb chloroplast DNA map of a model flowering plant (Arabidopsis thaliana: Brassicaceae) showing ... Wise RR, Hoober JK (2007). Structure and function of plastids. Berlin: Springer. pp. 53-74. ISBN 978-1-4020-6570-5. .. ...
Hyphae penetrate to the depth of the stratum spinosum, and appear as weakly basophilic structures. Polymorphonuclear cells also ... "Medically important bacterial-fungal interactions." Nature Reviews Microbiology 8.5 (2010): 340-349. Kourkoumpetis, ...
Abortion - Simple English Wikipedia, the free encyclopedia
Koba S, Nowak S (February 1976). "[A case of acute bacterial dysentery with cerebrospinal meningitis]" (in Polish). Wiadomości ... Abortion would interrupt this process, leaving in the gland undifferentiated structures like those observed in the rat mammary ...
The bacterial cell's control system has a hierarchical organization. The signaling and the control subsystem interfaces ... Caulobacter crescentus is a member of a group of bacteria that possess the stalk structure, a tubular extension from the cell ... Generally, the bacterial species that divides fastest will be most effective at exploiting resources and effectively occupying ... The other daughter, called the "stalked" cell, has a tubular stalk structure protruding from one pole that has an adhesive ...
The reason for polishing is a result of the composition and structure of the rice grain itself. The core of the rice grain is ... The government started hailing the use of enamel tanks as easy to clean, lasting forever, and being devoid of bacterial ...
2010). "Chapter 6, Structure, Function and Biogenesis of the Borrelia Cell Envelope". Borrelia: Molecular Biology, Host ... In the US, the National Institutes of Health has supported research into bacterial persistence. ... Dotters-Katz, S; Kuller, J; Heine, P (September 2013). "Arthropod-Borne Bacterial Diseases in Pregnancy". Obstetrical & ... Successful infection of the mammalian host depends on bacterial expression of OspC. ...
The distinctive odor of feces is due to bacterial action. Gut flora produces compounds such as indole, skatole, and thiols ( ... Enzymes in the dog feces helped to relax the fibrous structure of the hide before the final stages of tanning. ...
Structure. Humans are born with four types of tonsils: the pharyngeal tonsil, two tubal tonsils, two palatine tonsils and ... or if bacterial in origin, antibiotics, e.g. amoxicillin and azithromycin. Surgical removal (tonsillectomy) may be advised if ...
An endospore is a dormant, tough, and non-reproductive structure produced by some bacteria in the phylum Firmicutes. The ... Abel-Santos, E (editor) (2012). Bacterial Spores: Current Research and Applications. Caister Academic Press. ISBN 978-1-908230- ... Structure. Variations in endospore morphology: (1, 4) central endospore; (2, 3, 5) terminal endospore; (6) lateral ... Henriques AO, Moran CP Jr (2007). "Structure, assembly, and function of the spore surface layers". Annu Rev Microbiol. 61: 555- ...
David W. Deamer
Loman, N.J.; Quick, J.; Simpson, J.T. (2015). "A complete bacterial genome assembled de novo using only nanopore sequencing ... Deamer, D.W. (1985). "Boundary structures are formed by organic compounds of the Murchison carbonaceous chondrite". Nature. 317 ...
Examples in natural systems of SI include ant colonies, bird flocking, animal herding, bacterial growth, fish schooling and ... The agents follow very simple rules, and although there is no centralized control structure dictating how individual agents ...
RNA polymerase - Simple English Wikipedia, the free encyclopedia
All are similar and related to each other and to bacterial RNAP:. *RNA polymerase I synthesizes a pre-rRNA which will form the ... Structure of eukaryotic RNA polymerase II (light blue) in complex with α-amanitin (red), a strong poison found in death cap ... Eukaryotic chloroplasts have an RNAP very similar to bacterial RNAP ("plastid-encoded polymerase"). Eukaryotic chloroplasts ...
... which is a eucaryotic receptor for bacterial surface structures such as lipoteichoic acid. ... Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a ... Therefore, macrophage membranes become susceptibile to bacterial infections. Reproductive system. In experiments with ... "Crystal and molecular structure of a benzo-a-pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: Absolute configuration and ...
Diseases may also be vectored by invasive insects such as the Asian citrus psyllid and the bacterial disease citrus greening.[ ... Therefore, besides their economic ramifications, alien invasions may result in extensive changes in the structure, composition ... Citrus greening is a bacterial disease vectored by the invasive Asian citrus psyllid (ACP). Because of the impacts of this ... "Population structure and genetic diversity of invasive Phyla canescens: implications for the evolutionary potential". Ecosphere ...
... family members are homologous to the bacterial RecA, Archaeal RadA and yeast Rad51. The protein is highly conserved ... "Insights into DNA recombination from the structure of a RAD51-BRCA2 complex". Nature. 420 (6913): 287-93. doi:10.1038/ ... "The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51". The EMBO Journal. 18 (22): 6552-60. ... Structure. 14 (6): 983-92. doi:10.1016/j.str.2006.04.001. PMID 16765891.. ...
Integral membrane protein
Determination of protein structureEdit. The Protein Structure Initiative (PSI), funded by the U.S. National Institute of ... As an example of the relationship between the IMP (in this case the bacterial phototrapping pigment, bacteriorhodopsin) and the ... StructureEdit. Three-dimensional structures of ~160 different integral membrane proteins have been determined at atomic ... In addition, structures of many water-soluble protein domains of IMPs are available in the Protein Data Bank. Their membrane- ...
The D-alanine in peptidoglycans that comprise bacterial cell walls helps its host resist attack by proteolytic enzymes. Several ...
Structure. Glucans are arranged in six-sided D-glucose rings connected linearly at varying carbon positions depending on ... Mcintosh, M (19 October 2004). "Curdlan and other bacterial (1→3)-β-D-glucans". Applied Microbiology and Biotechnology. 68 (2 ... β-Glucan Structure by Source Source (Example) Backbone Branching Solubility in Water ... Differences in molecular weight, shape, and structure of β-glucans dictate the differences in biological activity. ...
Structure and function. This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels ... Soldatov NM (Jul 1994). "Genomic structure of human L-type Ca2+ channel". Genomics. 22 (1): 77-87. doi:10.1006/geno.1994.1347. ... Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacological Reviews. 57 (4): 411-25. ... Soldatov NM, Zühlke RD, Bouron A, Reuter H (Feb 1997). "Molecular structures involved in L-type calcium channel inactivation. ...
These compounds differ in structure from bacterial antibiotics, so they may have novel modes of action. In addition, they may ... Ester-linked lipids, various structures. Gene structure. Circular chromosomes, similar translation and transcription to Eukarya ... and physical structure, but pseudopeptidoglycan is distinct in chemical structure; it lacks D-amino acids and N-acetylmuramic ... while archaeal flagella appear to have evolved from bacterial type IV pili. In contrast to the bacterial flagellum, which ...
Bioluminescence - Simple English Wikipedia, the free encyclopedia
If you go into a hospital and have a blood test which measures viral proteins, cancer proteins, hormones, vitamins, bacterial ... The structure of photophores, the light producing organs in bioluminescent organisms, are being investigated by industrial ... Members of the marine bacterial family Shewanellaceae, Shewanella hanedai and Shewanella woodyi are bioluminescent. ... In some squid species bacterial bioluminescence is used for counterillumination so the animal matches the overhead ...
Structure. Sequence and prevalence. Figure 2. Mechanism for transcription initiation at the TATA box. Transcription ... bacterial RNA polymerase: rpoB. *eukaryotic RNA polymerase: RNA polymerase II. Termination. (bacterial,. eukaryotic). * ... Kim Y, Geiger JH, Hahn S, Sigler PB (October 1993). "Crystal structure of a yeast TBP/TATA-box complex". Nature. 365 (6446): ... Kim JL, Nikolov DB, Burley SK (October 1993). "Co-crystal structure of TBP recognizing the minor groove of a TATA element". ...
... commenced research on the use of Melaleuca alternifolia in agriculture for the management and control of bacterial and fungal ... activity of Melaleuca alternifolia resulted from its ability to disrupt the permeability barrier in membrane structures. In ...
Single particle analysis
This bacterial protein complex is a machine for folding other proteins, which get trapped within the shell. Fatty acid synthase ... These often enable the user to manually dock in protein coordinates (structures from X-ray crystallography or NMR) of subunits ... Arias-Palomo E, Recuero-Checa MA, Bustelo XR, Llorca O (December 2007). "3D structure of Syk kinase determined by single- ... "3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry". Cell. 141 (3): 472-82. doi:10.1016 ...
Bacterial protein structures reveal phylum dependent divergence. - PubMed - NCBI
Bacterial protein structures reveal phylum dependent divergence.. Shortridge MD1, Triplet T, Revesz P, Griep MA, Powers R. ... that the two Firmicutes structures have highly overlapping structures and (B) that the four Proteobacteria structures are very ... Structure changes measured using a structure similarity ratio (θFSS), where the average FSS between members of the two phyla ( ... Protein structure phylogenies of 4 COGs out of 48 had a strong split pattern with the exception of one outlier structure. The ...
Recombination and the population structures of bacterial pathogens. - PubMed - NCBI
The population structures of bacterial species are complex and often controversial. To a large extent, this is due to ... Recombination and the population structures of bacterial pathogens.. Feil EJ1, Spratt BG. ... The existence of clones within bacterial populations, and of linkage disequilibrium between alleles at different loci, is often ... These studies indicate that in many bacterial species, including Neisseria meningitidis, Streptococcus pneumoniae, and ...
Bacterial Structures, Monerans (Prokaryotes) Microscope Slides | Carolina.com
Bacterial Structures, Monerans (Prokaryotes) Microscope Slides. 5 Items Bacterial Structures, Monerans (Prokaryotes) Microscope ... Bacterial Flagella Slide, Polar Amphitrichous, w.m. Item #294198 $12.85Qty Discount Available ... Bacterial Spores, w.m. Microscope Slide Item #294228 $7.65Qty Discount Available ... Bacterial Flagella Slide, Peritrichous, w.m. Item #294204 $12.15Qty Discount Available ...
Defined spatial structure stabilizes a synthetic multispecies bacterial community | PNAS
Defined spatial structure stabilizes a synthetic multispecies bacterial community. Hyun Jung Kim, James Q. Boedicker, Jang Wook ... Defined spatial structure stabilizes a synthetic multispecies bacterial community. Hyun Jung Kim, James Q. Boedicker, Jang Wook ... Defined spatial structure stabilizes a synthetic multispecies bacterial community Message Subject (Your Name) has sent you a ... Defined spatial structure stabilizes a synthetic multispecies bacterial community. Hyun Jung Kim, James Q. Boedicker, Jang Wook ...
Crystal structure of a bacterial homologue of the kidney urea transporter | Nature
report the X-ray crystal structure of a bacterial homologue of the urea transporter, from Desulfovibrio vulgaris. The ... Here we present the 2.3 Å structure of a functional urea transporter from the bacterium Desulfovibrio vulgaris. The transporter ... Here, the X-ray crystal structure of a functional urea transporter from the bacterium Desulfovibrio vulgaris is presented and ... Crystal structure of a bacterial homologue of the kidney urea transporter *Elena J. Levin1. , ...
Secondary Structure Preferences of Mn2+ Binding Sites in Bacterial Proteins
"Random coil structures in bacterial proteins. Relationships of their amino acid compositions to flanking structures and ... Secondary Structure Preferences of Mn2+ Binding Sites in Bacterial Proteins. Tatyana Aleksandrovna Khrustaleva ... There are just a few apo structures available for Mn2+ coordinating bacterial proteins. Even though changes induced by Mn2+ ... Secondary Structure of the Region around the Histidine Involved in Mn2+ Binding. Preferable secondary structure around ...
Bacterial cell structure
... despite their apparent simplicity contain a well developed cell structure which is responsible for many of their unique ... 6 Intracellular bacterial cell structures *6.1 The bacterial chromosome and plasmids. *6.2 Ribosomes and other multiprotein ... Intracellular bacterial cell structures. In comparison to eukaryotes, the intracellular features of the bacterial cell are ... Flagella are whip-like structures protruding from the bacterial cell wall and are responsible for bacterial motility (i.e. ...
Divergence of Quaternary Structures Among Bacterial Flagellar Filaments | Science
Divergence of Quaternary Structures Among Bacterial Flagellar Filaments. By Vitold E. Galkin, Xiong Yu, Jakub Bielnicki, John ... Divergence of Quaternary Structures Among Bacterial Flagellar Filaments. By Vitold E. Galkin, Xiong Yu, Jakub Bielnicki, John ... Divergence of Quaternary Structures Among Bacterial Flagellar Filaments Message Subject. (Your Name) has forwarded a page to ... The driving force in the change of quaternary structure between Salmonella and Campylobacter may have been the evasion of TLR5. ...
Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction | PNAS
Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction. Astrid Jung, Tatiana ... Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction ... Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction ... Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction ...
RCSB PDB - 2JQT: Structure of the bacterial replication origin-associated protein Cnu
Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These ... Structure of the bacterial replication origin-associated protein Cnu. *DOI: 10.2210/pdb2JQT/pdb ... Structure of the nucleoid-associated protein Cnu reveals common binding sites for H-NS in Cnu and Hha.. Bae, S.H., Liu, D., Lim ... Here, we determined its solution structure and dynamic properties and mapped H-NS binding sites. Cnu consists of three alpha ...
Characterization of Bacterial Community Structure in Rhizosphere Soil of Grain Legumes | SpringerLink
Molecular techniques were used to characterize bacterial community structure, diversity (16S rDNA), and activity (16S rRNA) in ... McCaig, AE, Glover, LA, Prosser, JI 1999Molecular analysis of bacterial community structure and diversity in unimproved and ... Molecular techniques were used to characterize bacterial community structure, diversity (16S rDNA), and activity (16S rRNA) in ... Plant-dependent rhizosphere effects were evident from significant differences in the bacterial community structure of the ...
Bacterial Phylogenetic Clusters Revealed by Genome Structure | Journal of Bacteriology
Bacterial Phylogenetic Clusters Revealed by Genome Structure. Shu-Lin Liu, Anthony B. Schryvers, Kenneth E. Sanderson, Randal N ... Bacterial Phylogenetic Clusters Revealed by Genome Structure. Shu-Lin Liu, Anthony B. Schryvers, Kenneth E. Sanderson, Randal N ... Bacterial Phylogenetic Clusters Revealed by Genome Structure. Shu-Lin Liu, Anthony B. Schryvers, Kenneth E. Sanderson, Randal N ... Roots of bacterial systematics Handbook of new bacterial systematics. Goodfellow M., ODonnell A. G. 1993 3 56 Academic Press ...
Bacterial cell structure - Wikipedia
Flagella are whip-like structures protruding from the bacterial cell wall and are responsible for bacterial motility (i.e. ... The chemical structure of the outer membranes lipopolysaccharide is often unique to specific bacterial sub-species and is ... Pili are similar in structure to fimbriae but are much longer and present on the bacterial cell in low numbers. Pili are ... Endospores are bacterial survival structures that are highly resistant to many different types of chemical and environmental ...
Crystal Structure of Bacterial Multidrug Efflux Transporter AcrB
We have determined the crystal structure of AcrB at 3.5 A resolution. Three AcrB protomers are organized as a homotrimer in the ... Crystal Structure of Bacterial Multidrug Efflux Transporter AcrB Nature. 2002 Oct 10;419(6907):587-93. doi: 10.1038/nature01050 ... The structure implies that substrates translocated from the cell interior through the transmembrane region and from the ... We have determined the crystal structure of AcrB at 3.5 A resolution. Three AcrB protomers are organized as a homotrimer in the ...
RCSB PDB - 4P02: Structure of Bacterial Cellulose Synthase with cyclic-di-GMP bound.
Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These ... Structure of Bacterial Cellulose Synthase with cyclic-di-GMP bound.. *DOI: 10.2210/pdb4P02/pdb ... The bacterial signaling molecule cyclic di-GMP (c-di-GMP) stimulates the synthesis of bacterial cellulose, which is frequently ... The bacterial signaling molecule cyclic di-GMP (c-di-GMP) stimulates the synthesis of bacterial cellulose, which is frequently ...
Conserved structure and domain organization among bacterial Slc26 transporters. | Sigma-Aldrich
Conserved structure and domain organization among bacterial Slc26 transporters.. [Emma L R Compton, Kimberly Page, Heather E ... In a fundamental step towards understanding the structure/function relationships within the family we have used small-angle ... neutron scattering (SANS) on two distantly related bacterial homologues to show that there is a common, dimeric and structural ...
Tertiary Structure of Bacterial Murein: the Scaffold Model | Journal of Bacteriology
Tertiary Structure of Bacterial Murein: the Scaffold Model. Boris A. Dmitriev, Filip V. Toukach, Klaus-Jürgen Schaper, Otto ... Tertiary Structure of Bacterial Murein: the Scaffold Model. Boris A. Dmitriev, Filip V. Toukach, Klaus-Jürgen Schaper, Otto ... Tertiary Structure of Bacterial Murein: the Scaffold Model. Boris A. Dmitriev, Filip V. Toukach, Klaus-Jürgen Schaper, Otto ... Tertiary Structure of Bacterial Murein: the Scaffold Model Message Subject (Your Name) has forwarded a page to you from Journal ...
Crystal structure of the bacterial cell-division protein FtsZ
Bacterial cell division ends with septation, the constriction of the cell wall and cell membranes that leads to the formation ... Crystal structure of the bacterial cell-division protein FtsZ Nature. 1998 Jan 8;391(6663):203-6. doi: 10.1038/34472. ... The three-dimensional structure of FtsZ is similar to the structure of alpha- and beta-tubulin. ... Bacterial cell division ends with septation, the constriction of the cell wall and cell membranes that leads to the formation ...
Microbiological functioning, diversity, and structure of bacterial communities in ultramafic soils from a tropical savanna |...
Bacterial community diversity and structure were studied by sequencing of 16S rRNA gene clone libraries. MBC and enzyme ... We believe this work presents benchmark information on SMF, diversity, and structure of bacterial communities for a unique type ... Microbiological functioning, diversity, and structure of bacterial communities in ultramafic soils from a tropical savanna. ... This study evaluated soil microbiological functioning (SMF), richness, diversity, and structure of bacterial communities from ...
Bacterial Chromosome Structure | Springer for Research & Development
By analogy with protein structure one can potentially describe: (a) a one-dimensional representation... ... The structure of the bacterial chromosome can be considered at several different levels. ... The structure of the bacterial chromosome can be considered at several different levels. By analogy with protein structure one ... Pettijohn D (1988) Histone-like proteins and bacterial chromosome structure. J Biol Chem 263: 12793-12796PubMedGoogle Scholar ...
New antibiotics a step closer with discovery of bacterial protein structure | UCL News - UCL - University College London
Scientists have uncovered the structure of the protein complex that assembles the tiny hair-like strands that cover the outside ... New antibiotics a step closer with discovery of bacterial protein structure. New antibiotics a step closer with discovery of ... The structure of the FimD protein means scientists can see the process of pili assembly, from individual protein subunits to ... The structure of FimD provides insights into pilus biogenesis because it unravels the entire mechanism of subunit ...
The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation | Nature...
However, the structure of the intact cap complex, and the molecular basis for its interaction with the filament, remains ... Here we report the cryo-EM structure of the Campylobacter jejuni cap complex, which reveals that FliD is pentameric, with the N ... FliD forms a cap complex at the tip of bacterial flagella and is essential for flagellum filament assembly. Here, the authors ... whose primary function in bacteria is to facilitate motility through the rotation of a filament protruding from the bacterial ...
Structure of bacterial nanowire protein hints at secrets of ... ( RICHLAND Wash. -- Tiny electrical wi...)
Structure,of,bacterial,nanowire,protein,hints,at,secrets,of,conduction,biological,biology news articles,biology news today, ... Tiny electrical wires protrude from some bacteria a... This is the first atomic resolution structure of this protein from an... ... With the help of related structures on disease-causing bacteria the r... How to get electrons from the inside of bacteria to ... image.bio-medicine.org/img/Structure-of-bacterial-nanowire-protein-hints-at-secrets-of-conduction.gif alt=Structure of ...
British Library EThOS: Nanoscale patterning of complex DNA structures with the bacterial protein Recombinase A
However, it did not prove possible to pattern these structures with RecA. Recombinant RecA production through bacterial ... Nanoscale patterning of complex DNA structures with the bacterial protein Recombinase A ... Attempts to create three-way junctions from these structures were not successful. A second structure was created through ... The bacterial protein Recombinase A (RecA) may be able to provide this function. This thesis will discuss the patterning of DNA ...
Structure of a bacterial ATP synthase | eLife
Construction of a first atomic model for an intact bacterial ATP synthase allows for a structural understanding of the roles of ... In the bacterial ATP synthase structure, the FO subunits ab2 display an organization similar to the yeast FO complex (PDB 6B2Z ... The structures reveal how loops in subunit a of the bacterial enzyme fill the role of additional subunits in the FO region of ... Given that these structures represent resting states of the bacterial ATP synthase, additional subunits, such as those in the ...
Determination of the structures of three bacterial polysaccharides and synthesis and use of new spacers for glycoconjugate...
Bacterial cell division: Researchers elucidate structure of a Z-ring
... in super-resolution microscope technology has allowed Australian researchers rewrite the book on the process of bacterial cell ... Bacterial cell division: Researchers elucidate structure of a Z-ring. by Claire Thompson, University of Technology, Sydney ... Citation: Bacterial cell division: Researchers elucidate structure of a Z-ring (2012, September 12) retrieved 16 July 2019 from ... "It turns out that the Z-ring is a very dynamic beads-on-a-string structure, changing shape constantly as a cell divides. We ...
Frontiers | Drivers of Regional Bacterial Community Structure and Diversity in the Northwest Atlantic Ocean | Microbiology
In this study, the integrated effect of seasonal differences and spatial distribution on bacterial community structure and ... In this study, the integrated effect of seasonal differences and spatial distribution on bacterial community structure and ... to analyze the effects of physicochemical gradients on bacterial community structure. Throughout the region, Pelagibacteraceae ... to analyze the effects of physicochemical gradients on bacterial community structure. Throughout the region, Pelagibacteraceae ...
Frontiers | Mucus Sugar Content Shapes the Bacterial Community Structure in Thermally Stressed Acropora muricata | Microbiology
Changes in mucus composition and the bacterial community in the mucus layer occurred at 29°C, which were prior to visual signs ... induced by thermal stress could therefore be a key factor leading to a shift in the associated bacterial community. This, in ... and determined whether this composition correlated with any changes in the bacterial community. Results showed that, at lower ... and determined whether this composition correlated with any changes in the bacterial community. Results showed that, at lower ...
ProteinsBacteriaSpeciesPeptidoglycanPathogensMetabolismMolecularEnzymeMicrobial communityAcute Bacterial SkinInfectionsSubstratesCrystallographyDifferent bacterialRRNADiversityInteractionsStructuralPopulationsFlagellarCellulosePlasmidSoilMoleculesCharacterizeTypes of bacterialEnzymesChemistryBacteriumMembraneNucleoidDifferencesDynamicsAnti-bacterialKnown bacterialTotal bacterialPurple bacterialCrystal structureSubunitPhylogeneticClostridiumShiftsFlagellumAntibioticsFunctionCommunitiesSpatialPneumoniaStatistically significantReplicationCell wallsDivergenceColiGrowthCompositionCommunity structures
- The structures and sequences of proteins within each COG were compared against each other to establish their relatedness. (nih.gov)
- 3D structures of proteins with coordinated Mn 2+ ions from bacteria with low, average, and high genomic GC-content have been analyzed (149 PDB files were used). (hindawi.com)
- About half of the dry mass of a bacterial cell consists of carbon, and also about half of it can be attributed to proteins. (bionity.com)
- However, the analogy with protein structure should not be carried too far, because the three-dimensional structure of the chromosome appears to be dynamic in its organization and its structural fluctuations may go beyond the kinds of statistical perturbations expected in proteins. (springer.com)
- Furukawa Y, Imada K, Vonderviszt F, Matsunami H, Sano K-I, Kutsukake K, Namba K (2002) Interactions between bacterial flagellar axial proteins in their monomeric state in solution. (springer.com)
- When proteins are exposed to stresses like a heat shock, they lose their native structure and form toxic insoluble aggregations. (technologynetworks.com)
- Bacterial molecular chaperone ClpB and its yeast homologue Hsp104 have an ability to disentangle and reactivate the aggregated proteins. (technologynetworks.com)
- In addition, the structure provides insights into the mechanism of transcription regulation by the LysR regulatory proteins. (esrf.eu)
- Zooming in on the Geobacter-Gonorrhea composite shows how the aromatic residues (teal balloon-like structures) bulge from the surface of pilin proteins (variously colored helical structures) within the fiber. (pnnl.gov)
- Carboxysomes, which are polyhedral structures on a nanoscale and are comprised of a few different kinds of enzymes and proteins. (labroots.com)
- Using electron microscopy and atomic force microscopy, the investigators then got a look at how the proteins were organized in the structure, and could describe the morphology of these bacterial machines. (labroots.com)
- Nucleotide-binding oligomerization domain proteins-1 and -2 (NOD1 and NOD2) are two members of the 'nucleotide-binding domain and leucine-rich repeat containing' (NLR) protein family [ 1 ], which recognizes bacterial peptidoglycan (PG) ligands [ 2 - 4 ]. (portlandpress.com)
- The structure and dynamics of proteins and nucleic acids are well characterized in vitro, but in vivo crowding effects remain unclear. (elifesciences.org)
- This is particularly true of studies that have examined the arrangement of atoms in large molecules with elaborate structures like proteins or DNA. (elifesciences.org)
- However, cells are densely packed with many different molecules and there is little proof that proteins keep the same structures inside cells that they have when they are studied alone. (elifesciences.org)
- The model shows that some proteins have a much less rigid structure in cells than they do in isolation, whilst others are able to work together more closely to carry out certain tasks. (elifesciences.org)
- Two bacterial microcompartment shell proteins [EtuA (ethanol utilization shell protein A) and EtuB] are found encoded on the genome clustered with the genes for ethanol utilization. (biochemj.org)
- Recent structural studies of bacterial microcompartment proteins have revealed both hexamers and pentamers that assemble to generate the pseudo-icosahedral bacterial microcompartment shell. (biochemj.org)
- The proteins have a recognizable sequence that is referred to as the BMC (bacterial microcompartment) motif. (biochemj.org)
- Some of the shell proteins appear to form a pentameric structure, and these have been proposed to act as the vertices of the icosahedral shell [ 5 , 9 ]. (biochemj.org)
- Type III secretion systems enable plant and animal bacterial pathogens to deliver virulence proteins into the cytosol of eukaryotic host cells, causing a broad spectrum of diseases including bacteremia, septicemia, typhoid fever, and bubonic plague in mammals, and localized lesions, systemic wilting, and blights in plants. (whiterose.ac.uk)
- We constructed a community of three different species of wild-type soil bacteria with syntrophic interactions using a microfluidic device to control spatial structure and chemical communication. (pnas.org)
- To test experimentally the role of microscale spatial structure in bacterial communities, we constructed a synthetic community of three species of wild-type bacteria and used a microfluidic device based on previously described devices ( 14 - 17 ) to control spatial structure and chemical communication within this community. (pnas.org)
- Bacteria , despite their apparent simplicity contain a well developed cell structure which is responsible for many of their unique biological properties. (bionity.com)
- Because of the simplicity of bacteria relative to larger organisms and the ease with which they can be manipulated experimentally, the cell structure of bacteria has been well studied, revealing many biochemical principles that have been subsequently applied to other organisms. (bionity.com)
- Bacteria within the Deinococcus-Thermus group may also exhibit Gram positive staining behaviour but contain some cell wall structures typical of Gram negative organisms. (bionity.com)
- The vertebrate Toll-like receptor 5 (TLR5) recognizes a region of bacterial flagellin that is involved in subunit-subunit assembly in Salmonella and many other pathogenic bacteria, and this short region has diverged in Campylobacter and related bacteria, such as Helicobacter pylori , which are not recognized by TLR5. (sciencemag.org)
- For this purpose, we have devised a strategy enabling us to resolve phylogenetic clusters of bacteria by comparing their genome structures. (asm.org)
- If criteria for defining bacterial species or genera similar to those used for Salmonella and Escherichia coli were applied, the striking phylogenetic diversity would allow bacteria in the currently recognized species of P. multocida and P. haemolytica to be divided into different species, genera, or even higher ranks. (asm.org)
- We conclude that large-scale genome structure can be a sensitive indicator of phylogenetic relationships and that, therefore, I- Ceu I-based genomic mapping is an efficient tool for probing the phylogenetic status of bacteria. (asm.org)
- Bacterial genera or species, as defined by current taxonomic approaches ( 18 , 44 ), may include bacteria that in fact are not closely related phylogenetically. (asm.org)
- Therefore, the ability to efficiently distinguish phylogenetic groups of bacteria within an apparent taxonomic species is desirable, especially for the correct diagnosis and timely treatment of infectious diseases caused by bacterial pathogens. (asm.org)
- Although its composition and fine chemical structure vary in different bacteria ( 52 ), the general principle of its structural organization holds constant. (asm.org)
- Scientists have uncovered the structure of the protein complex that assembles the tiny hair-like strands that cover the outside of bacteria. (ucl.ac.uk)
- Published in Nature, scientists at the Institute of Structural and Molecular Biology (a joint institute between University College London (UCL) and Birkbeck) have revealed the structure of a complex protein called FimD that acts as an assembly platform for the pili of cystitis bacteria. (ucl.ac.uk)
- The structure of FimD provides insights into pilus biogenesis because it unravels the entire mechanism of subunit polymerization and transport across the outer wall of the bacteria. (ucl.ac.uk)
- The bacterial flagellum is a remarkable molecular motor, whose primary function in bacteria is to facilitate motility through the rotation of a filament protruding from the bacterial cell. (nature.com)
- The bacterial flagellum is a macromolecular motor that rotates and acts as a propeller in many bacteria. (nature.com)
- The flagellar filament has been studied extensively by cryo-EM, and its high-resolution structure has been reported in a range of bacteria, including Bacillus subtilis , P. aeruginosa, and S. enterica . (nature.com)
- With the help of related structures on disease-causing bacteria the r. (bio-medicine.org)
- With the help of related structures on disease-causing bacteria, the researchers show that the protein's shape and form suggest possible ways for the bacteria to shuttle electrons along the nanowire. (bio-medicine.org)
- How to get electrons from the inside of bacteria to the outside is important for many different things, such as bacterial fuel cells, how carbon cycles through the environment and how to make new nanomaterials for applications like biocomputers," said Reardon. (bio-medicine.org)
- A group of related bacteria makes these bendy, stretchy structures out of a protein called pilin, and an even smaller group uses these structures like electrical wires. (bio-medicine.org)
- Bacteria produce electrons while respiring and use the wires to run electrons out of their little bacterial bodies. (bio-medicine.org)
- With the original version of the OMX microscope, we could look at the bacteria and get more detail about the Z-ring and its structure, but because the images took a little while to capture, we had to do it on cells that didn't move - we had to kill them to get them to stay still. (phys.org)
- The fundamental role of bacteria in global biogeochemical cycles warrants a thorough understanding of the factors controlling bacterial community structure. (frontiersin.org)
- These bacterial enzymes can alter the activities of RNA molecules and influence the life cycle of bacteria. (helmholtz-berlin.de)
- CHICAGO, May 23, 2014 (GLOBE NEWSWIRE) -- Durata Therapeutics, Inc. (Nasdaq:DRTX) announced today that the U.S. Food and Drug Administration (FDA) has approved DALVANCE TM (dalbavancin) for injection for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). (cnbc.com)
- Melinta Therapeutics announced the availability of oral and intravenous (IV) forms of Baxdela (delafloxacin) for the treatment of adults with acute bacterial skin and skin structure infections (ABSSSI) caused by designated susceptible bacteria. (empr.com)
- The MACs resemble similar syringe structures found on bacteriophages - viruses that infect bacteria - and with evolution, the bacteria have 'stolen' this structure from the phages, and have put it to good use. (scitechdaily.com)
- Phage typically attack bacteria with these structures, but instead of using it to infect other bacteria, the Pseudoalteromonas now uses it to interact with other animals, such as tubeworms, insects, and mouse cells," Shikuma said. (scitechdaily.com)
- MACs are created when the bacteria undergo cell lysis - when the cells blow themselves up - and the bacteria that do this die afterward, so it's almost like altruism because it benefits the rest of the bacterial population. (scitechdaily.com)
- Now, a collaborative research team from the University of East Anglia and Pacific Northwest National Laboratory have determined the structure of the first of these protein components, providing insights into how bacteria live off minerals and rocks. (pnnl.gov)
- The peptides are covalently linked to the glycan chains, and can vary between different bacteria in the nature of the amino acids involved, and in the number and the structure of the peptide cross-links. (cea.fr)
- Moreover, in 2018, Fresenius Kabi received US FDA approval for new drug application of daptomycin, a lipopeptide class of antibacterial drug, in injectable form for complicated skin and skin structure infections (cSSSI) caused by susceptible Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactlae etc. (coherentmarketinsights.com)
- The best characterized of the bacterial microcompartments is the carboxysome, which is a structure associated with carbon fixation that is found in cyanobacteria and many chemotrophic bacteria [ 6 - 9 ]. (biochemj.org)
- A total of 425 isolates of Gram-positive bacteria were obtained consecutively from patients with acute bacterial skin and skin structure infections (ABSSSIs) or pneumonia. (asm.org)
- Uncultivable bacteria were predominant in the total bacterial groups. (ajol.info)
- Bacterial neuraminidase is type of neuraminidase and a virulence factor for many bacteria including Bacteroides fragilis and Pseudomonas aeruginosa. (wikipedia.org)
- The population structures of bacterial species are complex and often controversial. (nih.gov)
- These studies indicate that in many bacterial species, including Neisseria meningitidis, Streptococcus pneumoniae, and Staphylococcus aureus, evolutionary change at neutral (housekeeping) loci is more likely to occur by recombination than mutation and can result in the elimination of any deep-rooted phylogenetic signal. (nih.gov)
- We found that defined microscale spatial structure is both necessary and sufficient for the stable coexistence of interacting bacterial species in the synthetic community. (pnas.org)
- A mathematical model describes how spatial structure can balance the competition and positive interactions within the community, even when the rates of production and consumption of nutrients by species are mismatched, by exploiting nonlinearities of these processes. (pnas.org)
- Cell shape is generally characteristic of a given bacterial species, but can vary depending on growth conditions. (bionity.com)
- In marked contrast, the Pasteurella strains have very different genome structures among and even within individual species. (asm.org)
- On the other hand, strains of Pasteurella ureae and Pasteurella pneumotropica are very similar to those of P. multocida in both genome structure and 16S rDNA sequence and should be regarded as strains within this species. (asm.org)
- Typical examples include: coccus (circle or spherical) bacillus (rod-like) coccobacillus (between a sphere and a rod) spiral (corkscrew-like) filamentous (elongated) Cell shape is generally characteristic of a given bacterial species, but can vary depending on growth conditions. (wikipedia.org)
- Taken together with the range of oligomeric states observed in the FliD crystal structures, these observations have led to a model where in different bacterial species, the cap complex has different oligomeric states (N), and in the corresponding filament, the number of protofilaments is 2N + 1 7 . (nature.com)
- This is the first atomic resolution structure of this protein from an electrically conductive bacterial species, and it sets the foundation for understanding how these nanowires work," said structural biologist Patrick Reardon of the Department of Energy's Pacific Northwest National Laboratory. (bio-medicine.org)
- Many bacterial species wave fingerlike projections along their bodies. (bio-medicine.org)
- In both size fractions, distribution patterns of bacterial taxa, and species within taxa, displayed temporal and spatial preferences. (frontiersin.org)
- Nagoya, Japan - Many bacterial species use spiral propellers (flagella) attached to motors to move through a liquid environment. (researchsea.com)
- We have shown that solid-state 31 P NMR is particularly well adapted to rapidly characterize WTA of different bacterial species, and this both on isolated cell walls or intact bacterial cells. (cea.fr)
- We demonstrated that host species identity is a stronger driver of temperate tree phyllosphere bacterial communities than site or time. (biomedcentral.com)
- Additionally, specific bacterial species were found in the wild and cultivated C. sachalinensis rhizosphere. (ajol.info)
- The bacterial cell wall differs from that of all other organisms by the presence of peptidoglycan (poly- N -acetylglucosamine and N -acetylmuramic acid), which is located immediately outside of the cytoplasmic membrane . (bionity.com)
- Peptidoglycan is responsible for the rigidity of the bacterial cell wall and for the determination of cell shape. (bionity.com)
- While all bacterial cell walls (with a few exceptions e.g. intracellular parasites such as Mycoplasma ) contain peptidoglycan, not all cell walls have the same overall structures. (bionity.com)
- Beta-lactam antibiotics such as penicillin inhibit the formation of peptidoglycan cross-links in the bacterial cell wall. (wikipedia.org)
- Although the chemical structure and physical properties of peptidoglycan have been elucidated for some time, the precise three-dimensional organization of murein has remained elusive. (asm.org)
- Earlier published computer simulations of the bacterial murein architecture modeled peptidoglycan strands in either a regular (D. Pink, J. Moeller, B. Quinn, M. Jericho, and T. Beveridge, J. Bacteriol. (asm.org)
- The major structural component of all types of bacterial walls is murein, the terms murein and peptidoglycan being synonymous. (asm.org)
- The material, regardless of the bacterial cell morphology and the wall thickness, is invariably composed of peptidoglycan strands cross-linked via peptide bridges. (asm.org)
- The most widely used antibiotics ever discovered (beta-lactams) are targeting the enzymes that polymerize peptidoglycan (PG), the essential component of the bacterial cell wall. (findaphd.com)
- Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is an intracellular pattern recognition receptor that recognizes bacterial peptidoglycan (PG) containing meso -diaminopimelic acid ( meso DAP) and activates the innate immune system. (portlandpress.com)
- The peptidoglycan sacculus is an essential component of the bacterial cell wall. (cea.fr)
- Using this technique, different aspects of the bacterial cell wall were investigated, as e.g. protein-peptidoglycan interaction, dynamics of the different biopolymers involved in the cell wall and metal-ion complexation. (cea.fr)
- Considering the size and non-crystallinity of the sample, the obtained NMR spectra were of astonishing good resolution, allowing thus atom-resolved investigation of the peptidoglycan structure and dynamics. (cea.fr)
- In the actinobacterium Actinomyces oris , an LCP homolog here named LcpA is genetically linked to GspA, a glycoprotein that is covalently attached to the bacterial peptidoglycan by the housekeeping sortase SrtA. (asm.org)
- Recombination and the population structures of bacterial pathogens. (nih.gov)
- This is a Phase 3, multicenter, randomized, double-blind, parallel, comparative efficacy and safety study of single-dose IV oritavancin/IV placebo versus IV vancomycin for 7 to 10 days in adults with acute bacterial skin and skin structure infection (ABSSSI) suspected or proven to be caused by Gram-positive pathogens. (clinicaltrials.gov)
- Acute bacterial skin and skin-structure infections (ABSSSIs) continue to account for substantial morbidity and health care burden, with the emergence of drug-resistant pathogens further complicating their management. (the-hospitalist.org)
- Lots of pathogens produce these syringe structures that typically cause disease," Shikuma said. (scitechdaily.com)
- The mechanisms used by bacterial pathogens to regulate the expression of their genes, especially their virulence genes, have been the subject of intense investigation for several decades. (clinsci.org)
- At low surface area-to-volume ratios the diffusion of nutrients and waste products across the bacterial cell membrane limits the rate at which microbial metabolism can occur, making the cell less evolutionarily fit. (bionity.com)
- Bliska J, Cozzarelli N (1987) Use of site-specific recombination as a probe of DNA structure and metabolism in vivo. (springer.com)
- This volume is based on a FEMS Symposium entitled "Bacterial Growth and Lysis: Metabolism and Structure of the Bacterial Sacculus" held at the Monastery of Lluc (Mallorca, Spain) on 5-10 April, 1992. (booktopia.com.au)
- It has been suggested that ethanol metabolism in the strict anaerobe Clostridium kluyveri occurs within a metabolosome, a subcellular proteinaceous bacterial microcompartment. (biochemj.org)
- Molecular techniques were used to characterize bacterial community structure, diversity (16S rDNA), and activity (16S rRNA) in rhizospheres of three grain legumes: faba beans ( Vicia faba L., cv. (springer.com)
- However, the structure of the intact cap complex, and the molecular basis for its interaction with the filament, remains elusive. (nature.com)
- We also demonstrate that the native C. jejuni flagellum filament is 11-stranded, contrary to a previously published cryo-EM structure, and propose a molecular model for the filament-cap interaction. (nature.com)
- Structural and molecular mechanisms to produce these various mechanical properties of the axial structure, such as the filament, the hook, and the rod, have been revealed by the complementary use of X-ray crystallography and cryo-electron microscopy. (springer.com)
- In addition, the mechanism of growth of the axial structure is beginning to be revealed based on the molecular structure. (springer.com)
- Calladine CR (1978) Change of waveform in bacterial flagella: the role of mechanics at the molecular level. (springer.com)
- However, the molecular-level mechanisms, such as how ATP binding and hydrolysis change the ClpB structure and how the changes induce disaggregation, are not known. (technologynetworks.com)
- Reference: "Spatial structure in the "Plastisphere": Molecular resources for imaging microscopic communities on plastic marine debris" by Cathleen Schlundt, Jessica L. Mark Welch, Anna M. Knochel, Erik R. Zettler and Linda A. Amaral‐Zettler, 29 November 2019, Molecular Ecology Resources . (scitechdaily.com)
- The biomolecular structure-recognition relationship of the ligand-sensing leucine-rich repeat (LRR) domain of human NOD1 (NOD1-LRR) with PG DAP and PG DAPNH2 was studied by different computational techniques to further understand the molecular basis of our experimental observations. (portlandpress.com)
- Using molecular dynamics simulations of a comprehensive atomistic model cytoplasm we found that protein-protein interactions may destabilize native protein structures, whereas metabolite interactions may induce more compact states due to electrostatic screening. (elifesciences.org)
- In Italian rice fields, in particular, aspects from biogeochemistry to molecular ecology have been studied, but the impact of protistan grazing on the structure and function of the prokaryotic community has not been examined yet. (asm.org)
- Biochemist Maria Schumacher of the University of Texas M.D. Anderson Cancer Center has now determined the looplike structure of a molecular complex that is key to the distribution process. (marshallprotocol.com)
- Bacterial ATP synthases have been studied extensively because they are the simplest form of the enzyme and because of the relative ease of genetic manipulation of these complexes. (elifesciences.org)
- The structures reveal the path of transmembrane proton translocation and provide a model for understanding decades of biochemical analysis interrogating the roles of specific residues in the enzyme. (elifesciences.org)
- The 1.65 Å resolution crystal structure of the enzyme-adenylate complex reveals no unstructured loops or segments, and suggests that this enzyme binds the DNA without requiring full encirclement of the DNA duplex. (iucr.org)
- enzyme is the first structure available for the minimal type of bacterial DNA ligases and is the smallest DNA ligase to be crystallized to date. (iucr.org)
- When DNT (the inducer) appears in the bacterial cell it binds to an inducer-binding cavity in DntR, which results in the initiation of reading of a DNA segment (transcription) that codes for an enzyme that is involved in the digestion of DNT. (esrf.eu)
- We resampled the original 1994 soil transplants and controls, measuring CO 2 production, temperature response, enzyme activity, and bacterial community structure after 17 years. (osti.gov)
- Here we report the first structure of a cocaine-degrading enzyme. (whiterose.ac.uk)
- This study examines the structure of the active center of bacterial luciferase by exploiting the existence of two well-documented structural features of the (alpha) subunit of the enzyme, the essential cysteine and the protease-labile region, which are thought to reside there. (illinois.edu)
- The effects of climate change on soil organic matter-its structure, microbial community, carbon storage, and respiration response-remain uncertain and widely debated. (osti.gov)
- The impact of ocean acidification and carbonation on microbial community structure was assessed during a large-scale in situ costal pelagic mesocosm study, included as part of the EPOCA 2010 Arctic campaign. (biogeosciences.net)
- Understanding the drivers of phyllosphere bacterial diversity is the first step toward developing management strategies that encourage a healthy phyllosphere microbial community structure favoring tree health and function. (biomedcentral.com)
- The objective of this work was to evaluate the effect of influent pH on the hydrolytic acidification (HA) performance and microbial community structure in an expanded granular sludge bed (EGSB) pretreating crotonaldehyde manufacture wastewater (CMW) after ozonation. (iwaponline.com)
Acute Bacterial Skin7
- CTIX ) (the "Company"), a clinical stage biopharmaceutical company developing innovative therapies with oncology, dermatology, anti-inflammatory and antibiotic applications, is pleased to inform shareholders that laboratory testing of Brilacidin has been completed for use in the planned Phase 3 study in Acute Bacterial Skin and Skin Structure Infections (ABSSSI). (globenewswire.com)
- Allergan ) to include treatment of acute bacterial skin and skin structure infections (ABSSSI) in pediatric patients from birth to less than 2 months of age. (empr.com)
- PARIS, November 6 /PRNewswire/ -- Novexel, a speciality pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces today that its most advanced oral antibacterial NXL103 (flopristin/linopristin), has started a Phase II clinical trial in adults with acute bacterial skin and skin structure infections (ABSSSI). (science20.com)
- ABSSSI (Acute Bacterial Skin and Skin Structure Infections) are infections that involve deeper tissue or require surgical intervention (e.g. cellulitis, major cutaneous abscesses, and infected wounds) or are associated with a significant underlying disease that complicates response to therapy. (science20.com)
- Acute Bacterial Skin and Skin Structure Infections (ABSSSI) are the type of skin and soft tissue infections that affects the epidermis, dermis, and subcutaneous tissues. (coherentmarketinsights.com)
- The major market driver for growth of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) market is increasing research and development activities by pharmaceutical and biopharmaceutical companies to develop new products and novel treatment. (coherentmarketinsights.com)
- Acute bacterial skin and skin structure infections (ABSSSI) are a leading cause of hospitalization, but are often treated inappropriately in the inpatient setting. (figshare.com)
- Since the cell wall is required for bacterial survival, but is absent in some eukaryotes, several antibiotics (notably the penicillins and cephalosporins) stop bacterial infections by interfering with cell wall synthesis, while having no effects on human cells which have no cell wall, only a cell membrane. (wikipedia.org)
- For the six-month period of January to June 2010, a projected 9.2 million patients were treated in U.S. hospitals for infections of any type, and nearly 17 percent of the diagnostic category presentations were for skin and skin structure infections (SSSI). (cnbc.com)
- Increasing number of ambulatory patients seeking treatment for skin and skin structure infections will further propel growth of the ABSSSI market. (coherentmarketinsights.com)
- For instance, according to article published in 2015 of PLoS One journal, skin and skin structure infections related hospital admissions were 1.6% in 2005, increased to 2.0% in 2011. (coherentmarketinsights.com)
- The structure implies that substrates translocated from the cell interior through the transmembrane region and from the periplasm through the vestibules are collected in the central cavity and then actively transported through the pore into the TolC tunnel. (nih.gov)
- Interaction of surface-structured bacterial cellulose substrates with human fibroblasts and keratinocytes illustrates the efficient control of cellular activities which are fundamental in skin wound healing and tissue regeneration. (uzh.ch)
- The deployment of surface-structured bacterial cellulose substrates in model animals as skin wound dressing or body implant further proves the high durability and low inflammatory response to the material over a period of 21 days, demonstrating beneficial effects of surface structure on skin regeneration. (uzh.ch)
- The function of the bacterial microcompartment is to facilitate fermentation by sequestering the enzymes, substrates and intermediates. (biochemj.org)
- Although the three-dimensional structure of ClpB/Hsp104 has been determined by X-ray crystallography and cryo-electron microscopic single-particle analysis, information about the dynamics of individual molecules were required to understand the mechanism. (technologynetworks.com)
- Three-dimensional structure of CatD was determined by X-ray crystallography. (nii.ac.jp)
- To establish the structural framework underlying the Atm1 transport mechanism, we determined eight structures by X-ray crystallography and single-particle cryo-electron microscopy in distinct conformational states, stabilized by individual disulfide crosslinks and nucleotides. (pdbj.org)
- The structures of the two mutants were solved using X-ray crystallography and the orientation of the M265 side chain O-H, relative to the quinone, for the two mutants are in different orientations. (illinois.edu)
- The structures of M265IN and M265IQ were solved using X-ray crystallography. (illinois.edu)
- The structure of microbial communities colonizing microplastics collected from the North Atlantic Ocean (Vineyard Sound, Woods Hole, Mass.) This image reveals the phylogenetic affiliations of different bacterial groups. (scitechdaily.com)
- For the solid-state NMR study, uniformly 13 C- 15 N-isotopically enriched cells of different bacterial strains were grown, the sacculi purified and directly centrifuged into the NMR rotor. (cea.fr)
- Amplified 16S rDNA and rRNA products (using universal bacterial primers) were resolved by denaturing gradient gel electrophoresis (DGGE). (springer.com)
- Bacterial community diversity and structure were studied by sequencing of 16S rRNA gene clone libraries. (springer.com)
- While the temperature treatment rapidly impacted the photophysiology of the coral host, it did not elicit a statistically significant shift in bacterial community structure from control, untreated corals as determined by terminal restriction fragment length polymorphism analysis of 16S rRNA genes. (hindawi.com)
- Analysis of bacterial taxa via 16S rRNA gene sequencing showed changes in community structure through time following the sewage spill in sediment and water. (asm.org)
- This study evaluated soil microbiological functioning (SMF), richness, diversity, and structure of bacterial communities from two ultramafic soils and from a non-ultramafic soil in the Brazilian Cerrado, a tropical savanna. (springer.com)
- We believe this work presents benchmark information on SMF, diversity, and structure of bacterial communities for a unique type of environment within the Cerrado biome. (springer.com)
- In this study, the integrated effect of seasonal differences and spatial distribution on bacterial community structure and diversity were investigated at the regional scale. (frontiersin.org)
- Sequence diversity within a family of functional enzymes provides a platform for elucidating structure-function relationships and for protein engineering to improve properties important for applications. (caltech.edu)
- Our work illustrates the role that structure-guided recombination can play in helping to identify sequence-function relationships within a family of enzymes by supplementing natural diversity with synthetic diversity. (caltech.edu)
- The bacterial diversity detectable by T-RFLP analysis was greater in the presence of protists. (asm.org)
- however, shifts in bacterial community diversity were observed in bioassays amended with either P or NP. (mcmlter.org)
- We suggest that climate-associated increases in phytoplankton production and concomitant shifts in diversity will influence MDV bacterial community structure by altering the availability and composition of autochthonous carbon for heterotrophic production. (mcmlter.org)
- The results showed that the bacterial community diversity in the cultivated C. sachalinensis rhizosphere was always higher than the wild, while the evenness and dominance indices followed a different pattern as compared to band richness in the wild and cultivated conditions. (ajol.info)
- The pocket structure is sustained by interactions between the catalytic domain and the RNA-binding domain. (rcsb.org)
- This brief review will focus primarily on the last two descriptions, i.e., the two- and three- dimensional structures and their stabilizing protein-DNA interactions. (springer.com)
- Spatially, the Plastisphere microbial communities were heterogeneously mixed, providing the first glimpse of bacterial interactions on marine microplastics. (scitechdaily.com)
- From this perspective, homologous protein structures within the same functional classification should reveal a constant rate of structural drift relative to sequence changes. (nih.gov)
- As expected, the analysis demonstrates a sharp structural divergence between the bacterial phyla Firmicutes and Proteobacteria. (nih.gov)
- Additionally, each COG had a distinct sequence/structure relationship, indicating that different evolutionary pressures affect the degree of structural divergence. (nih.gov)
- On the other hand, the major structural differences between the Firmicutes and Proteobacteria are highlighted in red on a representative Firmicutes (C) structure from L. plantarum ( Lpl ) (PDB ID: 1POW) (Muller et al. (nih.gov)
- A comparison of the EcPAP structure with those of other template-independent RNA polymerases suggests that structural changes of domain(s) outside the conserved catalytic core domain altered the substrate specificities of the template-independent RNA polymerases. (rcsb.org)
- As in other organisms, the bacterial cell wall provides structural integrity to the cell. (bionity.com)
- The structure suggests a unique photochemical signaling switch in which the absorption of light induces a structural change in the rim surrounding the hook, thereby changing the protein interface between BLUF and the output domain. (pnas.org)
- I- Ceu I mapping revealed virtually indistinguishable genome structures, demonstrating a high degree of structural conservation. (asm.org)
- In a fundamental step towards understanding the structure/function relationships within the family we have used small-angle neutron scattering (SANS) on two distantly related bacterial homologues to show that there is a common, dimeric and structural architecture among Slc26A transporters. (sigmaaldrich.com)
- We regret the loss of this outstanding structural microbiologist who made stellar contributions to varied topics such as the structure of the S-layer, the interaction of microbial surfaces with metals and antibiotics, bacterial cell division, Gram stain and its variability, and many more. (asmblog.org)
- In the project "Structure-function relationship in bacterial adhesins(BACTAD)", we try to elucidate the structural basis for bacterial adhesion. (uio.no)
- We propose to build on our preliminary work to develop a novel pipeline for the structural analysis of bacterial PG, combining ultra-high resolution LC-MS/MS with the Byos software platform from Protein Metrics. (findaphd.com)
- Specifically, these scientists used a battery of structural, biophysical, biochemical, and genetic experiments to decipher and understand the structure and function of the UvrA-UvrB DNA damage sensor. (harvard.edu)
- A structural framework for unidirectional transport by a bacterial ABC exporter. (pdbj.org)
- Here we report the structure of the trimeric bacterial microcompartment protein EtuB, which has a tandem structural repeat within the subunit and pseudo-hexagonal symmetry. (biochemj.org)
- Thus, structural properties of eukaryotic voltage-gated sodium channels, which are implied by functional data, were reproduced in the NavAb-based models built using the unaltered template structure, but adjusted sequence alignment. (aspetjournals.org)
- Solution NMR structure of Lin0431 protein from Listeria innocua reveals high structural similarity with domain II of bacterial transcription antitermination protein NusG. (rostlab.org)
- The existence of clones within bacterial populations, and of linkage disequilibrium between alleles at different loci, is often cited as evidence for low rates of recombination. (nih.gov)
- Moreover, the differences in dynamics between spatially structured and mixed populations are poorly understood. (uidaho.edu)
- We suggest that, if cheats reduce colony size, thus self-limiting their global population, microcolony-based group structures may be an important (potentially evolved) mechanism to suppress cheats in bacterial populations. (soton.ac.uk)
- Such physiologically structured populations typically consist of subpopulations of cells in different metabolic and regulatory states. (ovid.com)
- En utilisant la même approche, il a été possible de distinguer les sous-populations même si leurs tailles se chevauchaient. (ovid.com)
- Les valeurs de distribution de la taille des cellules ont aussi été utilisées, partiellement en association avec la microscopie en fluorescence, pour mesurer la dynamique des populations de Pseudomonas fluorescens et de Nitrosomonas europaea lors d'une récupération d'une perte d'énergie. (ovid.com)
- It has been widely assumed that the atomic structure of the flagellar filament from Salmonella typhimurium serves as a model for all bacterial flagellar filaments given the sequence conservation in the coiled-coil regions responsible for polymerization. (sciencemag.org)
- Fujii T, Kato T, Hiraoka KD, Miyata T, Minamino T, Chevance FF, Hughes KT, Namba K (2017) Identical folds used for distinct mechanical functions of the bacterial flagellar rod and hook. (springer.com)
- Fujii T, Kato T, Namba K (2009) Specific arrangement of alpha-helical coiled coils in the core domain of the bacterial flagellar hook for the universal joint function. (springer.com)
- The three-dimensional structure of a complex of MotA and the flagellar motor structure in a bacterial cell. (researchsea.com)
- Bacterial nano-cellulose (BNC) is a well-known biocompatible material with enormous water-holding capacity. (mdpi.com)
- Obtained results confirm that a genetic modification of productive bacterial strain is a plausible way of adjustment of bacterial cellulose properties for tissue engineering applications without the employment of any chemical modifications. (mdpi.com)
- Jacek P, Szustak M, Kubiak K, Gendaszewska-Darmach E, Ludwicka K, Bielecki S. Scaffolds for Chondrogenic Cells Cultivation Prepared from Bacterial Cellulose with Relaxed Fibers Structure Induced Genetically. (mdpi.com)
- Crystalline cellulose microfibrils are embedded in wall matrix polymers and assembled into hierarchical structures that are precisely designed for specific biological and mechanical functions. (rsc.org)
- The comparison of vibrational SFG spectra of uniaxially-aligned and disordered films of cellulose Iβ nanocrystals revealed that the spectral features cannot be fully explained with the crystallographic unit structure of cellulose. (rsc.org)
- It was also found that the OH SFG stretch peaks could be deconvoluted to find the polymorphic crystal structures of cellulose (Iα and Iβ). (rsc.org)
- These findings were used to investigate the cellulose crystal structure and mesoscale cellulose microfibril packing in intact plant cell walls, tunicate tests, and bacterial films. (rsc.org)
- A powerful replica molding methodology to transfer on-demand functional topographies to the surface of bacterial cellulose nanofiber textures is presented. (uzh.ch)
- Upon bacterial fermentation, the generated bacterial cellulose nanofibers are assembled in a three-dimensional network reproducing the geometric shape imposed by the mold. (uzh.ch)
- Goldstein E, Drlica K (1984) Regulation of bacterial DNA supercoiling: Plasmid linking numbers vary with growth temperature. (springer.com)
- It is not known if or how plasmids persist in and spread through (invade) a bacterial population when there is no selection for plasmid-encoded traits. (uidaho.edu)
- Using protocols that differed in degree of spatial structure and nutrient levels, the invasiveness of plasmid pB10 in E. coli was monitored during at least 15 days, with an initial fraction of plasmid-bearing (p+) cells as low as 1E-7. (uidaho.edu)
- What a wonderfull representation of the bacterial plasmid. (marshallprotocol.com)
- We examined the impact of 17 years of land management on soil bacterial communities in a New Zealand randomized-block pasture trial. (wiley.com)
- Changes in soil chemistry and legume abundance described 52% of the observed variation in the bacterial community structure. (wiley.com)
- 11% of the variation in soil bacterial community structure was attributed to this shift in the plant community. (wiley.com)
- Our results suggest that removal of plant biomass and associated phosphorus, as well as shifts in the plant community, have greater long-term impacts on soil bacterial community structure than application of nitrogen fertilizers. (wiley.com)
- We compared an untreated control soil with a γ-radiation-sterilized soil that had been reinoculated with a natural bacterial assemblage. (asm.org)
- Increased abundance of total and Acidobacterial lineages in low As-containing soil and the detection of several uncultured groups among nifH gene sequence in higher frequency indicated the presence of novel nifH bearing bacterial groups. (deepdyve.com)
- Examination of the packing between molecules in the crystals reveals the structure of a homotetramer in which the inducer-binding domains of DntR adopt a 'head-tail-head-tail' arrangement, similar to that recently reported for CbnR  , which belongs to the same family of transcriptional regulators (LysR) as DntR and is the only other full-length transcription factor that has been crystallised. (esrf.eu)
- They found that it can form a structure of four MotA molecules (called a tetramer), which differs in shape from the previously predicted complex. (researchsea.com)
- When bacterial cells divide, small DNA molecules called plasmids that encode antibiotic resistance genes are distributed into the two resulting daughter cells. (marshallprotocol.com)
- In addition, the effects of climate changes on ecosystem structure and function are often modulated or delayed, meaning that short-term experiments are not sufficient to characterize ecosystem responses. (osti.gov)
- Since most knowledge of tree phyllosphere bacterial communities has been gathered in tropical forests, our goal was to characterize the community structure and assembly dynamics of phyllosphere epiphytic bacterial communities in temperate forests in Quebec, Canada. (biomedcentral.com)
Types of bacterial1
- There are two main types of bacterial cell walls, Gram positive and Gram negative, which are differentiated by their Gram staining characteristics. (bionity.com)
- The protein structures for COG0028 thiamine pyrophosphate requiring enzymes show (A) that the two Firmicutes structures have highly overlapping structures and (B) that the four Proteobacteria structures are very similar to each another. (nih.gov)
- Baxdela exerts antibacterial activity through inhibition of both bacterial topoisomerase IV and DNA gyrase (topoisomerase II) enzymes needed for bacterial DNA replication, transcription, repair, and recombination. (empr.com)
- Bacterial Adhesion - Chemistry, Biology and Physics. (uio.no)
- Here we present the 2.3 Å structure of a functional urea transporter from the bacterium Desulfovibrio vulgaris . (nature.com)
- The bacterium, despite its simplicity, contains a well-developed cell structure which is responsible for some of its unique biological structures and pathogenicity. (wikipedia.org)
- Here, the structure and activity of a recombinantly produced ATP-dependent DNA ligase from the bacterium Psychromonas sp. (iucr.org)
- Here, we show that a marine bacterium, Pseudoalteromonas luteoviolacea, produces arrays of phage tail-like structures that trigger metamorphosis of H. elegans. (caltech.edu)
- A team of Japanese researchers led by Homma's laboratory of Nagoya University have now purified the stator protein MotA from a bacterium found in hot springs (Aquifex aeolicus) and analyzed its three-dimensional structure using electron microscopy mainly in cooperation with Namba's laboratory of Osaka University. (researchsea.com)
- By examining this bacterium that causes metamorphosis in the humble tubeworm, marine microbiologists at SDSU discovered that the nanoscale syringe-like structures produced by it - a structure nicknamed the Death Star for the effect it has - could be used in the future to deliver novel therapeutics or vaccines to targeted cells and tissues in humans. (scitechdaily.com)
- Shikuma discovered that the bacterium has Metamorphosis Associated Contractile structures (MACs) - syringe-like structures that inject content into the larvae of tubeworms, helping transform it into juvenile worms. (scitechdaily.com)
- Shikuma's lab used cryo-electron tomography imaging to study the structures and found arrays of death star-shaped injection systems, which are released by the bacterium. (scitechdaily.com)
- Comparison of a typical bacterial cell and a typical human cell (assuming both cells are spheres) : The cell envelope is composed of the cell membrane and the cell wall. (wikipedia.org)
- The architecture of the membrane region shows how the simple bacterial ATP synthase is able to perform the same core functions as the equivalent, but more complicated, mitochondrial complex. (elifesciences.org)
- The filamentous part that extends from the cell membrane is called the axial structure and consists of three major parts, the filament, hook, and rod, and other minor components. (springer.com)
- The MotA protein spans the bacterial membrane, and has previously been shown to form a tetramer complex with another transmembrane protein, MotB, creating the stator. (researchsea.com)
- One indication of these fluctuations in three-dimensional structure is that the shape of the bacterial nucleoid is irregular and varies in different cells in the same culture. (springer.com)
- Bjornsti M-A, Hobot JA, Kelus AS, Villiger W, Kellenberger E (1986) New electron microscopic data on the structure of the nucleoid and their functional consequences. (springer.com)
- Plant-dependent rhizosphere effects were evident from significant differences in the bacterial community structure of the legume rhizospheres under study. (springer.com)
- Phylogeny-based methods detected qualitative and quantitative differences in pairwise comparisons of bacterial community structures of the three sites. (springer.com)
- However, no correlations between community structure differences and SOM or SMF were detected. (springer.com)
- Slight differences in local climate between the upper and lower Rattlesnake locations, simulated with environmental control chambers during the incubation, thus prompted significant differences in microbial activity, with no observed change to bacterial structure. (osti.gov)
- In the present study, NOD1 stimulation assays were performed using bacterial PG containing meso DAP (PG DAP ) and meso DAP NH2 (PG DAPNH2 ) to understand the differences in their biomolecular recognition mechanism. (portlandpress.com)
- In spite of the importance of plasmids in bacterial adaptation we have a poor understanding of their dynamics. (uidaho.edu)
- The increasing awareness of the role of phyllosphere microbial communities in plant health calls for a greater understanding of their structure and dynamics in natural ecosystems. (biomedcentral.com)
- Temporal dynamics of total and free-living nitrogen-fixing bacterial community abundance and. (deepdyve.com)
- Herein, our study demonstrated that the dynamics of free-living nitrogen-fixing bacterial communities were perturbed due to As contamination in agricultural land. (deepdyve.com)
- Maybe it's because basil is great anti-bacterial! (bioelectricshield.com)
- Comparing the total bacterial profiles with actinomycete-specific ones (using actinomycete-specific primers) highlighted the dominance of this group in the three rhizospheres. (springer.com)
- This mini-review describes our present understanding of the structure and function of the purple bacterial light-harvesting complexes. (gla.ac.uk)
- We present the high resolution crystal structure of the dark resting state of BlrB, a short BLUF domain-containing protein from Rhodobacter sphaeroides . (pnas.org)
- We have determined the crystal structure of AcrB at 3.5 A resolution. (nih.gov)
- Here we report the crystal structure at 2.8 A resolution of recombinant FtsZ from the hyperthermophilic methanogen Methanococcus jannaschii. (nih.gov)
- The crystal structure of cocE, solved by multiple anomalous dispersion (MAD) methods, reveals that cocE is a serine esterase composed of three domains: (i) a canonical alpha/beta hydrolase fold (ii) an alpha-helical domain that caps the active site and (iii) a jelly-roll-like beta-domain that interacts extensively with the other two domains. (whiterose.ac.uk)
- Crystal structure of the bacterial luciferase/flavin complex provides insight into the function of the beta subunit. (sigmaaldrich.com)
- We report here the crystal structure of V. harveyi luciferase bound to flavin mononucleotide (FMN) at 2.3 A. The isoalloxazine ring is coordinated by an unusual cis-Ala-Ala peptide bond. (sigmaaldrich.com)
- The HrcQ(B) protein, a component of the secretion apparatus of Pseudomonas syringae with homologues in all type III systems, has a variable N-terminal and a conserved C-terminal domain (HrcQ(B)-C). Here, we report the crystal structure of HrcQ(B)-C and show that this domain retains the ability of the full-length protein to interact with other type III components. (whiterose.ac.uk)
- We have determined the crystal structure of the McpX periplasmic region (McpX PR ) in complex with the proline betaine at 2.7 Å resolution. (biochemj.org)
- Compared to their mitochondrial counterparts, bacterial ATP synthases have a simpler subunit composition. (elifesciences.org)
- Bacterial luciferase from Vibrio harveyi is a heterodimer composed of a catalytic alpha subunit and a homologous but noncatalytic beta subunit. (sigmaaldrich.com)
- Within this portion of the protein, a single contact was observed between Phe272 of the alpha subunit, not seen in the previous structures, and Tyr151 of the beta subunit. (sigmaaldrich.com)
- The physical structure of bacterial genomes as revealed by endonuclease mapping, on the other hand, could provide an alternative parameter to be employed in phylogenetic studies ( 26 , 29 ). (asm.org)
- We will explore the natural variation in PG structure in Clostridium difficile. (findaphd.com)
- Two of three coral colonies harbored more closely related bacterial communities at the time of collection and, despite statistically significant shifts in bacterial community structure for both control and treatment corals during the 10-day acclimation period, maintained this relationship over the course of the experiment. (hindawi.com)
- Phys.org)-The latest in super-resolution microscope technology has allowed Australian researchers rewrite the book on the process of bacterial cell division, potentially opening the door to new kinds of antibiotics. (phys.org)
- Tip of the Day: These particular bacterial are very now very resistant to commonly used antibiotics. (bioelectricshield.com)
- PG structure in circulating clinical strains will be analysed to determine how this relates to the spectrum of resistance to beta-lactam antibiotics. (findaphd.com)
- NXL103, as a member of the Streptogramin class of antibiotics, has a unique mode of action, with its two components acting synergistically to inhibit the bacterial ribosome. (science20.com)
- Unique to the bacterial world, this large polymer network is also the principal target of many antibiotics, and one of the main microbial products recognized by the immune system. (cea.fr)
- These findings provide experimental and modeling evidence for a class of communities that require microscale spatial structure for stability, and these results predict that controlling spatial structure may enable harnessing the function of natural and synthetic multispecies communities in the laboratory. (pnas.org)
- The bacterial protein Recombinase A (RecA) may be able to provide this function. (bl.uk)
- For her master thesis at Freie Universität Berlin and the MX beamlines of BESSY II, she deciphered the structure and function of a so-called RNA helicase. (helmholtz-berlin.de)
- Publications] M. Hashimoto 他: 'Structure and function of the domains composing chitinase Al of Bacillus circulans WL-12'Cellulose Degradation (Proceeding of MIE BIOFORUM 98). (nii.ac.jp)
- In nature, microbial communities inhabit matrices with intricate spatial structure ( 6 , 7 ). (pnas.org)
- Furthermore, microscale spatial structure has not been controlled and varied experimentally to understand its effect on the stability of bacterial communities. (pnas.org)
- The bathymetry of the Scotian Shelf, the abrupt shelf break to the Scotian Slope and the major ocean currents dominating in the region led to the formation of distinct on-shelf and off-shelf bacterial communities both in spring and fall. (frontiersin.org)
- Now, using an innovative microscopy method developed at the Marine Biological Laboratory (MBL), Woods Hole, scientists have revealed the structure of the microbial communities coating microplastic samples from a variety of ocean sites. (scitechdaily.com)
- The main variables structuring these communities were sample origins (fjord or mesocosms) and the community size fraction (small or large size fraction). (biogeosciences.net)
- This spatial structure has been hypothesized to be important in microbial ecology ( 10 - 13 ). (pnas.org)
- However, on this small scale spatial structure is difficult to control in natural environments. (pnas.org)
- In conclusion, spatial structure and nutrient availability can be key determinants in the invasiveness of plasmids. (uidaho.edu)
- We now have a toolkit that enables us to understand the spatial structure of the Plastisphere and, combined with other methods, a better future way to understand the Plastisphere's major microbial players, what they are doing, and their impact on the fate of plastic litter in the ocean," said Amaral-Zettler, a MBL Fellow from the NIOZ Royal Netherlands Institute for Sea Research and the University of Amsterdam. (scitechdaily.com)
- Teflaro, a cephalosporin antibiotic, is also indicated for the treatment of community-acquired bacterial pneumonia (CABP). (empr.com)
- This relationship existed despite the statistically significant difference in community structure between the free-living and particle-associated size fractions. (frontiersin.org)
- Previous article in issue: Pseudomonad replication origins: a paradigm for bacterial origins? (wiley.com)
- In this MicroReview we compare first the structures of these DnaA-box regions and their locations on the chromosome and then functional aspects of DnaA protein and DnaA-box regions in the initiation and regulation of chromosomal replication. (wiley.com)
- Comprehensive reviews on bacterial S- layers and yeast cell walls are included to stimulate conceptual cross-feeding with these closely related topics. (booktopia.com.au)
- Broyles S, Pettijohn D (1986) Interaction of the Escherichia coli HU protein with DNA: evidence for formation of nucleosome-like structures with altered DNA helical pitch. (springer.com)
- The first part of this work describes studies on the structures of three bacterial polysaccharides, i.e., the extracellular polysaccharides of Streptococcus pneumoniae type 2 and Butyrivibrio fibrisolvens strain X6C61 and the O-antigenic side-chain of the lipopolysaccharide of Escherichia coli 086. (diva-portal.org)
- DePamphilis ML, Adler J (1971b) Fine structure and isolation of the hook-basal body complex of flagella from Escherichia coli and Bacillus subtilis . (springer.com)
- High level expression system of ChBD in E. coli was constructed and its structure and properties were studied. (nii.ac.jp)
- We aim to use the Mesolens to image the previously unexplored internal architecture of an intact Escherichia coli colony biofilm to better understand spatiotemporal organisation of a live bacterial community. (strath.ac.uk)
- It has been proposed that the chemical composition of a coral's mucus can influence the associated bacterial community. (frontiersin.org)
- This study therefore compared the carbohydrate composition of mucus in the coral Acropora muricata when subjected to increasing thermal stress from 26 to 31¼C, and determined whether this composition correlated with any changes in the bacterial community. (frontiersin.org)
- Changes in mucus composition and the bacterial community in the mucus layer occurred at 29¼C, which were prior to visual signs of coral bleaching at 31¼C. (frontiersin.org)
- The bacterial community structures of the Cerasus sachalinensis Kom. (ajol.info)