Infections by bacteria, general or unspecified.
Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.
Infections with bacteria of the genus LISTERIA.
Substances that reduce the growth or reproduction of BACTERIA.
Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyroid cells and acts to decrease the formation and absorptive activity of osteoclasts. Its role in regulating plasma calcium is much greater in children and in certain diseases than in normal adults.
The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
A species of gram-positive, rod-shaped bacteria widely distributed in nature. It has been isolated from sewage, soil, silage, and from feces of healthy animals and man. Infection with this bacterium leads to encephalitis, meningitis, endocarditis, and abortion.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
A general term for diseases produced by viruses.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Inflammation of the lung parenchyma that is caused by bacterial infections.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Infections with bacteria of the species ESCHERICHIA COLI.
Infections caused by bacteria and fungi, general, specified, or unspecified.
Infections with bacteria of the genus PSEUDOMONAS.
Infections with bacteria of the genus STAPHYLOCOCCUS.
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Skin diseases caused by bacteria.
The interactions between a host and a pathogen, usually resulting in disease.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Bacteria which retain the crystal violet stain when treated by Gram's method.
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
A species of gram-negative bacteria in the genus CITROBACTER, family ENTEROBACTERIACEAE. As an important pathogen of laboratory mice, it serves as a model for investigating epithelial hyperproliferation and tumor promotion. It was previously considered a strain of CITROBACTER FREUNDII.
Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.
Infections with bacteria of the genus STREPTOCOCCUS.
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts with multiple ligands including PEPTIDOGLYCAN, bacterial LIPOPROTEINS, lipoarabinomannan, and a variety of PORINS.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Infections with bacteria of the genus KLEBSIELLA.
Measurable quantity of bacteria in an object, organism, or organism compartment.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
Fever in which the etiology cannot be ascertained.
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.
Infections with bacteria of the family ENTEROBACTERIACEAE.
The hairs which project from the edges of the EYELIDS.
Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia.
A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.
A decrease in the number of NEUTROPHILS found in the blood.
Infections with bacteria of the genus HAEMOPHILUS.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Infection of the lung often accompanied by inflammation.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.
Infections in animals with bacteria of the genus SALMONELLA.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Infections with bacteria of the genus SALMONELLA.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
Infections in the inner or external eye caused by microorganisms belonging to several families of bacteria. Some of the more common genera found are Haemophilus, Neisseria, Staphylococcus, Streptococcus, and Chlamydia.
Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral.
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.
An infant during the first month after birth.
Disease having a short and relatively severe course.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
Elements of limited time intervals, contributing to particular results or situations.
Peptidoglycan immunoadjuvant originally isolated from bacterial cell wall fragments; also acts as pyrogen and may cause arthritis; stimulates both humoral and cellular immunity.
An encapsulated lymphatic organ through which venous blood filters.
Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.
Invasion of the site of trauma by pathogenic microorganisms.
DEFENSINS found mainly in epithelial cells.
Skin diseases caused by bacteria, fungi, parasites, or viruses.
Proteins found in any species of bacterium.
Simultaneous infection of a host organism by two or more pathogens. In virology, coinfection commonly refers to simultaneous infection of a single cell by two or more different viruses.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).
Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications.
INFLAMMATION of the BREAST, or MAMMARY GLAND.
Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Diseases affecting the orderly growth and persistence of hair.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The natural bactericidal property of BLOOD due to normally occurring antibacterial substances such as beta lysin, leukin, etc. This activity needs to be distinguished from the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy, which is measured by a SERUM BACTERICIDAL TEST.
The diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions.
Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.
A frequent complication of drug therapy for microbial infection. It may result from opportunistic colonization following immunosuppression by the primary pathogen and can be influenced by the time interval between infections, microbial physiology, or host resistance. Experimental challenge and in vitro models are sometimes used in virulence and infectivity studies.
Pathological processes involving any part of the UTERUS.
Substances elaborated by bacteria that have antigenic activity.
Cells that can carry out the process of PHAGOCYTOSIS.
Inflammation of the lung parenchyma that is caused by a viral infection.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Established cell cultures that have the potential to propagate indefinitely.
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Any blood or formed element especially in invertebrates.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection.
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances.
A species of gram-positive, spherical bacteria whose organisms occur in tetrads and in irregular clusters of tetrads. The primary habitat is mammalian skin.
A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
A bile salt formed in the liver by conjugation of deoxycholate with glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and choleretic.
Strains of Escherichia coli that preferentially grow and persist within the urinary tract. They exhibit certain virulence factors and strategies that cause urinary tract infections.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that causes rotting, particularly of storage tissues, of a wide variety of plants and causes a vascular disease in CARROTS; and POTATO plants.
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
A broad-spectrum antimicrobial carboxyfluoroquinoline.
Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction.
A species of the genus YERSINIA, isolated from both man and animal. It is a frequent cause of bacterial gastroenteritis in children.
Infections with bacteria of the genus YERSINIA.
Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).
A bacterium which causes mastitis in cattle and occasionally in man.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.
A disease of humans and animals that resembles GLANDERS. It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia.
Infections or infestations with parasitic organisms. They are often contracted through contact with an intermediate vector, but may occur as the result of direct exposure.
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Proteins that bind to particles and cells to increase susceptibility to PHAGOCYTOSIS, especially ANTIBODIES bound to EPITOPES that attach to FC RECEPTORS. COMPLEMENT C3B may also participate.
Glycolipid-anchored membrane glycoproteins expressed on cells of the myelomonocyte lineage including monocytes, macrophages, and some granulocytes. They function as receptors for the complex of lipopolysaccharide (LPS) and LPS-binding protein.
Infections with bacteria of the genus SERRATIA.
Glycoproteins found on the membrane or surface of cells.
The passage of viable bacteria from the GASTROINTESTINAL TRACT to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the INTESTINAL MUCOSA resulting in increased intestinal permeability. Bacterial translocation from the lung to the circulation is also possible and sometimes accompanies MECHANICAL VENTILATION.
An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood.
Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Mononuclear phagocytes derived from bone marrow precursors but resident in the peritoneum.
The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants.
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.
A disease of the eye in which the eyelashes abnormally turn inwards toward the eyeball producing constant irritation caused by motion of the lids.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis.
A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.
Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.
A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.
Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. They are used to treat a variety of diseases associated with decreased or abnormal immunoglobulin levels including pediatric AIDS; primary HYPERGAMMAGLOBULINEMIA; SCID; CYTOMEGALOVIRUS infections in transplant recipients, LYMPHOCYTIC LEUKEMIA, CHRONIC; Kawasaki syndrome, infection in neonates, and IDIOPATHIC THROMBOCYTOPENIC PURPURA.
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.
A chronic infection of the CONJUNCTIVA and CORNEA caused by CHLAMYDIA TRACHOMATIS.
A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.
The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are thought to play a role in host defenses against infections, inflammation, wound repair, and acquired immunity.
A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that utilizes citrate as a sole carbon source. It is pathogenic for humans, causing enteric fevers, gastroenteritis, and bacteremia. Food poisoning is the most common clinical manifestation. Organisms within this genus are separated on the basis of antigenic characteristics, sugar fermentation patterns, and bacteriophage susceptibility.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
Virus diseases caused by the ORTHOMYXOVIRIDAE.
This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.
Inflammation of the cornea.
A species of gram-negative bacteria in the genus ACTINOBACILLUS. It is mainly a pathogen of PIGS, but also can infect HORSES.
A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
A species of STAPHYLOCOCCUS that is a spherical, non-motile, gram-positive, chemoorganotrophic, facultative anaerobe. Mainly found on the skin and mucous membrane of warm-blooded animals, it can be primary pathogen or secondary invader.
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
A large increase in oxygen uptake by neutrophils and most types of tissue macrophages through activation of an NADPH-cytochrome b-dependent oxidase that reduces oxygen to a superoxide. Individuals with an inherited defect in which the oxidase that reduces oxygen to superoxide is decreased or absent (GRANULOMATOUS DISEASE, CHRONIC) often die as a result of recurrent bacterial infections.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
A secreted protein that associates with TOLL-LIKE RECEPTOR 4 and is essential for receptor recognition of LIPOPOLYSACCHARIDES.
Physiological processes and properties of BACTERIA.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Experimental production of infectious bovine keratoconjunctivitis: comparison of serological and immunological responses using pili fractions of Moraxella bovis. (1/6004)

The effect of vaccinating cattle and mice on the development of keratoconjunctivitis was studied. Cattle were vaccinated with whole cells, disrupted cells and pili fractions of three strains of Moraxella bovis. Mice were vaccinated with pili fractions of three strains. The resistance of all vaccinated animals was challenged with virulent cultures of M. bovis. In an attempt to correlate the response seen after vaccination and challenge with a pili fraction of M. bovis, vaccinated cattle and mice were grouped on the basis of signs of disease manifested and compared on the basis of serological responses. Serum samples were tested for antibodies by a gel diffusion precipitin test. A greater number of the sera of resistant cattle had antibodies to the homologous pili antigen than those of vaccinated nonresistant cattle. Cattle vaccinated with disrupted cells were not resistant to infectious bovine kerato-conjuctivitis and their sera lacked antibodies against the pili antigens. Vaccinated mice were more resistant to infectious bovine kerato-conjuctivitis and their sera lacked antibodies against the pili antigens. Vaccinated mice were more resistant to challenge exposure by homologous than heterologous cultures. A greater number of the sera of resistant mice had antibodies to pili antigens than nonresistant mice.  (+info)

Clindamycin plus gentamicin as expectant therapy for presumed mixed infections. (2/6004)

The prevalence of obligate anaerobes was studied prospectively in 60 patients with severe sepsis of intra-abdominal, soft tissue, female genital or oropulmonary origin. In addition, the efficacy of clindamycin (for anaerobes) plus gentamicin (for aerobic bacteria, especially coliforms) as initial empiric therapy in these patients was evaluated. Among 54 patients with cultural proof of infection, anaerobic pathogens were recovered from 52%. Nineteen patients had bacteremia; Bacteroides fragilis and Klebsiella pneumoniae were the most prevalent pathogens, being isolated in five patients each. Infection was eradicated in 56 of the 60 patients (93%). Mortality related to sepsis was 7% in the entire group, 16% in patients with bacteremia and 2% in patients without bacteremia. Eighty-five percent of aerobic isolates tested were susceptible in vitro to either gentamicin or clindamycin; 97% of anaerobic isolates were inhibited by 5 mug/ml of clindamycin.  (+info)

Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. (3/6004)

The two genetically established antimicrobial mechanisms of macrophages are production of reactive oxygen intermediates by phagocyte oxidase (phox) and reactive nitrogen intermediates by inducible nitric oxide synthase (NOS2). Mice doubly deficient in both enzymes (gp91(phox-/-)/NOS2(-/-)) formed massive abscesses containing commensal organisms, mostly enteric bacteria, even when reared under specific pathogen-free conditions with antibiotics. Neither parental strain showed such infections. Thus, phox and NOS2 appear to compensate for each other's deficiency in providing resistance to indigenous bacteria, and no other pathway does so fully. Macrophages from gp91(phox-/-)/NOS2(-/-) mice could not kill virulent Listeria. Their killing of S. typhimurium, E. coli, and attenuated Listeria was markedly diminished but demonstrable, establishing the existence of a mechanism of macrophage antibacterial activity independent of phox and NOS2.  (+info)

Receptor clearance obscures the magnitude of granulocyte-macrophage colony-stimulating factor responses in mice to endotoxin or local infections. (4/6004)

Marrow cells from mice lacking high-affinity receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF; betac-/- mice) were shown to bind and internalize much less GM-CSF than cells from normal (betac+/+) mice. betac-/- mice were used to determine the effect of negligible receptor-mediated clearance on detectible GM-CSF responses to the intravenous injection of endotoxin or the intraperitoneal injection of casein plus microorganisms. Unlike the minor serum GM-CSF responses to endotoxin seen in betac+/+ mice, serum GM-CSF levels rose 30-fold to 9 ng/mL in betac-/- mice even though loss of GM-CSF in the urine was greater than in betac+/+ mice. Organs from betac-/- and betac+/+ mice had a similar capacity to produce GM-CSF in vitro, as did peritoneal cells from both types of mice when challenged in vitro by casein. However, when casein was injected intraperitoneally, betac-/- mice developed higher and more sustained levels of GM-CSF than did betac+/+ mice. The data indicated that receptor-dependent removal of GM-CSF masks the magnitude of GM-CSF responses to endotoxin and local infections. Because of this phenomenon, serum GM-CSF concentrations can be a misleading index of the occurrence or nonoccurrence of GM-CSF responses to infections.  (+info)

In vivo activities of peptidic prodrugs of novel aminomethyl tetrahydrofuranyl-1 beta-methylcarbapenems. (5/6004)

A series of novel aminomethyl tetrahydrofuranyl (THF)-1 beta-methylcarbapenems which have excellent broad-spectrum antibacterial activities exhibit modest efficacies against acute lethal infections (3.8 mg/kg of body weight against Escherichia coli and 0.9 mg/kg against Staphylococcus aureus) in mice when they are administered orally. In an effort to improve the efficacies of orally administered drugs through enhanced absorption by making use of a peptide-mediated transport system, several different amino acids were added at the aminomethyl THF side chains of the carbapenem molecules. The resulting peptidic prodrugs with L-amino acids demonstrated improved efficacy after oral administration, while the D forms were less active than the parent molecules. After oral administration increased (3 to 10 times) efficacy was exhibited with the alanine-, valine-, isoleucine-, and phenylalanine-substituted prodrugs against acute lethal infections in mice. Median effective doses (ED50s) of < 1 mg/kg against infections caused by S. aureus, E. coli, Enterobacter cloacae, or penicillin-susceptible Streptococcus pneumoniae were obtained after the administration of single oral doses. Several of the peptidic prodrugs were efficacious against Morganella morganii, Serratia marcescens, penicillin-resistant S. pneumoniae, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, and E. coli infections, with ED50s of 1 to 14 mg/kg by oral administration compared with ED50s of 14 to > 32 mg/kg for the parent molecules. In general, the parent molecules demonstrated greater efficacy than the prodrugs against these same infections when the drugs were administered by the subcutaneous route. The parent molecule was detectable in the sera of mice after oral administration of the peptidic prodrugs.  (+info)

Temporal and multiple quantitative trait loci analyses of resistance to bacterial wilt in tomato permit the resolution of linked loci. (6/6004)

Ralstonia solanacearum is a soil-borne bacterium that causes the serious disease known as bacterial wilt in many plant species. In tomato, several QTL controlling resistance have been found, but in different studies, markers spanning a large region of chromosome 6 showed strong association with the resistance. By using two different approaches to analyze the data from a field test F3 population, we show that at least two separate loci approximately 30 cM apart on this chromosome are most likely involved in the resistance. First, a temporal analysis of the progression of symptoms reveals a distal locus early in the development of the disease. As the disease progresses, the maximum LOD peak observed shifts toward the proximal end of the chromosome, obscuring the distal locus. Second, although classical interval mapping could only detect the presence of one locus, a statistical "two-QTL model" test, specifically adapted for the resolution of linked QTL, strongly supported the hypothesis for the presence of two loci. These results are discussed in the context of current molecular knowledge about disease resistance genes on chromosome 6 and observations made by tomato breeders during the production of bacterial wilt-resistant varieties.  (+info)

The in-vitro activity of HMR 3647, a new ketolide antimicrobial agent. (7/6004)

The in-vitro activity of HMR 3647, a novel ketolide, was investigated in comparison with those of erythromycin A, roxithromycin, clarithromycin (14-membered ring macrolides), amoxycillin-clavulanate and ciprofloxacin against 719 recent clinical Gram-positive, Gram-negative and anaerobic isolates and type cultures. HMR 3647 generally demonstrated greater activity than the other compounds with MIC90s of < or =0.5 mg/L, except for Staphylococcus epidermidis (MIC90 > 128 mg/L), Haemophilus influenzae (MIC90 = 2 mg/L), Enterococcus faecalis (MIC90 = 2 mg/L), Enterococcus faecium (MIC90 = 1 mg/L) and the anaerobes, Bacteroides fragilis (MIC90 = 2 mg/L) and Clostridium difficile (MIC90 = 1 mg/L). In general, an increase in the size of the inoculum from 10(4) to 10(6) cfu on selected strains had little effect on the MICs of HMR 3647. Additionally, the in-vitro activity of HMR 3647 was not affected by the presence of either 20 or 70% (v/v) human serum. The antichlamydial activity of HMR 3647 was generally greater than that of commonly used antichlamydial antimicrobials.  (+info)

Candidate bacterial conditions. (8/6004)

This article provides background information on bacterial diseases and discusses those that are candidates for elimination or eradication. Only one disease, neonatal tetanus, is a strong candidate for elimination. Others, including Haemophilus influenzae b infection, leprosy, diphtheria, pertussis, tuberculosis, meningococcal disease, congenital syphilis, trachoma and syphilis are important causes of morbidity and mortality in industrialized and developing countries. For all these diseases, eradication/elimination is not likely because of the characteristics of the disease and limitations in the interventions.  (+info)

Severe bacterial infections are associated with mortality of about 30%. Patients with moderate to severe bacterial infections given early and appropriate empirical antibiotic treatment are at a lesser risk for a fatal outcome, with odds ratios ranging from 1.6 to 6.9. However only about 2/3 of patients worldwide are given early and appropriate empirical antibiotic treatment. About 40% of patients treated with antibiotics are given superfluous treatment.. TREAT is a computerized decision support system for antibiotic treatment in inpatients with common bacterial infections. TREAT is based on a state of the art stochastic model of the domain (a causal probabilistic network) and uses a cost benefit model for antibiotic treatment, including costs assigned to future resistance. It was tested in a randomized controlled trial in 3 countries and shown to improve the percentage of appropriate empirical antibiotic treatment while at the same time reduce hospital stay and the use of broad-spectrum ...
Nepals Every Newborn Action Plan 2015 aspires to reduce newborn deaths from 21 per 1000 in 2016 to 18.9 per 1,000 live births by 2020 and to 10.9 by 2035. Improving access for early diagnosis and prompt treatment of Possible Severe Bacterial Infection (PSBI) is one of the specific strategies to reduce newborn mortality. National surveys report that mostly preferred choice of
High fever in very young infants should raise the suspicion of a serious bacterial infection, according to research published in The Journal of Emergency Medicine.. In a secondary analysis of the Pediatric Emergency Care Applied Research Network study on febrile infants, researchers evaluated 4821 infants aged up to 8 weeks old. All children had a documented temperature - either taken in the enrolling emergency department, at another health care facility or at home - of 38°C or higher.. The researchers found that the height of fever was associated with an increased risk of bacteraemia, urinary infection or bacterial meningitis (odds ratio, 1.5). Where the temperature was taken was less strongly associated with an increased risk of serious bacterial infection (odds ratio, 1.3), and no association was found with the duration of the fever.. The researchers did note, however, that the height of fever alone was not sufficiently sensitive to rule out a serious bacterial infection. Even children with ...
Brent et al developed the Serious Bacterial Infection (SBI) Score to identify a pediatric patient with a serious bacterial infection. This can help to identify a child who may benefit from more aggressive management. The authors are from Royal College of Paediatrics and Child Health, Imperial College London, University of Leicester, Institute of Health Sciences at Oxford, Oregon Helath & Science University, University of Nottingham and Great Ormond Street Hospital.
IM (intramuscular) sites: There are several sites including midway between the dorsal fin and the lateral line (midline dorsal site), the musculature of the peduncle or flank (towards the tail), or the pectoral fin muscles. My own preference is the pectoral fin muscle, as the drug seems to be quickly taken up with little or no blowback in which the antibiotic comes out of the site as the needle is withdrawn. The drawback with the pectoral fin site is that only small volumes of drug can be injected, which is fine if you are using a low volume dosage antibiotic such as enrofloxacin, but no good for high volume drugs such as Borgal®. This site is not practical with smaller fish because of the lack of muscle in this area. If you are using multiple injections over a period, it is best to alternate the pectoral fin muscle used. Whatever site is chosen, the injection should be done slowly to maximise the deposition of antibiotic ...
Finally, we focused our attention on late infections (occurring after three months post transplantation). Twenty-eight infections were recorded among 22 patients from three months to two years post transplantation. During the first year, 13 severe bacterial infections, 3 fungal infections and 3 cytomegalovirus-reactivation were recorded, while between the first and the second year, only 4 severe bacterial infections developed. The cumulative incidence of first late infection was 14% at three years (Online Supplementary Appendix Figure S2A). By univariate analysis, chronic graft-versus-host disease and the source of cells marginally affected this cumulative incidence: 10 vs. 18% at 6OO days in patients without as compared to patients with chronic graft-versus-host disease (P=0.06). Other tested factors included the source of cell (11% with bone marrow vs. 22% with peripheral blood; P=0.08). Age (older vs. younger than 25 years median age), donor type (sibling vs. others), and total body ...
The Penguin Camera is located on Torgersen Island (64°46S, 64°04W), off the coast of Anvers Island and less than a mile from Palmer Station. Torgersen Island is home to a colony of Adélie penguins numbering approximately 2,500. This camera is seasonal and operates primarily from October to February, the Adélie breeding season. The camera is solar-powered and may sometimes experience brief outages due to inclement weather. School classrooms and other educational demonstrations will often take control of the camera, moving it to gain better views of the colony. ...
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Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The omics approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A
A bacterial infection is an infection caused by bacteria. Bacterial infections can often be treated successfully with antibiotics.. An infection may begin as a bacterial infection. Or a bacterial infection may follow a viral infection that does not get better. When a viral infection doesnt get better for 10 days or more, or when a viral infection starts to improve and then unexpectedly gets worse, a bacterial infection may be more likely.. A bacterial infection usually affects a single area in the body, such as the sinuses, lungs, ears, or urinary tract. Common bacterial infections include sinusitis, pneumonia, strep throat, ear infections, and bladder infections. If untreated, a bacterial infection can spread to the bloodstream. This condition is called bacteremia.. ...
A bacterial infection is an infection caused by bacteria. The distinction is important because bacterial infections are often more serious than other types of infections, such as viral infections, and because bacterial infections can often be treated successfully with antibiotics.Bacterial infections may follow a viral infection that does not improve, or an infection may begin as a bacterial ...
ECCO - European Crohn´s and Colitis Organisation. The European Crohn\s and Colitis Organisation is a highly active non-profit association focusing on Inflammatory Bowel Diseases (IBD).
વજાઈનામાં ઈરિટેશન, સ્વેલિંગ અથવા ઈન્ફેક્શન થવું એક સામાન્ય બાબત છે 25 થી 35 વર્ષની વયની સ્ત્રીઓમાં વજાઇનલ બેક્ટીરિયલ ઈન્ફેક્શન સૌથી વધુ થાય છે શારિરીક સંબંધો દરમિયાન હાઈજિનનું પૂરતું ધ્યાન રાખવામાં ન આવે તો સેક્સ્યુઅલી ટ્રાન્સમિટેડ ડિસીઝ થઈ શકે છે
OBJECTIVE: To evaluate the risk of serious bacterial infections associated with tumor necrosis factor alpha (TNFalpha) antagonists among rheumatoid arthritis (RA) patients. METHODS: A retrospective cohort study of US RA patients enrolled in a large health care organization identified patients who received either TNFalpha antagonists or methotrexate (MTX). Administrative data were used to identify hospitalizations with possible bacterial infections; corresponding medical records were abstracted and reviewed by infectious disease specialists for evidence of definite infections. Proportional hazards models evaluated time-dependent infection risks associated with TNFalpha antagonists. RESULTS: Hospital medical records with claims-identified suspected bacterial infections were abstracted (n=187) among RA patients who received TNFalpha antagonists (n=2,393; observation time 3,894 person-years) or MTX (n=2,933; 4,846 person-years). Over a median followup time of 17 months, the rate of hospitalization with a
The primary endpoint is the acute serious bacterial infection rate defined as the mean number of acute serious bacterial infections per subject per year in the intent-to-treat population. Acute serious bacterial infections will include bacteremia / sepsis, bacterial meningitis, osteomyelitis / septic arthritis, bacterial pneumonia, and visceral abscess, diagnosed according to the Diagnostic Criteria for Serious Acute Bacterial Infections of the US Food and Drug Administration, Center for Biologics Evaluation and Research; Guidance for Industry - Safety, Efficacy, and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement Therapy fo Primary Humoral Immunodeficiency, June 2008 ...
Antibiotic resistant bacterial infections are bacterial infections that are minimally or no longer responsive to commonly used antibiotics. In other words, these bacteria are resistant to antibiotics - they cannot be killed and their growth cannot be stopped. These types of infections are difficult and costly to treat, and sometimes require the use of toxic and dangerous alternatives. These infections may also be passed to other pets or to humans. Antibiotic resistant bacterial infections most commonly affect the skin, the gastrointestinal tract, the urinary tract, or the respiratory tract.. ...
Antibiotic resistant bacterial infections are bacterial infections that are minimally or no longer responsive to commonly used antibiotics. In other words, these bacteria are resistant to antibiotics - they cannot be killed and their growth cannot be stopped. These types of infections are difficult and costly to treat, and sometimes require the use of toxic and dangerous alternatives. These infections may also be passed to other pets or to humans. Antibiotic resistant bacterial infections most commonly affect the skin, the gastrointestinal tract, the urinary tract, or the respiratory tract.. ...
UT Health San Antonios infectious disease specialists have extensive experience in diagnosing and treating minor to severe bacterial infections.
Buy brand Zyvox 600 mg. Generic Zyvox (linezolid) is an antibiotic medication that works to provide quick relief of bacterial infections. Generic Zyvox is most often used to treat complicated skin infections, pneumonia, and other bacterial contaminations. This trusted antibacterial medication is best known for healing severe bacterial infections that do not respond to other antibiotic medications! Generic Zyvox may also be marketed as: Zyvox, ...
Safe drugstore To Buy Cheapest Zyvox. Generic Zyvox (linezolid) is an antibiotic medication that works to provide quick relief of bacterial infections. Generic Zyvox is most often used to treat complicated skin infections, pneumonia, and other bacterial contaminations. This trusted antibacterial medication is best known for healing severe bacterial infections that do not respond to other antibiotic medications! Generic Zyvox may also be marketed as: Zyvox, ...
RTI CLAV 228.5 MG DRY SYRUP 30ML is a combination medicine used to treat a variety of bacterial infections. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid ensures extended anti-bacterial activity. This combination is used to treat severe bacterial infections of the lungs and airways, middle ear, sinuses, skin, and the urinary tract. Buy RTI CLAV 228.5 MG DRY SYRUP 30ML Online. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Download Practo app & get your medicines home delivered.
Growing data suggest that antimicrobial-resistant bacterial infections are common in low- and middle-income countries. This review summarises the microbiology of key bacterial syndromes encountered in West Africa and estimates the prevalence of antimicrobial resistance (AMR) that could compromise first-line empirical treatment. We systematically searched for studies reporting on the epidemiology of bacterial infection and prevalence of AMR in West Africa within key clinical syndromes. Within each syndrome, the pooled proportion and 95% confidence interval were calculated for each pathogen-antibiotic pair using random-effects models. Among 281 full-text articles reviewed, 120 met the eligibility criteria. The majority of studies originated from Nigeria (70; 58.3%), Ghana (15; 12.5%) and Senegal (15; 12.5%). Overall, 43 studies (35.8%) focused on urinary tract infections (UTI), 38 (31.7%) on bloodstream infections (BSI), 27 (22.5%) on meningitis, 7 (5.8%) on diarrhoea and 5 (4.2%) on pneumonia. ...
Growing data suggest that antimicrobial-resistant bacterial infections are common in low- and middle-income countries. This review summarises the microbiology of key bacterial syndromes encountered in West Africa and estimates the prevalence of antimicrobial resistance (AMR) that could compromise first-line empirical treatment. We systematically searched for studies reporting on the epidemiology of bacterial infection and prevalence of AMR in West Africa within key clinical syndromes. Within each syndrome, the pooled proportion and 95% confidence interval were calculated for each pathogen-antibiotic pair using random-effects models. Among 281 full-text articles reviewed, 120 met the eligibility criteria. The majority of studies originated from Nigeria (70; 58.3%), Ghana (15; 12.5%) and Senegal (15; 12.5%). Overall, 43 studies (35.8%) focused on urinary tract infections (UTI), 38 (31.7%) on bloodstream infections (BSI), 27 (22.5%) on meningitis, 7 (5.8%) on diarrhoea and 5 (4.2%) on pneumonia. ...
Its best to check with your doctor to see whether or not your child needs the vaccine. Students who are not up-to-date will not be allowed to attend school until they are vaccinated.. Meningococcal disease is a severe bacterial infection that can lead to meningitis (inflammation of the lining covering the brain and spinal cord) and bloodstream infections such as septicemia. Symptoms of the disease include a high fever, headache, vomiting, a stiff neck and a rash. The meningococcus bacterium is treatable with antibiotics, but each year it causes approximately 2,500 infections and 300 deaths in the United States. Those who contract the disease may experience permanent brain damage, hearing loss, kidney failure, loss of arms or legs, or chronic nervous system problems. The Centers for Disease Control and Prevention has found the highest rates of meningococcal disease to be among preteens, teens, and young adults, as well as among infants with certain medical conditions. The new law targets many in ...
This study involves 106 infants (neonatal period ruled out), victims of severe bacterial infections managed from 1st january 1998 to 30 April 2001 by the four paediatric Mobile Intensive Care Unit (P.M.I.C.U.) teams AP-HP in Ile-de-France area. 46,2% of the whole infants are primary interventions (home, medical room, airport) and primary-secondary interventions (hospital emergencies) whereas 53,8% are related to secondary transports of infants who have been hospitalized and suffered from severe bacterial disorders complicating their original disease. 51% are meningitidis infections, rather due to streptococcus pneumoniae and meningococcis, associated with severe infectious purpura. 20,75% are toxic shock syndromes in patients suffering from chronic affections (sickle cell anemia), acquired or congenital immunodeficiencies ; 19,8% of the cases are severe bacterial pneumonia (staphylococcal pleuro-pneumopathies, bordetella pertussis cough) or surinfected viral infections (VRS bronchiolitis, ...
Emarsa 350 mg Injection is an antibiotic that is used alone or in combination with other medicines to treat severe bacterial infections of the blood, heart, and skin. This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by bacteria only. Buy Emarsa 350 mg Injection Online. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Download Practo app & get your medicines home delivered.
My partner Scott and I should have been sharing our son Edward Gilis first birthday last month. But instead of having that exciting first year to celebrate and many more to look forward to, we had just 9 precious days to spend with our beautiful son.. Edward was cruelly taken from us as a result of contracting group B Strep infection at birth. On average, one newborn baby a day in the UK develops group B Strep infection. One baby a week dies from group B Strep infection. One baby a fortnight who survives the infection is left with long-term disabilities - physical, mental or both. It is the UKs most common cause of severe bacterial infection in newborn babies, and of meningitis in babies under 3 months.. Group B Strep is a normal bacterium carried by around 1/4 women, without symptoms and usually unknowingly. It can be passed from mother to baby around birth with potentially devastating consequences for the baby. But these consequences are usually preventable and thats why Ive started this ...
Babies fed with breast milk containing a particular sugar are more likely to stay protected against severe bacterial infections. Breast milk; a liquid secreted from a mothers body immediately after childbirth, acts as a natural […] ...
Kostmann disease was first described in 1956 as an autosomal recessive disorder characterized by severe neutropenia and onset of severe bacterial infections early in life. In his pivotal doctoral thesis, Rolf Kostmann studied 14 affected children from an inbred family from the province of Norrbotten, Sweden.
Kostmann disease was first described in 1956 as an autosomal recessive disorder characterized by severe neutropenia and onset of severe bacterial infections early in life. In his pivotal doctoral thesis, Rolf Kostmann studied 14 affected children from an inbred family from the province of Norrbotten, Sweden.
Bacterial infections are the most common cause of sepsis. If an infection cannot be prevented, rapid and effective treatment are vital to prevent sepsis.
Abstract The CDC estimates that 65-80% of clinically significant drug resistant bacterial infections are drug refractory due to a change in physiological state of pathogens associated with biofilm formation. TRL1068 is a high affinity (100 pM) native human monoclonal antibody (mAb) that disrupts biofilms by extracting a key bacterial scaffolding protein. The epitope is highly conserved in the target protein homologs across a broad spectrum of gram positive and gram negative bacteria, including all ESKAPE pathogens. The released bacteria regain sensitivity to antibiotics. Biofilm disruption has been demonstrated in vitro for Staphylococcus aureus and for several gram negative species: Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae. In vivo, TRL1068 in combination with an antibiotic vs. antibiotic alone has shown statistically significant efficacy against methicillin resistant S. aureus (MRSA) in two animal models (infected implants in mice and infective endocarditis in ...
Bacterial infections are a major cause of morbidity and mortality worldwide. Innovative approaches to their prevention and management are needed. New treatments have focused on discovering antibiotics but this is problematic given the rise of antimicrobial drug resistance in common bacterial pathogens. Recent attention has been placed on identifying immunomodulatory agents that enhance innate and/or adaptive immune defenses of the infected host.2 The present work by Stables et al advances this immunopharmacology paradigm as it pertains to bacterial infections.1 Their work suggests that one solution may lie within the biology of aspirin. Stables and collaborators used pharmacologic and genetic techniques to determine whether prostaglandin (PG) synthesis and signaling alters host immune responses to infections caused by either group B Streptococcus (GBS) or Streptococcus pneumoniae. Through elegant human and murine studies, Stables et al found that the inhibition of the PG-synthesizing cyclooxygenase-1
Antibacterial agent delivery is of great importance in medicine and dentistry since the bacterial infections are still one of the major reasons for hospitalization and mortality. Despite of the development of technique and pharmacy, more antimicrobial agents are optimized and utilized to treat infections, and their action of principal is better understood which lay a foundation for developing strategies for infection treatment. Over the last decades, many delivery systems have been established to deliver bacterial agents and maintain a sustained activity against them. However, the bacteria are always developing and finding a way to defend themselves. A more responsive antibacterial agent delivery system, which can release the active substances on demand to match the stages of diseases, is highly desirable. Therefore, it motivates us to carry out the work to develop a multifunctional delivery system for antibacterial particle formulation and encapsulation based on the layer-by-layer self-assembly ...
In this study, we have shown that peritoneal macrophages, obtained from patients with cirrhosis and AF, and the presence of bactDNA are primed to synthesise significantly higher amounts of NO than macrophages obtained from patients without bactDNA, and this is associated with marked activation of the cytokines implicated in the type 1 immune response.. Bacterial infections are common complications in patients with advanced cirrhosis, and SBP is the most frequent and clinically relevant.1 The classical pathogenic theory of SBP suggests that bacteria of intestinal origin move across the intestinal wall,5 reaching mesenteric lymph nodes and other organs. Bacteria can then obtain access to AF, and a SBP episode may eventually develop if the local bactericidal mechanisms are insufficient to mount an adequate response.16,17. We have recently described the presence of bactDNA in patients with cirrhosis and culture negative non-neutrocytic AF, a fact that we interpret as molecular evidence of BT.6 It is ...
In fact, there is an emerging literature on the role of bacterial infections in illness and deaths in this flu, and an emerging consensus that bacterial infections are playing a bigger and more serious role than was thought at first. At the ICAAC meeting two weeks ago (more on that soon), KK Johnson et al of the Womens and Childrens Hospital of Buffalo, N.Y., along with researchers from two other institutions, described two severe and ultimately fatal infections with H1N1 complicated by community-strain MRSA. The victims were children, a 9-year-old girl and a 15-year-old boy, who arrived at the emergency room several days after being seen for mild flu symptoms. Both children died of necrotizing pneumonia, one 11 days after being hospitalized and one 3 days. Cite (no link available): K.K. Johnson, H. Faden, P. Joshi, J. F. Fasanello, L. J. Hernan, B.P.Fuhrman, R.C.Welliver, J.K. Sharp and J. J. Schentag, Two Fatal Pediatric Cases of Pandemic H1N1/09 Influenza Complicated by Community-Acquired ...
It is impossible to get rid of bacteria because they are everywhere, including our bodies that have plenty of bad and good bacteria. Infecting organisms try to survive, and to do this they must be looking for other reservoirs and cause infection there. Bacterial infections are transmitted through indirect or direct contact with the reservoir. Effective antibiotics are exceptionally important for us to survive, and that is why we must do anything possible give pathogens no chance to ruin our health ...
I went to the natropathic doctor some months in the past that found Ive Lyme with co-infections. I have started out having silver to battle the bacterial infections And that im getting other supplements and probiotics now. I ended the Deplin and started using B-Suprem by designs for overall health three weeks back. Im feeling a lot more nervous and frustrated now so I dont sense similar to the B-Supreme is sufficient methylated folate. I dont know if my troubles are from being over methylated or from your Lyme and co-bacterial infections. I dont know how to proceed. I want I had commenced with your protocol from the beginning, but undecided how to proceed now. I dont even know When the bacterial infections are even resulting in the problems. Soon after examining many your articles I am not sure if it is the infections resulting in my trouble or getting overmethylated. Do you think these issues are in excess of mythelation ...
The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatment of bacterial infection are also provided.
Bacterial infections are not an uncommon flu complication. Even during normal flu seasons, they pose a very real, even potentially fatal risk to the elderly. This year, however, there has been a spike among Americans with the H1N1 flu. And unlike most of these infections, these seem to pose a real risk to children and younger adults.. November 25, federal health officials cited this troubling spike as they urged more at risk individuals to seek out a vaccine to prevent these secondary infections.. Dr. Anne Schuchat, director of immunization and respiratory disease for the Centers for Disease Control and Prevention, used Denver as an example. Denver is one of ten cities her organization monitors for circulating bacteria strains. In a typical October, the city might have twenty cases of bacterial secondary infections following the flu; this October, they experienced nearly sixty, two thirds of which were in adults under sixty.. Dr. Schuchat spoke not only of this trend and the particulars of the ...
Infections that cannot be spread to others. Many common bacterial infections are not spread to others. Examples are ear, sinus, bladder, or kidney infections. Pneumonia also cannot be passed to others. Sexually transmitted diseases are usually not spread to children. But, they can be spread if there is sexual contact or shared bathing ...
Infections that cannot be spread to others. Many common bacterial infections are not spread to others. Examples are ear, sinus, bladder, or kidney infections. Pneumonia also cannot be passed to others. Sexually transmitted diseases are usually not spread to children. But, they can be spread if there is sexual contact or shared bathing ...
I am a bit overwhelmed about the information, which tests for viral & bacterial infections are advised to get done. So Ive been compiling a list...
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Only one paper was found examining the significance of rigors in febrile children. Children were already judged ill enough to require hospital admission, and so may not be representative of patients presenting directly to the Emergency Department. The diagnosis of presumed bacterial infection in this paper was made on clinical grounds in some children in the absence of positive cultures. All children had blood, urine and stool cultures. No data is given in the paper as to how many children under went lumbar puncture, nor are the results of CSF cultures given. Lumbar puncture was only performed when felt to be clinically indicated. Throat swabs were not taken ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Both strategies will apply to the first 24 weeks in the trial (intervention period).. From week-24 to week-48, the choice of TB tests and the prescription of TB treatment will be left upon the decision of the investigator in both trial arms.. Inclusion time: 24 months. Follow-up: each patient will be followed 48 weeks. Statistical analysis: the primary analysis will be intention to treat. It will compare the 24-week probability of death or invasive bacterial infection between arms.. Sample size: 1050 participants. This will allow demonstration of a 40% reduction in the 24-week probability of death or invasive bacterial infection in arm 2, compared to arm 1 (α 5%; 1-β 80%). ...
British pop star Elton John has cancelled concerts scheduled in the US in April and May after a threatening bacterial infection
Bacterial diseases ; Bacterial infections--Prevention and control ; Infection in children ; Bacterial diseases in children ; Primary care (Medicine)
Serum resistin levels were significantly elevated in patients with Gram-positive, as compared with Gram-negative, septic shock (P = 0.004). Analyses of tissue biopsies revealed that resistin was highly expressed at the local site of infection. Dual-staining for cell markers confirmed published findings that monocytes are a source of resistin in humans, but importantly the stainings revealed that the majority of resistin-producing cells were negative for the monocytic marker CD68. Further analyses identified these cells as neutrophils. A positive correlation between resistin levels and neutrophil counts was found in blood of septic shock patients (P = 0.005). In vitro cell cultures revealed resistin release by neutrophils stimulated with lipopolysaccharide or superantigens. ...
Antibiotic resistant bacterial infections are bacterial infections that are minimally or no longer responsive to commonly used antibiotics. In other words, these bacteria are resistant to antibiotics - they cannot be killed and their growth cannot be stopped. These types of infections are difficult and costly to treat, and sometimes require the use of toxic and dangerous alternatives. These infections may also be passed to other pets or to humans. Antibiotic resistant bacterial infections most commonly affect the skin, the gastrointestinal tract, the urinary tract, or the respiratory tract.. ...
TY - JOUR. T1 - Ceftriaxone therapy of serious bacterial infections in adults. AU - Bittner, M. J.. AU - Dworzack, D. L.. AU - Preheim, L. C.. AU - Tofte, R. W.. AU - Crossley, K. B.. PY - 1983. Y1 - 1983. N2 - We evaluated the efficacy and safety of ceftriaxone in 50 adults with serious infections, usually giving 1 g every 12 h. Of the 35 patients who could be evaluated for clinical efficacy, 15 had failed on previous therapy, 15 had nosocomial infections, and all but 1 had underlying diseases. One patient had three sites of infection. Favorable responses were seen in 34 of 37 infections, including 11 of 13 respiratory tract infections, all 7 urinary tract infections, all 12 skin and soft tissue infections, 1 of 2 bone and joint infections, a catheter-related septicemia, a liver abscess, and an otitis media and externa. Favorable bacteriological responses were seen for 48 of 58 organisms. This included 6 of 7 Staphylococcus aureus strains, 14 of 16 other aerobic gram-positive cocci, 18 of 20 ...
Some children get serious bacterial infections that require hospitalization and then a long course of antibiotics to completely treat the infection. Examples of these serious infections include ruptured appendicitis (when the appendix gets inflamed and bursts, releasing bacteria into the abdomen), complicated pneumonia (when an infected pocket of pus forms either in the lung or between the lung and chest wall), and osteomyelitis (an infection of the bone).
Chronic bacterial prostatitis (CBP) represents a bacterial infection of the prostate gland. CBP causes an associated symptom complex, the hallmark of which is the occurrence of relapsing urinary tract infections, usually involving the same pathogen.
How Much Cost Generic Zyvox Drug. Generic Zyvox (linezolid) is an antibiotic medication that works to provide quick relief of bacterial infections. Generic Zyvox is most often used to treat complicated skin infections, pneumonia, and other bacterial contaminations. This trusted antibacterial medication is best known for healing severe bacterial infections that do not respond to other antibiotic medications! Generic Zyvox may also be marketed as: Zyvox, ...
Early administration of appropriate antimicrobials has been correlated with a better prognosis in patients with bacteremia, but the optimum timing of early antibiotic administration as one of the resuscitation strategies for severe bacterial infections remains unclear. In a retrospective cohort study, adults with community-onset bacteremia at the emergency department (ED) were analyzed. Effects of different cutoffs of time to appropriate antibiotic (TtAa) administration after arrival at the ED on 28-day mortality were examined, after adjustment for independent predictors of mortality identified by multivariate regression analysis. Among 2349 patients, the mean (interquartile range) TtAa was 2.0 (|1 to 12) hours. All selected cutoffs of TtAa, ranging from 1 to 96 hours, were significantly associated with 28-day mortality (adjusted odds ratio (AOR), 0.54-0.65, all P | 0.001), after adjustment of the following prognostic factors: fatal comorbidities (McCabe classification), critical illness (Pitt
Abstract: The present invention provides compounds and compositions useful for controlling bacterial biofilms as well as for controlling and/or preventing bacterial infections. The compounds of the invention are pentacyclic acid triterpenes. Methods for controlling biofilms and for controlling and/or preventing bacterial infections are also disclosed. ##STR00001# ...
There are few data on predictors of HIV progression in untreated children in resource-limited settings. Children with HIV Antibiotic Prophylaxis (CHAP) was a randomized trial comparing cotrimoxazole prophylaxis with placebo in HIV-infected Zambian children. The prognostic value of baseline characteristics was investigated using Cox models. Five hundred fourteen children aged 1 to 14 (median 5.5) years contributed 607 years follow-up (maximum 2.6 years). Half were boys, and in 67%, the mother was the primary carer; at baseline, median CD4 percentage was 11% and weight was less than third percentile in 67%. One hundred sixty-five children died (27.2 per 100 years at risk; 95% confidence interval 23.3-31.6). Low weight-for-age, CD4 percentage, hemoglobin, mother as primary carer, current malnutrition, and previous hospital admissions for respiratory tract infections or recurrent severe bacterial infections were independent predictors of poorer survival, whereas oral candidiasis predicted poorer ...
Introduction: The prevalence of cancers has been noted to be on the increase worldwide. In Africa this increase has mainly been attributed to viral infections especially mv. Lymphomas are currently the commonest childhood cancers seen in Uganda. Although chemotherapy remains the most widely used treatment modality for most childhood cancers, it is associated with bone marrow suppression, and this predisposes these children to severe bacterial infections that are fatal if not treated with appropriate antibiotics. This study was therefore set to determine the common bacterial organisms and their sensitivity patterns in children on cancer chemotherapy at the institute. Objective: To determine the prevalence and aetiology of bacteraemia among children with lymphomas initiated on cancer chemotherapy at the UCI. Methods: This was a cross sectional descriptive study, carried out at the UCI, Mulago hospital between November 2008 and March 2009 among children with lymphomas on cancer chemotherapy. A ...
Zasowski EJ, Bassetti M, Blasi F, et al. A Systematic Review of the Effect of Delayed Appropriate Antibiotic Treatment on the Outcomes of Patients With Severe Bacterial Infections [published online ahead of print, 2020 May 22]. Chest. 2020;S0012-3692(20)31497-5. doi:10.1016/j.chest.2020.03.087. Rothrock SG, Cassidy DD, Barneck M, et al. Outcome of Immediate Versus Early Antibiotics in Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis [published online ahead of print, 2020 Jun 24]. Ann Emerg Med. 2020;S0196-0644(20)30337-1. doi:10.1016/j.annemergmed.2020.04.042. Heldner MR, Zuurbier SM, Li B, et al. Prediction of Cerebral Venous Thrombosis with a new clinical score and D-dimer levels [published online ahead of print, 2020 Jun 23]. Neurology. 2020;10.1212/WNL.0000000000009998. doi:10.1212/WNL.0000000000009998. April MD, Arana A, Schauer SG, et al. Ketamine Versus Etomidate and Peri-intubation Hypotension: A National Emergency Airway Registry Study [published online ahead of ...
Ontario Pharmacists Now Able to Give Additional Vaccines Effective Immediately: In participating pharmacies in Ontario, pharmacists can now provide individuals five years of age and older with vaccines-many of which are travel vaccines-that help protect against the following 13 preventable diseases: • Bacille Calmette-Guérin (tuberculosis) • Haemophilus influenzae type B-known as Hib (severe bacterial infection) • Hepatitis A • Hepatitis B • Herpes zoster (shingles) • Human papillomavirus (HPV) • Japanese encephalitis • Meningococcal disease (severe illnesses like infections of the lining of the brain and spinal cord, as well as bloodstream infections caused by a certain bacteria) • Pneumococcal disease (range of infections from ear and sinus to pneumonia and bloodstream) • Rabies • Typhoid • Varicella (chicken pox) • Yellow fever. How does this affect your employee benefits plan? Some of the vaccines require a prescription from a primary care provider like a family ...
MTorrice writes In recent years, increasing numbers of patients worldwide have contracted severe bacterial infections that are untreatable by most available antibiotics. Some of the gravest of these infections are caused by bacteria carrying genes that confer resistance to a broad class of antibiot...
Targeting the immune system to fight cancer is not new: in 1891, New York bone sarcoma surgeon William B. Coley injected a patient with an inoperable malignant tumor with streptococcal organisms. His theory was that the resulting severe bacterial infection, erysipelas, would stimulate the immune system, shrinking the tumor. His hunch was right, and over…
Virulence factors are molecules expressed and secreted by that enable them to colonize the host, evade or inhibit the immune responses of the host, enter into or out of a host cell, and/or obtain …
Olsen Signifils was born on August 18, 2000, in Port-au-Prince, Haiti. Shortly after birth, he developed meningitis, a severe bacterial infection of the brain. This led to uncontrollable seizures and hydrocephalus, a build-up of water in the brain that prompts swelling. Unable to care for Olsen, his 19-year-old mother abandoned him at St. Damien Hospital.
Bacterial infections are not an easy condition to have because some of the worse kinds have the capacity to take away life if the infection is not immediately treated. There are moderate kinds of bacterial infections, and there are also worse kinds of bacterial infections. Regardless of what infection you have developed, it is necessary that you treat your infection as soon as possible to prevent spread and growth of your infection. Using amoxicillin 500mg will help you in eliminating the bacteria that has cause the infection. Amoxicillin 500mg is an antibiotic drug that is very effective in eliminating a wide range of bacterial infections. Click to continue…. ...
Chronic bacterial infections are inherently resistant to treatment. This is true even if organisms are antibiotic-sensitive, and high concentrations of drugs re...
Flagyl Cure For Vaginal Bacterial Infection, When I was very small, I was terrified of dying and what followed afterward. I remember I often could not sleep from thinking about the big empty nothingness that lay before me, Flagyl Cure For Vaginal Bacterial Infection australia. 200mg Flagyl Cure For Vaginal Bacterial Infection, I was an emo back when it used to mean something.. As I got older, 20mg Flagyl Cure For Vaginal Bacterial Infection, 10mg Flagyl Cure For Vaginal Bacterial Infection, rather than confronting the inevitability of it all I chose to remain distracted and I stayed distracted for a long time but as I get older still I think Im finally taking those few tentative steps on my way to coming to terms with it. Perhaps through realising our own mortality we all experience the seven stages of grief stretching out over our entire lifetime, 30mg Flagyl Cure For Vaginal Bacterial Infection. 1000mg Flagyl Cure For Vaginal Bacterial Infection, A poignant observation perhaps, but hard to ...
Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies.. In this thesis, different aspects of CoNS in hematological malignancy have been studied in four papers:. In paper 1, CoNS blood culture isolates from patients with hematological malignancies treated at the University Hospital of Örebro from 1980 to 2009 were revaluated for the presence of reduced sensitivity to glycopeptides. A high incidence of heterogeneous-intermediate glycopeptide resistance was observed and there was a trend towards increasing incidence of this phenotype over time.. In paper 2, the colonization pattern of CoNS among patients undergoing intensive chemotherapy for hematological malignancy was investigated. A successive homogenization and an accumulation of CoNS phenotypes mutually present in a majority of included patients were demonstrated.. In paper 3, a PCR method to determine ...
Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies.. In this thesis, different aspects of CoNS in hematological malignancy have been studied in four papers:. In paper 1, CoNS blood culture isolates from patients with hematological malignancies treated at the University Hospital of Örebro from 1980 to 2009 were revaluated for the presence of reduced sensitivity to glycopeptides. A high incidence of heterogeneous-intermediate glycopeptide resistance was observed and there was a trend towards increasing incidence of this phenotype over time.. In paper 2, the colonization pattern of CoNS among patients undergoing intensive chemotherapy for hematological malignancy was investigated. A successive homogenization and an accumulation of CoNS phenotypes mutually present in a majority of included patients were demonstrated.. In paper 3, a PCR method to determine ...
CN) - Researchers said Thursday that potentially deadly bacterial infections are on the rise among children in the United States as rates of antibiotic resistance increase.. In a study published in the Journal of the Pediatric Infectious Diseases Society, researchers analyzed the resistance rates to several classes of antibiotics among isolates of Pseudomonas aeruginosa, a type of bacteria that is a common cause of health care-associated infections.. Using data collected from pediatric patients nationwide, the team found that P. aeruginosa bacteria became more resistant to several classes of antibiotics between 1999 and 2012, including doubling their resistance to carbapenems - a class of antibiotics that are considered a last-resort treatment for highly resistant infections.. Highly drug-resistant P. aeruginosa infections leave health care providers with limited - or sometimes no - antibiotic choices available, and these antibiotics are less safe and more toxic in children, study co-author ...
Despite the extensive use of antibiotic agents and the existence of vaccination programs, infectious diseases, particularly bacterial infections are still a major cause of death worldwide. Indeed, because of the massive and often inadequate use of antibiotics, pathogenic bacteria have developed resistance mechanisms against most classes of currently available antibiotics. This trend has been particularly dramatic over the past twenty years. The possible transmission of genes that encode the mechanisms of resistance between different bacterial species has led to the emergence of multiresistant bacteria. This situation causes problems in therapy, particularly in hospitals, The recent and continuous emergence of conventionally used antibiotic-resistant strains in clinic is a serious public health issue. It is urgent new antibacterial agents be discovered. Such molecules must be targeted to proteins that are essential for cell viability, but absent in mammals.. The main objects of this research work ...
The technique represents a viable alternative to antibiotics for the treatment of bacterial infection, using naturally occurring viruses called bacteriophages eaters of bacteria, or phages for short.. Researchers at the University of Leicester have isolated phages that specifically target C.diff, an infection of the gut that killed 1,646 in the UK last year. In lab tests, funded by the Medical Research Council, the viruses were 90 per cent effective against the most dangerous strains of the bug.. The danger posed by growing resistance to antibiotics is one of the gravest health risks facing the world, doctors have warned, and alternative methods for treating bacterial infections are being urgently sought.. Dr Martha Clokie, who led the research at Leicesters Department of Infection, Immunity and Inflammation, said that phages could have a major role to play in coming decades.. The future impact of antibiotics is dwindling at a pace that no one anticipated, with more and more bacteria ...
University of California School of Veterinary Medicine, Department of Medicine and Epidemiology, Davis, CA 95616 Introduction and Objectives. Bacterial infections are the leading cause of death in foals during the first month of life. Ceftiofur, a 3rd-generation cephalosporin, shows excellent in vitro activity against many Gram-positive and Gram-negative bacteria, including E. coli, Actinobacillus spp, and other important pathogens of neonatal foals. This antimicrobial has recently been approved for treating Streptococcal respiratory tract infections in horses at a 24-hour dosage interval and at doses (2.2 to 4.4 mg/kg IM) substantially lower than those recommended for use of other 3rd-generation cephalosporins. The pharmacokinetics of ceftiofur administered IM to foals and adult horses have been reported, but no data is available concerning the pharmacokinetics of ceftiofur after IV use, the preferred administration route for critically ill foals.. The objectives of this study were:. 1. To ...
Since the serendipitous discovery of the first antibiotic, the wonder drug penicillin by Alexander Fleming, bacteria over time have slowly developed resistance to most antibiotics through three well coordinated processes. Firstly, bacteria can evolve their genetic makeup to become resistant against antibiotics; Secondly, bacteria can relay the modified antibiotic resistant genes to other bacteria and other species through a process called conjugation. Thirdly, bacteria quickly give up their individuality to become a part of a team to form surface attached multicellular communities known as biofilms. Bacteria residing within biofilms are protected by a layer of slime which renders the bacteria one thousand fold more resistant to the action of antibiotics. Nearly eighty percent of bacterial infections are associated with biofilms and therefore understandably, biofilms are considered as one of the seven most important health issues facing mankind in the 21st century. The focus of research work presented
Most common infection, most are transient with few untoward sequelae.. Some are life threatening (e.g., Meningoccus, Diphtheria). Severe, recurrent, disseminated or persistent lesions occur in Immunocompromised, organ transplant or AIDS.. Bacterial infections are diagnosed on Clinical grounds, supported by smears, culture, testing for immune responses (Serology) & examining for nucleic acids.. Antibacterial drugs can be effective therapy but, resistance can be a problem (e.g.. MRSA). Continue reading →. ...
Treatment The therapy depends on whether the pneumonia contamination is bacterial, viral, or yeast, and also on how extreme it is. Bacterial infections are usually remedied by taking the full course of prescribed antibiotics much like the directions of the doctor. Antibiotics are often unproductive against viral infections, but can usually be healed simply by taking rest at home for a few days. Fungal infections are cured with the help of antifungal treatments. In order to take care of the particular pneumonia symptoms like fever, soreness, and cough, some over-the-counter medicines may be prescribed to supply comfort and sleep. If the signs are extreme, a hospital stay may be recommended, wherever antibiotics may be given intravenously, as well as oxygen therapy may be given. Additionally, some respiratory treatments may also be carried out, if necessary ...
Health,Researchers from Flanders Interuniversity Institute for Biotechnology ...Bacterial infections are the most common infection which affects p...Researcher Tina mahieu and her colleagues found that certain mice ......,Mice,model,to,study,bacterial,therapeutic,pathway,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Ive always looked at our gut microbiome as a way we achieve optimal health. How is that possible? Well, we know an approach that doesnt work, thats visiting the doctor and obtaining prescriptions for pharmaceutical drugs. What I find fascinating is despite over a trillion dollars of research expenditures, few curative drugs have been invented. You ever thought about that? Antibiotics for bacterial infections are almost the only candidate, and bacteria are already evolving and developing resistance on the current list of antibiotics that we have on the marketplace today ...
Researchers in the School of Dentistry used Hypochlorous acid (HOCl) to produce the webs, known as NETS (neutrophil extracellular traps), from the white blood cells of patients who have a condition in which their cells are unable to produce NETs naturally. The findings are reported in the journal Clinical and Experimental Immunology.. Recent studies have shown that when neutrophils - the white blood cells which form the bodys first line of defence against bacterial infection - are heavily challenged by microbes, they start to die in a specially controlled way. As a last-ditch measure, they expel their entire DNA from within their nucleus into the surrounding tissue. It is this DNA that forms a sticky spiders web or NET, which also contains enzymes that destroy the bacteria once they are trapped by the NET.. Scientists led by Professor Iain Chapple and Dr Paul Cooper in the Periodontal Research Group at the University of Birmingham discovered that Hypochlorous acid stimulated NET release in ...
Bacterial infections are still the major cause of morbidity and mortality, and innate immunity is the first line of host defense against infections. The long-te...
Signs There are a selection of indicators related to UTIs. Bladder bacterial infections are characterised by an urgent need to empty the bladder. Indications consist of Recurrent urination, burning or discomfort during urination (dysuria), bladder spasms and the feeling of having to urinate even though little if any urine truly arrives out. In some cases, cloudy, bloody or foul-smelling urine, and maybe a delicate fever can accompany a UTI ...
Bacterial infections are a huge problem, particularly in medical settings like hospitals. But one U.S. company, recently bought by a Chinese firm, has come up with a product that could provide a real answer: It all has to do with sharks.. ...
Infections that cannot be spread to others. Many common bacterial infections are not spread to others. Examples are ear, sinus, bladder, or kidney infections. Pneumonia also cannot be passed to others. Sexually transmitted diseases are usually not spread to children. But, they can be spread if there is sexual contact or shared bathing ...
Infection prophylaxis is the idea of using antibiotics and other infection-fighting medications prior to the infection occurring to help prevent it.
Generic Cipro is utilized to treat various microbe disorders like skin tone infections and respiratory infections. It is usually employed to decelerate the anthrax consequences following exposer.. Youll find numerous bacterias reside in our own bodies, Every one of the bacterias arent unsafe. there are some bacterias, which aid health. Bacterial infections plus the Microbial disorders happen, as soon as parasites obtain into your human body as a result of Atmosphere, Normal water, Food or Human associates. Many of a new situations, bacterial infections may become existence unhealthy in addition.. Ciprofloxacin, the medicine, belongs to the substance party Fluoroquinolones. Cipro Floxacin, the antibiotic, battles bacterias in the body. Cipro functions stopping or reducing the manufacturing from the protein thats needed is through the Microbial germs to help survive.. Previous to using Cipro, allow the Doctor understand ones comprehensive record of accomplishment including the ...
Gram-Negative Bacterial Infections; Bacterial Infections, Gram-Negative. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is provided.
The Journal of Antimicrobial Chemotherapy is a journal of the British Society for Antimicrobial Chemotherapy (BSAC) and is among the foremost international journals in antimicrobial research.
The Journal of Antimicrobial Chemotherapy is a journal of the British Society for Antimicrobial Chemotherapy (BSAC) and is among the foremost international journals in antimicrobial research.
OBJECTIVES Nonspecific clinical symptoms frequently lead to suspicion of bacterial infection in critically ill children. Clinicians send bacterial cultures for suspected infection and begin an empiric course of antibiotics while microbiology results are pending. We investigated whether the biomarker procalcitonin could be useful to predict confirmed bacterial infection in critically ill children in the PICU, before culture results are available. DESIGN Prospective, blinded single-center study. SETTING Tertiary PICU and cardiothoracic ICU. PATIENTS There were one hundred forty-four patients with suspected bacterial infections that had bacterial cultures sent by clinicians. INTERVENTIONS Procalcitonin samples were obtained at three time intervals: as close to the time of the initial culture as possible (up to 12 hr after) and 24 and 72 hours after the initial culture. Patients were stratified into clinical outcome groups based on microbiology results and clinical symptoms using Centers for Disease
Jerards cultures show that the infection has spread to some of the cerebral fluid in the ventricles (but not the cyst) as well as his urinary tract. So, the infection is systemic. The doctors have prescribed two stronger anti-biotics for this infection. They are trying to get on top of this infection before it develops into full blown meningitus. ...
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Results. The frequencies of extended MBL expression genotypes did not differ between patients and controls. There were 82 patients with SLE who had high MBL expression genotypes and 43 who had medium and low MBL expression genotypes. Patients with the high MBL expression genotype had renal disorders more frequently than patients in the group with medium and low MBL expression genotypes [54/82 (65.9%) vs 18/43 (41.9%), respectively; p = 0.013] and fewer serious bacterial infections [22/82 (26.8%) vs 20/43 (46.5%); p = 0.030]. Using logistic regression for patients with SLE, a high MBL expression genotype was independently associated with renal disorders (OR 2.49, 95% CI 1.15-5.39, p = 0.021) and had a protective effect against serious bacterial infections (OR 0.29, 95% CI 0.12-0.71, p = 0.007). MBL levels decreased significantly when patients with active SLE reached an inactive stage (1.56 ± 0.55 μg/ml vs 1.08 ± 0.65 μg/ml; p = 0.001), but these levels were still higher than those in controls. ...
Infectious diseases in children living in resource-limited settings are often presumptively managed on the basis of clinical signs and symptoms. Malaria is an exception. However, the interpretation of clinical signs and symptoms in relation to bacterial infections is often challenging, which may lead to an over prescription of antibiotics when a malaria infection is excluded. The present study aims to determine the association between clinical signs and symptoms and basic hematology data, with laboratory confirmed bacterial infections. A health survey was done by study nurses to collect clinical signs/symptoms in febrile (axillary temperature ≥ 37.5 °C) children under - 5 years of age. In addition, blood, stool and urine specimen were systematically collected from each child to perform bacterial culture and full blood cell counts. To determine the association between a bacterial infection with clinical signs/symptoms, and if possible supported by basic hematology data (hemoglobin and leucocyte rates)
Bacterial infections can strike anyone and they can sometimes be fata... A cascade of reactions protects us against infections ...Most of the time our body can overcome bacterial infections. Only a l...Upon contact with a bacterium or a bacterial component the immune sy... Mice that are able to cope with acute inflammations ...,A,step,forward,in,the,fight,against,bacterial,infections,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Study Flashcards On Pharmacology 14-15 - Principle of antimicrobial chemotherapy at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Increasing numbers of bacteria are developing antibiotic resistance. This forms a significant challenge in the battle against bacterial infections. Alvin Lo and Han Remaut (VIB/Vrije Universiteit Brussel) have identified a chemical substance with the potential of acting as a new drug to treat bacterial infections, particularly urinary tract infections. In contrast to the most popular antibiotics, this candidate drug does not destroy pathogenic bacteria, but rather disarms them. The benefit of this new strategy is that other (useful) bacteria are unharmed and there is a lower risk of the development and spread of resistance by bacteria. ...
Inflammatory digestive tract disorder clients are a great sad bunch. They experience via a serious soreness within the intestines that leads to diarrhea, abdominal problems, trapped wind and, sometimes, the loss of their own own colon.. There will be drugs that can end up being used to ease typically the symptoms and set the illness into remission. These people drop into several groups: anti-inflammatory sulfa drugs, steroidal potent drugs, immune system suppressor drugs and antibiotics. Every class of drug possesses its own way of helping the disease, and these components are in short , described below.. Potent sulfa drugs. Potent sulfa drug treatments were first developed with regard to arthritis sufferers and are based on antibacterial sulfonamides, which are sulfer containing compounds. Many years ago, it was thought of which bacterial infections may cause the symptoms connected with arthritis. While the anti-microbial effect of the drugs may possibly have been valuable, researchers noticed ...
... is a bacterial infection that involves the superficial skin. The most common presentation is yellowish crusts on the ... Ibrahim, F; Khan, T; Pujalte, GG (December 2015). "Bacterial Skin Infections". Primary care. 42 (4): 485-99. doi:10.1016/j.pop. ... 843 ISBN 978-1-4160-2973-1 Stulberg DL, Penrod MA, Blatny RA (2002). "Common bacterial skin infections". American Family ... The infection is spread by direct contact with lesions or with nasal carriers. The incubation period is 1-3 days after exposure ...
Jul 2008). "Sitafloxacin hydrate for bacterial infections". Drugs Today (Barc). 44 (7): 489-501. doi:10.1358/dot.2008.44. ... Keating GM (April 2011). "Sitafloxacin: in bacterial infections". Drugs. 71 (6): 731-44. doi:10.2165/11207380-000000000-00000. ...
"Bacterial Infections of Humans". Springer Science+Business Media. Retrieved 25 May 2017. Fountain, Henry (25 January 1996). " ...
"Drugs for bacterial infections". Treatment guidelines from the Medical Letter. 11 (131): 65-74. July 2013. PMID 23797768. " ... Nitrofurantoin exerts greater effects on bacterial cells than mammalian cells because bacterial cells activate the drug more ... abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of ... The efficacy of nitrofurantoin in treating UTIs combined with a low rate of bacterial resistance to this agent makes it one of ...
ISBN 0-8151-3762-1. Stulberg DL, Penrod MA, Blatny RA; Penrod; Blatny (2002). "Common bacterial skin infections". Am Fam ... Cutaneous group B streptococcal infection Cutaneous Pasteurella hemolytica infection Cutaneous Streptococcus iniae infection ... Mycobacterium avium-intracellulare complex infection Mycobacterium haemophilum infection Mycobacterium kansasii infection ... Acanthamoeba infection Amebiasis cutis Ant sting Arachnidism Baker's itch Balamuthia infection Bedbug infestation (bedbug bite ...
Helicobacter pylori bacterial infections; shaken baby syndrome and other forms of child abuse; overlaying, child smothering ... Weber MA, Klein NJ, Hartley JC, Lock PE, Malone M, Sebire NJ (May 31, 2008). "Infection and sudden unexpected death in infancy ... SIDS makes up about 80% of sudden and unexpected infant deaths (SUIDs). Other causes include infections, genetic disorders, and ...
Bacterial skin infections include: Impetigo is a highly contagious bacterial skin infection commonly seen in children. It is ... Bacterial pneumonia is a bacterial infection of the lungs. Urinary tract infection is predominantly caused by bacteria. ... Bacterial pathogens often cause infection in specific areas of the body. Others are generalists. Bacterial vaginosis is caused ... Phage therapy can also be used to treat certain bacterial infections. Infections can be prevented by antiseptic measures such ...
Viral, Bacterial and Infections. Fish Diseases and Disorders. 3. Wallingford and New York: CAB International. pp. 149-175. ISBN ... Salmon lice infection in pink salmon weakens ionic homeostasis in pink salmon smolts. Homeostasis is needed for the internal ... It has been shown, however, that salmon louse infections in fish farming facilities can cause epizootics in wild fish. It is ... High levels of salmon lice infections results in a weaker ion regulation system. The ability to activate an inflammatory ...
Bacterial infections generally require antibiotics. Home remedies for throat irritation include gargling with warm water twice ... It is inflammation of the voice box which can occur from overuse, irritation or an infection. Laryngitis can be a short term ... The majority of cases of laryngitis are due to viral infections which only last a few days. Laryngitis is often a common ... The most common cause of epiglottitis is an infection by the bacteria, H influenza. The condition may present all of a sudden ...
Bacterial infections involving the skin". Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology (5th ed.). McGraw-Hill. ... Laube S, Farrell M (2002). "Bacterial skin infection in the elderly: diagnosis and treatment". Drugs and Aging. 19 (5): 331-42 ... A boil, also called a furuncle, is a deep folliculitis, infection of the hair follicle. It is most commonly caused by infection ... "Staph Infection Causes, Symptoms, Treatment - Staph Infection Diagnosis - eMedicineHealth". eMedicineHealth. Tamir J, Haik J, ...
"Macrophage polarization in bacterial infections." The Journal of Immunology 181.6 (2008): 3733-3739. Mackaness GB: Cellular ... resistance to infection. J Exp Med 1962,116:381-406. Krausgruber, Thomas, et al. "IRF5 promotes inflammatory macrophage ...
doi:10.1016/0140-6736(93)92617-3. De Filippis, Ivano; McKee, Marian L. (2013). Molecular Typing in Bacterial Infections. Humana ... M. fermentans was first described by Ruiter and Wentholt in 1952 from isolate of a human genital infection, which led to the ... Investigations have focused on a possible link to it being a cofactor in HIV infection as well as fibromyalgia, Gulf War ... This new mycoplasma, dubbed M. incognitus was concerning as it could either be an opportunistic co-infection or a sexually ...
CS1 maint: Multiple names: authors list (link) Breuer K, Kapp A, Werfel T (2001). "Bacterial Infections and Atopic Dermatitis ...
Journal of bone and joint infection. 2 (3): 154-159. doi:10.7150/jbji.20425. PMID 28894690. "Bacterial Urinary Tract Infections ... of women have a urinary tract infection in a given year and half of women having at least one infection at some point in their ... Testing for bacteriuria is often performed in those with symptoms of a urinary tract infection. Testing is often done in other ... Salvatore S, Salvatore S, Cattoni E, Siesto G, Serati M, Sorice P, Torella M (June 2011). "Urinary tract infections in women". ...
Fungal and bacterial infections[edit]. It is also helpful in diagnosing: *Fungal infections. Some forms of tinea, such as ... It can also be used to diagnose other fungal infections such as ringworm, Microsporum canis, tinea versicolor; bacterial ... it was in 1925 that the technique was used in dermatology by Margarot and Deveze for the detection of fungal infection of hair ... infections such erythrasma; other skin conditions including acne, scabies, alopecia, porphyria; as well as corneal scratches, ...
Role of infections[edit]. Bacterial[edit]. Main article: Cancer bacteria. Heliobacter pylori is known to cause MALT lymphoma. ... "Chronic bacterial and parasitic infections and cancer: a review". Journal of Infection in Developing Countries. 4 (5): 267-81. ... and inflammation from bacterial infection or other viruses. Each cell has a chance of damage. Cells often die if they are ... Safdar A (1 June 2011). Management of Infections in Cancer Patients. Springer. pp. 478-. ISBN 978-1-60761-643-6. . Retrieved 17 ...
Bacterial infections are treated with antibiotics. Cardiac surgery is often required for congenital heart abnormalities. ... and recurrent infections. Infections are common in children due to problems with the immune system's T-cell-mediated response ... frequent infections, developmental delay, learning problems, and cleft palate. Associated conditions include kidney problems, ...
... during which time sweat and bacteria may cause infection. Bacterial infections can result in cysts. Scarring: Skin tissue ... Infection: A new piercing may take up to 6-9 months before it can be taken out, ...
They have included bacterial blood infections, fever, exacerbation of IBD in people who also had that condition, and mild GI ... Donors must be tested for a wide array of bacterial and parasitic infections. In more than 370 published reports there has been ... Rowan, Karen (October 20, 2012). "'Poop Transplants' May Combat Bacterial Infections". LiveScience.com. Retrieved October 20, ... However using one's own original colonic flora which made them susceptible to the CDI infection in the first place obviously ...
Pathogenesis of bacterial infections in animals. John Wiley & Sons, 2008. Helicobacter brantae at the Encyclopedia of Life LPSN ... Billy Bourke; Sherman, Philip M. (2006). Bacterial Genomes and Infectious Diseases. Humana P.,U.S. ISBN 1-59745-152-5. Terio, K ...
For example, jazz bassist Alfred Gertler had a bacterial infection in his bones after breaking an ankle. A physician in the U.S ... "Combatting Bacterial Infection". LabNews.co.uk. Retrieved 2009-05-05. Pirisi A (2000). "Phage therapy-advantages over ... Phage therapy or viral phage therapy is the therapeutic use of bacteriophages to treat pathogenic bacterial infections. Phage ... As with antibiotic therapy and other methods of countering bacterial infections, endotoxins are released by the bacteria as ...
Bacterial infections in the gastrointestinal system. Genitourinary tract infections. Gonorrhoeae. however this indication is no ... Pefloxacin is a quinolone antibiotic used to treat bacterial infections. Pefloxacin has not been approved for use in the United ... Pefloxacin has been increasingly used as a veterinary medicine to treat microbial infections. Pefloxacin is a broad-spectrum ... fluoroquinolones no longer recommended for treatment of gonococcal infections". MMWR Morb. Mortal. Wkly. Rep. 56 (14): 332-6. ...
Bacterial Infections of Humans:Epidemiology & Control. 1982 at pg 195. Found at https://books.google.com.au/books?id= ...
Diarrhea is most commonly caused by a myriad of viral infections but is also often the result of bacterial toxins and sometimes ... May Combat Bacterial Infections". LiveScience.com. Retrieved 2012-10-20. Bakken, Johan S.; Borody, Thomas; Brandt, Lawrence J ... Yellowing of feces can be caused by an infection known as giardiasis, which derives its name from Giardia, an anaerobic ... Protein and fat come from the colon due to secretion, epithelial shedding and gut bacterial action. These proportions vary ...
Pathogenesis of bacterial infections in animals. Wiley. com, 2008. Helicobacter cholecystus at the Encyclopedia of Life LPSN. ... "Bacterial genomes and infectious diseases." Pediatric research 54.1 (2003): 1-7. Hau, Jann, and Steven J. Schapiro, eds. ...
... or bacterial infection. Elizabeth Ryland-Priestley, still seething from William's remarks, contrived to believe that William ...
Bacterial infections *Enterotoxigenic Escherichia coli. *Salmonella enterica. *Campylobacter. *Shigella. *Yersinia. * ... "Infection and Immunity. 76 (8): 3360-3373. CiteSeerX 10.1.1.596.7265. doi:10.1128/IAI.00187-08. ISSN 0019-9567. PMC 2493210. ...
Antibacterials are used to treat bacterial infections. The drug toxicity to humans and other animals from antibacterials is ... The discovery, development and use of antibacterials during the 20th century has reduced mortality from bacterial infections. ... In medicine, they are used as a treatment for infections such as athlete's foot, ringworm and thrush and work by exploiting ... They are relatively harmless to the host and therefore can be used to treat infections. They should be distinguished from ...
As a more modest example, infections caused by Haemophilus influenzae, a major cause of bacterial meningitis and other serious ... Vaccine burden: Miller E, Andrews N, Waight P, Taylor B (2003). "Bacterial infections, immune overload, and MMR vaccine". Arch ... This may have public health implications, as strategies for preventing infection include vaccination, simple hygiene, and, in ... There is evidence that schizophrenia is associated with prenatal exposure to rubella, influenza, and toxoplasmosis infection. ...
Evans, Alfred S. (2013). Bacterial Infections of Humans: Epidemiology and Control. Springer. p. 605. ISBN 9781475711400. ... The test may be falsely negative within 10 weeks of infection, in those less than 6 months old, and in those who have been ...
Mucosal associated invariant T cells and the immune response to infection. Microbes and Infection. August 2011, 13 (8-9): 742-8 ... Mucosal-associated invariant T-cells: new players in anti-bacterial immunity. Frontiers in Immunology. 2014-10-08, 5: 450. PMC ... Infection and Immunity. 2007-05, 75 (5): 2171-2180. ISSN 0019-9567. PMC 1865739. PMID 17353286. doi:10.1128/IAI.01178-06.. ... Infection : microbiology and management 3rd ed. Malden, Mass.: Blackwell Pub. 2006: 435. ISBN 978-1-4443-2393-1. OCLC 592756309 ...
Infection[edit]. Main article: Pneumococcal infection. S. pneumoniae is part of the normal upper respiratory tract flora. As ... Natural bacterial transformation involves the transfer of DNA from one bacterium to another through the surrounding medium. ... Historically, Haemophilus influenzae has been a significant cause of infection, and both H. influenzae and S. pneumoniae can be ... S. pneumoniae infection stimulates polymorphonuclear leukocytes (granulocytes) to produce an oxidative burst that is ...
PET has been widely used to image bacterial infections clinically by using fluorodeoxyglucose (FDG) to identify the infection- ... Three different PET contrast agents have been developed to image bacterial infections in vivo: [18F]maltose,[19] [18F] ... fluoromaltose as a novel PET tracer for imaging bacterial infection". PLoS ONE. 9 (9): e107951. Bibcode:2014PLoSO...9j7951G. ... Imaging infections with molecular imaging technologies can improve diagnosis and treatment follow-up. ...
... balance as well as treating any bacterial infections that may develop.[33] Dialysis may be needed for kidney failure, and ... Peters, C. J. (December 1998). Infection Control for Viral Haemorrhagic Fevers in the African Health Care Setting (PDF). ... Simpson DI (1977). Marburg and Ebola virus infections: a guide for their diagnosis, management, and control. World Health ... Filoviral infection also interferes with proper functioning of the innate immune system.[50][52] EBOV proteins blunt the human ...
Infections[edit]. The anaerobic bacterial species Cutibacterium acnes (formerly Propionibacterium acnes) contributes to the ... Infection with the parasitic mite Demodex is associated with the development of acne.[30][51] It is unclear whether eradication ... These reinforced the idea amongst dermatologists that bacterial growth on the skin plays an important role in causing acne.[179 ... Possible secondary contributors include hormones, infections, diet, and stress. Studies investigating the impact of smoking on ...
Neonatal conjunctivitis, also known as ophthalmia neonatorum, is a form of conjunctivitis and a type of neonatal infection ... Other bacterial ophthalmia neonatorum should be treated by broad spectrum antibiotics drops and ointment for two weeks. ... Topical therapy is not effective and also does not treat the infection of the nasopharynx.[7][8][9] ... Single injection of ceftriaxone IM or IV should be given to infants born to mothers with untreated gonococcal infection. ...
... by far the most common fungal infection of the mouth, and it also represents the most common opportunistic oral infection in ... "Medically important bacterial-fungal interactions." Nature Reviews Microbiology 8.5 (2010): 340-349. Kourkoumpetis, ... Unusually for candidal infections, there is an absence of predisposing factors such as immunosuppression, and it occurs in ... This is an uncommon form of chronic (more than one month in duration) candidal infection involving multiple areas in the mouth ...
Complications of abortions can be infection, bleeding, pain. There may or may not be problems getting pregnant again; this is ... Koba S, Nowak S (February 1976). "[A case of acute bacterial dysentery with cerebrospinal meningitis]" (in Polish). Wiadomości ... Surgery is needed to remove the embryo or fetus from the womb so the woman does not get an infection. ... Other causes for abortions can be the infection of either the woman or embryo/fetus, or their immune response. Certain diseases ...
The government started hailing the use of enamel tanks as easy to clean, lasting forever, and being devoid of bacterial ... and were therefore especially susceptible to infections in general.[19] Aside from these cases, there is no evidence to ...
... has been introduced into tomato plants and in vivo studies show significant resistance to bacterial wilt and bacterial spot.[27 ... "Heterologous expression of taro cystatin protects transgenic tomato against Meloidogyne incognita infection by means of ... In 2000, the concentration of pro-vitamin A was increased by adding a bacterial gene encoding phytoene desaturase, although the ... "Control of Ethylene Synthesis by Expression of a Bacterial Enzyme in Transgenic Tomato Plants". The Plant Cell. 3 (11): 1187- ...
The distinctive odor of feces is due to bacterial action. Gut flora produces compounds such as indole, skatole, and thiols ( ... as consuming or touching it may result in sickness or infection.[3] Human perception of the odor may be contrasted by a non- ...
Bacterial decolonization. Decolonisation.. Specialty. Infectious disease, infection control. [edit on Wikidata]. By pre- ... Decolonization, also bacterial decolonization, is a medical intervention that attempts to rid a patient of an antimicrobial ... Common sites of bacterial colonization include the nasal passage, groin, oral cavity and skin.[1] ... the likelihood of the patient going on to develop life-threatening health care-associated infections is reduced. ...
Bacterial FISH probes are often primers for the 16s rRNA region. FISH is widely used in the field of microbial ecology, to ... Biofilms, for example, are composed of complex (often) multi-species bacterial organizations. Preparing DNA probes for one ... General process of fluorescent in situ hybridization (FISH) used for bacterial pathogen identification. First, an infected ...
Abel-Santos, E (editor) (2012). Bacterial Spores: Current Research and Applications. Caister Academic Press. ISBN 978-1-908230- ... "Ethylene Oxide Sterilization , Disinfection & Sterilization Guidelines , Guidelines Library , Infection Control ,CDC". www.cdc. ... Further information: Bacterial morphological plasticity. Under conditions of starvation, especially the lack of carbon and ... While the rest of a bacterial cell may stain, the endospore is left colourless. To combat this, a special stain technique ...
"Influenza: Viral Infections: Merck Manual Home Edition". Merck. Retrieved 15 March 2008. ... Ballinger, MN; Standiford, TJ (Sep 2010). "Postinfluenza bacterial pneumonia: host defenses gone awry". J Interferon Cytokine ...
Therefore, macrophage membranes become susceptibile to bacterial infections.[11] Reproductive system[edit]. In experiments with ... pyrene confers enhanced susceptibility to bacterial infection". Environ Research. 146: 173-84. doi:10.1016/j.envres.2015.12.027 ... the body's first line of defense to fight infections. In 2016, the molecular mechanism was uncovered as damage to the ... which is a eucaryotic receptor for bacterial surface structures such as lipoteichoic acid. ...
Gram-positive bacterial infection: Actinobacteria (primarily A00-A79, 001-041, 080-109) ... Bacterial cultures were regarded as Gold standards for detection of MAP. Detection is very limited in fresh tissues, food, and ... One study concluded that MAP "may act as a causative agent, have a role in the context of secondary infection, which may ... Type strain of Mycobacterium avium subspecies paratuberculosis at BacDive - the Bacterial Diversity Metadatabase ...
"Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. 48 (4): 351-361. doi:10.1016/j.jmii.2014.06. ... Mcintosh, M (19 October 2004). "Curdlan and other bacterial (1→3)-β-D-glucans". Applied Microbiology and Biotechnology. 68 (2 ... D-glucan in blood is marketed as a means of identifying invasive or disseminated fungal infections.[21][22][23] This test ... and a negative test does not rule out infection. False positives may occur because of fungal contaminants in the antibiotics ...
... while archaeal flagella appear to have evolved from bacterial type IV pili.[106] In contrast to the bacterial flagellum, which ... some species of methanogens have been suggested to be involved in infections in the mouth,[187][188] and Nanoarchaeum equitans ... Middle, a bacterial or eukaryotic phospholipid: 5, fatty acid chains; 6, ester linkages; 7, D-glycerol moiety; 8, phosphate ... The bacterial flagellum shares a common ancestor with the type III secretion system,[104][105] ...
"Expression and nuclear localization of the TATA-box-binding protein during baculovirus infection". The Journal of General ... bacterial RNA polymerase: rpoB. *eukaryotic RNA polymerase: RNA polymerase II. Termination. (bacterial,. eukaryotic). * ...
The baby's eyes are contaminated during passage through the birth canal from either a chemical cause, or a bacterial infection ... 1982). "Longitudinal studies on chlamydial infections in the first year of life". The Pediatric Infectious Disease Journal. 1 ( ... Topical therapy is not effective and also does not treat the infection of the nasopharynx.[9][10][11] ... Neonatal conjunctivitis, is a form of conjunctivitis and a type of neonatal infection contracted by newborns during delivery. ...
Pneumonia, Atypical Bacterial at eMedicine Pneumonia, Typical Bacterial at eMedicine Memish ZA, Ahmed QA, Arabi YM, Shibl AM, ... No signs and symptoms of lobar consolidation, meaning that the infection is restricted to small areas, rather than involving a ... When comparing the bacterial-caused atypical pneumonias with these caused by real viruses (excluding bacteria that were wrongly ... Chest radiographs (X-ray photographs) often show a pulmonary infection before physical signs of atypical pneumonia are ...
new HIV infections are on the rise, and Cuba's preventive measures appear not to be keeping pace with conditions that favour ... In the 1980s, Cuban scientists developed a vaccine against a strain of bacterial meningitis B, which eliminated what had been a ... Education in Cuba concerning issues of HIV infection and AIDS is implemented by the Cuban National Center for Sex Education. ...
The real danger lies that the psyllid can carry a deadly, bacterial tree disease called Huanglongbing (HLB), also known as ... Also rather important are the viral infections to which some of these ectoparasites serve as vectors such as the aphid- ...
Nikibakhsh, Ahmad (Sep 2011). "16". Clinical Management of Complicated Urinary Tract Infection. doi:10.5772/24859. ISBN 978-953 ... The "No-Touch" technique is unique in that it aims at preventing bacterial contamination of the prosthesis by completely ... Muench, Peter J. (2013). "Infections Versus Penile Implants: The War on Bugs". Journal of Urology. 189 (5): 1631-1673. doi: ... Over 70% of infections form from skin organisms including Staphylococcus epidermis, aureus, streptococcus and Candida albicans. ...
Some diseases, such as tetanus, cause disease not by bacterial growth but by bacterial production of a toxin. Tetanus toxin is ... Immunity against infections that can cause serious illness is generally beneficial. Since Pasteur provided support for a germ ... Temporary immunity to a specific infection can be induced in a subject by providing the subject with externally produced immune ... which is the controlled infection of a subject with a less lethal natural form of smallpox (known as Variola Minor) to make him ...
One of the exotoxins is encoded on the bacterial chromosome, while the other is encoded on a plasmid. These exotoxins are ... The mainstay of treatment for SSSS is supportive care along with eradication of the primary infection. Conservative measures ...
... pyrene confers enhanced susceptibility to bacterial infection. Environmental research. 2016-4, roč. 146, s. 173-184. PMID: ...
They defend against bacterial or fungal infection. They are usually first responders to microbial infection; their activity and ... Infectious diseases - viral (AIDS, SARS, West Nile encephalitis, hepatitis, herpes, measles, others), bacterial (TB, typhoid, ... In HIV infection, these T cells are the main index to identify the individual's immune system integrity. ... Infection. *Chronic inflammation - especially juvenile rheumatoid arthritis, rheumatoid arthritis, Still's disease, Crohn's ...
COPD develops as a significant and chronic inflammatory response to inhaled irritants.[9] Chronic bacterial infections may also ... People with COPD can experience flare-ups that are often triggered by a viral or bacterial respiratory infection.[100] The ... An acute exacerbation (a sudden worsening of symptoms)[62] is commonly triggered by infection or environmental pollutants, or ... Respiratory infections such as pneumonia do not appear to increase the risk of COPD, at least in adults.[23] ...
... bacterial infections can often be treated successfully with antibiotics.Bacterial infections may follow a viral infection that ... The distinction is important because bacterial infections are often more serious than other types of infections, such as viral ... or an infection may begin as a bacterial ... ... A bacterial infection is an infection caused by bacteria. ... Bacterial Infection. A bacterial infection is an infection caused by bacteria. Bacterial infections can often be treated ...
"Most antibiotics used to treat infections in the upper respiratory tract have an impact on the normal bacterial flora," the ... To test the idea, the researchers identified a group of 108 children with frequent ear infections between six months and six ... Paradoxically, repeated courses of antibiotics might contribute to recurrent infections in children who are prone to otitis." ... wondered whether infection-prone children might be treated simply by beefing up their own bodies first line of defense: the ...
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... bacterial infection, discharge - Answer: Go see hour doctor he can take a culture to make sure it is ... ... diflucan, infections, bacterial infection, discharge, period, yeast infection, bacterial, symptom, infection, pill. Details:. ... Home › Q & A › Questions › Diflucan - yeast infection or.... Diflucan - yeast infection or bacterial infection?. Asked. 14 Mar ... Go see hour doctor he can take a culture to make sure it is yeast infection or bacterial. Sometimes you need repeat the ...
But are bacterial infections contagious? The short answer is that some are and some arent. Well tell you what you need to ... How do bacterial infections spread?. Bacterial infections can be acquired in several different ways, depending on the type of ... Types of bacterial infections that arent contagious. Not all bacterial conditions are contagious. This means that they arent ... Many bacterial infections can be treated with a course of antibiotics, although some infections may be more serious. ...
Bacterial Infection. Good day doctor, another question please.. My 3 year CP angel has had some kind of rash in face and on ... Took her to GP and he said it is either a Bacterial Infection or Eczema he then gave me pills to give her so he can see wich ... But he also told me if it is a bacterial infection we have a problem. What does he mean with this??????. Thank you very much. ...
Infection. Communicable Diseases. Bacterial Infections. Cross Infection. Iatrogenic Disease. Disease Attributes. Pathologic ... Severe bacterial infections are associated with mortality of about 30%. Patients with moderate to severe bacterial infections ... Community-associated Infections Health-care Acquired Infections Nosocomial Infections Other: antibiotic treatment of by TREAT/ ... Optimal Antibiotic Treatment of Moderate to Severe Bacterial Infections (CDSS). This study is currently recruiting participants ...
... Dr Erik Johnson If your fish have body sores and ulcers, finrot and ... When your fish are sick with a bacterial infection, or weak and stressed from their long winter fast, it is very important that ... The best treatment for serious cases of bacterial infections is an injection (see other areas of web site for more detail) ... You have to rememeber that they are under stress and because of the winter time, they are more susceptible to infection. Giving ...
Bacterial Infections Therapy Area Pipeline Report contains detailed information on the bacterial infections drug pipeline. This ... Top 5 Companies in Early Stage Bacterial Infections Products Top 5 Companies in Late Stage Bacterial Infections Products Top 5 ... Bacterial Infections Therapy Area Pipeline Report contains detailed information on the bacterial infections drug pipeline. This ... Bacterial Infections Therapy Area Pipeline Report US$ 1,495.00 Sep, 2010 · 3971 pages ...
There are many different types of bacterial infection treatments, which vary depending on the type of bacteria that is causing ... Some infections are very aggressive and can lead to serious complications. For example, meningitis is a bacterial infection ... Yogurt and cheese contain probiotics that help fight infection. The best way to treat bacterial infections is to avoid them. ... Bacterial infections might also be mitigated via a healthy diet and an intake of certain vitamins and minerals. Vitamins A, E, ...
... A bacterial infection is an infection caused by bacteria. Bacterial infections can often be treated ... An infection may begin as a bacterial infection. Or a bacterial infection may follow a viral infection that does not get better ... Common bacterial infections include sinusitis, pneumonia, strep throat, ear infections, and bladder infections. If untreated, a ... a bacterial infection may be more likely.. A bacterial infection usually affects a single area in the body, such as the sinuses ...
Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection ... Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection ... to febrile young infants in order to identify patients at a low risk for invasive bacterial infections (IBI) who are suitable ... IBI was defined as isolation of a bacterial pathogen from the blood or cerebrospinal fluid. ...
Rapid Detection of Urinary Tract Infections via Bacterial Nuclease Activity.. Flenker KS1, Burghardt EL1, Dutta N1, Burns WJ1, ... Rapid and accurate bacterial detection methods are needed for clinical diagnostic, water, and food testing applications. The ... selective detection of bacterial species. With the exception of the use of micrococcal nuclease activity to detect ... wide diversity of bacterial nucleases provides a rich source of enzymes that could be exploited as signal amplifying biomarkers ...
James Clark School of Engineering could prevent bacterial infections using tiny biochemical machines nanofactories that can ... "Stopping Bacterial Infections Without Antibiotics." Medical News Today. MediLexicon, Intl., 28 Jan. 2010. Web.. 18 Mar. 2018. , ... Doing so would trigger the bacteria to try to form an infection before there are enough bacterial cells to do harm. This would ... New research at the A. James Clark School of Engineering could prevent bacterial infections using tiny biochemical machines ...
... bacterial canker, citrus greening, crown gall, and many other diseases share a common mechanism. Each is caused by bacterial ... How to Manage Vascular Bacterial Infections * 1. MANAGING VASCULAR BACTERIAL INFECTIONS A Webinar Hosted by AEA Featuring John ... Pierces disease, bacterial canker, citrus greening, crown gall, and many other diseases share a common mechanism. Each is ... Fields where vascular bacterial diseases become established often have similar environmental and nutritional characteristics. ...
Infections can be caused by organisms such as bacteria and viruses. Though there are many bacteria which are good for the body ... Bacterial And Viral Infections. By Akhil Arya. See all Articles by Abhi rathorGet Updates on Health ClubsGet Updates on Abhi ... Taking good care of the hygiene and sanitation can also keep you away from a number of viral and bacterial infections. Mild ... But in viral infections, antibiotics may not work. Antibiotics do not work on viral infections because these viruses hide ...
Gram-negative bacterial infection refers to a disease caused by gram-negative bacteria. One example is E. coli. It is important ... "Introduction: Bacterial Infections: Merck Manual Home Edition". Mycoplasma at the US National Library of Medicine Medical ... August 2005). "Risk factors for Gram-negative bacterial infections in febrile neutropenia". Haematologica. 90 (8): 1102-9. PMID ... Cook RL, Reid G, Pond DG, Schmitt CA, Sobel JD (September 1989). "Clue cells in bacterial vaginosis: immunofluorescent ...
Whats the difference between a bacterial and viral infection? WebMD explains, and provides information on the causes and ... Treatment of Bacterial and Viral Infections. The discovery of antibiotics for bacterial infections is considered one of the ... Diagnosis of Bacterial and Viral Infections. You should consult your doctor if you think you have a bacterial or viral ... Bacterial and viral infections have many things in common. Both types of infections are caused by microbes -- bacteria and ...
Bacterial Meningitis causes, risk factors, transmission, symptoms, diagnosis, treatment, and prevention ... Bacterial meningitis is very serious and can be deadly. Death can occur in as little as a few hours. Most people recover from ... Common causes of bacterial meningitis vary by age group:. *Newborns: Group B Streptococcus, S. pneumoniae, L. monocytogenes, E ... Later symptoms of bacterial meningitis can be very serious (e.g., seizures, coma). For this reason, anyone who thinks they may ...
The most common bacterial infections in child hood are: Catscratch, Cellulitis, Impetigo, H. Pylori, Strep throat, Tuberculosis ... Occult Bacteremia, Eye infection, Diphtheria, Pertussis (whooping cough), Diarrheal Infections, Epiglottitis ... Bacterial Infections in Childhood. Bacteria (singular bacterium) are any of a group of microscopic organisms that are ... Bacterial Infections in Childhood. Bacteria (singular bacterium ) are any of a group of microscopic organisms that are ...
Bacterial Infections Clinical Research Trial Listings in Immunology Family Medicine Infections and Infectious Diseases Vaccines ... Bacterial Infections Clinical Trials. A listing of Bacterial Infections medical research trials actively recruiting patient ... New Dosages of Inflammatory Markers for the Early Diagnosis of Nosocomial Bacterial Infections of the Newborn ... You or your child may be experiencing Bacterial Conjunctivitis, commonly known as Pink eye. To see if you or your child may ...
Bacterial Infections Clinical Research Trial Listings in Immunology Family Medicine Infections and Infectious Diseases Vaccines ... Bacterial Infections Clinical Trials. A listing of Bacterial Infections medical research trials actively recruiting patient ... Severe bacterial infections are associated with mortality of about 30%. Patients with moderate to severe bacterial infections ... Bacterial Vaginosis/ Yeast infection Multi- Center, phase III trial, comprised of three studies , designed to test the safety ...
Peritonitis may be localised or generalised, and may result from infection (often due to rupture of a hollow organ as may occur ... Peritonitis is treated through surgery; the infection and any damaged tissue are removed. Peritonitis is a serious condition ... The exception is spontaneous bacterial peritonitis, which does not always benefit from surgery and may be treated with ...
Researchers have developed a test using cells from a patient that distinguishes between viral and bacterial infections, and may ... similar to antibiotics that can kill a wide range of bacterial infections, for use against infections such as dengue fever. ... Test can distinguish between viral, bacterial infections. The test can also detect immunity levels in people who have been ... The ability to know whether a person has a viral or bacterial infection could allow doctors to more precisely prescribe ...
Learn about bacterial infections that can make you sick and how to treat them. ... Bacterial vs. Viral Infections: How Do They Differ? (Mayo Foundation for Medical Education and Research) Also in Spanish ... ClinicalTrials.gov: Bacterial Infections (National Institutes of Health) * ClinicalTrials.gov: Fasciitis, Necrotizing (National ... The primary NIH organization for research on Bacterial Infections is the National Institute of Allergy and Infectious Diseases ...
... for other purposes can also prevent the growth of certain bacterial pathogens inside human cells, including those... ... "New route to identify drugs that can fight bacterial infections." Medical News Today. MediLexicon, Intl., 31 Jul. 2014. Web. ... demonstrate a new way of identifying non-antibiotic drugs that could one day help curb bacterial infections. ... shows that known drugs that interfere with host cell properties can stall intracellular bacterial infections. ...
Bacterial Infections synonyms, Bacterial Infections pronunciation, Bacterial Infections translation, English dictionary ... definition of Bacterial Infections. n. 1. a. The invasion of bodily tissue by pathogenic microorganisms that proliferate, ... protozoal infection - any infection caused by a protozoan. respiratory infection, respiratory tract infection - any infection ... infection. [ɪnˈfɛkʃən] n → infection f. risk of infection → risque dinfection. to be resistant to infection → résister à ...
Bacterial skin infections in cats, also known as pyoderma, can be caused by either environmental or internal factors. The staph ... infection is the most common cause of bacterial... ... How to Diagnose and Treat Bacterial Skin Infections in Cats. ... The staph infection is the most common cause of bacterial skin infections.[1] At home, you may be able to diagnose your cats ... Examine your cats skin. A bacterial skin infection can occur on any part of the cats body, including its face and nose. ...
Nail fold infections can be painful and interfere with daily activities. They may also spread around the nail to neighboring ... Antibiotics should be taken to treat bacterial infections of the nail fold. In most cases, acute bacterial paronychia is ... Fungal Nail Fold Infections. Antifungals are used to treat fungal nail infections. Since fungal infections are chronic, the ... Antibacterial soaks are sometimes recommended to prevent secondary bacterial infection.. Related Stories. *Age of psoriasis ...
Essential oils to fight bacterial infections. James Cook University scientists have discovered a technique to apply natural ... He said an increasing number of unplanned surgeries are being performed to fight infections - mostly caused by bacterial ... "Just in the US, about 17 million new biofilm-related infections are reported annually, leading to approximately 550,000 ... Even though synthetic antibiotics have been the best weapon for eradicating microbial infections since the arrival of ...
The inclusion of bacterial fluorescence imaging work into the UPPER/LOWER checklist may help better identify infection in ... The UPPER/LOWER infection checklists look for signs and symptoms of local/superficial infection (UPPER) and deep infection ( ... Local infection involves unhealthy tissue, pain, poor healing, exudate, and reek (UPPER), while deeper infection includes a ... of total health care spending and much of this cost stems from management of bacterial infection.[1] Timely diagnosis of high ...
Bacterial peritonitis is an abdominal infection that involves the peritoneum. The infection requires hospitalization and ... Bacterial peritonitis: This bacterial infection inside of the abdomen involves the inner lining tissue, the peritoneum. ... Common Eye Problems and Infections. Sexually Transmitted Diseases. All. Quizzes Diet and Nutrition Quiz. Heart Disease Quiz. ... Bacterial peritonitis can be spontaneous, such as can occur in people with severe alcoholic liver disease, or be caused by ...
... he may be afflicted by a fungal or bacterial skin infection. Once diagnosed, the infection is easily remedied. ... Skin infections are a common problem for most dogs. If you find that your dog is constantly scratching, licking and biting at ... Your dog can get a fungal infection from a parasite, which can become a bacterial infection and lead to a secondary pyoderma. ... he may be afflicted by a fungal or bacterial skin infection. Once diagnosed, the infection is easily remedied. Some breeds of ...
Würzburg researchers have used this technology to provide new insight into the Salmonella infection process. The study has just ... Technological advances are making the analysis of single bacterial infected human cells feasible, ... Dissecting bacterial infections at the single-cell level. University of Würzburg. Journal. Nature Microbiology. Keywords. * ... And using the new technology, bacterial infections can be studied in unprecedented resolution - namely on the single-cell level ...
Date syrup shows promise for fighting bacterial infections. Microbiology Society. Meeting. Society for General Microbiology ... The date syrup was effective in similar amounts to manuka honey but worked more quickly, inhibiting bacterial growth after six ... which is utilised as a topical antibacterial treatment for wound infection. ... was not as effective at inhibiting bacterial growth. ... Date syrup shows promise for fighting bacterial infections ...
Contribution of bacterial and viral infections to attributable mortality in patients with severe burns: an autopsy series. ... Lachiewicz AM, Hauck CG, Weber DJ, Cairns BA, van Duin D. Bacterial Infections After Burn Injuries: Impact of Multidrug ... encoded search term (Burn Wound Infections) and Burn Wound Infections What to Read Next on Medscape. Related Conditions and ... Topical therapy is often applied to prevent infection and to treat ongoing infections or used as an adjunct to surgical ...
An Evanston Township High School student was diagnosed with a bacterial infection over the weekend, prompting city health ... An Evanston Township High School student was diagnosed with a bacterial infection over the weekend, prompting city health ... Health Department Director Evonda Thomas states that the students infection is transmissible through direct contact with nose ...
Jewish Health have discovered a promising strategy for destroying the molecular scaffolding that can make Pseudomonas bacterial ... infections extremely difficult to treat in cystic fibrosis patients ... Biofilms are a form of bacterial colony in which bacterial cells attach to and live within an extracellular matrix, where ... Once a bacterial community forms a biofilm it becomes much more difficult to treat, said Dr. Nick. We think our discovery ...
  • However, not all bacterial pathogens are contagious . (healthline.com)
  • The LightCycler® SeptiFast test from Roche performs in vitro nucleic acid amplification test for pathogens causing bloodstream infections. (clinicaltrials.gov)
  • This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases. (sciencenewsnet.in)
  • Sexually Transmitted Infections (STIs), also known as Sexually Transmitted Diseases (STDs), are becoming more prevalent. (newopp.org)
  • Bacterial diseases are contagious as well. (sakhiyaskinclinic.com)
  • The purpose of the clinical trial is to show that the combined system TREAT/PCR assays will improve the outcome of inpatients with moderate to severe bacterial infections, while at the same time reducing the use of broad-spectrum antibiotics, with no or little additional costs. (clinicaltrials.gov)
  • What are the clinical signs of antibiotic resistant bacterial infections? (valleyvet.ca)
  • Commenting on the findings, Professor David Isaacs, Clinical Professor of Paediatrics and Child Health at the University of Sydney, said: 'Given the fact that serious bacterial infection is rare and fever is extremely common - and almost always due to viral infections - then, just knowing that the height of the fever is important, is relevant, but doesn't help hugely. (medicinetoday.com.au)
  • For some infections, such as strep throat and whooping cough , you're considered to be contagious when you start to experience symptoms. (healthline.com)
  • In addition, while certain infections, such as tuberculosis or streptococcal pharyngitis (strep throat) are contagious, others, such as urinary infections, are not. (familiprix.com)
  • Patients with moderate to severe bacterial infections given early and appropriate empirical antibiotic treatment are at a lesser risk for a fatal outcome, with odds ratios ranging from 1.6 to 6.9. (clinicaltrials.gov)
  • TREAT is a computerized decision support system for antibiotic treatment in inpatients with common bacterial infections. (clinicaltrials.gov)
  • The best treatment for serious cases of bacterial infections is an injection (see other areas of web site for more detail) given along with feeding good high quality medicated food for two weeks. (koivet.com)
  • UT Health San Antonio is the source for expert, accurate diagnosis and effective treatment for all types of bacterial infections. (uthscsa.edu)
  • Successful treatment is dependent upon the experience, skill, and resources of our bacterial infection experts. (uthscsa.edu)
  • Improving access for early diagnosis and prompt treatment of Possible Severe Bacterial Infection (PSBI) is one of the specific strategies to reduce newborn mortality. (savethechildren.net)
  • Diflucan - How long before Difculan takes away Vaginal Yeast Infection Symptoms? (drugs.com)
  • Other infections, such as chlamydia , can be asymptomatic, meaning they don't present symptoms. (healthline.com)
  • Each person having bacterial infection carries different symptoms and so each person's problem is handled in a customised manner. (sakhiyaskinclinic.com)
  • Condoms are the best protection from STIs, but blood, vaginal secretions and ejaculate can all spread infections. (newopp.org)
  • They have extensive experience in diagnosing and treating minor and severe bacterial infections. (uthscsa.edu)
  • There are several types of bacterial skin infections. (tibot.ai)
  • Lyme disease is an infectious bacterial disease that's spread to humans through the bite of an infected tick. (healthline.com)
  • These infections may also be passed to other pets or to humans. (valleyvet.ca)
  • Kristian Roos and colleagues at Lundby Hospital in Gothenburg, Sweden, wondered whether infection-prone children might be treated simply by beefing up their own bodies' first line of defense: the natural flora in the upper respiratory tract. (scientificamerican.com)
  • Most antibiotics used to treat infections in the upper respiratory tract have an impact on the normal bacterial flora," the authors write. (scientificamerican.com)
  • Antibiotic resistant bacterial infections most commonly affect the skin, the gastrointestinal tract, the urinary tract, or the respiratory tract. (valleyvet.ca)
  • Some conditions that predispose a patient to bacterial infections include atopic dermatitis (skin allergies), diabetes mellitus, chronic upper respiratory infections, idiopathic cystitis, and Cushing's disease. (choicevets.com)
  • What are antibiotic resistant bacterial infections? (valleyvet.ca)
  • Antibiotic resistant bacterial infections are bacterial infections that are minimally or no longer responsive to commonly used antibiotics. (valleyvet.ca)
  • Antibiotic resistant bacterial infections occur naturally, but the frequent and/or inappropriate use of antibiotics accelerates the process. (valleyvet.ca)
  • Dogs that have certain medical conditions and are prescribed antibiotics frequently are at a higher risk for antibiotic resistant bacterial infections. (valleyvet.ca)
  • An infection that does not respond appropriately to an antibiotic is suggestive of an antibiotic resistant bacterial infection. (valleyvet.ca)
  • Antibiotic resistant bacterial infections are diagnosed with a culture and sensitivity test. (valleyvet.ca)
  • Antibiotic resistant bacterial infections are treated based on the culture and sensitivity results and the location and severity of infection. (valleyvet.ca)
  • Although some studies have shown promising results regarding the use of probiotics in treating and preventing antibiotic resistant bacterial infections, there has not been conclusive evidence. (valleyvet.ca)
  • Antibiotics are often used to treat bacterial infections. (healthline.com)
  • These types of infections are difficult and costly to treat, and sometimes require the use of toxic and dangerous alternatives. (valleyvet.ca)
  • You have to rememeber that they are under stress and because of the winter time, they are more susceptible to infection. (koivet.com)
  • Dogs that have had a resistant bacterial infection may be more susceptible to infection again in the future if they have a predisposing condition. (valleyvet.ca)
  • In the case of mild to severe infections, patients may need to take topical antibiotics after consulting the dermatologists. (tibot.ai)
  • BACKGROUND: The aim of the present study was to determine the specific role of different types of bacterial infections (BIs) on the prognosis of cirrhotic patients with acute decompensation (AD). (symptoma.com)
  • So, whenever an infection happens, the wound should be cleaned and washed with soap and further medication is provided to each individual patients. (sakhiyaskinclinic.com)
  • Dermatologists prescribe medicines based on the signs, severity and the reason for the infection. (tibot.ai)
  • The best choice is the prevention of the bacterial infections. (tibot.ai)
  • Infection prevention means avoiding another course of antibiotics that could potentially create a resistant infection. (valleyvet.ca)
  • Infection prevention means preventing another course of antibiotics that could potentially create a resistant infection. (choicevets.com)
  • At present , such data are mostly presented as hospital or other aggregate antibiograms, showing antimicrobial susceptibility testing results by bacterial species. (symptoma.com)
  • As a survival mechanism, bacterial organisms can develop ways to resist antibiotics that they are frequently exposed to over time. (valleyvet.ca)
  • Viruses are responsible for the great majority of current infections such as the common cold, influenza and most cases of sore throats. (familiprix.com)
  • It is the most common type of infection appeared in the soft cells under the skin. (tibot.ai)
  • Bacterial infections can be acquired in several different ways, depending on the type of infection. (healthline.com)
  • This type of infection makes re-swollen bumps' cluster which is pains a lot. (tibot.ai)
  • Hence, bacterial infections are treated with antibacterial antibiotics. (familiprix.com)
  • Fever myth teaser Q : Does having a fever mean your infection is bacterial rather than viral? (symptoma.com)
  • A : A fever usually means you have an infection but it doesn't tell you if it's bacterial or viral. (symptoma.com)
  • High fever in very young infants should raise the suspicion of a serious bacterial infection, according to research published in The Journal of Emergency Medicine . (medicinetoday.com.au)
  • Where the temperature was taken was less strongly associated with an increased risk of serious bacterial infection (odds ratio, 1.3), and no association was found with the duration of the fever. (medicinetoday.com.au)
  • The researchers did note, however, that the height of fever alone was not sufficiently sensitive to rule out a serious bacterial infection. (medicinetoday.com.au)
  • A bacterial infection usually affects a single area in the body, such as the sinuses, lungs, ears, or urinary tract. (webmd.com)